Home Other Building Blocks 496-16-2
496-16-2,MFCD05663714
Catalog No.:AA0032V4

496-16-2 | 2,3-Dihydrobenzofuran

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5g
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$9.00   $7.00
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10g
98%
in stock  
$12.00   $8.00
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25g
98%
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$21.00   $15.00
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100g
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$51.00   $36.00
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500g
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0032V4
Chemical Name:
2,3-Dihydrobenzofuran
CAS Number:
496-16-2
Molecular Formula:
C8H8O
Molecular Weight:
120.1485
MDL Number:
MFCD05663714
SMILES:
c1ccc2c(c1)OCC2
Properties
Properties
 
BP:
188-189°C at 760 mmHg  
Form:
Liquid  
MP:
-21°C  
Refractive Index:
n20/D 1.549(lit.)  
Solubility:
alcohol: soluble  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
101  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
1  
XLogP3:
2.1  

Upstream Synthesis Route

[1]BioorganicandMedicinalChemistry,2004,vol.12,#16,p.4313-4336

[2]Chemistry-AEuropeanJournal,2017,vol.23,#5,p.1044-1047

[3]Synthesis,1988,#12,p.950-952

[4]Patent:US6333324,2001,B1,

[5]Patent:WO2003/82787,2003,A1,.Locationinpatent:Page/Pagecolumn137-138

[6]Synlett,2005,#18,p.2837-2842

[7]Patent:US6235771,2001,B1,

[8]Patent:WO2007/27917,2007,A2,.Locationinpatent:Page/Pagecolumn23-25

[9]Patent:EP1394147,2004,A1,.Locationinpatent:Page92

[1]Patent:EP1792899,2007,A1,.Locationinpatent:Page/Pagecolumn11

[2]Patent:WO2010/41271,2010,A2,.Locationinpatent:Page/Pagecolumn28

[3]LettersinDrugDesignandDiscovery,2013,vol.10,#7,p.561-571

[4]Patent:CN102766135,2017,B,.Locationinpatent:Paragraph0035-0036

[5]JournalofMedicinalChemistry,2002,vol.45,#19,p.4222-4239

[6]Patent:WO2008/151170,2008,A2,.Locationinpatent:Page/Pagecolumn45

[7]Patent:CN106554345,2017,A,.Locationinpatent:Paragraph0032-0033

[8]Patent:WO2008/150953,2008,A1,.Locationinpatent:Page/Pagecolumn29

[1]Patent:EP1334732,2003,A1,

[2]Patent:US2004/18239,2004,A1,

[3]Patent:US10098866,2018,B2,

[4]Patent:US6348485,2002,B1,

[5]BioorganicandMedicinalChemistry,2004,vol.12,#16,p.4313-4336

[1]JournalofMedicinalChemistry,2002,vol.45,#19,p.4222-4239

[2]Patent:US6034239,2000,A,

[3]Patent:EP1199304,2002,A1,.Locationinpatent:Referentialexample1

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[5]Patent:US6162927,2000,A,

[6]Patent:US5767144,1998,A,

[7]Patent:US5622971,1997,A,

[1]JournalofMedicinalChemistry,1997,vol.40,#3,p.322-330

[2]Patent:US2005/187282,2005,A1,.Locationinpatent:Page/Pagecolumn8

Downstream Synthesis Route

[1]Advancedsynthesisandcatalysis,2020

[2]Patent:CN111253355,2020,A.Locationinpatent:Paragraph0027-0028

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[4]ACSCatalysis,2020,p.2124-2130

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[9]AppliedOrganometallicChemistry,2018,vol.32

[10]ChemistryofHeterocyclicCompounds,1984,vol.20,p.835-837    KhimiyaGeterotsiklicheskikhSoedinenii,1984,vol.20,p.1032-1034

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[12]JournaloftheChemicalSociety,1950,p.1836,1841

[13]ZhurnalObshcheiKhimii,1940,vol.10,p.967,969    ChemischesZentralblatt,1941,vol.112,p.891

[14]JournaloftheAmericanChemicalSociety,1951,vol.73,p.4152,4157

[15]DokladyChemistry,1984,vol.275,p.135-136    DokladyAkademiiNaukSSSR,1984,vol.275,p.1098-1100

[16]JournaldeChimiePhysiqueetdePhysico-ChimieBiologique,1991,vol.88,p.2363-2370

[17]ChemischeBerichte,1901,vol.34,p.1808    ChemischeBerichte,1902,vol.35,p.1631

[18]JournalofCatalysis,2013,vol.297,p.272-280

[19]RSCAdvances,2013,vol.3,p.23984-23988

[20]AngewandteChemie-InternationalEdition,2016,vol.55,p.292-296    Angew.Chem.,2016

[21]JournaloftheAmericanChemicalSociety,2016,vol.138,p.12234-12242

[22]GreenChemistry,2017,vol.19,p.749-756

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[24]AppliedCatalysisA:General,2018,vol.559,p.20-29

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[27]Patent:US2018/361370,2018,A1.Locationinpatent:Paragraph0345-0346;0348

[28]Patent:CN111099986,2020,A.Locationinpatent:Paragraph0034;0213-0216

[1]CurrentPatentAssignee:KOWACOMPANY,LTD.-US2010/48610,2010,A1Locationinpatent:Page/Pagecolumn87

[2]CurrentPatentAssignee:SHOUYAOHOLDINGSBEIJINGCOLTD-WO2013/97773,2013,A1Locationinpatent:Paragraph0253

[3]Matsubara,Hiroshi;Yasuda,Shinji;Ryu,Ilhyong[Synlett,2003,#2,p.247-249]

[4]Chatelus[AnnalesdeChimie(Cachan,France),1949,vol.<12>4,p.505,526]

[1]Daukshas,V.K.;Gaidyalis,P.G.;Pyatrauskas,O.Yu.;Gasperavichene,G.A.;Ramanauskas,Yu.Yu.;etal.[PharmaceuticalChemistryJournal,1988,vol.22,#3,p.220-225][Khimiko-FarmatsevticheskiiZhurnal,1988,vol.22,#3,p.303-307]

[2]v.Kostanecki;Lampe;Marschalk[ChemischeBerichte,1907,vol.40,p.3665][ChemischeBerichte,1909,vol.42,p.4485]

[3]CurrentPatentAssignee:PPGINDUSTRIESINC-US5384077,1995,A

[4]CurrentPatentAssignee:HOYACORPORATION-US2004/215024,2004,A1Locationinpatent:Page7

[1]Smith,Keith;El-Hiti,GamalA.;Jayne,AnthonyJ.;Butters,Michael[OrganicandBiomolecularChemistry,2003,vol.1,#13,p.2321-2325]

[2]CurrentPatentAssignee:JOHNSON&JOHNSONINC-WO2007/75567,2007,A1Locationinpatent:Page/Pagecolumn153-154

[3]Chatelus[AnnalesdeChimie(Cachan,France),1949,vol.<12>4,p.505,526]

[4]CurrentPatentAssignee:INNERMONGOLIAJINGDONGPHARMACEUTICAL-CN107721954,2018,ALocationinpatent:Paragraph0038;0039;0040

[1]Patent:US2010/48610,2010,A1.Locationinpatent:Page/Pagecolumn19

[2]Patent:US2010/280013,2010,A1.Locationinpatent:Page/Pagecolumn16

[3]Patent:WO2019/86890,2019,A1.Locationinpatent:Page/Pagecolumn82-83

[4]Patent:US2008/318941,2008,A1.Locationinpatent:Page/Pagecolumn33

[5]Patent:US2008/200471,2008,A1.Locationinpatent:Page/Pagecolumn55-56

[6]JournalofMedicinalChemistry,2008,vol.51,p.6853-6865

[7]JournalofMedicinalChemistry,1986,vol.29,p.2326-2329

[8]OrganicProcessResearchandDevelopment,2012,vol.16,p.1591-1597

[9]Synthesis,1988,p.950-952

[10]Patent:US2009/5431,2009,A1.Locationinpatent:Page/Pagecolumn30;31

[11]AnnalesdeChimie(Cachan,France),1949,vol.<12>4,p.505,526

[12]OrganicandBiomolecularChemistry,2004,vol.2,p.2442-2450

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SDS
Tags:496-16-2 Molecular Formula|496-16-2 MDL|496-16-2 SMILES|496-16-2 2,3-Dihydrobenzofuran