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34031-32-8,MFCD00080759
Catalog No.:AA0037ZN

34031-32-8 | (1-Thio-beta-D-glucopyranosato)(triethylphosphine)gold 2,3,4,6-tetraacetate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$18.00   $13.00
- +
10mg
98%
in stock  
$66.00   $47.00
- +
25mg
≥95%
in stock  
$73.00   $51.00
- +
100mg
≥95%
in stock  
$118.00   $82.00
- +
500mg
≥95%
in stock  
$433.00   $303.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0037ZN
Chemical Name:
(1-Thio-beta-D-glucopyranosato)(triethylphosphine)gold 2,3,4,6-tetraacetate
CAS Number:
34031-32-8
Molecular Formula:
C20H34AuO9PS
Molecular Weight:
678.4839
MDL Number:
MFCD00080759
SMILES:
CC(=O)OCC1OC([S-])C(C(C1OC(=O)C)OC(=O)C)OC(=O)C.CCP(CC)CC.[Au+]
Properties
Computed Properties
 
Complexity:
532  
Covalently-Bonded Unit Count:
3  
Heavy Atom Count:
32  
Hydrogen Bond Acceptor Count:
10  
Rotatable Bond Count:
12  
Undefined Atom Stereocenter Count:
5  

Downstream Synthesis Route
CASUnavailable 
  19879-84-6    554-70-1    34031-32-8 

[1]CurrentPatentAssignee:HUAZHONGUNIVERSITYOFSCIENCE&TECHNOLOGY-CN112538099,2021,ALocationinpatent:Paragraph0018;0063-0065

Literature

Title: Cox AG, et al. The thioredoxin reductase inhibitor auranofin triggers apoptosis through a Bax/Bak-dependent process that involves peroxiredoxin 3 oxidation. Biochem Pharmacol. 2008 Oct 30;76(9):1097-109.

Title: Park SH, et al. Auranofin displays anticancer activity against ovarian cancer cells through FOXO3 activation independent of p53. Int J Oncol. 2014 Oct;45(4):1691-8.

Title: Park N, et al. Auranofin promotes mitochondrial apoptosis by inducing annexin A5 expression and translocation in human prostate cancer cells. J Toxicol Environ Health A. 2014;77(22-24):1467-76.

Title: Lee JC, et al. Effect of auranofin treatment on aberrant splenic interleukin production in adjuvant arthritic rats. J Immunol. 1987 Nov 15;139(10):3268-74.

Title: Shuofeng Yuan, et al. Metallodrug ranitidine bismuth citrate suppresses SARS-CoV-2 replication and relieves virus-associated pneumonia in Syrian hamsters. Nat Microbiol. 2020 Oct 7.

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SDS
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Tags:34031-32-8 Molecular Formula|34031-32-8 MDL|34031-32-8 SMILES|34031-32-8 (1-Thio-beta-D-glucopyranosato)(triethylphosphine)gold 2,3,4,6-tetraacetate