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Title: Indole-3-Carbinol (I3C) enhances the sensitivity of murine breast adenocarcinoma cells to doxorubicin (DOX) through inhibition of NF-κβ, blocking angiogenesis and regulation of mitochondrial apoptotic pathway.
Journal: Chemico-biological interactions 20180625
Title: Agonistic effects of diverse xenobiotics on the constitutive androstane receptor as detected in a recombinant yeast-cell assay.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20180201
Title: Enhancement of colon carcinogenesis by the combination of indole-3 carbinol and synbiotics in hemin-fed rats.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20180201
Title: The promising effect of linagliptin and/or indole-3-carbinol on experimentally-induced polycystic ovarian syndrome.
Journal: Chemico-biological interactions 20170801
Title: Aryl hydrocarbon receptor signaling modifies Toll-like receptor-regulated responses in human dendritic cells.
Journal: Archives of toxicology 20170501
Title: In vitro analysis of factors influencing CYP1A2 expression as potential determinants of interindividual variation.
Journal: Pharmacology research & perspectives 20170401
Title: Epoxyeicosatrienoic acid analog attenuates the development of malignant hypertension, but does not reverse it once established: a study in Cyp1a1-Ren-2 transgenic rats.
Journal: Journal of hypertension 20161001
Title: Global gene expression and morphological alterations in the mammary gland after gestational exposure to bisphenol A, genistein and indole-3-carbinol in female Sprague-Dawley offspring.
Journal: Toxicology and applied pharmacology 20160715
Title: The role dietary of bioactive compounds on the regulation of histone acetylases and deacetylases: a review.
Journal: Gene 20150510
Title: Silibinin induces apoptosis of HT29 colon carcinoma cells through early growth response-1 (EGR-1)-mediated non-steroidal anti-inflammatory drug-activated gene-1 (NAG-1) up-regulation.
Journal: Chemico-biological interactions 20140325
Title: Modifying effects of liver tumor promotion in rats subjected to co-administration of indole-3-carbinol and phenobarbital.
Journal: The Journal of toxicological sciences 20140201
Title: 3,3'-Diindolylmethane inhibits lipopolysaccharide-induced microglial hyperactivation and attenuates brain inflammation.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20140101
Title: Natural indoles, indole-3-carbinol and 3,3'-diindolymethane, inhibit T cell activation by staphylococcal enterotoxin B through epigenetic regulation involving HDAC expression.
Journal: Toxicology and applied pharmacology 20140101
Title: Indole-3-carbinol attenuates the deleterious gestational effects of bisphenol A exposure on the prostate gland of male F1 rats.
Journal: Reproductive toxicology (Elmsford, N.Y.) 20140101
Title: Change in the gene expression of the N-methyl-D-aspartate receptor 2C subunit by dietary β-naphthoflavone, indole-3-carbinol, or acetaminophen in the rat liver.
Journal: The Journal of toxicological sciences 20130101
Title: Screening of drugs to counteract human papillomavirus 16 E6 repression of E-cadherin expression.
Journal: Investigational new drugs 20121201
Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Journal: Bioorganic & medicinal chemistry 20121115
Title: Indole-3-carbinol disrupts estrogen receptor-alpha dependent expression of insulin-like growth factor-1 receptor and insulin receptor substrate-1 and proliferation of human breast cancer cells.
Journal: Molecular and cellular endocrinology 20121105
Title: Target protein interactions of indole-3-carbinol and the highly potent derivative 1-benzyl-I3C with the C-terminal domain of human elastase uncouples cell cycle arrest from apoptotic signaling.
Journal: Molecular carcinogenesis 20121101
Title: In vivo pharmacodynamics of indole-3-carbinol in the inhibition of prostate cancer in transgenic adenocarcinoma of mouse prostate (TRAMP) mice: involvement of Nrf2 and cell cycle/apoptosis signaling pathways.
Journal: Molecular carcinogenesis 20121001
Title: Chronic direct renin inhibition with aliskiren prevents the development of hypertension in Cyp1a1-Ren2 transgenic rats with inducible ANG II-dependent hypertension.
Journal: The American journal of the medical sciences 20121001
Title: Disruptive cell cycle regulation involving epigenetic downregulation of Cdkn2a (p16(Ink4a)) in early-stage liver tumor-promotion facilitating liver cell regeneration in rats.
Journal: Toxicology 20120928
Title: 3,3'-Diindolylmethane, but not indole-3-carbinol, inhibits histone deacetylase activity in prostate cancer cells.
Journal: Toxicology and applied pharmacology 20120915
Title: Antiangiogenic activity of indole-3-carbinol in endothelial cells stimulated with activated macrophages.
Journal: Food chemistry 20120915
Title: In vitro suppression of growth of murine WEHI-3 leukemia cells and in vivo promotion of phagocytosis in a leukemia mice model by indole-3-carbinol.
Journal: Journal of agricultural and food chemistry 20120808
Title: Modulation of carcinogen metabolizing cytochromes P450 in rat liver and kidney by cabbage and sauerkraut juices: comparison with the effects of indole-3-carbinol and phenethyl isothiocyanate.
Journal: Phytotherapy research : PTR 20120801
Title: Modulation of CYP1A1, CYP1A2 and CYP1B1 expression by cabbage juices and indoles in human breast cell lines.
Journal: Nutrition and cancer 20120801
Title: Diindolilmethane (DIM) selectively inhibits cancer stem cells.
Journal: Biochemical and biophysical research communications 20120720
Title: [EGFR-dependent impact of indol-3-carbinol on radiosensitivity of lung cancer cells].
Journal: Zhongguo fei ai za zhi = Chinese journal of lung cancer 20120720
Title: Emerging roles for modulation of microRNA signatures in cancer chemoprevention.
Journal: Current cancer drug targets 20120701
Title: The cruciferous phytoalexins rapalexin A, brussalexin A and erucalexin: chemistry and metabolism in Leptosphaeria maculans.
Journal: Bioorganic & medicinal chemistry 20120701
Title: Effect of indole-3-carbinol on ethanol-induced liver injury and acetaldehyde-stimulated hepatic stellate cells activation using precision-cut rat liver slices.
Journal: Clinical and experimental pharmacology & physiology 20120701
Title: Intestinal lymphangiectasis and lipidosis in rats following subchronic exposure to indole-3-carbinol via oral gavage.
Journal: Toxicologic pathology 20120601
Title: Pharmacokinetic evaluation and in vitro-in vivo correlation (IVIVC) of novel methylene-substituted 3,3' diindolylmethane (DIM).
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120512
Title: B-DIM impairs radiation-induced survival pathways independently of androgen receptor expression and augments radiation efficacy in prostate cancer.
Journal: Cancer letters 20120501
Title: 3,3'-Diindolylmethane suppresses growth of human esophageal squamous cancer cells by G1 cell cycle arrest.
Journal: Oncology reports 20120501
Title: The roles of different porcine cytochrome P450 enzymes and cytochrome b5A in skatole metabolism.
Journal: Animal : an international journal of animal bioscience 20120501
Title: Effect of the pasteurization process on the contents of ascorbigen, indole-3-carbinol, indole-3-acetonitrile, and 3,3'-diindolylmethane in fermented cabbage.
Journal: Journal of agricultural and food chemistry 20120411
Title: Respective roles of CYP2A5 and CYP2F2 in the bioactivation of 3-methylindole in mouse olfactory mucosa and lung: studies using Cyp2a5-null and Cyp2f2-null mouse models.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20120401
Title: Broccoli-derived phytochemicals indole-3-carbinol and 3,3'-diindolylmethane exerts concentration-dependent pleiotropic effects on prostate cancer cells: comparison with other cancer preventive phytochemicals.
Journal: Molecular carcinogenesis 20120301
Title: Hyperglycemia and renin-dependent hypertension synergize to model diabetic nephropathy.
Journal: Journal of the American Society of Nephrology : JASN 20120301
Title: Synthesis and evaluation of the cytotoxicities of tetraindoles: observation that the 5-hydroxy tetraindole (SK228) induces G₂ arrest and apoptosis in human breast cancer cells.
Journal: Journal of medicinal chemistry 20120223
Title: The dietary phytochemical 3,3'-diindolylmethane induces G2/M arrest and apoptosis in oral squamous cell carcinoma by modulating Akt-NF-κB, MAPK, and p53 signaling.
Journal: Chemico-biological interactions 20120205
Title: Direct interactions between intestinal immune cells and the diet.
Journal: Cell cycle (Georgetown, Tex.) 20120201
Title: Indole-3-carbinol synergistically sensitises ovarian cancer cells to bortezomib treatment.
Journal: British journal of cancer 20120117
Title: The rainbow trout liver cancer model: response to environmental chemicals and studies on promotion and chemoprevention.
Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20120101
Title: Imatinib ameliorates renal morphological changes in Cyp1a1-Ren2 transgenic rats with inducible ANG II-dependent malignant hypertension.
Journal: American journal of physiology. Renal physiology 20120101
Title: Tumor angiogenesis as a target for dietary cancer prevention.
Journal: Journal of oncology 20120101
Title: The indolic diet-derivative, 3,3'-diindolylmethane, induced apoptosis in human colon cancer cells through upregulation of NDRG1.
Journal: Journal of biomedicine & biotechnology 20120101
Title: The role of nutraceuticals in chemoprevention and chemotherapy and their clinical outcomes.
Journal: Journal of oncology 20120101
Title: Cigarette-Smoke-Induced Dysregulation of MicroRNA Expression and Its Role in Lung Carcinogenesis.
Journal: Pulmonary medicine 20120101
Title: Novel targets for detection of cancer and their modulation by chemopreventive natural compounds.
Journal: Frontiers in bioscience (Elite edition) 20120101
Title: Diindolylmethane suppresses ovarian cancer growth and potentiates the effect of cisplatin in tumor mouse model by targeting signal transducer and activator of transcription 3 (STAT3).
Journal: BMC medicine 20120101
Title: Ecologically appropriate xenobiotics induce cytochrome P450s in Apis mellifera.
Journal: PloS one 20120101
Title: Marine compounds selectively induce apoptosis in female reproductive cancer cells but not in primary-derived human reproductive granulosa cells.
Journal: Marine drugs 20120101
Title: Arsenic trioxide enhances the radiation sensitivity of androgen-dependent and -independent human prostate cancer cells.
Journal: PloS one 20120101
Title: 3,3'-Diindolylmethane exhibits antileukemic activity in vitro and in vivo through a Akt-dependent process.
Journal: PloS one 20120101
Title: Loss of let-7 up-regulates EZH2 in prostate cancer consistent with the acquisition of cancer stem cell signatures that are attenuated by BR-DIM.
Journal: PloS one 20120101
Title: Gene expression signature of DMBA-induced hamster buccal pouch carcinomas: modulation by chlorophyllin and ellagic acid.
Journal: PloS one 20120101
Title: The safety of cruciferous plants in humans: a systematic review.
Journal: Journal of biomedicine & biotechnology 20120101
Title: 3,3'Diindolylmethane suppresses vascular smooth muscle cell phenotypic modulation and inhibits neointima formation after carotid injury.
Journal: PloS one 20120101
Title: Cigarette smoke exposure-associated alterations to non-coding RNA.
Journal: Frontiers in genetics 20120101
Title: 3,3'-Diindolylmethane induces G1 arrest and apoptosis in human acute T-cell lymphoblastic leukemia cells.
Journal: PloS one 20120101
Title: Activation of thiazide-sensitive co-transport by angiotensin II in the cyp1a1-Ren2 hypertensive rat.
Journal: PloS one 20120101
Title: AHR and the Transcriptional Regulation of Type-17/22 ILC.
Journal: Frontiers in immunology 20120101
Title: Isolated Lymphoid Follicles are Dynamic Reservoirs for the Induction of Intestinal IgA.
Journal: Frontiers in immunology 20120101
Title: Glutathione supplementation attenuates lipopolysaccharide-induced mitochondrial dysfunction and apoptosis in a mouse model of acute lung injury.
Journal: Frontiers in physiology 20120101
Title: Current knowledge on pancreatic cancer.
Journal: Frontiers in oncology 20120101
Title: Role of the Aryl Hydrocarbon Receptor in Controlling Maintenance and Functional Programs of RORγt(+) Innate Lymphoid Cells and Intraepithelial Lymphocytes.
Journal: Frontiers in immunology 20120101
Title: Induction of endoplasmic reticulum stress response by the indole-3-carbinol cyclic tetrameric derivative CTet in human breast cancer cell lines.
Journal: PloS one 20120101
Title: Effects of indole-3-carbinol and phenethyl isothiocyanate on bile and pancreatic juice excretion in rats.
Journal: The journal of medical investigation : JMI 20120101
Title: Activation of AMP-activated protein kinase by 3,3'-Diindolylmethane (DIM) is associated with human prostate cancer cell death in vitro and in vivo.
Journal: PloS one 20120101
Title: Indole-3-carbinol (I3C)-induced apoptosis in nasopharyngeal cancer cells through Fas/FasL and MAPK pathway.
Journal: Medical oncology (Northwood, London, England) 20111201
Title: Cancer chemoprevention by targeting the epigenome.
Journal: Current drug targets 20111201
Title: Suppression of inflammation-associated factors by indole-3-carbinol in mice fed high-fat diets and in isolated, co-cultured macrophages and adipocytes.
Journal: International journal of obesity (2005) 20111201
Title: Indole-3-carbinol inhibited tobacco smoke carcinogen-induced lung adenocarcinoma in A/J mice when administered during the post-initiation or progression phase of lung tumorigenesis.
Journal: Cancer letters 20111201
Title: Interaction of cruciferous phytoanticipins with plant fungal pathogens: indole glucosinolates are not metabolized but the corresponding desulfo-derivatives and nitriles are.
Journal: Phytochemistry 20111201
Title: Dietary ligands of the aryl hydrocarbon receptor induce anti-inflammatory and immunoregulatory effects on murine dendritic cells.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20111201
Title: Transient renin-angiotensin system stimulation in an early stage of life causes sustained hypertension in rats.
Journal: Journal of hypertension 20111201
Title: Indole-3-carbinol and ultraviolet B induce apoptosis of human melanoma cells via down-regulation of MITF.
Journal: Die Pharmazie 20111201
Title: Indole-3-carbinol enhances the resolution of rat liver fibrosis and stimulates hepatic stellate cell apoptosis by blocking the inhibitor of κB kinase α/inhibitor of κB-α/nuclear factor-κB pathway.
Journal: The Journal of pharmacology and experimental therapeutics 20111101
Title: Angiotensin II-dependent hypertension causes reversible changes in the platelet proteome.
Journal: Journal of hypertension 20111101
Title: Indole-3-carbinol inhibits telomerase activity and gene expression in prostate cancer cell lines.
Journal: Anticancer research 20111101
Title: 3,3'-Diindolylmethane induces immunotoxicity via splenocyte apoptosis in neonatal mice.
Journal: Toxicology letters 20111010
Title: Effect of diindolylmethane on Ca(2+) movement and viability in HA59T human hepatoma cells.
Journal: Archives of toxicology 20111001
Title: Enhanced efficacy of gemcitabine by indole-3-carbinol in pancreatic cell lines: the role of human equilibrative nucleoside transporter 1.
Journal: Anticancer research 20111001
Title: Induction of cancer cell death by isoflavone: the role of multiple signaling pathways.
Journal: Nutrients 20111001
Title: Antiandrogenic and growth inhibitory effects of ring-substituted analogs of 3,3'-diindolylmethane (ring-DIMs) in hormone-responsive LNCaP human prostate cancer cells.
Journal: The Prostate 20110915
Title: Relationship between CYP1A induction by indole-3-carbinol or flutamide and liver tumor-promoting potential in rats.
Journal: Archives of toxicology 20110901
Title: Effectiveness of cidofovir intralesional treatment in recurrent respiratory papillomatosis.
Journal: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20110901
Title: Effects of 5,6-benzoflavone, indole-3-carbinol (I3C) and diindolylmethane (DIM) on chemically-induced mammary carcinogenesis: is DIM a substitute for I3C?
Journal: Oncology reports 20110901
Title: Indole-3-carbinol downregulation of telomerase gene expression requires the inhibition of estrogen receptor-alpha and Sp1 transcription factor interactions within the hTERT promoter and mediates the G1 cell cycle arrest of human breast cancer cells.
Journal: Carcinogenesis 20110901
Title: Adjuvant therapy for laryngeal papillomatosis.
Journal: Acta dermatovenerologica Alpina, Pannonica, et Adriatica 20110901
Title: LC-MS/MS quantification of sulforaphane and indole-3-carbinol metabolites in human plasma and urine after dietary intake of selenium-fortified broccoli.
Journal: Journal of agricultural and food chemistry 20110810
Title: 3,3'-Diindolylmethane but not indole-3-carbinol activates Nrf2 and induces Nrf2 target gene expression in cultured murine fibroblasts.
Journal: Free radical research 20110801
Title: Inhibition of soluble epoxide hydrolase improves the impaired pressure-natriuresis relationship and attenuates the development of hypertension and hypertension-associated end-organ damage in Cyp1a1-Ren-2 transgenic rats.
Journal: Journal of hypertension 20110801
Title: [Therapeutic effect of indole-3-carbinol on pig serum-induced hepatic fibrosis in rats].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20110801
Title: Dimer radical cations of indole and indole-3-carbinol: localized and delocalized radical cations of diindolylmethane.
Journal: The journal of physical chemistry. A 20110707
Title: Pharmacodynamics of dietary phytochemical indoles I3C and DIM: Induction of Nrf2-mediated phase II drug metabolizing and antioxidant genes and synergism with isothiocyanates.
Journal: Biopharmaceutics & drug disposition 20110701
Title: MicroRNAs in Human Diseases: From Cancer to Cardiovascular Disease.
Journal: Immune network 20110601
Title: Indole-3-carbinol enhances oxidative stress responses resulting in the induction of preneoplastic liver cell lesions in partially hepatectomized rats initiated with diethylnitrosamine.
Journal: Toxicology 20110510
Title: RuCl₃·3H₂O catalyzed reactions: facile synthesis of bis(indolyl)methanes under mild conditions.
Journal: Molecules (Basel, Switzerland) 20110509
Title: Direct renin inhibition with aliskiren normalizes blood pressure in Cyp1a1-Ren2 transgenic rats with inducible angiotensin ii-dependent malignant hypertension.
Journal: The American journal of the medical sciences 20110501
Title: Enhanced inhibition of lung adenocarcinoma by combinatorial treatment with indole-3-carbinol and silibinin in A/J mice.
Journal: Carcinogenesis 20110401
Title: Antiobesity activities of indole-3-carbinol in high-fat-diet-induced obese mice.
Journal: Nutrition (Burbank, Los Angeles County, Calif.) 20110401
Title: Modulation of rat hepatic and kidney phase II enzymes by cabbage juices: comparison with the effects of indole-3-carbinol and phenethyl isothiocyanate.
Journal: The British journal of nutrition 20110301
Title: Estrogen-like activity of perfluoroalkyl acids in vivo and interaction with human and rainbow trout estrogen receptors in vitro.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20110301
Title: Treatment of recurrent respiratory papillomatosis lung involvement by cidofovir infusion.
Journal: Scandinavian journal of infectious diseases 20110201
Title: Enhancement of renin and prorenin receptor in collecting duct of Cyp1a1-Ren2 rats may contribute to development and progression of malignant hypertension.
Journal: American journal of physiology. Renal physiology 20110201
Title: 3,3'-Diindolylmethane inhibits prostate cancer development in the transgenic adenocarcinoma mouse prostate model.
Journal: Molecular carcinogenesis 20110201
Title: Indole-3-carbinol inhibits hepatic stellate cells proliferation by blocking NADPH oxidase/reactive oxygen species/p38 MAPK pathway.
Journal: European journal of pharmacology 20110115
Title: Brazilian Propolis Suppresses Angiogenesis by Inducing Apoptosis in Tube-Forming Endothelial Cells through Inactivation of Survival Signal ERK1/2.
Journal: Evidence-based complementary and alternative medicine : eCAM 20110101
Title: Renal mechanisms contributing to the antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats with inducible hypertension.
Journal: The Journal of physiology 20110101
Title: Bioactive food components and cancer-specific metabonomic profiles.
Journal: Journal of biomedicine & biotechnology 20110101
Title: Effects of an Indolocarbazole-Derived CDK4 Inhibitor on Breast Cancer Cells.
Journal: Journal of Cancer 20110101
Title: Defined plant extracts can protect human cells against combined xenobiotic effects.
Journal: Journal of occupational medicine and toxicology (London, England) 20110101
Title: Estrogen induced metastatic modulators MMP-2 and MMP-9 are targets of 3,3'-diindolylmethane in thyroid cancer.
Journal: PloS one 20110101
Title: Cruciferous vegetable supplementation in a controlled diet study alters the serum peptidome in a GSTM1-genotype dependent manner.
Journal: Nutrition journal 20110101
Title: The indole-3-carbinol cyclic tetrameric derivative CTet inhibits cell proliferation via overexpression of p21/CDKN1A in both estrogen receptor-positive and triple-negative breast cancer cell lines.
Journal: Breast cancer research : BCR 20110101
Title: Therapeutic Implications of Targeting AKT Signaling in Melanoma.
Journal: Enzyme research 20110101
Title: Medical interventions for high grade vulval intraepithelial neoplasia.
Journal: The Cochrane database of systematic reviews 20110101
Title: Inhibition of fried meat-induced colorectal DNA damage and altered systemic genotoxicity in humans by crucifera, chlorophyllin, and yogurt.
Journal: PloS one 20110101
Title: Alpha-tomatine induces apoptosis and inhibits nuclear factor-kappa B activation on human prostatic adenocarcinoma PC-3 cells.
Journal: PloS one 20110101
Title: Indole-3-carbinol inhibits prostate cancer cell migration via degradation of beta-catenin.
Journal: Oncology research 20110101
Title: How to reduce your cancer risk: mechanisms and myths.
Journal: International journal of general medicine 20110101
Title: Genistein inhibits proliferation of colon cancer cells by attenuating a negative effect of epidermal growth factor on tumor suppressor FOXO3 activity.
Journal: BMC cancer 20110101
Title: Oral carcinogenesis and oral cancer chemoprevention: a review.
Journal: Pathology research international 20110101
Title: Knockdown of MTDH sensitizes endometrial cancer cells to cell death induction by death receptor ligand TRAIL and HDAC inhibitor LBH589 co-treatment.
Journal: PloS one 20110101
Title: Attenuation of multi-targeted proliferation-linked signaling by 3,3'-diindolylmethane (DIM): from bench to clinic.
Journal: Mutation research 20110101
Title: Adipocyte-derived factor as a modulator of oxidative estrogen metabolism: implications for obesity and estrogen-dependent breast cancer.
Journal: In vivo (Athens, Greece) 20110101
Title: Inhibition of Rho-associated coiled-coil containing protein kinase enhances the activation of epidermal growth factor receptor in pancreatic cancer cells.
Journal: Molecular cancer 20110101
Title: Inhibition of premature death by isothiocyanates through immune restoration in LP-BM5 leukemia retrovirus-infected C57BL/6 mice.
Journal: Bioscience, biotechnology, and biochemistry 20110101
Title: Inhibition of fatty acid synthase and Sp1 expression by 3,3'-diindolylmethane in human breast cancer cells.
Journal: Nutrition and cancer 20110101
Title: Understanding carcinogenesis for fighting oral cancer.
Journal: Journal of oncology 20110101
Title: Indole-3-carbinol generates reactive oxygen species and induces apoptosis.
Journal: Biological & pharmaceutical bulletin 20110101
Title: Nigerian foodstuffs with prostate cancer chemopreventive polyphenols.
Journal: Infectious agents and cancer 20110101
Title: Selenium and lung cancer: a systematic review and meta analysis.
Journal: PloS one 20110101
Title: The role of tobacco-derived carcinogens in pancreas cancer.
Journal: ISRN oncology 20110101
Title: Screening the MayBridge Rule of 3 Fragment Library for Compounds That Interact with the Trypanosoma brucei myo-Inositol-3-Phosphate Synthase and/or Show Trypanocidal Activity.
Journal: Molecular biology international 20110101
Title: Deletion of the aryl hydrocarbon receptor enhances the inflammatory response to Leishmania major infection.
Journal: International journal of biological sciences 20110101
Title: Antioxidant N-acetyl-L-cysteine (NAC) supplementation reduces reactive oxygen species (ROS)-mediated hepatocellular tumor promotion of indole-3-carbinol (I3C) in rats.
Journal: The Journal of toxicological sciences 20110101
Title: Effect of Turkish propolis extracts on proteome of prostate cancer cell line.
Journal: Proteome science 20110101
Title: Development of derivatives of 3, 3'-diindolylmethane as potent Leishmania donovani bi-subunit topoisomerase IB poisons.
Journal: PloS one 20110101
Title: Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells.
Journal: Clinical epigenetics 20110101
Title: [The results of adjuvant therapy of juvenile recurring respiratory papillomatosis with the use of indole-3-carbinol].
Journal: Vestnik otorinolaringologii 20110101
Title: THP-1 Macrophages and SGBS Adipocytes - A New Human in vitro Model System of Inflamed Adipose Tissue.
Journal: Frontiers in endocrinology 20110101
Title: Effect of indole-3-carbinol on ethanol-induced liver injury and acetaldehyde-stimulated hepatic stellate cells activation using precision-cut rat liver slices.
Journal: Clinical and experimental pharmacology & physiology 20101201
Title: Gender differences in gemcitabine (Gemzar) efficacy in cancer cells: effect of indole-3-carbinol.
Journal: Anticancer research 20101201
Title: Enhanced urinary angiotensinogen excretion in Cyp1a1-Ren2 transgenic rats with inducible ANG II-dependent malignant hypertension.
Journal: The American journal of the medical sciences 20101101
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters 20101101
Title: A novel indole-3-carbinol derivative inhibits the growth of human oral squamous cell carcinoma in vitro.
Journal: Oral oncology 20101001
Title: Inhibition of lung carcinogenesis and critical cancer-related signaling pathways by N-acetyl-S-(N-2-phenethylthiocarbamoyl)-l-cysteine, indole-3-carbinol and myo-inositol, alone and in combination.
Journal: Carcinogenesis 20100901
Title: Inhibition of cancer cell invasion and metastasis by genistein.
Journal: Cancer metastasis reviews 20100901
Title: Effects of lycopene, indole-3-carbinol, and luteolin on nitric oxide production and iNOS expression are organ-specific in rats.
Journal: Arhiv za higijenu rada i toksikologiju 20100901
Title: 1-Benzyl-indole-3-carbinol is a novel indole-3-carbinol derivative with significantly enhanced potency of anti-proliferative and anti-estrogenic properties in human breast cancer cells.
Journal: Chemico-biological interactions 20100805
Title: Effects of combined treatment with resveratrol and indole-3-carbinol.
Journal: Bulletin of experimental biology and medicine 20100801
Title: Effect of 4-methoxyindole-3-carbinol on the proliferation of colon cancer cells in vitro, when treated alone or in combination with indole-3-carbinol.
Journal: Journal of agricultural and food chemistry 20100728
Title: Radicals and radical ions derived from indole, indole-3-carbinol and diindolylmethane.
Journal: The journal of physical chemistry. A 20100701
Title: 3,3'-diindolylmethane suppresses 12-O-tetradecanoylphorbol-13-acetate-induced inflammation and tumor promotion in mouse skin via the downregulation of inflammatory mediators.
Journal: Molecular carcinogenesis 20100701
Title: A novel mechanism of indole-3-carbinol effects on breast carcinogenesis involves induction of Cdc25A degradation.
Journal: Cancer prevention research (Philadelphia, Pa.) 20100701
Title: Direct inhibition of elastase activity by indole-3-carbinol triggers a CD40-TRAF regulatory cascade that disrupts NF-kappaB transcriptional activity in human breast cancer cells.
Journal: Cancer research 20100615
Title: Automated generation and reactions of 3-hydroxymethylindoles in continuous-flow microreactors.
Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20100611
Title: Synthesis and biological evaluation of a gamma-cyclodextrin-based formulation of the anticancer agent 5,6,11,12,17,18,23,24-octahydrocyclododeca[1,2-b:4,5-b':7,8-b'':10,11-b''']tetraindole (CTet).
Journal: Molecules (Basel, Switzerland) 20100604
Title: The renin-angiotensin system as a primary cause of polyarteritis nodosa in rats.
Journal: Journal of cellular and molecular medicine 20100601
Title: Diet, microRNAs and prostate cancer.
Journal: Pharmaceutical research 20100601
Title: Anticancer properties of indole compounds: mechanism of apoptosis induction and role in chemotherapy.
Journal: Current drug targets 20100601
Title: Regulation of microRNAs by natural agents: an emerging field in chemoprevention and chemotherapy research.
Journal: Pharmaceutical research 20100601
Title: Transient induction of ANG II-dependent malignant hypertension causes sustained elevation of blood pressure and augmentation of the pressor response to ANG II in CYP1A1-REN2 transgenic rats.
Journal: The American journal of the medical sciences 20100601
Title: Chemopreventive properties of indole-3-carbinol, diindolylmethane and other constituents of cardamom against carcinogenesis.
Journal: Recent patents on food, nutrition & agriculture 20100601
Title: Cancer prevention with natural compounds.
Journal: Seminars in oncology 20100601
Title: Pharmacokinetics and enhanced bioavailability of candidate cancer preventative agent, SR13668 in dogs and monkeys.
Journal: Cancer chemotherapy and pharmacology 20100501
Title: The potential efficacy of 3,3'-diindolylmethane in prevention of prostate cancer development.
Journal: European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20100501
Title: Pharmacological exploitation of indole-3-carbinol to develop potent antitumor agents.
Journal: Mini reviews in medicinal chemistry 20100501
Title: The effects of an in utero exposure to 2,3,7,8-tetrachloro-dibenzo-p-dioxin on male reproductive function: identification of Ccl5 as a potential marker.
Journal: International journal of andrology 20100401
Title: Indole-3-carbinol triggers aryl hydrocarbon receptor-dependent estrogen receptor (ER)alpha protein degradation in breast cancer cells disrupting an ERalpha-GATA3 transcriptional cross-regulatory loop.
Journal: Molecular biology of the cell 20100401
Title: AT1 receptor blockade prevents the increase in blood pressure and the augmentation of intrarenal ANG II levels in hypertensive Cyp1a1-Ren2 transgenic rats fed with a high-salt diet.
Journal: The American journal of the medical sciences 20100401
Title: Dioxin-induced changes in epididymal sperm count and spermatogenesis.
Journal: Environmental health perspectives 20100401
Title: Inappropriately high circulating and intrarenal angiotensin II levels during dietary salt loading exacerbate hypertension in Cyp1a1-Ren-2 transgenic rats.
Journal: Journal of hypertension 20100301
Title: Indole-3-carbinol induces apoptosis through p53 and activation of caspase-8 pathway in lung cancer A549 cells.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100301
Title: Sulforaphane but not ascorbigen, indole-3-carbinole and ascorbic acid activates the transcription factor Nrf2 and induces phase-2 and antioxidant enzymes in human keratinocytes in culture.
Journal: Experimental dermatology 20100201
Title: Inhibition of vinyl carbamate-induced pulmonary adenocarcinoma by indole-3-carbinol and myo-inositol in A/J mice.
Journal: Carcinogenesis 20100201
Title: Alteration of microRNA expression in vinyl carbamate-induced mouse lung tumors and modulation by the chemopreventive agent indole-3-carbinol.
Journal: Carcinogenesis 20100201
Title: The role of the Akt/mTOR pathway in tobacco carcinogen-induced lung tumorigenesis.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20100101
Title: Chemoprevention of cigarette smoke-induced alterations of MicroRNA expression in rat lungs.
Journal: Cancer prevention research (Philadelphia, Pa.) 20100101
Title: Indole-3-carbinol inhibits nasopharyngeal carcinoma.
Journal: International journal of toxicology 20100101
Title: Suppression of inflammatory mediators by cruciferous vegetable-derived indole-3-carbinol and phenylethyl isothiocyanate in lipopolysaccharide-activated macrophages.
Journal: Mediators of inflammation 20100101
Title: Cruciferous vegetable intake is inversely associated with lung cancer risk among smokers: a case-control study.
Journal: BMC cancer 20100101
Title: Epigenomic diversity of colorectal cancer indicated by LINE-1 methylation in a database of 869 tumors.
Journal: Molecular cancer 20100101
Title: Serum glutathione transferase does not respond to indole-3-carbinol: A pilot study.
Journal: Therapeutics and clinical risk management 20100101
Title: Diindolylmethane (DIM) spontaneously forms from indole-3-carbinol (I3C) during cell culture experiments.
Journal: In vivo (Athens, Greece) 20100101
Title: Redox regulation in cancer: a double-edged sword with therapeutic potential.
Journal: Oxidative medicine and cellular longevity 20100101
Title: Oxidative stress and autophagy in cardiac disease, neurological disorders, aging and cancer.
Journal: Oxidative medicine and cellular longevity 20100101
Title: 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes induce autophagic cell death in estrogen receptor negative breast cancer.
Journal: BMC cancer 20100101
Title: Antimutagenicity and antiproliferative studies of lipidic extracts from white shrimp (Litopenaeus vannamei).
Journal: Marine drugs 20100101
Title: Effects of a breast-health herbal formula supplement on estrogen metabolism in pre- and post-menopausal women not taking hormonal contraceptives or supplements: a randomized controlled trial.
Journal: Breast cancer : basic and clinical research 20100101
Title: [Approaches to raising efficacy of treatment of patients with chronic prostatitis associated with intracellular infections].
Journal: Urologiia (Moscow, Russia : 1999) 20100101
Title: Minireview: modulation of hormone receptor signaling by dietary anticancer indoles.
Journal: Molecular endocrinology (Baltimore, Md.) 20091201
Title: Cellular signaling perturbation by natural products.
Journal: Cellular signalling 20091101
Title: Harnessing the fruits of nature for the development of multi-targeted cancer therapeutics.
Journal: Cancer treatment reviews 20091101
Title: Targeting of the Akt-nuclear factor-kappa B signaling network by [1-(4-chloro-3-nitrobenzenesulfonyl)-1H-indol-3-yl]-methanol (OSU-A9), a novel indole-3-carbinol derivative, in a mouse model of hepatocellular carcinoma.
Journal: Molecular pharmacology 20091101
Title: Lack of cardiac fibrosis in a new model of high prorenin hyperaldosteronism.
Journal: American journal of physiology. Heart and circulatory physiology 20091101
Title: tert-Butyl 3-[2,2-bis-(ethoxy-carbon-yl)vin-yl]-2-bromo-methyl-1H-indole-1-carboxyl-ate.
Journal: Acta crystallographica. Section E, Structure reports online 20091101
Title: The pneumotoxin 3-methylindole is a substrate and a mechanism-based inactivator of CYP2A13, a human cytochrome P450 enzyme preferentially expressed in the respiratory tract.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20091001
Title: OSU-A9, a potent indole-3-carbinol derivative, suppresses breast tumor growth by targeting the Akt-NF-kappaB pathway and stress response signaling.
Journal: Carcinogenesis 20091001
Title: [Effects of indole-3-carbinol on the outcome of tumor and the changes of anti-oxidative system in null mice grafted with nasopharyngeal carcinoma].
Journal: Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] 20091001
Title: 3,3'-diindolylmethane attenuates colonic inflammation and tumorigenesis in mice.
Journal: Inflammatory bowel diseases 20090801
Title: Low concentrations of diindolylmethane, a metabolite of indole-3-carbinol, protect against oxidative stress in a BRCA1-dependent manner.
Journal: Cancer research 20090801
Title: Dietary chemopreventive phytochemicals: too little or too much?
Journal: Cancer prevention research (Philadelphia, Pa.) 20090701
Title: Angiotensin-converting enzyme is a modifier of hypertensive end organ damage.
Journal: The Journal of biological chemistry 20090605
Title: Indole-3-carbinol improves survival in lupus-prone mice by inducing tandem B- and T-cell differentiation blockades.
Journal: Clinical immunology (Orlando, Fla.) 20090601
Title: The antimicrobial effects of glucosinolates and their respective enzymatic hydrolysis products on bacteria isolated from the human intestinal tract.
Journal: Journal of applied microbiology 20090601
Title: 3,3'-diindolylmethane induction of p75NTR-dependent cell death via the p38 mitogen-activated protein kinase pathway in prostate cancer cells.
Journal: Cancer prevention research (Philadelphia, Pa.) 20090601
Title: Indole-3-carbinol inhibits MDA-MB-231 breast cancer cell motility and induces stress fibers and focal adhesion formation by activation of Rho kinase activity.
Journal: International journal of cancer 20090515
Title: Cell cycle-dependent effects of 3,3'-diindolylmethane on proliferation and apoptosis of prostate cancer cells.
Journal: Journal of cellular physiology 20090401
Title: Evaluation of indole-based probes for high-throughput screening of drug binding to human serum albumin: Analysis by high-performance affinity chromatography.
Journal: Journal of separation science 20090401
Title: Effect of boiling on the content of ascorbigen, indole-3-carbinol, indole-3-acetonitrile, and 3,3'-diindolylmethane in fermented cabbage.
Journal: Journal of agricultural and food chemistry 20090325
Title: Pharmacotherapy of recurrent respiratory papillomatosis: an expert opinion.
Journal: Expert opinion on pharmacotherapy 20090301
Title: Impairment of the autoregulation of renal hemodynamics and of the pressure-natriuresis relationship precedes the development of hypertension in Cyp1a1-Ren-2 transgenic rats.
Journal: Journal of hypertension 20090301
Title: Medical treatment of cervical intraepithelial neoplasia II, III: an update review.
Journal: International journal of clinical oncology 20090201
Title: Indole-3-carbinol inhibits Sp1-induced matrix metalloproteinase-2 expression to attenuate migration and invasion of breast cancer cells.
Journal: Journal of agricultural and food chemistry 20090114
Title: Targeting of aryl hydrocarbon receptor-mediated activation of cyclooxygenase-2 expression by the indole-3-carbinol metabolite 3,3'-diindolylmethane in breast cancer cells.
Journal: The Journal of nutrition 20090101
Title: Anti-adult T-cell leukemia/lymphoma effects of indole-3-carbinol.
Journal: Retrovirology 20090101
Title: Ascorbigen: chemistry, occurrence, and biologic properties.
Journal: Clinics in dermatology 20090101
Title: CYP1B1 mutations in Spanish patients with primary congenital glaucoma: phenotypic and functional variability.
Journal: Molecular vision 20090101
Title: Id2 promotes the invasive growth of MCF-7 and SKOV-3 cells by a novel mechanism independent of dimerization to basic helix-loop-helix factors.
Journal: BMC cancer 20090101
Title: Revealing genes associated with vitellogenesis in the liver of the zebrafish (Danio rerio) by transcriptome profiling.
Journal: BMC genomics 20090101
Title: Induction of G1 and G2/M cell cycle arrests by the dietary compound 3,3'-diindolylmethane in HT-29 human colon cancer cells.
Journal: BMC gastroenterology 20090101
Title: Endothelin receptor blockade does not affect blood pressure or angiotensin II levels in CYP1A1-Ren-2 transgenic rats with acutely induced hypertension.
Journal: Vascular pharmacology 20090101
Title: Modulation of the BRCA1 Protein and Induction of Apoptosis in Triple Negative Breast Cancer Cell Lines by the Polyphenolic Compound Curcumin.
Journal: Breast cancer : basic and clinical research 20090101
Title: Urinary estrogen metabolites and prostate cancer: a case-control study and meta-analysis.
Journal: Journal of experimental & clinical cancer research : CR 20090101
Title: Changes in hippocampal metabolites after effective treatment for fibromyalgia: a case study.
Journal: The Clinical journal of pain 20090101
Title: A combination of indol-3-carbinol and genistein synergistically induces apoptosis in human colon cancer HT-29 cells by inhibiting Akt phosphorylation and progression of autophagy.
Journal: Molecular cancer 20090101
Title: Porcine CYP2A19, CYP2E1 and CYP1A2 forms are responsible for skatole biotransformation in the reconstituted system.
Journal: Neuro endocrinology letters 20090101
Title: Loquat (Eriobotrya japonica) extracts suppress the adhesion, migration and invasion of human breast cancer cell line.
Journal: Nutrition research and practice 20090101
Title: [Effects of indol-3-carbinol and epigallocatexin-3-gallate on alteration and reparation in affected urethra of experimental animals].
Journal: Urologiia (Moscow, Russia : 1999) 20090101
Title: The dietary phytochemical indole-3-carbinol is a natural elastase enzymatic inhibitor that disrupts cyclin E protein processing.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20081216
Title: Dose-dependent inhibition of tobacco smoke carcinogen-induced lung tumorigenesis in A/J mice by indole-3-carbinol.
Journal: Cancer prevention research (Philadelphia, Pa.) 20081201
Title: BRCA1 transcriptional activity is enhanced by interactions between its AD1 domain and AhR.
Journal: Cancer chemotherapy and pharmacology 20081101
Title: Cancer chemotherapy with indole-3-carbinol, bis(3'-indolyl)methane and synthetic analogs.
Journal: Cancer letters 20081008
Title: Indole-3-carbinol prevents H(2)O(2)-induced inhibition of gap junctional intercellular communication by inactivation of PKB/Akt.
Journal: The Journal of veterinary medical science 20081001
Title: Synergistic action of dietary phyto-antioxidants on survival and proliferation of ovarian cancer cells.
Journal: Gynecologic oncology 20080901
Title: Aflatoxin B1 detoxification by CYP321A1 in Helicoverpa zea.
Journal: Archives of insect biochemistry and physiology 20080901
Title: Cancer is a preventable disease that requires major lifestyle changes.
Journal: Pharmaceutical research 20080901
Title: Mechanism of decreased susceptibility for Gram-negative bacteria and synergistic effect with ampicillin of indole-3-carbinol.
Journal: Biological & pharmaceutical bulletin 20080901
Title: Side-effects of cidofovir in the treatment of recurrent respiratory papillomatosis.
Journal: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20080801
Title: Indole-3-carbinol suppresses tumor-induced angiogenesis by inhibiting tube formation and inducing apoptosis.
Journal: Bioscience, biotechnology, and biochemistry 20080801
Title: Genomic profiling reveals an alternate mechanism for hepatic tumor promotion by perfluorooctanoic acid in rainbow trout.
Journal: Environmental health perspectives 20080801
Title: AH receptor agonist activity in human blood measured with a cell-based bioassay: evidence for naturally occurring AH receptor ligands in vivo.
Journal: Journal of exposure science & environmental epidemiology 20080701
Title: Inhibitory effects of a dietary phytochemical 3,3'-diindolylmethane on the phenobarbital-induced hepatic CYP mRNA expression and CYP-catalyzed reactions in female rats.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080701
Title: 5,5'-Dibromo-bis(3'-indolyl)methane induces Kruppel-like factor 4 and p21 in colon cancer cells.
Journal: Molecular cancer therapeutics 20080701
Title: Indole-3-carbinol-induced modulation of NF-kappaB signalling is breast cancer cell-specific and does not correlate with cell death.
Journal: Breast cancer research and treatment 20080601
Title: Identification of indole glucosinolate breakdown products with antifeedant effects on Myzus persicae (green peach aphid).
Journal: The Plant journal : for cell and molecular biology 20080601
Title: Putative mechanisms of action for indole-3-carbinol in the prevention of colorectal cancer.
Journal: Expert opinion on therapeutic targets 20080601
Title: 3,3'-Diindolylmethane stimulates murine immune function in vitro and in vivo.
Journal: The Journal of nutritional biochemistry 20080501
Title: Indole-3-carbinol enhances anti-proliferative, but not anti-invasive effects of oxaliplatin in colorectal cancer cell lines.
Journal: Biochemical pharmacology 20080501
Title: Indole-3-carbinol as a chemopreventive and anti-cancer agent.
Journal: Cancer letters 20080418
Title: A new medium-term rat colorectal bioassay applying neoplastic lesions as end points for detection of carcinogenesis modifiers effects with weak or controversial modifiers.
Journal: Toxicologic pathology 20080401
Title: Protective effects of isothiocyanates alone or in combination with vitamin C towards N-nitrosodibutylamine or N-nitrosopiperidine-induced oxidative DNA damage in the single-cell gel electrophoresis (SCGE)/HepG2 assay.
Journal: Journal of applied toxicology : JAT 20080301
Title: Indole-3-carbinol (I3C) exhibits inhibitory and preventive effects on prostate tumors in mice.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080301
Title: Indole-3-acetonitrile production from indole glucosinolates deters oviposition by Pieris rapae.
Journal: Plant physiology 20080301
Title: Chemopreventive agents modulate the protein expression profile of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone plus benzo[a]pyrene-induced lung tumors in A/J mice.
Journal: Carcinogenesis 20080301
Title: N-Alkoxy derivatization of indole-3-carbinol increases the efficacy of the G1 cell cycle arrest and of I3C-specific regulation of cell cycle gene transcription and activity in human breast cancer cells.
Journal: Biochemical pharmacology 20080201
Title: Recurrent respiratory papillomatosis: an overview of current thinking and treatment.
Journal: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20080201
Title: Screening of synthetic and plant-derived compounds for (anti)estrogenic and (anti)androgenic activities.
Journal: Analytical and bioanalytical chemistry 20080201
Title: Antiplatelet and antithrombotic activity of indole-3-carbinol in vitro and in vivo.
Journal: Phytotherapy research : PTR 20080101
Title: Renoprotective effects of neuronal NOS-derived nitric oxide and cyclooxygenase-2 metabolites in transgenic rats with inducible malignant hypertension.
Journal: American journal of physiology. Renal physiology 20080101
Title: Red clover isoflavones biochanin A and formononetin are potent ligands of the human aryl hydrocarbon receptor.
Journal: The Journal of steroid biochemistry and molecular biology 20080101
Title: Prorenin and glomerulosclerosis?
Journal: Journal of hypertension 20080101
Title: Dose-dependent titration of prorenin and blood pressure in Cyp1a1ren-2 transgenic rats: absence of prorenin-induced glomerulosclerosis.
Journal: Journal of hypertension 20080101
Title: Review. Indole-3-carbinol as a chemoprotective agent in breast and prostate cancer.
Journal: In vivo (Athens, Greece) 20080101
Title: TOR complex 2 is needed for cell cycle progression and anchorage-independent growth of MCF7 and PC3 tumor cells.
Journal: BMC cancer 20080101
Title: Selective androgen receptor modulators in preclinical and clinical development.
Journal: Nuclear receptor signaling 20080101
Title: Induction of cytotoxicity, apoptosis and cell cycle arrest by 1-t-butyl carbamoyl, 7-methyl-indole-3-ethyl isothiocyanate (NB7M) in nervous system cancer cells.
Journal: Drug design, development and therapy 20080101
Title: Recurrent Respiratory Papillomatosis (RRP)-Juvenile Onset.
Journal: Clinical medicine. Oncology 20080101
Title: Syzygium cumini inhibits growth and induces apoptosis in cervical cancer cell lines: a primary study.
Journal: Ecancermedicalscience 20080101
Title: Inhibition of amyloid fibrillation of lysozyme by indole derivatives--possible mechanism of action.
Journal: The FEBS journal 20071201
Title: Aldosterone receptor antagonism alleviates proteinuria, but not malignant hypertension, in Cyp1a1-Ren2 transgenic rats.
Journal: American journal of physiology. Renal physiology 20071101
Title: Extended treatment with physiologic concentrations of dietary phytochemicals results in altered gene expression, reduced growth, and apoptosis of cancer cells.
Journal: Molecular cancer therapeutics 20071101
Title: Inactivation of NF-kappaB by 3,3'-diindolylmethane contributes to increased apoptosis induced by chemotherapeutic agent in breast cancer cells.
Journal: Molecular cancer therapeutics 20071001
Title: In vitro antimicrobial activity and the mode of action of indole-3-carbinol against human pathogenic microorganisms.
Journal: Biological & pharmaceutical bulletin 20071001
Title: Short-term modulation of cell proliferation and apoptosis and preventive/therapeutic efficacy of various agents in a mammary cancer model.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070915
Title: Predicting the physiological relevance of in vitro cancer preventive activities of phytochemicals.
Journal: Acta pharmacologica Sinica 20070901
Title: A potent indole-3-carbinol derived antitumor agent with pleiotropic effects on multiple signaling pathways in prostate cancer cells.
Journal: Cancer research 20070815
Title: Indole-3-carbinol - induced growth inhibition can be converted to a cytotoxic response in the presence of TPA+Ca(2+) in squamous cell carcinoma cell lines.
Journal: FEBS letters 20070807
Title: Computer-aided rational drug design: a novel agent (SR13668) designed to mimic the unique anticancer mechanisms of dietary indole-3-carbinol to block Akt signaling.
Journal: Journal of medicinal chemistry 20070726
Title: Dietary phytochemicals regulate whole-body CYP1A1 expression through an arylhydrocarbon receptor nuclear translocator-dependent system in gut.
Journal: The Journal of clinical investigation 20070702
Title: Quantitative combination effects between sulforaphane and 3,3'-diindolylmethane on proliferation of human colon cancer cells in vitro.
Journal: Carcinogenesis 20070701
Title: Indole-3-carbinol inhibits 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone plus benzo(a)pyrene-induced lung tumorigenesis in A/J mice and modulates carcinogen-induced alterations in protein levels.
Journal: Cancer research 20070701
Title: Renal vascular and tubulointerstitial inflammation and proliferation in Cyp1a1-Ren2 transgenic rats with inducible ANG II-dependent malignant hypertension.
Journal: American journal of physiology. Renal physiology 20070601
Title: A review of the clinical efficacy and safety of cruciferous vegetable phytochemicals.
Journal: Nutrition reviews 20070601
Title: The candidacidal activity of indole-3-carbinol that binds with DNA.
Journal: IUBMB life 20070601
Title: Phytochemicals induce breast cancer resistance protein in Caco-2 cells and enhance the transport of benzo[a]pyrene-3-sulfate.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20070401
Title: Suppression of mammary gland carcinogenesis by post-initiation treatment of rats with tamoxifen or indole-3-carbinol or their combination.
Journal: European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20070401
Title: Allelochemical induction of cytochrome P450 monooxygenases and amelioration of xenobiotic toxicity in Helicoverpa zea.
Journal: Journal of chemical ecology 20070301
Title: Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis.
Journal: Pharmacological research 20070301
Title: Chemopreventive herbal anti-oxidants: current status and future perspectives.
Journal: Journal of clinical biochemistry and nutrition 20070301
Title: EGFR and Src are involved in indole-3-carbinol-induced death and cell cycle arrest of human breast cancer cells.
Journal: Carcinogenesis 20070201
Title: Lipid peroxidation, oxidative stress genes and dietary factors in breast cancer protection: a hypothesis.
Journal: Breast cancer research : BCR 20070101
Title: The effect of indole-3-carbinol on the expression of CYP1A1, CYP1B1 and AhR genes and proliferation of MCF-7 cells.
Journal: Acta biochimica Polonica 20070101
Title: Transposable elements are enriched within or in close proximity to xenobiotic-metabolizing cytochrome P450 genes.
Journal: BMC evolutionary biology 20070101
Title: Interplay of genes regulated by estrogen and diindolylmethane in breast cancer cell lines.
Journal: Molecular medicine (Cambridge, Mass.) 20070101
Title: Sensitive and robust gene expression changes in fish exposed to estrogen--a microarray approach.
Journal: BMC genomics 20070101
Title: 1,1-Bis(3'-indolyl)-1-(p-biphenyl)methane inhibits basal-like breast cancer growth in athymic nude mice.
Journal: Breast cancer research : BCR 20070101
Title: Gene expression profiling reveals effects of Cimicifuga racemosa (L.) NUTT. (black cohosh) on the estrogen receptor positive human breast cancer cell line MCF-7.
Journal: BMC pharmacology 20070101
Title: S100A7 (Psoriasin), highly expressed in ductal carcinoma in situ (DCIS), is regulated by IFN-gamma in mammary epithelial cells.
Journal: BMC cancer 20070101
Title: Putative cancer chemopreventive agents of dietary origin-how safe are they?
Journal: Nutrition and cancer 20070101
Title: Effects of prepubertal indole-3-carbinol treatment on development of N-methyl-N-nitrosourea-induced mammary carcinomas in female Sprague-Dawley rats.
Journal: In vivo (Athens, Greece) 20070101
Title: Abstracts of papers presented at the 2007 pittsburgh conference.
Journal: Journal of automated methods & management in chemistry 20070101
Title: Indole-3-carbinol mediated cell cycle arrest of LNCaP human prostate cancer cells requires the induced production of activated p53 tumor suppressor protein.
Journal: Biochemical pharmacology 20061215
Title: Indole-3-carbinol selectively uncouples expression and activity of estrogen receptor subtypes in human breast cancer cells.
Journal: Molecular endocrinology (Baltimore, Md.) 20061201
Title: AT1 receptor blockade is superior to conventional triple therapy in protecting against end-organ damage in Cyp1a1-Ren-2 transgenic rats with inducible hypertension.
Journal: Journal of hypertension 20061201
Title: Single-dose and multiple-dose administration of indole-3-carbinol to women: pharmacokinetics based on 3,3'-diindolylmethane.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20061201
Title: A bioisosteric approach to the discovery of indole carbinol androgen receptor ligands.
Journal: Bioorganic & medicinal chemistry letters 20061101
Title: Fas-mediated apoptosis in cholangiocarcinoma cells is enhanced by 3,3'-diindolylmethane through inhibition of AKT signaling and FLICE-like inhibitory protein.
Journal: The American journal of pathology 20061101
Title: Indole-3-carbinol enhances ultraviolet B-induced apoptosis by sensitizing human melanoma cells.
Journal: Cellular and molecular life sciences : CMLS 20061101
Title: Therapeutic intervention of experimental breast cancer bone metastasis by indole-3-carbinol in SCID-human mouse model.
Journal: Molecular cancer therapeutics 20061101
Title: Tumors from rats given 1,2-dimethylhydrazine plus chlorophyllin or indole-3-carbinol contain transcriptional changes in beta-catenin that are independent of beta-catenin mutation status.
Journal: Mutation research 20061010
Title: Estrogen receptor alpha as a target for indole-3-carbinol.
Journal: The Journal of nutritional biochemistry 20061001
Title: Brassica vegetable consumption reduces urinary F2-isoprostane levels independent of micronutrient intake.
Journal: Carcinogenesis 20061001
Title: Indole-3-carbinol in the maternal diet provides chemoprotection for the fetus against transplacental carcinogenesis by the polycyclic aromatic hydrocarbon dibenzo[a,l]pyrene.
Journal: Carcinogenesis 20061001
Title: Cyclooxygenase-2 inhibition normalizes arterial blood pressure in CYP1A1-REN2 transgenic rats with inducible ANG II-dependent malignant hypertension.
Journal: American journal of physiology. Renal physiology 20060901
Title: In vivo relevance of two critical levels for NAD(P)H:quinone oxidoreductase (NQO1)-mediated cellular protection against electrophile toxicity found in vitro.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20060801
Title: Indole-3-carbinol alters placental cytochrome P450 1A1 and P-glycoprotein levels in rats: a potential role in intensifying fetal intrauterine growth-retardation produced by tobacco smoke.
Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20060801
Title: Comparison of growth inhibition profiles and mechanisms of apoptosis induction in human colon cancer cell lines by isothiocyanates and indoles from Brassicaceae.
Journal: Mutation research 20060725
Title: Role of antioxidants in prophylaxis and therapy: A pharmaceutical perspective.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20060720
Title: British Association of Paediatric Otorhinolaryngology members experience with recurrent respiratory papillomatosis.
Journal: International journal of pediatric otorhinolaryngology 20060701
Title: Profiling the hepatic effects of flutamide in rats: a microarray comparison with classical aryl hydrocarbon receptor ligands and atypical CYP1A inducers.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20060701
Title: Genetic clamping of renin gene expression induces hypertension and elevation of intrarenal Ang II levels of graded severity in Cyp1a1-Ren2 transgenic rats.
Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20060601
Title: 3,3'-diindolylmethane and paclitaxel act synergistically to promote apoptosis in HER2/Neu human breast cancer cells.
Journal: The Journal of surgical research 20060515
Title: Molecular targets of dietary agents for prevention and therapy of cancer.
Journal: Biochemical pharmacology 20060514
Title: Indole-3-carbinol-induced death in cancer cells involves EGFR downregulation and is exacerbated in a 3D environment.
Journal: Apoptosis : an international journal on programmed cell death 20060501
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Gene expression profiling revealed survivin as a target of 3,3'-diindolylmethane-induced cell growth inhibition and apoptosis in breast cancer cells.
Journal: Cancer research 20060501
Title: Ultraviolet radiation-induced non-melanoma skin cancer in the Crl:SKH1:hr-BR hairless mouse: augmentation of tumor multiplicity by chlorophyllin and protection by indole-3-carbinol.
Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20060501
Title: Inhibition of amyloid fibril formation and cytotoxicity by hydroxyindole derivatives.
Journal: Biochemistry 20060418
Title: Synthetic dimer of indole-3-carbinol: second generation diet derived anti-cancer agent in hormone sensitive prostate cancer.
Journal: The Prostate 20060401
Title: Indole-3-carbinol, but not its major digestive product 3,3'-diindolylmethane, induces reversible hepatocyte hypertrophy and cytochromes P450.
Journal: Toxicology and applied pharmacology 20060301
Title: Toxicogenomic profiling of the hepatic tumor promoters indole-3-carbinol, 17beta-estradiol and beta-naphthoflavone in rainbow trout.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20060301
Title: Using salmonid microarrays to understand the dietary modulation of carcinogenesis in rainbow trout.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20060301
Title: Fate of 3,3'-diindolylmethane in cultured MCF-7 human breast cancer cells.
Journal: Chemical research in toxicology 20060301
Title: Multiple, disparate roles for calcium signaling in apoptosis of human prostate and cervical cancer cells exposed to diindolylmethane.
Journal: Molecular cancer therapeutics 20060301
Title: Indole-3-carbinol activates the ATM signaling pathway independent of DNA damage to stabilize p53 and induce G1 arrest of human mammary epithelial cells.
Journal: International journal of cancer 20060215
Title: BRCA1 and BRCA2 as molecular targets for phytochemicals indole-3-carbinol and genistein in breast and prostate cancer cells.
Journal: British journal of cancer 20060213
Title: 3,3'-Diindolylmethane downregulates pro-survival pathway in hormone independent prostate cancer.
Journal: Biochemical and biophysical research communications 20060210
Title: Effects of indole-3-carbinol and phenethyl isothiocyanate on colon carcinogenesis induced by azoxymethane in rats.
Journal: Carcinogenesis 20060201
Title: Post-initiation chlorophyllin exposure does not modulate aflatoxin-induced foci in the liver and colon of rats.
Journal: Journal of carcinogenesis 20060101
Title: Growth of a human mammary tumor cell line is blocked by galangin, a naturally occurring bioflavonoid, and is accompanied by down-regulation of cyclins D3, E, and A.
Journal: Breast cancer research : BCR 20060101
Title: The natural chemopreventive compound indole-3-carbinol: state of the science.
Journal: In vivo (Athens, Greece) 20060101
Title: A randomized phase II trial of indole-3-carbinol in the treatment of vulvar intraepithelial neoplasia.
Journal: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20060101
Title: A zebrafish assay for identifying neuroprotectants in vivo.
Journal: Neurotoxicology and teratology 20060101
Title: Protective effects of isothiocyanates towards N-nitrosamine-induced DNA damage in the single-cell gel electrophoresis (SCGE)/HepG2 assay.
Journal: Journal of applied toxicology : JAT 20060101
Title: Transcriptome profiling of human hepatocytes treated with Aroclor 1254 reveals transcription factor regulatory networks and clusters of regulated genes.
Journal: BMC genomics 20060101
Title: Protective effects of isothiocyanates towards N-nitrosamine-induced DNA damage in the single-cell gel electrophoresis (SCGE)/HepG2 assay.
Journal: Journal of applied toxicology : JAT 20060101
Title: Modulation of apoptosis by cancer chemopreventive agents.
Journal: Mutation research 20051211
Title: Enhanced tubuloglomerular feedback in Cyp1a1-Ren2 transgenic rats with inducible ANG II-dependent malignant hypertension.
Journal: American journal of physiology. Renal physiology 20051201
Title: Recurrent respiratory papillomatosis: pathogenesis to treatment.
Journal: Current opinion in otolaryngology & head and neck surgery 20051201
Title: Nutrition and primary prevention of breast cancer: foods, nutrients and breast cancer risk.
Journal: European journal of obstetrics, gynecology, and reproductive biology 20051201
Title: Inhibition of phosphatidylinositol 3-kinase/protein kinase B signaling is not sufficient to account for indole-3-carbinol-induced apoptosis in some breast and prostate tumor cells.
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Title: Induction of phase-1 metabolizing enzymes by oltipraz, flavone and indole-3-carbinol enhance the formation and transport of benzo[a]pyrene sulfate conjugates in intestinal Caco-2 cells.
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Title: Indole-3-carbinol suppresses NF-kappaB and IkappaBalpha kinase activation, causing inhibition of expression of NF-kappaB-regulated antiapoptotic and metastatic gene products and enhancement of apoptosis in myeloid and leukemia cells.
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Title: Inhibition of cell proliferation and in vitro markers of angiogenesis by indole-3-carbinol, a major indole metabolite present in cruciferous vegetables.
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Title: Prior exposure to indole-3-carbinol decreases the incidence of specific cyclophosphamide-induced developmental defects in mice.
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Title: Effects of analogs of indole-3-carbinol cyclic trimerization product in human breast cancer cells.
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Title: Salt-sensitive hypertension develops after transient induction of ANG II-dependent hypertension in Cyp1a1-Ren2 transgenic rats.
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Title: 3,3'-Diindolylmethane inhibits angiogenesis and the growth of transplantable human breast carcinoma in athymic mice.
Journal: Carcinogenesis 20050401
Title: Differential expression and stability of endogenous nuclear factor E2-related factor 2 (Nrf2) by natural chemopreventive compounds in HepG2 human hepatoma cells.
Journal: Journal of biochemistry and molecular biology 20050331
Title: Indole-3-carbinol (I3C) inhibits cyclin-dependent kinase-2 function in human breast cancer cells by regulating the size distribution, associated cyclin E forms, and subcellular localization of the CDK2 protein complex.
Journal: The Journal of biological chemistry 20050311
Title: Indole-3-carbinol and 3,3'-diindolylmethane induce expression of NAG-1 in a p53-independent manner.
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Title: Effects of dietary chemopreventive phytochemicals on P-glycoprotein function.
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Title: Successful use of intralesional and intravenous cidofovir in association with indole-3-carbinol in an 8-year-old girl with pulmonary papillomatosis.
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Title: Modulation of P-glycoprotein-mediated multidrug resistance in K562 leukemic cells by indole-3-carbinol.
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Title: Targets for indole-3-carbinol in cancer prevention.
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Title: Characterization of the N-methoxyindole-3-carbinol (NI3C)--induced cell cycle arrest in human colon cancer cell lines.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20050101
Title: Selective growth regulatory and pro-apoptotic effects of DIM is mediated by AKT and NF-kappaB pathways in prostate cancer cells.
Journal: Frontiers in bioscience : a journal and virtual library 20050101
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Journal: Oncology reports 20050101
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Journal: Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 20050101
Title: Red maca (Lepidium meyenii) reduced prostate size in rats.
Journal: Reproductive biology and endocrinology : RB&E 20050101
Title: Inhibition of nuclear translocation of nuclear factor-{kappa}B contributes to 3,3'-diindolylmethane-induced apoptosis in breast cancer cells.
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Title: Indole-3-carbinol prevents PTEN loss in cervical cancer in vivo.
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Title: Dietary indole-3-carbinol promotes endometrial adenocarcinoma development in rats initiated with N-ethyl-N'-nitro-N-nitrosoguanidine, with induction of cytochrome P450s in the liver and consequent modulation of estrogen metabolism.
Journal: Carcinogenesis 20041101
Title: Dietary agent indole-3-carbinol protects female rats against the hepatotoxicity of the antitumor drug ET-743 (trabectidin) without compromising efficacy in a rat mammary carcinoma.
Journal: International journal of cancer 20041010
Title: Indole-3-carbinol activates the cyclin-dependent kinase inhibitor p15(INK4b) gene.
Journal: FEBS letters 20041008
Title: Induction of apoptosis in human prostate cancer cell line, PC3, by 3,3'-diindolylmethane through the mitochondrial pathway.
Journal: British journal of cancer 20041004
Title: Induction of apoptosis in a non-small cell human lung cancer cell line by isothiocyanates is associated with P53 and P21.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20041001
Title: Current status of antiviral therapy for juvenile-onset recurrent respiratory papillomatosis.
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Title: An antagonist of retinoic acid receptors more effectively inhibits growth of human prostate cancer cells than normal prostate epithelium.
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Title: Pharmacokinetics and tissue disposition of indole-3-carbinol and its acid condensation products after oral administration to mice.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20040801
Title: Indole-3-carbinol stimulates transcription of the interferon gamma receptor 1 gene and augments interferon responsiveness in human breast cancer cells.
Journal: Carcinogenesis 20040701
Title: Crambene, a bioactive nitrile derived from glucosinolate hydrolysis, acts via the antioxidant response element to upregulate quinone reductase alone or synergistically with indole-3-carbinol.
Journal: Toxicology and applied pharmacology 20040701
Title: Effects of cruciferous vegetable consumption on urinary metabolites of the tobacco-specific lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in singapore chinese.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20040601
Title: Indole-3-carbinol for recurrent respiratory papillomatosis: long-term results.
Journal: Journal of voice : official journal of the Voice Foundation 20040601
Title: Inhibition of MUC1 expression by indole-3-carbinol.
Journal: International journal of cancer 20040510
Title: Protective effects of indole-3-carbinol on cyclophosphamide-induced clastogenecity in mouse bone marrow cells.
Journal: Human & experimental toxicology 20040501
Title: Cruciferous vegetables: cancer protective mechanisms of glucosinolate hydrolysis products and selenium.
Journal: Integrative cancer therapies 20040301
Title: Lack of an inducible effect of dietary soy isoflavones on the mRNA abundance of hepatic cytochrome P-450 isozymes in rats.
Journal: Bioscience, biotechnology, and biochemistry 20040301
Title: Endogenous and dietary indoles: a class of antioxidants and radical scavengers in the ABTS assay.
Journal: Free radical research 20040301
Title: Endoplasmic reticulum stress as a correlate of cytotoxicity in human tumor cells exposed to diindolylmethane in vitro.
Journal: Cell stress & chaperones 20040301
Title: Established and potential strategies against papillomavirus infections.
Journal: The Journal of antimicrobial chemotherapy 20040201
Title: Modulation of the constitutive activated STAT3 transcription factor in pancreatic cancer prevention: effects of indole-3-carbinol (I3C) and genistein.
Journal: Anticancer research 20040101
Title: Differences in the hepatic P450-dependent metabolism of estrogen and tamoxifen in response to treatment of rats with 3,3'-diindolylmethane and its parent compound indole-3-carbinol.
Journal: Cancer detection and prevention 20040101
Title: Effects of dietary anticarcinogens and nonsteroidal anti-inflammatory drugs on rat gastrointestinal UDP-glucuronosyltransferases.
Journal: Anticancer research 20040101
Title: Inactivation of akt and NF-kappaB play important roles during indole-3-carbinol-induced apoptosis in breast cancer cells.
Journal: Nutrition and cancer 20040101
Title: Prevention and repair of DNA damage by selected phytochemicals as measured by single cell gel electrophoresis.
Journal: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20040101
Title: Apoptosis in cervical cancer cells: implications for adjunct anti-estrogen therapy for cervical cancer.
Journal: Anticancer research 20040101
Title: Chemopreventive effect of indole-3-carbinol on induction of preneoplastic altered hepatic foci.
Journal: Nutrition and cancer 20040101
Title: Indole-3-carbinol induces a G1 cell cycle arrest and inhibits prostate-specific antigen production in human LNCaP prostate carcinoma cells.
Journal: Cancer 20031201
Title: Broccoli compound inhibits HSV.
Journal: AIDS patient care and STDs 20031101
Title: A selective irreversible inhibitor targeting a PDZ protein interaction domain.
Journal: Journal of the American Chemical Society 20031008
Title: Ingestion of a dietary supplement containing dehydroepiandrosterone (DHEA) and androstenedione has minimal effect on immune function in middle-aged men.
Journal: Journal of the American College of Nutrition 20031001
Title: Chemoprevention of gastrointestinal malignancies.
Journal: ANZ journal of surgery 20030901
Title: The disposition and metabolism of 2-amino-3-methylimidazo-[4,5-f]quinoline in the F344 rat at high versus low doses of indole-3-carbinol.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20030801
Title: Arsenate reduction in human erythrocytes and rats--testing the role of purine nucleoside phosphorylase.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20030701
Title: Evaluation of chronic dietary exposure to indole-3-carbinol and absorption-enhanced 3,3'-diindolylmethane in sprague-dawley rats.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20030701
Title: Plant-derived 3,3'-Diindolylmethane is a strong androgen antagonist in human prostate cancer cells.
Journal: The Journal of biological chemistry 20030606
Title: Pretreatment of indole-3-carbinol augments TRAIL-induced apoptosis in a prostate cancer cell line, LNCaP.
Journal: FEBS letters 20030605
Title: Indole-3-carbinol and 3,3'-diindolylmethane induce apoptosis in human prostate cancer cells.
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Title: Phase II in vitro metabolism of 3-methylindole metabolites in porcine liver.
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Title: Cervical dysplasia: early intervention.
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Title: Liquid chromatographic assay for the simultaneous determination of indole-3-carbinol and its acid condensation products in plasma.
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Title: Mutational analysis of Ctnnb1 and Apc in tumors from rats given 1,2-dimethylhydrazine or 2-amino-3-methylimidazo[4,5-f]quinoline: mutational 'hotspots' and the relative expression of beta-catenin and c-jun.
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Title: The effect of indole-3-carbinol and sulforaphane on a prostate cancer cell line.
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Journal: The Journal of organic chemistry 20030110
Title: Growth-inhibitory effects of the chemopreventive agent indole-3-carbinol are increased in combination with the polyamine putrescine in the SW480 colon tumour cell line.
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Title: The rainbow trout (Oncorhynchus mykiss) tumor model: recent applications in low-dose exposures to tumor initiators and promoters.
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Title: Indole-3-carbinol (I3C) induces apoptosis in tumorigenic but not in nontumorigenic breast epithelial cells.
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Title: Effects of treatment of rats with indole-3-carbinol on apoptosis in the mammary gland and mammary adenocarcinomas.
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Title: Role of salicylic acid in systemic resistance induced by Pseudomonas fluorescens against Fusarium oxysporum f. sp. ciceri in chickpea.
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Title: Comparative molecular field analysis of substrates for an aryl sulfotransferase based on catalytic mechanism and protein homology modeling.
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Title: Differential effects of vegetable-derived indoles on the induction of quinone reductase in hepatoma cells.
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Title: Plant-derived biomolecules in fermented cabbage.
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Title: Development of a multi-organ rat model for evaluating chemopreventive agents: efficacy of indole-3-carbinol-. Certain health supplements may cause both carcinogenic and anticarcinogenic effects.
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Title: Endocrine disruption by indole-3-carbinol and tamoxifen: blockage of ovulation.
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Title: Pharmacotherapy of recurrent respiratory papillomatosis.
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Title: Akt inactivation is a key event in indole-3-carbinol-induced apoptosis in PC-3 cells.
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Title: Estrogen metabolism and the diet-cancer connection: rationale for assessing the ratio of urinary hydroxylated estrogen metabolites.
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Title: The 19th International Papillomavirus Conference.
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Title: Development of a multi-organ rat model for evaluating chemopreventive agents: efficacy of indole-3-carbinol.
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Title: Steroid hormone mimics: molecular mechanisms of cell growth and apoptosis in normal and malignant mammary epithelial cells.
Journal: The Journal of steroid biochemistry and molecular biology 20020201
Title: Organ distribution of multidrug resistance proteins 1, 2, and 3 (Mrp1, 2, and 3) mRNA and hepatic induction of Mrp3 by constitutive androstane receptor activators in rats.
Journal: The Journal of pharmacology and experimental therapeutics 20020101
Title: Induction profile of rat organic anion transporting polypeptide 2 (oatp2) by prototypical drug-metabolizing enzyme inducers that activate gene expression through ligand-activated transcription factor pathways.
Journal: The Journal of pharmacology and experimental therapeutics 20020101
Title: Lack of chemoprevention of indole-3-carbinol in N-methyl-N-nitrosourea-induced mammary carcinogenesis in rats.
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Title: Anti-metastatic activities of all-trans retinoic acid, indole-3-carbinol and (+)-catechin in Dunning rat invasive prostate adenocarcinoma cells.
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Title: A high-throughput cell-based reporter gene system for measurement of CYP1A1 induction.
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Title: Transplacental exposure to indole-3-carbinol induces sex-specific expression of CYP1A1 and CYP1B1 in the liver of Fischer 344 neonatal rats.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20011201
Title: Prevention and treatment of cancer with indole-3-carbinol.
Journal: Alternative medicine review : a journal of clinical therapeutic 20011201
Title: Cytostatic effects of 3,3'-diindolylmethane in human endometrial cancer cells result from an estrogen receptor-mediated increase in transforming growth factor-alpha expression.
Journal: Carcinogenesis 20011101
Title: Controlled hypertension, a transgenic toggle switch reveals differential mechanisms underlying vascular disease.
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Title: Cell proliferation in cancer prevention; effects of preventive agents on estrogen-related endometrial carcinogenesis model and on an in vitro model in human colorectal cells.
Journal: Mutation research 20010901
Title: Effects of androstenedione-herbal supplementation on serum sex hormone concentrations in 30- to 59-year-old men.
Journal: International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20010901
Title: Post-initiation treatment of Indole-3-carbinol did not suppress N-methyl-N-nitrosourea induced mammary carcinogenesis in rats.
Journal: Cancer letters 20010828
Title: Dietary indoles and isothiocyanates that are generated from cruciferous vegetables can both stimulate apoptosis and confer protection against DNA damage in human colon cell lines.
Journal: Cancer research 20010815
Title: Cytochrome P4502E1 induction increases thioacetamide liver injury in diet-restricted rats.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20010801
Title: Indole-3-carbinol modulation of hepatic monooxygenases CYP1A1, CYP1A2 and FMO1 in guinea pig, mouse and rabbit.
Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20010801
Title: Detection and characterization of DNA adducts of 3-methylindole.
Journal: Chemical research in toxicology 20010801
Title: The synergistic upregulation of phase II detoxification enzymes by glucosinolate breakdown products in cruciferous vegetables.
Journal: Toxicology and applied pharmacology 20010715
Title: Selective dehydrogenation/oxygenation of 3-methylindole by cytochrome p450 enzymes.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20010701
Title: Indole-3-carbinol inhibits CDK6 expression in human MCF-7 breast cancer cells by disrupting Sp1 transcription factor interactions with a composite element in the CDK6 gene promoter.
Journal: The Journal of biological chemistry 20010622
Title: Oxidations of 17beta-estradiol and estrone and their interconversions catalyzed by liver, mammary gland and mammary tumor after acute and chronic treatment of rats with indole-3-carbinol or beta-naphthoflavone.
Journal: Canadian journal of physiology and pharmacology 20010601
Title: Risk reduction for DDT toxicity and carcinogenesis through dietary modification.
Journal: The journal of the Royal Society for the Promotion of Health 20010601
Title: Effect of nutritional indoles on activity of xenobiotic metabolism enzymes and T-2 toxicity in rats.
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Title: Indole-3-carbinol (I3C) induced cell growth inhibition, G1 cell cycle arrest and apoptosis in prostate cancer cells.
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Title: 2,3,7,8-Tetrachlorodibenzo-p-dioxin and diindolylmethanes differentially induce cytochrome P450 1A1, 1B1, and 19 in H295R human adrenocortical carcinoma cells.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20010501
Title: The Cap'n'Collar basic leucine zipper transcription factor Nrf2 (NF-E2 p45-related factor 2) controls both constitutive and inducible expression of intestinal detoxification and glutathione biosynthetic enzymes.
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Title: Effects of indole-3-carbinol on immune responses, aberrant crypt foci, and colonic crypt cell proliferation in rats.
Journal: Journal of toxicology and environmental health. Part A 20010406
Title: Molecular biology of the Ah receptor and its role in carcinogenesis.
Journal: Toxicology letters 20010331
Title: Methyl-substituted diindolylmethanes as inhibitors of estrogen-induced growth of T47D cells and mammary tumors in rats.
Journal: Breast cancer research and treatment 20010301
Title: 3,3'-diindolylmethane, a major condensation product of indole-3-carbinol, is a potent estrogen in the rainbow trout.
Journal: Toxicology and applied pharmacology 20010201
Title: Post-initiation effects of chlorophyllin and indole-3-carbinol in rats given 1,2-dimethylhydrazine or 2-amino-3-methyl- imidazo.
Journal: Carcinogenesis 20010201
Title: beta-Catenin mutation in rat colon tumors initiated by 1,2-dimethylhydrazine and 2-amino-3-methylimidazo[4,5-f]quinoline, and the effect of post-initiation treatment with chlorophyllin and indole-3-carbinol.
Journal: Carcinogenesis 20010201
Title: Three different stable human breast adenocarcinoma sublines that overexpress ALDH3A1 and certain other enzymes, apparently as a consequence of constitutively upregulated gene transcription mediated by transactivated EpREs (electrophile responsive elements) present in the 5'-upstream regions of these genes.
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Title: Oestrogen and progesterone increase the levels of apoptosis induced by the human papillomavirus type 16 E2 and E7 proteins.
Journal: The Journal of general virology 20010101
Title: Application of the ethoxyresorufin-O-deethylase (EROD) assay to mixtures of halogenated aromatic compounds.
Journal: Environmental toxicology 20010101
Title: Effects of binary mixtures of six xenobiotics on hormone concentrations and morphometric endpoints of northern bobwhite quail (Colinus virginianus).
Journal: Chemosphere 20010101
Title: Unsymmetrical methylene derivatives of indoles as antiproliferative agents.
Journal: European journal of medicinal chemistry 20010101
Title: Concurrent flavin-containing monooxygenase down regulation and cytochrome P450 induction by dietary indoles in the rat: implication for drug-drug interactions.
Journal: Advances in experimental medicine and biology 20010101
Title: Indole-3-carbinol in women with SLE: effect on estrogen metabolism and disease activity.
Journal: Lupus 20010101
Title: Comparative tissue-specific toxicities of 20 cancer preventive agents using cultured cells from 8 different normal human epithelia.
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Title: Cruciferous vegetables and cancer prevention.
Journal: Nutrition and cancer 20010101
Title: Abrogation of estrogen-mediated cellular and biochemical effects by indole-3-carbinol.
Journal: Nutrition and cancer 20010101
Title: Quantitative determination of 3,3'-diindolylmethane in urine of individuals receiving indole-3-carbinol.
Journal: Nutrition and cancer 20010101
Title: Indole-3-carbinol is a negative regulator of estrogen receptor-alpha signaling in human tumor cells.
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Title: Chemoprevention of aflatoxin B1-induced carcinogenesis by indole-3-carbinol in rat liver--predicting the outcome using early biomarkers.
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Title: Signal transduction-mediated activation of the aryl hydrocarbon receptor in rat hepatoma H4IIE cells.
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Title: Mechanism of action of dietary chemoprotective agents in rat liver: induction of phase I and II drug metabolizing enzymes and aflatoxin B1 metabolism.
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