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112137-89-0,MFCD00869984
Catalog No.:AA008RHA

112137-89-0 | (+/-)-15-DEOXY-[16RS]-16-HYDROXY-16-METHYLPROSTAGLANDIN E1

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Purity
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1mg
≥97%
in stock  
$80.00   $56.00
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5mg
≥97%
in stock  
$356.00   $249.00
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10mg
≥97%
in stock  
$670.00   $469.00
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50mg
≥97%
in stock  
$2,358.00   $1,650.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA008RHA
Chemical Name:
(+/-)-15-DEOXY-[16RS]-16-HYDROXY-16-METHYLPROSTAGLANDIN E1
CAS Number:
112137-89-0
Molecular Formula:
C21H36O5
Molecular Weight:
368.5075
MDL Number:
MFCD00869984
SMILES:
CCCCC(CC=CC1C(O)CC(=O)C1CCCCCCC(=O)O)(O)C
Properties
Computed Properties
 
Complexity:
473  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
3  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
13  
Undefined Atom Stereocenter Count:
1  
XLogP3:
3.3  

Downstream Synthesis Route

[1]CurrentPatentAssignee:YOOOOKJOON;LIFEXBIOLABS-US2021/139435,2021,A1Locationinpatent:Paragraph0171-0173

[1]CurrentPatentAssignee:YOOOOKJOON;LIFEXBIOLABS-US2021/139435,2021,A1Locationinpatent:Paragraph0147-0149

Literature

Title: Validated method for the determination of misoprostol acid in whole blood by ultra performance liquid chromatography-tandem mass spectrometry.

Journal: Journal of pharmaceutical and biomedical analysis 20121201

Title: Effect of bacterial vaginosis on the pharmacokinetics of misoprostol in early pregnancy.

Journal: Human reproduction (Oxford, England) 20120201

Title: Development and validation of highly sensitive method for determination of misoprostol free acid in human plasma by liquid chromatography-electrospray ionization tandem mass spectrometry: application to a clinical pharmacokinetic study.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110915

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Pharmacokinetics of repeated doses of misoprostol.

Journal: Human reproduction (Oxford, England) 20090801

Title: Pharmacokinetic profiles up to 12 h after administration of vaginal, sublingual and slow-release oral misoprostol.

Journal: Human reproduction (Oxford, England) 20070701

Title: Determination of misoprostol acid in human plasma by liquid chromatography coupled to tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070601

Title: The pharmacokinetics of the prostaglandin E1 analogue misoprostol in plasma and colostrum after postpartum oral administration.

Journal: European journal of obstetrics, gynecology, and reproductive biology 20030501

Title: The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs.

Journal: Biochimica et biophysica acta 20000117

Title: Vijaya Bharathi D, et al. Development and validation of highly sensitive method for determination of misoprostol free acid in human plasma by liquid chromatography-electrospray ionization tandem mass spectrometry: application to a clinical pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Sep 15;879(26):2827-33.

Title: Schmidt-Hansen M, et al. Simultaneous compared to interval administration of mifepristone and misoprostol for medical abortion up to 10+0 weeks' gestation: a systematic review with meta-analyses. BMJ Sex Reprod Health. 2020 Feb 20. pii: bmjsrh-2019-200448.

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SDS
Tags:112137-89-0 Molecular Formula|112137-89-0 MDL|112137-89-0 SMILES|112137-89-0 (+/-)-15-DEOXY-[16RS]-16-HYDROXY-16-METHYLPROSTAGLANDIN E1