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829-74-3,MFCD00008080
Catalog No.:AA00G384

829-74-3 | 4-(2-Amino-1-hydroxypropyl)benzene-1,2-diol

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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00G384
Chemical Name:
4-(2-Amino-1-hydroxypropyl)benzene-1,2-diol
CAS Number:
829-74-3
Molecular Formula:
C9H13NO3
Molecular Weight:
183.2044
MDL Number:
MFCD00008080
SMILES:
C[C@@H]([C@@H](c1ccc(c(c1)O)O)O)N
NSC Number:
757084
Properties
Computed Properties
 
Complexity:
165  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
2  
XLogP3:
-0.8  

Literature

Title: QM/MM studies on the catalytic mechanism of phenylethanolamine N-methyltransferase.

Journal: Biochimica et biophysica acta 20120401

Title: An emphasis on the wide usage and important role of local anesthesia in dentistry: A strategic review.

Journal: Dental research journal 20120101

Title: Abnormal plasma monoamine metabolism in schizophrenia and its correlation with clinical responses to risperidone treatment.

Journal: Psychiatry research 20110730

Title: Oral manifestations of thyroid disorders and its management.

Journal: Indian journal of endocrinology and metabolism 20110701

Title: Injection technique and local anesthetic agent selection.

Journal: Texas dental journal 20110101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Beta-adrenergic blocking agents and dental vasoconstrictors.

Journal: Dental clinics of North America 20101001

Title: A prospective, randomized, double-blind comparison of 2% mepivacaine with 1 : 20,000 levonordefrin versus 2% lidocaine with 1 : 100,000 epinephrine for maxillary infiltrations.

Journal: Anesthesia progress 20100101

Title: Absence of nigral degeneration in aged parkin/DJ-1/PINK1 triple knockout mice.

Journal: Journal of neurochemistry 20091101

Title: Parkinson disease: systemic and orofacial manifestations, medical and dental management.

Journal: Journal of the American Dental Association (1939) 20090601

Title: Gestational hypoxia alone or combined with restraint sensitizes the hypothalamic-pituitary-adrenal axis and induces anxiety-like behavior in adult male rat offspring.

Journal: Neuroscience 20090410

Title: Involvement of central alpha1-adrenoceptors on renal responses to central moxonidine and alpha-methylnoradrenaline.

Journal: European journal of pharmacology 20090401

Title: Urine levels of catecholamines in Greek children with obstructive sleep-disordered breathing.

Journal: Pediatric pulmonology 20090101

Title: [Effects of various neuromediators and regulatory peptides on the impulse activity of neurons in the lateral vestibular nucleus].

Journal: Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine 20090101

Title: Estimates of serotonin and norepinephrine transporter inhibition in depressed patients treated with paroxetine or venlafaxine.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20081201

Title: Reversal of soft-tissue local anesthesia with phentolamine mesylate in adolescents and adults.

Journal: Journal of the American Dental Association (1939) 20080801

Title: Attenuation of autonomic nervous system functions in hypertensive patients at rest and during orthostatic stimulation.

Journal: Journal of clinical hypertension (Greenwich, Conn.) 20080201

Title: Direct evidence for imidazoline (I1) receptor modulation of ethanol action on norepinephrine-containing neurons in the rostral ventrolateral medulla in conscious spontaneously hypertensive rats.

Journal: Alcoholism, clinical and experimental research 20070401

Title: Why and what type of vasoconstrictors are added to local anaesthetic solutions?

Journal: SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging 20060601

Title: Neurohumoral activation as a link to systemic manifestations of chronic lung disease.

Journal: Chest 20051101

Title: Neuronal norepinephrine responses of the rostral ventrolateral medulla and nucleus tractus solitarius neurons distinguish the I1- from the alpha2-receptor-mediated hypotension in conscious SHRs.

Journal: Journal of cardiovascular pharmacology 20050701

Title: Comparative evaluation of positron emission tomography radiotracers for imaging the norepinephrine transporter: (S,S) and (R,R) enantiomers of reboxetine analogs ([11C]methylreboxetine, 3-Cl-[11C]methylreboxetine and [18F]fluororeboxetine), (R)-[11C]nisoxetine, [11C]oxaprotiline and [11C]lortalamine.

Journal: Journal of neurochemistry 20050701

Title: The Leu7Pro polymorphism of preproNPY is associated with decreased insulin secretion, delayed ghrelin suppression, and increased cardiovascular responsiveness to norepinephrine during oral glucose tolerance test.

Journal: The Journal of clinical endocrinology and metabolism 20050601

Title: Site-dependent inhibition of neuronal c-jun in the brainstem elicited by imidazoline I1 receptor activation: role in rilmenidine-evoked hypotension.

Journal: European journal of pharmacology 20050509

Title: Is hormonal activation during exercise useful for risk stratification in patients with moderate congestive heart failure?

Journal: American heart journal 20040801

Title: Lateralization in autonomic dysfunction in ischemic stroke involving the insular cortex.

Journal: Neuroreport 20040209

Title: Postnatal weight gain inhibition does not account for neurobehavioral consequences of neonatal Borna disease virus infection.

Journal: Physiology & behavior 20031101

Title: Serum mepivacaine concentrations after intraoral injection in young children.

Journal: Journal of the California Dental Association 20031001

Title: A comparison of alpha-methylnorepinephrine, vasopressin and epinephrine for cardiac resuscitation.

Journal: Resuscitation 20030401

Title: Myocardial dysfunction and male mortality in peroxisome proliferator-activated receptor alpha knockout mice overexpressing lipoprotein lipase in muscle.

Journal: Laboratory investigation; a journal of technical methods and pathology 20030201

Title: Nitric oxide discriminates the sites and mechanisms of action of centrally acting anti-hypertensive drugs in rabbits.

Journal: Neuropharmacology 20021201

Title: Short exposure of maturing, bone marrow-derived dendritic cells to norepinephrine: impact on kinetics of cytokine production and Th development.

Journal: Journal of neuroimmunology 20020801

Title: A selective alpha(2)-adrenergic agonist for cardiac resuscitation.

Journal: The Journal of laboratory and clinical medicine 20020701

Title: [Further study on the indexes of auxiliary laboratory diagnosis in the syndrome of hyperactivity of liver-yang].

Journal: Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University 20020628

Title: Evidence for synergy between alpha(2)-adrenergic and nonadrenergic mechanisms in central blood pressure regulation.

Journal: Circulation 20020305

Title: Age-related changes in adrenergic neuroeffector transmission.

Journal: Autonomic neuroscience : basic & clinical 20020227

Title: Effects of central imidazolinergic and alpha2-adrenergic activation on water intake.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20010901

Title: Haemodynamic characterization of young normotensive men carrying the 825T-allele of the G-protein beta3 subunit.

Journal: Pharmacogenetics 20010801

Title: Cardiac remodeling and contractile function in acid alpha-glucosidase knockout mice.

Journal: Physiological genomics 20010427

Title: [Acute polyradiculoneuritis and dysautonomia: contribution of assaying catecholamines and their methoxylated metabolites].

Journal: Revue neurologique 20010301

Title: alpha-Methylnorepinephrine, a selective alpha2-adrenergic agonist for cardiac resuscitation.

Journal: Journal of the American College of Cardiology 20010301

Title: Nitric oxide and central antihypertensive drugs: one more difference between catecholamines and imidazolines.

Journal: Hypertension (Dallas, Tex. : 1979) 20010201

Title: Comprehensive local muscle training increases aerobic working capacity and quality of life and decreases neurohormonal activation in patients with chronic heart failure.

Journal: European journal of heart failure 20010101

Title: Selectivity of agonists for cloned alpha 1-adrenergic receptor subtypes.

Journal: Molecular pharmacology 19941101

Title: Hypertensive response to levonordefrin in a patient receiving propranolol: report of case.

Journal: Journal of the American Dental Association (1939) 19880101

Title: Accelerated hypertension complicated by myocardial infarction after use of a local anesthetic/vasoconstrictor preparation.

Journal: American heart journal 19870901

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Tags:829-74-3 Molecular Formula|829-74-3 MDL|829-74-3 SMILES|829-74-3 4-(2-Amino-1-hydroxypropyl)benzene-1,2-diol