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848344-36-5,MFCD08272350
Catalog No.:AA00G3KR

848344-36-5 | AS-602801

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$17.00   $12.00
- +
5mg
98%
in stock  
$43.00   $30.00
- +
10mg
98%
in stock  
$64.00   $45.00
- +
25mg
98%
in stock  
$107.00   $75.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00G3KR
Chemical Name:
AS-602801
CAS Number:
848344-36-5
Molecular Formula:
C25H23N5O2S
Molecular Weight:
457.5474
MDL Number:
MFCD08272350
SMILES:
N#CC(c1nc2c(s1)cccc2)c1ccnc(n1)OCc1ccc(cc1)CN1CCOCC1
Properties
Computed Properties
 
Complexity:
660  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
33  
Hydrogen Bond Acceptor Count:
8  
Rotatable Bond Count:
7  
Undefined Atom Stereocenter Count:
1  
XLogP3:
3.3  

Literature

Title: The novel JNK inhibitor AS602801 inhibits cancer stem cells in vitro and in vivo.

Journal: Oncotarget 20160510

Title: c-Jun NH2-terminal kinase inhibitor bentamapimod reduces induced endometriosis in baboons: an assessor-blind placebo-controlled randomized study.

Journal: Fertility and sterility 20160301

Title: Bentamapimod (JNK Inhibitor AS602801) Induces Regression of Endometriotic Lesions in Animal Models.

Journal: Reproductive sciences (Thousand Oaks, Calif.) 20160101

Title: Letter: The formation of a semiquinone form of deazaFAD bound to D-amino acid oxidase.

Journal: Journal of the American Chemical Society 19760204

Title: Messoussi A, et al. Recent progress in the design, study, and development of c-Jun N-terminal kinase inhibitors as anticanceragents. Chem Biol. 2014 Nov 20;21(11):1433-43.

Title: Okada M, et al. The novel JNK inhibitor AS602801 inhibits cancer stem cells in vitro and in vivo. Oncotarget. 2016 May 10;7(19):27021-32.

Title: Palmer SS, et al. Bentamapimod (JNK Inhibitor AS602801) Induces Regression of Endometriotic Lesions in Animal Models. Reprod Sci. 2016 Jan;23(1):11-23.

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SDS
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