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142128-57-2,MFCD25509433
Catalog No.:AA01E1YC

142128-57-2 | 1-(4-(4-(((2S,4R)-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)ethanone

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10mg
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50mg
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01E1YC
Chemical Name:
1-(4-(4-(((2S,4R)-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)ethanone
CAS Number:
142128-57-2
Molecular Formula:
C26H28Cl2N4O4
Molecular Weight:
531.4309
MDL Number:
MFCD25509433
SMILES:
CC(=O)N1CCN(CC1)C2=CC=C(C=C2)OCC3COC(O3)(CN4C=CN=C4)C5=C(C=C(C=C5)Cl)Cl
UN Number:
2811
Properties
Computed Properties
 
Complexity:
735  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
36  
Hydrogen Bond Acceptor Count:
6  
Rotatable Bond Count:
7  
XLogP3:
4.3  

Literature

Title: Testosterone metabolism of equine single CYPs of the 3A subfamily compared to the human CYP3A4.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20170601

Title: Metabolic-induced cytotoxicity of diosbulbin B in CYP3A4-expressing cells.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20170201

Title: Identification of vitamin D(3) target genes in human breast cancer tissue.

Journal: The Journal of steroid biochemistry and molecular biology 20161101

Title: In vitro evaluation of hepatotoxic drugs in human hepatocytes from multiple donors: Identification of P450 activity as a potential risk factor for drug-induced liver injuries.

Journal: Chemico-biological interactions 20160805

Title: Modulation of 17β-estradiol induced estrogenic responses in male goldfish (Carassius auratus) by benzo[a]pyrene and ketoconazole.

Journal: Environmental science and pollution research international 20160501

Title: Metabolic activation of furan moiety makes Diosbulbin B hepatotoxic.

Journal: Archives of toxicology 20160401

Title: Ketoconazole Stereoisomers Differentially Induce Cytochrome P450 1A1 Between Human Hepatoma HepG2 and Mouse Hepatoma Hepa1c1c7 Cells.

Journal: Journal of pharmaceutical sciences 20160301

Title: Establishment of a mouse model for amiodarone-induced liver injury and analyses of its hepatotoxic mechanism.

Journal: Journal of applied toxicology : JAT 20160101

Title: Changes in plasma concentrations of corticosterone and its precursors after ketoconazole administration in rats: An application of simultaneous measurement of multiple steroids using LC-MS/MS.

Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20160101

Title: Cytotoxicity of luteolin in primary rat hepatocytes: the role of CYP3A-mediated ortho-benzoquinone metabolite formation and glutathione depletion.

Journal: Journal of applied toxicology : JAT 20151101

Title: Ketoconazole induces apoptosis in rat cardiomyocytes through reactive oxygen species-mediated parkin overexpression.

Journal: Archives of toxicology 20151001

Title: Testotoxicosis: Report of Two Cases, One with a Novel Mutation in LHCGR Gene.

Journal: Journal of clinical research in pediatric endocrinology 20150901

Title: Ketoconazole Treatment Decreases the Viability of Immortalized Pituitary Cell Lines Associated with an Increased Expression of Apoptosis-Related Genes and Cell Cycle Inhibitors.

Journal: Journal of neuroendocrinology 20150701

Title: Therapy of endocrine disease: steroidogenesis enzyme inhibitors in Cushing's syndrome.

Journal: European journal of endocrinology 20150601

Title: Demethylation of neferine in human liver microsomes and formation of quinone methide metabolites mediated by CYP3A4 accentuates its cytotoxicity.

Journal: Chemico-biological interactions 20141205

Title: Baboon syndrome induced by ketoconazole.

Journal: Cutaneous and ocular toxicology 20141201

Title: Clinical CYP3A inhibitor alternatives to ketoconazole, clarithromycin and itraconazole, are not transported into the liver by hepatic organic anion transporting polypeptides and organic cation transporter 1.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20141101

Title: Effects of rifampin and ketoconazole on pharmacokinetics of morinidazole in healthy chinese subjects.

Journal: Antimicrobial agents and chemotherapy 20141001

Title: Inhibition of cytochrome P450s enhances (+)-usnic acid cytotoxicity in primary cultured rat hepatocytes.

Journal: Journal of applied toxicology : JAT 20140801

Title: CYP3A4 activity reduces the cytotoxic effects of okadaic acid in HepaRG cells.

Journal: Archives of toxicology 20140801

Title: Studies on the antileishmanial mechanism of action of the arylimidamide DB766: azole interactions and role of CYP5122A1.

Journal: Antimicrobial agents and chemotherapy 20140801

Title: Investigation of a novel series of 2-hydroxyisoquinoline-1,3(2H,4H)-diones as human immunodeficiency virus type 1 integrase inhibitors.

Journal: Journal of medicinal chemistry 20140612

Title: Combination antiretroviral therapy (cART) component ritonavir significantly alters docetaxel exposure.

Journal: Cancer chemotherapy and pharmacology 20140401

Title: In vivo production of novel vitamin D2 hydroxy-derivatives by human placentas, epidermal keratinocytes, Caco-2 colon cells and the adrenal gland.

Journal: Molecular and cellular endocrinology 20140305

Title: Synthesis and biological evaluation of thiazoline derivatives as new antimicrobial and anticancer agents.

Journal: European journal of medicinal chemistry 20140303

Title: Synthesis, antifungal activities and molecular docking studies of novel 2-(2,4-difluorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl dithiocarbamates.

Journal: European journal of medicinal chemistry 20140303

Title: Molecular identification and antifungal susceptibility of yeast isolates causing fungemia collected in a population-based study in Spain in 2010 and 2011.

Journal: Antimicrobial agents and chemotherapy 20140301

Title: Targeted androgen pathway suppression in localized prostate cancer: a pilot study.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20140120

Title: Human variation and CYP enzyme contribution in benfuracarb metabolism in human in vitro hepatic models.

Journal: Toxicology letters 20140113

Title: Synthesis and biological evaluation of novel N-substituted 1H-dibenzo[a,c]carbazole derivatives of dehydroabietic acid as potential antimicrobial agents.

Journal: Bioorganic & medicinal chemistry letters 20140101

Title: Vitamin D up-regulates the vitamin D receptor by protecting it from proteasomal degradation in human CD4+ T cells.

Journal: PloS one 20140101

Title: Enantiospecific effects of ketoconazole on aryl hydrocarbon receptor.

Journal: PloS one 20140101

Title: Dual effects of ketoconazole cis-enantiomers on CYP3A4 in human hepatocytes and HepG2 Cells.

Journal: PloS one 20140101

Title: Capsaicin pretreatment increased the bioavailability of cyclosporin in rats: involvement of P-glycoprotein and CYP 3A inhibition.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20131201

Title: Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain.

Journal: Journal of natural products 20131122

Title: 3-Aryl-4-acyloxyethoxyfuran-2(5H)-ones as inhibitors of tyrosyl-tRNA synthetase: synthesis, molecular docking and antibacterial evaluation.

Journal: Bioorganic & medicinal chemistry 20130901

Title: Synthesis, in vitro antifungal activity and in silico study of 3-(1,2,4-triazol-1-yl)flavanones.

Journal: European journal of medicinal chemistry 20130801

Title: Interaction of 17β-estradiol and ketoconazole on endocrine function in goldfish (Carassius auratus).

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20130515

Title: Novel yeast-based strategy unveils antagonist binding regions on the nuclear xenobiotic receptor PXR.

Journal: The Journal of biological chemistry 20130510

Title: Effect of ketoconazole on the pharmacokinetics of the 11β-hydroxysteroid dehydrogenase type 1 inhibitor ABT-384 and its two active metabolites in healthy volunteers: population analysis of data from a drug-drug interaction study.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20130501

Title: Synthesis and evaluation of non-dimeric HCV NS5A inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20130401

Title: Coordinated roles of pregnane X receptor and constitutive androstane receptor in autoinduction of voriconazole metabolism in mice.

Journal: Antimicrobial agents and chemotherapy 20130301

Title: Transport inhibition of digoxin using several common P-gp expressing cell lines is not necessarily reporting only on inhibitor binding to P-gp.

Journal: PloS one 20130101

Title: Fluconazole inhibits human adrenocortical steroidogenesis in vitro.

Journal: The Journal of endocrinology 20121201

Title: Inhibition of CYP3A4 by 6',7'-dihydroxybergamottin in human CYP3A4 over-expressed hepG2 cells.

Journal: The Journal of pharmacy and pharmacology 20121201

Title: Binding processes determine the stereoselective intestinal and hepatic extraction of verapamil in vivo.

Journal: Molecular pharmaceutics 20121105

Title: A reappraisal of the medical therapy with steroidogenesis inhibitors in Cushing's syndrome.

Journal: Clinical endocrinology 20121101

Title: Catecholaminergic signalling through thymic nerve fibres, thymocytes and stromal cells is dependent on both circulating and locally synthesized glucocorticoids.

Journal: Experimental physiology 20121101

Title: Impact of nonlinear midazolam pharmacokinetics on the magnitude of the midazolam-ketoconazole interaction in rats.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20121101

Title: Assessment of the drug interaction risk for remogliflozin etabonate, a sodium-dependent glucose cotransporter-2 inhibitor: evidence from in vitro, human mass balance, and ketoconazole interaction studies.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20121101

Title: Synthesis and antifungal activity of diverse C-2 pyridinyl and pyridinylvinyl substituted quinolines.

Journal: Bioorganic & medicinal chemistry 20121101

Title: Synthesis, characterization and biological evaluation of some novel 2,4-thiazolidinediones as potential cytotoxic, antimicrobial and antihyperglycemic agents.

Journal: Bioorganic & medicinal chemistry letters 20121015

Title: Structure-activity relationship study of nitrosopyrimidines acting as antifungal agents.

Journal: Bioorganic & medicinal chemistry 20121015

Title: Evaluation of the effects of rifampicin, ketoconazole and erythromycin on the steady-state pharmacokinetics of the components of a novel oral contraceptive containing estradiol valerate and dienogest in healthy postmenopausal women.

Journal: Contraception 20121001

Title: Human aldosterone synthase: recombinant expression in E. coli and purification enables a detailed biochemical analysis of the protein on the molecular level.

Journal: The Journal of steroid biochemistry and molecular biology 20121001

Title: Course of pregnancies in women with Cushing's disease treated by gamma-knife.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20121001

Title: The effects on metabolic clearance when administering a potent CYP3A autoinducer with the prototypic CYP3A inhibitor, ketoconazole.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20121001

Title: Prototheca wickerhamii as a cause of neuroinfection in a child with congenital hydrocephalus. First case of human protothecosis in Poland.

Journal: Diagnostic microbiology and infectious disease 20121001

Title: Mouse precision-cut liver slices as an ex vivo model to study idiosyncratic drug-induced liver injury.

Journal: Chemical research in toxicology 20120917

Title: Identification of priority pharmaceuticals in the water environment of China.

Journal: Chemosphere 20120901

Title: Discovery of a highly selective CYP3A4 inhibitor suitable for reaction phenotyping studies and differentiation of CYP3A4 and CYP3A5.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20120901

Title: Studies on the mechanisms of superagonistic pro-differentiating activities of side-chain modified analogs of vitamin D2.

Journal: Oncology reports 20120901

Title: Involvement of the neurosteroid 7α-hydroxypregnenolone in the courtship behavior of the male newt Cynops pyrrhogaster.

Journal: Hormones and behavior 20120901

Title: Laurene-type sesquiterpenes from the Red Sea red alga Laurencia obtusa as potential antitumor-antimicrobial agents.

Journal: European journal of medicinal chemistry 20120901

Title: Effect of ketoconazole on the pharmacokinetic profile of buprenorphine following administration of a once-weekly buprenorphine transdermal system.

Journal: Clinical drug investigation 20120901

Title: Phase I studies of sirolimus alone or in combination with pharmacokinetic modulators in advanced cancer patients.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20120901

Title: Ascending single-dose study of the safety profile, tolerability, and pharmacokinetics of bosutinib coadministered with ketoconazole to healthy adult subjects.

Journal: Clinical therapeutics 20120901

Title: The prognostic factors of effective ketoconazole treatment for metastatic castration-resistant prostate cancer: who can benefit from ketoconazole therapy?

Journal: Asian journal of andrology 20120901

Title: Isolated Cushing's syndrome in early infancy due to left adrenal adenoma: an unusual aetiology.

Journal: Journal of clinical research in pediatric endocrinology 20120901

Title: Differentiating mucosal and hepatic metabolism of budesonide by local pretreatment with increasing doses of ketoconazole in the proximal jejunum.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120815

Title: Evaluation of saliva flow rates, Candida colonization and susceptibility of Candida strains after head and neck radiation.

Journal: Clinical oral investigations 20120801

Title: A randomized, crossover, placebo- and moxifloxacin-controlled study to evaluate the effects of bosutinib (SKI-606), a dual Src/Abl tyrosine kinase inhibitor, on cardiac repolarization in healthy adult subjects.

Journal: International journal of cancer 20120801

Title: In vitro activities of antifungal agents against clinical isolates of dermatophytes from animals.

Journal: The Journal of veterinary medical science 20120801

Title: Drug-drug interactions and cooperative effects detected in electrochemically driven human cytochrome P450 3A4.

Journal: Bioelectrochemistry (Amsterdam, Netherlands) 20120801

Title: Synthesis, antimicrobial and cytotoxic activities of sulfone linked bis heterocycles.

Journal: European journal of medicinal chemistry 20120801

Title: Synthesis and evaluation of novel potent HCV NS5A inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20120715

Title: Influence of Pluronic 85 and ketoconazole on disposition and efficacy of ivermectin in sheep infected with a multiple resistant Haemonchus contortus isolate.

Journal: Veterinary parasitology 20120706

Title: Synthesis of benzimidazolyl-1,3,4-oxadiazol-2ylthio-N-phenyl (benzothiazolyl) acetamides as antibacterial, antifungal and antituberculosis agents.

Journal: European journal of medicinal chemistry 20120701

Title: The fatty acid 8,11-diol synthase of Aspergillus fumigatus is inhibited by imidazole derivatives and unrelated to PpoB.

Journal: Lipids 20120701

Title: Bioactive briarane diterpenoids from the South China Sea gorgonian Dichotella gemmacea.

Journal: Bioorganic & medicinal chemistry letters 20120701

Title: CDR4 is the major contributor to azole resistance among four Pdr5p-like ABC transporters in Neurospora crassa.

Journal: Fungal biology 20120701

Title: Identification, synthesis, and biological evaluation of the metabolites of 3-amino-6-(3'-aminopropyl)-5H-indeno[1,2-c]isoquinoline-5,11-(6H)dione (AM6-36), a promising rexinoid lead compound for the development of cancer chemotherapeutic and chemopreventive agents.

Journal: Journal of medicinal chemistry 20120628

Title: Cytochrome P450 3A4 inhibition by ketoconazole: tackling the problem of ligand cooperativity using molecular dynamics simulations and free-energy calculations.

Journal: Journal of chemical information and modeling 20120625

Title: A time-course analysis of effects of the steroidogenesis inhibitor ketoconazole on components of the hypothalamic-pituitary-gonadal axis of fathead minnows.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20120615

Title: CYP3A-mediated apoptosis of dauricine in cultured human bronchial epithelial cells and in lungs of CD-1 mice.

Journal: Toxicology and applied pharmacology 20120615

Title: The effect of CYP3A4 inhibition or induction on the pharmacokinetics and pharmacodynamics of orally administered ruxolitinib (INCB018424 phosphate) in healthy volunteers.

Journal: Journal of clinical pharmacology 20120601

Title: Lack of significant effect of bilastine administered at therapeutic and supratherapeutic doses and concomitantly with ketoconazole on ventricular repolarization: results of a thorough QT study (TQTS) with QT-concentration analysis.

Journal: Journal of clinical pharmacology 20120601

Title: Tolbutamide hydroxylation by hepatic microsomes from Atlantic salmon (Salmo salar L.).

Journal: Molecular biology reports 20120601

Title: Design and synthesis of new 4-pyrazolin-3-yl-1,2,3-triazoles and 1,2,3-triazol-4-yl-pyrazolin-1-ylthiazoles as potential antimicrobial agents.

Journal: European journal of medicinal chemistry 20120601

Title: Distribution, behavior and fate of azole antifungals during mechanical, biological, and chemical treatments in sewage treatment plants in China.

Journal: The Science of the total environment 20120601

Title: Apparent triclabendazole-resistant human Fasciola hepatica infection, the Netherlands.

Journal: Emerging infectious diseases 20120601

Title: Influence of P-glycoprotein modulation on plasma concentrations and pharmacokinetics of orally administered prednisolone in dogs.

Journal: American journal of veterinary research 20120601

Title: Fluconazole exposure rather than clonal spreading is correlated with the emergence of Candida glabrata with cross-resistance to triazole antifungal agents.

Journal: The Kaohsiung journal of medical sciences 20120601

Title: Implication of free cholesterol in LC-MS response enhancement.

Journal: Bioanalysis 20120601

Title: Therapeutic effectiveness of Ageratina pichinchensis on the treatment of chronic interdigital tinea pedis: a randomized, double-blind clinical trial.

Journal: Journal of alternative and complementary medicine (New York, N.Y.) 20120601

Title: Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.

Journal: Journal of medicinal chemistry 20120524

Title: Effects of ketoconazole and valproic acid on the pharmacokinetics of the next generation NNRTI, lersivirine (UK-453,061), in healthy adult subjects.

Journal: British journal of clinical pharmacology 20120501

Title: Drug-drug interactions between ketoconazole and berberine in rats: pharmacokinetic effects benefit pharmacodynamic synergism.

Journal: Phytotherapy research : PTR 20120501

Title: The effect of multiple doses of rifampin and ketoconazole on the single-dose pharmacokinetics of ridaforolimus.

Journal: Cancer chemotherapy and pharmacology 20120501

Title: Human testis steroidogenesis is inhibited by phthalates.

Journal: Human reproduction (Oxford, England) 20120501

Title: Synthesis of novel spirooxindole derivatives by one pot multicomponent reaction and their antimicrobial activity.

Journal: European journal of medicinal chemistry 20120501

Title: Preclinical metabolism of LB42908, a novel farnesyl transferase inhibitor, and its effects on the cytochrome P450 isozyme activities.

Journal: Bioorganic & medicinal chemistry letters 20120501

Title: The stepwise selection for ketoconazole resistance induces upregulation of C14-demethylase (CYP51) in Leishmania amazonensis.

Journal: Memorias do Instituto Oswaldo Cruz 20120501

Title: Stereoselective metabolism of tetrahydropalmatine enantiomers in rat liver microsomes.

Journal: Chirality 20120501

Title: Effects of ketoconazole and rifampicin on the pharmacokinetics of gemigliptin, a dipeptidyl peptidase-IV inhibitor: a crossover drug-drug interaction study in healthy male Korean volunteers.

Journal: Clinical therapeutics 20120501

Title: Hydrogel of ketoconazole and PAMAM dendrimers: formulation and antifungal activity.

Journal: Molecules (Basel, Switzerland) 20120418

Title: New triazole derivatives as antifungal agents: synthesis via click reaction, in vitro evaluation and molecular docking studies.

Journal: Bioorganic & medicinal chemistry letters 20120415

Title: Development of a new class of aromatase inhibitors: design, synthesis and inhibitory activity of 3-phenylchroman-4-one (isoflavanone) derivatives.

Journal: Bioorganic & medicinal chemistry 20120415

Title: Molecular cloning, characterization, and inhibition studies of a β-carbonic anhydrase from Malassezia globosa, a potential antidandruff target.

Journal: Journal of medicinal chemistry 20120412

Title: Effect of cytochrome P450 3A4 inhibitor ketoconazole on risperidone pharmacokinetics in healthy volunteers.

Journal: Journal of clinical pharmacy and therapeutics 20120401

Title: Involvement of P-glycoprotein and cytochrome P450 3A in the metabolism of florfenicol of rabbits.

Journal: Journal of veterinary pharmacology and therapeutics 20120401

Title: Effects of CYP3A4 inhibition and induction on the pharmacokinetics and pharmacodynamics of tolvaptan, a non-peptide AVP antagonist in healthy subjects.

Journal: British journal of clinical pharmacology 20120401

Title: Iatrogenic heart block during treatment of a patient with Cushing's syndrome: report of a case.

Journal: Endocrine 20120401

Title: Orteronel (TAK-700), a novel non-steroidal 17,20-lyase inhibitor: effects on steroid synthesis in human and monkey adrenal cells and serum steroid levels in cynomolgus monkeys.

Journal: The Journal of steroid biochemistry and molecular biology 20120401

Title: The hypercoagulable state in Cushing's disease is associated with increased levels of procoagulant factors and impaired fibrinolysis, but is not reversible after short-term biochemical remission induced by medical therapy.

Journal: The Journal of clinical endocrinology and metabolism 20120401

Title: Predicting drug candidate victims of drug-drug interactions, using microdosing.

Journal: Clinical pharmacokinetics 20120401

Title: Increasing evidence for and regulation of a human placental endogenous digitalis-like factor.

Journal: Reproductive sciences (Thousand Oaks, Calif.) 20120401

Title: Regioselective synthesis and antimicrobial activities of some novel aryloxyacetic acid derivatives.

Journal: European journal of medicinal chemistry 20120401

Title: Comparison of three fluorescent CYP3A substrates in two vertebrate models: pig and Atlantic salmon.

Journal: Animal : an international journal of animal bioscience 20120401

Title: In vitro antifungal susceptibility of Malassezia pachydermatis from dogs with and without skin lesions.

Journal: Veterinary microbiology 20120323

Title: Contemporary experience with ketoconazole in patients with metastatic castration-resistant prostate cancer: clinical factors associated with PSA response and disease progression.

Journal: The Prostate 20120301

Title: Pharmacokinetic interaction between domperidone and ketoconazole leads to QT prolongation in healthy volunteers: a randomized, placebo-controlled, double-blind, crossover study.

Journal: British journal of clinical pharmacology 20120301

Title: H295R cells as a model for steroidogenic disruption: a broader perspective using simultaneous chemical analysis of 7 key steroid hormones.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20120301

Title: Hypercalcemia, hypercalciuria, and elevated calcitriol concentrations with autosomal dominant transmission due to CYP24A1 mutations: effects of ketoconazole therapy.

Journal: The Journal of clinical endocrinology and metabolism 20120301

Title: Take another CYP: confirming a novel mechanism for 'idiopathic' hypercalcemia.

Journal: The Journal of clinical endocrinology and metabolism 20120301

Title: An Aruban man with fever, abdominal mass and eosinophilia.

Journal: The Netherlands journal of medicine 20120301

Title: Potentiation of triclabendazole action in vivo against a triclabendazole-resistant isolate of Fasciola hepatica following its co-administration with the metabolic inhibitor, ketoconazole.

Journal: Veterinary parasitology 20120227

Title: Tocol modified glycol chitosan for the oral delivery of poorly soluble drugs.

Journal: International journal of pharmaceutics 20120227

Title: [Efficacy of low dose ketoconazole therapy for Chinese patients with castration resistant prostate cancer].

Journal: Zhonghua yi xue za zhi 20120227

Title: Synthesis of novel brassinosteroid biosynthesis inhibitors based on the ketoconazole scaffold.

Journal: Bioorganic & medicinal chemistry letters 20120215

Title: Synthesis of novel sulfonamide-1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and conformational analysis studies.

Journal: Bioorganic & medicinal chemistry 20120215

Title: Effect of ketoconazole on the pharmacokinetics of axitinib in healthy volunteers.

Journal: Investigational new drugs 20120201

Title: Malformation spectrum induced by ketoconazole after single administration to pregnant rats during the critical period - comparison with vitamin A-induced malformation spectrum.

Journal: Journal of applied toxicology : JAT 20120201

Title: Enhancement of β-carotene production by over-expression of HMG-CoA reductase coupled with addition of ergosterol biosynthesis inhibitors in recombinant Saccharomyces cerevisiae.

Journal: Current microbiology 20120201

Title: Synthesis and biological evaluation of some thiazolidinones as antimicrobial agents.

Journal: European journal of medicinal chemistry 20120201

Title: Ketoconazole-associated preferential increase in dopamine D2 receptor occupancy in striatum compared to pituitary in vivo: role for drug transporters?

Journal: Journal of clinical psychopharmacology 20120201

Title: Effects of efonidipine on the pharmacokinetics and pharmacodynamics of repaglinide: possible role of CYP3A4 and P-glycoprotein inhibition by efonidipine.

Journal: Journal of pharmacokinetics and pharmacodynamics 20120201

Title: [Blastomycosis in Morocco: imported mycosis].

Journal: Revue de pneumologie clinique 20120201

Title: Advances in medical therapies for Cushing's syndrome.

Journal: Discovery medicine 20120201

Title: [Transport of limonin in rat intestine in situ and Caco-2 cells in vitro].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20120201

Title: Tinea versicolor: understanding effective treatment options.

Journal: The Nurse practitioner 20120119

Title: Synthesis, characterization and in vitro biological evaluation of some novel diarylsulfonylureas as potential cytotoxic and antimicrobial agents.

Journal: Bioorganic & medicinal chemistry letters 20120115

Title: Radiation port dermatophytosis: tinea corporis occurring at the site of irradiated skin.

Journal: Dermatology online journal 20120115

Title: Determination of metabolic profile of anti-malarial trioxane CDRI 99/411 in rat liver microsomes using HPLC.

Journal: Biomedical chromatography : BMC 20120101

Title: Identification of ketoconazole as an AhR-Nrf2 activator in cultured human keratinocytes: the basis of its anti-inflammatory effect.

Journal: The Journal of investigative dermatology 20120101

Title: Application of PBPK modelling in drug discovery and development at Pfizer.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20120101

Title: Ultrasound-enhanced surfactant-assisted dispersive liquid-liquid microextraction and high-performance liquid chromatography for determination of ketoconazole and econazole nitrate in human blood.

Journal: Analytical and bioanalytical chemistry 20120101

Title: Discovery of a novel class of aldol-derived 1,2,3-triazoles: potent and selective inhibitors of human cytochrome P450 19A1 (aromatase).

Journal: Bioorganic & medicinal chemistry letters 20120101

Title: Antifungal activities of novel non-azole molecules against S. cerevisiae and C. albicans.

Journal: European journal of medicinal chemistry 20120101

Title: Synthesis, antimicrobial, antimycobacterial and structure-activity relationship of substituted pyrazolo-, isoxazolo-, pyrimido- and mercaptopyrimidocyclohepta[b]indoles.

Journal: European journal of medicinal chemistry 20120101

Title: Isoxazoles incorporated N-substituted decahydroquinolines: a precursor to the next generation antimicrobial drug.

Journal: European journal of medicinal chemistry 20120101

Title: The AhR-Nrf2 pathway in keratinocytes: on the road to chemoprevention?

Journal: The Journal of investigative dermatology 20120101

Title: Lack of drug interaction between the migraine drug MAP0004 (orally inhaled dihydroergotamine) and a CYP3A4 inhibitor in humans.

Journal: Cephalalgia : an international journal of headache 20120101

Title: Comparison of the effect of non-antifungal and antifungal agents on Candida isolates from the gastrointestinal tract.

Journal: Archives of Iranian medicine 20120101

Title: Efficacy and safety of venous thromboembolism prophylaxis with apixaban in major orthopedic surgery.

Journal: Therapeutics and clinical risk management 20120101

Title: Roles of adapalene in the treatment of pityriasis versicolor.

Journal: Dermatology (Basel, Switzerland) 20120101

Title: The effect of ketoconazole on post-burn inflammation, hypermetabolism and clinical outcomes.

Journal: PloS one 20120101

Title: Disappearance of pituitary macro adenoma with combination of ketoconazole and cabergoline treatment: an unusual case of Cushing's syndrome with interesting findings.

Journal: BMJ case reports 20120101

Title: Stimulation of human monocytic THP-1 cells by metabolic activation of hepatotoxic drugs.

Journal: Drug metabolism and pharmacokinetics 20120101

Title: Retigeric acid B enhances the efficacy of azoles combating the virulence and biofilm formation of Candida albicans.

Journal: Biological & pharmaceutical bulletin 20120101

Title: Comparison between two culture media for in vitro evaluation of antifungal susceptibility of the Sporothrix schenckii complex.

Journal: Anais brasileiros de dermatologia 20120101

Title: Telaprevir: pharmacokinetics and drug interactions.

Journal: Antiviral therapy 20120101

Title: Blockade of K+ and Ca2+ channels by azole antifungal agents in neonatal rat ventricular myocytes.

Journal: Biological & pharmaceutical bulletin 20120101

Title: The cytochrome P450 inhibitor, ketoconazole, inhibits oxidized linoleic acid metabolite-mediated peripheral inflammatory pain.

Journal: Molecular pain 20120101

Title: Synthesis and antileishmanial evaluation of 1-aryl-4-(4,5-dihydro-1H-imidazol-2-yl)-1H-pyrazole derivatives.

Journal: Bioorganic & medicinal chemistry letters 20111215

Title: A new antifungal briarane diterpenoid from the gorgonian Junceella juncea Pallas.

Journal: Bioorganic & medicinal chemistry letters 20111215

Title: Novel (E)-1-(4-methyl-2-(alkylamino)thiazol-5-yl)-3-arylprop-2-en-1-ones as potent antimicrobial agents.

Journal: Bioorganic & medicinal chemistry 20111215

Title: Effect of ketoconazole on the pharmacokinetics of oral bosutinib in healthy subjects.

Journal: Journal of clinical pharmacology 20111201

Title: Precipitation in and supersaturation of contents of the upper small intestine after administration of two weak bases to fasted adults.

Journal: Pharmaceutical research 20111201

Title: Cytotoxicity of 3-(3,5-dichlorophenyl)-2,4-thiazolidinedione (DCPT) and analogues in wild type and CYP3A4 stably transfected HepG2 cells.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20111201

Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Journal: PLoS computational biology 20111201

Title: Effect of different durations and formulations of diltiazem on the single-dose pharmacokinetics of midazolam: how long do we go?

Journal: Journal of clinical pharmacology 20111101

Title: Effect of hyperlipidemia on ketoconazole-midazolam drug-drug interaction in rat.

Journal: Journal of pharmaceutical sciences 20111101

Title: A random comparative study of terbinafine versus griseofulvin in patients with tinea capitis in Western China.

Journal: Mycopathologia 20111101

Title: Antifungal susceptibility and virulence attributes of bloodstream isolates of Candida from Hong Kong and Finland.

Journal: Mycopathologia 20111101

Title: Synthesis and antimicrobial activity of amido linked pyrrolyl and pyrazolyl-oxazoles, thiazoles and imidazoles.

Journal: European journal of medicinal chemistry 20111101

Title: Synthesis and biological evaluation of some novel triazol-3-ones as antimicrobial agents.

Journal: Bioorganic & medicinal chemistry letters 20111101

Title: Synthesis and anticandidal activity of new triazolothiadiazine derivatives.

Journal: European journal of medicinal chemistry 20111101

Title: The influence of modulation of P-glycoprotein and /or cytochrome P450 3A on the pharmacokinetics and pharmacodynamics of orally administered morphine in dogs.

Journal: Journal of veterinary pharmacology and therapeutics 20111001

Title: Exploring the possible metabolism mediated interaction of Glycyrrhiza glabra extract with CYP3A4 and CYP2D6.

Journal: Phytotherapy research : PTR 20111001

Title: Inhibition of triclabendazole metabolism in vitro by ketoconazole increases disruption to the tegument of a triclabendazole-resistant isolate of Fasciola hepatica.

Journal: Parasitology research 20111001

Title: Overt immune dysfunction after Cushing's syndrome remission: a consecutive case series and review of the literature.

Journal: The Journal of clinical endocrinology and metabolism 20111001

Title: Tyrosyl-tRNA synthetase inhibitors as antibacterial agents: synthesis, molecular docking and structure-activity relationship analysis of 3-aryl-4-arylaminofuran-2(5H)-ones.

Journal: European journal of medicinal chemistry 20111001

Title: Enantioselective capillary electrophoresis for the assessment of CYP3A4-mediated ketamine demethylation and inhibition in vitro.

Journal: Electrophoresis 20111001

Title: Effects of CYP inhibitors on precocene I metabolism and toxicity in rat liver slices.

Journal: Chemico-biological interactions 20110905

Title: Therapeutic efficacy of topical OLEOZON® in patients suffering from onychomycosis.

Journal: Mycoses 20110901

Title: Successful outcome of pregnancy in a patient with Cushing's disease under treatment with ketoconazole during the first trimester of gestation.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20110901

Title: Investigating the effect of moisture protection on solid-state stability and dissolution of fenofibrate and ketoconazole solid dispersions using PXRD, HSDSC and Raman microscopy.

Journal: Drug development and industrial pharmacy 20110901

Title: Arachidonic acid products in airway nociceptor activation during acute lung injury.

Journal: Experimental physiology 20110901

Title: Molecular complexes of ketaconazole and oxatomide with p-chloranil: spectroscopic and spectrofluorimetric studies.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20110901

Title: Design, synthesis and antimicrobial activity of chiral 2-(substituted-hydroxyl)-3-(benzo[d]oxazol-5-yl)propanoic acid derivatives.

Journal: European journal of medicinal chemistry 20110901

Title: A novel biotransformation of alkyl aminopyrrolidine to aminopiperidine ring by human CYP3A.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20110901

Title: Effect of ketoconazole-mediated CYP3A4 inhibition on clinical pharmacokinetics of panobinostat (LBH589), an orally active histone deacetylase inhibitor.

Journal: Cancer chemotherapy and pharmacology 20110901

Title: Mitotane, metyrapone, and ketoconazole combination therapy as an alternative to rescue adrenalectomy for severe ACTH-dependent Cushing's syndrome.

Journal: The Journal of clinical endocrinology and metabolism 20110901

Title: A phase II clinical trial of neoadjuvant ketoconazole and docetaxel chemotherapy before radical prostatectomy in high risk patients.

Journal: The Journal of urology 20110901

Title: Editorial comment.

Journal: The Journal of urology 20110901

Title: Synthesis and studies of novel 2-(4-cyano-3-trifluoromethylphenyl amino)-4-(quinoline-4-yloxy)-6-(piperazinyl/piperidinyl)-s-triazines as potential antimicrobial, antimycobacterial and anticancer agents.

Journal: European journal of medicinal chemistry 20110901

Title: Pulmonary histoplasmosis presenting with the reversed halo sign on high-resolution CT scan.

Journal: Chest 20110901

Title: In vitro susceptibility of fluconazole-susceptible and -resistant isolates of Malassezia pachydermatis against azoles.

Journal: Veterinary microbiology 20110826

Title: Cytotoxic bipyridines from the marine-derived actinomycete Actinoalloteichus cyanogriseus WH1-2216-6.

Journal: Journal of natural products 20110826

Title: Hydroxylation of DHEA, androstenediol and epiandrosterone by Mortierella isabellina AM212. Evidence indicating that both constitutive and inducible hydroxylases catalyze 7α- as well as 7β-hydroxylations of 5-ene substrates.

Journal: Organic & biomolecular chemistry 20110807

Title: The effect of vitamin D3 and ketoconazole combination on VDR-mediated P-gp expression and function in human colon adenocarcinoma cells: implications in drug disposition and resistance.

Journal: Basic & clinical pharmacology & toxicology 20110801

Title: Effects of strong CYP2D6 and 3A4 inhibitors, paroxetine and ketoconazole, on the pharmacokinetics and cardiovascular safety of tamsulosin.

Journal: British journal of clinical pharmacology 20110801

Title: Substrate specificity and ligand interactions of CYP26A1, the human liver retinoic acid hydroxylase.

Journal: Molecular pharmacology 20110801

Title: Hepatic cytochrome P450s attenuate the cytotoxicity induced by leflunomide and its active metabolite A77 1726 in primary cultured rat hepatocytes.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20110801

Title: Synthesis and antimicrobial evaluation of new benzofuran derivatives.

Journal: European journal of medicinal chemistry 20110801

Title: The pharmacological inhibition of sterol biosynthesis in Leishmania is counteracted by enhancement of LDL endocytosis.

Journal: Acta tropica 20110801

Title: Improved treatment of visceral leishmaniasis (kala-azar) by using combination of ketoconazole, miltefosine with an immunomodulator-Picroliv.

Journal: Acta tropica 20110801

Title: Higher throughput human hepatocyte assays for the evaluation of time-dependent inhibition of CYP3A4.

Journal: Drug metabolism letters 20110801

Title: Auto-inhibition of verapamil metabolism in rat hepatocytes of gel entrapment culture.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20110801

Title: Bioactive 11,20-epoxy-3,5(16)-diene briarane diterpenoids from the South China Sea gorgonian Dichotella gemmacea.

Journal: Journal of natural products 20110722

Title: Spanlastics--a novel nanovesicular carrier system for ocular delivery.

Journal: International journal of pharmaceutics 20110715

Title: Bioavailability considerations in evaluating drug-drug interactions using the population pharmacokinetic approach.

Journal: Journal of clinical pharmacology 20110701

Title: Low dose of ketoconazole in patients with prostate adenocarcinoma resistant to pharmacological castration.

Journal: BJU international 20110701

Title: Nanoparticle formation and growth during in vitro dissolution of ketoconazole solid dispersion.

Journal: Journal of pharmaceutical sciences 20110701

Title: Fenretinide metabolism in humans and mice: utilizing pharmacological modulation of its metabolic pathway to increase systemic exposure.

Journal: British journal of pharmacology 20110701

Title: Secondary hormonal manipulations in the treatment of castration refractory prostate cancer.

Journal: BJU international 20110701

Title: Design, synthesis and antifungal activities of novel 1,2,4-triazole derivatives.

Journal: European journal of medicinal chemistry 20110701

Title: Antifungal quinazolinones from marine-derived Bacillus cereus and their preparation.

Journal: Bioorganic & medicinal chemistry letters 20110701

Title: Practical synthesis, anticonvulsant, and antimicrobial activity of N-allyl and N-propargyl di(indolyl)indolin-2-ones.

Journal: Bioorganic & medicinal chemistry letters 20110701

Title: 4-alkoxy-3-arylfuran-2(5H)-ones as inhibitors of tyrosyl-tRNA synthetase: synthesis, molecular docking and antibacterial evaluation.

Journal: Bioorganic & medicinal chemistry 20110701

Title: Efficacious and safe management of moderate to severe scalp seborrhoeic dermatitis using clobetasol propionate shampoo 0·05% combined with ketoconazole shampoo 2%: a randomized, controlled study.

Journal: The British journal of dermatology 20110701

Title: Synergistic effects of tetrandrine on the antifungal activity of topical ketoconazole cream in the treatment of dermatophytoses: a clinical trial.

Journal: Chinese journal of integrative medicine 20110701

Title: Drug metabolism of CYP3A4, CYP2C9 and CYP2D6 substrates in pigs and humans.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20110614

Title: Investigating effect of microemulsion components: In vitro permeation of ketoconazole.

Journal: Pharmaceutical development and technology 20110601

Title: Prevalence and antifungal resistance profile of Candida spp. oral isolates from patients with type 1 and 2 diabetes mellitus.

Journal: Archives of oral biology 20110601

Title: Cushing's syndrome due to a pancreatic neuroendocrine tumor metastatic to the ovaries: a clinicopathological description of a case.

Journal: Endocrine pathology 20110601

Title: Melatonin and steroid hormones activate intermembrane Cu,Zn-superoxide dismutase by means of mitochondrial cytochrome P450.

Journal: Free radical biology & medicine 20110601

Title: Tinea capitis versus acne keloidalis nuchae with Trichophyton violaceum superinfection.

Journal: Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia 20110601

Title: [Bilateral conjunctival oedema as a symptom of adrenal adenocarcinoma].

Journal: Archivos de la Sociedad Espanola de Oftalmologia 20110601

Title: Pseudotumor cerebri during Cushing's disease treatment with ketoconazole.

Journal: Arquivos brasileiros de endocrinologia e metabologia 20110601

Title: Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation.

Journal: Bioorganic & medicinal chemistry 20110515

Title: Enhancement of triclabendazole action in vivo against a triclabendazole-resistant isolate of Fasciola hepatica by co-treatment with ketoconazole.

Journal: Veterinary parasitology 20110511

Title: In vivo investigation in pigs of intestinal absorption, hepatobiliary disposition, and metabolism of the 5α-reductase inhibitor finasteride and the effects of coadministered ketoconazole.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20110501

Title: Synthesis, antimicrobial, antioxidant, anti-hemolytic and cytotoxic evaluation of new imidazole-based heterocycles.

Journal: European journal of medicinal chemistry 20110501

Title: Assessment of milling-induced disorder of two pharmaceutical compounds.

Journal: Journal of pharmaceutical sciences 20110501

Title: Management of pituitary tumors in pregnancy.

Journal: Nature reviews. Endocrinology 20110501

Title: Antifungal, cytotoxic and SAR studies of a series of N-alkyl, N-aryl and N-alkylphenyl-1,4-pyrrolediones and related compounds.

Journal: Bioorganic & medicinal chemistry 20110501

Title: The effects of concurrent administration of cytochrome P-450 inhibitors on the pharmacokinetics of oral methadone in healthy dogs.

Journal: Veterinary anaesthesia and analgesia 20110501

Title: [Management of invasive fungal infections in children].

Journal: Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20110501

Title: An azole-resistant isolate of Malassezia pachydermatis.

Journal: Veterinary microbiology 20110421

Title: Fine-tuning the selectivity of aldosterone synthase inhibitors: structure-activity and structure-selectivity insights from studies of heteroaryl substituted 1,2,5,6-tetrahydropyrrolo[3,2,1-ij]quinolin-4-one derivatives.

Journal: Journal of medicinal chemistry 20110414

Title: Synthesis and biological activity of 2-(bis((1,3,4-oxadiazolyl/1,3,4-thiadiazolyl)methylthio)methylene)malononitriles.

Journal: European journal of medicinal chemistry 20110401

Title: Concurrent assessment of hepatic and intestinal cytochrome P450 3A activities using deuterated alfentanil.

Journal: Clinical pharmacology and therapeutics 20110401

Title: Pharmacokinetics of oral neratinib during co-administration of ketoconazole in healthy subjects.

Journal: British journal of clinical pharmacology 20110401

Title: Pharmacokinetic interactions between alitretinoin and ketoconazole or simvastatin or ciclosporin A.

Journal: Clinical and experimental dermatology 20110401

Title: Inhibitory effects of ketoconazole and rifampin on OAT1 and OATP1B1 transport activities: considerations on drug-drug interactions.

Journal: Biopharmaceutics & drug disposition 20110401

Title: Nonhealing scalp wound infected with Aspergillus niger in an elderly patient.

Journal: Cutis 20110401

Title: Low dose of ketoconazole in patients with prostate adenocarcinoma resistant to pharmacological castration.

Journal: BJU international 20110401

Title: Design, synthesis, and biological evaluation of imidazolyl derivatives of 4,7-disubstituted coumarins as aromatase inhibitors selective over 17-α-hydroxylase/C17-20 lyase.

Journal: Journal of medicinal chemistry 20110324

Title: Marginal increase of sunitinib exposure by grapefruit juice.

Journal: Cancer chemotherapy and pharmacology 20110301

Title: Crucial role of cytochrome P450 in hepatotoxicity induced by 2,3-dimethoxy-1,4-naphthoquinone in rats.

Journal: Journal of applied toxicology : JAT 20110301

Title: Evaluation of the origin of a sample of Sporothrix schenckii that caused contamination of a researcher in Southern Brazil.

Journal: Mycopathologia 20110301

Title: CYP3A-mediated generation of aldehyde and hydrazine in atazanavir metabolism.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20110301

Title: Synthesis, structure, molecular docking, and structure-activity relationship analysis of enamines: 3-aryl-4-alkylaminofuran-2(5H)-ones as potential antibacterials.

Journal: Bioorganic & medicinal chemistry 20110301

Title: [Castration resistant prostate cancer 2011].

Journal: Aktuelle Urologie 20110301

Title: First description of onychomycosis caused by Chrysosporium keratinophilum in captive Bennett's wallabies (Macropus rufogriseus rufogriseus).

Journal: Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20110301

Title: Unexpected effect of rifampin on the pharmacokinetics of linezolid: in silico and in vitro approaches to explain its mechanism.

Journal: Journal of clinical pharmacology 20110201

Title: Effects of ketoconazole on the in vivo biotransformation and hepatobiliary transport of the thrombin inhibitor AZD0837 in pigs.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20110201

Title: The effect of increased lipoprotein levels on the pharmacokinetics of ketoconazole enantiomers in the rat.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20110201

Title: Application of validated RP-HPLC method for simultaneous determination of docetaxel and ketoconazole in solid lipid nanoparticles.

Journal: Journal of chromatographic science 20110201

Title: Mechanism of cytochrome P450-3A inhibition by ketoconazole.

Journal: The Journal of pharmacy and pharmacology 20110201

Title: [Evaluation of efficacy of ketoconazole 800 mg-clindamycin 100 mg tablets vaginal against ketoconazole 800 mg- clindamycin 100 mg vaginal capsules in candida vaginitis and vaginosis].

Journal: Ginecologia y obstetricia de Mexico 20110201

Title: Cytochrome P450 3A4 inhibitory constituents of the wood of Taxus yunnanensis.

Journal: Journal of natural products 20110128

Title: Radical scavenging and antioxidant activities of isocoumarins and a phthalide from the endophytic fungus Colletotrichum sp.

Journal: Journal of natural products 20110128

Title: New drug-like hydroxyphenylnaphthol steroidomimetics as potent and selective 17β-hydroxysteroid dehydrogenase type 1 inhibitors for the treatment of estrogen-dependent diseases.

Journal: Journal of medicinal chemistry 20110127

Title: A species-specific approach to the use of non-antimony treatments for cutaneous leishmaniasis.

Journal: The American journal of tropical medicine and hygiene 20110105

Title: A case of kerion celsi caused by Microsporum gypseum in a boy following dermatoplasty for a scalp wound from a road accident.

Journal: Medical mycology 20110101

Title: Effects of rifampin and ketoconazole on the pharmacokinetics of nilotinib in healthy participants.

Journal: Journal of clinical pharmacology 20110101

Title: Effect of the inhibition of CYP3A4 or CYP2D6 on the pharmacokinetics and pharmacodynamics of oxycodone.

Journal: European journal of clinical pharmacology 20110101

Title: Identification of human liver cytochrome P450 enzymes involved in the metabolism of SCH 530348 (Vorapaxar), a potent oral thrombin protease-activated receptor 1 antagonist.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20110101

Title: Ketoconazole and miconazole alter potassium homeostasis in Saccharomyces cerevisiae.

Journal: Biochimica et biophysica acta 20110101

Title: N-(Pyridin-3-yl)benzamides as selective inhibitors of human aldosterone synthase (CYP11B2).

Journal: Bioorganic & medicinal chemistry letters 20110101

Title: 3-[Benzimidazo- and 3-[benzothiadiazoleimidazo-(1,2-c)quinazolin-5-yl]-2H-chromene-2-ones as potent antimicrobial agents.

Journal: Bioorganic & medicinal chemistry letters 20110101

Title: CYP1A2-mediated biotransformation of cardioactive 2-thienylidene-3,4-methylenedioxybenzoylhydrazine (LASSBio-294) by rat liver microsomes and human recombinant CYP enzymes.

Journal: European journal of medicinal chemistry 20110101

Title: Fixed drug eruptions induced by cross-reactive imidazoles.

Journal: Allergologia et immunopathologia 20110101

Title: [Onychomycosis-causing yeasts in four Mexican dermatology centers and their antifungal susceptibility to azolic compounds].

Journal: Revista iberoamericana de micologia 20110101

Title: Evaluation of the pharmacokinetic interaction of midazolam with ursodeoxycholic acid, ketoconazole and dexamethasone by brain benzodiazepine receptor occupancy.

Journal: The Journal of pharmacy and pharmacology 20110101

Title: Inhibitory effects of Phyllanthus amarus and its major lignans on human microsomal cytochrome P450 activities: evidence for CYP3A4 mechanism-based inhibition.

Journal: Drug metabolism and pharmacokinetics 20110101

Title: In vitro antifungal susceptibility of Candida spp. oral isolates from HIV-positive patients and control individuals.

Journal: Brazilian oral research 20110101

Title: Patient preferences and treatment safety for uncomplicated vulvovaginal candidiasis in primary health care.

Journal: BMC public health 20110101

Title: Oropharyngeal histoplasmosis: report of eleven cases and review of the literature.

Journal: Revista da Sociedade Brasileira de Medicina Tropical 20110101

Title: [Determination of hemolytic activity and in vitro antifungal susceptibility of Trichophyton rubrum clinical strains].

Journal: Mikrobiyoloji bulteni 20110101

Title: Disturbance in hemoglobin metabolism and in vivo antimalarial activity of azole antimycotics.

Journal: Revista do Instituto de Medicina Tropical de Sao Paulo 20110101

Title: Physicochemical characterization and dissolution study of solid dispersions of ketoconazole with nicotinamide.

Journal: Chemical & pharmaceutical bulletin 20110101

Title: Overexpression of CYP3A4, but not of CYP2D6, promotes hypoxic response and cell growth of Hep3B cells.

Journal: Drug metabolism and pharmacokinetics 20110101

Title: Cushing syndrome due to ectopic adrenocorticotropic hormone secretion in a 3-year-old child.

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20110101

Title: [Scedosporium apiospermum disseminated infection in a single lung transplant recipient].

Journal: Revista iberoamericana de micologia 20110101

Title: Effectiveness of chronic treatment with ketoconazole in a patient with diabetic Cushing's disease resistant to surgery.

Journal: Endokrynologia Polska 20110101

Title: Oral cavity eumycetoma.

Journal: Revista do Instituto de Medicina Tropical de Sao Paulo 20110101

Title: [Immunorehabilitation in patients with paecilomycosis-complicated echinococcosis and asthma].

Journal: Meditsinskaia parazitologiia i parazitarnye bolezni 20110101

Title: Trypanosoma cruzi epimastigotes are able to store and mobilize high amounts of cholesterol in reservosome lipid inclusions.

Journal: PloS one 20110101

Title: Nocardia transvalensis keratitis: an emerging pathology among travelers returning from Asia.

Journal: BMC infectious diseases 20110101

Title: Prevalence of exocrine pancreatic insufficiency in women with obesity syndrome: assessment by pancreatic fecal elastase 1.

Journal: ISRN gastroenterology 20110101

Title: Pneumocystis pneumonia during medicamentous treatment of Cushing's syndrome--a description of two cases.

Journal: Acta medica (Hradec Kralove) 20110101

Title: New aspects in the clinical course of pityriasis versicolor.

Journal: Anais brasileiros de dermatologia 20110101

Title: Oral antifungal therapy for chronic rhinosinusitis and its subtypes: a systematic review.

Journal: International forum of allergy & rhinology 20110101

Title: Pilot Study of 15 Patients Receiving a New Treatment Regimen for Androgenic Alopecia: The Effects of Atopy on AGA.

Journal: ISRN dermatology 20110101

Title: Prophylactic ketoconazole shampoo for tinea capitis in a high-risk pediatric population.

Journal: The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG 20110101

Title: Optimization of a novel method based on solidification of floating organic droplet by high-performance liquid chromatography for evaluation of antifungal drugs in biological samples.

Journal: Talanta 20101215

Title: Structural interpretation in composite systems using powder X-ray diffraction: applications of error propagation to the pair distribution function.

Journal: Pharmaceutical research 20101201

Title: Metabolism and action of proteasome inhibitors in primary human hepatocytes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201

Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201

Title: Characterisation of zuclopenthixol metabolism by in vitro and therapeutic drug monitoring studies.

Journal: Acta psychiatrica Scandinavica 20101201

Title: [Probable basidiobolomycosis in a Togolese rural young successfully treated with ketoconazole].

Journal: Bulletin de la Societe de pathologie exotique (1990) 20101201

Title: High performance liquid chromatographic assay for the simultaneous determination of midazolam and ketoconazole in plasma.

Journal: Journal of pharmaceutical and biomedical analysis 20101102

Title: Azole drugs trap cytochrome P450 EryK in alternative conformational states.

Journal: Biochemistry 20101102

Title: Pharmacokinetics and pharmacodynamics of docetaxel with or without ketoconazole modulation in chemonaive breast cancer patients.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20101101

Title: Effects on plasma corticosterone levels and brain serotonin from interference with methamphetamine-induced corticosterone release in neonatal rats.

Journal: Stress (Amsterdam, Netherlands) 20101101

Title: Prediction of the intestinal first-pass metabolism of CYP3A substrates in humans using cynomolgus monkeys.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101101

Title: Synthesis and biological evaluation of N-antipyrine-4-substituted amino-3-chloromaleimide derivatives.

Journal: European journal of medicinal chemistry 20101101

Title: Regulation of the hypoxic response in Candida albicans.

Journal: Eukaryotic cell 20101101

Title: Tumor necrosis factor alpha increases P-glycoprotein expression in a BME-UV in vitro model of mammary epithelial cells.

Journal: Biopharmaceutics & drug disposition 20101101

Title: Structure and mechanism of the complex between cytochrome P4503A4 and ritonavir.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20101026

Title: Severe retention hyperkeratosis occurring with Susac syndrome.

Journal: Dermatology online journal 20101015

Title: Subcutaneous zygomycosis: report of 10 cases from two institutions in North India.

Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20101001

Title: Anticandidal effect of Ocimum sanctum essential oil and its synergy with fluconazole and ketoconazole.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20101001

Title: Synthesis and CYP24A1 inhibitory activity of (E)-2-(2-substituted benzylidene)- and 2-(2-substituted benzyl)-6-methoxy-tetralones.

Journal: European journal of medicinal chemistry 20101001

Title: Synthesis and antifungal evaluation of novel triazole derivatives as inhibitors of cytochrome P450 14alpha-demethylase.

Journal: European journal of medicinal chemistry 20101001

Title: Biorelevant media to simulate fluids in the ascending colon of humans and their usefulness in predicting intracolonic drug solubility.

Journal: Pharmaceutical research 20101001

Title: Synthesis and antimicrobial activities of novel 1H-dibenzo[a,c]carbazoles from dehydroabietic acid.

Journal: European journal of medicinal chemistry 20101001

Title: Sources of variability in ketoconazole inhibition of human cytochrome P450 3A in vitro.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20101001

Title: Retrospective analysis of the consequences of acid suppressive therapy on ketoconazole efficacy in advanced castration-resistant prostate cancer.

Journal: The Annals of pharmacotherapy 20101001

Title: [Cardiac safety of cinitapride].

Journal: Gastroenterologia y hepatologia 20101001

Title: Presumptive Nocardia spp. infection in a dog treated with cyclosporin and ketoconazole.

Journal: New Zealand veterinary journal 20101001

Title: Comparative evaluation of ketoconazole-β-cyclodextrin systems prepared by coprecipitation and kneading.

Journal: Drug discoveries & therapeutics 20101001

Title: Synthesis and evaluation of anti-Toxoplasma gondii and antimicrobial activities of thiosemicarbazides, 4-thiazolidinones and 1,3,4-thiadiazoles.

Journal: European journal of medicinal chemistry 20100901

Title: A study of cytotoxicity of novel chlorokojic acid derivatives with their antimicrobial and antiviral activities.

Journal: European journal of medicinal chemistry 20100901

Title: CYP24A1 inhibition enhances the antitumor activity of calcitriol.

Journal: Endocrinology 20100901

Title: In vitro and in vivo metabolism of a novel cannabinoid-1 receptor inverse agonist, taranabant, in rats and monkeys.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20100901

Title: Synthesis and bioassay of aminosulfonyl-1,3,4-oxadiazoles and their interconversion to 1,3,4-thiadiazoles.

Journal: European journal of medicinal chemistry 20100901

Title: Synthesis and biochemical evaluation of a range of (4-substituted phenyl)sulfonate derivatives of 4-hydroxybenzyl imidazole-based compounds as potent inhibitors of 17alpha-hydroxylase/17,20-lyase (P45017alpha) derived from rat testicular microsomes.

Journal: Bioorganic & medicinal chemistry letters 20100901

Title: Effects of drug interactions on biotransformation and antiplatelet effect of clopidogrel in vitro.

Journal: British journal of pharmacology 20100901

Title: Primary cutaneous aspergillosis.

Journal: Acta dermato-venereologica 20100901

Title: [Metabolism of 3-cyanomethyl-4-methyl-DCK, a new anti-HIV candidate, in human intestinal microsomes].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20100901

Title: New antifungal peptides. Synthesis, bioassays and initial structure prediction by CD spectroscopy.

Journal: Bioorganic & medicinal chemistry letters 20100815

Title: Replacement of imidazolyl by pyridyl in biphenylmethylenes results in selective CYP17 and dual CYP17/CYP11B1 inhibitors for the treatment of prostate cancer.

Journal: Journal of medicinal chemistry 20100812

Title: Ketoconazole in the treatment of central serous chorioretinopathy: a pilot study.

Journal: Acta ophthalmologica 20100801

Title: The post-antifungal effect (PAFE) of amphotericin B, nystatin, ketoconazole and 5-fluorocytosine and its impact on the colonization traits of Candida glabrata.

Journal: Medical mycology 20100801

Title: Ketoconazole and rifampin significantly affect the pharmacokinetics, but not the safety or QTc interval, of casopitant, a neurokinin-1 receptor antagonist.

Journal: Journal of clinical pharmacology 20100801

Title: Infantile hypercalcemia and hypercalciuria: new insights into a vitamin D-dependent mechanism and response to ketoconazole treatment.

Journal: The Journal of pediatrics 20100801

Title: Antimicrobial activity and a SAR study of some novel benzimidazole derivatives bearing hydrazone moiety.

Journal: European journal of medicinal chemistry 20100801

Title: In vitro-in vivo extrapolation predicts drug-drug interactions arising from inhibition of codeine glucuronidation by dextropropoxyphene, fluconazole, ketoconazole, and methadone in humans.

Journal: The Journal of pharmacology and experimental therapeutics 20100801

Title: Advantages of human hepatocyte-derived transformants expressing a series of human cytochrome p450 isoforms for genotoxicity examination.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20100801

Title: Differential effects of ketoconazole and primaquine on the pharmacokinetics and tissue distribution of imatinib in mice.

Journal: Anti-cancer drugs 20100801

Title: A single-dose, crossover, placebo- and moxifloxacin-controlled study to assess the effects of neratinib (HKI-272) on cardiac repolarization in healthy adult subjects.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20100801

Title: Synthesis and CYP24A1 inhibitory activity of N-(2-(1H-imidazol-1-yl)-2-phenylethyl)arylamides.

Journal: Bioorganic & medicinal chemistry 20100715

Title: Isopropylidene substitution increases activity and selectivity of biphenylmethylene 4-pyridine type CYP17 inhibitors.

Journal: Journal of medicinal chemistry 20100708

Title: Synthesis of some N-alkyl substituted urea derivatives as antibacterial and antifungal agents.

Journal: European journal of medicinal chemistry 20100701

Title: Synthesis and bioassay of pyrrolyl oxazolines and thiazolines.

Journal: European journal of medicinal chemistry 20100701

Title: Androgen blockade for the treatment of high-flow priapism.

Journal: The journal of sexual medicine 20100701

Title: Enhancement of the drug susceptibility of a triclabendazole-resistant isolate of Fasciola hepatica using the metabolic inhibitor ketoconazole.

Journal: Parasitology research 20100701

Title: Cutaneous lymphoid hyperplasia associated with Leishmania panamensis infection.

Journal: Acta dermato-venereologica 20100701

Title: Validation of a differential in situ perfusion method with mesenteric blood sampling in rats for intestinal drug interaction profiling.

Journal: Biopharmaceutics & drug disposition 20100701

Title: [Ketoconazole antagonizes the immune and gonadotropic systems in the forced swimming test in male Wistar rats].

Journal: Canadian journal of physiology and pharmacology 20100701

Title: Conazoles.

Journal: Molecules (Basel, Switzerland) 20100609

Title: Effectiveness of cabergoline in monotherapy and combined with ketoconazole in the management of Cushing's disease.

Journal: Pituitary 20100601

Title: Naftifine-analogues as anti-Trypanosoma cruzi agents.

Journal: European journal of medicinal chemistry 20100601

Title: CYP3A4 catalytic activity is induced in confluent Huh7 hepatoma cells.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20100601

Title: Increases in discontinuous rib cartilage and fused carpal bone in rat fetuses exposed to the teratogens, busulfan, acetazolamide, vitamin A, and ketoconazole.

Journal: Human & experimental toxicology 20100601

Title: A phase I clinical study of high dose ketoconazole plus weekly docetaxel for metastatic castration resistant prostate cancer.

Journal: The Journal of urology 20100601

Title: The effects of CYP2D6 and CYP3A activities on the pharmacokinetics of immediate release oxycodone.

Journal: British journal of pharmacology 20100601

Title: Trichodermaketones A-D and 7-O-methylkoninginin D from the marine fungus Trichoderma koningii.

Journal: Journal of natural products 20100528

Title: Chemical epigenetics alters the secondary metabolite composition of guttate excreted by an atlantic-forest-soil-derived Penicillium citreonigrum.

Journal: Journal of natural products 20100528

Title: Second generation analogues of the cancer drug clinical candidate tipifarnib for anti-Chagas disease drug discovery.

Journal: Journal of medicinal chemistry 20100527

Title: Determination of commonly used azole antifungals in various waters and sewage sludge using ultra-high performance liquid chromatography-tandem mass spectrometry.

Journal: Journal of chromatography. A 20100521

Title: Pharmacophore modeling strategies for the development of novel nonsteroidal inhibitors of human aromatase (CYP19).

Journal: Bioorganic & medicinal chemistry letters 20100515

Title: Pasireotide alone or with cabergoline and ketoconazole in Cushing's disease.

Journal: The New England journal of medicine 20100513

Title: Activity of ketoconazole after taxane-based chemotherapy in castration-resistant prostate cancer.

Journal: BJU international 20100501

Title: Synthesis and the selective antifungal activity of 5,6,7,8-tetrahydroimidazo[1,2-a]pyridine derivatives.

Journal: European journal of medicinal chemistry 20100501

Title: Oral fingolimod for the treatment of relapsing-remitting multiple sclerosis.

Journal: Drugs of today (Barcelona, Spain : 1998) 20100501

Title: Sex differences in subacute toxicity and hepatic microsomal metabolism of triptolide in rats.

Journal: Toxicology 20100430

Title: Structural basis of human CYP51 inhibition by antifungal azoles.

Journal: Journal of molecular biology 20100409

Title: Probing possible egress channels for multiple ligands in human CYP3A4: a molecular modeling study.

Journal: Journal of molecular modeling 20100401

Title: Genotoxicity of a freshwater cyanotoxin, cylindrospermopsin, in two human cell lines: Caco-2 and HepaRG.

Journal: Environmental and molecular mutagenesis 20100401

Title: In vitro investigation of antifungal activity of allicin alone and in combination with azoles against Candida species.

Journal: Mycopathologia 20100401

Title: Testosterone hydroxylation in bovine liver: enzyme kinetic and inhibition study.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20100401

Title: Kinetics of removal of intravenous testosterone pulses in normal men.

Journal: European journal of endocrinology 20100401

Title: An eco-friendly synthesis and antimicrobial activities of dihydro-2H-benzo- and naphtho-1,3-oxazine derivatives.

Journal: European journal of medicinal chemistry 20100401

Title: In vitro and in vivo evaluation of oral tablet formulations prepared with ketoconazole and hydroxypropyl-beta-cyclodextrin.

Journal: Drug delivery 20100401

Title: Potent and selective inhibition of human cytochrome P450 3A4 by seco-pancratistatin structural analogs.

Journal: Bioorganic & medicinal chemistry letters 20100401

Title: Predictions of metabolic drug-drug interactions using physiologically based modelling: Two cytochrome P450 3A4 substrates coadministered with ketoconazole or verapamil.

Journal: Clinical pharmacokinetics 20100401

Title: Effects of ketoconazole on the biodistribution and metabolism of [11C]loperamide and [11C]N-desmethyl-loperamide in wild-type and P-gp knockout mice.

Journal: Nuclear medicine and biology 20100401

Title: [Malassezia folliculitis: 21 cases].

Journal: Annales de dermatologie et de venereologie 20100401

Title: Pyrenochaeta keratinophila sp. nov., isolated from an ocular infection in Spain.

Journal: Revista iberoamericana de micologia 20100331

Title: Phase I clinical trial of the CYP17 inhibitor abiraterone acetate demonstrating clinical activity in patients with castration-resistant prostate cancer who received prior ketoconazole therapy.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100320

Title: Phase 1 pharmacokinetic and drug-interaction study of dasatinib in patients with advanced solid tumors.

Journal: Cancer 20100315

Title: Response to azolic antifungal agents for treating feline sporotrichosis.

Journal: The Veterinary record 20100306

Title: Current concepts in systemic and topical therapy for superficial mycoses.

Journal: Clinics in dermatology 20100304

Title: Intralesional sodium stibogluconate alone or its combination with either intramuscular sodium stibogluconate or oral ketoconazole in the treatment of localized cutaneous leishmaniasis: a comparative study.

Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20100301

Title: Potent in vitro inhibition of CYP3A4 and P-glycoprotein by Rhodiola rosea.

Journal: Planta medica 20100301

Title: Synthesis, characterization and biocidal activity of new organotin complexes of 2-(3-oxocyclohex-1-enyl)benzoic acid.

Journal: European journal of medicinal chemistry 20100301

Title: Antimicrobial study of newly synthesized 6-substituted indolo[1,2-c]quinazolines.

Journal: European journal of medicinal chemistry 20100301

Title: Pulmonary toxicity and metabolic activation of dauricine in CD-1 mice.

Journal: The Journal of pharmacology and experimental therapeutics 20100301

Title: Composition optimization and stability testing of a parenteral antifungal solution based on a ternary solvent system.

Journal: AAPS PharmSciTech 20100301

Title: Comparative evaluation of ketoconazole tablet and topical ketoconazole 2% in orabase in treatment of Candida-infected denture stomatitis.

Journal: The journal of contemporary dental practice 20100301

Title: Effect of ketoconazole on the pharmacokinetics of udenafil in healthy Korean subjects.

Journal: British journal of clinical pharmacology 20100301

Title: Absorption barriers in the rat intestinal mucosa: 2. Application of physiologically based mathematical models to quantify mechanisms of drug permeation and metabolism.

Journal: Journal of pharmaceutical sciences 20100201

Title: Quantitative prediction and clinical observation of a CYP3A inhibitor-based drug-drug interactions with MLN3897, a potent C-C chemokine receptor-1 antagonist.

Journal: The Journal of pharmacology and experimental therapeutics 20100201

Title: Ketoconazole enantiomer for the treatment of diabetes mellitus.

Journal: Expert opinion on investigational drugs 20100201

Title: Use of antifungal agents for oral candidiasis: results of a national survey.

Journal: International journal of dental hygiene 20100201

Title: Sulfonamide-1,2,4-thiadiazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies.

Journal: Chemical & pharmaceutical bulletin 20100201

Title: The pharmacokinetics of ketoconazole and its effects on the pharmacokinetics of midazolam and fentanyl in dogs.

Journal: Journal of veterinary pharmacology and therapeutics 20100201

Title: Cutaneous malasseziasis: four case reports of atypical dermatitis and onychomycosis caused by Malassezia.

Journal: International journal of dermatology 20100201

Title: Adrenocorticotrophic hormone (ACTH) responsiveness to ghrelin increases after 6 months of ketoconazole use in patients with Cushing's disease: comparison with GH-releasing peptide-6 (GHRP-6).

Journal: Clinical endocrinology 20100101

Title: In young men, a moderate inhibition of testosterone synthesis capacity is only partly compensated by increased activity of the pituitary and the hypothalamus.

Journal: Clinical endocrinology 20100101

Title: Synergistic anti-candidal activity of tetrandrine on ketoconazole: an experimental study.

Journal: Planta medica 20100101

Title: Identification of the human cytochrome P450 enzymes involved in the two oxidative steps in the bioactivation of clopidogrel to its pharmacologically active metabolite.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20100101

Title: The application of in vitro technologies to study the metabolism of the androgenic/anabolic steroid stanozolol in the equine.

Journal: Steroids 20100101

Title: Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs.

Journal: Bioorganic & medicinal chemistry 20100101

Title: Screening of antimycotics in Swedish sewage treatment plants--waters and sludge.

Journal: Water research 20100101

Title: CYP3A catalyses schizandrin biotransformation in human, minipig and rat liver microsomes.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20100101

Title: Candida albicans enhances experimental hepatic melanoma metastasis.

Journal: Clinical & experimental metastasis 20100101

Title: Esthesioneuroblastoma (Olfactory Neuroblastoma) with Ectopic ACTH Syndrome: a multidisciplinary case presentation from the Joan Karnell cancer center of Pennsylvania Hospital.

Journal: The oncologist 20100101

Title: Hormonal therapy for acne: why not as first line therapy? facts and controversies.

Journal: Clinics in dermatology 20100101

Title: [Acquired pigmented lesion of the foot].

Journal: Annales de dermatologie et de venereologie 20100101

Title: Everolimus versus azathioprine in a cyclosporine and ketoconazole-based immunosuppressive therapy in kidney transplant: 3-year follow-up of an open-label, prospective, cohort, comparative clinical trial.

Journal: Transplantation proceedings 20100101

Title: Effectiveness and cost of replacing a calcineurin inhibitor with sirolimus to slow the course of chronic kidney disease in renal allografts.

Journal: Transplantation proceedings 20100101

Title: [Echinococcosis complicated by paecilomycosis].

Journal: Meditsinskaia parazitologiia i parazitarnye bolezni 20100101

Title: Medical therapy of Cushing's disease: where are we now?

Journal: Frontiers of hormone research 20100101

Title: Diagnostic and therapeutic challenge in the management of a patient with ectopic adrenocorticotropin secretion.

Journal: Journal of endocrinological investigation 20100101

Title: The sensitivity and specificity of potassium hydroxide smear and fungal culture relative to clinical assessment in the evaluation of tinea pedis: a pooled analysis.

Journal: Dermatology research and practice 20100101

Title: Colletotrichum graminicola keratitis: first case report from India.

Journal: Indian journal of ophthalmology 20100101

Title: Management of diabetes mellitus in Cushing's syndrome.

Journal: Neuroendocrinology 20100101

Title: Management of dyslipidemia in Cushing's syndrome.

Journal: Neuroendocrinology 20100101

Title: Medical treatment of Cushing's syndrome: adrenal-blocking drugs and ketaconazole.

Journal: Neuroendocrinology 20100101

Title: Evaluation of terfenadine and ketoconazole-induced QT prolongation in conscious telemetered guinea pigs.

Journal: Pharmacological reports : PR 20100101

Title: High-performance thin-layer chromatographic determination of ketoconazole in pharmaceutical formulations.

Journal: Journal of cosmetic science 20100101

Title: A noninferiority clinical trial comparing fluconazole and ketoconazole in combination with cephalexin for the treatment of dogs with Malassezia dermatitis.

Journal: Veterinary therapeutics : research in applied veterinary medicine 20100101

Title: Sporothrix schenckii associated with armadillo hunting in Southern Brazil: epidemiological and antifungal susceptibility profiles.

Journal: Revista da Sociedade Brasileira de Medicina Tropical 20100101

Title: Use of granisetron transdermal system in the prevention of chemotherapy-induced nausea and vomiting: a review.

Journal: Cancer management and research 20100101

Title: Novel medical treatment of pituitary adrenocorticotropic hormone-dependent hypercortisolism: a case study.

Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20100101

Title: Childhood acute generalized exanthematous pustulosis induced by oral ketoconazole.

Journal: Acta dermatovenerologica Croatica : ADC 20100101

Title: Antioxidant and antimicrobial activity of some lichen species.

Journal: Mikrobiologiia 20100101

Title: [White piedra in a pediatric patient: a case report].

Journal: Revista iberoamericana de micologia 20091231

Title: Rapid LC-MS drug metabolite profiling using microsomal enzyme bioreactors in a parallel processing format.

Journal: Analytical chemistry 20091215

Title: Simultaneous determination of five systemic azoles in plasma by high-performance liquid chromatography with ultraviolet detection.

Journal: Journal of pharmaceutical and biomedical analysis 20091205

Title: Synergistic anticandidal activity of xanthorrhizol in combination with ketoconazole or amphotericin B.

Journal: FEMS yeast research 20091201

Title: Inhibition and stimulation of intestinal and hepatic CYP3A activity: studies in humanized CYP3A4 transgenic mice using triazolam.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20091201

Title: Side chain azasteroids and thiasteroids as sterol methyltransferase inhibitors in ergosterol biosynthesis.

Journal: Bioorganic & medicinal chemistry 20091201

Title: Synthesis and biological activities of new substituted thiazoline-quinoline derivatives.

Journal: Acta pharmaceutica (Zagreb, Croatia) 20091201

Title: Drugs in the medical treatment of Cushing's syndrome.

Journal: Expert opinion on emerging drugs 20091201

Title: The effects of ketoconazole and rifampicin on the pharmacokinetics of mirodenafil in healthy Korean male volunteers: an open-label, one-sequence, three-period, three-treatment crossover study.

Journal: Clinical therapeutics 20091201

Title: Rhabdomyomatous mesenchymal hamartoma: clinical overview and report of a case with spontaneous regression.

Journal: The West Indian medical journal 20091201

Title: Strategy of accelerated method development for high-throughput bioanalytical assays using ultra high-performance liquid chromatography coupled with mass spectrometry.

Journal: Analytical chemistry 20091115

Title: Phase II study of androgen synthesis inhibition with ketoconazole, hydrocortisone, and dutasteride in asymptomatic castration-resistant prostate cancer.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20091115

Title: Influence of quinidine, cimetidine, and ketoconazole on the enantioselective pharmacokinetics and metabolism of metoprolol in rats.

Journal: Chirality 20091101

Title: Synthesis of some novel pyrazolo[3,4-b]pyridine and pyrazolo[3,4-d]pyrimidine derivatives bearing 5,6-diphenyl-1,2,4-triazine moiety as potential antimicrobial agents.

Journal: European journal of medicinal chemistry 20091101

Title: Synthesis, antimicrobial and antioxidant activities of substituted pyrazoles, isoxazoles, pyrimidine and thioxopyrimidine derivatives.

Journal: European journal of medicinal chemistry 20091101

Title: Roles of different CYP enzymes in the formation of specific fluvastatin metabolites by human liver microsomes.

Journal: Basic & clinical pharmacology & toxicology 20091101

Title: Different effects of ketoconazole on the stereoselective first-pass metabolism of R/S-verapamil in the intestine and the liver: important for the mechanistic understanding of first-pass drug-drug interactions.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20091101

Title: Partial restoration of GH responsiveness to ghrelin in Cushing's disease after 6 months of ketoconazole treatment: comparison with GHRP-6 and GHRH.

Journal: European journal of endocrinology 20091101

Title: Synthesis, Raman, FT-IR, NMR spectroscopic characterization, antimicrobial activity, cytotoxicity and DNA binding of new mixed aza-oxo-thia macrocyclic compounds.

Journal: European journal of medicinal chemistry 20091101

Title: Evaluation of drug-polymer miscibility in amorphous solid dispersion systems.

Journal: Pharmaceutical research 20091101

Title: 5-Nitrofuranes and 5-nitrothiophenes with anti-Trypanosoma cruzi activity and ability to accumulate squalene.

Journal: Bioorganic & medicinal chemistry 20091101

Title: Deactivation of anti-cancer drug letrozole to a carbinol metabolite by polymorphic cytochrome P450 2A6 in human liver microsomes.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20091101

Title: In vitro antimalarial interactions between mefloquine and cytochrome P450 inhibitors.

Journal: Acta tropica 20091001

Title: Superficial distribution and identification of antifungal/antimicrobial agents on a modified tissue conditioner by SEM-EDS microanalysis: a preliminary study.

Journal: Journal of prosthodontics : official journal of the American College of Prosthodontists 20091001

Title: Ketoconazole-induced JNK phosphorylation and subsequent cell death via apoptosis in human osteosarcoma cells.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20091001

Title: Ketoconazole and prednisone to prevent recurrent ischemic priapism.

Journal: The Journal of urology 20091001

Title: Structure-activity studies on seco-pancratistatin analogs: potent inhibitors of human cytochrome P450 3A4.

Journal: Bioorganic & medicinal chemistry letters 20091001

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology 20091001

Title: Biliary excretion of technetium-99m-sestamibi in wild-type dogs and in dogs with intrinsic (ABCB1-1Delta mutation) and extrinsic (ketoconazole treated) P-glycoprotein deficiency.

Journal: Journal of veterinary pharmacology and therapeutics 20091001

Title: Activity of dutasteride plus ketoconazole in castration-refractory prostate cancer after progression on ketoconazole alone.

Journal: Clinical genitourinary cancer 20091001

Title: In vitro and in vivo evaluation of the inhibition potential of risperidone toward clozapine biotransformation.

Journal: British journal of clinical pharmacology 20091001

Title: A novel class of highly potent multidrug resistance reversal agents: disubstituted adamantyl derivatives.

Journal: Bioorganic & medicinal chemistry letters 20090915

Title: Transfer of rolf S3-S4 linker to HERG eliminates activation gating but spares inactivation.

Journal: Biophysical journal 20090902

Title: The amino acid residues of transmembrane helix 5 of multidrug resistance protein CaCdr1p of Candida albicans are involved in substrate specificity and drug transport.

Journal: Biochimica et biophysica acta 20090901

Title: The arachidonic acid epoxygenase is a component of the signaling mechanisms responsible for VEGF-stimulated angiogenesis.

Journal: Archives of biochemistry and biophysics 20090901

Title: Prednisone reduces ketoconazole-induced skeletal defects in rat fetuses.

Journal: Archives of toxicology 20090901

Title: In vitro synergistic effects of antituberculous drugs plus antifungals against Coccidioides posadasii.

Journal: International journal of antimicrobial agents 20090901

Title: Infectious keratitis caused by Aspergillus tubingensis.

Journal: Cornea 20090901

Title: Aetiological treatment with itraconazole or ketoconazole in individuals with Trypanosoma cruzi/HIV co-infection.

Journal: Annals of tropical medicine and parasitology 20090901

Title: The effect on sotrastaurin pharmacokinetics of strong CYP3A inhibition by ketoconazole.

Journal: British journal of clinical pharmacology 20090901

Title: Inhibitory effects of ketoconazole, cimetidine and erythromycin on hepatic CYP3A activities in cats.

Journal: The Journal of veterinary medical science 20090901

Title: Synthesis and biochemical evaluation of a range of sulfonated derivatives of 4-hydroxybenzyl imidazole as highly potent inhibitors of rat testicular 17alpha-hydroxylase/17,20-lyase (P-450(17alpha)).

Journal: Bioorganic & medicinal chemistry letters 20090815

Title: Electron paramagnetic resonance method for the quantitative assay of ketoconazole in pharmaceutical preparations.

Journal: Analytical chemistry 20090815

Title: Differential effect of Shenmai injection, a herbal preparation, on the cytochrome P450 3A-mediated 1'-hydroxylation and 4-hydroxylation of midazolam.

Journal: Chemico-biological interactions 20090814

Title: Identification and chromosomal localization of one locus of Leishmania (L.) major related with resistance to itraconazole.

Journal: Parasitology research 20090801

Title: Spondylodiscitis due to an emergent fungal pathogen: Blastoschizomyces capitatus, a case report and review of the literature.

Journal: Rheumatology international 20090801

Title: Mono and bis-6-arylbenzimidazo[1,2-c]quinazolines: a new class of antimicrobial agents.

Journal: European journal of medicinal chemistry 20090801

Title: Synthesis and antimultidrug resistance evaluation of icariin and its derivatives.

Journal: Bioorganic & medicinal chemistry letters 20090801

Title: About the role of enantioselective selector-selectand interactions and the mobilities of diastereomeric associates in enantiomer separations using CE.

Journal: Electrophoresis 20090801

Title: Dermatomycosis in a pet inland bearded dragon (Pogona vitticeps) caused by a Chrysosporium species related to Nannizziopsis vriesii.

Journal: Veterinary dermatology 20090801

Title: Metabolism of loratadine and further characterization of its in vitro metabolites.

Journal: Drug metabolism letters 20090801

Title: Revisiting the metabolism of ketoconazole using accurate mass.

Journal: Drug metabolism letters 20090801

Title: Side chain flexibilities in the human ether-a-go-go related gene potassium channel (hERG) together with matched-pair binding studies suggest a new binding mode for channel blockers.

Journal: Journal of medicinal chemistry 20090723

Title: Hypokalemia, metabolic alkalosis, and hypertension in a lung cancer patient.

Journal: Kidney international 20090701

Title: Nonlinear stereoselective pharmacokinetics of ketoconazole in rat after administration of racemate.

Journal: Chirality 20090701

Title: In vitro inhibition of CYP3A4 by herbal remedies frequently used by cancer patients.

Journal: Phytotherapy research : PTR 20090701

Title: Novel CYP17 inhibitors: synthesis, biological evaluation, structure-activity relationships and modelling of methoxy- and hydroxy-substituted methyleneimidazolyl biphenyls.

Journal: European journal of medicinal chemistry 20090701

Title: Limited sampling strategy in rats to predict the inhibited activities of hepatic CYP3A.

Journal: Laboratory animals 20090701

Title: Steroidogenesis inhibitors alter but do not eliminate androgen synthesis mechanisms during progression to castration-resistance in LNCaP prostate xenografts.

Journal: The Journal of steroid biochemistry and molecular biology 20090701

Title: Regioselective synthesis and biological evaluation of bis(indolyl)methane derivatized 1,4-disubstituted 1,2,3-bistriazoles as anti-infective agents.

Journal: Bioorganic & medicinal chemistry letters 20090701

Title: Single-center experience with cyclosporine for treatment of idiopathic minimal change nephrotic syndrome in children.

Journal: Iranian journal of kidney diseases 20090701

Title: In vitro response of cutaneous mycosis fungal agents to the most widely used systemic antifungals in dermatology.

Journal: Anais brasileiros de dermatologia 20090701

Title: Drug-drug interaction prediction assessment.

Journal: Journal of biopharmaceutical statistics 20090701

Title: Cytotoxicity of ginkgolic acid in HepG2 cells and primary rat hepatocytes.

Journal: Toxicology letters 20090622

Title: Selective cytochrome P450 3A4 inhibitory activity of Amaryllidaceae alkaloids.

Journal: Bioorganic & medicinal chemistry letters 20090615

Title: An inhibition study of beauvericin on human and rat cytochrome P450 enzymes and its pharmacokinetics in rats.

Journal: Journal of enzyme inhibition and medicinal chemistry 20090601

Title: Neurocryptococcosis in a 10-year-old immunocompetent girl.

Journal: Acta neurochirurgica 20090601

Title: Evaluation of drug-drug interactions with fesoterodine.

Journal: European journal of clinical pharmacology 20090601

Title: CYP3A5*1/*3 genotype influences the blood concentration of tacrolimus in response to metabolic inhibition by ketoconazole.

Journal: Pharmacogenetics and genomics 20090601

Title: Effect of ketoconazole on the pharmacokinetic profile of ambrisentan.

Journal: Journal of clinical pharmacology 20090601

Title: Growth inhibitory action of ebselen on fluconazole-resistant Candida albicans: role of the plasma membrane H+-ATPase.

Journal: Microbial drug resistance (Larchmont, N.Y.) 20090601

Title: Bulky 1,4-benzoxazine derivatives with antifungal activity.

Journal: Bioorganic & medicinal chemistry 20090601

Title: Therapies for pediatric seborrheic dermatitis.

Journal: Pediatric annals 20090601

Title: Randomised controlled trial of the treatment of pastern dermatitis with a formulation containing kunzea oil.

Journal: The Veterinary record 20090516

Title: Synthesis and bioassay of a new class of heterocycles pyrrolyl oxadiazoles/thiadiazoles/triazoles.

Journal: European journal of medicinal chemistry 20090501

Title: Synthesis and anti-microbial screening of some Schiff bases of 3-amino-6,8-dibromo-2-phenylquinazolin-4(3H)-ones.

Journal: European journal of medicinal chemistry 20090501

Title: Synthesis, antimicrobial and cytotoxic activities of some 5-arylidene-4-thioxo-thiazolidine-2-ones.

Journal: European journal of medicinal chemistry 20090501

Title: Synthesis, antimicrobial evaluation and QSAR study of some 3-hydroxypyridine-4-one and 3-hydroxypyran-4-one derivatives.

Journal: European journal of medicinal chemistry 20090501

Title: Design, synthesis, and biological evaluation of novel triazole derivatives as inhibitors of cytochrome P450 14alpha-demethylase.

Journal: European journal of medicinal chemistry 20090501

Title: Electronic, Raman and FT-IR spectral investigations of the charge transfer interactions between ketoconazole and povidone drugs with iodine.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20090501

Title: Novel secondary hormonal therapy in advanced prostate cancer: an update.

Journal: Current opinion in urology 20090501

Title: Identification of quinone methide metabolites of dauricine in human liver microsomes and in rat bile.

Journal: Chemical research in toxicology 20090501

Title: Antimicrobial ambiguine isonitriles from the cyanobacterium Fischerella ambigua.

Journal: Journal of natural products 20090501

Title: Ketoconazole retains activity in patients with docetaxel-refractory prostate cancer.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20090501

Title: New acyclic nucleosides analogues as potential analgesic, anti-inflammatory, anti-oxidant and anti-microbial derived from pyrimido[4,5-b]quinolines.

Journal: European journal of medicinal chemistry 20090401

Title: Contact allergy to ketoconazole cross-sensitive to miconazole.

Journal: Clinical and experimental dermatology 20090401

Title: In vitro activities of retigeric acid B alone and in combination with azole antifungal agents against Candida albicans.

Journal: Antimicrobial agents and chemotherapy 20090401

Title: Exploratory study on the clinical and mycological effectiveness of a herbal medicinal product from Solanum chrysotrichum in patients with Candida yeast-associated vaginal infection.

Journal: Planta medica 20090401

Title: Relative contributions of the Candida albicans ABC transporters Cdr1p and Cdr2p to clinical azole resistance.

Journal: Antimicrobial agents and chemotherapy 20090401

Title: Effect of different durations of ketoconazole dosing on the single-dose pharmacokinetics of midazolam: shortening the paradigm.

Journal: Journal of clinical pharmacology 20090401

Title: [Treatment of Cushing's disease with ketoconazole].

Journal: Anales de pediatria (Barcelona, Spain : 2003) 20090401

Title: In vitro metabolism and inhibitory effects of pranlukast in human liver microsomes.

Journal: Biological & pharmaceutical bulletin 20090401

Title: Effects of ketoconazole and carbamazepine on lapatinib pharmacokinetics in healthy subjects.

Journal: British journal of clinical pharmacology 20090401

Title: Ketoconazole allergy.

Journal: Clinics (Sao Paulo, Brazil) 20090401

Title: [Enzyme kinetics of ligustilide metabolism in rat liver microsomes].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20090401

Title: Direct antifungal susceptibility testing of positive Candida blood cultures by sensititre YeastOne.

Journal: The new microbiologica 20090401

Title: Steroidogenesis-disrupting compounds can be effectively studied for major fertility-related endpoints using in vitro cultured mouse follicles.

Journal: Toxicology letters 20090328

Title: Rational modification of a candidate cancer drug for use against Chagas disease.

Journal: Journal of medicinal chemistry 20090326

Title: Design, synthesis, and biological evaluation of novel 1-(1H-1,2,4-triazole-1-yl)-2-(2,4-difluorophenyl)-3-substituted benzylamino-2-propanols.

Journal: Bioorganic & medicinal chemistry letters 20090315

Title: Relation between lipophilicity of alkyl gallates and antifungal activity against yeasts and filamentous fungi.

Journal: Bioorganic & medicinal chemistry letters 20090315

Title: Modulation of the antifungal activity of new medicinal plant extracts active on Candida glabrata by the major transporters and regulators of the pleiotropic drug-resistance network in Saccharomyces cerevisiae.

Journal: Microbial drug resistance (Larchmont, N.Y.) 20090301

Title: Pharmacological interactions of anti-microbial agents in odontology.

Journal: Medicina oral, patologia oral y cirugia bucal 20090301

Title: Quantitative evaluation of pharmacokinetic inhibition of CYP3A substrates by ketoconazole: a simulation study.

Journal: Journal of clinical pharmacology 20090301

Title: The need for multiple doses of 400 mg ketoconazole as a precipitant inhibitor of a CYP3A substrate in an in vivo drug-drug interaction study.

Journal: Journal of clinical pharmacology 20090301

Title: A single-center, open-label, one-sequence study of dalcetrapib coadministered with ketoconazole, and an in vitro study of the S-methyl metabolite of dalcetrapib.

Journal: Clinical therapeutics 20090301

Title: Flexible structure of cytochrome P450: promiscuity of ligand binding in the CYP3A4 heme pocket.

Journal: Anticancer research 20090301

Title: Ketoconazole treatment for Cushing syndrome in McCune-Albright syndrome.

Journal: The Journal of pediatrics 20090301

Title: Aqueous solvent system for the solubilization of azole compounds.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090215

Title: Rhinosporidiosis in a dog native to the UK.

Journal: The Veterinary record 20090214

Title: CYP1A1 induction and CYP3A4 inhibition by the fungicide imazalil in the human intestinal Caco-2 cells-comparison with other conazole pesticides.

Journal: Toxicology letters 20090210

Title: Clearance and clearance inhibition of the HIV-1 protease inhibitors ritonavir and saquinavir in sandwich-cultured rat hepatocytes and rat microsomes.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20090201

Title: Synthesis and antifungal activity of 1,2,3-triazole containing fluconazole analogues.

Journal: Bioorganic & medicinal chemistry letters 20090201

Title: Ketoconazole increases fingolimod blood levels in a drug interaction via CYP4F2 inhibition.

Journal: Journal of clinical pharmacology 20090201

Title: A new probabilistic rule for drug-dug interaction prediction.

Journal: Journal of pharmacokinetics and pharmacodynamics 20090201

Title: Inhibition of cytochrome P450 activity enhances the systemic availability of triclabendazole metabolites in sheep.

Journal: Journal of veterinary pharmacology and therapeutics 20090201

Title: Pharmacokinetic interaction between efavirenz and ketoconazole in rats.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20090201

Title: Effects of oral posaconazole on the pharmacokinetic properties of oral and intravenous midazolam: a phase I, randomized, open-label, crossover study in healthy volunteers.

Journal: Clinical therapeutics 20090201

Title: Clinical practice. Seborrheic dermatitis.

Journal: The New England journal of medicine 20090122

Title: Novel non-active site inhibitor of Cryptosporidium hominis TS-DHFR identified by a virtual screen.

Journal: Bioorganic & medicinal chemistry letters 20090115

Title: Synthesis, trypanocidal activity and docking studies of novel quinoxaline-N-acylhydrazones, designed as cruzain inhibitors candidates.

Journal: Bioorganic & medicinal chemistry 20090115

Title: Synthesis, Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of mixed aza-oxo-thia macrocyclic compounds.

Journal: European journal of medicinal chemistry 20090101

Title: An open, randomized, prospective, comparative study of topical pimecrolimus 1% cream and topical ketoconazole 2% cream in the treatment of seborrheic dermatitis.

Journal: The Journal of dermatological treatment 20090101

Title: Decreased oral absorption of cyclosporine A after liver ischemia-reperfusion injury in rats: the contribution of CYP3A and P-glycoprotein to the first-pass metabolism in intestinal epithelial cells.

Journal: The Journal of pharmacology and experimental therapeutics 20090101

Title: Effect of oral ketoconazole on oral and intravenous pharmacokinetics of simvastatin and its acid in cynomolgus monkeys.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20090101

Title: Fungistatic effects of optical brightener 220 against Trichophyton tonsurans, Aspergillus fumigatus and Candida albicans.

Journal: The Journal of dermatological treatment 20090101

Title: Assessment of the CYP3A-mediated drug interaction potential of anacetrapib, a potent cholesteryl ester transfer protein (CETP) inhibitor, in healthy volunteers.

Journal: Journal of clinical pharmacology 20090101

Title: Inhibition of CYP3A4 expression by ketoconazole is mediated by the disruption of pregnane X receptor, steroid receptor coactivator-1, and hepatocyte nuclear factor 4alpha interaction.

Journal: Pharmacogenetics and genomics 20090101

Title: Etomidate infusion in the critical care setting for suppressing the acute phase of Cushing's syndrome.

Journal: Anesthesia and analgesia 20090101

Title: Glucocorticoid inhibition in the treatment of depression: can we think outside the endocrine hypothalamus?

Journal: Depression and anxiety 20090101

Title: A study to evaluate the efficacy and safety of oral fluconazole in the treatment of tinea versicolor.

Journal: Mymensingh medical journal : MMJ 20090101

Title: [Fungicidal activity of liranaftate against dermatophytes].

Journal: Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology 20090101

Title: In vitro susceptibility testing of dermatophytes isolated in Goiania, Brazil, against five antifungal agents by broth microdilution method.

Journal: Revista do Instituto de Medicina Tropical de Sao Paulo 20090101

Title: Alterations in growth and branching of Neurospora crassa caused by sub-inhibitory concentrations of antifungal agents.

Journal: Revista Argentina de microbiologia 20090101

Title: Tinea capitis due to Trichophyton soudanense in Chicago, Illinois: report of a case.

Journal: Pediatric dermatology 20090101

Title: Bioequivalence studies and sugar-based excipients effects on the properties of new generic ketoconazole tablets formulations and stability evaluation by using direct compression method.

Journal: Pharmaceutical development and technology 20090101

Title: High-throughput fluorescence assay of cytochrome P450 3A4.

Journal: Nature protocols 20090101

Title: Determination of ketoconazole in capsules by high-performance liquid chromatography and microbiological assay.

Journal: Journal of AOAC International 20090101

Title: Two-year experience with tacrolimus in renal transplantation after late conversion from cyclosporine therapy.

Journal: Transplantation proceedings 20090101

Title: Ketoconazole inhibits the growth and development of Ichthyophonus sp. (Mesomycetozoa) in vitro.

Journal: The Journal of eukaryotic microbiology 20090101

Title: [Guidelines for diagnosis and treatment of mucocutaneous candidiasis].

Journal: Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology 20090101

Title: Prediction of drug-drug interactions based on time-dependent inhibition from high throughput screening of cytochrome P450 3A4 inhibition.

Journal: Drug metabolism and pharmacokinetics 20090101

Title: Effect of the CYP3A inhibitor ketoconazole on the pharmacokinetics and pharmacodynamics of bortezomib in patients with advanced solid tumors: a prospective, multicenter, open-label, randomized, two-way crossover drug-drug interaction study.

Journal: Clinical therapeutics 20090101

Title: [Nizoral - an effective and affordable drug to treat vaginal candidiasis ].

Journal: Akusherstvo i ginekologiia 20090101

Title: In vivo active aldosterone synthase inhibitors with improved selectivity: lead optimization providing a series of pyridine substituted 3,4-dihydro-1H-quinolin-2-one derivatives.

Journal: Journal of medicinal chemistry 20081225

Title: Phase III trial of androgen ablation with or without three cycles of systemic chemotherapy for advanced prostate cancer.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081220

Title: Use of ketoconazole to treat dogs with pituitary-dependent hyperadrenocorticism: 48 cases (1994-2007).

Journal: Journal of the American Veterinary Medical Association 20081215

Title: Biopositive effects of low-dose UVB on epidermis: coordinate upregulation of antimicrobial peptides and permeability barrier reinforcement.

Journal: The Journal of investigative dermatology 20081201

Title: The combination of chemical and antibody inhibitors for superior P450 3A inhibition in reaction phenotyping studies.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20081201

Title: Effects of an ergosterol synthesis inhibitor on gene transcription of terpenoid biosynthesis in Blakeslea trispora.

Journal: Current microbiology 20081201

Title: Confirmation that cytochrome P450 2C8 (CYP2C8) plays a minor role in (S)-(+)- and (R)-(-)-ibuprofen hydroxylation in vitro.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20081201

Title: A double transgenic mouse model expressing human pregnane X receptor and cytochrome P450 3A4.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20081201

Title: Interindividual variation in relative CYP1A2/3A4 phenotype influences susceptibility of clozapine oxidation to cytochrome P450-specific inhibition in human hepatic microsomes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20081201

Title: Bone-targeted therapy: phase II study of strontium-89 in combination with alternating weekly chemohormonal therapies for patients with advanced androgen-independent prostate cancer.

Journal: American journal of clinical oncology 20081201

Title: Susceptibility to voriconazole, fluconazole, and ketoconazole of yeast isolated from patients with hematological malignancies.

Journal: Journal of chemotherapy (Florence, Italy) 20081201

Title: Presystemic elimination of budesonide in man when administered locally at different levels in the gut, with and without local inhibition by ketoconazole.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20081115

Title: Comparative efficacy and tolerability of Ketomousse (ketoconazole foam 1%) and ketoconazole cream 2% in the treatment of pityriasis versicolor: results of a prospective, multicentre, randomised study.

Journal: Mycoses 20081101

Title: Widespread, chronic, and fluconazole-resistant Trichophyton rubrum infection in an immunocompetent patient.

Journal: Mycoses 20081101

Title: Effect of commonly used herbicides on the virulence factor CDR1 in Candida albicans.

Journal: Environmental toxicology and chemistry 20081101

Title: Hypocortisolemic clamp unmasks jointly feedforward- and feedback-dependent control of overnight ACTH secretion.

Journal: European journal of endocrinology 20081101

Title: Effect of single and repeated doses of ketoconazole on the pharmacokinetics of roflumilast and roflumilast N-oxide.

Journal: Journal of clinical pharmacology 20081101

Title: Pharmacokinetics of the oral direct renin inhibitor aliskiren in combination with digoxin, atorvastatin, and ketoconazole in healthy subjects: the role of P-glycoprotein in the disposition of aliskiren.

Journal: Journal of clinical pharmacology 20081101

Title: Re: Oral ketoconazole for prevention of postoperative penile erection: a placebo controlled, randomized, double-blind trial: B. J. DeCastro, R. A. Costabile, L. P. McMann and A. C. Peterson. J Urol 2008; 179: 1930-1932.

Journal: The Journal of urology 20081101

Title: 1alpha,25-Dihydroxyvitamin D hydroxylase in adipocytes.

Journal: The Journal of steroid biochemistry and molecular biology 20081101

Title: Human CYP3A4-introduced HepG2 cells: in vitro screening system of new chemicals for the evaluation of CYP3A4-inhibiting activity.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20081101

Title: Monodictyochromes A and B, dimeric xanthone derivatives from the marine algicolous fungus Monodictys putredinis.

Journal: Journal of natural products 20081101

Title: In vitro CYP3A4 metabolism: inhibition by Echinacea purpurea and choice of substrate for the evaluation of herbal inhibition.

Journal: Basic & clinical pharmacology & toxicology 20081101

Title: Influence of quinidine, fluvoxamine, and ketoconazole on the enantioselective pharmacokinetics of citalopram in rats.

Journal: Canadian journal of physiology and pharmacology 20081101

Title: Histopathological effect of ketoconazole on rat placenta.

Journal: The Journal of veterinary medical science 20081101

Title: [Mixed vaginitis prevalence in Latin-American women, according to physician perception. Preference, effectiveness and security of clindamycin plus ketoconazole].

Journal: Ginecologia y obstetricia de Mexico 20081101

Title: Activation of the proopiomelanocortin gene with ketoconazole as a treatment for Parkinson's disease: a new hypothesis.

Journal: Annals of the New York Academy of Sciences 20081101

Title: Ketoconazole increases the plasma levels of ivermectin in sheep.

Journal: Veterinary parasitology 20081020

Title: Novel aldosterone synthase inhibitors with extended carbocyclic skeleton by a combined ligand-based and structure-based drug design approach.

Journal: Journal of medicinal chemistry 20081009

Title: Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.

Journal: Journal of medicinal chemistry 20081009

Title: Condensed bridgehead nitrogen heterocyclic system: synthesis and pharmacological activities of 1,2,4-triazolo-[3,4-b]-1,3,4-thiadiazole derivatives of ibuprofen and biphenyl-4-yloxy acetic acid.

Journal: European journal of medicinal chemistry 20081001

Title: Effect of coadministration of ketoconazole, a strong CYP3A4 inhibitor, on pharmacokinetics and tolerability of motesanib diphosphate (AMG 706) in patients with advanced solid tumors.

Journal: Investigational new drugs 20081001

Title: Maraviroc: in vitro assessment of drug-drug interaction potential.

Journal: British journal of clinical pharmacology 20081001

Title: Differential azole antifungal efficacies contrasted using a Saccharomyces cerevisiae strain humanized for sterol 14 alpha-demethylase at the homologous locus.

Journal: Antimicrobial agents and chemotherapy 20081001

Title: Inhibition of hERG channel trafficking: an under-explored mechanism for drug-induced QT prolongation.

Journal: ChemMedChem 20081001

Title: Management of recurrent and refractory Cushing disease.

Journal: Nature clinical practice. Endocrinology & metabolism 20081001

Title: Medical treatments for male and female pattern hair loss.

Journal: Journal of the American Academy of Dermatology 20081001

Title: Ocular pharmacokinetics of topically-applied ketoconazole solution containing hydroxypropyl beta-cyclodextrin to rabbits.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20081001

Title: Evidence for the mechanism of action of the antifungal phytolaccoside B isolated from Phytolacca tetramera Hauman.

Journal: Journal of natural products 20081001

Title: [Synergy between ajoene and ketoconazole in isolates of Microsporum canis. A preliminary study using fractional inhibitory concentration technique (FIC)].

Journal: Revista iberoamericana de micologia 20080930

Title: Screening of herbal constituents for aromatase inhibitory activity.

Journal: Bioorganic & medicinal chemistry 20080915

Title: Enamines as novel antibacterials and their structure-activity relationships.

Journal: European journal of medicinal chemistry 20080901

Title: Differential enzymatic reductions governing the differential hypoxia-selective cytotoxicities of phenazine 5,10-dioxides.

Journal: Chemical research in toxicology 20080901

Title: NO-donors. Part 17: Synthesis and antimicrobial activity of novel ketoconazole-NO-donor hybrid compounds.

Journal: Bioorganic & medicinal chemistry 20080901

Title: In vitro antifungal activity of polyfunctionalized 2-(hetero)arylquinolines prepared through imino Diels-Alder reactions.

Journal: Bioorganic & medicinal chemistry 20080901

Title: Steroidal saponins from the roots of Smilax aspera subsp. mauritanica.

Journal: Chemical & pharmaceutical bulletin 20080901

Title: Responses of the medaka HPG axis PCR array and reproduction to prochloraz and ketoconazole.

Journal: Environmental science & technology 20080901

Title: Comparison of the anti-inflammatory activities of imidazole antimycotics in relation to molecular structure.

Journal: Chemical biology & drug design 20080901

Title: Combined treatment with ketoconazole and cyproterone acetate in a boy with McCune-Albright syndrome and peripheral precocious puberty.

Journal: Journal of endocrinological investigation 20080901

Title: [A limited sampling strategy of phenotyping probe midazolam to predict inhibited activities of hepatic CYP3A in rats].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20080901

Title: Overcoming undesirable CYP1A2 inhibition of pyridylnaphthalene-type aldosterone synthase inhibitors: influence of heteroaryl derivatization on potency and selectivity.

Journal: Journal of medicinal chemistry 20080828

Title: Synthesis, biological evaluation, and molecular modeling of abiraterone analogues: novel CYP17 inhibitors for the treatment of prostate cancer.

Journal: Journal of medicinal chemistry 20080828

Title: Synthesis, biological evaluation, and molecular modeling studies of methylene imidazole substituted biaryls as inhibitors of human 17alpha-hydroxylase-17,20-lyase (CYP17)--part II: Core rigidification and influence of substituents at the methylene bridge.

Journal: Bioorganic & medicinal chemistry 20080815

Title: In situ dissolution testing using potentiometric sensors.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20080807

Title: Cushing's disease in dogs: cabergoline treatment.

Journal: Research in veterinary science 20080801

Title: Effects of ketoconazole and quinidine on pharmacokinetics of pactimibe and its plasma metabolite, R-125528, in humans.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080801

Title: Pharmacokinetics of darunavir/ritonavir and ketoconazole following co-administration in HIV-healthy volunteers.

Journal: British journal of clinical pharmacology 20080801

Title: Adverse effects of ketoconazole in dogs--a retrospective study.

Journal: Veterinary dermatology 20080801

Title: Dysgonic strain of Microsporum canis pseudomycetoma in a Domestic Long-hair cat.

Journal: Australian veterinary journal 20080801

Title: What's your assessment? Pityrosporum folliculitis.

Journal: Dermatology nursing 20080801

Title: [Effect of ketoconazole on the activity of CYP4503A4 and CYP450 1A2 of hepatic microsomes in healthy adults].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20080801

Title: Microsome biocolloids for rapid drug metabolism and inhibition assessment by LC-MS.

Journal: Drug metabolism letters 20080801

Title: A statistical methodology for drug-drug interaction surveillance.

Journal: Statistics in medicine 20080720

Title: Chemosensitization prevents tolerance of Aspergillus fumigatus to antimycotic drugs.

Journal: Biochemical and biophysical research communications 20080718

Title: New trypanocidal hybrid compounds from the association of hydrazone moieties and benzofuroxan heterocycle.

Journal: Bioorganic & medicinal chemistry 20080715

Title: Synthesis of novel ketoconazole derivatives as inhibitors of the human Pregnane X Receptor (PXR; NR1I2; also termed SXR, PAR).

Journal: Bioorganic & medicinal chemistry letters 20080715

Title: Expression of microsomal lanosterol 14alpha-demethylase (CYP51) in an engineered soluble monomeric form.

Journal: Biochemical and biophysical research communications 20080711

Title: 1-[(3-Aryloxy-3-aryl)propyl]-1H-imidazoles, new imidazoles with potent activity against Candida albicans and dermatophytes. Synthesis, structure-activity relationship, and molecular modeling studies.

Journal: Journal of medicinal chemistry 20080710

Title: A phase I study of docetaxel with ketoconazole modulation in patients with advanced cancers.

Journal: Cancer chemotherapy and pharmacology 20080701

Title: Synthesis and antimicrobial activities of 7-O-modified genistein derivatives.

Journal: European journal of medicinal chemistry 20080701

Title: Long-term treatment of familial male-limited precocious puberty (testotoxicosis) with cyproterone acetate or ketoconazole.

Journal: Clinical endocrinology 20080701

Title: Paecilomyces lilacinus olecranon bursitis in an immunocompromised host: case report and review.

Journal: Diagnostic microbiology and infectious disease 20080701

Title: Prediction of pharmacokinetic drug-drug interactions using human hepatocyte suspension in plasma and cytochrome P450 phenotypic data. II. In vitro-in vivo correlation with ketoconazole.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080701

Title: Perturbation of gene expression and steroidogenesis with in vitro exposure of fathead minnow ovaries to ketoconazole.

Journal: Marine environmental research 20080701

Title: Potent in vitro antifungal activities of naturally occurring acetylenic acids.

Journal: Antimicrobial agents and chemotherapy 20080701

Title: Evaluation and treatment of oral candidiasis in HIV/AIDS patients in Enugu, Nigeria.

Journal: Oral and maxillofacial surgery 20080701

Title: Synthesis, biochemical evaluation and rationalisation of the inhibitory activity of a range of phenyl alkyl imidazole-based compounds as potent inhibitors of the enzyme complex 17alpha-hydroxylase/17,20-lyase (P450(17alpha)).

Journal: The Journal of steroid biochemistry and molecular biology 20080701

Title: Validation and application of Caco-2 assays for the in vitro evaluation of development candidate drugs as substrates or inhibitors of P-glycoprotein to support regulatory submissions.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20080701

Title: [Ketoconazole and clindamycin efficacy vs oral clindamycin in premature membranes rupture prevention].

Journal: Ginecologia y obstetricia de Mexico 20080701

Title: Biotypes, genotypes and ketoconazole susceptibility of Candida albicans isolates from a group of Thai AIDS patients.

Journal: The new microbiologica 20080701

Title: Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).

Journal: Journal of medicinal chemistry 20080612

Title: Differential effects of ketoconazole on exposure to temsirolimus following intravenous infusion of temsirolimus.

Journal: British journal of cancer 20080603

Title: Malassezia folliculitis in China.

Journal: Mycopathologia 20080601

Title: In vitro antifungal susceptibility and molecular characterization of clinical isolates of Fusarium verticillioides (F. moniliforme) and Fusarium thapsinum.

Journal: Antimicrobial agents and chemotherapy 20080601

Title: Biweekly doxorubicin/ketoconazole as second-line treatment in docetaxel-resistant, hormone-refractory prostate cancer.

Journal: Urology 20080601

Title: Cutaneous hyalohyphomycosis caused by a Chrysosporium species related to Nannizziopsis vriesii in two green iguanas (Iguana iguana).

Journal: Medical mycology 20080601

Title: Synthesis and SAR studies of biaryloxy-substituted triazoles as antifungal agents.

Journal: Bioorganic & medicinal chemistry letters 20080601

Title: Safety profile and metabolic effects of 14 days of treatment with DIO-902: results of a phase IIa multicenter, randomized, double-blind, placebo-controlled, parallel-group trial in patients with type 2 diabetes mellitus.

Journal: Clinical therapeutics 20080601

Title: Application of micellar electrokinetic capillary chromatography for evaluation of inhibitory effects on cytochrome P450 reaction.

Journal: Journal of chromatography. A 20080502

Title: Synthesis and antimicrobial activity of novel sulfone-linked bis heterocycles.

Journal: European journal of medicinal chemistry 20080501

Title: An examination of the effect of intestinal first pass extraction on intestinal lymphatic transport of saquinavir in the rat.

Journal: Pharmaceutical research 20080501

Title: A stereospecific high-performance liquid chromatographic assay for the determination of ketoconazole enantiomers in rat plasma.

Journal: Biomedical chromatography : BMC 20080501

Title: Contribution of the N-glucuronidation pathway to the overall in vitro metabolic clearance of midazolam in humans.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080501

Title: Application of CYP3A4 in vitro data to predict clinical drug-drug interactions; predictions of compounds as objects of interaction.

Journal: British journal of clinical pharmacology 20080501

Title: In vitro inhibition of CYP3A4 metabolism and P-glycoprotein-mediated transport by trade herbal products.

Journal: Basic & clinical pharmacology & toxicology 20080501

Title: Oral ketoconazole for prevention of postoperative penile erection: a placebo controlled, randomized, double-blind trial.

Journal: The Journal of urology 20080501

Title: Identification of the human cytochrome P450 enzymes involved in the in vitro biotransformation of lynestrenol and norethindrone.

Journal: The Journal of steroid biochemistry and molecular biology 20080501

Title: Chiral separations in sub- and supercritical fluid chromatography.

Journal: Journal of separation science 20080501

Title: Identification of human cytochrome P450 enzymes involved in the metabolism of IN-1130, a novel activin receptor-like kinase-5 (ALK5) inhibitor.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20080501

Title: Effects of ketoconazole on the pharmacokinetics and pharmacodynamics of morphine in healthy Greyhounds.

Journal: American journal of veterinary research 20080501

Title: The effect of ketoconazole on the pharmacokinetics and pharmacodynamics of ixabepilone: a first in class epothilone B analogue in late-phase clinical development.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20080501

Title: Selected endocrine disrupting compounds (vinclozolin, flutamide, ketoconazole and dicofol): effects on survival, occurrence of males, growth, molting and reproduction of Daphnia magna.

Journal: Environmental science and pollution research international 20080501

Title: Ketoconazole: a review of a workhorse antifungal molecule with a focus on new foam and gel formulations.

Journal: Drugs of today (Barcelona, Spain : 1998) 20080501

Title: Significance of isolation and drug susceptibility testing of non-Candida albicans species causing oropharyngeal candidiasis in HIV patients.

Journal: The Southeast Asian journal of tropical medicine and public health 20080501

Title: [Effect of polyoxyl ether analogous surfactants on the activity of cytochromes P450 3A in rats in vivo].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20080501

Title: Design, synthesis, and biological evaluation of (hydroxyphenyl)naphthalene and -quinoline derivatives: potent and selective nonsteroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1) for the treatment of estrogen-dependent diseases.

Journal: Journal of medicinal chemistry 20080410

Title: New selective inhibitors of steroid 11beta-hydroxylation in the adrenal cortex. Synthesis and structure-activity relationship of potent etomidate analogues.

Journal: Journal of medicinal chemistry 20080410

Title: Spectroscopic and kinetic studies on the interaction of ketoconazole and povidone drugs with DDQ.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080401

Title: Ketoconazole-induced testicular damage in rats reduced by Gentiana extract.

Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20080401

Title: [Management of hypercortisolism].

Journal: La Revue de medecine interne 20080401

Title: Unexpected emergence of acute hepatic injury in patients treated repeatedly with ketoconazole.

Journal: Journal of clinical gastroenterology 20080401

Title: Effects of CYP3A4 inhibitors on the pharmacokinetics of maraviroc in healthy volunteers.

Journal: British journal of clinical pharmacology 20080401

Title: 'Anti-cortisolic' treatment of warts.

Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20080401

Title: Combinatorial anti-Trichophyton effects of Ligusticum chuanxiong essential oil components with antibiotics.

Journal: Archives of pharmacal research 20080401

Title: Phaeohyphomycosis caused by Ulocladium species in a cat.

Journal: The Veterinary record 20080329

Title: Predominant role of 25OHD in the negative regulation of PTH expression: clinical relevance for hypovitaminosis D.

Journal: Life sciences 20080326

Title: Synthesis, crystal structure and antimicrobial activity of deoxybenzoin derivatives from genistein.

Journal: European journal of medicinal chemistry 20080301

Title: Inhibition of luteinizing hormone secretion by testosterone in men requires aromatization for its pituitary but not its hypothalamic effects: evidence from the tandem study of normal and gonadotropin-releasing hormone-deficient men.

Journal: The Journal of clinical endocrinology and metabolism 20080301

Title: Mixed inhibition of P450 3A4 as a chemoprotective mechanism against aflatoxin B1-induced cytotoxicity with cis-terpenones.

Journal: Chemical research in toxicology 20080301

Title: A novel ketoconazole bioadhesive effervescent tablet for vaginal delivery: design, in vitro and 'in vivo' evaluation.

Journal: International journal of pharmaceutics 20080227

Title: Synthesis, biological evaluation and molecular modelling studies of methyleneimidazole substituted biaryls as inhibitors of human 17alpha-hydroxylase-17,20-lyase (CYP17). Part I: Heterocyclic modifications of the core structure.

Journal: Bioorganic & medicinal chemistry 20080215

Title: Ethnoveterinary study for antidermatophytic activity of Piper betle, Alpinia galanga and Allium ascalonicum extracts in vitro.

Journal: Research in veterinary science 20080201

Title: Pharmacological evaluation of C-3 modified Betulinic acid derivatives with potent anticancer activity.

Journal: Investigational new drugs 20080201

Title: Antifungal canthin-6-one series accumulate in lipid droplets and affect fatty acid metabolism in Saccharomyces cerevisiae.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20080201

Title: Coexistence of hERG current block and disruption of protein trafficking in ketoconazole-induced long QT syndrome.

Journal: British journal of pharmacology 20080201

Title: Ketoconazole and the modulation of multidrug resistance-mediated transport in Caco-2 and MDCKII-MDR1 drug transport models.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20080201

Title: Ketoconazole, an antifungal imidazole, increases the sensitivity of rainbow trout to 17alpha-ethynylestradiol exposure.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20080131

Title: Antifungal and cytotoxic activities of some N-substituted aniline derivatives bearing a hetaryl fragment.

Journal: Bioorganic & medicinal chemistry 20080115

Title: [Prophylactic antifungal treatment in critically ill patients. A survey of a Cochrane review].

Journal: Ugeskrift for laeger 20080107

Title: New triazole and triazolothiadiazine derivatives as possible antimicrobial agents.

Journal: European journal of medicinal chemistry 20080101

Title: Ritonavir 100 mg does not cause QTc prolongation in healthy subjects: a possible role as CYP3A inhibitor in thorough QTc studies.

Journal: Clinical pharmacology and therapeutics 20080101

Title: Biochemical and functional evidence for the control of pain mechanisms by dehydroepiandrosterone endogenously synthesized in the spinal cord.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080101

Title: Prediction of onset of crystallization from experimental relaxation times. II. Comparison between predicted and experimental onset times.

Journal: Journal of pharmaceutical sciences 20080101

Title: Pharmacokinetic interaction of ketoconazole and itraconazole with ciprofloxacin.

Journal: Biopharmaceutics & drug disposition 20080101

Title: Spectrofluorimetric study and detection of ketoconazole in the presence of beta-cyclodextrin.

Journal: Journal of fluorescence 20080101

Title: N-Phenyl and N-phenylalkyl-maleimides acting against Candida spp.: time-to-kill, stability, interaction with maleamic acids.

Journal: Bioorganic & medicinal chemistry 20080101

Title: Novel cholesterol biosynthesis inhibitors targeting human lanosterol 14alpha-demethylase (CYP51).

Journal: Bioorganic & medicinal chemistry 20080101

Title: The effects of CYP3A4 inhibition on erlotinib pharmacokinetics: computer-based simulation (SimCYP) predicts in vivo metabolic inhibition.

Journal: European journal of clinical pharmacology 20080101

Title: Synthesis, biological evaluation and molecular modelling studies of novel ACD- and ABD-ring steroidomimetics as inhibitors of CYP17.

Journal: Bioorganic & medicinal chemistry letters 20080101

Title: Activity of caspofungin and voriconazole against clinical isolates of Candida and other medically important yeasts by the CLSI M-44A disk diffusion method with Neo-Sensitabs tablets.

Journal: Chemotherapy 20080101

Title: Ketoconazole revisited: a preoperative or postoperative treatment in Cushing's disease.

Journal: European journal of endocrinology 20080101

Title: [Medical treatment for Cushing's syndrome].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20080101

Title: [Ectopic Cushing's syndrome caused by a functioning pancreatic neuroendocrine tumour in a patient with von Hippel-Lindau disease].

Journal: Revista espanola de medicina nuclear 20080101

Title: Novel concepts in androgen receptor blockade.

Journal: Cancer journal (Sudbury, Mass.) 20080101

Title: [Itraconazole treatment in the suspension of pathological fungal colonization of the airway in patients with pulmonary tuberculosis].

Journal: Problemy tuberkuleza i boleznei legkikh 20080101

Title: Dermatophyte susceptibilities to antifungal azole agents tested in vitro by broth macro and microdilution methods.

Journal: Revista do Instituto de Medicina Tropical de Sao Paulo 20080101

Title: The effectiveness of retinoic acid treatment in bladder cancer: impact on recurrence, survival and TGFalpha and VEGF as end-point biomarkers.

Journal: Cancer biology & therapy 20080101

Title: Prevention of bladder cancer recurrence by retinoic acid-ketoconazole: a promising strategy?

Journal: Cancer biology & therapy 20080101

Title: Effect of coadministered ketoconazole, a strong cytochrome P450 3A4 enzyme inhibitor, on the pharmacokinetics of ciclesonide and its active metabolite desisobutyryl-ciclesonide.

Journal: Clinical pharmacokinetics 20080101

Title: The metabolism of amiodarone by various CYP isoenzymes of human and rat, and the inhibitory influence of ketoconazole.

Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20080101

Title: CYP2D6 is primarily responsible for the metabolism of clomiphene.

Journal: Drug metabolism and pharmacokinetics 20080101

Title: [Susceptibility to antifungal agents among Cryptococcus neoformans varieties isolated from patients at a university hospital].

Journal: Revista da Sociedade Brasileira de Medicina Tropical 20080101

Title: Reduction of fluconazole susceptibility of Candida albicans in APECED patients due to long-term use of ketoconazole and miconazole.

Journal: Scandinavian journal of infectious diseases 20080101

Title: [Mycetoma].

Journal: Annales de dermatologie et de venereologie 20080101

Title: Protothecosis as a cause of chronic diarrhoea in a dog.

Journal: Polish journal of veterinary sciences 20080101

Title: A novel approach to the prediction of drug-drug interactions in humans based on the serum incubation method.

Journal: Drug metabolism and pharmacokinetics 20080101

Title: A Bayesian meta-analysis on published sample mean and variance pharmacokinetic data with application to drug-drug interaction prediction.

Journal: Journal of biopharmaceutical statistics 20080101

Title: Diffuse cutaneous leishmaniasis: co-infection with human immunodeficiency virus (HIV).

Journal: Indian journal of dermatology, venereology and leprology 20080101

Title: Tinea nigra by Hortaea werneckii, a report of 22 cases from Mexico.

Journal: Studies in mycology 20080101

Title: [Modern approach to treatment of trophic ulcers of legs with perifocal varicose eczema, associated with mycotic infection].

Journal: Khirurgiia 20080101

Title: Evaluation of the relationship between androgenetic alopecia and demodex infestation.

Journal: Indian journal of dermatology 20080101

Title: [Resistance to azolic compounds in clinical Trichophyton spp. strains].

Journal: Revista iberoamericana de micologia 20071231

Title: Composition, enantiomeric distribution, and antimicrobial activity of Tanacetum argenteum subsp. flabellifolium essential oil.

Journal: Journal of pharmaceutical and biomedical analysis 20071221

Title: Induction of the NAD(P)H:quinone oxidoreductase 1 by ketoconazole and itraconazole: a mechanism of cancer chemoprotection.

Journal: Cancer letters 20071208

Title: Interactions of azole antifungal agents with the human breast cancer resistance protein (BCRP).

Journal: Journal of pharmaceutical sciences 20071201

Title: Identification of human liver cytochrome P450 enzymes involved in biotransformation of vicriviroc, a CCR5 receptor antagonist.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20071201

Title: Cyclic conversion of the novel Src kinase inhibitor [7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amine (TG100435) and Its N-oxide metabolite by flavin-containing monoxygenases and cytochrome P450 reductase.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20071201

Title: Effect of hydration on the permeation of ketoconazole through human nail plate in vitro.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20071201

Title: Phase II study of ketoconazole plus granulocyte-macrophage colony-stimulating factor for prostate cancer: effect of extent of disease on outcome.

Journal: The Journal of urology 20071201

Title: Cytochrome P3A4 inhibitors and other constituents of Fibraurea tinctoria.

Journal: Journal of natural products 20071201

Title: Bioactive polychlorinated bibenzyls from the liverwort Riccardia polyclada.

Journal: Journal of natural products 20071201

Title: Pharmacokinetic interaction between ketoconazole and praziquantel in healthy volunteers.

Journal: Journal of clinical pharmacy and therapeutics 20071201

Title: Nodular pulmonary histoplasmosis in Cushing's disease: a case report and literature review.

Journal: Tennessee medicine : journal of the Tennessee Medical Association 20071201

Title: Quantitative correlations among CYP3A sensitive substrates and inhibitors: literature analysis.

Journal: Current drug metabolism 20071201

Title: In vivo anti-Chagas vinylthio-, vinylsulfinyl-, and vinylsulfonylbenzofuroxan derivatives.

Journal: Journal of medicinal chemistry 20071129

Title: Induction of drought stress tolerance by ketoconazole in Catharanthus roseus is mediated by enhanced antioxidant potentials and secondary metabolite accumulation.

Journal: Colloids and surfaces. B, Biointerfaces 20071115

Title: Rational prescription of drugs within similar therapeutic or structural class for gastrointestinal disease treatment: drug metabolism and its related interactions.

Journal: World journal of gastroenterology 20071114

Title: Adaptive therapy for androgen-independent prostate cancer: a randomized selection trial of four regimens.

Journal: Journal of the National Cancer Institute 20071107

Title: Pharmacokinetic modulation of oral etoposide by ketoconazole in patients with advanced cancer.

Journal: Cancer chemotherapy and pharmacology 20071101

Title: The cytochrome p450 inhibitor ketoconazole potentiates 5-hydroxytryptamine-induced contraction in rat aorta.

Journal: The Journal of pharmacology and experimental therapeutics 20071101

Title: Use of isolated hepatocyte preparations for cytochrome P450 inhibition studies: comparison with microsomes for Ki determination.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20071101

Title: Synthesis and antifungal activities of novel 2-aminotetralin derivatives.

Journal: Journal of medicinal chemistry 20071101

Title: Cytotoxic doses of ketoconazole affect expression of a subset of hepatic genes.

Journal: Journal of toxicology and environmental health. Part A 20071101

Title: [Malassezia folliculitis: characteristics and therapeutic response in 26 patients].

Journal: Annales de dermatologie et de venereologie 20071101

Title: Formulation compatibility of myristyl nicotinate with drugs used to treat dermatological conditions involving an impaired skin barrier.

Journal: Drug development and industrial pharmacy 20071101

Title: Pharmacological management of Cushing's syndrome: an update.

Journal: Arquivos brasileiros de endocrinologia e metabologia 20071101

Title: 33-Year-old man with cough, fever, and weight loss.

Journal: Mayo Clinic proceedings 20071001

Title: Metabolism of tacrolimus (FK506) and recent topics in clinical pharmacokinetics.

Journal: Drug metabolism and pharmacokinetics 20071001

Title: A novel foam formulation of ketoconazole 2% for the treatment of seborrheic dermatitis on multiple body regions.

Journal: Journal of drugs in dermatology : JDD 20071001

Title: Efficacy of low-dose ketoconazole in hormone refractory prostate cancer patients at the National Cancer Centre and The Cancer Institute, Singapore.

Journal: Annals of the Academy of Medicine, Singapore 20071001

Title: The role of ketoconazole in seborrheic dermatitis.

Journal: Cutis 20071001

Title: Effect of one month ketoconazole treatment on GH, cortisol and ACTH release after ghrelin, GHRP-6 and GHRH administration in patients with Cushing's disease.

Journal: Arquivos brasileiros de endocrinologia e metabologia 20071001

Title: [Metabolic products and pathway of neferine in rat liver].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20071001

Title: Drug-drug interaction prediction: a Bayesian meta-analysis approach.

Journal: Statistics in medicine 20070910

Title: Influence of ketoconazole on the fecal and urinary disposition of docetaxel.

Journal: Cancer chemotherapy and pharmacology 20070901

Title: Diagnosis and treatment of ocular coccidioidomycosis in a female captive chimpanzee (Pan troglodytes): a case study.

Journal: Annals of the New York Academy of Sciences 20070901

Title: Synthesis of novel triazole derivatives as inhibitors of cytochrome P450 14alpha-demethylase (CYP51).

Journal: European journal of medicinal chemistry 20070901

Title: Azole therapy of clinical and experimental coccidioidomycosis.

Journal: Annals of the New York Academy of Sciences 20070901

Title: Ciclosporin use in multi-drug therapy for meningoencephalomyelitis of unknown aetiology in dogs.

Journal: The Journal of small animal practice 20070901

Title: Effects of endocrine disrupting chemicals on expression of phospholipid hydroperoxide glutathione peroxidase mRNA in rat testes.

Journal: Journal of veterinary science 20070901

Title: Restoration of hormonal action and muscle protein.

Journal: Critical care medicine 20070901

Title: Effective treatment for dermatophytoses of the foot: effect on restoration of depressed cell-mediated immunity.

Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20070901

Title: Candida interface keratitis after deep anterior lamellar keratoplasty: clinical, microbiologic, histopathologic, and confocal microscopic reports.

Journal: Cornea 20070901

Title: Ketoconazole in the treatment of chronic idiopathic central serous chorioretinopathy.

Journal: Retina (Philadelphia, Pa.) 20070901

Title: Development of an in vivo rat screen model to predict pharmacokinetic interactions of CYP3A4 substrates.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20070901

Title: Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of bis[micro2-(benzimidazol-2-yl)-2-ethanethiolato-N,S,S-chloro-palladium(II)] dimer, [(micro2-CH2CH2NHNCC6H4)PdCl]2.C2H5OH complex.

Journal: European journal of medicinal chemistry 20070801

Title: Antiepileptic drugs affect neuronal androgen signaling via a cytochrome P450-dependent pathway.

Journal: The Journal of pharmacology and experimental therapeutics 20070801

Title: Transcription of key genes regulating gonadal steroidogenesis in control and ketoconazole- or vinclozolin-exposed fathead minnows.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20070801

Title: Combination of surgical avulsion and topical therapy for single nail onychomycosis: a randomized controlled trial.

Journal: The British journal of dermatology 20070801

Title: Activity of ketoconazole against Mycobacterium tuberculosis in vitro and in the mouse model.

Journal: Journal of medical microbiology 20070801

Title: Tinea capitis: no incision nor excision.

Journal: Journal of pediatric surgery 20070801

Title: Ketoconazole is inferior to ritonavir as an alternative booster for saquinavir in a once daily regimen in Thai HIV-1 infected patients.

Journal: AIDS (London, England) 20070731

Title: The prokinetic cinitapride has no clinically relevant pharmacokinetic interaction and effect on QT during coadministration with ketoconazole.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070701

Title: Eumycetoma presenting as a cerebellopontine angle mass lesion.

Journal: Clinical neurology and neurosurgery 20070701

Title: In vitro susceptibilities of 217 clinical isolates of zygomycetes to conventional and new antifungal agents.

Journal: Antimicrobial agents and chemotherapy 20070701

Title: Cytochrome P450-dependent metabolism of vitamin E isoforms is a critical determinant of their tissue concentrations in rats.

Journal: Lipids 20070701

Title: Identification and in vitro antifungal susceptibility testing of 200 clinical isolates of Candida spp. responsible for fingernail infections.

Journal: Mycopathologia 20070701

Title: Comparison between fluconazole and ketoconazole effectivity in the treatment of pityriasis versicolor.

Journal: Mycoses 20070701

Title: Oral paracoccidioidomycosis: a case without lung manifestations.

Journal: The journal of contemporary dental practice 20070701

Title: Melanin biosynthesis in Madurella mycetomatis and its effect on susceptibility to itraconazole and ketoconazole.

Journal: Microbes and infection 20070701

Title: Preparation, characterization, and scale-up of ketoconazole with enhanced dissolution and bioavailability.

Journal: Drug development and industrial pharmacy 20070701

Title: Tailored hormonal therapy in secretory adrenocortical cancer.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20070701

Title: [Enzyme kinetics of schizandrin metabolism and sex differences in rat liver microsomes].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20070701

Title: Optimisation of hydrocortisone production by Curvularia lunata.

Journal: Applied biochemistry and biotechnology 20070701

Title: Comparison of fast liquid chromatography/tandem mass spectrometric methods for simultaneous determination of cladribine and clofarabine in mouse plasma.

Journal: Journal of pharmaceutical and biomedical analysis 20070628

Title: Discovery of novel indazole-linked triazoles as antifungal agents.

Journal: Bioorganic & medicinal chemistry letters 20070615

Title: Possible inhibitory mechanism of Curcuma drugs on CYP3A4 in 1alpha,25 dihydroxyvitamin D3 treated Caco-2 cells.

Journal: International journal of pharmaceutics 20070607

Title: Hepatitis and rhabdomyolysis in a patient with hormone refractory prostate cancer on ketoconazole and concurrent lovastatin therapy.

Journal: Investigational new drugs 20070601

Title: Pharmacological prevention of the deleterious effects of cardiopulmonary bypass.

Journal: Asian cardiovascular & thoracic annals 20070601

Title: A new ketoconazole topical gel formulation in seborrhoeic dermatitis: an updated review of the mechanism.

Journal: Expert opinion on pharmacotherapy 20070601

Title: Ketoconazole in the fathead minnow (Pimephales promelas): reproductive toxicity and biological compensation.

Journal: Environmental toxicology and chemistry 20070601

Title: Life-threatening Pneumocystis jiroveci pneumonia following treatment of severe Cushing's syndrome.

Journal: The Netherlands journal of medicine 20070601

Title: Non-interventional management of obstructive acute renal-failure in hormone-naïve prostate cancer.

Journal: The Canadian journal of urology 20070601

Title: Electrochemical reduction of sterol-14alpha-demethylase from Mycobacterium tuberculosis (CYP51b1).

Journal: Biochemistry. Biokhimiia 20070601

Title: Ketoconazole gel 2% in the treatment of moderate to severe seborrheic dermatitis.

Journal: Cutis 20070601

Title: [Mediastinal lymph nodes during the course of a metastatic prostate cancer].

Journal: Actas urologicas espanolas 20070601

Title: Schistosoma haematobium and urinary tract pathogens co-infections in a rural community of Edo State, Nigeria.

Journal: The Journal of communicable diseases 20070601

Title: A lesson for everyone in drug-drug interactions.

Journal: International journal of cardiology 20070516

Title: MgMfs1, a major facilitator superfamily transporter from the fungal wheat pathogen Mycosphaerella graminicola, is a strong protectant against natural toxic compounds and fungicides.

Journal: Fungal genetics and biology : FG & B 20070501

Title: Induction of cytochrome P450 1A1 by ketoconazole and itraconazole but not fluconazole in murine and human hepatoma cell lines.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20070501

Title: Sequential metabolism is responsible for diltiazem-induced time-dependent loss of CYP3A.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070501

Title: Antifungal susceptibility testing of Trichophyton rubrum by E-test.

Journal: Archives of dermatological research 20070501

Title: Effect of efavirenz on the pharmacokinetics of ketoconazole in HIV-infected patients.

Journal: European journal of clinical pharmacology 20070501

Title: Cytochrome P450 3A inhibition by ketoconazole affects prasugrel and clopidogrel pharmacokinetics and pharmacodynamics differently.

Journal: Clinical pharmacology and therapeutics 20070501

Title: Estimation of intragastric solubility of drugs: in what medium?

Journal: Pharmaceutical research 20070501

Title: Electrochemical properties of cytochroms P450 using nanostructured electrodes: direct electron transfer and electro catalysis.

Journal: Journal of inorganic biochemistry 20070501

Title: Lecythophora hoffmannii isolated from a case of canine osteomyelitis in Japan.

Journal: Medical mycology 20070501

Title: Flutrimazole shampoo 1% versus ketoconazole shampoo 2% in the treatment of pityriasis versicolor. A randomised double-blind comparative trial.

Journal: Mycoses 20070501

Title: Plasma pharmacokinetics and CYP3A12-dependent metabolism of c-kit inhibitor imatinib in dogs.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20070501

Title: Interventions for treating oral candidiasis for patients with cancer receiving treatment.

Journal: The Cochrane database of systematic reviews 20070418

Title: Activated pregnenolone X-receptor is a target for ketoconazole and its analogs.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070415

Title: Antifungal treatment in sarcoidosis--a pilot intervention trial.

Journal: Respiratory medicine 20070401

Title: Characterization of hot-melt extruded drug delivery systems for onychomycosis.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20070401

Title: Synthesis and antimicrobial activities of Schiff bases derived from 5-chloro-salicylaldehyde.

Journal: European journal of medicinal chemistry 20070401

Title: Luteinizing hormone-induced caspase activation in rat preovulatory follicles is coupled to mitochondrial steroidogenesis.

Journal: Endocrinology 20070401

Title: Deacetylclivorine: a gender-selective metabolite of clivorine formed in female Sprague-Dawley rat liver microsomes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070401

Title: Second generation of 5-ethenylbenzofuroxan derivatives as inhibitors of Trypanosoma cruzi growth: synthesis, biological evaluation, and structure-activity relationships.

Journal: Bioorganic & medicinal chemistry 20070401

Title: Synthesis of DL-standishinal and its related compounds for the studies on structure-activity relationship of inhibitory activity against aromatase.

Journal: Bioorganic & medicinal chemistry 20070401

Title: In vitro activity of an ear rinse containing tromethamine, EDTA, benzyl alcohol and 0.1% ketoconazole on Malassezia organisms from dogs with otitis externa.

Journal: Veterinary dermatology 20070401

Title: Adrenal androgen levels as predictors of outcome in prostate cancer patients treated with ketoconazole plus antiandrogen withdrawal: results from a cancer and leukemia group B study.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070401

Title: Pharmacokinetic modelling of pentoxifylline and lisofylline after oral and intravenous administration in mice.

Journal: The Journal of pharmacy and pharmacology 20070401

Title: [Lithium gluconate 8% in the treatment of seborrheic dermatitis].

Journal: Annales de dermatologie et de venereologie 20070401

Title: Inhibitory or scavenging action of ketoconazole and ciclopiroxolamine against reactive oxygen species released by primed inflammatory cells.

Journal: The British journal of dermatology 20070401

Title: Effect of ion suppression on judgment of enzyme inhibition and avoidance of error by utilizing a stable isotope-labeled probe substrate: example of CYP3A4 inhibition with [13C4,15N] labeled midazolam as a substrate.

Journal: Drug metabolism and pharmacokinetics 20070401

Title: [Cushing syndrome].

Journal: Revue de l'infirmiere 20070401

Title: [Effectiveness of the treatment plan for androgenetic alopecia].

Journal: Georgian medical news 20070401

Title: Eumycetoma pedis due to Exophiala jeanselmei.

Journal: Indian journal of medical microbiology 20070401

Title: The development of a cocktail CYP2B6, CYP2C8, and CYP3A5 inhibition assay and a preliminary assessment of utility in a drug discovery setting.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070301

Title: Effect of oral ketoconazole on intestinal first-pass effect of midazolam and fexofenadine in cynomolgus monkeys.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070301

Title: Three-dimensional quantitative structure-activity relationship analysis of human CYP51 inhibitors.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070301

Title: Antifungal activities of azole agents against the Malassezia species.

Journal: International journal of antimicrobial agents 20070301

Title: Development of quantitative real-time PCR assays for fathead minnow (Pimephales promelas) gonadotropin beta subunit mRNAs to support endocrine disruptor research.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20070301

Title: Potential cancer chemopreventive in vitro activities of monomeric xanthone derivatives from the marine algicolous fungus Monodictys putredinis.

Journal: Journal of natural products 20070301

Title: Potentiating effects of nonactive/active vitamin D analogues and ketoconazole in parathyroid cells.

Journal: Clinical endocrinology 20070301

Title: Metronidazole 0.75% gel vs. ketoconazole 2% cream in the treatment of facial seborrheic dermatitis: a randomized, double-blind study.

Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20070301

Title: Clinical inquiries. What's the best treatment for cradle cap?

Journal: The Journal of family practice 20070301

Title: Antiplasmodial interactions between artemisinin and triclosan or ketoconazole combinations against blood stages of Plasmodium falciparum in vitro.

Journal: The American journal of tropical medicine and hygiene 20070301

Title: Report of an imported cutaneous disseminated case of paracoccidioidomycosis.

Journal: Revista iberoamericana de micologia 20070301

Title: Hyperadrenocorticism: treating dogs.

Journal: Compendium (Yardley, PA) 20070301

Title: CP-154,526, a CRF type-1 receptor antagonist, attenuates the cue-and methamphetamine-induced reinstatement of extinguished methamphetamine-seeking behavior in rats.

Journal: Psychopharmacology 20070201

Title: Evidence of Oatp and Mdr1 in cryopreserved rat hepatocytes.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20070201

Title: Synthesis, characterization and antimicrobial activity of Fe(II), Zn(II), Cd(II) and Hg(II) complexes with 2,6-bis(benzimidazol-2-yl) pyridine ligand.

Journal: European journal of medicinal chemistry 20070201

Title: Inhibition of CYP3A4 and CYP3A5 catalyzed metabolism of alprazolam and quinine by ketoconazole as racemate and four different enantiomers.

Journal: European journal of clinical pharmacology 20070201

Title: Transporter-mediated drug interactions: clinical implications and in vitro assessment.

Journal: Expert opinion on drug metabolism & toxicology 20070201

Title: [A text-book case of tropical facial elephantiasis].

Journal: Revue de stomatologie et de chirurgie maxillo-faciale 20070201

Title: Concentrations of mycophenolic acid and glucuronide metabolites under concomitant therapy with cyclosporine or tacrolimus.

Journal: Therapeutic drug monitoring 20070201

Title: [Oral isolates of Saccharomyces in patients with oral fungal infection and their susceptibility to antifungal drugs].

Journal: Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 20070201

Title: [Acanthamoeba keratitis: about the first two Tunisian cases].

Journal: Bulletin de la Societe de pathologie exotique (1990) 20070201

Title: [Cutaneous sporotricosis in a Malagasy patient].

Journal: Medecine tropicale : revue du Corps de sante colonial 20070201

Title: Determination of antifungal activity of polyenzyme preparation Candidaseb using in vitro methods.

Journal: Hindustan antibiotics bulletin 20070201

Title: Inhibition of drug metabolism by blocking the activation of nuclear receptors by ketoconazole.

Journal: Oncogene 20070111

Title: Effects of three cytochrome P450 inhibitors, ketoconazole, fluconazole, and paroxetine, on the pharmacokinetics of lasofoxifene.

Journal: British journal of clinical pharmacology 20070101

Title: Reversal of androgenetic alopecia by topical ketoconzole: relevance of anti-androgenic activity.

Journal: Journal of dermatological science 20070101

Title: A novel model for the prediction of drug-drug interactions in humans based on in vitro cytochrome p450 phenotypic data.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070101

Title: Synthesis and antifungal activity of (Z)-5-arylidenerhodanines.

Journal: Bioorganic & medicinal chemistry 20070101

Title: Design of endoperoxides with anti-Candida activity.

Journal: Bioorganic & medicinal chemistry 20070101

Title: Molecular evidence and functional expression of multidrug resistance associated protein (MRP) in rabbit corneal epithelial cells.

Journal: Experimental eye research 20070101

Title: Antimicrobial effectiveness of ketoconazole against metronidazole-resistant Helicobacter pylori isolates from Iranian dyspeptic patients.

Journal: The Journal of antimicrobial chemotherapy 20070101

Title: The stereoselective metabolism of halofantrine to desbutylhalofantrine in the rat: evidence of tissue-specific enantioselectivity in microsomal metabolism.

Journal: Chirality 20070101

Title: CYP3A4 mediated in vitro metabolism of vinflunine in human liver microsomes.

Journal: Acta pharmacologica Sinica 20070101

Title: 1H NMR monitoring of the canine metabolic profile after oral administration of xenobiotics using multivariate statistics.

Journal: Molecular pharmaceutics 20070101

Title: Value of colposcopy in the diagnosis of candidiasis in patients with vulvodynia.

Journal: The Journal of reproductive medicine 20070101

Title: Simultaneous determination of docetaxel and ketoconazole in rat plasma by liquid chromatography/electrospray ionization tandem mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20070101

Title: Comparison of different perrmeation enhancers on topical ketoconazole formulations.

Journal: Arzneimittel-Forschung 20070101

Title: Human intestinal P-glycoprotein activity estimated by the model substrate digoxin.

Journal: Scandinavian journal of clinical and laboratory investigation 20070101

Title: Ketoconazole therapy: an efficacious alternative to achieve eucortisolism in patients with Cushing's syndrome.

Journal: Medicina 20070101

Title: Antiviral and antimicrobial profiles of selected isoquinoline alkaloids from Fumaria and Corydalis species.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20070101

Title: Abdominal wall mycetoma presented as obstructed incisional hernia of cesarean section in eastern Sudan.

Journal: Infectious diseases in obstetrics and gynecology 20070101

Title: Significant prostate-specific antigen (PSA) response to low-dose ketoconazole in a patient with non-metastatic androgen-independent prostate cancer (AIPC) and a review of the literature.

Journal: American journal of therapeutics 20070101

Title: Pharmacokinetics of cinacalcet hydrochloride when administered with ketoconazole.

Journal: Clinical pharmacokinetics 20070101

Title: Clinical efficacies of shampoos containing ciclopirox olamine (1.5%) and ketoconazole (2.0%) in the treatment of seborrhoeic dermatitis.

Journal: The Journal of dermatological treatment 20070101

Title: Simultaneous ectopic adrenocorticotropic hormone syndrome and adrenal metastasis of a medullary thyroid carcinoma causing paraneoplastic Cushing's syndrome.

Journal: International seminars in surgical oncology : ISSO 20070101

Title: Extina foam (2%).

Journal: Skinmed 20070101

Title: Multiple oral dosing of ketoconazole increases dog exposure to ivermectin.

Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20070101

Title: Ketoconazole-evoked [Ca2+]i rises and non-Ca2+-triggered cell death in rabbit corneal epithelial cells (SIRC).

Journal: Journal of receptor and signal transduction research 20070101

Title: [Quo vadis, hypophysis? Some news and prospects].

Journal: Vnitrni lekarstvi 20070101

Title: Localized cutaneous leishmaniasis in South India: successful treatment with ketoconazole.

Journal: Indian journal of dermatology, venereology and leprology 20070101

Title: CYP3A4 and pregnane X receptor humanized mice.

Journal: Journal of biochemical and molecular toxicology 20070101

Title: [The 50th Anniversary Educational Symposium of the Japanese Society for Medical Mycology: Dermatomycoses caused by Malassezia].

Journal: Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology 20070101

Title: Effect of hypercortisolism control on high blood pressure in Cushing's syndrome.

Journal: Medicina 20070101

Title: Identification of CYP3A4 as the primary cytochrome P450 responsible for the metabolism of tandospirone by human liver microsomes.

Journal: European journal of drug metabolism and pharmacokinetics 20070101

Title: In vitro release--in vivo microbiological and toxicological studies on ketoconazole lipid granules.

Journal: Pharmaceutical development and technology 20070101

Title: Identification of CYP3A4 as the primary cytochrome P450 responsible for the metabolism of tandospirone by human liver microsomes.

Journal: European journal of drug metabolism and pharmacokinetics 20070101

Title: In vitro antifungal activity of 2-(4-substituted phenyl)-3(2H)-isothiazolones.

Journal: Folia microbiologica 20070101

Title: Pregnenolone and dexamethasone, modulators of cytochrome P450-3A, not increase but reduce urinary alpha-CEHC excretion in rats.

Journal: BioFactors (Oxford, England) 20070101

Title: Seborrhoeic dermatitis.

Journal: BMJ clinical evidence 20070101

Title: Treatment algorithm in hormone-resistant prostate cancer: Practical guidelines.

Journal: Indian journal of urology : IJU : journal of the Urological Society of India 20070101

Title: Repeated 28-day oral toxicity study of ketoconazole in rats based on the draft protocol for the 'Enhanced OECD Test Guideline No. 407' to detect endocrine effects.

Journal: Archives of toxicology 20061201

Title: The role of P-glycoprotein in the bioactivation of raloxifene.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20061201

Title: Drug-metabolizing enzyme inhibition by ketoconazole does not reduce interindividual variability of CYP3A activity as measured by oral midazolam.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20061201

Title: Antifungal susceptibilities of the species of the Pseudallescheria boydii complex.

Journal: Antimicrobial agents and chemotherapy 20061201

Title: Antifolates as antimycotics? Connection between the folic acid cycle and the ergosterol biosynthesis pathway in Candida albicans.

Journal: International journal of antimicrobial agents 20061201

Title: Cytochrome P450-dependent metabolism of midazolam in hepatic microsomes from chickens, turkeys, pheasant and bobwhite quail.

Journal: Journal of veterinary pharmacology and therapeutics 20061201

Title: White piedra in children.

Journal: Journal of the American Academy of Dermatology 20061201

Title: In vitro antifungal efficacy of ciclopirox olamine alone and associated with zinc pyrithione compared to ketoconazole against Malassezia globosa and Malassezia restricta reference strains.

Journal: Mycopathologia 20061201

Title: Mechanisms of venoocclusive disease resulting from the combination of cyclophosphamide and roxithromycin.

Journal: Therapeutic drug monitoring 20061201

Title: Preoperative immunosuppressive therapy and surgery as a treatment for anal furunculosis.

Journal: Veterinary surgery : VS 20061201

Title: Bioactive oligostilbenoids from the stem bark of Hopea exalata.

Journal: Journal of natural products 20061201

Title: Evaluation of the effects of hydrophilic organic solvents on CYP3A-mediated drug-drug interaction in vitro.

Journal: Human & experimental toxicology 20061201

Title: [Study on metabolism of tetramethylpyrazine in system of rat liver microsomes].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20061201

Title: [Canine lymphadenitis caused by Cryptococcus neoformans. First case in Chile].

Journal: Revista iberoamericana de micologia 20061201

Title: Common pharmacophores for uncharged human ether-a-go-go-related gene (hERG) blockers.

Journal: Journal of medicinal chemistry 20061116

Title: Human adrenocarcinoma (H295R) cells for rapid in vitro determination of effects on steroidogenesis: hormone production.

Journal: Toxicology and applied pharmacology 20061115

Title: The H295R system for evaluation of endocrine-disrupting effects.

Journal: Ecotoxicology and environmental safety 20061101

Title: Effectiveness and tolerability of a standardized extract from Ageratina pichinchensis on patients with tinea pedis: an explorative pilot study controlled with ketoconazole.

Journal: Planta medica 20061101

Title: In vitro methods for antifungal susceptibility testing of Trichophyton spp.

Journal: Mycological research 20061101

Title: Otomycosis: clinical features and treatment implications.

Journal: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20061101

Title: OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice.

Journal: PLoS medicine 20061101

Title: Inhibition of the enzymatic activity of heme oxygenases by azole-based antifungal drugs.

Journal: The Journal of pharmacology and experimental therapeutics 20061001

Title: Characterization of the rhesus monkey CYP3A64 enzyme: species comparisons of CYP3A substrate specificity and kinetics using baculovirus-expressed recombinant enzymes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20061001

Title: Metabolism of endosulfan-alpha by human liver microsomes and its utility as a simultaneous in vitro probe for CYP2B6 and CYP3A4.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20061001

Title: Influence of tartaric acid on the bioadhesion and mechanical properties of hot-melt extruded hydroxypropyl cellulose films for the human nail.

Journal: Drug development and industrial pharmacy 20061001

Title: Decision support tool to individualize cyclosporine dose in stable, long-term heart transplant recipients receiving metabolic inhibitors: overcoming limitations of cyclosporine C2 monitoring.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20061001

Title: In-vitro susceptibility testing by agar dilution method to determine the minimum inhibitory concentrations of amphotericin B, fluconazole and ketoconazole against ocular fungal isolates.

Journal: Indian journal of medical microbiology 20061001

Title: A fission yeast-based test system for the determination of IC50 values of anti-prostate tumor drugs acting on CYP21.

Journal: Journal of enzyme inhibition and medicinal chemistry 20061001

Title: Evidence for cytochrome P450 3A expression and catalytic activity in rat blood lymphocytes.

Journal: Life sciences 20060927

Title: Synthesis, biochemical evaluation and rationalisation of the inhibitory activity of a range of 4-substituted phenyl alkyl imidazole-based inhibitors of the enzyme complex 17alpha-hydroxylase/17,20-lyase (P450(17alpha)).

Journal: Bioorganic & medicinal chemistry letters 20060915

Title: Retinoic acid as a novel medical therapy for Cushing's disease in dogs.

Journal: Endocrinology 20060901

Title: Response to low-dose ketoconazole and subsequent dose escalation to high-dose ketoconazole in patients with androgen-independent prostate cancer.

Journal: Cancer 20060901

Title: Disopyramide: although potentially life-threatening in the setting of long QT, could it be life-saving in short QT syndrome?

Journal: Journal of molecular and cellular cardiology 20060901

Title: Metabolism and metabolic inhibition of gambogic acid in rat liver microsomes.

Journal: Acta pharmacologica Sinica 20060901

Title: Metabolic activation of pradefovir by CYP3A4 and its potential as an inhibitor or inducer.

Journal: Antimicrobial agents and chemotherapy 20060901

Title: RAT CYP3A and CYP2B1/2 were not associated with nevirapine-induced hepatotoxicity.

Journal: Methods and findings in experimental and clinical pharmacology 20060901

Title: Intervention at the level of the neuroendocrine-immune axis and postoperative pneumonia rate in long-term alcoholics.

Journal: American journal of respiratory and critical care medicine 20060815

Title: Suppressive effects of antimycotics on tumor necrosis factor-alpha-induced CCL27, CCL2, and CCL5 production in human keratinocytes.

Journal: Biochemical pharmacology 20060814

Title: The use of a fluorescence-based oxygen uptake assay in the analysis of cytotoxicity.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20060801

Title: Novel ketoconazole analogues based on the replacement of 2,4-dichlorophenyl group with 1,4-benzothiazine moiety: design, synthesis, and microbiological evaluation.

Journal: Bioorganic & medicinal chemistry 20060801

Title: Inhibition of UDP-glucuronosyltransferase 2b7-catalyzed morphine glucuronidation by ketoconazole: dual mechanisms involving a novel noncompetitive mode.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060801

Title: Activating mutations in the luteinizing hormone receptor gene: a human model of non-follicle-stimulating hormone-dependent inhibin production and germ cell maturation.

Journal: The Journal of clinical endocrinology and metabolism 20060801

Title: Synthesis and biochemical evaluation of a range of potent benzyl imidazole-based compounds as potential inhibitors of the enzyme complex 17alpha-hydroxylase/17,20-lyase (P450(17alpha)).

Journal: Bioorganic & medicinal chemistry letters 20060801

Title: Use of omeprazole sulfone in a single plasma sample as a probe for CYP3A4.

Journal: European journal of clinical pharmacology 20060801

Title: Secondary hormonal manipulations in prostate cancer.

Journal: Hematology/oncology clinics of North America 20060801

Title: Transporter-mediated intestinal absorption of fexofenadine in rats.

Journal: Drug metabolism and pharmacokinetics 20060801

Title: Cushing's paraneoplastic syndrome as first manifestation of an adenocarcinoma of unknown origin.

Journal: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20060801

Title: Optimization and validation of a high-performance liquid chromatographic method with UV detection for the determination of ketoconazole in canine plasma.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060724

Title: Enhancement of DMNQ-induced hepatocyte toxicity by cytochrome P450 inhibition.

Journal: Toxicology and applied pharmacology 20060715

Title: Clinical results of topical fluconazole for the treatment of filamentous fungal keratitis.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20060701

Title: Stereoselective metabolism of endosulfan by human liver microsomes and human cytochrome P450 isoforms.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060701

Title: Quinacrine is mainly metabolized to mono-desethyl quinacrine by CYP3A4/5 and its brain accumulation is limited by P-glycoprotein.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060701

Title: Expression, purification, and characterization of mouse CYP2d22.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060701

Title: Ketoconazole and miconazole are antagonists of the human glucocorticoid receptor: consequences on the expression and function of the constitutive androstane receptor and the pregnane X receptor.

Journal: Molecular pharmacology 20060701

Title: Stochastic prediction of CYP3A-mediated inhibition of midazolam clearance by ketoconazole.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060701

Title: Influence of high-dose ketoconazole on the pharmacokinetics of docetaxel.

Journal: Cancer biology & therapy 20060701

Title: In vitro susceptibilities of Malaysian clinical isolates of Cryptococcus neoformans var. grubii and Cryptococcus gattii to five antifungal drugs.

Journal: Mycoses 20060701

Title: Predictive power of an in vitro system to assess drug interactions of an antimuscarinic medication: a comparison of in vitro and in vivo drug-drug interaction studies of trospium chloride with digoxin.

Journal: Journal of clinical pharmacology 20060701

Title: Pharmacokinetic effect of ketoconazole on solifenacin in healthy volunteers.

Journal: Basic & clinical pharmacology & toxicology 20060701

Title: Phytochemistry and antifungal properties of the newly discovered tree Pleodendron costaricense.

Journal: Journal of natural products 20060701

Title: Chronic mucocutaneous candidiasis associated with malignant thymoma and systemic lupus erythematosus with hypergammaglobulinemia: a case report and literature review.

Journal: Cutis 20060701

Title: Interaction between ketoconazole and domperidone and the risk of QT prolongation--important safety information.

Journal: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20060701

Title: Pharmacokinetic interaction between ketoconazole and SPP301 in healthy volunteers.

Journal: International journal of clinical pharmacology and therapeutics 20060701

Title: Biotransformation of fluticasone: in vitro characterization.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060601

Title: Comparison of mouse and rat cytochrome P450-mediated metabolism in liver and intestine.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060601

Title: Phase II study of mitoxantrone and ketoconazole for hormone-refractory prostate cancer.

Journal: Cancer 20060601

Title: In vitro antifungal activities of Allium cepa, Allium sativum and ketoconazole against some pathogenic yeasts and dermatophytes.

Journal: Fitoterapia 20060601

Title: Man versus machine: is there an optimal method for QT measurements in thorough QT studies?

Journal: Journal of clinical pharmacology 20060601

Title: Cytoskeleton reassembly in cardiomyocytes infected by Trypanosoma cruzi is triggered by treatment with ergosterol biosynthesis inhibitors.

Journal: International journal of antimicrobial agents 20060601

Title: Canine intestinal contents vs. simulated media for the assessment of solubility of two weak bases in the human small intestinal contents.

Journal: Pharmaceutical research 20060601

Title: Antifungal effects of the volatile oils from Allium plants against Trichophyton species and synergism of the oils with ketoconazole.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20060601

Title: Ketoconazole as a secondary hormonal intervention in advanced prostate cancer.

Journal: Clinical journal of oncology nursing 20060601

Title: Polymorphic behaviour of Compritol888 ATO as bulk lipid and as SLN and NLC.

Journal: Journal of microencapsulation 20060601

Title: Fungal toenail infections.

Journal: Clinical evidence 20060601

Title: Surface plasmon resonance analysis of antifungal azoles binding to CYP3A4 with kinetic resolution of multiple binding orientations.

Journal: Biochemistry 20060523

Title: Identification and quantitation of cis-ketoconazole impurity by capillary zone electrophoresis-mass spectrometry.

Journal: Journal of chromatography. A 20060505

Title: alpha(2)-Adrenergic receptors activate MAPK and Akt through a pathway involving arachidonic acid metabolism by cytochrome P450-dependent epoxygenase, matrix metalloproteinase activation and subtype-specific transactivation of EGFR.

Journal: Cellular signalling 20060501

Title: Lack of effect of ketoconazole-mediated CYP3A inhibition on sorafenib clinical pharmacokinetics.

Journal: Cancer chemotherapy and pharmacology 20060501

Title: Metabolism and effect of para-toluene-sulfonamide on rat liver microsomal cytochrome P450 from in vivo and in vitro studies.

Journal: Acta pharmacologica Sinica 20060501

Title: The use of SLN and NLC as topical particulate carriers for imidazole antifungal agents.

Journal: Die Pharmazie 20060501

Title: [Skin infection with Fusarium in an immunocompetent patient].

Journal: Actas dermo-sifiliograficas 20060501

Title: [Three cases of cutaneous blastomycosis].

Journal: Medecine et maladies infectieuses 20060501

Title: Structure-based optimization of azole antifungal agents by CoMFA, CoMSIA, and molecular docking.

Journal: Journal of medicinal chemistry 20060420

Title: Drugs for treating paracoccidioidomycosis.

Journal: The Cochrane database of systematic reviews 20060419

Title: Synthesis and evaluation of heteroaryl-substituted dihydronaphthalenes and indenes: potent and selective inhibitors of aldosterone synthase (CYP11B2) for the treatment of congestive heart failure and myocardial fibrosis.

Journal: Journal of medicinal chemistry 20060406

Title: Inhibition of the HERG K+ channel by the antifungal drug ketoconazole depends on channel gating and involves the S6 residue F656.

Journal: FEBS letters 20060403

Title: Development, validation and utility of an in vitro technique for assessment of potential clinical drug-drug interactions involving P-glycoprotein.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20060401

Title: In vitro and in vivo inhibitory effect of stiripentol on clobazam metabolism.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060401

Title: Interactions of two major metabolites of prasugrel, a thienopyridine antiplatelet agent, with the cytochromes P450.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060401

Title: Identification of human liver cytochrome P450 enzymes responsible for the metabolism of lonafarnib (Sarasar).

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060401

Title: Antifungal agents for preventing fungal infections in non-neutropenic critically ill and surgical patients: systematic review and meta-analysis of randomized clinical trials.

Journal: The Journal of antimicrobial chemotherapy 20060401

Title: Formation of 4'-carboxyl acid metabolite of imrecoxib by rat liver microsomes.

Journal: Acta pharmacologica Sinica 20060401

Title: Long term control of hypercortisolism with fluconazole: case report and in vitro studies.

Journal: European journal of endocrinology 20060401

Title: In vitro efficacy of a buffered chelating solution as an antimicrobial potentiator for antifungal drugs against fungal pathogens obtained from horses with mycotic keratitis.

Journal: American journal of veterinary research 20060401

Title: Ketoconazole renders poor CYP3A phenotype status with midazolam as probe drug.

Journal: Therapeutic drug monitoring 20060401

Title: Acanthamoeba keratitis in a 5-year-old boy without a history of contact lens usage.

Journal: Cornea 20060401

Title: Aureobasidium pullulans keratitis.

Journal: Clinical & experimental ophthalmology 20060401

Title: [The effect of propyl gallate on the activity of various antifungal drugs against filamentous fungi in vitro].

Journal: [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20060401

Title: The vitamin D prodrugs 1alpha(OH)D2, 1alpha(OH)D3 and BCI-210 suppress PTH secretion by bovine parathyroid cells.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060301

Title: Coxiella burnetii inhabits a cholesterol-rich vacuole and influences cellular cholesterol metabolism.

Journal: Cellular microbiology 20060301

Title: Inhibition of Vitamin D3 metabolism enhances VDR signalling in androgen-independent prostate cancer cells.

Journal: The Journal of steroid biochemistry and molecular biology 20060301

Title: [Penicilliosis in Laos].

Journal: Presse medicale (Paris, France : 1983) 20060301

Title: Novel endoperoxides: synthesis and activity against Candida species.

Journal: Bioorganic & medicinal chemistry letters 20060215

Title: Partial structures of ketoconazole as modulators of the large conductance calcium-activated potassium channel (BK(Ca)).

Journal: Bioorganic & medicinal chemistry letters 20060215

Title: Griseofulvin and ketoconazole solubilization by bile salts studied using fluorescence spectroscopy.

Journal: Colloids and surfaces. B, Biointerfaces 20060201

Title: Clinical evolution of paracoccidioidomycosis in 38 children and teenagers.

Journal: Mycopathologia 20060201

Title: Use of capecitabine after renal allograft transplantation in dog erythrocyte antigen-matched dogs.

Journal: Veterinary surgery : VS 20060201

Title: CYP3A4 activity in four different animal species liver microsomes using 7-benzyloxyquinoline and HPLC/spectrofluorometric determination.

Journal: Journal of pharmaceutical and biomedical analysis 20060123

Title: Development of a fluorescence-based assay for screening of modulators of human organic anion transporter 1B3 (OATP1B3).

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20060101

Title: Dysmorphogenic effects of some fungicides derived from the imidazole on rat embryos cultured in vitro.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20060101

Title: Determination of the enzyme(s) involved in the metabolism of amiodarone in liver and intestine of rat: the contribution of cytochrome P450 3A isoforms.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060101

Title: Intestinal and hepatic CYP3A4 catalyze hydroxylation of 1alpha,25-dihydroxyvitamin D(3): implications for drug-induced osteomalacia.

Journal: Molecular pharmacology 20060101

Title: An unusual presentation of malassezia dermatosis.

Journal: Dermatology (Basel, Switzerland) 20060101

Title: Hyperkeratotic head and neck Malassezia dermatosis.

Journal: Dermatology (Basel, Switzerland) 20060101

Title: Impact of the cyclosporine-ketoconazole interaction in children with steroid-dependent idiopathic nephrotic syndrome.

Journal: European journal of clinical pharmacology 20060101

Title: Effects of cytochrome P450 3A modulators ketoconazole and carbamazepine on quetiapine pharmacokinetics.

Journal: British journal of clinical pharmacology 20060101

Title: Bioavailability of two oral formulations of loratadine 20 mg with concomitant ketoconazole: an open-label, randomized, two-period crossover comparison in healthy Mexican adult volunteers.

Journal: Clinical therapeutics 20060101

Title: Effect of drug utilization reviews on the quality of in-hospital prescribing: a quasi-experimental study.

Journal: BMC health services research 20060101

Title: Recurrent vulvovaginal candidiasis.

Journal: Missouri medicine 20060101

Title: Carney complex (CNC).

Journal: Orphanet journal of rare diseases 20060101

Title: Malassezia and seborrheic dermatitis: etiology and treatment.

Journal: Journal of cosmetic science 20060101

Title: Ketoconazole-tacrolimus coadministration in kidney transplant recipients: two-year results of a prospective randomized study.

Journal: American journal of nephrology 20060101

Title: In vitro studies on quetiapine metabolism using the substrate depletion approach with focus on drug-drug interactions.

Journal: Drug metabolism and drug interactions 20060101

Title: Efficacy and safety of a new once-daily topical ketoconazole 2% gel in the treatment of seborrheic dermatitis: a phase III trial.

Journal: Journal of drugs in dermatology : JDD 20060101

Title: In vitro activity of R126638 and ketoconazole against Malassezia species.

Journal: Acta dermato-venereologica 20060101

Title: Clinical features and diagnosis of 42 travellers with cutaneous leishmaniasis.

Journal: Travel medicine and infectious disease 20060101

Title: [Effect of steroid biosynthesis modificators on the progesterone biotransformation by a recombinant yeasts expressing cytochrome P450c17].

Journal: Biomeditsinskaia khimiia 20060101

Title: Xolegel (ketoconazole, 2%).

Journal: Skinmed 20060101

Title: [Drug-related problems in a patient with Cushing's disease].

Journal: Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20060101

Title: Mycetoma : a review.

Journal: American journal of clinical dermatology 20060101

Title: Clinical efficacy of a new ciclopiroxolamine/zinc pyrithione shampoo in scalp seborrheic dermatitis treatment.

Journal: European journal of dermatology : EJD 20060101

Title: Effect of ketoconazole and rifampicin on the pharmacokinetics of ranitidine in healthy human volunteers: a possible role of P-glycoprotein.

Journal: Drug metabolism and drug interactions 20060101

Title: Effect of ketoconazole on the pharmacokinetics of ornidazole--a possible role of p-glycoprotein and CYP3A.

Journal: Drug metabolism and drug interactions 20060101

Title: [Laboratory evolutive aspects of children under paracoccidioidomycosis treatment].

Journal: Revista da Sociedade Brasileira de Medicina Tropical 20060101

Title: Co-administration of ketoconazole and tacrolimus therapy: a transplanted rat model.

Journal: International urology and nephrology 20060101

Title: [Relative bioavailability and bioequivalence of the antimycotics ketoconazole and fluconazole].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20060101

Title: In vitro susceptibility of oral Candida to seven antifungal agents.

Journal: Oral microbiology and immunology 20051201

Title: Significant differences in the disposition of cyclic prodrugs of opioid peptides in rats and guinea pigs following IV administration.

Journal: Journal of pharmaceutical sciences 20051201

Title: Bioactive small molecules reveal antagonism between the integrated stress response and sterol-regulated gene expression.

Journal: Cell metabolism 20051201

Title: Evaluation and treatment of Cushing's syndrome.

Journal: The American journal of medicine 20051201

Title: A comparison of hair quality and cosmetic acceptance following the use of two anti-dandruff shampoos.

Journal: The journal of investigative dermatology. Symposium proceedings 20051201

Title: Effects of beta-thujaplicin on anti-Malassezia pachydermatis remedy for canine otitis externa.

Journal: The Journal of veterinary medical science 20051201

Title: Ketoconazole induced torsades de pointes without concomitant use of QT interval-prolonging drug.

Journal: Journal of cardiovascular electrophysiology 20051201

Title: Fungal nail infections.

Journal: Clinical evidence 20051201

Title: Candidiasis (vulvovaginal).

Journal: Clinical evidence 20051201

Title: Novel tetralone-derived retinoic acid metabolism blocking agents: synthesis and in vitro evaluation with liver microsomal and MCF-7 CYP26A1 cell assays.

Journal: Journal of medicinal chemistry 20051117

Title: Characterization of rat small intestinal and colon precision-cut slices as an in vitro system for drug metabolism and induction studies.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20051101

Title: Uncommon clinical presentations of cutaneous leishmaniasis in Sudan.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20051101

Title: Upregulation of sterol C14-demethylase expression in Trypanosoma cruzi treated with sterol biosynthesis inhibitors.

Journal: Molecular and biochemical parasitology 20051101

Title: Effect of azole antifungals ketoconazole and fluconazole on the pharmacokinetics of dexloxiglumide.

Journal: British journal of clinical pharmacology 20051101

Title: The effect of calcium chelating or binding agents on Candida albicans.

Journal: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20051101

Title: Clinical status of agents being developed for leishmaniasis.

Journal: Expert opinion on investigational drugs 20051101

Title: Extraction, hemisynthesis, and synthesis of canthin-6-one analogues. Evaluation of their antifungal activities.

Journal: Journal of natural products 20051101

Title: An overview of antifungal drugs and their use for treatment of deep and superficial mycoses in animals.

Journal: Clinical techniques in small animal practice 20051101

Title: [Metabolic kinetics of MN9202 in Beagle dog liver microsomes].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20051101

Title: Increase of the LC-MS/MS sensitivity and detection limits using on-line sample preparation with large volume plasma injection.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20051025

Title: Characterization of human cytochrome P450 isoenzymes involved in the metabolism of vinorelbine.

Journal: Fundamental & clinical pharmacology 20051001

Title: [Drug-drug interaction of antifungal drugs].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20051001

Title: The effects of inhibiting cytochrome P450 3A, p-glycoprotein, and gastric acid secretion on the oral bioavailability of methadone in dogs.

Journal: Journal of veterinary pharmacology and therapeutics 20051001

Title: Enantiomeric separation of ketoconazole and terconazole antifungals by electrokinetic chromatography: Rapid quantitative analysis of ketoconazole in pharmaceutical formulations.

Journal: Electrophoresis 20051001

Title: The role of ketoconazole in the prevention of ovarian hyperstimulation syndrome in patients with polycystic ovary syndrome during assisted reproductive technology cycles.

Journal: Saudi medical journal 20051001

Title: Effects of ketoconazole on glucuronidation by UDP-glucuronosyltransferase enzymes.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20050915

Title: [Determination of antidangdruff agent salicylic acid, zinc pyrithione, octopirox, climbazole and ketoconazole in shampoo by high performance liquid chromatography].

Journal: Wei sheng yan jiu = Journal of hygiene research 20050901

Title: Increased expression and hotspot mutations of the multidrug efflux transporter, CDR1 in azole-resistant Candida albicans isolates from vaginitis patients.

Journal: FEMS microbiology letters 20050815

Title: Metabolism of the alpha,beta-unsaturated ketones, chalcone and trans-4-phenyl-3-buten-2-one, by rat liver microsomes and estrogenic activity of the metabolites.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20050801

Title: The advantages of the Ussing chamber in drug absorption studies.

Journal: Journal of biomolecular screening 20050801

Title: 2-O-(2-hydroxybutyl)-beta-cyclodextrin as a chiral selector for the capillary electrophoretic separation of chiral drugs.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20050801

Title: DNA fingerprinting pattern and susceptibility to antifungal drugs in Cryptococcus neoformans variety grubii isolates from Barcelona city and rural environmental samples.

Journal: Mycopathologia 20050801

Title: Identification of OATP1B3 as a high-affinity hepatocellular transporter of paclitaxel.

Journal: Cancer biology & therapy 20050801

Title: Ketobemidone is a substrate for cytochrome P4502C9 and 3A4, but not for P-glycoprotein.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20050801

Title: SLN and NLC for topical delivery of ketoconazole.

Journal: Journal of microencapsulation 20050801

Title: [3H]linopirdine binding to rat brain membranes is not relevant for M-channel interaction.

Journal: European journal of pharmacology 20050725

Title: Development and application of a new on-line SPE system combined with LC-MS/MS detection for high throughput direct analysis of pharmaceutical compounds in plasma.

Journal: Journal of chromatography. A 20050708

Title: Effect of several compounds on biliary excretion of paclitaxel and its metabolites in guinea-pigs.

Journal: Anti-cancer drugs 20050701

Title: Dimemorfan N-demethylation by mouse liver microsomal cytochrome P450 enzymes.

Journal: Life sciences 20050701

Title: Alanine scanning of transmembrane helix 11 of Cdr1p ABC antifungal efflux pump of Candida albicans: identification of amino acid residues critical for drug efflux.

Journal: The Journal of antimicrobial chemotherapy 20050701

Title: A novel foam vehicle for delivery of topical corticosteroids.

Journal: Journal of the American Academy of Dermatology 20050701

Title: Rate-limiting biotransformation of triamterene is mediated by CYP1A2.

Journal: International journal of clinical pharmacology and therapeutics 20050701

Title: Fusarium solani breast abscess.

Journal: Indian journal of medical microbiology 20050701

Title: [In vitro activity of ketoconazole, itraconazole and terbinafine against Malassezia strains isolated from neonates].

Journal: Mikrobiyoloji bulteni 20050701

Title: Characterization of testosterone 11 beta-hydroxylation catalyzed by human liver microsomal cytochromes P450.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20050601

Title: Long-term outcome for men with androgen independent prostate cancer treated with ketoconazole and hydrocortisone.

Journal: The Journal of urology 20050601

Title: Ketoconazole increases plasma concentrations of antimalarial mefloquine in healthy human volunteers.

Journal: Journal of clinical pharmacy and therapeutics 20050601

Title: The effect of ketoconazole on the pharmacokinetics of a selective alpha 1A-adrenoceptor antagonist.

Journal: Journal of clinical pharmacology 20050601

Title: Genome-wide expression profiling of the response to azole, polyene, echinocandin, and pyrimidine antifungal agents in Candida albicans.

Journal: Antimicrobial agents and chemotherapy 20050601

Title: Comparison of the clinical efficacy of oral terbinafine and ketoconazole combined with cephalexin in the treatment of Malassezia dermatitis in dogs--a pilot study.

Journal: Veterinary dermatology 20050601

Title: [Abdominal zygomycosis in a bitch due to Absidia corymbifera].

Journal: Revista iberoamericana de micologia 20050601

Title: Effect of 2-(4-aminophenylmethyl)-6-hydroxy-3, 4-dihydronaphthalen-1(2H)-one on all-trans and 13-cis-retinoic acid levels in plasma quantified by high perfomance liquid chromatography coupled to tandem mass spectrometry.

Journal: Journal of enzyme inhibition and medicinal chemistry 20050601

Title: [Allergic fungal sinusitis and allergic broncho-pulmonary aspergillosis: a fortuitous association or a nosological rhino-bronchial entity?].

Journal: Revue des maladies respiratoires 20050601

Title: [Comparison of efficacy of combination of ketokonazol 400 mg + clindamycin 100 mg with ketokonazol 800 mg + clindamycin 100 mg in the treatment of vaginitis due to Candida and bacterial vaginosis].

Journal: Ginecologia y obstetricia de Mexico 20050601

Title: Lack of cataleptogenic potentiation with non-imidazole H3 receptor antagonists reveals potential drug-drug interactions between imidazole-based H3 receptor antagonists and antipsychotic drugs.

Journal: Brain research 20050531

Title: Selective inhibition of dog hepatic CYP2B11 and CYP3A12.

Journal: The Journal of pharmacology and experimental therapeutics 20050501

Title: Intestinal metabolism of PAH: in vitro demonstration and study of its impact on PAH transfer through the intestinal epithelium.

Journal: Environmental research 20050501

Title: Anti-proliferative synergy of lysophospholipid analogues and ketoconazole against Trypanosoma cruzi (Kinetoplastida: Trypanosomatidae): cellular and ultrastructural analysis.

Journal: The Journal of antimicrobial chemotherapy 20050501

Title: Blood concentrations of everolimus are markedly increased by ketoconazole.

Journal: Journal of clinical pharmacology 20050501

Title: Comparison of in vitro activities of antifungal drugs and ethanolic extract of propolis against Trichophyton rubrum and T. mentagrophytes by using a microdilution assay.

Journal: Mycoses 20050501

Title: Separation study of cadmium as CdI4(2-) through a bulk liquid membrane containing ketoconazole and oleic acid.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20050501

Title: Effect of solubilizing and microemulsifying excipients in polyethylene glycol 6000 solid dispersion on enhanced dissolution and bioavailability of ketoconazole.

Journal: Archives of pharmacal research 20050501

Title: Mefloquine resistance reversal action of ketoconazole - a cytochrome P450 inhibitor, against mefloquine-resistant malaria.

Journal: Parasitology 20050501

Title: Slime production and proteinase activity of Candida species isolated from blood samples and the comparison of these activities with minimum inhibitory concentration values of antifungal agents.

Journal: Memorias do Instituto Oswaldo Cruz 20050501

Title: Cloning and heterologous expression of the NADPH cytochrome P450 oxidoreductase genes from an industrial dicarboxylic acid-producing Candida tropicalis.

Journal: Yeast (Chichester, England) 20050430

Title: Novel C-17-heteroaryl steroidal CYP17 inhibitors/antiandrogens: synthesis, in vitro biological activity, pharmacokinetics, and antitumor activity in the LAPC4 human prostate cancer xenograft model.

Journal: Journal of medicinal chemistry 20050421

Title: Enhancement of nifedipine-induced gingival overgrowth by concomitant ketoconazole in rats.

Journal: Pharmacology 20050401

Title: Xenobiotics and the glucocorticoid receptor: additive antagonistic effects on tyrosine aminotransferase activity in rat hepatoma cells.

Journal: Basic & clinical pharmacology & toxicology 20050401

Title: Studies to investigate the pharmacokinetic interactions between ranolazine and ketoconazole, diltiazem, or simvastatin during combined administration in healthy subjects.

Journal: Journal of clinical pharmacology 20050401

Title: Transient band-like keratopathy after treatment for seborrheic dermatitis.

Journal: Cornea 20050401

Title: A study of the in vitro interaction between lidocaine and premedications using human liver microsomes.

Journal: Journal of clinical pharmacy and therapeutics 20050401

Title: Topical application of ketoconazole stimulates hair growth in C3H/HeN mice.

Journal: The Journal of dermatology 20050401

Title: Hepatotoxicity associated with cyclosporine monitoring using C2 recommendations in adults renal recipients receiving ketoconazole.

Journal: Transplantation proceedings 20050401

Title: Assessment of the hepatic and intestinal first-pass metabolism of midazolam in a CYP3A drug-drug interaction model rats.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20050401

Title: Oxidative stress mediates drug-induced hepatotoxicity in rats: a possible role of DNA fragmentation.

Journal: Toxicology 20050330

Title: Synthesis and evaluation of imidazolylmethylenetetrahydronaphthalenes and imidazolylmethyleneindanes: potent inhibitors of aldosterone synthase.

Journal: Journal of medicinal chemistry 20050324

Title: Microbiological assay of ketoconazole in shampoo.

Journal: International journal of pharmaceutics 20050323

Title: Synthesis and evaluation of (pyridylmethylene)tetrahydronaphthalenes/-indanes and structurally modified derivatives: potent and selective inhibitors of aldosterone synthase.

Journal: Journal of medicinal chemistry 20050310

Title: Metabolism of alfentanil by cytochrome p4503a (cyp3a) enzymes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20050301

Title: Experimentally induced androgen depletion accentuates ethnicity-related contrasts in luteinizing hormone secretion in asian and caucasian men.

Journal: The Journal of clinical endocrinology and metabolism 20050301

Title: Characterization of human cytochrome P450 enzymes involved in the in vitro metabolism of perospirone.

Journal: Biopharmaceutics & drug disposition 20050301

Title: Refractory anaphylactic shock associated with ketoconazole treatment.

Journal: The Annals of pharmacotherapy 20050301

Title: A randomized, phase II trial of ketoconazole plus alendronate versus ketoconazole alone in patients with androgen independent prostate cancer and bone metastases.

Journal: The Journal of urology 20050301

Title: Population-based case-control study of oral ketoconazole treatment for birth outcomes.

Journal: Congenital anomalies 20050301

Title: Pityriasis versicolor alba.

Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20050301

Title: Co-administration of ketoconazole with H1-antagonists ebastine and loratadine in healthy subjects: pharmacokinetic and pharmacodynamic effects.

Journal: British journal of clinical pharmacology 20050301

Title: Seborrheic dermatitis. The link between facial rash and neurologic disease.

Journal: Postgraduate medicine 20050301

Title: Effect of ketoconazole on the pharmacokinetics and safety of telithromycin and clarithromycin in older subjects with renal impairment.

Journal: International journal of clinical pharmacology and therapeutics 20050301

Title: Pharmacological management of paracoccidioidomycosis.

Journal: Expert opinion on pharmacotherapy 20050301

Title: Molecular design of two sterol 14alpha-demethylase homology models and their interactions with the azole antifungals ketoconazole and bifonazole.

Journal: Journal of computer-aided molecular design 20050301

Title: A simultaneous assessment of CYP3A4 metabolism and induction in the DPX-2 cell line.

Journal: The AAPS journal 20050301

Title: CYP3A4 is a vitamin D-24- and 25-hydroxylase: analysis of structure function by site-directed mutagenesis.

Journal: The Journal of clinical endocrinology and metabolism 20050201

Title: In vivo effects of cyclosporin A and ketoconazole on the pharmacokinetics of representative substrates for P-glycoprotein and cytochrome P450 (CYP) 3A in rats.

Journal: Biological & pharmaceutical bulletin 20050201

Title: [Metabolism of bicyclol in rat and human liver microsomes in vitro].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20050201

Title: Role of ketoconazole in renal transplant recipients.

Journal: Transplantation 20050127

Title: Antifungal and insect antifeedant 2-phenylethanol esters from the liverwort Balantiopsis cancellata from Chile.

Journal: Journal of agricultural and food chemistry 20050126

Title: Age and testosterone feedback jointly control the dose-dependent actions of gonadotropin-releasing hormone in healthy men.

Journal: The Journal of clinical endocrinology and metabolism 20050101

Title: Adult height after ketoconazole treatment in patients with familial male-limited precocious puberty.

Journal: The Journal of clinical endocrinology and metabolism 20050101

Title: A phase I study of estramustine, weekly docetaxel, and carboplatin chemotherapy in patients with hormone-refractory prostate cancer.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20050101

Title: Potent CYP3A4 inhibitory constituents of Piper cubeba.

Journal: Journal of natural products 20050101

Title: Corneofungimetry bioassay on Malassezia spp. under ketoconazole and desonide influences.

Journal: Skin pharmacology and physiology 20050101

Title: Determination of the absolute configuration and solution conformation of the antifungal agents ketoconazole, itraconazole, and miconazole with vibrational circular dichroism.

Journal: Chirality 20050101

Title: Co-administration of cyclosporine and ketoconazole in children with minimal change nephrotic syndrome.

Journal: Nephron. Clinical practice 20050101

Title: [Entomophthoramycosis (zygomycosis) caused by Conidiobolus coronatus in Mato Grosso (Brazil): case report].

Journal: Revista da Sociedade Brasileira de Medicina Tropical 20050101

Title: Phaeohyphomycosis in Korea.

Journal: Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology 20050101

Title: Clinical treatment of corneal infection due to Fonsecaea pedrosoi--case report.

Journal: Arquivos brasileiros de oftalmologia 20050101

Title: Estimation of potency of HERG channel blockers: impact of voltage protocol and temperature.

Journal: Journal of pharmacological and toxicological methods 20050101

Title: Antifungal susceptibilities of dermatophytic agents isolated from clinical specimens.

Journal: European journal of dermatology : EJD 20050101

Title: Case report of subcutaneous entomophthoromycosis with retroperitoneal invasion.

Journal: Revista da Sociedade Brasileira de Medicina Tropical 20050101

Title: Efficient short-term control of hypercortisolaemia by low-dose etomidate in severe paediatric Cushing's disease.

Journal: Hormone research 20050101

Title: Trichophyton tonsurans associated tinea corporis infection with the development of Majocchi's granuloma in a renal transplant patient.

Journal: Journal of drugs in dermatology : JDD 20050101

Title: Co-administration of ketoconazole and tacrolimus therapy: a transplanted rat model.

Journal: International urology and nephrology 20050101

Title: An evaluation of high-doses ketoconazole with hydrocortisone substitution in hormone-refractory prostate cancer.

Journal: Acta chirurgica Iugoslavica 20050101

Title: [Effect of tofisopam on CYP3A4 enzyme activity on human recombinant 3A4 supersome].

Journal: Acta pharmaceutica Hungarica 20050101

Title: [Successful treatment of a case of extense verrucous chromoblastomychosis with surgical exeresis associated with the use of ketoconazole].

Journal: Revista cubana de medicina tropical 20050101

Title: Novel retinoic acid metabolism blocking agents endowed with multiple biological activities are efficient growth inhibitors of human breast and prostate cancer cells in vitro and a human breast tumor xenograft in nude mice.

Journal: Journal of medicinal chemistry 20041230

Title: Potent, selective and low-calcemic inhibitors of CYP24 hydroxylase: 24-sulfoximine analogues of the hormone 1alpha,25-dihydroxyvitamin D(3).

Journal: Journal of medicinal chemistry 20041230

Title: In vitro metabolism of carbofuran by human, mouse, and rat cytochrome P450 and interactions with chlorpyrifos, testosterone, and estradiol.

Journal: Chemico-biological interactions 20041207

Title: Identification and characterization of potent CYP3A4 inhibitors in Schisandra fruit extract.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20041201

Title: Influence of ketoconazole on azimilide pharmacokinetics in healthy subjects.

Journal: British journal of clinical pharmacology 20041201

Title: Synergistic interaction between ketoconazole and several antidepressant drugs with allopregnanolone treatments in ovariectomized Wistar rats forced to swim.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20041201

Title: In vitro antifungal activity of sertaconazole compared with nine other drugs against 250 clinical isolates of dermatophytes and Scopulariopsis brevicaulis.

Journal: Chemotherapy 20041201

Title: Combination therapy of once-weekly fluconazole (100, 150, or 300 mg) with topical application of ketoconazole cream in the treatment of onychomycosis.

Journal: Japanese journal of infectious diseases 20041201

Title: Clinicopathologic features of an unusual outbreak of cryptococcosis in dogs, cats, ferrets, and a bird: 38 cases (January to July 2003).

Journal: Journal of the American Veterinary Medical Association 20041201

Title: Effect of various cytochrome P450 3A and P-glycoprotein modulators on the biliary clearance of bromosulphaphthalein in male wistar rats.

Journal: Die Pharmazie 20041201

Title: Synthesis and antileishmanial activity of 3-imidazolylalkylindoles. Part I.

Journal: Journal of enzyme inhibition and medicinal chemistry 20041201

Title: Gamma-tocotrienol metabolism and antiproliferative effect in prostate cancer cells.

Journal: Annals of the New York Academy of Sciences 20041201

Title: Seborrhoeic dermatitis.

Journal: Clinical evidence 20041201

Title: Synthesis and CYP24 inhibitory activity of 2-substituted-3,4-dihydro-2H-naphthalen-1-one (tetralone) derivatives.

Journal: Bioorganic & medicinal chemistry letters 20041115

Title: Tumor apoptosis induced by ruthenium(II)-ketoconazole is enhanced in nonsusceptible carcinoma by monoclonal antibody to EGF receptor.

Journal: International journal of cancer 20041110

Title: A phase I trial of pharmacokinetic modulation of carboxyamidotriazole (CAI) with ketoconazole in patients with advanced cancer.

Journal: Cancer chemotherapy and pharmacology 20041101

Title: Effects of acute and chronic ketoconazole administration on hypothalamo--pituitary--adrenal axis activity and brain corticotropin-releasing hormone.

Journal: Psychoneuroendocrinology 20041101

Title: (2S,3R)-2-aminododecan-3-ol, a new antifungal agent from the ascidian Clavelina oblonga.

Journal: Journal of natural products 20041101

Title: Vulvovaginal candidiasis in children and adolescents with type 1 diabetes mellitus.

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20041101

Title: [Treatment for seborrheic dermatitis].

Journal: Annales de dermatologie et de venereologie 20041101

Title: Pharmacokinetic interaction between ketoconazole and imatinib mesylate (Glivec) in healthy subjects.

Journal: Cancer chemotherapy and pharmacology 20041001

Title: Stress-restress evokes sustained iNOS activity and altered GABA levels and NMDA receptors in rat hippocampus.

Journal: Psychopharmacology 20041001

Title: Effect of ketoconazole on the pharmacokinetics of rosiglitazone in healthy subjects.

Journal: British journal of clinical pharmacology 20041001

Title: The systemic treatment of onychomycosis.

Journal: Clinics in podiatric medicine and surgery 20041001

Title: Pathogenesis of allergic bronchopulmonary aspergillosis and an evidence-based review of azoles in treatment.

Journal: Respiratory medicine 20041001

Title: Multiple oral dosing of ketoconazole influences pharmacokinetics of quinidine after intravenous and oral administration in beagle dogs.

Journal: Journal of veterinary pharmacology and therapeutics 20041001

Title: Comparative evaluation of Sensititre YeastOne vs. the NCCLS M27A protocol and E-test for antifungal susceptibility testing of yeasts.

Journal: Mycoses 20041001

Title: Anti-Candida effects of estragole in combination with ketoconazole or amphotericin B.

Journal: Phytotherapy research : PTR 20041001

Title: Influence of human nail etching for the assessment of topical onychomycosis therapies.

Journal: International journal of pharmaceutics 20040910

Title: Concomitant administration of cyclosporine and ketoconazole in idiopathic nephrotic syndrome.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20040901

Title: Co-administration of cyclosporine and ketoconazole in idiopathic childhood nephrosis.

Journal: Pediatric nephrology (Berlin, Germany) 20040901

Title: CYP2B6, CYP3A4, and CYP2C19 are responsible for the in vitro N-demethylation of meperidine in human liver microsomes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20040901

Title: Identification of an N-methyl-4-phenylpyridinium-like metabolite of the antidiarrheal agent loperamide in human liver microsomes: underlying reason(s) for the lack of neurotoxicity despite the bioactivation event.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20040901

Title: In vitro metabolism of MK-0767 [(+/-)-5-[(2,4-dioxothiazolidin-5-yl)methyl]-2-methoxy-N-[[(4-trifluoromethyl) phenyl]methyl]benzamide], a peroxisome proliferator-activated receptor alpha/gamma agonist. I. Role of cytochrome P450, methyltransferases, flavin monooxygenases, and esterases.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20040901

Title: Effect of cytochrome P450 inhibitors (diethyl dithiocarbamate, ketoconazole and grapefruit juice) on the pharmacokinetics of all-trans-retinoic acid.

Journal: Farmaco (Societa chimica italiana : 1989) 20040901

Title: Comparative study of 2% ketoconazole cream and 1% hydrocortisone cream in the treatment of infantile seborrheic dermatitis.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20040901

Title: Use of oral ketoconazole to prevent postoperative erections following penile surgery.

Journal: International journal of impotence research 20040801

Title: Interaction of triazolam and ketoconazole in P-glycoprotein-deficient mice.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20040801

Title: Concurrent Fusarium chlamydosporum and Microsphaeropsis arundinis infections in a cat.

Journal: Journal of feline medicine and surgery 20040801

Title: Ketoconazole, a cytochrome P450 3A4 inhibitor, markedly increases concentrations of levo-acetyl-alpha-methadol in opioid-naive individuals.

Journal: Clinical pharmacology and therapeutics 20040801

Title: Paranasal sinus aspergillosis: its categorization to develop a treatment protocol.

Journal: Mycoses 20040801

Title: Invasion of epithelial mammalian cells by Paracoccidioides brasiliensis leads to cytoskeletal rearrangement and apoptosis of the host cell.

Journal: Microbes and infection 20040801

Title: Specific interactions of steroids, arylhydrocarbons and flavonoids with progesterone receptors from the cytosol of the fungus Rhizopus nigricans.

Journal: The Journal of steroid biochemistry and molecular biology 20040801

Title: Imidazole analogues of fluoxetine, a novel class of anti-Candida agents.

Journal: Journal of medicinal chemistry 20040729

Title: Computer-assisted design of selective imidazole inhibitors for cytochrome p450 enzymes.

Journal: Journal of medicinal chemistry 20040701

Title: Bioequivalence evaluation of two brands of ketoconazole tablets (Onofin-K and Nizoral) in a healthy female Mexican population.

Journal: Biopharmaceutics & drug disposition 20040701

Title: Sesquiterpenes and flavonol glycosides from Zingiber aromaticum and their CYP3A4 and CYP2D6 inhibitory activities.

Journal: Journal of natural products 20040701

Title: Ketoconazole, an antifungal agent, protects against adiposity induced by a cafeteria diet.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20040701

Title: Improved outcome of zygomycosis in patients with hematological diseases?

Journal: Leukemia & lymphoma 20040701

Title: Prescribing practices for seborrheic dermatitis vary with the physician's specialty: implications for clinical practice.

Journal: The Journal of dermatological treatment 20040701

Title: Antifungal chalcones and new caffeic acid esters from Zuccagnia punctata acting against soybean infecting fungi.

Journal: Journal of agricultural and food chemistry 20040602

Title: Co-administration of ketoconazole to tacrolimus-treated kidney transplant recipients: a prospective randomized study.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20040601

Title: Oral administration of a low dose of midazolam (75 microg) as an in vivo probe for CYP3A activity.

Journal: European journal of clinical pharmacology 20040601

Title: Susceptibility of sequential Fonsecaea pedrosoi isolates from chromoblastomycosis patients to antifungal agents.

Journal: Mycoses 20040601

Title: Lipid raft polarization contributes to hyphal growth in Candida albicans.

Journal: Eukaryotic cell 20040601

Title: Chromoblastomycosis caused by Rhinocladiella aquaspersa.

Journal: Medical mycology 20040601

Title: Antifungal susceptibility of 50 Candida isolates from invasive mycoses in Chile.

Journal: Medical mycology 20040601

Title: Human cytochrome P450: metabolism of testosterone by CYP3A4 and inhibition by ketoconazole.

Journal: Current protocols in toxicology 20040601

Title: A prospective, randomized study of coadministration of ketoconazole and cyclosporine a in kidney transplant recipients: ten-year follow-up.

Journal: Transplantation 20040515

Title: An evaluation of intermediate-dose ketoconazole in hormone refractory prostate cancer.

Journal: European urology 20040501

Title: The use of a cyclosporin-ketoconazole combination: making renal transplantation affordable in developing countries.

Journal: European journal of clinical pharmacology 20040501

Title: Effect of cytochrome P450 3A4 inhibition on the pharmacokinetics of docetaxel.

Journal: Clinical pharmacology and therapeutics 20040501

Title: Comparison of capillary zone electrophoresis and high performance liquid chromatography methods for quantitative determination of ketoconazole in drug formulations.

Journal: Farmaco (Societa chimica italiana : 1989) 20040501

Title: Pharmacologic management of pattern hair loss.

Journal: Facial plastic surgery clinics of North America 20040501

Title: Efficacy of combined cyclosporine A and ketoconazole treatment of anal furunculosis.

Journal: The Journal of small animal practice 20040501

Title: Multicentric lymphoma in a dog after cyclosporine therapy.

Journal: The Journal of small animal practice 20040501

Title: Effects of the antifungal imidazole ketoconazole on CYP1A and CYP3A in rainbow trout and killifish.

Journal: Environmental toxicology and chemistry 20040501

Title: Model for the drug-drug interaction responsible for CYP3A enzyme inhibition. I: evaluation of cynomolgus monkeys as surrogates for humans.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20040501

Title: Model for the drug-drug interaction responsible for CYP3A enzyme inhibition. II: establishment and evaluation of dexamethasone-pretreated female rats.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20040501

Title: Identification and relative contributions of human cytochrome P450 isoforms involved in the metabolism of glibenclamide and lansoprazole: evaluation of an approach based on the in vitro substrate disappearance rate.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20040501

Title: Role of CYP3A enzymes in the biotransformation of triazolam in rat liver.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20040501

Title: Cyclosporine and low-dose ketoconazole in renal transplant recipients: a single-center experience.

Journal: Transplantation 20040415

Title: In vitro metabolism of fipronil by human and rat cytochrome P450 and its interactions with testosterone and diazepam.

Journal: Chemico-biological interactions 20040415

Title: The use of the novel substrate-heme complex approach in the derivation of a representation of the active site of the enzyme complex 17alpha-hydroxylase and 17,20-lyase.

Journal: Biochemical and biophysical research communications 20040409

Title: Comparison of prediction methods for in vivo clearance of (S,S)-3-[3-(methylsulfonyl)phenyl]-1-propylpiperidine hydrochloride, a dopamine D2 receptor antagonist, in humans.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20040401

Title: Quantitative contribution of CYP2D6 and CYP3A to oxycodone metabolism in human liver and intestinal microsomes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20040401

Title: Prevalence of Candida dubliniensis among germ tube-positive yeasts recovered from the respiratory specimens in HIV-negative patients.

Journal: Mycoses 20040401

Title: Prostate cancer metastasis to supraclavicular lymph node.

Journal: Clinical advances in hematology & oncology : H&O 20040401

Title: Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies.

Journal: Biochemical and biophysical research communications 20040319

Title: Antiandrogen withdrawal alone or in combination with ketoconazole in androgen-independent prostate cancer patients: a phase III trial (CALGB 9583).

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040315

Title: History of the development of azole derivatives.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20040301

Title: [Ketoconazole in the prevention of acute delirium episodes].

Journal: Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) 20040301

Title: Solubilizing poorly soluble antimycotic agents by emulsification via a solvent-free process.

Journal: AAPS PharmSciTech 20040301

Title: Chronic mucocutaneous candidiasis: a case report.

Journal: Journal of the Indian Society of Pedodontics and Preventive Dentistry 20040301

Title: Role of multiple drug resistance protein 1 in neutral but not acidic glycosphingolipid biosynthesis.

Journal: The Journal of biological chemistry 20040227

Title: Sirolimus and ketoconazole co-prescription in renal transplant recipients.

Journal: Transplantation 20040215

Title: Synthesis and antifungal activities of phenylenedithioureas.

Journal: Bioorganic & medicinal chemistry letters 20040209

Title: Enantioselectivity of inhibition of cytochrome P450 3A4 (CYP3A4) by ketoconazole: Testosterone and methadone as substrates.

Journal: Chirality 20040201

Title: Comparative efficacy of topical therapy with a slow-release mucoadhesive buccal tablet containing miconazole nitrate versus systemic therapy with ketoconazole in HIV-positive patients with oropharyngeal candidiasis.

Journal: Journal of acquired immune deficiency syndromes (1999) 20040201

Title: Development of an in vivo preclinical screen model to estimate absorption and first-pass hepatic extraction of xenobiotics. II. Use of ketoconazole to identify P-glycoprotein/CYP3A-limited bioavailability in the monkey.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20040201

Title: Efficacy of a new ketoconazole bioadhesive vaginal tablet on Candida albicans.

Journal: Farmaco (Societa chimica italiana : 1989) 20040201

Title: [Modern antimycotics. What the treating physician needs to know].

Journal: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20040201

Title: Role of phenobarbital-inducible cytochrome P450s as a source of active oxygen species in DNA-oxidation.

Journal: Cancer letters 20040120

Title: Synthesis of galactopyranosyl amino alcohols as a new class of antitubercular and antifungal agents.

Journal: Bioorganic & medicinal chemistry letters 20040119

Title: Highly selective inhibition of human CYP3Aa in vitro by azamulin and evidence that inhibition is irreversible.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20040101

Title: Ketocazole as an adjunct to finasteride in the treatment of androgenetic alopecia in men.

Journal: Medical hypotheses 20040101

Title: High-throughput screening for the assessment of time-dependent inhibitions of new drug candidates on recombinant CYP2D6 and CYP3A4 using a single concentration method.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20040101

Title: Interventions for treating oral candidiasis for patients with cancer receiving treatment.

Journal: The Cochrane database of systematic reviews 20040101

Title: Drug-drug interactions evaluated by a highly active reconstituted native human cytochrome P4503A4 and human NADPH-cytochrome P450 reductase system.

Journal: Arzneimittel-Forschung 20040101

Title: The role of cytochrome-P450 inhibitors in the prevention of hepatotoxicity after paracetamol overdose in rats.

Journal: Human & experimental toxicology 20040101

Title: Oral paracoccidioidomycosis or squamous cell carcinoma?

Journal: General dentistry 20040101

Title: Antimycotics: why are they effective in the treatment of seborrheic dermatitis?

Journal: Dermatology (Basel, Switzerland) 20040101

Title: Effect of concomitant administration of cyclosporine and ketoconazole in children with focal segmental glomerulosclerosis.

Journal: American journal of nephrology 20040101

Title: In vitro fungitoxic activity of Larrea divaricata cav. extracts.

Journal: Letters in applied microbiology 20040101

Title: Azoles for allergic bronchopulmonary aspergillosis associated with asthma.

Journal: The Cochrane database of systematic reviews 20040101

Title: In vitro antifungal susceptibility of Candida spp. isolates from patients with chronic periodontitis and from control patients.

Journal: Brazilian oral research 20040101

Title: In vitro susceptibility of Candida species isolated from cancer patients to some antifungal agents.

Journal: Drug metabolism and drug interactions 20040101

Title: [Determination of biological activity of hydrogel preparations based on ketoconazole and clotrimazole].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20040101

Title: Resistance reversal action of ketoconazole against mefloquine resistance of Plasmodium yoelii nigeriensis.

Journal: Experimental parasitology 20040101

Title: Determination of pharmaceutical compounds in skin by imaging matrix-assisted laser desorption/ionisation mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20040101

Title: Antifungal effects of herbal essential oils alone and in combination with ketoconazole against Trichophyton spp.

Journal: Journal of applied microbiology 20040101

Title: Etest for assessing the susceptibility of filamentous fungi.

Journal: Acta microbiologica et immunologica Hungarica 20040101

Title: Metastatic hepatic carcinoid associated with ectopic ACTH syndrome, resistant to octreotide and ketoconazole therapy.

Journal: Annals of Saudi medicine 20040101

Title: In vitro activities of transition metal derivatives of ketoconazole and clotrimazole against a wild type strain of Saccharomyces cerevisiae in absence or presence of human neutrophils.

Journal: Arzneimittel-Forschung 20040101

Title: Management of androgen-independent prostate cancer.

Journal: Cancer control : journal of the Moffitt Cancer Center 20040101

Title: Spontaneous remission of Cushing's disease after disappearance of a microadenoma attached to the pituitary stalk.

Journal: Pituitary 20040101

Title: [Prophylaxis of fungal infection in patients with hematologic neoplasms and severe neutropenia after high-dose chemotherapy].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20040101

Title: Cushing's disease and pregnancy.

Journal: Pituitary 20040101

Title: [Current possibilities of using antimyocotic drugs in the treatment of various skin disorders].

Journal: Wiadomosci parazytologiczne 20040101

Title: The influence of ketoconazole on the activity of asparagine protease produced by Candida strains.

Journal: Research communications in molecular pathology and pharmacology 20040101

Title: Microbial transformation of (-)-carvone.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20040101

Title: Phase 3 randomized trial evaluating second-line hormonal therapy versus docetaxel-estramustine combination chemotherapy on progression-free survival in asymptomatic patients with a rising prostate-specific antigen level after hormonal therapy for prostate cancer: an Eastern Cooperative Oncology Group (E1899), Intergroup/Clinical Trials Support Unit study.

Journal: Urology 20031229

Title: QT and RR intervals in conscious and anesthetized guinea pigs with highly varying RR intervals and given QTc-lengthening test articles.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20031201

Title: Experimental evaluation of antifungal and antiseptic agents against Rhodotorula spp.

Journal: Mycoses 20031201

Title: Trypanocidal constituents in plants 2.xanthones from the stem bark of Garcinia subelliptica.

Journal: Biological & pharmaceutical bulletin 20031201

Title: Acute lung injury in 2003.

Journal: Acta pharmacologica Sinica 20031201

Title: Successful treatment of dandruff with 1.5% ciclopirox olamine shampoo in Korea.

Journal: The Journal of dermatological treatment 20031201

Title: Multiple mechanisms account for variation in base-line sensitivity to azole fungicides in field isolates of Mycosphaerella graminicola.

Journal: Pest management science 20031201

Title: Liver cirrhosis developed after ketoconazole-induced acute hepatic injury.

Journal: Journal of gastroenterology and hepatology 20031201

Title: Clofibrate, a peroxisome-proliferator, enhances reverse cholesterol transport through cytochrome P450 activation and oxysterol generation.

Journal: The Tohoku journal of experimental medicine 20031201

Title: New triterpene glycosides from the stems of Anomospermum grandifolium.

Journal: Journal of natural products 20031201

Title: Identification of the human cytochrome P450s responsible for the in vitro metabolism of a leukotriene B4 receptor antagonist, CP-195,543.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20031201

Title: Emerging systemic pharmacologic approaches in acute respiratory distress syndrome.

Journal: Respiratory care clinics of North America 20031201

Title: Cutaneous blastomycosis presenting as non-healing ulcer and responding to oral ketoconazole.

Journal: Dermatology online journal 20031201

Title: Clinical strategies in the management of biochemical recurrence after radical prostatectomy.

Journal: Clinical prostate cancer 20031201

Title: Candidiasis (vulvovaginal).

Journal: Clinical evidence 20031201

Title: Stripping voltammetric and polarographic techniques for the determination of anti-fungal ketoconazole on the mercury electrode.

Journal: Journal of pharmaceutical and biomedical analysis 20031124

Title: Threshold for antiproliferative and proapoptotic activity of ttaxol in HepG2 cells expressing human CYP3A4: effect of P-glycoprotein transporters.

Journal: Pharmacology 20031101

Title: Pharmacokinetic and pharmacodynamic interactions of oral midazolam with ketoconazole, fluoxetine, fluvoxamine, and nefazodone.

Journal: Journal of clinical pharmacology 20031101

Title: Docetaxel and ketoconazole in advanced hormone-refractory prostate carcinoma: a phase I and pharmacokinetic study.

Journal: Cancer 20031101

Title: Fungal infection of sutureless self-sealing incision for cataract surgery.

Journal: Ophthalmology 20031101

Title: A double-blind, randomized, placebo-controlled study to assess the efficacy of ketoconazole for reducing the risk of ovarian hyperstimulation syndrome.

Journal: Fertility and sterility 20031101

Title: Ketoconazole alters cyclosporine pharmacokinetic profile and may predispose to acute rejection.

Journal: Transplantation proceedings 20031101

Title: Unintentional rechallenge resulting in a causative relationship between ketoconazole and acute liver injury.

Journal: International journal of clinical practice 20031101

Title: Identification and prediction of promiscuous aggregating inhibitors among known drugs.

Journal: Journal of medicinal chemistry 20031009

Title: Ketoconazole-induced neurologic sequelae.

Journal: Veterinary and human toxicology 20031001

Title: Ketoconazole and lopinavir/ritonavir coadministration: boosting beyond boosting.

Journal: AIDS research and human retroviruses 20031001

Title: Antifungal pharmacotherapy for neonatal candidiasis.

Journal: Seminars in perinatology 20031001

Title: Fungal dermatitis with olanzapine in schizophrenia.

Journal: Canadian journal of psychiatry. Revue canadienne de psychiatrie 20031001

Title: Clotrimazole, ketoconazole, and clodinafop-propargyl inhibit the in vitro growth of Babesia bigemina and Babesia bovis (Phylum Apicomplexa).

Journal: Parasitology 20031001

Title: Lem3p is essential for the uptake and potency of alkylphosphocholine drugs, edelfosine and miltefosine.

Journal: The Journal of biological chemistry 20030919

Title: Genome-wide expression profiling of the response to polyene, pyrimidine, azole, and echinocandin antifungal agents in Saccharomyces cerevisiae.

Journal: The Journal of biological chemistry 20030912

Title: Effect of ketoconazole on venlafaxine plasma concentrations in extensive and poor metabolisers of debrisoquine.

Journal: European journal of clinical pharmacology 20030901

Title: The effect of ketoconazole and diltiazem on oestrogen metabolism in postmenopausal women after single dose oestradiol treatment.

Journal: British journal of clinical pharmacology 20030901

Title: Application of compartmental modeling to an examination of in vitro intestinal permeability data: assessing the impact of tissue uptake, P-glycoprotein, and CYP3A.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20030901

Title: Metabolism and elimination of quinine in healthy volunteers.

Journal: European journal of clinical pharmacology 20030901

Title: Antileishmanial activities of dihydrochalcones from piper elongatum and synthetic related compounds. Structural requirements for activity.

Journal: Bioorganic & medicinal chemistry 20030901

Title: Long-term results of treatment in patients with ACTH-secreting pituitary macroadenomas.

Journal: European journal of endocrinology 20030901

Title: Disseminated paracoccidioidomycosis: correlation between clinical and in vitro resistance to ketoconazole and trimethoprim sulphamethoxazole.

Journal: Mycoses 20030901

Title: A red rash on the face.

Journal: The Journal of family practice 20030901

Title: Gastric function in the elderly: effects on absorption of ketoconazole.

Journal: Journal of clinical pharmacology 20030901

Title: Limited utility of cyclosporine C2 monitoring in heart transplant recipients receiving ketoconazole.

Journal: Transplantation proceedings 20030901

Title: Effect of antifungal drugs on pathogenic Naegleria spp isolated from natural water sources.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20030901

Title: Fluorine substitution can block CYP3A4 metabolism-dependent inhibition: identification of (S)-N-[1-(4-fluoro-3- morpholin-4-ylphenyl)ethyl]-3- (4-fluorophenyl)acrylamide as an orally bioavailable KCNQ2 opener devoid of CYP3A4 metabolism-dependent inhibition.

Journal: Journal of medicinal chemistry 20030828

Title: [Therapeutic safety of antimycotics in the treatment of systemic fungal infections].

Journal: Orvosi hetilap 20030824

Title: Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.

Journal: Bioorganic & medicinal chemistry letters 20030818

Title: Substituent effect on the reductive N-dearylation of 3-(indol-1-yl)-1,2-benzisoxazoles by rat liver microsomes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20030801

Title: Quantitative determination of some pharmaceutical piperazine derivatives through complexation with iron(III) chloride.

Journal: Farmaco (Societa chimica italiana : 1989) 20030801

Title: Hepatotoxicity and toxicokinetics of ketoconazole in rabbits.

Journal: Acta pharmacologica Sinica 20030801

Title: In vitro susceptibility testing of ciclopirox, terbinafine, ketoconazole and itraconazole against dermatophytes and nondermatophytes, and in vitro evaluation of combination antifungal activity.

Journal: The British journal of dermatology 20030801

Title: Activities of therapeutic agents against Naegleria fowleri in vitro and in a mouse model of primary amebic meningoencephalitis.

Journal: The Journal of parasitology 20030801

Title: Selectivities of human cytochrome P450 inhibitors toward rat P450 isoforms: study with cDNA-expressed systems of the rat.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20030701

Title: In vitro metabolism of midazolam, triazolam, nifedipine, and testosterone by human liver microsomes and recombinant cytochromes p450: role of cyp3a4 and cyp3a5.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20030701

Title: Cyclosporin C(2) and C(0) concentration monitoring in stable, long-term heart transplant recipients receiving metabolic inhibitors.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20030701

Title: The use of oral antifungal agents to treat onychomycosis.

Journal: Dermatologic clinics 20030701

Title: Evaluation of different calorimetric methods to determine the glass transition temperature and molecular mobility below T(g) for amorphous drugs.

Journal: International journal of pharmaceutics 20030618

Title: Involvement of CYP3A4, CYP2C8, and CYP2D6 in the metabolism of (R)- and (S)-methadone in vitro.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20030601

Title: Comparative efficacies of oral ketoconazole and terbinafine for reducing Malassezia population sizes on the skin of Basset Hounds.

Journal: Veterinary dermatology 20030601

Title: Variations in color.

Journal: The Journal of family practice 20030601

Title: Gender differences in microsomal metabolic activation of hepatotoxic clivorine in rat.

Journal: Chemical research in toxicology 20030601

Title: Influence of drugs interacting with CYP3A4 on the pharmacokinetics, pharmacodynamics, and safety of the prandial glucose regulator repaglinide.

Journal: Journal of clinical pharmacology 20030601

Title: Antifungal compounds from Zanthoxylum chiloperone var. angustifolium.

Journal: Phytotherapy research : PTR 20030601

Title: Coadministration of tacrolimus and ketoconazole in renal transplant recipients: cost analysis and review of metabolic effects.

Journal: Transplantation proceedings 20030601

Title: Lithium gluconate 8% vs ketoconazole 2% in the treatment of seborrhoeic dermatitis: a multicentre, randomized study.

Journal: The British journal of dermatology 20030601

Title: Clotrimazole, ketoconazole, and clodinafop-propargyl as potent growth inhibitors of equine Babesia parasites during in vitro culture.

Journal: The Journal of parasitology 20030601

Title: Candidiasis (vulvovaginal).

Journal: Clinical evidence 20030601

Title: Identification of the cytochrome P450 enzymes involved in the N-oxidation of voriconazole.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20030501

Title: Expression of the human CYP3A4 gene in the small intestine of transgenic mice: in vitro metabolism and pharmacokinetics of midazolam.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20030501

Title: Quinine 3-hydroxylation as a biomarker reaction for the activity of CYP3A4 in man.

Journal: European journal of clinical pharmacology 20030501

Title: Anti-Aspergillus activities of plant essential oils and their combination effects with ketoconazole or amphotericin B.

Journal: Archives of pharmacal research 20030501

Title: Effectiveness and tolerability of a standardized phytodrug derived from Solanum chrysotrichum on Tinea pedis: a controlled and randomized clinical trial.

Journal: Planta medica 20030501

Title: Modulatory effect of cAMP on fungal ergosterol level and inhibitory activity of azole drugs.

Journal: Canadian journal of microbiology 20030501

Title: Comparison of in vitro P-glycoprotein screening assays: recommendations for their use in drug discovery.

Journal: Journal of medicinal chemistry 20030424

Title: Validation of an HPLC method on short columns to assay ketoconazole and formaldehyde in shampoo.

Journal: Journal of pharmaceutical and biomedical analysis 20030424

Title: Production of progesterone from de novo-synthesized cholesterol in cumulus cells and its physiological role during meiotic resumption of porcine oocytes.

Journal: Biology of reproduction 20030401

Title: Demonstration of UVB-induced synthesis of 1 alpha,25-dihydroxyvitamin D3 (calcitriol) in human skin by microdialysis.

Journal: Archives of dermatological research 20030401

Title: Interaction between ketoconazole and almotriptan in healthy volunteers.

Journal: Journal of clinical pharmacology 20030401

Title: Fluorescent substrates of sister-P-glycoprotein (BSEP) evaluated as markers of active transport and inhibition: evidence for contingent unequal binding sites.

Journal: Pharmaceutical research 20030401

Title: Differential metabolism of midazolam in mouse liver and intestine microsomes: a comparison of cytochrome P450 activity and expression.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20030401

Title: Hepatotoxicity of ketoconazole in Sprague-Dawley rats: glutathione depletion, flavin-containing monooxygenases-mediated bioactivation and hepatic covalent binding.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20030401

Title: Effects of novel 17alpha-hydroxylase/C17, 20-lyase (P450 17, CYP 17) inhibitors on androgen biosynthesis in vitro and in vivo.

Journal: The Journal of steroid biochemistry and molecular biology 20030401

Title: High-content profiling of drug-drug interactions: cellular targets involved in the modulation of microtubule drug action by the antifungal ketoconazole.

Journal: Journal of biomolecular screening 20030401

Title: Retinoic acid metabolism inhibition by 3-azolylmethyl-1H-indoles and 2, 3 or 5-(alpha-azolylbenzyl)-1H-indoles.

Journal: Journal of enzyme inhibition and medicinal chemistry 20030401

Title: Prednisone metabolism in recipients of kidney or liver transplants and in lung recipients receiving ketoconazole.

Journal: Transplantation 20030327

Title: Enhancement of moxidectin bioavailability in lamb by a natural flavonoid: quercetin.

Journal: Veterinary parasitology 20030325

Title: Randomized, multicenter, phase II trial of two multicomponent regimens in androgen-independent prostate cancer.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030301

Title: Metabolism and metabolic inhibition of cilnidipine in human liver microsomes.

Journal: Acta pharmacologica Sinica 20030301

Title: Apparent mechanism-based inhibition of human CYP3A in-vitro by lopinavir.

Journal: The Journal of pharmacy and pharmacology 20030301

Title: [Nosocomial urinary infection due to Trichosporon asahii. First two cases in Chile].

Journal: Revista iberoamericana de micologia 20030301

Title: [Post traumatic subcutaneous mycosis due to Fusarium solani].

Journal: Revista iberoamericana de micologia 20030301

Title: Terbinafine effectiveness in ketoconazole-resistant mucocutaneous candidasis in polyglandular autoimmune syndrome type 1.

Journal: The Journal of the Association of Physicians of India 20030301

Title: Roles of human liver cytochrome P450 3A4 and 1A2 enzymes in the oxidation of myristicin.

Journal: Toxicology letters 20030203

Title: Rhabdomyolysis from cytochrome p-450 interaction of ketoconazole and simvastatin in prostate cancer.

Journal: The Journal of urology 20030201

Title: A murine model of coccidioidal meningitis.

Journal: The Journal of infectious diseases 20030201

Title: The effect of ketoconazole on the in vivo intestinal permeability of fexofenadine using a regional perfusion technique.

Journal: British journal of clinical pharmacology 20030201

Title: Steroid synthesis inhibition with ketoconazole and its effect upon the regulation of the hypothalamus-pituitary-adrenal system in healthy humans.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030201

Title: Efficacy and safety of low-dose ketoconazole (50 mg) to reduce the cost of cyclosporine in renal allograft recipients.

Journal: Transplantation proceedings 20030201

Title: Antifungal agents of use in animal health--chemical, biochemical and pharmacological aspects.

Journal: Journal of veterinary pharmacology and therapeutics 20030201

Title: Coccidiomycosis in a dog.

Journal: The Canadian veterinary journal = La revue veterinaire canadienne 20030201

Title: [How to manage seborrheic dermatitis].

Journal: Revue medicale de Liege 20030201

Title: Identification of novel enzyme-prodrug combinations for use in cytochrome P450-based gene therapy for cancer.

Journal: Archives of biochemistry and biophysics 20030101

Title: Oxidative activation of acylguanidine prodrugs: intestinal presystemic activation in rats limits absorption and can be inhibited by co-administration of ketoconazole.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20030101

Title: Lack of effect of ketoconazole on the pharmacokinetics of rosuvastatin in healthy subjects.

Journal: British journal of clinical pharmacology 20030101

Title: Antifungal activity of the essential oil of Agastache rugosa Kuntze and its synergism with ketoconazole.

Journal: Letters in applied microbiology 20030101

Title: A case of infantile acne due to pityrosporum.

Journal: Pediatric dermatology 20030101

Title: [Conjunctival infection due to penicillium SP].

Journal: Archivos de la Sociedad Espanola de Oftalmologia 20030101

Title: [Molecular biological analysis of Tinea faciei caused by a clinically anomalous strain of Trichophyton mentagrophytes].

Journal: Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology 20030101

Title: The effect of granisetron on in vitro metabolism of paclitaxel and docetaxel.

Journal: Cancer journal (Sudbury, Mass.) 20030101

Title: Seborrheic dermatitis today, gone tomorrow? The link between the biocene and treatment.

Journal: Dermatology (Basel, Switzerland) 20030101

Title: Randomized, open-labeled, non-inferiority study between ciclopiroxolamine 1% cream and ketoconazole 2% foaming gel in mild to moderate facial seborrheic dermatitis.

Journal: Dermatology (Basel, Switzerland) 20030101

Title: Ketoconazole in the treatment of prostate cancer.

Journal: Clinical journal of oncology nursing 20030101

Title: Treatment of cutaneous leishmaniasis with ketoconazole cream.

Journal: The Journal of dermatological treatment 20030101

Title: Framing the future of antifungals in atopic dermatitis.

Journal: Dermatology (Basel, Switzerland) 20030101

Title: Tolerance to antidepressant treatment may be overcome by ketoconazole. Report of two cases.

Journal: Journal of psychiatric research 20030101

Title: Azoles for allergic bronchopulmonary aspergillosis associated with asthma.

Journal: The Cochrane database of systematic reviews 20030101

Title: [Madura foot (mycetoma)].

Journal: Vestnik khirurgii imeni I. I. Grekova 20030101

Title: [Finger agenesis after in utero exposure to ketoconazole: a case report].

Journal: Therapie 20030101

Title: Ketoconazole foam--connetics: connetics ketoconazole foam.

Journal: Drugs in R&D 20030101

Title: In vitro drug-drug interactions with perospirone and concomitantly administered drugs in human liver microsomes.

Journal: European journal of drug metabolism and pharmacokinetics 20030101

Title: [Vaginal candidiasis--treatment protocols using miconazole and fluconazole].

Journal: Akusherstvo i ginekologiia 20030101

Title: Oral manifestations of paracoccidioidomycosis. Report of 21 cases from Argentina.

Journal: Mycoses 20030101

Title: Fungal peritonitis in 15 patients on continuous ambulatory peritoneal dialysis (CAPD).

Journal: Mycoses 20030101

Title: Synthesis, in vitro/in vivo antifungal evaluation and structure-activity relationship study of 3(2H)-pyridazinones.

Journal: Arzneimittel-Forschung 20030101

Title: Occurrence of dermatomycoses and in-vitro therapeutic efficacy of three antifungal drugs on the growth of Epidermophyton floccosum.

Journal: Mycopathologia 20030101

Title: [Investigation of quantitative and species composition and antifungal drug susceptibility of yeasts isolated from patients with generalized periodontitis complicated by candidosis].

Journal: Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993) 20030101

Title: [Madura's foot (mycetoma)].

Journal: Chirurgia (Bucharest, Romania : 1990) 20030101

Title: Medical treatment of hyperadrenocorticism in the dog.

Journal: Australian veterinary journal 20030101

Title: Protective effect of ketoconazole against experimentally induced gastric ulcers in rats.

Journal: Research communications in molecular pathology and pharmacology 20030101

Title: [In vitro sensitivity of Histoplasma capsulatum var. capsulatum to amphotericin B, ketoconazole, itroconazole and fluconazole].

Journal: Revista cubana de medicina tropical 20030101

Title: Separation of antifungal chiral drugs by SFC and HPLC: a comparative study.

Journal: Journal of biochemical and biophysical methods 20021231

Title: Pharmacophore model of drugs involved in P-glycoprotein multidrug resistance: explanation of structural variety (hypothesis).

Journal: Journal of medicinal chemistry 20021219

Title: Mathematical modelling of antifungal action.

Journal: Mycoses 20021201

Title: [Observations on the efficacy of Botai ointment in treating dermatosis common among armed forces receiving at-sea training].

Journal: Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20021201

Title: Application of semisimultaneous midazolam administration for hepatic and intestinal cytochrome P450 3A phenotyping.

Journal: Clinical pharmacology and therapeutics 20021201

Title: Prevalence and antifungal susceptibilities of yeast isolates during one year at a university hospital in Turkey.

Journal: Journal of chemotherapy (Florence, Italy) 20021201

Title: Inhibition of the microsomal metabolism of 1,8-cineole in the common brushtail possum (Trichosurus vulpecula) by terpenes and other chemicals.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20021201

Title: National Cancer Institute intramural approach to advanced prostate cancer.

Journal: Clinical prostate cancer 20021201

Title: Triiodide ion and alizarin red S as two new reagents for the determination of clotrimazole and ketoconazole.

Journal: Journal of pharmaceutical and biomedical analysis 20021107

Title: Paracoccidioidomycosis: report of 2 cases mimicking squamous cell carcinoma.

Journal: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20021101

Title: Pharmacokinetics and electrocardiographic pharmacodynamics of artemether-lumefantrine (Riamet) with concomitant administration of ketoconazole in healthy subjects.

Journal: British journal of clinical pharmacology 20021101

Title: Chromatographic determination of clotrimazole, ketoconazole and fluconazole in pharmaceutical formulations.

Journal: Farmaco (Societa chimica italiana : 1989) 20021101

Title: Corticosteroids and pregnancy.

Journal: Seminars in reproductive medicine 20021101

Title: Synthesis of novel water soluble benzylazolium prodrugs of lipophilic azole antifungals.

Journal: Bioorganic & medicinal chemistry letters 20021007

Title: Sirolimus oral absorption in rats is increased by ketoconazole but is not affected by D-alpha-tocopheryl poly(ethylene glycol 1000) succinate.

Journal: The Journal of pharmacology and experimental therapeutics 20021001

Title: Interaction of cytochrome P450 3A inhibitors with P-glycoprotein.

Journal: The Journal of pharmacology and experimental therapeutics 20021001

Title: Preclinical activity of ketoconazole in combination with calcitriol or the vitamin D analogue EB 1089 in prostate cancer cells.

Journal: The Journal of urology 20021001

Title: Efficacy of ozonized sunflower oil in the treatment of tinea pedis.

Journal: Mycoses 20021001

Title: Vulvovaginal candidiasis.

Journal: BMJ (Clinical research ed.) 20020914

Title: Expression of paclitaxel-inactivating CYP3A activity in human colorectal cancer: implications for drug therapy.

Journal: British journal of cancer 20020909

Title: Putative role of the orphan nuclear receptor SXR (steroid and xenobiotic receptor) in the mechanism of CYP3A4 inhibition by xenobiotics.

Journal: The Journal of biological chemistry 20020906

Title: Macrophage plasma membrane cholesterol contributes to Brucella abortus infection of mice.

Journal: Infection and immunity 20020901

Title: In vitro, pharmacokinetic, and pharmacodynamic interactions of ketoconazole and midazolam in the rat.

Journal: The Journal of pharmacology and experimental therapeutics 20020901

Title: Characterization of quinidine 3-hydroxylation as a probe for the CYP 3A enzyme using a novel capillary electrophoresis technique.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20020901

Title: Evaluation of a 15-day screening assay using intact male rats for identifying steroid biosynthesis inhibitors and thyroid modulators.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20020901

Title: Ketoconazole suppresses interleukin-4 plus anti-CD40-induced IgE class switching in surface IgE negative B cells from patients with atopic dermatitis.

Journal: The Journal of investigative dermatology 20020901

Title: Azole susceptibility patterns and genetic relationship among oral Candida strains isolated in the era of highly active antiretroviral therapy.

Journal: Journal of acquired immune deficiency syndromes (1999) 20020901

Title: Design, synthesis, and biological evaluation of aryloxyethyl thiocyanate derivatives against Trypanosoma cruzi.

Journal: Journal of medicinal chemistry 20020829

Title: Low dose ketoconazole with replacement doses of hydrocortisone in patients with progressive androgen independent prostate cancer.

Journal: The Journal of urology 20020801

Title: Corneal ulcer caused by the new fungal species Sarcopodium oculorum.

Journal: Journal of clinical microbiology 20020801

Title: Ketoconazole potentiates the antitumor effects of nocodazole: In vivo therapy for human tumor xenografts in nude mice.

Journal: Molecular carcinogenesis 20020801

Title: In vivo measurement of human skin absorption of topically applied substances by a photoacoustic technique.

Journal: Physiological measurement 20020801

Title: Comparative efficacy of various treatment regimens for androgenetic alopecia in men.

Journal: The Journal of dermatology 20020801

Title: Randomized trial with itraconazole, ketoconazole and sulfadiazine in paracoccidioidomycosis.

Journal: Medical mycology 20020801

Title: Role of ketoconazole treatment in urinary-free cortisol-to-cortisone and tetrahydrocortisol-to-tetrahydrocortisone ratios in nonectopic Cushing's syndrome.

Journal: Endocrine 20020801

Title: Modulation of irinotecan metabolism by ketoconazole.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020715

Title: Determination of ketoconazole in human plasma by high-performance liquid chromatography-tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020705

Title: HPLC-MS/MS analysis of the products generated from all-trans-retinoic acid using recombinant human CYP26A.

Journal: Journal of lipid research 20020701

Title: Application of modeling and simulation to integrate clinical pharmacology knowledge across a new drug application.

Journal: International journal of clinical pharmacology and therapeutics 20020701

Title: Ketoconazole and kids.

Journal: Postgraduate medicine 20020701

Title: [Tinea].

Journal: Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20020701

Title: Ketoconazole suppresses prostaglandin E(2)-induced cyclooxygenase-2 expression in human epidermoid carcinoma A-431 cells.

Journal: The Journal of investigative dermatology 20020701

Title: Protothecal colitis in a German shepherd dog.

Journal: Australian veterinary journal 20020701

Title: Double-blind antiglucocorticoid treatment in schizophrenia and schizoaffective disorder: a pilot study.

Journal: The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20020701

Title: Antifungal agents. 10. New derivatives of 1-[(aryl)[4-aryl-1H-pyrrol-3-yl]methyl]-1H-imidazole, synthesis, anti-candida activity, and quantitative structure-analysis relationship studies.

Journal: Journal of medicinal chemistry 20020620

Title: New regulators of drug sensitivity in the family of yeast zinc cluster proteins.

Journal: The Journal of biological chemistry 20020614

Title: Cutaneous candidiasis in a dog caused by Candida guilliermondii.

Journal: The Veterinary record 20020608

Title: Simultaneous determination of ketoconazole and formaldehyde in a shampoo: liquid chromatography method development and validation.

Journal: Journal of chromatography. A 20020607

Title: Expression profiling in squamous carcinoma cells reveals pleiotropic effects of vitamin D3 analog EB1089 signaling on cell proliferation, differentiation, and immune system regulation.

Journal: Molecular endocrinology (Baltimore, Md.) 20020601

Title: Single- and multiple-dose pharmacokinetics of bosentan and its interaction with ketoconazole.

Journal: British journal of clinical pharmacology 20020601

Title: Oral treatments for toenail onychomycosis: a systematic review.

Journal: Archives of dermatology 20020601

Title: A randomised, single-blind, single-centre clinical trial to evaluate comparative clinical efficacy of shampoos containing ciclopirox olamine (1.5%) and salicylic acid (3%), or ketoconazole (2%, Nizoral) for the treatment of dandruff/seborrhoeic dermatitis.

Journal: The Journal of dermatological treatment 20020601

Title: Fluconazole versus ketoconazole in the treatment of tinea versicolor.

Journal: The Journal of dermatological treatment 20020601

Title: In vitro characterization of the inhibitory effects of ketoconazole on metabolic activities of cytochrome P-450 in canine hepatic microsomes.

Journal: American journal of veterinary research 20020601

Title: 7-Benzyloxyquinoline oxidation by P450eryF A245T: finding of a new fluorescent substrate probe.

Journal: Chemical research in toxicology 20020601

Title: Effects of ketoconazole on progesterone and cAMP production in MA-10 mouse Leydig tumor cells.

Journal: Biological & pharmaceutical bulletin 20020601

Title: [Intranasal rhinosporidiosis: presentation of the 1st case seen in the Congo].

Journal: Bulletin de la Societe de pathologie exotique (1990) 20020601

Title: Chronic administration of verapamil, ketoconazole and carbamazepine: impact on immunological parameters.

Journal: International journal of pharmaceutics 20020515

Title: Three-dimensional quantitative structure-activity relationships of inhibitors of P-glycoprotein.

Journal: Molecular pharmacology 20020501

Title: Potential role for the hypothalamo-pituitary-adrenal axis in the conditioned reinforcer-induced reinstatement of extinguished cocaine seeking in rats.

Journal: Psychopharmacology 20020501

Title: Oral FK 506 blood levels are elevated in pig short bowel model: further investigations with co-administration of an intestinal CYP3A4 inhibitor.

Journal: Transplantation proceedings 20020501

Title: [Candida infection of the skin and mucous membranes still a topic. Administering azoles with clinical understanding].

Journal: MMW Fortschritte der Medizin 20020409

Title: Effects of 3-MeSO2-DDE and some CYP inhibitors on glucocorticoid steroidogenesis in the H295R human adrenocortical carcinoma cell line.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20020401

Title: Human CYP3A4 and the metabolism of nefazodone and hydroxynefazodone by human liver microsomes and heterologously expressed enzymes.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20020401

Title: Ketoconazole increases cocaine and opioid use in methadone maintained patients.

Journal: Drug and alcohol dependence 20020401

Title: In vitro inhibition of pimozide N-dealkylation by selective serotonin reuptake inhibitors and azithromycin.

Journal: Journal of clinical psychopharmacology 20020401

Title: Antimicrobial activities of a new schizozygane indoline alkaloid from Schizozygia coffaeoides and the revised structure of isoschizogaline.

Journal: Journal of natural products 20020401

Title: Black-dot tinea capitis. Patchy hair loss is common in pediatric patients.

Journal: Postgraduate medicine 20020401

Title: Clinical comparison of the efficacy and tolerability of once daily Canesten with twice daily Nizoral (clotrimazole 1% cream vs. ketoconazole 2% cream) during a 28-day topical treatment of interdigital tinea pedis.

Journal: Mycoses 20020401

Title: Case report. Nattrassia mangiferae endophthalmitis.

Journal: Mycoses 20020401

Title: Chronic mucocutaneous candidiasis.

Journal: JAAPA : official journal of the American Academy of Physician Assistants 20020401

Title: Cyclosporin and ketoconazole interaction for treatment of perianal fistulas in the dog.

Journal: Australian veterinary journal 20020401

Title: Superficial mycosis superimposing on isolated lichen planus of the lip: a case report and review of the literature.

Journal: Cutis 20020401

Title: [Identification and antifungal susceptibility of Candida spp isolated from invasive mycoses. Influence of growth inhibition percentage to determine minimal inhibitory concentration].

Journal: Revista medica de Chile 20020401

Title: Cyclosporine and ketoconazole for the treatment of perianal fistulas in dogs.

Journal: Journal of the American Veterinary Medical Association 20020401

Title: Simple high-performance liquid chromatography method for the simultaneous determination of ketoconazole and piperine in rat plasma and hepatocyte culture.

Journal: Journal of chromatography. A 20020308

Title: Effect of antifungal azoles on the heme detoxification system of malarial parasite.

Journal: Journal of biochemistry 20020301

Title: Effect of oral ketoconazole on first-pass effect of nifedipine after oral administration in dogs.

Journal: Journal of pharmaceutical sciences 20020301

Title: Minimal effect of ketoconazole on cyclosporine (SangCyA) oral absorption and first-pass metabolism in rats: evidence of a significant vehicle effect on SangCyA absorption.

Journal: Biopharmaceutics & drug disposition 20020301

Title: Multicenter Brazilian study of oral Candida species isolated from AIDS patients.

Journal: Memorias do Instituto Oswaldo Cruz 20020301

Title: Cytochrome P450 enzymes contributing to demethylation of maprotiline in man.

Journal: Pharmacology & toxicology 20020301

Title: Identification of the human P450 enzymes involved in the in vitro metabolism of the synthetic steroidal hormones Org 4060 and Org 30659.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20020201

Title: Infectious keratitis in orthokeratology.

Journal: Clinical & experimental ophthalmology 20020201

Title: Ring substituted 3-phenyl-1-(2-pyrazinyl)-2-propen-1-ones as potential photosynthesis-inhibiting, antifungal and antimycobacterial agents.

Journal: Farmaco (Societa chimica italiana : 1989) 20020201

Title: Effect of multiple dosing of ketoconazole on pharmacokinetics of midazolam, a cytochrome P-450 3A substrate in beagle dogs.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20020101

Title: Peppermint oil enhances cyclosporine oral bioavailability in rats: comparison with D-alpha-tocopheryl poly(ethylene glycol 1000) succinate (TPGS) and ketoconazole.

Journal: Journal of pharmaceutical sciences 20020101

Title: CYP3A4-mediated hepatic metabolism of the HIV-1 protease inhibitor saquinavir in vitro.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20020101

Title: Interventions for treating oral candidiasis for patients with cancer receiving treatment.

Journal: The Cochrane database of systematic reviews 20020101

Title: Comparison of two methods for antifungal susceptibility testing of Trichophyton rubrum.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20020101

Title: Mycetoma caused by Fusarium solani with osteolytic lesions on the hand: case report.

Journal: Mycopathologia 20020101

Title: A unique case of bladder mycetoma.

Journal: Tropical doctor 20020101

Title: Pathology case of the month. Chronic leg ulcer in a missionary worker. Cutaneous leishmaniasis.

Journal: The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society 20020101

Title: Ectopic ACTH-syndrome due to a thymic carcinoid tumor.

Journal: Acta clinica Belgica 20020101

Title: More economical use of cyclosporine through combination drug therapy.

Journal: Journal of the American Animal Hospital Association 20020101

Title: Sustained release bioadhesive effervescent ketoconazole microcapsules tabletted for vaginal delivery.

Journal: Journal of microencapsulation 20020101

Title: Post-antifungal effect and effects of sub-MIC concentrations on previously treated Candida spp.: influence of exposure time and concentration.

Journal: Scandinavian journal of infectious diseases 20020101

Title: Euclidean and fractal computer-assisted corneofungimetry: a comparison of 2% ketoconazole and 1% terbinafine topical formulations.

Journal: Dermatology (Basel, Switzerland) 20020101

Title: A case of confluent and reticulated papillomatosis responsive to ketoconazole cream.

Journal: Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology 20020101

Title: A double-blind placebo-controlled study of ketoconazole + desonide gel combination in the treatment of facial seborrheic dermatitis.

Journal: Dermatology (Basel, Switzerland) 20020101

Title: Efficacy and skin tolerability of Saliker in the treatment of dandruff.

Journal: European journal of dermatology : EJD 20020101

Title: Antifungal topical therapy in oral chronic candidosis. A comparative study.

Journal: Medicina oral : organo oficial de la Sociedad Espanola de Medicina Oral y de la Academia Iberoamericana de Patologia y Medicina Bucal 20020101

Title: Desloratadine has no clinically relevant electrocardiographic or pharmacodynamic interactions with ketoconazole.

Journal: Clinical pharmacokinetics 20020101

Title: Ketoconazole potentiates terfenadine-induced apoptosis in human Hep G2 cells through inhibition of cytochrome p450 3A4 activity.

Journal: Journal of cellular biochemistry 20020101

Title: Atopic dermatitis with mononuclear phagocytic activity deficiency.

Journal: Allergologia et immunopathologia 20020101

Title: A multicenter randomized trial of ketoconazole 2% and zinc pyrithione 1% shampoos in severe dandruff and seborrheic dermatitis.

Journal: Skin pharmacology and applied skin physiology 20020101

Title: Efficacy and skin tolerability of saliker in the treatment of dandruff.

Journal: European journal of dermatology : EJD 20020101

Title: Low dose ketoconazole therapy and thyroid functions in rats.

Journal: Acta medica (Hradec Kralove) 20020101

Title: The preventive effect of ketoconazole on experimental metastasis from a human pancreatic carcinoma may be related to its effect on prostaglandin synthesis.

Journal: International journal of gastrointestinal cancer 20020101

Title: Invitro drug sensitivity of Trichophyton species against griseofulvin and ketoconazole.

Journal: Hindustan antibiotics bulletin 20020101

Title: Ectopic adrenocorticotropic hormone syndrome caused by metastatic carcinoma of the prostate: therapeutic response to ketoconazole.

Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20020101

Title: Toward a novel metal-based chemotherapy against tropical diseases. 6. Synthesis and characterization of new copper(II) and gold(I) clotrimazole and ketoconazole complexes and evaluation of their activity against Trypanosoma cruzi.

Journal: Inorganic chemistry 20011231

Title: Fatal aplastic anemia during treatment with ketoconazole.

Journal: The American journal of medicine 20011215

Title: No evidence of oxidant events in amphotericin B cytotoxicity versus L. infantum promastigotes.

Journal: Parasite (Paris, France) 20011201

Title: Novel steroidal pyrimidyl inhibitors of P450 17 (17 alpha-hydroxylase/C17-20-lyase).

Journal: Archiv der Pharmazie 20011201

Title: Effects of ketoconazole on oestrus cycle and convulsant action of pentylenetetrazol in mice.

Journal: Pharmacology & toxicology 20011201

Title: Diazinon is activated by CYP2C19 in human liver.

Journal: Toxicology and applied pharmacology 20011115

Title: Enhanced antifungal activity of ketoconazole by Euphorbia characias latex against Candida albicans.

Journal: Journal of ethnopharmacology 20011101

Title: Quantitative liquid chromatography/mass spectrometry/mass spectrometry warfarin assay for in vitro cytochrome P450 studies.

Journal: Analytical biochemistry 20011101

Title: Importance of inhibin B in the regulation of FSH secretion in the human male.

Journal: The Journal of clinical endocrinology and metabolism 20011101

Title: Effects of azoles on human acute myelogenous leukemia blasts and T lymphocytes derived from acute leukemia patients with chemotherapy-induced cytopenia.

Journal: International immunopharmacology 20011101

Title: Improved responsiveness of PCOS patients to clomiphene after CYP17a inhibitor.

Journal: Journal of assisted reproduction and genetics 20011101

Title: Gene amplification in amphotericin B-resistant Leishmania tarentolae.

Journal: Experimental parasitology 20011101

Title: Relative contribution of CYP3A to amitriptyline clearance in humans: in vitro and in vivo studies.

Journal: Journal of clinical pharmacology 20011001

Title: A clinical case of canine mycotic pneumonia.

Journal: Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20011001

Title: Comparative efficacy of ketoconazole and fluconazole in the treatment of pityriasis versicolor: a one year follow-up study.

Journal: The Journal of dermatology 20011001

Title: Ketoconazole and Flutamide in the treatment of disseminated intravascular clotting from prostate cancer: a case report and review.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20011001

Title: Effect of pharmacotechnical design on the in vitro interaction of ketoconazole tablets with non-systemic antacids.

Journal: International journal of pharmaceutics 20010911

Title: [Spondylodiscitis due to Histoplasma duboisii. Report of two cases and review of the literature].

Journal: Neuro-Chirurgie 20010901

Title: 7-Deoxyloganin 7-hydroxylase in Lonicera japonica cell cultures.

Journal: Phytochemistry 20010901

Title: Post-antifungal effect of polyene, azole and DNA-analogue agents against oral Candida albicans and Candida tropicalis isolates in HIV disease.

Journal: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20010901

Title: A simple algorithm for designing group sequential clinical trials.

Journal: Biometrics 20010901

Title: Lack of effect of reboxetine on cardiac repolarization.

Journal: Clinical pharmacology and therapeutics 20010901

Title: Medical treatment of canine pituitary-dependent hyperadrenocorticism (Cushing's disease).

Journal: The Veterinary clinics of North America. Small animal practice 20010901

Title: Severe respiratory failure secondary to Cushing's myopathy.

Journal: Journal of endocrinological investigation 20010901

Title: Oral histoplasmosis.

Journal: The Journal of the Association of Physicians of India 20010901

Title: Comparative study of the efficacy of oral ketoconazole with intra-lesional meglumine antimoniate (Glucantime) for the treatment of cutaneous leishmaniasis.

Journal: The Journal of dermatological treatment 20010901

Title: Pulmonary candidiasis caused by Candida albicans in a Greek tortoise (Testudo graeca) and treatment with intrapulmonary amphotericin B.

Journal: Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20010901

Title: Cyclosporin immunosuppression of sheep: pharmacokinetics and allograft survival.

Journal: Veterinary immunology and immunopathology 20010830

Title: Primary culture system of adrenocortical cells from dogs to evaluate direct effects of chemicals on steroidogenesis.

Journal: Toxicology 20010828

Title: 3-Phenyl-5-acyloxymethyl-2H,5H-furan-2-ones: synthesis and biological activity of a novel group of potential antifungal drugs.

Journal: Journal of medicinal chemistry 20010816

Title: Ketoconazole-induced conformational changes in the active site of cytochrome P450eryF.

Journal: Journal of molecular biology 20010803

Title: State-dependent block of rabbit vascular smooth muscle delayed rectifier and Kv1.5 channels by inhibitors of cytochrome P450-dependent enzymes.

Journal: The Journal of pharmacology and experimental therapeutics 20010801

Title: Rationale for combination ketoconazole/ vitamin D treatment of prostate cancer.

Journal: Urology 20010801

Title: Modulation of the cytochrome P450-mediated metabolism of ifosfamide by ketoconazole and rifampin.

Journal: Clinical pharmacology and therapeutics 20010801

Title: A systematic review of the effectiveness of antifungal drugs for the prevention and treatment of oropharyngeal candidiasis in HIV-positive patients.

Journal: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20010801

Title: Application of capillary zone electrophoresis with off-line solid-phase extraction to in vitro metabolism studies of antifungals.

Journal: Electrophoresis 20010801

Title: Ketoconazole suppresses food restriction-induced increases in heroin self-administration in rats: sex differences.

Journal: Experimental and clinical psychopharmacology 20010801

Title: Characterization of amorphous ketoconazole using modulated temperature differential scanning calorimetry.

Journal: Journal of pharmaceutical sciences 20010801

Title: Arthroderma benhamiae infection in a rabbit.

Journal: The Journal of veterinary medical science 20010801

Title: [Modern local therapy of foot mycoses in servicemen].

Journal: Voenno-meditsinskii zhurnal 20010801

Title: Adsorptive behavior and electrochemical determination of the anti-fungal agent ketoconazole.

Journal: Fresenius' journal of analytical chemistry 20010801

Title: Uptake of Malassezia furfur by human dermal fibroblasts: effect of ketoconazole and cytoskeleton inhibitors.

Journal: Archives of dermatological research 20010801

Title: Heterogeneity in antifungal susceptibility of clones of Candida albicans isolated on single and sequential visits from a HIV-infected southern Chinese cohort.

Journal: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20010701

Title: Effect of an extract of the root of Scutellaria baicalensis and its flavonoids on aflatoxin B1 oxidizing cytochrome P450 enzymes.

Journal: Planta medica 20010701

Title: Ca(2+) transport into an intracellular acidic compartment of Candida parapsilosis.

Journal: FEBS letters 20010629

Title: Application to drug-food interactions of living cells as in vitro model expressing cytochrome P450 activity: enzyme inhibition by lemon juice.

Journal: Talanta 20010621

Title: Oropharyngeal candidiasis in patients with human immunodeficiency virus: correlation of clinical outcome with in vitro resistance, serum azole levels, and immunosuppression.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20010601

Title: Arachidonic acid directly activates members of the mitogen-activated protein kinase superfamily in rabbit proximal tubule cells.

Journal: Kidney international 20010601

Title: Aromatization mediates testosterone's short-term feedback restraint of 24-hour endogenously driven and acute exogenous gonadotropin-releasing hormone-stimulated luteinizing hormone and follicle-stimulating hormone secretion in young men.

Journal: The Journal of clinical endocrinology and metabolism 20010601

Title: Photo quiz. Congenital cutaneous candidiasis.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20010601

Title: Successful treatment of Acanthamoeba meningitis with combination oral antimicrobials.

Journal: The Pediatric infectious disease journal 20010601

Title: Systemic ketoconazole is an effective treatment of atopic dermatitis with IgE-mediated hypersensitivity to yeasts.

Journal: Allergy 20010601

Title: Temporary remission of disseminated paecilomycosis in a German shepherd dog treated with ketoconazole.

Journal: Journal of the South African Veterinary Association 20010601

Title: [In vitro antifungal susceptibility of dematiaceous filamentous fungi using the E-test].

Journal: Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20010601

Title: The effect of gut metabolism on tacrolimus bioavailability in renal transplant recipients.

Journal: Transplantation 20010515

Title: Mechanism of action of anti-proliferative lysophospholipid analogues against the protozoan parasite Trypanosoma cruzi: potentiation of in vitro activity by the sterol biosynthesis inhibitor ketoconazole.

Journal: The Journal of antimicrobial chemotherapy 20010501

Title: Effect of inoculum form on in vitro antifungal susceptibilities of Aspergillus spp.

Journal: The Journal of antimicrobial chemotherapy 20010501

Title: Low salivary cortisol levels and aggressive behavior.

Journal: Archives of general psychiatry 20010501

Title: The interaction of saquinavir (soft gelatin capsule) with ketoconazole, erythromycin and rifampicin: comparison of the effect in healthy volunteers and in HIV-infected patients.

Journal: European journal of clinical pharmacology 20010501

Title: Metabolism of amiodarone (Part III): identification of rabbit cytochrome P450 isoforms involved in the hydroxylation of mono-N-desethylamiodarone.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20010501

Title: [Endemic mycotic infections].

Journal: La Revue du praticien 20010415

Title: Liquid chromatographic determination of ketoconazole, a potent inhibitor of CYP3A4-mediated metabolism.

Journal: Journal of chromatography. B, Biomedical sciences and applications 20010405

Title: Evaluation of the male pubertal onset assay to detect testosterone and steroid biosynthesis inhibitors in CD rats.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20010401

Title: Application of the relative activity factor approach in scaling from heterologously expressed cytochromes p450 to human liver microsomes: studies on amitriptyline as a model substrate.

Journal: The Journal of pharmacology and experimental therapeutics 20010401

Title: Hypokalemia, metabolic alkalosis, and hypertension: Cushing's syndrome in a patient with metastatic prostate adenocarcinoma.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20010401

Title: Pharmacokinetics of cyclosporine in heart transplant recipients receiving metabolic inhibitors.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20010401

Title: Interaction of two novel 14-epivitamin D3 analogs with vitamin D3 receptor-retinoid X receptor heterodimers on vitamin D3 responsive elements.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20010401

Title: Successful treatment of visceral leishmaniasis with allopurinol plus ketoconazole in an infant who developed pancreatitis caused by meglumine antimoniate.

Journal: The Pediatric infectious disease journal 20010401

Title: Ranitidine-related Stevens-Johnson syndrome in patients with severe liver diseases: a report of two cases.

Journal: Journal of gastroenterology and hepatology 20010401

Title: Preparation and physical characterization of alginate microparticles using air atomization method.

Journal: Drug development and industrial pharmacy 20010401

Title: Hard palate perforation: an unusual finding in paracoccidioidomycosis.

Journal: International journal of dermatology 20010401

Title: Drug sensitivity of Candida yeast isolated from patients with allergic diseases.

Journal: Bulletin of experimental biology and medicine 20010401

Title: Treatments for common superficial fungal infections.

Journal: Dermatology nursing 20010401

Title: Coadministration of ketoconazole and cyclosporine for kidney transplant recipients: long-term follow-up and study of metabolic consequences.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20010301

Title: Clinical inquiries. What is the best oral antifungal medication for tinea capitis?

Journal: The Journal of family practice 20010301

Title: A new class of nonsteroidal aromatase inhibitors: design and synthesis of chromone and xanthone derivatives and inhibition of the P450 enzymes aromatase and 17 alpha-hydroxylase/C17,20-lyase.

Journal: Journal of medicinal chemistry 20010301

Title: Treatment for coccidioidomycosis in pregnancy?

Journal: Postgraduate medicine 20010301

Title: Fatal liver failure due to ketoconazole treatment of a girl with Cushing's syndrome.

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20010301

Title: [Ocular parasitoses and mycoses: cases diagnosed in the Central University Hospital of Sfax between 1996 and 1999].

Journal: Bulletin de la Societe de pathologie exotique (1990) 20010301

Title: Effects of ketoconazole on the acquisition of intravenous cocaine self-administration under different feeding conditions in rats.

Journal: Psychopharmacology 20010301

Title: Emedastine-ketoconazole: pharmacokinetic and pharmacodynamic interactions in healthy volunteers.

Journal: International journal of clinical pharmacology and therapeutics 20010301

Title: In vitro/in vivo scaling of alprazolam metabolism by CYP3A4 and CYP3A5 in humans.

Journal: Biopharmaceutics & drug disposition 20010301

Title: Aminoglutethimide, a steroidogenesis inhibitor, abolishes hormonal induction of ornithine decarboxylase in steroidogenic tissues: evidence for its role as cAMP-dependent protein kinase inhibitor.

Journal: Biochemical and biophysical research communications 20010216

Title: Muting of androgen negative feedback unveils impoverished gonadotropin-releasing hormone/luteinizing hormone secretory reactivity in healthy older men.

Journal: The Journal of clinical endocrinology and metabolism 20010201

Title: CYP3A4 is the major CYP isoform mediating the in vitro hydroxylation and demethylation of flunitrazepam.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20010201

Title: Modulation of P450 CYP3A4-dependent metabolism by P-glycoprotein: implications for P450 phenotyping.

Journal: The Journal of pharmacology and experimental therapeutics 20010201

Title: A novel sequence element is involved in the transcriptional regulation of expression of the ERG1 (squalene epoxidase) gene in Saccharomyces cerevisiae.

Journal: European journal of biochemistry 20010201

Title: Lack of effect of a single dose of ketoconazole on the pharmacokinetics of citalopram.

Journal: Pharmacotherapy 20010201

Title: Determination of minumum inhibitory concentrations of Candida species isolated from vaginal swab specimens by using broth macrodilution and E-test.

Journal: Journal of chemotherapy (Florence, Italy) 20010201

Title: Effect of ketoconazole, itraconazole and fluconazole on the gastrointestinal colonization of mice by Candida albicans.

Journal: Journal of chemotherapy (Florence, Italy) 20010201

Title: Ketoconazole in bipolar patients with depressive symptoms: a case series and literature review.

Journal: Bipolar disorders 20010201

Title: Species difference in stereoselective involvement of CYP3A in the mono-N-dealkylation of disopyramide.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20010201

Title: Indications for the involvement of a CYP3A-like iso-enzyme in the metabolism of chlorobornane (Toxaphene) congeners in seals from inhibition studies with liver microsomes.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20010101

Title: Physical stabilisation of amorphous ketoconazole in solid dispersions with polyvinylpyrrolidone K25.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20010101

Title: Meiosis-activating sterol and the maturation of isolated mouse oocytes.

Journal: Biology of reproduction 20010101

Title: The combination of oral amphotericin B with azoles prevents the emergence of resistant Candida species in neutropenic patients.

Journal: British journal of haematology 20010101

Title: Studies on the metabolism of troglitazone to reactive intermediates in vitro and in vivo. Evidence for novel biotransformation pathways involving quinone methide formation and thiazolidinedione ring scission.

Journal: Chemical research in toxicology 20010101

Title: Endogenous lipoid pneumonia associated with undifferentiated connective tissue disease (UCTD).

Journal: Medical science monitor : international medical journal of experimental and clinical research 20010101

Title: [The yeast fungus Malassezia: pathogen, pathogenesis and therapy].

Journal: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20010101

Title: Differential regulation of gonadotropin secretion by testosterone in the human male: absence of a negative feedback effect of testosterone on follicle-stimulating hormone secretion.

Journal: The Journal of clinical endocrinology and metabolism 20010101

Title: Effect of ketoconazole 1% and 2% shampoos on severe dandruff and seborrhoeic dermatitis: clinical, squamometric and mycological assessments.

Journal: Dermatology (Basel, Switzerland) 20010101

Title: Investigation of ketoconazole copper(II) and cobalt(II) complexes and their spectrophotometric applications.

Journal: Journal of AOAC International 20010101

Title: Ketoconazole and pulmonary failure after esophagectomy: a prospective clinical trial.

Journal: Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus 20010101

Title: [Antifungal susceptibility of emerging yeast pathogens].

Journal: Enfermedades infecciosas y microbiologia clinica 20010101

Title: Systemic ketoconazole for yeast allergic patients with atopic dermatitis.

Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20010101

Title: A novel extractionless hplc fluorescence method for the determination of glyburide in the human plasma: application to a bioequivalence study.

Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20010101

Title: Guess what! Tinea capitis by Trichophyton schöenleinii.

Journal: European journal of dermatology : EJD 20010101

Title: A preliminary study on the feasibility of an automated blood-sampling system in conjunction with liquid chromatography/mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20010101

Title: Azoles for allergic bronchopulmonary aspergillosis associated with asthma.

Journal: The Cochrane database of systematic reviews 20010101

Title: Case report. Disseminated tinea of the verrucous type due to epidermophyton floccosum.

Journal: Mycoses 20010101

Title: A plea to bridge the gap between antifungals and the management of onychomycosis.

Journal: American journal of clinical dermatology 20010101

Title: [Apropos of 'Onychomycoses caused by non-dermatophytic filamentous fungi in Cádiz'].

Journal: Enfermedades infecciosas y microbiologia clinica 20010101

Title: [Antitoxic properties of hepazan--a novel inducer of microsomal enzyme system].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20010101

Title: [Acanthamoeba lesions of the cornea].

Journal: Vestnik oftalmologii 20010101

Title: Successful treatment of CAPD peritonitis caused by rhodotorula mucilaginosa.

Journal: Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20010101

Title: Lack of CYP3A4 inhibition by grapefruit juice and ketoconazole upon clozapine administration in vivo.

Journal: Drug metabolism and drug interactions 20010101

Title: [Vulvovaginal candidiasis in childhood--diagnostic and therapeutic results].

Journal: Akusherstvo i ginekologiia 20010101

Title: Recovery of bone mineral density after surgical cure, but not by ketoconazole treatment, in Cushing's syndrome.

Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20010101

Title: [Vaginal candidiasis: etiology and sensitivity profile to antifungal agents in clinical use].

Journal: Revista Argentina de microbiologia 20010101

Title: Drug susceptibility testing of Malassezia furfur strains to antifungal agents.

Journal: Folia medica 20010101

Title: [The sensitivity to ketoconazole of Candida strains isolated from the digestive tract ontocenoses in children].

Journal: Wiadomosci parazytologiczne 20010101

Title: Antiandrogenic effects of novel androgen synthesis inhibitors on hormone-dependent prostate cancer.

Journal: Cancer research 20001201

Title: Lipoproteins regulate expression of the steroidogenic acute regulatory protein (StAR) in mouse adrenocortical cells.

Journal: The Journal of biological chemistry 20001124

Title: The involvement of flavin-containing monooxygenase but not CYP3A4 in metabolism of itopride hydrochloride, a gastroprokinetic agent: comparison with cisapride and mosapride citrate.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20001001

Title: Identification of cytochrome P4503A as the major subfamily responsible for the metabolism of roquinimex in man.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20000901

Title: 3-Phenyl-5-methyl-2H,5H-furan-2-ones: tuning antifungal activity by varying substituents on the phenyl ring.

Journal: Bioorganic & medicinal chemistry letters 20000821

Title: Comparison of three different in vitro mutation assays used for the investigation of cytochrome P450-mediated mutagenicity of nitro-polycyclic aromatic hydrocarbons.

Journal: Mutation research 20000323

Title: Modulation by drugs of human hepatic sodium-dependent bile acid transporter (sodium taurocholate cotransporting polypeptide) activity.

Journal: The Journal of pharmacology and experimental therapeutics 19991201

Title: Cushing's syndrome in pregnancy treated by ketoconazole: case report and review of the literature.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 19990601

Title: In vitro susceptibilities of clinical yeast isolates to the new antifungal eberconazole compared with their susceptibilities to clotrimazole and ketoconazole.

Journal: Antimicrobial agents and chemotherapy 19990501

Title: Interplay between CYP3A-mediated metabolism and polarized efflux of terfenadine and its metabolites in intestinal epithelial Caco-2 (TC7) cell monolayers.

Journal: Pharmaceutical research 19990501

Title: Cytochrome P450 3A4 in vivo ketoconazole competitive inhibition: determination of Ki and dangers associated with high clearance drugs in general.

Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 19990101

Title: Ketoconazole reduces low dose cocaine self-administration in rats.

Journal: Drug and alcohol dependence 19981201

Title: Characterization of the cloned human intermediate-conductance Ca2+-activated K+ channel.

Journal: The American journal of physiology 19980901

Title: Synergy of nitric oxide and azoles against Candida species in vitro.

Journal: Antimicrobial agents and chemotherapy 19980901

Title: Blockade of HERG and Kv1.5 by ketoconazole.

Journal: The Journal of pharmacology and experimental therapeutics 19980801

Title: Trazodone is metabolized to m-chlorophenylpiperazine by CYP3A4 from human sources.

Journal: Drug metabolism and disposition: the biological fate of chemicals 19980601

Title: Kinetic characterization and identification of the enzymes responsible for the hepatic biotransformation of adinazolam and N-desmethyladinazolam in man.

Journal: The Journal of pharmacy and pharmacology 19980301

Title: Reduction of oxysterol levels up-regulates HMG-CoA reductase activity in rat liver.

Journal: Atherosclerosis 19970601

Title: Selective biotransformation of the human immunodeficiency virus protease inhibitor saquinavir by human small-intestinal cytochrome P4503A4: potential contribution to high first-pass metabolism.

Journal: Drug metabolism and disposition: the biological fate of chemicals 19970201

Title: Combined use of astemizole and ketoconazole resulting in torsade de pointes.

Journal: Journal of the Formosan Medical Association = Taiwan yi zhi 19970201

Title: Hepatic injury during ketoconazole therapy in patients with onychomycosis: a controlled cohort study.

Journal: Hepatology (Baltimore, Md.) 19970101

Title: In vitro synergistic activity of ketoconazole with valproic acid against Candida species.

Journal: Arzneimittel-Forschung 19960901

Title: Human reductive halothane metabolism in vitro is catalyzed by cytochrome P450 2A6 and 3A4.

Journal: Drug metabolism and disposition: the biological fate of chemicals 19960901

Title: Paranoid delusions caused by ketoconazole.

Journal: International journal of dermatology 19960101

Title: Treatment of New World cutaneous and mucosal leishmaniases.

Journal: Clinics in dermatology 19960101

Title: Antifungal agents. 9. 3-Aryl-4-[alpha-(1H-imidazol-1-yl)arylmethyl]pyrroles: a new class of potent anti-Candida agents.

Journal: Journal of medicinal chemistry 19951013

Title: In vitro susceptibility of filamentous fungi to itraconazole.

Journal: Indian journal of pathology & microbiology 19951001

Title: Synthesis and antifungal activity of new azole derivatives containing an N-acylmorpholine ring.

Journal: Journal of medicinal chemistry 19950929

Title: Mechanism for species-specific induction of Leydig cell tumors in rats by lansoprazole.

Journal: Fundamental and applied toxicology : official journal of the Society of Toxicology 19950701

Title: Novel steroidal inhibitors of human cytochrome P45017 alpha (17 alpha-hydroxylase-C17,20-lyase): potential agents for the treatment of prostatic cancer.

Journal: Journal of medicinal chemistry 19950623

Title: In vitro activity of D0870 compared with those of other azoles against fluconazole-resistant Candida spp.

Journal: Antimicrobial agents and chemotherapy 19950401

Title: Selectivity of isoprenoid-containing imidazole antifungal compounds for sterol 14-demethylase P450 (P450(14)DM) and 7-ethoxycoumarin O-deethylase P450 of rat liver microsomes.

Journal: Biochemical pharmacology 19941018

Title: Hypersensitivity to ketoconazole.

Journal: Annals of allergy 19941001

Title: Pneumocystis carinii is resistant to imidazole antifungal agents.

Journal: Antimicrobial agents and chemotherapy 19940801

Title: Derivatives of a novel cyclopeptolide. 1. Synthesis, antifungal activity, and structure-activity relationships.

Journal: Journal of medicinal chemistry 19940624

Title: Selective inhibition of mammalian lanosterol 14 alpha-demethylase by RS-21607 in vitro and in vivo.

Journal: Biochemistry 19940419

Title: Antimicrobial and antitumoral activities of 6-allyl-5,6-dihydro-5-hydroxypyran-2-one, a lactone produced by a new Drechslera species.

Journal: Die Pharmazie 19940401

Title: Ro 09-1470 is a selective inhibitor of P-450 lanosterol C-14 demethylase of fungi.

Journal: Antimicrobial agents and chemotherapy 19931201

Title: Effects of the combination of ketoconazole and calmodulin inhibitors against Candida albicans in vitro. Short communication.

Journal: Arzneimittel-Forschung 19930901

Title: Antifungal agents. VI. In vitro antifungal activities of halobenzoyl esters of cis- and trans-[2-(1,1'-biphenyl-4-yl)-2-(1H-imidazol-1-ylmethyl)-1,3- dioxolan-4-yl]carbinols.

Journal: Farmaco (Societa chimica italiana : 1989) 19930801

Title: Synthesis and structure-activity relationships of phenyl-substituted benzylamine antimycotics: a novel benzylbenzylamine antifungal agent for systemic treatment.

Journal: Journal of medicinal chemistry 19930723

Title: Selective inhibition of mammalian lanosterol 14 alpha-demethylase: a possible strategy for cholesterol lowering.

Journal: Journal of medicinal chemistry 19930723

Title: Effects of the combination of ketoconazole and calcium channel antagonists against Candida albicans in vitro.

Journal: Arzneimittel-Forschung 19930701

Title: Ventricular fibrillation secondary to itraconazole induced hypokalaemia.

Journal: The Journal of infection 19930501

Title: Ketoconazole induced papilledema.

Journal: Acta ophthalmologica 19930401

Title: Torsades de pointes after terfenadine-itraconazole interaction.

Journal: BMJ (Clinical research ed.) 19930116

Title: Erythromycin and ketoconazole (Nizoral) associated with terfenadine (Seldane)-induced ventricular arrhythmias.

Journal: General dentistry 19930101

Title: Evidence for CYP3A-mediated N-deethylation of amiodarone in human liver microsomal fractions.

Journal: Drug metabolism and disposition: the biological fate of chemicals 19930101

Title: [Treatment with terfenadine and ketoconazole or itraconazole can cause torsades de pointes ventricular tachycardia].

Journal: Duodecim; laaketieteellinen aikakauskirja 19930101

Title: Drug-induced gynecomastia.

Journal: Pharmacotherapy 19930101

Title: Antifungal activity of meridine, a natural product from the marine sponge Corticium sp.

Journal: Journal of natural products 19921101

Title: Antibacterial and antifungal agents. XV. Synthesis and antifungal activity of structural analogues of bifonazole and ketoconazole.

Journal: Archiv der Pharmazie 19921101

Title: Stereoisomers of ketoconazole: preparation and biological activity.

Journal: Journal of medicinal chemistry 19920724

Title: Reduction of chromium(VI) to chromium(V) by rat liver cytosolic and microsomal fractions: is DT-diaphorase involved?

Journal: Carcinogenesis 19920701

Title: Torsades de Pointes after treatment with terfenadine and ketoconazole.

Journal: European heart journal 19920701

Title: Comparative study of six antifungal treatments in an experimental model of murine cryptococcosis.

Journal: European journal of epidemiology 19920501

Title: Uroporphyrinogen oxidation catalyzed by reconstituted cytochrome P450IA2.

Journal: Archives of biochemistry and biophysics 19920501

Title: In vitro activity of cloconazole, sulconazole, butoconazole, isoconazole, fenticonazole, and five other antifungal agents against clinical isolates of Candida albicans and Candida spp.

Journal: Mycopathologia 19920401

Title: The mechanism of bioactivation and antigen formation of amodiaquine in the rat.

Journal: Biochemical pharmacology 19920401

Title: Placebo-controlled clinical trial of sodium stibogluconate (Pentostam) versus ketoconazole for treating cutaneous leishmaniasis in Guatemala.

Journal: The Journal of infectious diseases 19920301

Title: Acute renal failure after liver transplantation in patients treated with cyclosporine.

Journal: Transplantation proceedings 19920201

Title: Ketoconazole and high-dose methylprednisolone predisposing to cyclosporine-induced seizures: report of 3 cases.

Journal: Acta haematologica 19920101

Title: Synthesis, specificity, and antifungal activity of inhibitors of the Candida albicans delta 24-sterol methyltransferase.

Journal: Journal of medicinal chemistry 19920101

Title: Myopathy associated with ketoconazole treatment.

Journal: American journal of diseases of children (1960) 19910901

Title: Ketoconazole-induced fulminant hepatitis necessitating liver transplantation.

Journal: Journal of the American Academy of Dermatology 19910801

Title: Drug induced suicidal ideation.

Journal: The Israel journal of psychiatry and related sciences 19910101

Title: Torsades de pointes occurring in association with terfenadine use.

Journal: JAMA 19901205

Title: Effects of pentamidine alone and in combination with ketoconazole or itraconazole on the growth of Candida albicans.

Journal: Antimicrobial agents and chemotherapy 19901201

Title: Massive hepatic enlargement with fatty change associated with ketoconazole.

Journal: DICP : the annals of pharmacotherapy 19901201

Title: Cyclosporine and itraconazole interaction in heart and lung transplant recipients.

Journal: Annals of internal medicine 19900815

Title: Efficacy of ketoconazole against Leishmania braziliensis panamensis cutaneous leishmaniasis.

Journal: The American journal of medicine 19900801

Title: Arterial hypertension as a complication of prolonged ketoconazole treatment.

Journal: Journal of hypertension. Supplement : official journal of the International Society of Hypertension 19891201

Title: Adverse psychiatric reaction to ketoconazole.

Journal: The American journal of psychiatry 19890701

Title: Neurologic complications of ketoconazole therapy for advanced prostatic cancer.

Journal: Urology 19890601

Title: [Toxic hepatitis caused by ketoconazole: a report of 4 cases].

Journal: Revista paulista de medicina 19890101

Title: Studies on antifungal agents. 23. Novel substituted 3,5-diphenyl-3-(1H-imidazol-1-ylmethyl)- 2-alkylisoxazolidine derivatives.

Journal: Journal of medicinal chemistry 19881001

Title: In-vivo effects of itraconazole on hepatic mixed-function oxidase.

Journal: The Journal of antimicrobial chemotherapy 19880201

Title: Prolonged jaundice following ketoconazole-induced hepatic injury.

Journal: Digestive diseases and sciences 19880201

Title: [Cholestatic hepatitis caused by ketoconazole].

Journal: Annales de gastroenterologie et d'hepatologie 19880101

Title: Itraconazole and cyclosporin nephrotoxicity.

Journal: Lancet (London, England) 19871017

Title: Hypertension during high-dose ketoconazole treatment: a probable mineralocorticosteroid effect.

Journal: Lancet (London, England) 19870912

Title: Antifungal activity of the allylamine derivative terbinafine in vitro.

Journal: Antimicrobial agents and chemotherapy 19870901

Title: Lysosomotropic agents. 7. Broad-spectrum antifungal activity of lysosomotropic detergents.

Journal: Journal of medicinal chemistry 19870801

Title: Synthesis and oral antifungal activity of novel azolylpropanolones and related compounds.

Journal: Journal of medicinal chemistry 19870601

Title: Immune hemolytic anemia associated with ketoconazole therapy.

Journal: Clinical pharmacy 19870601

Title: Hepatic reactions associated with ketoconazole in the United Kingdom.

Journal: British medical journal (Clinical research ed.) 19870214

Title: Ketoconazole-induced hepatitis: a case with a definite cause-effect relationship.

Journal: Liver 19870201

Title: [Hepatic lesions induced by drugs. Report of 26 cases].

Journal: Acta gastroenterologica Latinoamericana 19870101

Title: Activity of SM-4470, a new imidazole derivative, against experimental fungal infections.

Journal: Antimicrobial agents and chemotherapy 19860901

Title: In vitro activity of ketoconazole against herpes simplex virus.

Journal: Antimicrobial agents and chemotherapy 19860801

Title: Ketoconazole-associated hepatic injury. A clinicopathological study of 55 cases.

Journal: Journal of hepatology 19860101

Title: Experimental cyclosporine nephrotoxicity: risk of concomitant chemotherapy.

Journal: Clinical nephrology 19860101

Title: Ketoconazole-induced fulminant hepatitis.

Journal: Gut 19850601

Title: Activity of UK-49,858, a bis-triazole derivative, against experimental infections with Candida albicans and Trichophyton mentagrophytes.

Journal: Antimicrobial agents and chemotherapy 19850501

Title: Treatment of canine blastomycosis with amphotericin B and ketoconazole.

Journal: Journal of the American Veterinary Medical Association 19840515

Title: Hepatic injury associated with ketoconazole therapy. Analysis of 33 cases.

Journal: Gastroenterology 19840301

Title: Toxic hepatitis following ketoconazole treatment.

Journal: Scandinavian journal of infectious diseases 19840101

Title: [Ketoconazole-induced hepatitis. Case report].

Journal: Zeitschrift fur Gastroenterologie 19831201

Title: [Toxic hepatitis caused by ketoconazole].

Journal: Nederlands tijdschrift voor geneeskunde 19830618

Title: Synthesis of (E)-1-(5-chlorothien-2-yl)-2-(1H-imidazol-1-yl)ethanone 2,6-dichlorophenylhydrazone hydrochloride, a novel, orally active antifungal agent.

Journal: Journal of medicinal chemistry 19830301

Title: [Toxic hepatitis caused by ketoconazole (Nizoral)].

Journal: Nederlands tijdschrift voor geneeskunde 19830219

Title: 3',5'-cyclic adenosine monophosphate response element binding protein up-regulated cytochrome P450 lanosterol 14alpha-demethylase expression involved in follicle-stimulating hormone-induced mouse oocyte maturation.

Journal: Molecular endocrinology (Baltimore, Md.)

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SDS
Tags:142128-57-2 Molecular Formula|142128-57-2 MDL|142128-57-2 SMILES|142128-57-2 1-(4-(4-(((2S,4R)-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)ethanone