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10040-45-6,MFCD28009648
Catalog No.:AA0001V0

10040-45-6 | Phenol, 4,4'-(2-pyridinylmethylene)bis-, 1,1'-bis(hydrogen sulfate), sodium salt (1:2)

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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0001V0
Chemical Name:
Phenol, 4,4'-(2-pyridinylmethylene)bis-, 1,1'-bis(hydrogen sulfate), sodium salt (1:2)
CAS Number:
10040-45-6
Molecular Formula:
C18H13NNa2O8S2
Molecular Weight:
481.4073
MDL Number:
MFCD28009648
SMILES:
[O-]S(=O)(=O)Oc1ccc(cc1)C(c1ccccn1)c1ccc(cc1)OS(=O)(=O)[O-].[Na+].[Na+]
Properties
Computed Properties
 
Complexity:
633  
Covalently-Bonded Unit Count:
3  
Heavy Atom Count:
31  
Hydrogen Bond Acceptor Count:
9  
Rotatable Bond Count:
5  

Literature

Title: Comparison of patient acceptance of sodium phosphate versus polyethylene glycol plus sodium picosulfate for colon cleansing in Japanese.

Journal: Journal of gastroenterology and hepatology 20121001

Title: A pilot study on the efficacy of Picolax given as a four-week course for the treatment of refractory constipation.

Journal: Hong Kong medical journal = Xianggang yi xue za zhi 20121001

Title: Laxative-free CT colonography.

Journal: The British journal of radiology 20120801

Title: Serial monitoring of the physiological effects of the standard Pico-Salax® regimen for colon cleansing in healthy volunteers.

Journal: Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20120701

Title: Split-dose picosulfate, magnesium oxide, and citric acid solution markedly enhances colon cleansing before colonoscopy: a randomized, controlled trial.

Journal: Gastrointestinal endoscopy 20120301

Title: Laxative management in ambulatory cancer patients on opioid therapy: a prospective, open-label investigation of polyethylene glycol, sodium picosulphate and lactulose.

Journal: European journal of cancer care 20120101

Title: Same-day bowel cleansing regimen is superior to a split-dose regimen over 2 days for afternoon colonoscopy: results from a large prospective series.

Journal: Journal of clinical gastroenterology 20120101

Title: Same day prep for afternoon colonoscopy: everybody wins!

Journal: Journal of clinical gastroenterology 20120101

Title: Budget-impact model for colonoscopy cost calculation and comparison between 2 litre PEG+ASC and sodium picosulphate with magnesium citrate or sodium phosphate oral bowel cleansing agents.

Journal: Journal of medical economics 20120101

Title: Drug eruption due to sodium picosulfate.

Journal: European journal of dermatology : EJD 20120101

Title: Service implications of implementing guidance for oral bowel cleansing agents in colonoscopy.

Journal: The journal of the Royal College of Physicians of Edinburgh 20110601

Title: Bowel cleansing for colonoscopy: prospective randomized assessment of efficacy and of induced mucosal abnormality with three preparation agents.

Journal: Endoscopy 20110501

Title: Absence of excretion of the active moiety of bisacodyl and sodium picosulfate into human breast milk: an open-label, parallel-group, multiple-dose study in healthy lactating women.

Journal: Drug metabolism and pharmacokinetics 20110101

Title: Bowel preparation regimen for computed tomography colonography.

Journal: Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes 20101201

Title: Evidence-based recommendations for bowel cleansing before colonoscopy in children: a report from a national working group.

Journal: Endoscopy 20101201

Title: Multicenter, 4-week, double-blind, randomized, placebo-controlled trial of sodium picosulfate in patients with chronic constipation.

Journal: The American journal of gastroenterology 20100401

Title: A possible troponin I leak arising from bowel preparation for elective colonoscopy - are there more implications than observed?

Journal: Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland 20100301

Title: Pico-Salax versus polyethylene glycol for bowel cleanout before colonoscopy in children: a randomized controlled trial.

Journal: Endoscopy 20091201

Title: A multicentre, observational study of sodium picosulfate and magnesium citrate as a precolonoscopy bowel preparation.

Journal: Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20091001

Title: [Preparation of colonoscopy: well tolerable combination preparation admitted in Germany].

Journal: MMW Fortschritte der Medizin 20090924

Title: Plasma magnesium should be monitored perioperatively in patients undergoing colorectal resection.

Journal: Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland 20090701

Title: The rapid development of hyponatraemia and seizures in an elderly patient following sodium picosulfate/magnesium citrate (Picolax).

Journal: Age and ageing 20090701

Title: Pico-salax plus two-day bisacodyl is superior to pico-salax alone or oral sodium phosphate for colon cleansing before colonoscopy.

Journal: The American journal of gastroenterology 20090301

Title: Sodium picosulfate/magnesium citrate: a review of its use as a colorectal cleanser.

Journal: Drugs 20090101

Title: [Optimization of perioperative management in laparoscopic hernioplasty].

Journal: Der Anaesthesist 20080901

Title: A randomized controlled trial comparing the efficacy and acceptability of phospo-soda buffered saline (Fleet) with sodium picosulphate/magnesium citrate (Picoprep) in the preparation of patients for colonoscopy.

Journal: Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland 20080601

Title: A randomised controlled trial of a new 2 litre polyethylene glycol solution versus sodium picosulphate + magnesium citrate solution for bowel cleansing prior to colonoscopy.

Journal: Current medical research and opinion 20080201

Title: OTC laxative use of sodium picosulfate â results of a pharmacy-based patient survey (cohort study).

Journal: International journal of clinical pharmacology and therapeutics 20080201

Title: [Treatment with bisacodyl, picosulfate and prokinetics. Physiopathology and diagnosis of constipation].

Journal: Pharmazie in unserer Zeit 20080101

Title: Factors affecting outcomes in colonoscopy.

Journal: Gastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates 20080101

Title: Comparison of colon-cleansing methods in preparation for colonoscopy--comparative efficacy of solutions of mannitol, sodium picosulfate and monobasic and dibasic sodium phosphates.

Journal: Acta cirurgica brasileira 20080101

Title: Commonly used bowel preparations have significant and different effects upon cell proliferation in the colon: a pilot study.

Journal: BMC gastroenterology 20080101

Title: Interaction between Shaoyao-Gancao-Tang and a laxative with respect to alteration of paeoniflorin metabolism by intestinal bacteria in rats.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20070801

Title: Is patient outcome affected by the administration of intravenous fluid during bowel preparation for colonic surgery?

Journal: Annals of the Royal College of Surgeons of England 20070701

Title: Randomised, placebo-controlled, double-blind study to investigate the efficacy and safety of the acute use of sodium picosulphate in patients with chronic constipation.

Journal: International journal of clinical practice 20070601

Title: Comparison of bisacodyl and sodium picosulphate in the treatment of chronic constipation.

Journal: Current medical research and opinion 20070401

Title: A review of current issues underlying colon cleansing before colonoscopy.

Journal: Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20070201

Title: Randomized clinical trial comparing sodium picosulfate with mannitol on the preparation FOR colonoscopy in hospitalized patients.

Journal: Arquivos de gastroenterologia 20070101

Title: [Preparation for colonoscopy using 1,000 ml Magcorol P isotonic solution in the absence of dietary restrictions or use of purgatives on the preceding day].

Journal: Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru 20070101

Title: Sodium picosulfate in opioid-induced constipation: results of an open-label, prospective, dose-ranging study.

Journal: Palliative medicine 20060601

Title: Which is the optimal bowel preparation for colonoscopy - a meta-analysis.

Journal: Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland 20060501

Title: Audit of bowel preparation with Picolax (sodium picosulfate plus magnesium citrate) for colonoscopy.

Journal: International journal of clinical practice 20060501

Title: An unusual difficulty in bowel preparation for emergency colonoscopy.

Journal: Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland 20060101

Title: Bioavailability of glycyrrhizin from Shaoyao-Gancao-Tang in laxative-treated rats.

Journal: The Journal of pharmacy and pharmacology 20051001

Title: Effects of oral sodium picosulphate Picolax on urea and electrolytes.

Journal: Nursing standard (Royal College of Nursing (Great Britain) : 1987) 20050701

Title: Screening procedure for detection of stimulant laxatives and/or their metabolites in human urine using gas chromatography-mass spectrometry after enzymatic cleavage of conjugates and extractive methylation.

Journal: Therapeutic drug monitoring 20050401

Title: Randomized single blind trial of two low-volume bowel preparations for screening computed tomographic colonography.

Journal: Abdominal imaging 20050101

Title: Psychological well-being and symptoms in women with chronic constipation treated with sodium picosulphate.

Journal: Gastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates 20050101

Title: Retrospective study of long-term treatment with sodium picosulfate.

Journal: European journal of gastroenterology & hepatology 20040401

Title: Picoprep-3 is a superior colonoscopy preparation to Fleet: a randomized, controlled trial comparing the two bowel preparations.

Journal: Diseases of the colon and rectum 20040201

Title: [Bowel preparation for colonoscopy with sodium picosulphate and magnesium citrate in children and adolescents].

Journal: Arquivos de gastroenterologia 20040101

Title: Optimizing bowel preparation for multidetector row CT colonography: effect of Citramag and Picolax.

Journal: Clinical radiology 20030901

Title: [Comparison of the effectiveness and tolerability of the saccharosum-sennosid-B solution and sodium-picosulfate in preparation for colonoscopy. Prospective, multicenter, randomized study].

Journal: Orvosi hetilap 20030810

Title: Randomized clinical trial of intravenous fluid replacement during bowel preparation for surgery.

Journal: The British journal of surgery 20011001

Title: Investigation of the effects of YM-31636, a novel 5-HT3 receptor agonist, on defecation in normal and constipated ferrets.

Journal: European journal of pharmacology 20010720

Title: Analytical control of a pharmaceutical formulation of sodium picosulfate by capillary zone electrophoresis.

Journal: Journal of chromatography. B, Biomedical sciences and applications 20010210

Title: The role of intestinal bacteria in the transformation of sodium picosulfate.

Journal: Japanese journal of pharmacology 19920501

Title: Toxicity study with sodium picosulfate in cultured liver cells of rabbit, rat and man.

Journal: Arzneimittel-Forschung 19810101

Title: Nishikawa, J. and A. Kast, Toxicity study with sodium picosulfate in cultured liver cells of rabbit, rat and man. Arzneimittelforschung, 1981. 31(2): p. 321-5.

Title: Geboes, K., et al., Effects of 'contact laxatives' on intestinal and colonic epithelial cell proliferation. Pharmacology, 1993. 47 Suppl 1: p. 187-95.

Title: Fioramonti, J., C. Dupuy, and L. Bueno, In vivo motility of rat colon chronically pretreated with sennosides. Pharmacology, 1993. 47 Suppl 1: p. 155-61.

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Tags:10040-45-6 Molecular Formula|10040-45-6 MDL|10040-45-6 SMILES|10040-45-6 Phenol, 4,4'-(2-pyridinylmethylene)bis-, 1,1'-bis(hydrogen sulfate), sodium salt (1:2)