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100491-29-0,MFCD01863285
Catalog No.:AA00H95R

100491-29-0 | Ethyl 7-chloro-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate

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Purity
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1g
97%
in stock  
$7.00   $5.00
- +
5g
97%
in stock  
$9.00   $7.00
- +
100g
97%
in stock  
$123.00   $86.00
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00H95R
Chemical Name:
Ethyl 7-chloro-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate
CAS Number:
100491-29-0
Molecular Formula:
C17H10ClF3N2O3
Molecular Weight:
382.7211
MDL Number:
MFCD01863285
SMILES:
CCOC(=O)c1cn(c2ccc(cc2F)F)c2c(c1=O)cc(c(n2)Cl)F
Properties
Computed Properties
 
Complexity:
606  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
8  
Rotatable Bond Count:
4  
XLogP3:
4  

Upstream Synthesis Route

[1]Patent:US4704459,1987,A,

[1]JournalofMedicinalChemistry,1986,vol.29,#11,p.2364-2369

[2]JournalofMedicinalChemistry,1992,vol.35,#3,p.518-525

[3]Patent:US2014/73631,2014,A1,.Locationinpatent:Paragraph0128;0133

[1]JournalofMedicinalChemistry,1986,vol.29,#11,p.2364-2369

[2]JournalofMedicinalChemistry,1992,vol.35,#3,p.518-525

[3]Patent:US2014/73631,2014,A1,

[1]JournalofMedicinalChemistry,1986,vol.29,#11,p.2364-2369

[2]JournalofMedicinalChemistry,1992,vol.35,#3,p.518-525

[3]Patent:US2014/73631,2014,A1,

[1]JournalofMedicinalChemistry,1986,vol.29,#11,p.2364-2369

[2]JournalofMedicinalChemistry,1992,vol.35,#3,p.518-525

[3]Patent:US2014/73631,2014,A1,

Downstream Synthesis Route

[1]JournalofMedicinalChemistry,1986,vol.29,p.2364-2369

[2]Patent:WO2005/70940,2005,A2.Locationinpatent:Page/Pagecolumn38

[1]JournalofMedicinalChemistry,1986,vol.29,p.2364-2369

116183-84-7    100491-29-0   
7-(1R,4R)-2,5-Diaza-bicyclo2.2.1hept-2-yl-1-(2,4-difluoro-phenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8naphthyridine-3-carboxylicacidethylester 

[1]JournalofMedicinalChemistry,1992,vol.35,p.518-525

132339-20-9    100491-29-0   
7-(1S,4S)-2,5-Diaza-bicyclo2.2.1hept-2-yl-1-(2,4-difluoro-phenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8naphthyridine-3-carboxylicacidethylester 

[1]JournalofMedicinalChemistry,1988,vol.31,p.1598-1611

[1]JournalofMedicinalChemistry,1986,vol.29,p.2364-2369

Literature
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