Title: N-Methyl-2-pyridone-5-carboxamide is 1-methylnicotinamide metabolite of low cyclooxygenase-dependent vasodilating activity.
Journal: Journal of physiology and biochemistry 20120901
Title: Simultaneous quantification of niacin and its three main metabolites in human plasma by LC-MS/MS.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120901
Title: Effects of 1-methylnicotinamide and its metabolite N-methyl-2-pyridone-5-carboxamide on streptozotocin-induced toxicity in murine insulinoma MIN6 cell line.
Journal: Acta biochimica Polonica 20110101
Title: Simultaneous determination of niacin and its metabolites--nicotinamide, nicotinuric acid and N-methyl-2-pyridone-5-carboxamide--in human plasma by LC-MS/MS and its application to a human pharmacokinetic study.
Journal: Biomedical chromatography : BMC 20101001
Title: Distribution of purine nucleotides in uremic fluids and tissues.
Journal: Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20100901
Title: Urinary metabolic phenotyping differentiates children with autism from their unaffected siblings and age-matched controls.
Journal: Journal of proteome research 20100604
Title: Metabonomics study of urine and plasma in depression and excess fatigue rats by ultra fast liquid chromatography coupled with ion trap-time of flight mass spectrometry.
Journal: Molecular bioSystems 20100501
Title: Development of a hydrophilic liquid interaction chromatography-high-performance liquid chromatography-tandem mass spectrometry based stable isotope dilution analysis and pharmacokinetic studies on bioactive pyridines in human plasma and urine after coffee consumption.
Journal: Analytical chemistry 20100215
Title: Are so-called uremic toxins always toxic?
Journal: Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20080101
Title: Nicotinamide metabolites accumulate in the tissues of uremic rats.
Journal: Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20080101
Title: The comparative bioavailability of an extended-release niacin and lovastatin fixed dose combination tablet versus extended-release niacin tablet, lovastatin tablet and a combination of extended-release niacin tablet and lovastatin tablet.
Journal: Biopharmaceutics & drug disposition 20070901
Title: Plasma and urine pharmacokinetics of niacin and its metabolites from an extended-release niacin formulation.
Journal: International journal of clinical pharmacology and therapeutics 20070801
Title: Effect of the rate of niacin administration on the plasma and urine pharmacokinetics of niacin and its metabolites.
Journal: Journal of clinical pharmacology 20070601
Title: A metabolomic comparison of urinary changes in type 2 diabetes in mouse, rat, and human.
Journal: Physiological genomics 20070424
Title: Relationship between uremic toxins and oxidative stress in patients with chronic renal failure.
Journal: Scandinavian journal of urology and nephrology 20070101
Title: Accumulation of poly(ADP-ribose) polymerase inhibitors in children with chronic renal failure.
Journal: Pediatric nephrology (Berlin, Germany) 20060601
Title: Estimation of aldehyde oxidase activity in vivo from conversion ratio of N1-methylnicotinamide to pyridones, and intraspecies variation of the enzyme activity in rats.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20060201
Title: The novel nucleotide 4KNTP, in high concentrations in erythrocytes of renal failure children: a comparison with accumulation of other putative precursors in the plasma.
Journal: Nucleosides, nucleotides & nucleic acids 20060101
Title: The effect of N-methyl-2-pyridone-5-carboxamide--A nicotinamide catabolite on poly ADP-rybosylation and oxidative stress injury in endothelial cells.
Journal: Nucleosides, nucleotides & nucleic acids 20050101
Title: The age-related increase in N-methyl-2-pyridone-5-carboxamide (NAD catabolite) in human plasma.
Journal: Molecular and cellular biochemistry 20041201
Title: An unusual pyridine nucleotide accumulating in erythrocytes: its identity and positive correlation with degree of renal failure.
Journal: Nucleosides, nucleotides & nucleic acids 20041001
Title: Disturbances of purine nucleotide metabolism in uremia.
Journal: Seminars in nephrology 20040901
Title: Origin and characteristics of an unusual pyridine nucleotide accumulating in erythrocytes: positive correlation with degree of renal failure.
Journal: Clinica chimica acta; international journal of clinical chemistry 20030901
Title: N-methyl-2-pyridone-5-carboxamide: a novel uremic toxin?
Journal: Kidney international. Supplement 20030501
Title: Accumulation of plasma N-methyl-2-pyridone-5-carboxamide in patients with chronic renal failure.
Journal: Molecular and cellular biochemistry 20020201
Title: The metabolism of nicotinamide in human liver cirrhosis: a study on N-methylnicotinamide and 2-pyridone-5-carboxamide production.
Journal: The American journal of gastroenterology 20010401