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Home Other Building Blocks 1009816-48-1
1009816-48-1,MFCD15144964
Catalog No.:AA00039U

1009816-48-1 | Thiamet g

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$36.00   $25.00
- +
5mg
98%
in stock  
$89.00   $62.00
- +
10mg
98%
in stock  
$133.00   $93.00
- +
100mg
95%
in stock  
$594.00   $416.00
- +
250mg
95%
in stock  
$843.00   $590.00
- +
1g
95%
in stock  
$2,389.00   $1,673.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00039U
Chemical Name:
Thiamet g
CAS Number:
1009816-48-1
Molecular Formula:
C9H16N2O4S
Molecular Weight:
248.2993
MDL Number:
MFCD15144964
SMILES:
CCNC1=N[C@H]2[C@@H](S1)O[C@@H]([C@H]([C@@H]2O)O)CO
Properties
Computed Properties
 
Complexity:
289  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
2  
Undefined Atom Stereocenter Count:
5  
XLogP3:
-0.7  

Downstream Synthesis Route

[1]CurrentPatentAssignee:ALECTOSTHERAPEUTICSINC;MERCK&COINC-WO2012/64680,2012,A1Locationinpatent:Page/Pagecolumn138

[2]CurrentPatentAssignee:ALECTOSTHERAPEUTICSINC;MERCK&COINC-WO2012/62157,2012,A1Locationinpatent:Page/Pagecolumn138;139

[1]CurrentPatentAssignee:ALECTOSTHERAPEUTICSINC;MERCK&COINC-WO2012/64680,2012,A1

[2]CurrentPatentAssignee:ALECTOSTHERAPEUTICSINC;MERCK&COINC-WO2012/62157,2012,A1

[1]CurrentPatentAssignee:ALECTOSTHERAPEUTICSINC;MERCK&COINC-WO2012/64680,2012,A1

[2]CurrentPatentAssignee:ALECTOSTHERAPEUTICSINC;MERCK&COINC-WO2012/62157,2012,A1

[1]CurrentPatentAssignee:ALECTOSTHERAPEUTICSINC;MERCK&COINC-WO2012/64680,2012,A1

[2]CurrentPatentAssignee:ALECTOSTHERAPEUTICSINC;MERCK&COINC-WO2012/62157,2012,A1

[1]CurrentPatentAssignee:ALECTOSTHERAPEUTICSINC;MERCK&COINC-WO2012/64680,2012,A1

[2]CurrentPatentAssignee:ALECTOSTHERAPEUTICSINC;MERCK&COINC-WO2012/62157,2012,A1

Literature

Title: Modulation of O-GlcNAc Levels in the Liver Impacts Acetaminophen-Induced Liver Injury by Affecting Protein Adduct Formation and Glutathione Synthesis.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20180401

Title: O-Linked N-Acetylglucosamine (O-GlcNAc) Transferase and O-GlcNAcase Interact with Mi2β Protein at the Aγ-Globin Promoter.

Journal: The Journal of biological chemistry 20160722

Title: O-GlcNAc transferase inhibits KSHV propagation and modifies replication relevant viral proteins as detected by systematic O-GlcNAcylation analysis.

Journal: Glycobiology 20131001

Title: Yuzwa SA, et al. Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation. Nat Chem Biol. 2012 Feb 26;8(4):393-9.

Title: Andrés-Bergós J, et al. The increase in O-linked N-acetylglucosamine protein modification stimulates chondrogenic differentiation both in vitro and in vivo. J Biol Chem. 2012 Sep 28;287(40):33615-28.

Title: Ding N, et al. Thiamet-G-mediated inhibition of O-GlcNAcase sensitizes human leukemia cells to microtubule-stabilizing agent NSC 125973. Biochem Biophys Res Commun. 2014 Oct 24;453(3):392-7.

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SDS
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Tags:1009816-48-1 Molecular Formula|1009816-48-1 MDL|1009816-48-1 SMILES|1009816-48-1 Thiamet g