Home Other Building Blocks 100986-86-5
100986-86-5,MFCD00869643
Catalog No.:AA0003AX

100986-86-5 | (R)-Ofloxacin

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$98.00   $68.00
- +
5mg
≥98%
in stock  
$288.00   $201.00
- +
10mg
≥98%
in stock  
$479.00   $335.00
- +
100mg
95%
in stock  
$730.00   $511.00
- +
500mg
95%
in stock  
$2,089.00   $1,462.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0003AX
Chemical Name:
(R)-Ofloxacin
CAS Number:
100986-86-5
Molecular Formula:
C18H20FN3O4
Molecular Weight:
361.3675
MDL Number:
MFCD00869643
SMILES:
CN1CCN(CC1)c1c(F)cc2c3c1OC[C@H](n3cc(c2=O)C(=O)O)C
Properties
Computed Properties
 
Complexity:
634  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
XLogP3:
-0.4  

Downstream Synthesis Route
109-01-3   
(+)-9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido<1,2,3-de><1,4>benzoxazine-6-carboxylicacidBF2-chelate 
  100986-86-5 

[1]Atarashi;Yokohama;Yamazaki;Sakano;Imamura;Hayakawa[Chemicalandpharmaceuticalbulletin,1987,vol.35,#5,p.1896-1902]

[1]CurrentPatentAssignee:BAINCAPITALINC-EP368410,1990,A3

[2]Mitscher;Sharma;Chu;Shen;Pernet[JournalofMedicinalChemistry,1987,vol.30,#12,p.2283-2286]

[3]Adrio,Javier;Carretero,JuanC.;GarciaRuano,JoseL.;Pallares,Antonio;Vicioso,Mercedes[Heterocycles,1999,vol.51,#7,p.1563-1572]

[4]Locationinpatent:experimentalpartRueping,Magnus;Stoeckel,Mirjam;Sugiono,Erli;Theissmann,Thomas[Tetrahedron,2010,vol.66,#33,p.6565-6568]

[1]Chirality,2012,vol.24,p.661-667

[2]JournaloftheChineseChemicalSociety,2007,vol.54,p.991-995

[3]JournaloftheChileanChemicalSociety,2011,vol.56,p.642-645

[4]Chirality,2013,vol.25,p.409-414

[5]JournalofInclusionPhenomenaandMacrocyclicChemistry,2013,vol.77,p.291-300

[6]Chirality,2015,vol.27,p.306-313

[7]Patent:CN103664998,2016,B.Locationinpatent:Paragraph0020;0021

[8]Chirality,2018,vol.30,p.828-836

[9]Chirality,2018,vol.30,p.1304-1311

[10]ChineseChemicalLetters,2019,vol.30,p.643-649

[1]Heterocycles,1999,vol.51,p.1563-1572

[1]Adrio,Javier;Carretero,JuanC.;GarciaRuano,JoseL.;Pallares,Antonio;Vicioso,Mercedes[Heterocycles,1999,vol.51,#7,p.1563-1572]

Literature

Title: Spectrum of activity of levofloxacin against nontuberculous mycobacteria and its activity against the Mycobacterium avium complex in combination with ethambutol, rifampin, roxithromycin, amikacin, and clofazimine.

Journal: Antimicrobial agents and chemotherapy 19961101

Title: In vitro activities of levofloxacin used alone and in combination with first- and second-line antituberculous drugs against Mycobacterium tuberculosis.

Journal: Antimicrobial agents and chemotherapy 19960701

Title: Fluoroquinolones protect the human lymphocyte CEM cell line from HIV-1-mediated cytotoxicity.

Journal: Cell structure and function 19901001

Title: Nahla N. Salama, et al. Thin-Layer Chromatographic Enantioseparation of Ofloxacin and Zopiclone using Hydroxy-Propyl-BetaCyclodextrin as Chiral Selector and Thermodynamic Studies of Complexation. Journal of Planar Chromatography. 27 (2014) 3, 166-173.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:100986-86-5 Molecular Formula|100986-86-5 MDL|100986-86-5 SMILES|100986-86-5 (R)-Ofloxacin