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10102-17-7,MFCD00003499
Catalog No.:AA0003HE
10102-17-7 | Sodium thiosulfate pentahydrate
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Purity
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25g
95%
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$28.00   $20.00
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100g
99%
in stock  
$65.00   $45.00
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500g
99%
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$108.00   $75.00
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Technical Information
Catalog Number:
AA0003HE
Chemical Name:
Sodium thiosulfate pentahydrate
CAS Number:
10102-17-7
Molecular Formula:
H10Na2O8S2
Molecular Weight:
248.1841
MDL Number:
MFCD00003499
IUPAC Name:
disodium;dioxido-oxo-sulfanylidene-λ6-sulfane;pentahydrate
InChI:
InChI=1S/2Na.H2O3S2.5H2O/c;;1-5(2,3)4;;;;;/h;;(H2,1,2,3,4);5*1H2/q2*+1;;;;;;/p-2
InChI Key:
PODWXQQNRWNDGD-UHFFFAOYSA-L
SMILES:
[O-]S(=S)(=O)[O-].O.O.O.O.O.[Na+].[Na+]
EC Number:
600-156-5
UNII:
HX1032V43M
Properties
Computed Properties
 
Complexity:
82.6  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
8  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
247.961g/mol
Formal Charge:
0
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
5  
Isotope Atom Count:
0
Molecular Weight:
248.172g/mol
Monoisotopic Mass:
247.961g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
109A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0

Synonyms
 
pentahydrate of sodium thiosulfate 
sodium thiosulfate 
Disodium thiosulfate pentahydrate 
MFCD00149186 
Antichlor 
Tinver 
UNII-HX1032V43M 
CCRIS 3952 
Thiosulfuric acid, disodium salt, pentahydrate 
NSC-45624 
Sodium Hyposulfite Pentahydrate 
Thiosulfuric acid (H2S2O3), disodium salt, pentahydrate 
sodium thiosulfate (USAN) 
CHEBI:32150 
HX1032V43M 
AK120935 
Sodium Thiosulfate Pentahydrate Solution 
Sodium thiosulfate pentahydrate, 99+%, extra pure 
Sodium thiosulfate pentahydrate, 99.5%, for analysis 
Sodium thiosulfate pentahydrate, 99+%, for biochemistry 
Na2S2O3.5H2O 
Sodium thiosulfate pentahydrate, 99.999%, (trace metal basis) 
Sodium thiosulfate [USP:JAN] 
sodium thiosulfate anhydrous 
Sodium thiosulfate [USAN:JAN] 
Sulfactol (TN) 
Detoxol (TN) 
PEDMARK 
ACMC-20ajnc 
Sodium thiosulfate (USP) 
Sodium thiosulphate hydrate 
Sodiumthiosulfatepentahydrate 
AC1L1VB2 
KSC175I8H 
sodium thiosulfate pentahydrate 
sodium thiosulfate-pentahydrate 
SODIUM THIOSULFATE, ACS 
sodium thio-sulfate pentahydrate 
CHEMBL2096650 
DTXSID6044197 
CTK0H5483 
KS-00000UDU 
PODWXQQNRWNDGD-UHFFFAOYSA-L 
Sodium thiosulfate pentahydrate ACS 
dipotassium pentahydrate thiosulphate 
thiosulfuric acid, disodium salt 
Sodium thiosulfate hydrate (JP17) 
SODIUM THIOSULFATE, U.S.P. 
sodium sulfurothioate--water (1/5) 
AKOS015950633 
Sodium Thiosulfate (Industrial Grade) 
LS-2481 
RTR-033799 
TRA0018653 
BP-31031 
E539 
SODIUM THIOSULFATE PENTAHYDRATE 
S079 
SC-78803 
AB1002327 
TR-033799 
FT-0645119 
ST24049288 
D01091 
Sodium thiosulfate pentahydrate Biochemical grade 
J-000310 
Sodium thiosulfate pentahydrate, 99.5+%, ACS reagent 
10102-17-7 
Thiosulfuric acid (H2S2O3), sodium salt, hydrate (1:2:5) 
Sulfactol 
Sodium hyposulfite 
Sodothiol 
SODIUM THIOSULFATE 
null 
Mixture Name 
Sodium thiosulfate anhydrous 
sodium thiosulphate pentahydrate 
Sodium thiosulfate [JAN] 
Ametox 
Natriumhyposulfit 5-Hydrat 
Sodium thiosulfate solution 
Natriumthiosulfat-Pentahydrat 
Sodium-thiosulphate-pentahydrate 
O3-S2.2Na.5H2-O 
Thiosulfate de sodium pentahydrat 
disodium dioxido-oxo-sulfanylidene- 
CID61475 
SODIUM THIOSULFATE PEN-HYD HI-PU 2.5KG 
Sodium thiosulfate pentahydrate, 99% min. 500g 
Sodium thiosulfate, pentahydrate 
Sodium thiosulfate pentahydrate, 99%, ACS reagent - 1KG 1kg 
7772-98-7 
Sodium Thiosulphate Pentahydrate 99% pure confirming to BP/USP 500gm 
Literature

Title: Rapid determination of thiamine, riboflavin, niacinamide, pantothenic acid, pyridoxine, folic acid and ascorbic acid in Vitamins with Minerals Tablets by high-performance liquid chromatography with diode array detector.

Journal: Journal of pharmaceutical and biomedical analysis 20121101

Title: Evaluation of effectiveness of EDTA and sodium thiosulfate in removing metal toxicity toward sea urchin embryo-larval applying the TIE.

Journal: Chemosphere 20120901

Title: Cartilage labelling for mechanical testing in T-peel configuration.

Journal: International orthopaedics 20120701

Title: Maximal conservative therapy of calcific uremic ateriolopathy.

Journal: Clinical nephrology 20120701

Title: Hydroxocobalamin versus sodium thiosulfate for the treatment of acute cyanide toxicity in a swine (Sus scrofa) model.

Journal: Annals of emergency medicine 20120601

Title: Review article: management of cyanide poisoning.

Journal: Emergency medicine Australasia : EMA 20120601

Title: [C-ring cleavage of liquiritigenin extracted from licorice roots by an oxygen-tolerant bovine rumen bacterium strain Aeroto-Niu-O16].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20120501

Title: Use of cellular electrical impedance sensing to assess in vitro cytotoxicity of anticancer drugs in a human kidney cell nephrotoxicity model.

Journal: The Analyst 20120321

Title: Successful treatment of calcific uremic arteriolopathy with sodium thiosulfate in a renal transplant recipient.

Journal: Renal failure 20120101

Title: Vitamin C-silver: an environmentally benign choice for DNA visualization on polyacrylamide gels.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20120101

Title: Multi-intervention management of calciphylaxis: a report of 7 cases.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20111201

Title: Complete clearance of calciphylaxis following combined treatment with cinacalcet and sodium thiosulfate.

Journal: Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20111201

Title: Calciphylaxis: a severe complication of renal disease.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20111108

Title: Calciphylaxis, occurring 10 weeks after hypercalcaemia, in a patient with multiple myeloma.

Journal: British journal of haematology 20111001

Title: Acute, sublethal cyanide poisoning in mice is ameliorated by nitrite alone: complications arising from concomitant administration of nitrite and thiosulfate as an antidotal combination.

Journal: Chemical research in toxicology 20110718

Title: Effect of Azadirachta indica (neem), sodium thiosulphate and calcium chloride on changes in nitrogen transformations and inhibition of nitrification in soil incubated under laboratory conditions.

Journal: Chemosphere 20110301

Title: Effect of alpha-ketoglutarate on neurobehavioral, neurochemical and oxidative changes caused by sub-chronic cyanide poisoning in rats.

Journal: Neurochemical research 20110301

Title: Sodium thiosulfate exposure disrupts in vitro and in vivo heart development.

Journal: Frontiers in bioscience (Elite edition) 20110101

Title: Inappropriate use of D-values for determining biocidal activity of various antimicrobials.

Journal: Journal of food science 20110101

Title: Multidisciplinary treatment. A therapeutic option to treat calciphylaxis.

Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20110101

Title: [Cutaneous calciphylaxis].

Journal: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20101201

Title: Thermodynamic and kinetic study of the single extraction of mercury from soil using sodium-thiosulfate.

Journal: Talanta 20101015

Title: Hemodialysis complications of hydroxocobalamin: a case report.

Journal: Journal of medical toxicology : official journal of the American College of Medical Toxicology 20100601

Title: Effect of sodium thiosulfate on cisplatin removal after intra-arterial embolization with a lipiodol-platinum suspension for hepatocellular carcinoma.

Journal: Acta radiologica (Stockholm, Sweden : 1987) 20100501

Title: Hydroxocobalamin and sodium thiosulfate versus sodium nitrite and sodium thiosulfate in the treatment of acute cyanide toxicity in a swine (Sus scrofa) model.

Journal: Annals of emergency medicine 20100401

Title: Pilot study comparing the efficacy of two cleaning techniques in reducing environmental contamination with cyclophosphamide.

Journal: The Annals of occupational hygiene 20100401

Title: The effect of Tween 80 on eggshell permeabilization in Galleria mellonella (L.) (Lepidoptera, Pyralidae).

Journal: Cryo letters 20100101

Title: Hepatoblastoma, cisplatin, and ototoxicity: good news on deaf ears.

Journal: Cancer 20091215

Title: In vitro and in vivo protein-bound tyrosine nitration characterized by diagonal chromatography.

Journal: Molecular & cellular proteomics : MCP 20091201

Title: Optimization and validation of an ion-pair RP-HPLC-UV method for the determination of total free iodine in rabbit plasma: application to a pharmacokinetic study.

Journal: Biomedical chromatography : BMC 20091101

Title: Microalga Scenedesmus obliquus as a potential source for biodiesel production.

Journal: Applied microbiology and biotechnology 20090801

Title: Protective role of alpha-ketoglutarate against massive doses of cyanide in rats.

Journal: Journal of environmental biology 20090701

Title: Thiosulfate reduces calcium phosphate nephrolithiasis.

Journal: Journal of the American Society of Nephrology : JASN 20090601

Title: Artifactual sulfation of silver-stained proteins: implications for the assignment of phosphorylation and sulfation sites.

Journal: Molecular & cellular proteomics : MCP 20090301

Title: The effect of sodium thiosulfate administration on nephrocalcinosis in a rat model.

Journal: Journal of endourology 20090301

Title: Calciphylaxis in a patient with normal renal function: response to treatment with sodium thiosulfate.

Journal: Clinical and experimental dermatology 20090101

Title: Nephrogenic systemic fibrosis associated with gadoversetamide exposure: treatment with sodium thiosulfate.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20090101

Title: Calcific uremic arteriolopathy (calciphylaxis): successful treatment with sodium thiosulfate in spite of elevated serum phosphate.

Journal: Journal of cutaneous medicine and surgery 20090101

Title: Successful treatment of severe iatrogenic calcinosis cutis with intravenous sodium thiosulfate in a child affected by T-acute lymphoblastic leukemia.

Journal: Pediatric dermatology 20090101

Title: Influence of sample preservation on endotoxin measurement in water.

Journal: Water science and technology : a journal of the International Association on Water Pollution Research 20090101

Title: Auditory late effects of chemotherapy.

Journal: Cancer treatment and research 20090101

Title: Cisplatin overdose: toxicities and management.

Journal: Drug safety 20090101

Title: Sodium thiosulfate, bisphosphonates, and cinacalcet for calciphylaxis.

Journal: CANNT journal = Journal ACITN 20090101

Title: Calcific uraemic arteriolopathy: an update.

Journal: Current opinion in nephrology and hypertension 20081101

Title: Sodium thiosulfate, bisphosphonates, and cinacalcet for treatment of calciphylaxis.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20080801

Title: Combination of sodium thiosulphate, cinacalcet, and paricalcitol in the treatment of calciphylaxis with hyperparathyroidism.

Journal: The International journal of artificial organs 20080801

Title: The effects of sulfur-containing compounds and gemcitabine on the binding of cisplatin to plasma proteins and DNA determined by inductively coupled plasma mass spectrometry and high performance liquid chromatography-inductively coupled plasma mass spectrometry.

Journal: Anti-cancer drugs 20080701

Title: Selection of agents for prevention of cisplatin-induced hepatotoxicity.

Journal: Pharmacological research 20080201

Title: A spectroscopic investigation into the reaction of sodium tetrathionate with cysteine.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080101

Title: Cardioprotective role of sodium thiosulfate on chronic heart failure by modulating endogenous H2S generation.

Journal: Pharmacology 20080101

Title: Copper toxicosis in a dairy goat herd.

Journal: Journal of the American Veterinary Medical Association 20070815

Title: [Reader's letter on Marcus Meissner, Jens, Gille, Roland Kaufmann. Calciphylaxis: no therapeutic concepts for a poorly understood syndrome?].

Journal: Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20070501

Title: [Protective effect of melatonin and sodium thiosulphate on histopathology and ultrastructure of the kidney in rats with acute paraquat poisoning].

Journal: Investigacion clinica 20070301

Title: Oxidative stress pathways in the potentiation of noise-induced hearing loss by acrylonitrile.

Journal: Hearing research 20070201

Title: Degradation and detoxification of acetochlor in soils treated by organic and thiosulfate amendments.

Journal: Chemosphere 20070101

Title: [Sodium azide--clinical course of the poisoning and treatment].

Journal: Przeglad lekarski 20070101

Title: Comparison of effects of epigallocatechin-3-gallate on hypoxia injury to human umbilical vein, RF/6A, and ECV304 cells induced by Na(2)S(2)O(4).

Journal: Endothelium : journal of endothelial cell research 20070101

Title: Calciphylaxis: no therapeutic concepts for a poorly understood syndrome?

Journal: Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20061201

Title: Involvement of radical species in inactivation of Vibrio parahaemolyticus in saline solutions by direct-current electric treatment.

Journal: Journal of bioscience and bioengineering 20061101

Title: Sodium thiosulfate treatment for calcific uremic arteriolopathy in children and young adults.

Journal: Clinical journal of the American Society of Nephrology : CJASN 20061101

Title: Toxicity profile of delayed high dose sodium thiosulfate in children treated with carboplatin in conjunction with blood-brain-barrier disruption.

Journal: Pediatric blood & cancer 20060801

Title: Management of the cyanide-poisoned patient.

Journal: Journal of emergency nursing: JEN : official publication of the Emergency Department Nurses Association 20060801

Title: Enhanced contrast of bacteriophage plaques in Salmonella with ferric ammonium citrate and sodium thiosulfate (FACST) and tetrazolium red (TZR).

Journal: Journal of microbiological methods 20060501

Title: Flow-injection enhanced chemiluminescence method for determination of ciprofloxacin in pharmaceutical preparations and biological fluids.

Journal: Analytical and bioanalytical chemistry 20060301

Title: Toxicity identification evaluation of five metals performed with two organisms (Daphnia magna and Lactuca sativa).

Journal: Archives of environmental contamination and toxicology 20060201

Title: Sodium thiosulphate impairs the cytotoxic effects of cisplatin on FADU cells in culture.

Journal: The Journal of otolaryngology 20060201

Title: Effect of alpha-ketoglutarate on cyanide-induced biochemical alterations in rat brain and liver.

Journal: Biomedical and environmental sciences : BES 20060201

Title: Compounds of glycine with metal sulfates and thiosulfates: glycine cobalt sulfate pentahydrate, glycine sodium thiosulfate dihydrate and glycine potassium thiosulfate.

Journal: Acta crystallographica. Section C, Crystal structure communications 20060101

Title: Analysis of atmospheric sesquiterpenes: sampling losses and mitigation of ozone interferences.

Journal: Environmental science & technology 20051215

Title: Effect of sub-acute oral cyanide administration in rats: protective efficacy of alpha-ketoglutarate and sodium thiosulfate.

Journal: Chemico-biological interactions 20050910

Title: Protection against cisplatin-induced toxicities by N-acetylcysteine and sodium thiosulfate as assessed at the molecular, cellular, and in vivo levels.

Journal: The Journal of pharmacology and experimental therapeutics 20050901

Title: [Intraarterial concomitant chemoradiation for tongue cancer: analysis of 20 patients].

Journal: Nihon Jibiinkoka Gakkai kaiho 20050601

Title: Acceleration of cisplatin ototoxicity by perilymphatic application of 4-methylthiobenzoic acid.

Journal: Hearing research 20050501

Title: [Sodium thiosulfate for acute cyanide poisoning: study in a rat model].

Journal: Annales pharmaceutiques francaises 20050301

Title: [Extravasation of chemotherapeutic agents: prevention and therapy].

Journal: Deutsche medizinische Wochenschrift (1946) 20050107

Title: Identification of metal toxicity in sewage sludge leachate.

Journal: Environment international 20050101

Title: Multimodality treatment including postoperative radiation and concurrent chemotherapy with weekly docetaxel is feasible and effective in patients with oral and oropharyngeal cancer.

Journal: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20050101

Title: Vascular ossification-calcification in metabolic syndrome, type 2 diabetes mellitus, chronic kidney disease, and calciphylaxis-calcific uremic arteriolopathy: the emerging role of sodium thiosulfate.

Journal: Cardiovascular diabetology 20050101

Title: Determination of methyltestosterone using flow injection with chemiluminescence detection.

Journal: Luminescence : the journal of biological and chemical luminescence 20050101

Title: A study on the micelle-sensitized Ce(IV)-Na2S2O3-norfloxacin chemiluminescence system and its applications.

Journal: Luminescence : the journal of biological and chemical luminescence 20050101

Title: Revisiting the Bhopal tragedy.

Journal: Science (New York, N.Y.) 20041203

Title: Innovative therapies: intraoperative intracavitary chemotherapy.

Journal: Thoracic surgery clinics 20041101

Title: Persulfate oxidation for in situ remediation of TCE. I. Activated by ferrous ion with and without a persulfate-thiosulfate redox couple.

Journal: Chemosphere 20040601

Title: Nitric oxide donor sodium nitroprusside dilates rat small arteries by activation of inward rectifier potassium channels.

Journal: Hypertension (Dallas, Tex. : 1979) 20040401

Title: Round window application of D-methionine, sodium thiosulfate, brain-derived neurotrophic factor, and fibroblast growth factor-2 in cisplatin-induced ototoxicity.

Journal: Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 20040101

Title: [Physiotherapy in combined treatment of patients with genital tuberculosis].

Journal: Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury 20040101

Title: A new method using a bacterium for dissolution of urinary stones.

Journal: Aktuelle Urologie 20030701

Title: Re: Sodium thiosulfate in cisplatin overdose by Erdlenbruch B et al., Med Pediatr Oncol 2002;38:349-352.

Journal: Medical and pediatric oncology 20030601

Title: Quantification of sodium thiosulphate protection on cisplatin-induced toxicities.

Journal: The Journal of otolaryngology 20030601

Title: Efficient soybean transformation using hygromycin B selection in the cotyledonary-node method.

Journal: Planta 20030301

Title: Effect of methoxime combined with anticholinergic, anticonvulsant or anti-HCN drugs in tabun-poisoned mice.

Journal: Acta medica (Hradec Kralove) 20030101

Title: Strategies for prevention of toxicity caused by platinum-based chemotherapy: review and summary of the annual meeting of the Blood-Brain Barrier Disruption Program, Gleneden Beach, Oregon, March 10, 2001.

Journal: The Laryngoscope 20021101

Title: Chemoprotection profiles of sodium thiosulfate on methyl methanesulfonate-induced mutagenesis of bacteriophage T4.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20020601

Title: Reduction in intracanal bacteria during root canal preparation with and without apical enlargement.

Journal: International endodontic journal 20020501

Title: An effective method of inactivating chlorhexidine.

Journal: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20020501

Title: In vitro and in vivo attenuation of experimental cyanide poisoning by alpha-ketoglutarate.

Journal: Toxicology letters 20020310

Title: The effect of 10% povidone--iodine solution on contaminated bone allografts.

Journal: The Journal of hospital infection 20020301

Title: [Present role and future prospect of superselective intra-arterial infusion chemotherapy for head and neck cancer].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20020201

Title: Disinfection of wastewater by hydrogen peroxide or peracetic acid: development of procedures for measurement of residual disinfectant and application to a physicochemically treated municipal effluent.

Journal: Water environment research : a research publication of the Water Environment Federation 20020101

Title: Sulfate transport in porcine thyroid cells. Effects of thyrotropin and iodide.

Journal: American journal of physiology. Endocrinology and metabolism 20010901

Title: Determination of molecular sulphur in sodium thiosulphate injection solutions by high performance liquid chromatography.

Journal: Die Pharmazie 20010701

Title: Rescue from enhanced alkylator-induced cell death with low molecular weight sulfur-containing chemoprotectants.

Journal: The Journal of pharmacology and experimental therapeutics 20010301

Title: Delayed sodium thiosulfate as an otoprotectant against carboplatin-induced hearing loss in patients with malignant brain tumors.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20010301

Title: Oxidation of p-hydroxybenzoic acid by Fenton's reagent.

Journal: Water research 20010201

Title: [Very high frequency electromagnetic irradiation in multimodal treatment of patients with disseminated infiltrative pulmonary tuberculosis].

Journal: Problemy tuberkuleza 20010101

Title: Chemoprotection and interindividual differences in response to biological reactive intermediates.

Journal: Advances in experimental medicine and biology 20010101

Title: First evidence of otoprotection against carboplatin-induced hearing loss with a two-compartment system in patients with central nervous system malignancy using sodium thiosulfate.

Journal: The Journal of pharmacology and experimental therapeutics 19980701

Title: The antidotal action of sodium nitrite and sodium thiosulfate against cyanide poisoning.

Journal: Journal of clinical pharmacology 19920401

Title: Sodium thiosulphate decreases blood cyanide concentrations after the infusion of sodium nitroprusside.

Journal: British journal of anaesthesia 19870501

Title: Hydroxycobalamin/sodium thiosulfate as a cyanide antidote.

Journal: The Journal of emergency medicine 19870101

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