Home Other Building Blocks 1011557-82-6
1011557-82-6,MFCD11976906
Catalog No.:AA0003RW
1011557-82-6 | Tenovin-6
Pack Size
Purity
Availability
Price(USD)
Quantity
  
2mg
98%
1 week  
$146.00   $102.00
- +
5mg
98%
1 week  
$177.00   $124.00
- +
10mg
98%
1 week  
$209.00   $147.00
- +
50mg
98%
1 week  
$511.00   $358.00
- +
100mg
98%
1 week  
$828.00   $580.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Q & A
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0003RW
Chemical Name:
Tenovin-6
CAS Number:
1011557-82-6
Molecular Formula:
C25H34N4O2S
Molecular Weight:
454.6281
MDL Number:
MFCD11976906
IUPAC Name:
4-tert-butyl-N-[[4-[5-(dimethylamino)pentanoylamino]phenyl]carbamothioyl]benzamide
InChI:
InChI=1S/C25H34N4O2S/c1-25(2,3)19-11-9-18(10-12-19)23(31)28-24(32)27-21-15-13-20(14-16-21)26-22(30)8-6-7-17-29(4)5/h9-16H,6-8,17H2,1-5H3,(H,26,30)(H2,27,28,31,32)
InChI Key:
BVJSXSQRIUSRCO-UHFFFAOYSA-N
SMILES:
CN(CCCCC(=O)Nc1ccc(cc1)NC(=S)NC(=O)c1ccc(cc1)C(C)(C)C)C
Properties
Computed Properties
 
Complexity:
616  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
454.24g/mol
Formal Charge:
0
Heavy Atom Count:
32  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
454.633g/mol
Monoisotopic Mass:
454.24g/mol
Rotatable Bond Count:
9  
Topological Polar Surface Area:
106A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
5.1  

Synonyms
 
N-((4-(5-(dimethylamino)-(1-(oxopentyl)amino)phenyl)amino)thioxomethyl)-(4-(1,1-dimethylethyl)benzamide) 
tenovin-6 
4-tert-butyl-N-(4-(5-(dimethylamino)pentanamido)phenylcarbamothioyl)benzamide 
4-tert-butyl-N-[(4-{[5-(dimethylamino)pentanoyl]amino}phenyl)carbamothioyl]benzamide 
Tenovin6 
Tnv 6 
SCHEMBL907478 
US8501991, Tenovin 6 
BDBM99917 
CTK8E8404 
AOB3690 
DTXSID50647242 
Tenovin-6 
EX-A350 
BVJSXSQRIUSRCO-UHFFFAOYSA-N 
HMS3648C14 
HMS3652F12 
BCP08547 
BCP21202 
2064AH 
ZINC43196009 
AKOS026750220 
CCG-208692 
1011557-82-6 
CS-1976 
NCGC00263616-04 
4CA-1231 
AK175449 
AS-16762 
BC600393 
Benzamide, N-[[[4-[[5-(dimethylamino)-1-oxopentyl]amino]phenyl]amino]thioxomethyl]-4-(1,1-dimethylethyl)- 
DA-48390 
HY-15510 
QC-10485 
Tenovin 6 
AB0098114 
RT-017591 
FT-0708864 
SW220061-1 
A12305 
SR-01000946351 
J-000331 
SR-01000946351-1 
4-(tert-butyl)-N-((4-(5-(dimethylamino)pentanamido)phenyl)carbamothioyl)benzamide 
N-[[[4-[[5-(Dimethylamino)-1-oxopentyl]amino]phenyl]amino]thioxomethyl]-4-(1,1-dimethylethyl)-benzamide 
CHEMBL595354 
Amfonelic acid 
ACN-029577 
A8302 
Tenovin-6, 98%, SIRT inhibitor and p53 activator - 1MG 1mg 
15180-02-6 
CHEBI:77729 
MFCD11976906 
4-tert-Butyl-N-[[4-[5-(dimethylamino)pentanoylamino]phenyl]carbamothioyl]benzamide 
C25H34N4O2S 
Literature

Title: An evaluation of small-molecule p53 activators as chemoprotectants ameliorating adverse effects of anticancer drugs in normal cells.

Journal: Cell cycle (Georgetown, Tex.) 20120501

Title: Identification and characterization of novel sirtuin inhibitor scaffolds.

Journal: Bioorganic & medicinal chemistry 20091001

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