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Home Amines 101187-40-0
101187-40-0,MFCD16619220
Catalog No.:AA0003U9

101187-40-0 | 13-Amino-5,8,11-trioxa-2-azatridecanoic acid 1,1-dimethylethyl ester

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Purity
Availability
Price(USD)
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100mg
95%
in stock  
$8.00   $6.00
- +
250mg
97%
in stock  
$10.00   $7.00
- +
1g
95%
in stock  
$23.00   $16.00
- +
5g
97%
in stock  
$80.00   $56.00
- +
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0003U9
Chemical Name:
13-Amino-5,8,11-trioxa-2-azatridecanoic acid 1,1-dimethylethyl ester
CAS Number:
101187-40-0
Molecular Formula:
C13H28N2O5
Molecular Weight:
292.3718
MDL Number:
MFCD16619220
SMILES:
NCCOCCOCCOCCNC(=O)OC(C)(C)C
Properties
Computed Properties
 
Complexity:
243  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
13  
XLogP3:
-0.5  

Upstream Synthesis Route

[1]Tetrahedron,2012,vol.68,#52,p.10818-10826

[2]JournaloftheAmericanChemicalSociety,2001,vol.123,#37,p.8914-8922

[3]BioorganicandMedicinalChemistry,2002,vol.10,#3,p.625-637

[4]BioorganicandMedicinalChemistryLetters,2002,vol.12,#6,p.853-856

[5]JournaloftheAmericanChemicalSociety,2015,vol.137,#28,p.9108-9116

[6]Patent:EP1783137,2007,A1,.Locationinpatent:Page/Pagecolumn24

[7]Patent:US2018/169262,2018,A1,.Locationinpatent:Paragraph0173;0174

[1]Patent:EP3173408,2017,A1,.Locationinpatent:Paragraph0328

[2]JournaloftheAmericanChemicalSociety,2012,vol.134,#1,p.83-86

[1]Patent:WO2005/30258,2005,A2,.Locationinpatent:Page/Pagecolumn115

[1]Patent:US2012/121615,2012,A1,

[1]JournalofOrganicChemistry,2001,vol.66,#11,p.3709-3716

Downstream Synthesis Route

[1]JournalofOrganicChemistry,2007,vol.72,p.1675-1680

945920-86-5    101187-40-0   
C60H76N22O10C2H4C2O2C2H4NH(OC2H4)3NHCO2C4H8 

[1]AngewandteChemie-InternationalEdition,2007,vol.46,p.4382-4384

[1]JournalofOrganicChemistry,2007,vol.72,p.1675-1680

101187-40-0   
4-2-(2-{2-(3-amino-propyl)-(2-{2-2-(2-<i>tert</i>-butoxycarbonylamino-ethoxy)-ethoxy-ethoxy}-ethyl)-amino-ethoxy}-ethoxy)-ethoxy-butyricacidmethylester 

[1]JournalofOrganicChemistry,2007,vol.72,p.1675-1680

101187-40-0   
4-2-(2-{2-(2-{2-2-(2-<i>tert</i>-butoxycarbonylamino-ethoxy)-ethoxy-ethoxy}-ethyl)-(3-ethylamino-propyl)-amino-ethoxy}-ethoxy)-ethoxy-butyricacidmethylester 

[1]JournalofOrganicChemistry,2007,vol.72,p.1675-1680

Literature

Title: An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

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SDS
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Tags:101187-40-0 Molecular Formula|101187-40-0 MDL|101187-40-0 SMILES|101187-40-0 13-Amino-5,8,11-trioxa-2-azatridecanoic acid 1,1-dimethylethyl ester