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Title: Acetylcholinesterase deficiency contributes to neuromuscular junction dysfunction in type 1 diabetic neuropathy.
Journal: American journal of physiology. Endocrinology and metabolism 20120815
Title: Synthesis of phenserine analogues and evaluation of their cholinesterase inhibitory activities.
Journal: Bioorganic & medicinal chemistry 20120815
Title: Synthesis of (+)-phenserine using an interrupted Fischer indolization reaction.
Journal: The Journal of organic chemistry 20120106
Title: Acetylcholinesterase inhibition ameliorates deficits in motivational drive.
Journal: Behavioral and brain functions : BBF 20120101
Title: Lithium, phenserine, memantine and pioglitazone reverse memory deficit and restore phospho-GSK3β decreased in hippocampus in intracerebroventricular streptozotocin induced memory deficit model.
Journal: Brain research 20111202
Title: Molybdenum-catalyzed asymmetric allylic alkylation of 3-alkyloxindoles: reaction development and applications.
Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20110301
Title: Cholinesterase inhibitors improve both memory and complex learning in aged beagle dogs.
Journal: Journal of Alzheimer's disease : JAD 20110101
Title: Novel carbamates as orally active acetylcholinesterase inhibitors found to improve scopolamine-induced cognition impairment: pharmacophore-based virtual screening, synthesis, and pharmacology.
Journal: Journal of medicinal chemistry 20100909
Title: Synthesis of physostigmine analogues and evaluation of their anticholinesterase activities.
Journal: Bioorganic & medicinal chemistry letters 20100301
Title: Phenserine efficacy in Alzheimer's disease.
Journal: Journal of Alzheimer's disease : JAD 20100101
Title: Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): identification of phenmedipham and amperozide as FAAH inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20091201
Title: The perils of Alzheimer's drug development.
Journal: Current Alzheimer research 20090201
Title: Accommodation of physostigmine and its analogues by acetylcholinesterase is dominated by hydrophobic interactions.
Journal: The Biochemical journal 20090101
Title: How to approach Alzheimer's disease therapy using stem cell technologies.
Journal: Journal of Alzheimer's disease : JAD 20081001
Title: Effect of phenserine treatment on brain functional activity and amyloid in Alzheimer's disease.
Journal: Annals of neurology 20080501
Title: Phenserine.
Journal: Expert opinion on investigational drugs 20070701
Title: Preclinical investigation of the topical administration of phenserine: transdermal flux, cholinesterase inhibition, and cognitive efficacy.
Journal: The Journal of pharmacology and experimental therapeutics 20070401
Title: Total synthesis of (+/-) -phenserine via [4+1] cyclization of a bis(alkylthio)carbene and an indole isocyanate.
Journal: Organic letters 20070329
Title: The experimental Alzheimer's disease drug posiphen [(+)-phenserine] lowers amyloid-beta peptide levels in cell culture and mice.
Journal: The Journal of pharmacology and experimental therapeutics 20070101
Title: Differential effects of two hexahydropyrroloindole carbamate-based anticholinesterase drugs on the amyloid beta protein pathway involved in Alzheimer's disease.
Journal: Neuromolecular medicine 20070101
Title: Kinetics of human serum butyrylcholinesterase and its inhibition by a novel experimental Alzheimer therapeutic, bisnorcymserine.
Journal: Journal of Alzheimer's disease : JAD 20060901
Title: Identification of novel small molecule inhibitors of amyloid precursor protein synthesis as a route to lower Alzheimer's disease amyloid-beta peptide.
Journal: The Journal of pharmacology and experimental therapeutics 20060801
Title: Palladium-catalyzed enantioselective C-3 allylation of 3-substituted-1H-indoles using trialkylboranes.
Journal: Journal of the American Chemical Society 20060517
Title: Novel cholinesterase inhibitors as future effective drugs for the treatment of Alzheimer's disease.
Journal: Expert opinion on investigational drugs 20060101
Title: Anticholinesterase and pharmacokinetic profile of phenserine in healthy elderly human subjects.
Journal: Current Alzheimer research 20051001
Title: An overview of phenserine tartrate, a novel acetylcholinesterase inhibitor for the treatment of Alzheimer's disease.
Journal: Current Alzheimer research 20050701
Title: Phenserine Axonyx.
Journal: Current opinion in investigational drugs (London, England : 2000) 20050701
Title: Further evidence for the cholinergic hypothesis of aging and dementia from the canine model of aging.
Journal: Progress in neuro-psychopharmacology & biological psychiatry 20050301
Title: Novel anticholinesterases based on the molecular skeletons of furobenzofuran and methanobenzodioxepine.
Journal: Journal of medicinal chemistry 20050224
Title: The cholinesterase inhibitor, phenserine, improves Morris water maze performance of scopolamine-treated rats.
Journal: Life sciences 20050121
Title: The integrated role of desferrioxamine and phenserine targeted to an iron-responsive element in the APP-mRNA 5'-untranslated region.
Journal: Annals of the New York Academy of Sciences 20041201
Title: Asymmetric synthesis of pyrrolidinoindolines. Application for the practical total synthesis of (-)-phenserine.
Journal: Journal of the American Chemical Society 20041103
Title: Sensitivity of [11C]N-methylpyrrolidinyl benzilate ([11C]NMPYB) to endogenous acetylcholine: PET imaging vs tissue sampling methods.
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Title: (R)-N-[11C]methyl-3-pyrrolidyl benzilate, a high-affinity reversible radioligand for PET studies of the muscarinic acetylcholine receptor.
Journal: Synapse (New York, N.Y.) 20020701
Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
Journal: The Journal of biological chemistry 20020419
Title: Methyl analogues of the experimental Alzheimer drug phenserine: synthesis and structure/activity relationships for acetyl- and butyrylcholinesterase inhibitory action.
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Title: Acetylcholinesterase inhibition increases in vivo N-(2-[18F]fluoroethyl)-4-piperidyl benzilate binding to muscarinic acetylcholine receptors.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20010201
Title: Phenserine (Axonyx/NIH).
Journal: IDrugs : the investigational drugs journal 20001001
