Home Amines 101421-72-1
101421-72-1,MFCD10697883
Catalog No.:AA0004DX

101421-72-1 | 6-Aminoquinazoline

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
98%
in stock  
$112.00   $78.00
- +
250mg
98%
in stock  
$137.00   $96.00
- +
1g
98%
in stock  
$303.00   $212.00
- +
5g
98%
in stock  
$926.00   $648.00
- +
25g
98%
in stock  
$3,253.00   $2,277.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0004DX
Chemical Name:
6-Aminoquinazoline
CAS Number:
101421-72-1
Molecular Formula:
C8H7N3
Molecular Weight:
145.1613
MDL Number:
MFCD10697883
SMILES:
Nc1ccc2c(c1)cncn2
Properties
Properties
 
BP:
335.9°C at 760 mmHg  
Form:
Solid  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
137  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
XLogP3:
0.3  

Downstream Synthesis Route
101421-72-1    261904-39-6   
(R)-3-bromo-2-hydroxy-2-methyl-N-(quinazolin-6-yl)propanamide 

[1]Patent:WO2017/214634,2017,A1.Locationinpatent:Paragraph00402-00403

Literature

Title: Specific PKC isoforms regulate LPS-stimulated iNOS induction in murine microglial cells.

Journal: Journal of neuroinflammation 20110101

Title: Combinatorial effect of non-steroidal anti-inflammatory drugs and NF-κB inhibitors in ovarian cancer therapy.

Journal: PloS one 20110101

Title: Critical role of macrophages and their activation via MyD88-NFκB signaling in lung innate immunity to Mycoplasma pneumoniae.

Journal: PloS one 20100101

Title: The combi-targeting concept: evidence for the formation of a novel inhibitor in vivo.

Journal: Anti-cancer drugs 20060201

Title: Fluorescence and analytical ultracentrifugation analyses of the interaction of the tyrosine kinase inhibitor, tyrphostin AG 1478-mesylate, with albumin.

Journal: Analytical biochemistry 20050715

Title: A novel structural class of potent inhibitors of NF-kappa B activation: structure-activity relationships and biological effects of 6-aminoquinazoline derivatives.

Journal: Bioorganic & medicinal chemistry 20030901

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SDS
Tags:101421-72-1 Molecular Formula|101421-72-1 MDL|101421-72-1 SMILES|101421-72-1 6-Aminoquinazoline