Home Other Building Blocks 101827-46-7
101827-46-7,MFCD00917064
Catalog No.:AA0005KW
101827-46-7 | Butenafine HCl
Pack Size
Purity
Availability
Price(USD)
Quantity
  
250mg
≥98%
in stock  
$111.00   $78.00
- +
1g
98%(HPLC)
in stock  
$139.00   $97.00
- +
5g
98%(HPLC)
in stock  
$410.00   $287.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Q & A
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0005KW
Chemical Name:
Butenafine HCl
CAS Number:
101827-46-7
Molecular Formula:
C23H28ClN
Molecular Weight:
353.9281
MDL Number:
MFCD00917064
IUPAC Name:
1-(4-tert-butylphenyl)-N-methyl-N-(naphthalen-1-ylmethyl)methanamine;hydrochloride
InChI:
InChI=1S/C23H27N.ClH/c1-23(2,3)21-14-12-18(13-15-21)16-24(4)17-20-10-7-9-19-8-5-6-11-22(19)20;/h5-15H,16-17H2,1-4H3;1H
InChI Key:
LJBSAUIFGPSHCN-UHFFFAOYSA-N
SMILES:
CN(Cc1cccc2c1cccc2)Cc1ccc(cc1)C(C)(C)C.Cl
UNII:
R8XA2029ZI
Properties
Computed Properties
 
Complexity:
374  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
353.191g/mol
Formal Charge:
0
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
353.934g/mol
Monoisotopic Mass:
353.191g/mol
Rotatable Bond Count:
5  
Topological Polar Surface Area:
3.2A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0

Synonyms
 
butenafine 
butenafine hydrochloride 
KP-363 
Butenafine hydrochloride, 99% - 1G 1g 
B1901 
101828-21-1 
1-(4-tert-butylphenyl)-N-methyl-N-(1-naphthylmethyl)methanamine 
1-Naphthalenemethanamine, N-((4-(1,1-dimethylethyl)phenyl)methyl)-N-methyl-, hydrochloride 
Butenafine (Hydrochloride) 
UNII-R8XA2029ZI 
CHEBI:31325 
N-(p-tert-Butylbenzyl)-N-methyl-1-naphthalenemethylamine hydrochloride 
R8XA2029ZI 
N-4-tert-Butylbenzyl-N-methyl-1-naphthalenemethylamine hydrochloride 
1-(4-tert-butylphenyl)-N-methyl-N-(naphthalen-1-ylmethyl)methanamine hydrochloride 
N-((4-(1,1-Dimethylethyl)phenyl)methyl)-N-methyl-1-naphthalenemethanamine hydrochloride 
N-[[4-(1,1-Dimethylethyl)phenyl]methyl]-N-methyl-1-naphthalenemethanamine hydrochloride 
KP 363 
N-(4-t-Butylbenzyl)-N-methyl-1-naphthalenemethylamine hydrochloride;N-(4-t-Butylbenzyl)-N-methyl-1-naphthalenemethylamine hydrochloride 
Butenafine hydrochloide 
Scorba 
Volley 
1-(4-tert-butylphenyl)-N-methyl-N-(1-naphthalenylmethyl)methanamine hydrochloride 
Butenafine hydrochloride [USAN:JAN] 
Mentax (TN) 
Volley (TN) 
butenafine-hydrochloride 
AC1L9FCX 
KP-363 
SureCN1648813 
DSSTox_CID_28515 
DSSTox_RID_82787 
DSSTox_GSID_48589 
MLS003899213 
SCHEMBL262301 
CHEMBL1200397 
DTXSID2048589 
CTK8B3383 
KS-00000FUA 
Mentax 
LJBSAUIFGPSHCN-UHFFFAOYSA-N 
BCP22699 
Tox21_112918 
ANW-42439 
BG0596 
s3154 
AKOS015895328 
AB07686 
AC-2116 
API0001792 
N-4-tert-butylbenzyl-N-methyl-1-naphthalene methylamine hydrochloride 
BCP9000464 
Butenafine hydrochloride (JP17/USAN) 
CCG-220604 
CS-1124 
KS-1035 
RTR-000443 
1-Naphthalenemethanamine, N-[[4-(1,1-dimethylethyl)phenyl]methyl]-N-methyl-, hydrochloride (1:1) 
AK608062 
AN-14303 
BC205781 
Butenafine hydrochloride 
CC-25280 
HY-17396 
SC-17334 
SMR002204106 
Butenafine hydrochloride, >=98% (HPLC) 
AB0106850 
TR-000443 
CAS-101827-46-7 
FT-0631017 
FT-0699734 
101827-46-7 
SW199070-2 
A11829 
C12490 
D01093 
K-0256 
827B467 
A800463 
A800464 
I06-0721 
J-000499 
Butenafine HCL 
4-tert-butylbenzyl(methyl)(1-naphthalenemethyl)amine hydrochloride 
N-(4-tert-butylbenzyl)-N-methyl-1-naphthylmethylamine hydrochloride 
N-4-t-butylbenzyl-N-methyl-1-naphthalenemethylamine hydrochloride 
(4-tert-butylphenyl)-N-methyl-N-(naphthalen-1-ylmethyl)methanaminium chloride 
1-(4-tert-butylphenyl)-N-methyl-N-(1-naphthylmethyl)methanamine hydrochloride 
1-(4-tert-butylphenyl)-N-methyl-N-(naphthalen-1-ylmethyl)methanamine;hydrochloride 
N-(4-(tert-butyl)benzyl)-N-methyl-1-(naphthalen-1-yl)methanamine hydrochloride 
N-(4-tert-butylbenzyl)-N-methyl-1-(naphthalen-1-yl)methanamine hydrochloride 
butenafine 
hydrochloride 
Mentax 
Mentax-TC 
Lotrimin U Ultra 
BUTENAFINEHYDROCHLORIDE 
C23-H27-N.Cl-H 
Butenafine hydrochloride [USAN] 
CID443867 
MFCD00917064 
ACN-034399 
CS-O-11614 
NCGC00181746-01 
Literature

Title: Chiral N-benzyl-N-methyl-1-(naphthalen-1-yl)ethanamines and their in vitro antifungal activity against Cryptococcus neoformans, Trichophyton mentagrophytes and Trichophyton rubrum.

Journal: European journal of medicinal chemistry 20131001

Title: Determination of butenafine hydrochloride in human plasma by liquid chromatography electrospray ionization-mass spectrometry following its topical administration in human subjects.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111115

Title: A simple and rapid method to assess butenafine hydrochloride in skin samples and a comparative cutaneous retention study of two marketed formulations.

Journal: Biomedical chromatography : BMC 20111001

Title: Stability-indicating LC assay for butenafine hydrochloride in creams using an experimental design for robustness evaluation and photodegradation kinetics study.

Journal: Journal of chromatographic science 20110801

Title: RP-HPLC method for simultaneous determination of butenafine hydrochloride and betamethasone dipropionate in a cream formulation.

Journal: Journal of AOAC International 20110101

Title: [Activity of butenafine against ocular pathogenic filamentous fungi in vitro].

Journal: [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20100101

Title: Butenafine and superficial mycoses: current status.

Journal: Expert opinion on drug metabolism & toxicology 20080701

Title: An unprecedented rearrangement in collision-induced mass spectrometric fragmentation of protonated benzylamines.

Journal: Journal of mass spectrometry : JMS 20060901

Title: [The effect of propyl gallate on the activity of various antifungal drugs against filamentous fungi in vitro].

Journal: [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20060401

Title: In vitro antifungal activity of ZJ-522, a new triazole restructured from fluconazole and butenafine, against clinically important fungi in comparison with fluconazole and butenafine.

Journal: Biological & pharmaceutical bulletin 20050801

Title: Comparative efficacy of topical 1% butenafine and 1% clotrimazole in tinea cruris and tinea corporis: a randomized, double-blind trial.

Journal: The Journal of dermatological treatment 20050101

Title: Evaluation of in vitro activity of ciclopirox olamine, butenafine HCl and econazole nitrate against dermatophytes, yeasts and bacteria.

Journal: International journal of dermatology 20030901

Title: Butenafine: an update of its use in superficial mycoses.

Journal: Skin therapy letter 20020901

Title: Experimental and conformational analyses of interactions between butenafine and lipids.

Journal: Antimicrobial agents and chemotherapy 20011201

Title: Efficacy and safety of butenafine in superficial dermatophytoses (tinea pedis, tinea cruris, tinea corporis).

Journal: Journal of the Indian Medical Association 20010501

Title: Butenafine hydrochloride (Mentax) cream for the treatment of hyperkeratotic type tinea pedis and its transfer into the horny layer, with or without concomitant application of 20% urea ointment (Keratinamin).

Journal: Mycoses 20010101

Title: Azole antifungal agents related to naftifine and butenafine.

Journal: Archiv der Pharmazie 20000601

Title: Butenafine hydrochloride: for the treatment of interdigital tinea pedis.

Journal: Expert opinion on pharmacotherapy 20000301

Title: Butenafine, a fungicidal benzylamine derivative, used once daily for the treatment of interdigital tinea pedis.

Journal: International journal of dermatology 19980601

Title: Butenafine.

Journal: Drugs 19980301

Title: Two mechanisms of butenafine action in Candida albicans.

Journal: Antimicrobial agents and chemotherapy 19930401

Title: [Synthesis and antifungal activity of butenafine hydrochloride (KP-363), a new benzylamine antifungal agent].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 19910201

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Additional Info:
Q & A