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1019331-10-2,MFCD23136018
Catalog No.:AA0005XN

1019331-10-2 | 2-Chloro-N-({4-[2-(cyanosulfamoyl)phenyl]phenyl}methyl)-N-[(4-methylphenyl)methyl]benzamide

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥95%
in stock  
$45.00   $31.00
- +
5mg
≥95%
in stock  
$120.00   $84.00
- +
10mg
≥95%
in stock  
$215.00   $150.00
- +
25mg
≥95%
in stock  
$480.00   $336.00
- +
250mg
95%
in stock  
$4,012.00   $2,809.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0005XN
Chemical Name:
2-Chloro-N-({4-[2-(cyanosulfamoyl)phenyl]phenyl}methyl)-N-[(4-methylphenyl)methyl]benzamide
CAS Number:
1019331-10-2
Molecular Formula:
C29H24ClN3O3S
Molecular Weight:
530.0372
MDL Number:
MFCD23136018
SMILES:
N#CNS(=O)(=O)c1ccccc1c1ccc(cc1)CN(C(=O)c1ccccc1Cl)Cc1ccc(cc1)C
Properties
Computed Properties
 
Complexity:
897  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
37  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
8  
XLogP3:
6  

Literature

Title: Larsen AM, Krogsgaard-Larsen N, Lauritzen G, et al. Gram-scale solution-phase synthesis of selective sodium bicarbonate co-transport inhibitor S0859: in vitro efficacy studies in breast cancer cells. ChemMedChem. 2012 Oct;7(10):1808-14.

Title: Lauritzen G, Stock CM, Lemaire J, et al. The Na+/H+ exchanger NHE1, but not the Na+, HCO3(-) cotransporter NBCn1, regulates motility of MCF7 breast cancer cells expressing constitutively active ErbB2. Cancer Lett. 2012 Apr 28;317(2):172-83.

Title: Kumar S, Flacke JP, Kostin S, et al. SLC4A7 sodium bicarbonate co-transporter controls mitochondrial apoptosis in ischaemic coronary endothelial cells. Cardiovasc Res. 2011 Feb 1;89(2):392-400.

Title: Ch'en FF, Villafuerte FC, Swietach P, et al. S0859, an N-cyanosulphonamide inhibitor of sodium-bicarbonate cotransport in the heart. Br J Pharmacol. 2008 Mar;153(5):972-82.

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Tags:1019331-10-2 Molecular Formula|1019331-10-2 MDL|1019331-10-2 SMILES|1019331-10-2 2-Chloro-N-({4-[2-(cyanosulfamoyl)phenyl]phenyl}methyl)-N-[(4-methylphenyl)methyl]benzamide