Title: Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474.
Journal: Science (New York, N.Y.) 20170609
Title: Inhibition of fatty acid amide hydrolase (FAAH) as a novel therapeutic strategy in the treatment of pain and inflammatory diseases in the gastrointestinal tract.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20140214
Title: Elevating endocannabinoid levels: pharmacological strategies and potential therapeutic applications.
Journal: The Proceedings of the Nutrition Society 20140201
Title: An efficient randomised, placebo-controlled clinical trial with the irreversible fatty acid amide hydrolase-1 inhibitor PF-04457845, which modulates endocannabinoids but fails to induce effective analgesia in patients with pain due to osteoarthritis of the knee.
Journal: Pain 20120901
Title: Assessment of the pharmacology and tolerability of PF-04457845, an irreversible inhibitor of fatty acid amide hydrolase-1, in healthy subjects.
Journal: British journal of clinical pharmacology 20120501
Title: Peripheral FAAH inhibition causes profound antinociception and protects against indomethacin-induced gastric lesions.
Journal: Pharmacological research 20120501
Title: Mechanistic and pharmacological characterization of PF-04457845: a highly potent and selective fatty acid amide hydrolase inhibitor that reduces inflammatory and noninflammatory pain.
Journal: The Journal of pharmacology and experimental therapeutics 20110701
Title: Discovery of PF-04457845: A Highly Potent, Orally Bioavailable, and Selective Urea FAAH Inhibitor.
Journal: ACS medicinal chemistry letters 20110210
Title: Pharmacotherapeutic modulation of the endocannabinoid signalling system in psychiatric disorders: drug-discovery strategies.
Journal: International review of psychiatry (Abingdon, England) 20090401
113728-71-5 | 2,2':5',2'':5'',2''':5''',2'''':5'''',2''''':5''''',2'''''':5'''''',2'''''''-Octithiophene | AA0009EJ | MFCD09038539
1142223-08-2 | Benzenepropanoic acid, beta-cyclopropyl-3-hydroxy-, methyl ester, (betas)- | AA000ASC | MFCD27956898