Home Fluorides 10212-20-1
10212-20-1,MFCD00057445
Catalog No.:AA0006LX
10212-20-1 | 2'-Deoxy-2'-fluorocytidine
Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
97%
in stock  
$57.00   $40.00
- +
5g
97%
in stock  
$215.00   $150.00
- +
25g
97%
in stock  
$953.00   $667.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Q & A
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0006LX
Chemical Name:
2'-Deoxy-2'-fluorocytidine
CAS Number:
10212-20-1
Molecular Formula:
C9H12FN3O4
Molecular Weight:
245.2077
MDL Number:
MFCD00057445
IUPAC Name:
4-amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
InChI:
InChI=1S/C9H12FN3O4/c10-6-7(15)4(3-14)17-8(6)13-2-1-5(11)12-9(13)16/h1-2,4,6-8,14-15H,3H2,(H2,11,12,16)/t4-,6-,7-,8-/m1/s1
InChI Key:
NVZFZMCNALTPBY-XVFCMESISA-N
SMILES:
OC[C@H]1O[C@H]([C@@H]([C@@H]1O)F)n1ccc(nc1=O)N
UNII:
LCY080JPY9
Properties
Computed Properties
 
Complexity:
386  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Defined Bond Stereocenter Count:
0
Exact Mass:
245.081g/mol
Formal Charge:
0
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
245.21g/mol
Monoisotopic Mass:
245.081g/mol
Rotatable Bond Count:
2  
Topological Polar Surface Area:
108A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-1.1  

Synonyms
 
2'-deoxy-2'-fluorocytidine 
2'-fluoro-2'-deoxycytidine 
2 -Deoxy-2 -Fluorocytidine 
NSC 529432 
4-amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one 
NSC529432 
4-Amino-1-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one 
AK-25258 
2'-fluoro-d-cytidine 
PubChem14204 
2'deoxy-2'-fluorocytidine 
AC1L2QZ7 
2'-Deoxy-2'-fluorocytidine 
2'-FdC 
KSC494G2F 
SCHEMBL233120 
2'-Deoxy-2'-Fluorocytidine(2'-Fluoro-2'- Deoxycytidine, 2'-FC) 
2'-Fluoro -2'-deoxycytidine 
CHEMBL374528 
2\'-Deoxy-2\'-fluorocytidine 
2'-deoxy-2'-fluoro-d-cytidine 
CTK3J4322 
KS-00000JVN 
10212-20-1 
NVZFZMCNALTPBY-XVFCMESISA-N 
2'-FC 
2'-Deoxy-2'-fluorocytidineHydrate 
2'-deoxy-2'-(R)-fluoro-cytidine 
KS-00000Y9N 
ZINC3817231 
ANW-44828 
CF-209 
HG1103 
AKOS015854842 
2'-Fluoro-2'-deoxycytidine 
AKOS015896915 
.beta.-D-2'-Deoxy-2'-fluorocytidine 
AB02319 
ACN-055192 
RP28688 
RTX-011689 
AJ-45716 
CJ-10778 
AX8008057 
ST2403542 
Cytidine, 2'-deoxy-2'-fluoro- 
FT-0601651 
K-0284 
212D201 
3-[(2R,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-amino-3-hydropyrimidin-2-one 
4-amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2-one 
Ancitabin hydrochloride 
2-Deoxy-2-fluorocytidine 
2'-Fluoro-2'-deoxy-cytidine 
C9H12FN3O4 
2/'-Fluoro-2/'-deoxycytidine 
4-amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one 
C9-H12-F-N3-O4 
AR-1E1077 
CID101507 
56632-83-8 
102613-41-2 
FDC 
UNII-LCY080JPY9 
LCY080JPY9 
MFCD00057445 
Literature

Title: In vitro and in vivo efficacy of fluorodeoxycytidine analogs against highly pathogenic avian influenza H5N1, seasonal, and pandemic H1N1 virus infections.

Journal: Antiviral research 20111101

Title: Synthesis and anti-HCV activity of 3',4'-oxetane nucleosides.

Journal: Bioorganic & medicinal chemistry letters 20100801

Title: Simultaneous quantification of 2',2'-difluorodeoxycytidine and 2',2'-difluorodeoxyuridine nucleosides and nucleotides in white blood cells using porous graphitic carbon chromatography coupled with tandem mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20091001

Title: Design, synthesis, and antiviral properties of 4'-substituted ribonucleosides as inhibitors of hepatitis C virus replication: the discovery of R1479.

Journal: Bioorganic & medicinal chemistry letters 20070501

Title: Inhibition of hepatitis C replicon RNA synthesis by beta-D-2'-deoxy-2'-fluoro-2'-C-methylcytidine: a specific inhibitor of hepatitis C virus replication.

Journal: Antiviral chemistry & chemotherapy 20060101

Title: Design, synthesis, and antiviral activity of 2'-deoxy-2'-fluoro-2'-C-methylcytidine, a potent inhibitor of hepatitis C virus replication.

Journal: Journal of medicinal chemistry 20050825

Title: Synthesis and anti-viral activity of a series of d- and l-2'-deoxy-2'-fluororibonucleosides in the subgenomic HCV replicon system.

Journal: Bioorganic & medicinal chemistry 20050301

Title: Synthesis of some 2'-fluoro-2'-deoxy-3'-C-ethynyl and 3'-C-vinyl-beta-D-lyxofuranosyl nucleosides.

Journal: Nucleosides, nucleotides & nucleic acids 20050101

Title: Inhibition of the subgenomic hepatitis C virus replicon in huh-7 cells by 2'-deoxy-2'-fluorocytidine.

Journal: Antimicrobial agents and chemotherapy 20040201

Title: Measurement of the anti-cancer agent gemcitabine in human plasma by high-performance liquid chromatography.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030225

Title: A new class of Spiegelmers containing 2'-fluoro-nucleotides.

Journal: Nucleosides, nucleotides & nucleic acids 20030101

Title: Quantification of 2'-fluoro-2'-deoxyuridine and 2'-fluoro-2'-deoxycytidine in DNA and RNA isolated from rats and woodchucks using LC/MS/MS.

Journal: Chemical research in toxicology 20020701

Title: Nucleosides. 110. Synthesis and antiherpes virus activity of some 2'-fluoro-2'-deoxyarabinofuranosylpyrimidine nucleosides.

Journal: Journal of medicinal chemistry 19790101

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Additional Info:
Q & A