Home Other Building Blocks 10299-44-2
10299-44-2,MFCD01631207
Catalog No.:AA00863F

10299-44-2 | 8-AZAADENOSINE

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Purity
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1mg
≥98%
in stock  
$46.00   $32.00
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5mg
≥98%
in stock  
$133.00   $93.00
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10mg
≥98%
in stock  
$199.00   $139.00
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25mg
≥98%
in stock  
$382.00   $267.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00863F
Chemical Name:
8-AZAADENOSINE
CAS Number:
10299-44-2
Molecular Formula:
C9H12N6O4
Molecular Weight:
268.2294
MDL Number:
MFCD01631207
SMILES:
OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1nnc2c1ncnc2N
Properties
Computed Properties
 
Complexity:
336  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
2  
XLogP3:
-2.2  

Downstream Synthesis Route

[1]Davoll[JournaloftheChemicalSociety,1958,p.1593,1597]

[1]Veliz,EduardoA.;Easterwood,LaHomaM.;Beal,PeterA.[JournaloftheAmericanChemicalSociety,2003,vol.125,#36,p.10867-10876]

[2]Davoll[JournaloftheChemicalSociety,1958,p.1593,1597]

[1]Davoll[JournaloftheChemicalSociety,1958,p.1593,1597]

[1]Biagi;Giorgi;Livi;Scartoni;Lucacchini[IlFarmaco,1992,vol.47,#12,p.1457-1476]

[1]Nair;Chamberlain[Synthesis,1984,vol.NO.5,#5,p.401-403]

Literature

Title: The pH dependence of hairpin ribozyme catalysis reflects ionization of an active site adenine.

Journal: The Journal of biological chemistry 20110520

Title: Maria Anna Zipeto, et al. ADAR1 Activation Drives Leukemia Stem Cell Self-Renewal by Impairing Let-7 Biogenesis. Cell Stem Cell. 2016 Aug 4;19(2):177-191.

Title: Julia Ramírez-Moya, et al. ADAR1-mediated RNA editing is a novel oncogenic process in thyroid cancer and regulates miR-200 activity. Oncogene. 2020 Apr;39(18):3738-3753.

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SDS
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