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Home Other Building Blocks 1032823-75-8
1032823-75-8,MFCD18385004
Catalog No.:AA008TDV

1032823-75-8 | GSK1292263

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98+%
in stock  
$18.00   $13.00
- +
5mg
98+%
in stock  
$45.00   $32.00
- +
10mg
98+%
in stock  
$67.00   $47.00
- +
50mg
98+%
in stock  
$181.00   $127.00
- +
100mg
98+%
in stock  
$298.00   $209.00
- +
250mg
90%
in stock  
$728.00   $510.00
- +
500mg
90%
in stock  
$1,300.00   $910.00
- +
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA008TDV
Chemical Name:
GSK1292263
CAS Number:
1032823-75-8
Molecular Formula:
C23H28N4O4S
Molecular Weight:
456.5578
MDL Number:
MFCD18385004
SMILES:
CC(c1noc(n1)N1CCC(CC1)COc1ccc(nc1)c1ccc(cc1)S(=O)(=O)C)C
Properties
Computed Properties
 
Complexity:
685  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
32  
Hydrogen Bond Acceptor Count:
8  
Rotatable Bond Count:
7  
XLogP3:
4  

Upstream Synthesis Route

[1]Patent:US2010/29650,2010,A1,.Locationinpatent:Page/Pagecolumn50

[1]Patent:US2010/29650,2010,A1,.Locationinpatent:Page/Pagecolumn82

[1]OrganicProcessResearchandDevelopment,2016,vol.20,#8,p.1469-1475

[1]OrganicProcessResearchandDevelopment,2016,vol.20,#8,p.1469-1475

Downstream Synthesis Route

[1]Patent:US2010/29650,2010,A1.Locationinpatent:Page/Pagecolumn82

[1]Patent:US2010/29650,2010,A1.Locationinpatent:Page/Pagecolumn50

[1]Patent:US2010/29650,2010,A1.Locationinpatent:Page/Pagecolumn82

[1]OrganicProcessResearchandDevelopment,2016,vol.20,p.1469-1475

Literature

Title: X. Zhu, et al. GPR119 Agonists: A Novel Strategy for Type 2 Diabetes Treatment.

Title: Koji Matsumoto, et al. DS-8500a, an Orally Available G Protein-Coupled Receptor 119 Agonist, Upregulates Glucagon-Like Peptide-1 and Enhances Glucose-Dependent Insulin Secretion and Improves Glucose Homeostasis in Type 2 Diabetic Rats. J Pharmacol Exp Ther. 2018 Dec;367(3):509-517.

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SDS
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Tags:1032823-75-8 Molecular Formula|1032823-75-8 MDL|1032823-75-8 SMILES|1032823-75-8 GSK1292263