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104162-48-3,MFCD00145456
Catalog No.:AA003S4C

104162-48-3 | N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium

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5mg
≥95%
in stock  
$42.00   $29.00
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10mg
≥95%
in stock  
$79.00   $55.00
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100mg
95%
in stock  
$132.00   $93.00
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250mg
95%
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$256.00   $180.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003S4C
Chemical Name:
N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium
CAS Number:
104162-48-3
Molecular Formula:
C42H84ClNO2
Molecular Weight:
670.5749
MDL Number:
MFCD00145456
SMILES:
CCCCCCCC/C=C\CCCCCCCCOCC(C[N+](C)(C)C)OCCCCCCCC/C=C\CCCCCCCC.[Cl-]
Properties
Properties
 
Form:
Solid  
MP:
35-38°C  
Storage:
-20 ℃;  

Computed Properties
 
Complexity:
608  
Covalently-Bonded Unit Count:
2  
Defined Bond Stereocenter Count:
2  
Heavy Atom Count:
46  
Hydrogen Bond Acceptor Count:
3  
Rotatable Bond Count:
37  
Undefined Atom Stereocenter Count:
1  

Literature

Title: Properties, solution state behavior, and crystal structures of chelates of DOTMA.

Journal: Inorganic chemistry 20110905

Title: Brain temperature by Biosensor Imaging of Redundant Deviation in Shifts (BIRDS): comparison between TmDOTP5- and TmDOTMA-.

Journal: NMR in biomedicine 20100401

Title: Chondroitin sulfate capsule system for efficient and secure gene delivery.

Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20100101

Title: Pulmonary gene delivery of hybrid vector, lipopolyplex containing N-lauroylsarcosine, via the systemic route.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20090619

Title: Evaluation of proinflammatory cytokine production and liver injury induced by plasmid DNA/cationic liposome complexes with various mixing ratios in mice.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20090201

Title: Cationic liposomes-mediated plasmid DNA delivery in murine hepatitis induced by carbon tetrachloride.

Journal: Journal of liposome research 20090101

Title: Hybrid vector including polyethylenimine and cationic lipid, DOTMA, for gene delivery.

Journal: International journal of pharmaceutics 20081103

Title: Structure-activity investigation on the gene transfection properties of cardiolipin mimicking gemini lipid analogues.

Journal: Bioconjugate chemistry 20080601

Title: Efficient peritoneal dissemination treatment obtained by an immunostimulatory phosphorothioate-type CpG DNA/cationic liposome complex in mice.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20080320

Title: Exploitation of De Novo helper-lipids for effective gene delivery.

Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20080101

Title: Effect of spacer attachment sites and pH-sensitive headgroup expansion on cationic lipid-mediated gene delivery of three novel myristoyl derivatives.

Journal: Biophysical chemistry 20070901

Title: Cationic transfersomes based topical genetic vaccine against hepatitis B.

Journal: International journal of pharmaceutics 20070801

Title: Inhibition of peritoneal dissemination of tumor cells by single dosing of phosphodiester CpG oligonucleotide/cationic liposome complex.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20061010

Title: Physicochemical and pharmacokinetic characteristics of cationic liposomes.

Journal: Die Pharmazie 20060201

Title: Use of lipoplex-induced nuclear factor-kappaB activation to enhance transgene expression by lipoplex in mouse lung.

Journal: The journal of gene medicine 20060101

Title: Noninvasive MR thermometry using paramagnetic lanthanide complexes of 1,4,7,10-tetraazacyclodoecane-alpha,alpha',alpha'',alpha'''-tetramethyl-1,4,7,10-tetraacetic acid (DOTMA4-).

Journal: Magnetic resonance in medicine 20050201

Title: Liposomal transfection of squamous carcinoma cells of the head and neck with IL-2 and B7 plasmids inducing an autologous immune response in vitro.

Journal: Anticancer research 20050101

Title: Synthesis, characterization and transfection activity of new saturated and unsaturated cationic lipids.

Journal: Farmaco (Societa chimica italiana : 1989) 20041101

Title: In vivo gene transfection via intravitreal injection of cationic liposome/plasmid DNA complexes in rabbits.

Journal: International journal of pharmaceutics 20040708

Title: New cationic lipids for gene transfer with high efficiency and low toxicity: T-shape cholesterol ester derivatives.

Journal: Bioorganic & medicinal chemistry letters 20040517

Title: Peptide-mediated gene transfer of cationic lipid/plasmid DNA complexes to endothelial cells.

Journal: Journal of drug targeting 20040501

Title: Asymmetric synthesis of dialkyloxy-3-alkylammonium cationic lipids.

Journal: The Journal of organic chemistry 20040206

Title: Analysis of hepatic disposition of galactosylated cationic liposome/plasmid DNA complexes in perfused rat liver.

Journal: Pharmaceutical research 20030901

Title: Transfection with fluorinated lipoplexes based on fluorinated analogues of DOTMA, DMRIE and DPPES.

Journal: Biochimica et biophysica acta 20020831

Title: Effects of erythrocytes and serum proteins on lung accumulation of lipoplexes containing cholesterol or DOPE as a helper lipid in the single-pass rat lung perfusion system.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20010901

Title: Interaction between DNA-cationic liposome complexes and erythrocytes is an important factor in systemic gene transfer via the intravenous route in mice: the role of the neutral helper lipid.

Journal: Gene therapy 20010501

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Tags:104162-48-3 Molecular Formula|104162-48-3 MDL|104162-48-3 SMILES|104162-48-3 N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium