Home Carboxes 1078-61-1
1078-61-1,MFCD00002776
Catalog No.:AA003HYZ
1078-61-1 | 3-(3,4-Dihydroxyphenyl)propanoic acid
Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
95%
1 week  
$79.00   $55.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Q & A
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003HYZ
Chemical Name:
3-(3,4-Dihydroxyphenyl)propanoic acid
CAS Number:
1078-61-1
Molecular Formula:
C9H10O4
Molecular Weight:
182.1733
MDL Number:
MFCD00002776
IUPAC Name:
3-(3,4-dihydroxyphenyl)propanoic acid
InChI:
InChI=1S/C9H10O4/c10-7-3-1-6(5-8(7)11)2-4-9(12)13/h1,3,5,10-11H,2,4H2,(H,12,13)
InChI Key:
DZAUWHJDUNRCTF-UHFFFAOYSA-N
SMILES:
OC(=O)CCc1ccc(c(c1)O)O
EC Number:
214-083-8
UNII:
MSW0228VUB
Properties
Computed Properties
 
Complexity:
181  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
182.058g/mol
Formal Charge:
0
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
182.175g/mol
Monoisotopic Mass:
182.058g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
77.8A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.5  

Synonyms
 
3,4-dihydroxyhydrocinnamic acid 
3,4-dihydroxyphenylpropionic acid 
3-(3,4-Dihydroxyphenyl)propanoic acid 
2H-Pyrimido[1,2-a]pyrimidine,1,3,4,6,7,8-hexahydro-1-methyl- 
DHC 
Benzenepropanoic acid, 3,4-dihydroxy- 
Hydrocaffeic acid polymer 
3,4-Dihydroxybenzenepropanoic acid 
HYKOP 
3,4-Dihydroxybenzenepropionic acid 
3,4-dihydroxyhydrocinnamate 
CHEBI:48400 
3,4-Dihydroxydihydrocinnamic acid 
DZAUWHJDUNRCTF-UHFFFAOYSA-N 
3,4-dihydroxyphenylpropionic acid, potassium salt 
Hydrocaffeate 
MFCD00002776 
NSC624007 
71693-95-3 
3,4-Dihydroxy-beta-phenylpropionic acid 
3,4-Dihydroxyphenylpropanoate 
Dihydrocafeate 
Dihydrocaffeate 
zlchem 1078 
ACMC-1BOYJ 
3-(3,4-dihydroxyphenyl)propionic acid 
bmse000680 
AC1L88XM 
3,4-Dihydroxydihydrocinnamate 
3,4-Dihydroxyphenylpropionate 
SCHEMBL245530 
3,4-Dihydroxybenzenepropionate 
CHEMBL136927 
cid_348154 
Hydrocinnamic acid,4-dihydroxy- 
3,4-dihydroxybenzenepropanoicacid 
dihydrocaffeic acid 
BDBM41957 
CTK0H6944 
3,4-Dihydroxy-b-phenylpropionate 
3,4-dihydroxy-benzenepropanoicaci 
3,4-dihydroxyhydro cinnamic acid 
3,4-HPA 
DTXSID40221919 
ZLD0544 
ZINC388044 
3-(3,4-Dihydroxyphenyl)propionate 
Dihydrocaffeic acid 
AC1Q7586 
KS-00000WJ3 
3,4-Dihydroxy-beta-phenylpropionate 
BBL027403 
NSC407275 
SBB068270 
STL377912 
3,4-Dihydroxy-b-phenylpropionic acid 
AKOS015856196 
3,4-Dihydroxyhydrocinnamic acid, 98% 
1078-61-1 
MCULE-4912045197 
NSC-407275 
NSC-624007 
RP24319 
3-(3,4-dihydroxy-phenyl)-propionic acid 
AK305409 
SC-25524 
ST088603 
3-(3,4-Dihydroxyphenyl)propanoic acid # 
beta-(3,4-dihydroxyphenyl) propionic acid 
3-(3,4-Dihydroxyphenyl)propionic acid 
3-[3,4-bis(oxidanyl)phenyl]propanoic acid 
DB-040792 
TC-066391 
FT-0613602 
3,4-dihydroxy-(6CI,7CI,8CI)Hydrocinnamate 
3-(3,4-DIHYDROXYPHENYL)PROPIONICACID 
C10447 
3,4-dihydroxy-(6CI,7CI,8CI)Hydrocinnamic acid 
I14-5755 
J-510568 
Hydrocaffeic acid 
BF0C7A6D-A5FC-4B39-819E-5ECC037C0C39 
InChI=1/C9H10O4/c10-7-3-1-6(5-8(7)11)2-4-9(12)13/h1,3,5,10-11H,2,4H2,(H,12,13 
caffeic acid 
3,4-Dihydroxyphenylpropionic acid 
3,4-dihydrocaffeic acid 
UNII-MSW0228VUB 
MSW0228VUB 
Hydrocinnamic acid, 3,4-dihydroxy- 
3-(3,4-dihydroxyphenyl)propanoate 
Benzenepropanoic acid,4-dihydroxy- 
3,4-Dihydroxyhydrocinnamic acid 
NSC 624007 
EINECS 214-083-8 
C9-H10-O4 
CID348154 
ACN-031367 
NSC 407275 
BRN 2213449 
3,4-dihydroxyphenylpropionic acid, potassium salt 
3-10-00-01517 (Beilstein Handbook Reference) 
C000995 
Literature

Title: Mollusk glue inspired mucoadhesives for biomedical applications.

Journal: Langmuir : the ACS journal of surfaces and colloids 20121002

Title: Structure-anti-leukemic activity relationship study of ortho-dihydroxycoumarins in U-937 cells: key role of the δ-lactone ring in determining differentiation-inducing potency and selective pro-apoptotic action.

Journal: Bioorganic & medicinal chemistry 20120915

Title: Hypolipidemic and antioxidant effects of hydroxycinnamic acids, quercetin, and cyanidin 3-glucoside in hypercholesterolemic erythrocytes (in vitro study).

Journal: European journal of nutrition 20120601

Title: Influence of coffee roasting on the incorporation of phenolic compounds into melanoidins and their relationship with antioxidant activity of the brew.

Journal: Journal of agricultural and food chemistry 20120502

Title: Proteogenomic evidence for β-oxidation of plant-derived 3-phenylpropanoids in 'Aromatoleum aromaticum' EbN1.

Journal: Proteomics 20120501

Title: New losartan-hydrocaffeic acid hybrids as antihypertensive-antioxidant dual drugs: Ester, amide and amine linkers.

Journal: European journal of medicinal chemistry 20120401

Title: Differential effects of environment on potato phenylpropanoid and carotenoid expression.

Journal: BMC plant biology 20120101

Title: Multiple tyrosine metabolites are GPR35 agonists.

Journal: Scientific reports 20120101

Title: Coffee components inhibit amyloid formation of human islet amyloid polypeptide in vitro: possible link between coffee consumption and diabetes mellitus.

Journal: Journal of agricultural and food chemistry 20111228

Title: Enzymatically degradable mussel-inspired adhesive hydrogel.

Journal: Biomacromolecules 20111212

Title: Toxicological aspects of the use of phenolic compounds in disease prevention.

Journal: Interdisciplinary toxicology 20111201

Title: A seven-transmembrane receptor that mediates avoidance response to dihydrocaffeic acid, a water-soluble repellent in Caenorhabditis elegans.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20111116

Title: Identification of novel circulating coffee metabolites in human plasma by liquid chromatography-mass spectrometry.

Journal: Journal of chromatography. A 20110722

Title: Evaluation of allergens in propolis by ultra-performance liquid chromatography/tandem mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20110615

Title: Antiglycative and neuroprotective activity of colon-derived polyphenol catabolites.

Journal: Molecular nutrition & food research 20110501

Title: Improved enzymatic production of phenolated acylglycerols through alkyl phenolate intermediates.

Journal: Biotechnology letters 20110401

Title: Contribution of cinnamic acid analogues in rosmarinic acid to inhibition of snake venom induced hemorrhage.

Journal: Bioorganic & medicinal chemistry 20110401

Title: Deglycosylation of puerarin and other aromatic C-glucosides by a newly isolated human intestinal bacterium.

Journal: Environmental microbiology 20110201

Title: Impact of polyphenol metabolites produced by colonic microbiota on expression of COX-2 and GSTT2 in human colon cells (LT97).

Journal: Nutrition and cancer 20110101

Title: Phenylpropanoid glycoside analogues: enzymatic synthesis, antioxidant activity and theoretical study of their free radical scavenger mechanism.

Journal: PloS one 20110101

Title: Kinetic cooperativity of tyrosinase. A general mechanism.

Journal: Acta biochimica Polonica 20110101

Title: Production of chlorogenic acid in Varthemia persica DC (var. persica) callus cultures.

Journal: Research in pharmaceutical sciences 20110101

Title: Plasma appearance and correlation between coffee and green tea metabolites in human subjects.

Journal: The British journal of nutrition 20101201

Title: Does conjugation of antioxidants improve their antioxidative/anti-inflammatory potential?

Journal: Bioorganic & medicinal chemistry 20101201

Title: First synthesis, characterization, and evidence for the presence of hydroxycinnamic acid sulfate and glucuronide conjugates in human biological fluids as a result of coffee consumption.

Journal: Organic & biomolecular chemistry 20101121

Title: In vitro and in vivo conjugation of dietary hydroxycinnamic acids by UDP-glucuronosyltransferases and sulfotransferases in humans.

Journal: The Journal of nutritional biochemistry 20101101

Title: Biochemical mechanism of caffeic acid phenylethyl ester (CAPE) selective toxicity towards melanoma cell lines.

Journal: Chemico-biological interactions 20101006

Title: Colonic metabolites of berry polyphenols: the missing link to biological activity?

Journal: The British journal of nutrition 20101001

Title: Comparison of hesperetin and its metabolites for cholesterol-lowering and antioxidative efficacy in hypercholesterolemic hamsters.

Journal: Journal of medicinal food 20100801

Title: Bioavailability of coffee chlorogenic acids and green tea flavan-3-ols.

Journal: Nutrients 20100801

Title: Flavanols and anthocyanins in cardiovascular health: a review of current evidence.

Journal: International journal of molecular sciences 20100101

Title: Bioactive dehydrotyrosyl and dehydrodopyl compounds of marine origin.

Journal: Marine drugs 20100101

Title: Quantitative analysis of plasma caffeic and ferulic acid equivalents by liquid chromatography tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091201

Title: Losartan-antioxidant hybrids: novel molecules for the prevention of hypertension-induced cardiovascular damage.

Journal: Journal of medicinal chemistry 20091126

Title: Coordination chemistry based approach to lipophilic inhibitors of 1-deoxy-D-xylulose-5-phosphate reductoisomerase.

Journal: Journal of medicinal chemistry 20091112

Title: Kukoamine A analogs with lipoxygenase inhibitory activity.

Journal: Journal of enzyme inhibition and medicinal chemistry 20091001

Title: Metabolite profiling of hydroxycinnamate derivatives in plasma and urine after the ingestion of coffee by humans: identification of biomarkers of coffee consumption.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20090801

Title: Molecular modifications on carboxylic acid derivatives as potent histone deacetylase inhibitors: Activity and docking studies.

Journal: Bioorganic & medicinal chemistry 20090715

Title: Dihydroxylated phenolic acids derived from microbial metabolism reduce lipopolysaccharide-stimulated cytokine secretion by human peripheral blood mononuclear cells.

Journal: The British journal of nutrition 20090701

Title: Production of o-diphenols by immobilized mushroom tyrosinase.

Journal: Journal of biotechnology 20090115

Title: Luteal blood flow and luteal function.

Journal: Journal of ovarian research 20090101

Title: Analysis of urinary aromatic acids by liquid chromatography tandem mass spectrometry.

Journal: Biomedical chromatography : BMC 20081201

Title: Clinical applications of urinary organic acids. Part 2. Dysbiosis markers.

Journal: Alternative medicine review : a journal of clinical therapeutic 20081201

Title: Biochemical characterization of L-DOPA 2,3-dioxygenase, a single-domain type I extradiol dioxygenase from lincomycin biosynthesis.

Journal: Archives of biochemistry and biophysics 20081115

Title: Antioxidant activity of a combinatorial library of emulsifier-antioxidant bioconjugates.

Journal: Journal of agricultural and food chemistry 20081008

Title: Effect of dihydrocaffeic acid on UV irradiation of human keratinocyte HaCaT cells.

Journal: Archives of biochemistry and biophysics 20080815

Title: Synthesis of bis, tris and tetra(dihydrocaffeoyl)polyamine conjugates as antibacterial agents against VRSA.

Journal: Archives of pharmacal research 20080601

Title: Investigation of the metabolic fate of dihydrocaffeic acid.

Journal: Biochemical pharmacology 20080301

Title: Kinetics and mechanism of the reaction between chromium(III) and 3,4-dihydroxy-phenyl-propenoic acid (caffeic acid) in weak acidic aqueous solutions.

Journal: Bioinorganic chemistry and applications 20080101

Title: Engineering and Applications of fungal laccases for organic synthesis.

Journal: Microbial cell factories 20080101

Title: Reaction of chromium(III) with 3,4-dihydroxybenzoic acid: kinetics and mechanism in weak acidic aqueous solutions.

Journal: Bioinorganic chemistry and applications 20080101

Title: Biologically active natural products from Mongolian medicinal plants Scorzonera divaricata and Scorzonera pseudodivaricata.

Journal: Journal of natural products 20070601

Title: Weakening of salmonella with selected microbial metabolites of berry-derived phenolic compounds and organic acids.

Journal: Journal of agricultural and food chemistry 20070516

Title: Absorption and metabolism of bioactive molecules after oral consumption of cooked edible heads of Cynara scolymus L. (cultivar Violetto di Provenza) in human subjects: a pilot study.

Journal: The British journal of nutrition 20070501

Title: Ferric-reducing ability power of selected plant polyphenols and their metabolites: implications for clinical studies on the antioxidant effects of fruits and vegetable consumption.

Journal: Basic & clinical pharmacology & toxicology 20070501

Title: Metabolism of flavone C-glucosides and p-coumaric acid from antioxidant of bamboo leaves (AOB) in rats.

Journal: The British journal of nutrition 20070301

Title: Identification of free radical species derived from caffeic acid and related polyphenols.

Journal: Free radical research 20070101

Title: Catabolism of L-phenylalanine and L-tyrosine by Rhodobacter sphaeroides OU5 occurs through 3,4-dihydroxyphenylalanine.

Journal: Research in microbiology 20070101

Title: Lipase-catalyzed transesterification of dihydrocaffeic acid with flaxseed oil for the synthesis of phenolic lipids.

Journal: Journal of biotechnology 20061215

Title: Naphthalenemethyl ester derivative of dihydroxyhydrocinnamic acid, a component of cinnamon, increases glucose disposal by enhancing translocation of glucose transporter 4.

Journal: Diabetologia 20061001

Title: The feruloyl esterase system of Talaromyces stipitatus: determining the hydrolytic and synthetic specificity of TsFaeC.

Journal: Journal of biotechnology 20060901

Title: Calculating molar absorptivities for quinones: application to the measurement of tyrosinase activity.

Journal: Analytical biochemistry 20060401

Title: Immunosensors for pollutants working in organic media. Study of performances of different tracers with luminescent detection.

Journal: Analytical and bioanalytical chemistry 20060401

Title: Antioxidant profile of dihydroxy- and trihydroxyphenolic acids--a structure-activity relationship study.

Journal: Free radical research 20060401

Title: Phenolic profile of Asturian (Spain) natural cider.

Journal: Journal of agricultural and food chemistry 20060111

Title: Lipase-catalyzed esterification of selected phenolic acids with linolenyl alcohols in organic solvent media.

Journal: Applied biochemistry and biotechnology 20051001

Title: Potentiometric studies on the complexation of copper(II) by phenolic acids as discrete ligand models of humic substances.

Journal: Talanta 20050430

Title: Human fecal water content of phenolics: the extent of colonic exposure to aromatic compounds.

Journal: Free radical biology & medicine 20050315

Title: Degradation of neohesperidin dihydrochalcone by human intestinal bacteria.

Journal: Journal of agricultural and food chemistry 20050309

Title: Antioxidant activity of olive phenols: mechanistic investigation and characterization of oxidation products by mass spectrometry.

Journal: Organic & biomolecular chemistry 20050207

Title: Bioavailability and pharmacokinetics of caffeoylquinic acids and flavonoids after oral administration of Artichoke leaf extracts in humans.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20050101

Title: Antioxidant effects of dihydrocaffeic acid in human EA.hy926 endothelial cells.

Journal: The Journal of nutritional biochemistry 20041201

Title: Effects of chlorogenic acid and its metabolites on the sleep-wakefulness cycle in rats.

Journal: European journal of pharmacology 20041119

Title: Microbial metabolites of ingested caffeic acid are absorbed by the monocarboxylic acid transporter (MCT) in intestinal Caco-2 cell monolayers.

Journal: Journal of agricultural and food chemistry 20041020

Title: Potentiometric and spectroscopic studies on aluminium(III) complexes of some catechol derivatives.

Journal: Chemical & pharmaceutical bulletin 20040801

Title: Enzymatic grafting of carboxyl groups on to chitosan--to confer on chitosan the property of a cationic dye adsorbent.

Journal: Bioresource technology 20040101

Title: Kinetics and mechanism of the reaction between chromium(III) and 3,4-dihydroxyphenylpropionic (dihydrocaffeic) acid in weak acidic aqueous solutions.

Journal: Journal of inorganic biochemistry 20040101

Title: Pulse radiolysis, electron paramagnetic resonance spectroscopy and theoretical calculations of caffeic acid oligomer radicals.

Journal: Biochimica et biophysica acta 20030317

Title: Organic and inorganic substrates as probes for comparing native bovine lactoperoxidase and recombinant human myeloperoxidase.

Journal: Journal of inorganic biochemistry 20030201

Title: Laccase-catalysed synthesis of coupling products of phenolic substrates in different reactors.

Journal: Applied microbiology and biotechnology 20030201

Title: Lipid-lowering efficacy of hesperetin metabolites in high-cholesterol fed rats.

Journal: Clinica chimica acta; international journal of clinical chemistry 20030101

Title: Zymography of monophenolase and o-diphenolase activities of polyphenol oxidase.

Journal: Analytical biochemistry 20020715

Title: An enantioselective synthesis of tarchonanthuslactone.

Journal: The Journal of organic chemistry 20020419

Title: L-tyrosine-based backbone-modified poly(amino acids).

Journal: Journal of biomaterials science. Polymer edition 20020101

Title: Caffeic acid, chlorogenic acid, and dihydrocaffeic acid metabolism: glutathione conjugate formation.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20011101

Title: Plant catechols prevent lipid peroxidation in human plasma and erythrocytes.

Journal: Molecular and cellular biochemistry 20011001

Title: Degradation of natural polyphenols by methanogenic consortia enriched from digested municipal sludge.

Journal: Water research 20010801

Title: Properties of diphenolase from Vanilla planifolia (Andr.) shoot primordia cultured in vitro.

Journal: Journal of agricultural and food chemistry 20010701

Title: Phenolic acid amides of phenolic benzylamines against UVA-induced oxidative stress in skin.

Journal: International journal of cosmetic science 20010201

Title: Mechanism of toxicity of esters of caffeic and dihydrocaffeic acids.

Journal: Bioorganic & medicinal chemistry 20010101

Title: Hydrogen peroxide supports hepatocyte P450 catalysed xenobiotic/drug metabolic activation to form cytotoxic reactive intermediates.

Journal: Advances in experimental medicine and biology 20010101

Title: Selective inhibitory activity of polyhydroxycarboxylates derived from phenolic compounds against human immunodeficiency virus replication.

Journal: Journal of acquired immune deficiency syndromes 19910101

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Additional Info:
Q & A