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108238-41-1,MFCD00143082
Catalog No.:AA003INQ

108238-41-1 | 3,6-Dihydroxy-2-phenyl-4H-chromen-4-one

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5mg
95%
in stock  
$65.00   $45.00
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250mg
98%
in stock  
$86.00   $60.00
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1g
>98.0%(HPLC)
in stock  
$87.00   $61.00
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5g
98%
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$315.00   $220.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003INQ
Chemical Name:
3,6-Dihydroxy-2-phenyl-4H-chromen-4-one
CAS Number:
108238-41-1
Molecular Formula:
C15H10O4
Molecular Weight:
254.2375
MDL Number:
MFCD00143082
SMILES:
Oc1ccc2c(c1)c(=O)c(c(o2)c1ccccc1)O
Properties
Properties
 
Form:
Solid  

Computed Properties
 
Complexity:
395  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
1  
XLogP3:
3  

Downstream Synthesis Route

[1]Row;Rao[CurrentScience,1956,vol.25,p.393]Vyas;Shah[Proceedings-IndianAcademyofSciences,SectionA,1950,#32,p.386,387]

[1]Row;Rao[CurrentScience,1956,vol.25,p.393]

[1]Row;Rao[CurrentScience,1956,vol.25,p.393]

108238-41-1   
3,6-Dihydroxyflavothione 

[1]Elisei,Fausto;Lima,JoaoC.;Ortica,Fausto;Aloisi,GianG.;Costa,Manuela;Leitao,Emilia;Abreu,Isabel;Dias,Antonio;Bonifacio,Vasco;Medeiros,Jorge;Macanita,AntonioL.;Becker,RalphS.[JournalofPhysicalChemistryA,2000,vol.104,#25,p.6095-6102]

Literature

Title: Small molecule inhibitors of the HPV16-E6 interaction with caspase 8.

Journal: Bioorganic & medicinal chemistry letters 20120301

Title: Interference of selected flavonoid aglycons in platelet aggregation assays.

Journal: Clinical chemistry and laboratory medicine 20120227

Title: Curcumin induces the apoptosis of human monocytic leukemia THP-1 cells via the activation of JNK/ERK pathways.

Journal: BMC complementary and alternative medicine 20120101

Title: MicroRNA-34a and microRNA-21 play roles in the chemopreventive effects of 3,6-dihydroxyflavone on 1-methyl-1-nitrosourea-induced breast carcinogenesis.

Journal: Breast cancer research : BCR 20120101

Title: Flavonoids in prevention of diseases with respect to modulation of Ca-pump function.

Journal: Interdisciplinary toxicology 20110901

Title: Quercetin-iron chelates are transported via glucose transporters.

Journal: Free radical biology & medicine 20110415

Title: Evaluation of antiaggregatory activity of flavonoid aglycone series.

Journal: Nutrition journal 20110101

Title: 3,6-Dihydroxyflavone induces apoptosis in leukemia HL-60 cell via reactive oxygen species-mediated p38 MAPK/JNK pathway.

Journal: European journal of pharmacology 20101201

Title: Cytotoxic flavonoids as agonists of peroxisome proliferator-activated receptor gamma on human cervical and prostate cancer cells.

Journal: Journal of natural products 20100723

Title: Reliability of bond dissociation enthalpy calculated by the PM6 method and experimental TEAC values in antiradical QSAR of flavonoids.

Journal: Bioorganic & medicinal chemistry 20100101

Title: Effect of flavonoids on androgen and glucocorticoid receptors based on in vitro reporter gene assay.

Journal: Bioorganic & medicinal chemistry letters 20090815

Title: Antimicrobial natural products as beta-ketoacyl-acyl carrier protein synthase III inhibitors.

Journal: Bioorganic & medicinal chemistry 20090801

Title: Inhibition of the sarcoplasmic/endoplasmic reticulum Ca2+-ATPase by flavonoids: a quantitative structure-activity relationship study.

Journal: IUBMB life 20081201

Title: Structurally related cytotoxic effects of flavonoids on human cancer cells in vitro.

Journal: Archives of pharmacal research 20080901

Title: Structure-activity relationship studies of flavonoids as potent inhibitors of human platelet 12-hLO, reticulocyte 15-hLO-1, and prostate epithelial 15-hLO-2.

Journal: Bioorganic & medicinal chemistry 20071201

Title: Inhibition of Plasmodium falciparum fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids.

Journal: Journal of medicinal chemistry 20060601

Title: Glucosylation of phenolic compounds by Pharbitis nil hairy roots: I. Glucosylation of coumarin and flavone derivatives.

Journal: Bioscience, biotechnology, and biochemistry 20041001

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SDS
Tags:108238-41-1 Molecular Formula|108238-41-1 MDL|108238-41-1 SMILES|108238-41-1 3,6-Dihydroxy-2-phenyl-4H-chromen-4-one