Title: Promotion of SIRT1 protein degradation and lower SIRT1 gene expression via reactive oxygen species is involved in Sb-induced apoptosis in BEAS-2b cells.
Journal: Toxicology letters 20181015
Title: Perfluorobutanesulfonic acid (PFBS) potentiates adipogenesis of 3T3-L1 adipocytes.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20181001
Title: Perfluorooctanoic acid stimulates ovarian cancer cell migration, invasion via ERK/NF-κB/MMP-2/-9 pathway.
Journal: Toxicology letters 20180915
Title: Glyphosate induces growth of estrogen receptor alpha positive cholangiocarcinoma cells via non-genomic estrogen receptor/ERK1/2 signaling pathway.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20180801
Title: Bisphenol A affects trophoblast invasion by inhibiting CXCL8 expression in decidual stromal cells.
Journal: Molecular and cellular endocrinology 20180715
Title: Synergistic action of the nephrotoxic mycotoxins ochratoxin A and citrinin at nanomolar concentrations in human proximal tubule-derived cells.
Journal: Toxicology letters 20180701
Title: ROS generation and MAPKs activation contribute to the Ni-induced testosterone synthesis disturbance in rat Leydig cells.
Journal: Toxicology letters 20180615
Title: Benzo[a]pyrene activates an AhR/Src/ERK axis that contributes to CYP1A1 induction and stable DNA adducts formation in lung cells.
Journal: Toxicology letters 20180601
Title: Acrylamide-induced oxidative stress and inflammatory response are alleviated by N-acetylcysteine in PC12 cells: Involvement of the crosstalk between Nrf2 and NF-κB pathways regulated by MAPKs.
Journal: Toxicology letters 20180515
Title: Butyl paraben promotes apoptosis in human trophoblast cells through increased oxidative stress-induced endoplasmic reticulum stress.
Journal: Environmental toxicology 20180401
Title: Natural Polyphenol Chlorogenic Acid Protects Against Acetaminophen-Induced Hepatotoxicity by Activating ERK/Nrf2 Antioxidative Pathway.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20180301
Title: Cantharidic acid induces apoptosis through the p38 MAPK signaling pathway in human hepatocellular carcinoma.
Journal: Environmental toxicology 20180301
Title: Norcantharidin induce apoptosis in human nasopharyngeal carcinoma through caspase and mitochondrial pathway.
Journal: Environmental toxicology 20180301
Title: The excitotoxity of NMDA receptor NR2D subtype mediates human fetal lung fibroblasts proliferation and collagen production.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20180201
Title: Permethrin decreased insulin-stimulated AKT phosphorylation dependent on extracellular signal-regulated kinase-1 (ERK), but not AMP-activated protein kinase α (AMPKα), in C2C12 myotubes.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20171101
Title: Influence of aldose reductase on epithelial-to-mesenchymal transition signaling in lens epithelial cells.
Journal: Chemico-biological interactions 20171001
Title: Tussilagonone-induced Nrf2 pathway activation protects HepG2 cells from oxidative injury.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20171001
Title: The expression of keratin 6 is regulated by the activation of the ERK1/2 pathway in arsenite transformed human urothelial cells.
Journal: Toxicology and applied pharmacology 20170915
Title: Nimbolide induces apoptosis in human nasopharyngeal cancer cells.
Journal: Environmental toxicology 20170801
Title: The induction of cytochrome P450 2E1 by ethanol leads to the loss of synaptic proteins via PPARα down-regulation.
Journal: Toxicology 20170615
Title: Inhibitory effects of Leucaena leucocephala on the metastasis and invasion of human oral cancer cells.
Journal: Environmental toxicology 20170601
Title: Cadmium-induced IL-6 and IL-8 expression and release from astrocytes are mediated by MAPK and NF-κB pathways.
Journal: Neurotoxicology 20170501
Title: Triiodothyronine promotes the proliferation of epicardial progenitor cells through the MAPK/ERK pathway.
Journal: Biochemical and biophysical research communications 20170429
Title: Suppression of reactive oxygen species-mediated ERK and JNK activation sensitizes dihydromyricetin-induced mitochondrial apoptosis in human non-small cell lung cancer.
Journal: Environmental toxicology 20170401
Title: Dysregulation of MAP Kinase Signaling Pathways Including p38MAPK, SAPK/JNK, and ERK1/2 in Cultured Rat Cerebellar Astrocytes Exposed to Diphenylarsinic Acid.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20170401
Title: Vibrio cholerae Cholix Toxin-Induced HepG2 Cell Death is Enhanced by Tumor Necrosis Factor-Alpha Through ROS and Intracellular Signal-Regulated Kinases.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20170401
Title: Transglutaminase 2 is involved in amyloid-beta(1-42)-induced pro-inflammatory activation via AP1/JNK signalling pathways in THP-1 monocytes.
Journal: Amino acids 20170301
Title: Airborne fine particulate matter causes murine bronchial hyperreactivity via MAPK pathway-mediated M(3) muscarinic receptor upregulation.
Journal: Environmental toxicology 20170201
Title: Dibutyltin-induced alterations of interleukin 1beta secretion from human immune cells.
Journal: Journal of applied toxicology : JAT 20170201
Title: Activation of G protein-coupled receptor 30 by thiodiphenol promotes proliferation of estrogen receptor α-positive breast cancer cells.
Journal: Chemosphere 20170201
Title: mTOR inhibition by rapamycin protects against deltamethrin-induced apoptosis in PC12 Cells.
Journal: Environmental toxicology 20170101
Title: Role of AMP-activated protein kinase α1 in 17α-ethinylestradiol-induced cholestasis in rats.
Journal: Archives of toxicology 20170101
Title: Atg5-dependent autophagy plays a protective role against methylmercury-induced cytotoxicity.
Journal: Toxicology letters 20161116
Title: Gallic acid-capped gold nanoparticles inhibit EGF-induced MMP-9 expression through suppression of p300 stabilization and NFκB/c-Jun activation in breast cancer MDA-MB-231 cells.
Journal: Toxicology and applied pharmacology 20161101
Title: Neogambogic acid prevents silica-induced fibrosis via inhibition of high-mobility group box 1 and MCP-1-induced protein 1.
Journal: Toxicology and applied pharmacology 20161015
Title: Triazine herbicides inhibit relaxin signaling and disrupt nitric oxide homeostasis.
Journal: Toxicology and applied pharmacology 20160915
Title: Hepatocyte-protective effect of nectandrin B, a nutmeg lignan, against oxidative stress: Role of Nrf2 activation through ERK phosphorylation and AMPK-dependent inhibition of GSK-3β.
Journal: Toxicology and applied pharmacology 20160915
Title: Sodium arsenite inhibited genomic estrogen signaling but induced pERα (Ser118) via MAPK pathway in breast cancer cells.
Journal: Environmental toxicology 20160901
Title: 2,3,5,6-Tetramethylpyrazine (TMP) down-regulated arsenic-induced heme oxygenase-1 and ARS2 expression by inhibiting Nrf2, NF-κB, AP-1 and MAPK pathways in human proximal tubular cells.
Journal: Archives of toxicology 20160901
Title: Allopurinol induces innate immune responses through mitogen-activated protein kinase signaling pathways in HL-60 cells.
Journal: Journal of applied toxicology : JAT 20160901
Title: Alpha-naphthylisothiocyanate impairs bile acid homeostasis through AMPK-FXR pathways in rat primary hepatocytes.
Journal: Toxicology 20160831
Title: Inhibition of Macrophage CD36 Expression and Cellular Oxidized Low Density Lipoprotein (oxLDL) Accumulation by Tamoxifen: A PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR (PPAR)γ-DEPENDENT MECHANISM.
Journal: The Journal of biological chemistry 20160812
Title: The effects of MEK1/2 inhibition on cigarette smoke exposure-induced ET receptor upregulation in rat cerebral arteries.
Journal: Toxicology and applied pharmacology 20160801
Title: Benzo(a)pyrene inhibits migration and invasion of extravillous trophoblast HTR-8/SVneo cells via activation of the ERK and JNK pathway.
Journal: Journal of applied toxicology : JAT 20160701
Title: MicroRNA-21 activation of ERK signaling via PTEN is involved in arsenite-induced autophagy in human hepatic L-02 cells.
Journal: Toxicology letters 20160611
Title: Perfluorinated chemicals, PFOS and PFOA, enhance the estrogenic effects of 17β-estradiol in T47D human breast cancer cells.
Journal: Journal of applied toxicology : JAT 20160601
Title: Involvement of PI3K/Akt, ERK and p38 signaling pathways in emodin-mediated extrinsic and intrinsic human hepatoblastoma cell apoptosis.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20160601
Title: Gallic acid abolishes the EGFR/Src/Akt/Erk-mediated expression of matrix metalloproteinase-9 in MCF-7 breast cancer cells.
Journal: Chemico-biological interactions 20160525
Title: MCPIP1 Regulates Alveolar Macrophage Apoptosis and Pulmonary Fibroblast Activation After in vitro Exposure to Silica.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20160501
Title: Hydroquinone stimulates cell invasion through activator protein-1-dependent induction of MMP-9 in HepG2 human hepatoma cells.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20160301
Title: MAPK and SHH pathways modulate type 3 deiodinase expression in papillary thyroid carcinoma.
Journal: Endocrine-related cancer 20160301
Title: Erk-Creb pathway suppresses glutathione-S-transferase pi expression under basal and oxidative stress conditions in zebrafish embryos.
Journal: Toxicology letters 20160105
Title: Particulate matter phagocytosis induces tissue factor in differentiating macrophages.
Journal: Journal of applied toxicology : JAT 20160101
Title: PM2.5-induced oxidative stress increases adhesion molecules expression in human endothelial cells through the ERK/AKT/NF-κB-dependent pathway.
Journal: Journal of applied toxicology : JAT 20160101
Title: Dual inhibition of CDK4/Rb and PI3K/AKT/mTOR pathways by ON123300 induces synthetic lethality in mantle cell lymphomas.
Journal: Leukemia 20160101
Title: The Role of MAPK Pathways in Airborne Fine Particulate Matter-Induced Upregulation of Endothelin Receptors in Rat Basilar Arteries.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20160101
Title: The role of HO-1 in protection against lead-induced neurotoxicity.
Journal: Neurotoxicology 20160101
Title: Aryl hydrocarbon receptor-dependent up-regulation of the heterodimeric amino acid transporter LAT1 (SLC7A5)/CD98hc (SLC3A2) by diesel exhaust particle extract in human bronchial epithelial cells.
Journal: Toxicology and applied pharmacology 20160101
Title: DJ-1 mutation decreases astroglial release of inflammatory mediators.
Journal: Neurotoxicology 20160101
Title: Melanoma Expressed-CD70 Is Regulated by RhoA and MAPK Pathways without Affecting Vemurafenib Treatment Activity.
Journal: PloS one 20160101
Title: Taurocholate Induces Cyclooxygenase-2 Expression via the Sphingosine 1-phosphate Receptor 2 in a Human Cholangiocarcinoma Cell Line.
Journal: The Journal of biological chemistry 20151225
Title: Roles of oxidative stress and the ERK1/2, PTEN and p70S6K signaling pathways in arsenite-induced autophagy.
Journal: Toxicology letters 20151215
Title: Resveratrol Enhances Etoposide-Induced Cytotoxicity through Down-Regulating ERK1/2 and AKT-Mediated X-ray Repair Cross-Complement Group 1 (XRCC1) Protein Expression in Human Non-Small-Cell Lung Cancer Cells.
Journal: Basic & clinical pharmacology & toxicology 20151201
Title: Quercetin 3-O-glucoside suppresses epidermal growth factor-induced migration by inhibiting EGFR signaling in pancreatic cancer cells.
Journal: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20151201
Title: Atrazine-Mediated Disruption of Steroidogenesis in BLTK1 Murine Leydig Cells.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20151201
Title: Bisphenol A and Related Alkylphenols Exert Nongenomic Estrogenic Actions Through a G Protein-Coupled Estrogen Receptor 1 (Gper)/Epidermal Growth Factor Receptor (Egfr) Pathway to Inhibit Meiotic Maturation of Zebrafish Oocytes.
Journal: Biology of reproduction 20151201
Title: Bisphenol A-induced epithelial to mesenchymal transition is mediated by cyclooxygenase-2 up-regulation in human endometrial carcinoma cells.
Journal: Reproductive toxicology (Elmsford, N.Y.) 20151201
Title: Role of human pulmonary fibroblast-derived MCP-1 in cell activation and migration in experimental silicosis.
Journal: Toxicology and applied pharmacology 20151015
Title: EGFR Mutation Promotes Glioblastoma through Epigenome and Transcription Factor Network Remodeling.
Journal: Molecular cell 20151015
Title: The antioxidative potential of farrerol occurs via the activation of Nrf2 mediated HO-1 signaling in RAW 264.7 cells.
Journal: Chemico-biological interactions 20150905
Title: Modulation effects of sweroside isolated from the Lonicera japonica on melanin synthesis.
Journal: Chemico-biological interactions 20150805
Title: Insight into the molecular mechanism of heme oxygenase-1 induction by docosahexaenoic acid in U937 cells.
Journal: Chemico-biological interactions 20150805
Title: Ochratoxin A activates opposing c-MET/PI3K/Akt and MAPK/ERK 1-2 pathways in human proximal tubule HK-2 cells.
Journal: Archives of toxicology 20150801
Title: Tributyltin alters secretion of interleukin 1 beta from human immune cells.
Journal: Journal of applied toxicology : JAT 20150801
Title: Hyperphosphorylation of microfilament-associated proteins is involved in microcystin-LR-induced toxicity in HL7702 cells.
Journal: Environmental toxicology 20150708
Title: Down-regulation of aldo-keto reductase AKR1B10 gene expression by a phorbol ester via the ERK/c-Jun signaling pathway.
Journal: Chemico-biological interactions 20150605
Title: Increased hepatic Fatty Acid uptake and esterification contribute to tetracycline-induced steatosis in mice.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20150601
Title: Cyclosporin A upregulates ETB receptor in vascular smooth muscle via activation of mitogen-activating protein kinases and NF-κB pathways.
Journal: Toxicology letters 20150519
Title: TG-interacting factor transcriptionally induced by AKT/FOXO3A is a negative regulator that antagonizes arsenic trioxide-induced cancer cell apoptosis.
Journal: Toxicology and applied pharmacology 20150515
Title: Quercetin inhibits the migration and proliferation of astrocytes in wound healing.
Journal: Neuroreport 20150506
Title: Effects of exposure to benzo[a]pyrene on metastasis of breast cancer are mediated through ROS-ERK-MMP9 axis signaling.
Journal: Toxicology letters 20150505
Title: Combination of chrysin and cisplatin promotes the apoptosis of Hep G2 cells by up-regulating p53.
Journal: Chemico-biological interactions 20150505
Title: Trovafloxacin-induced replication stress sensitizes HepG2 cells to tumor necrosis factor-alpha-induced cytotoxicity mediated by extracellular signal-regulated kinase and ataxia telangiectasia and Rad3-related.
Journal: Toxicology 20150504
Title: S6 inhibition contributes to isoflurane neurotoxicity in the developing brain.
Journal: Toxicology letters 20150304
Title: Chrysin, baicalein and galangin are indirect activators of the human constitutive androstane receptor (CAR).
Journal: Toxicology letters 20150304
Title: MAPK pathway activation by chronic lead-exposure increases vascular reactivity through oxidative stress/cyclooxygenase-2-dependent pathways.
Journal: Toxicology and applied pharmacology 20150301
Title: Activation of MAPK pathways and downstream transcription factors in 2-aminobiphenyl-induced apoptosis.
Journal: Environmental toxicology 20150201
Title: Heat shock protein 27 phosphorylation in the proliferation and apoptosis of human umbilical vein endothelial cells induced by high glucose through the phosphoinositide 3‑kinase/Akt and extracellular signal‑regulated kinase 1/2 pathways.
Journal: Molecular medicine reports 20150201
Title: The role of mitogen-activated protein kinase in cadmium-induced primary rat cerebral cortical neurons apoptosis via a mitochondrial apoptotic pathway.
Journal: Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 20150101
Title: Elucidating mechanisms of toxicity using phenotypic data from primary human cell systems--a chemical biology approach for thrombosis-related side effects.
Journal: International journal of molecular sciences 20150101
Title: The E3 ubiquitin ligase Trim7 mediates c-Jun/AP-1 activation by Ras signalling.
Journal: Nature communications 20150101
Title: Antimetastatic Therapies of the Polysulfide Diallyl Trisulfide against Triple-Negative Breast Cancer (TNBC) via Suppressing MMP2/9 by Blocking NF-κB and ERK/MAPK Signaling Pathways.
Journal: PloS one 20150101
Title: Quercetin Attenuates Inflammatory Responses in BV-2 Microglial Cells: Role of MAPKs on the Nrf2 Pathway and Induction of Heme Oxygenase-1.
Journal: PloS one 20150101
Title: Effects of Camphorquinone on Cytotoxicity, Cell Cycle Regulation and Prostaglandin E2 Production of Dental Pulp Cells: Role of ROS, ATM/Chk2, MEK/ERK and Hemeoxygenase-1.
Journal: PloS one 20150101
Title: U0126, a mitogen-activated protein kinase kinase 1 and 2 (MEK1 and 2) inhibitor, selectively up-regulates main isoforms of CYP3A subfamily via a pregnane X receptor (PXR) in HepG2 cells.
Journal: Archives of toxicology 20141201
Title: Egr1 is rapidly and transiently induced by estrogen and bisphenol A via activation of nuclear estrogen receptor-dependent ERK1/2 pathway in the uterus.
Journal: Reproductive toxicology (Elmsford, N.Y.) 20141201
Title: The aryl hydrocarbon receptor suppresses osteoblast proliferation and differentiation through the activation of the ERK signaling pathway.
Journal: Toxicology and applied pharmacology 20141101
Title: Atrazine enhances progesterone production through activation of multiple signaling pathways in FSH-stimulated rat granulosa cells: evidence for premature luteinization.
Journal: Biology of reproduction 20141101
Title: Keratinocyte-derived IL-24 plays a role in the positive feedback regulation of epidermal inflammation in response to environmental and endogenous toxic stressors.
Journal: Toxicology and applied pharmacology 20141015
Title: Modulation of cytokine expression in human macrophages by endocrine-disrupting chemical Bisphenol-A.
Journal: Biochemical and biophysical research communications 20140905
Title: Role of SIRT1 in Streptococcus pneumoniae-induced human β-defensin-2 and interleukin-8 expression in A549 cell.
Journal: Molecular and cellular biochemistry 20140901
Title: Eupafolin inhibits PGE2 production and COX2 expression in LPS-stimulated human dermal fibroblasts by blocking JNK/AP-1 and Nox2/p47(phox) pathway.
Journal: Toxicology and applied pharmacology 20140901
Title: Glycogen synthase kinase 3 regulates cell death and survival signaling in tumor cells under redox stress.
Journal: Neoplasia (New York, N.Y.) 20140901
Title: Inhibition of cathepsin S induces autophagy and apoptosis in human glioblastoma cell lines through ROS-mediated PI3K/AKT/mTOR/p70S6K and JNK signaling pathways.
Journal: Toxicology letters 20140804
Title: Detection of key enzymes, free radical reaction products and activated signaling molecules as biomarkers of cell damage induced by benzo[a]pyrene in human keratinocytes.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20140801
Title: BNIP3 upregulation by ERK and JNK mediates cadmium-induced necrosis in neuronal cells.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20140801
Title: Reelin induces Erk1/2 signaling in cortical neurons through a non-canonical pathway.
Journal: The Journal of biological chemistry 20140718
Title: Loss of hnRNP K impairs synaptic plasticity in hippocampal neurons.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20140702
Title: Expression and regulation of stromal cell-derived factor-1 (SDF1) and chemokine CXC motif receptor 4 (CXCR4) in equine and bovine preovulatory follicles.
Journal: Molecular and cellular endocrinology 20140625
Title: Nonylphenol-induced apoptotic cell death in mouse TM4 Sertoli cells via the generation of reactive oxygen species and activation of the ERK signaling pathway.
Journal: Journal of applied toxicology : JAT 20140601
Title: Resveratrol protects primary cortical neuron cultures from transient oxygen-glucose deprivation by inhibiting MMP-9.
Journal: Molecular medicine reports 20140601
Title: Trovafloxacin potentiation of lipopolysaccharide-induced tumor necrosis factor release from RAW 264.7 cells requires extracellular signal-regulated kinase and c-Jun N-Terminal Kinase.
Journal: The Journal of pharmacology and experimental therapeutics 20140501
Title: Cadmium induces PC12 cells apoptosis via an extracellular signal-regulated kinase and c-Jun N-terminal kinase-mediated mitochondrial apoptotic pathway.
Journal: Biological trace element research 20140501
Title: Resveratrol down-regulates a glutamate-induced tissue plasminogen activator via Erk and AMPK/mTOR pathways in rat primary cortical neurons.
Journal: Food & function 20140501
Title: Resveratrol inhibits collagen I synthesis by suppressing IGF-1R activation in intestinal fibroblasts.
Journal: World journal of gastroenterology 20140428
Title: Pau d'arco activates Nrf2-dependent gene expression via the MEK/ERK-pathway.
Journal: The Journal of toxicological sciences 20140401
Title: Estrogen and pure antiestrogen fulvestrant (ICI 182 780) augment cell-matrigel adhesion of MCF-7 breast cancer cells through a novel G protein coupled estrogen receptor (GPR30)-to-calpain signaling axis.
Journal: Toxicology and applied pharmacology 20140301
Title: Acute exposure to lead acetate activates microglia and induces subsequent bystander neuronal death via caspase-3 activation.
Journal: Neurotoxicology 20140301
Title: ERK1/2 activation modulates pyocyanin-induced toxicity in A549 respiratory epithelial cells.
Journal: Chemico-biological interactions 20140205
Title: Hexabromocyclododecane facilitates FSH activation of ERK1/2 and AKT through epidermal growth factor receptor in rat granulosa cells.
Journal: Archives of toxicology 20140201
Title: Bisphenol A promotes dendritic morphogenesis of hippocampal neurons through estrogen receptor-mediated ERK1/2 signal pathway.
Journal: Chemosphere 20140201
Title: FGF16 promotes invasive behavior of SKOV-3 ovarian cancer cells through activation of mitogen-activated protein kinase (MAPK) signaling pathway.
Journal: The Journal of biological chemistry 20140117
Title: Humic acid in drinking well water induces inflammation through reactive oxygen species generation and activation of nuclear factor-κB/activator protein-1 signaling pathways: a possible role in atherosclerosis.
Journal: Toxicology and applied pharmacology 20140115
Title: Evaluation and mechanistic analysis of the cytotoxicity of the acyl glucuronide of nonsteroidal anti-inflammatory drugs.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20140101
Title: Celastrol prevents cadmium-induced neuronal cell death via targeting JNK and PTEN-Akt/mTOR network.
Journal: Journal of neurochemistry 20140101
Title: IL-6-mediated induction of matrix metalloproteinase-9 is modulated by JAK-dependent IL-10 expression in macrophages.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20140101
Title: Epidermal growth factor receptor signalling in human breast cancer cells operates parallel to estrogen receptor α signalling and results in tamoxifen insensitive proliferation.
Journal: BMC cancer 20140101
Title: Endocannabinoids modulate cortical development by configuring Slit2/Robo1 signalling.
Journal: Nature communications 20140101
Title: FSL-1 induces MMP-9 production through TLR-2 and NF-κB /AP-1 signaling pathways in monocytic THP-1 cells.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20140101
Title: Hyperosmolarity-induced up-regulation of claudin-4 mediated by NADPH oxidase-dependent H2O2 production and Sp1/c-Jun cooperation.
Journal: Biochimica et biophysica acta 20131201
Title: Nicotinic acetylcholine receptor antagonists alter the function and expression of serine racemase in PC-12 and 1321N1 cells.
Journal: Cellular signalling 20131201
Title: TRPM7 channel regulates PDGF-BB-induced proliferation of hepatic stellate cells via PI3K and ERK pathways.
Journal: Toxicology and applied pharmacology 20131101
Title: Chrysin enhances sensitivity of BEL-7402/ADM cells to doxorubicin by suppressing PI3K/Akt/Nrf2 and ERK/Nrf2 pathway.
Journal: Chemico-biological interactions 20131025
Title: Cadmium induces N-cadherin cleavage via ERK-mediated γ-secretase activation in C6 astroglia cells.
Journal: Toxicology letters 20131024
Title: NADPH oxidase/ROS-dependent PYK2 activation is involved in TNF-α-induced matrix metalloproteinase-9 expression in rat heart-derived H9c2 cells.
Journal: Toxicology and applied pharmacology 20131015
Title: Arsenic induces the expressions of angiogenesis-related factors through PI3K and MAPK pathways in SV-HUC-1 human uroepithelial cells.
Journal: Toxicology letters 20131009
Title: The ERK1/2 signaling pathway regulates 11beta-hydroxysteroid dehydrogenase type 2 expression in human trophoblast cells through a transcriptional mechanism.
Journal: Biology of reproduction 20131001
Title: Inhibitory effects of resveratrol on MCP-1, IL-6, and IL-8 production in human coronary artery smooth muscle cells.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20130901
Title: Phosphorylation of histone H3 at serine 10 has an essential role in arsenite-induced expression of FOS, EGR1 and IL8 mRNA in cultured human cell lines.
Journal: Journal of applied toxicology : JAT 20130801
Title: 4-Hydroxytamoxifen-stimulated processing of cyclin E is mediated via G protein-coupled receptor 30 (GPR30) and accompanied by enhanced migration in MCF-7 breast cancer cells.
Journal: Toxicology 20130705
Title: Expression of WWOX and FHIT is downregulated by exposure to arsenite in human uroepithelial cells.
Journal: Toxicology letters 20130704
Title: Apoptosis induced by trimethyltin chloride in human neuroblastoma cells SY5Y is regulated by a balance and cross-talk between NF-κB and MAPKs signaling pathways.
Journal: Archives of toxicology 20130701
Title: Involvement of ERK1/2 signaling pathway in atrazine action on FSH-stimulated LHR and CYP19A1 expression in rat granulosa cells.
Journal: Toxicology and applied pharmacology 20130701
Title: Repression of miR-143 mediates Cr (VI)-induced tumor angiogenesis via IGF-IR/IRS1/ERK/IL-8 pathway.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20130701
Title: Suppression of nuclear factor erythroid 2-related factor 2 via extracellular signal-regulated kinase contributes to bleomycin-induced oxidative stress and fibrogenesis.
Journal: Toxicology letters 20130620
Title: Arsenite suppression of BMP signaling in human keratinocytes.
Journal: Toxicology and applied pharmacology 20130615
Title: Tomatidine inhibits invasion of human lung adenocarcinoma cell A549 by reducing matrix metalloproteinases expression.
Journal: Chemico-biological interactions 20130525
Title: JNK and p38 MAPK regulate oxidative stress and the inflammatory response in chlorpyrifos-induced apoptosis.
Journal: Toxicology letters 20130426
Title: Mercury induces proliferation and reduces cell size in vascular smooth muscle cells through MAPK, oxidative stress and cyclooxygenase-2 pathways.
Journal: Toxicology and applied pharmacology 20130415
Title: Sodium arsenite induces cyclooxygenase-2 expression in human uroepithelial cells through MAPK pathway activation and reactive oxygen species induction.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20130401
Title: Cycloheximide stimulates suppressor of cytokine signaling-3 gene expression in 3T3-L1 adipocytes via the extracellular signal-regulated kinase pathway.
Journal: Toxicology letters 20130213
Title: p38 MAP kinase and ERK play an important role in nitric oxide-induced apoptosis of the mouse embryonic stem cells.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20130201
Title: Sodium arsenite exposure inhibits AKT and Stat3 activation, suppresses self-renewal and induces apoptotic death of embryonic stem cells.
Journal: Apoptosis : an international journal on programmed cell death 20130201
Title: Transient exposure to echinacoside is sufficient to activate Trk signaling and protect neuronal cells from rotenone.
Journal: Journal of neurochemistry 20130201
Title: Ethyl pyruvate protects rats from phosgene-induced pulmonary edema by inhibiting cyclooxygenase2 and inducible nitric oxide synthase expression.
Journal: Journal of applied toxicology : JAT 20130101
Title: The MAPK pathway signals telomerase modulation in response to isothiocyanate-induced DNA damage of human liver cancer cells.
Journal: PloS one 20130101
Title: A critical role for MAPK signalling pathways in the transcriptional regulation of toll like receptors.
Journal: PloS one 20130101
Title: Estrogen induction of telomerase activity through regulation of the mitogen-activated protein kinase (MAPK) dependent pathway in human endometrial cancer cells.
Journal: PloS one 20130101
Title: Inhibitory effects of resveratrol on PDGF-BB-induced retinal pigment epithelial cell migration via PDGFRβ, PI3K/Akt and MAPK pathways.
Journal: PloS one 20130101
Title: Oxidative stress and mitogen-activated protein kinase pathways involved in cadmium-induced BRL 3A cell apoptosis.
Journal: Oxidative medicine and cellular longevity 20130101
Title: Induction of miR-21-PDCD4 signaling by tungsten carbide-cobalt nanoparticles in JB6 cells involves ROS-mediated MAPK pathways.
Journal: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20130101
Title: MEK/ERK dependent activation of STAT1 mediates dasatinib-induced differentiation of acute myeloid leukemia.
Journal: PloS one 20130101
Title: Activation of Egr-1 in human lung epithelial cells exposed to silica through MAPKs signaling pathways.
Journal: PloS one 20130101
Title: Palmitic acid increases medial calcification by inducing oxidative stress.
Journal: Journal of vascular research 20130101
Title: Role of TRPM7 channels in hyperglycemia-mediated injury of vascular endothelial cells.
Journal: PloS one 20130101
Title: Gsta4 Null Mouse Embryonic Fibroblasts Exhibit Enhanced Sensitivity to Oxidants: Role of 4-Hydroxynonenal in Oxidant Toxicity.
Journal: Open journal of apoptosis 20130101
Title: High glucose-induced increased expression of endothelin-1 in human endothelial cells is mediated by activated CCAAT/enhancer-binding proteins.
Journal: PloS one 20130101
Title: 2-Deoxy-D-glucose cooperates with arsenic trioxide to induce apoptosis in leukemia cells: involvement of IGF-1R-regulated Akt/mTOR, MEK/ERK and LKB-1/AMPK signaling pathways.
Journal: Biochemical pharmacology 20121215
Title: Altered MAPK signaling in progressive deterioration of endothelial function in diabetic mice.
Journal: Diabetes 20121201
Title: Extracellular signal-regulated kinase 2 (ERK2) mediates phosphorylation and inactivation of nuclear interaction partner of anaplastic lymphoma kinase (NIPA) at G2/M.
Journal: The Journal of biological chemistry 20121102
Title: Eicosapentaenoic acid and docosahexaenoic acid inhibit macrophage-induced gastric cancer cell migration by attenuating the expression of matrix metalloproteinase 10.
Journal: The Journal of nutritional biochemistry 20121101
Title: Induction of ovarian maturation in Penaeus monodon by molecular signal interventional approach.
Journal: Journal of experimental zoology. Part B, Molecular and developmental evolution 20121101
Title: Pyk2 regulates H+-ATPase-mediated proton secretion in the outer medullary collecting duct via an ERK1/2 signaling pathway.
Journal: American journal of physiology. Renal physiology 20121101
Title: Hypoxic preconditioning up-regulates DJ-1 protein expression in rat heart-derived H9c2 cells through the activation of extracellular-regulated kinase 1/2 pathway.
Journal: Molecular and cellular biochemistry 20121101
Title: Hydrogen sulfide protects PC12 cells against reactive oxygen species and extracellular signal-regulated kinase 1/2-mediated downregulation of glutamate transporter-1 expression induced by chemical hypoxia.
Journal: International journal of molecular medicine 20121101
Title: Exploring the cyclooxygenase 2 (COX2)/15d-Δ(12,14)PGJ(2) system in hamster Sertoli cells: regulation by FSH/testosterone and relevance to glucose uptake.
Journal: General and comparative endocrinology 20121101
Title: Opposed arsenite-mediated regulation of p53-survivin is involved in neoplastic transformation, DNA damage, or apoptosis in human keratinocytes.
Journal: Toxicology 20121028
Title: Hyperphosphorylation of intermediate filament proteins is involved in microcystin-LR-induced toxicity in HL7702 cells.
Journal: Toxicology letters 20121017
Title: Phrenic long-term facilitation after acute intermittent hypoxia requires spinal ERK activation but not TrkB synthesis.
Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20121015
Title: Extinction of aversive memories associated with morphine withdrawal requires ERK-mediated epigenetic regulation of brain-derived neurotrophic factor transcription in the rat ventromedial prefrontal cortex.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20121003
Title: A novel epidermal growth factor-dependent extracellular signal-regulated MAP kinase cascade involved in sperm functionality in sheep.
Journal: Biology of reproduction 20121001
Title: Pro-apoptotic role of the MEK/ERK pathway in ursodeoxycholic acid-induced apoptosis in SNU601 gastric cancer cells.
Journal: Oncology reports 20121001
Title: Increased expression of CYP4Z1 promotes tumor angiogenesis and growth in human breast cancer.
Journal: Toxicology and applied pharmacology 20121001
Title: Mild stress of caffeine increased mtDNA content in skeletal muscle cells: the interplay between Ca2+ transients and nitric oxide.
Journal: Journal of muscle research and cell motility 20121001
Title: Inhibition of extracellular signal-regulated kinase activity improves cognitive function in Tg2576 mice.
Journal: Clinical and experimental pharmacology & physiology 20121001
Title: Spleen tyrosine kinase mediates high glucose-induced transforming growth factor-β1 up-regulation in proximal tubular epithelial cells.
Journal: Experimental cell research 20120910
Title: Role of Toll-like receptor 2 in the immune response against hepadnaviral infection.
Journal: Journal of hepatology 20120901
Title: Chronic exposure to laminar shear stress induces Kruppel-like factor 2 in glomerular endothelial cells and modulates interactions with co-cultured podocytes.
Journal: The international journal of biochemistry & cell biology 20120901
Title: Increased type 3 deiodinase expression in papillary thyroid carcinoma.
Journal: Thyroid : official journal of the American Thyroid Association 20120901
Title: A functional comparison between the HER2(high)/HER3 and the HER2(low)/HER3 dimers on heregulin-β1-induced MMP-1 and MMP-9 expression in breast cancer cells.
Journal: Experimental & molecular medicine 20120831
Title: Pimaric acid from Aralia cordata has an inhibitory effect on TNF-α-induced MMP-9 production and HASMC migration via down-regulated NF-κB and AP-1.
Journal: Chemico-biological interactions 20120830
Title: Extracellular ATP attenuates ischemia-induced caspase-3 cleavage in human endothelial cells.
Journal: Biochemical and biophysical research communications 20120824
Title: Regulation of fusion of the nucleolar precursor bodies following activation of mouse oocytes: roles of the maturation-promoting factors and mitogen-activated protein kinases.
Journal: Zygote (Cambridge, England) 20120801
Title: Effects of different activation regimens on pronuclear formation and developmental competence of in vitro-matured porcine oocytes after intracytoplasmic sperm injection.
Journal: Reproduction in domestic animals = Zuchthygiene 20120801
Title: Short-term fibronectin treatment induces endothelial-like and angiogenic properties in monocyte-derived immature dendritic cells: involvement of intracellular VEGF and MAPK regulation.
Journal: European journal of cell biology 20120801
Title: Targeting FAK radiosensitizes 3-dimensional grown human HNSCC cells through reduced Akt1 and MEK1/2 signaling.
Journal: International journal of radiation oncology, biology, physics 20120801
Title: Overexpression of Shp-2 attenuates apoptosis in neonatal rat cardiac myocytes through the ERK pathway.
Journal: Experimental and molecular pathology 20120801
Title: Antitumor activity of MEK and PI3K inhibitors against malignant pleural mesothelioma cells in vitro and in vivo.
Journal: International journal of oncology 20120801
Title: The Raf-1 inhibitor GW5074 and the ERK1/2 pathway inhibitor U0126 ameliorate PC12 cells apoptosis induced by 6-hydroxydopamine.
Journal: Die Pharmazie 20120801
Title: Peroxisome Proliferator-activated receptor γ activation by ligands and dephosphorylation induces proprotein convertase subtilisin kexin type 9 and low density lipoprotein receptor expression.
Journal: The Journal of biological chemistry 20120706
Title: TNFα-mediated apoptosis in human osteoarthritic chondrocytes sensitized by PI3K-NF-κB inhibitor, not mTOR inhibitor.
Journal: Rheumatology international 20120701
Title: Protective effects of ginsenosides against Bisphenol A-induced cytotoxicity in 15P-1 Sertoli cells via extracellular signal-regulated kinase 1/2 signalling and antioxidant mechanisms.
Journal: Basic & clinical pharmacology & toxicology 20120701
Title: Dasatinib synergizes with both cytotoxic and signal transduction inhibitors in heterogeneous breast cancer cell lines--lessons for design of combination targeted therapy.
Journal: Cancer letters 20120701
Title: Transforming growth factor β and Ras/MEK/ERK signaling regulate the expression level of a novel tumor suppressor Lefty.
Journal: Pancreas 20120701
Title: Cyclosporin A promotes crosstalk between human cytotrophoblast and decidual stromal cell through up-regulating CXCL12/CXCR4 interaction.
Journal: Human reproduction (Oxford, England) 20120701
Title: Monocyte chemoattractant protein-1 mediates angiotensin II-induced vascular smooth muscle cell proliferation via SAPK/JNK and ERK1/2.
Journal: Molecular and cellular biochemistry 20120701
Title: Allicin inhibits cell growth and induces apoptosis in U87MG human glioblastoma cells through an ERK-dependent pathway.
Journal: Oncology reports 20120701
Title: Pentoxifylline inhibits hepatic stellate cells proliferation via the Raf/ERK pathway.
Journal: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20120701
Title: MAP-kinase regulated cytosolic phospholipase A2 activity is essential for production of infectious hepatitis C virus particles.
Journal: PLoS pathogens 20120701
Title: Generation of induced pluripotent stem cells from primary chronic myelogenous leukemia patient samples.
Journal: Blood 20120628
Title: Regulatory mechanism of PAC1 gene expression via Sp1 by nerve growth factor in PC12 cells.
Journal: FEBS letters 20120612
Title: ERK1/2 signaling pathway in the release of VEGF from Müller cells in diabetes.
Journal: Investigative ophthalmology & visual science 20120608
Title: Effects of insulin and insulin-like growth factor 1 on osteoblast proliferation and differentiation: differential signalling via Akt and ERK.
Journal: Cell biochemistry and function 20120601
Title: Arsenic modulates heme oxygenase-1, interleukin-6, and vascular endothelial growth factor expression in endothelial cells: roles of ROS, NF-κB, and MAPK pathways.
Journal: Archives of toxicology 20120601
Title: CCK-induced reduction of food intake and hindbrain MAPK signaling are mediated by NMDA receptor activation.
Journal: Endocrinology 20120601
Title: Nicotinic neuromodulation in auditory cortex requires MAPK activation in thalamocortical and intracortical circuits.
Journal: Journal of neurophysiology 20120515
Title: ERK1/2 regulate exocytosis through direct phosphorylation of the exocyst component Exo70.
Journal: Developmental cell 20120515
Title: Nicotine up-regulates IL-8 expression in human gingival epithelial cells following stimulation with IL-1β or P. gingivalis lipopolysaccharide via nicotinic acetylcholine receptor signalling.
Journal: Archives of oral biology 20120501
Title: The adaptor protein NTAL enhances proximal signaling and potentiates corticosteroid-induced apoptosis in T-ALL.
Journal: Experimental hematology 20120501
Title: Nocodazole increases the ERK activity to enhance MKP-1expression which inhibits p38 activation induced by TNF-α.
Journal: Molecular and cellular biochemistry 20120501
Title: Crucial cross-talk of interleukin-1β and progesterone in human choriocarcinoma.
Journal: International journal of oncology 20120501
Title: TPA induces the expression of EC-SOD in human monocytic THP-1 cells: involvement of PKC, MEK/ERK and NOX-derived ROS.
Journal: Free radical research 20120501
Title: Pro-angiogenic effects of resveratrol in brain endothelial cells: nitric oxide-mediated regulation of vascular endothelial growth factor and metalloproteinases.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20120501
Title: Regulation of miRNA-21 by reactive oxygen species-activated ERK/NF-κB in arsenite-induced cell transformation.
Journal: Free radical biology & medicine 20120501
Title: Estrogen stimulates leptin receptor expression in ATDC5 cells via the estrogen receptor and extracellular signal-regulated kinase pathways.
Journal: The Journal of endocrinology 20120501
Title: Rhinovirus-induced MMP-9 expression is dependent on Fra-1, which is modulated by formoterol and dexamethasone.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20120501
Title: Cyclin D1 expression in podocytes: regulated by mitogens in collaboration with integrin-extracellular matrix interaction through extracellular signal-regulated kinase.
Journal: Experimental biology and medicine (Maywood, N.J.) 20120501
Title: Oncogenic KRAS-induced interleukin-8 overexpression promotes cell growth and migration and contributes to aggressive phenotypes of non-small cell lung cancer.
Journal: International journal of cancer 20120415
Title: Natriuretic effect of bufalin in isolated rat kidneys involves activation of the Na+-K+-ATPase-Src kinase pathway.
Journal: American journal of physiology. Renal physiology 20120415
Title: C-peptide induces human renal mesangial cell proliferation in vitro, activating Src-kinase, PI-3 kinase and ERK1/2.
Journal: Molecular and cellular endocrinology 20120404
Title: Enhanced phosphorylation of MAPKs by NE promotes TNF-α production by macrophage through α adrenergic receptor.
Journal: Inflammation 20120401
Title: IL-33 is induced by amyloid-β stimulation and regulates inflammatory cytokine production in retinal pigment epithelium cells.
Journal: Inflammation 20120401
Title: Heterogeneity in simvastatin-induced cytotoxicity in AML is caused by differences in Ras-isoprenylation.
Journal: Leukemia 20120401
Title: MEK/Erk-based negative feedback mechanism involved in control of Steel Factor-triggered production of Krüppel-like factor 2 in mast cells.
Journal: Cellular signalling 20120401
Title: Minimally modified LDL upregulates endothelin type B receptors in rat coronary artery via ERK1/2 MAPK and NF-κB pathways.
Journal: Biochimica et biophysica acta 20120401
Title: TOR signaling is involved in PTTH-stimulated ecdysteroidogenesis by prothoracic glands in the silkworm, Bombyx mori.
Journal: Insect biochemistry and molecular biology 20120401
Title: Mechanisms of the inhibition of nuclear factor-κB by morphine in neuronal cells.
Journal: Molecular pharmacology 20120401
Title: The progesterone-induced enhancement of object recognition memory consolidation involves activation of the extracellular signal-regulated kinase (ERK) and mammalian target of rapamycin (mTOR) pathways in the dorsal hippocampus.
Journal: Hormones and behavior 20120401
Title: Inhibition of sphingosine kinase 1 suppresses proliferation of glioma cells under hypoxia by attenuating activity of extracellular signal-regulated kinase.
Journal: Cell proliferation 20120401
Title: Intervention of human breast cell carcinogenesis chronically induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
Journal: Carcinogenesis 20120401
Title: Dehydroepiandrosterone indirectly inhibits human osteoclastic resorption via activating osteoblastic viability by the MAPK pathway.
Journal: Chinese medical journal 20120401
Title: 17beta-estradiol induces both up-regulation and processing of cyclin E in a calpain-dependent manner in MCF-7 breast cancer cells.
Journal: FEBS letters 20120323
Title: Cyclooxygenase-2 expression is up-regulated by 2-aminobiphenyl in a ROS and MAPK-dependent signaling pathway in a bladder cancer cell line.
Journal: Chemical research in toxicology 20120319
Title: Intra-amygdala inhibition of ERK(1/2) potentiates the discriminative stimulus effects of alcohol.
Journal: Behavioural brain research 20120317
Title: ERK/GSK3β/Snail signaling mediates radiation-induced alveolar epithelial-to-mesenchymal transition.
Journal: Free radical biology & medicine 20120315
Title: Reduction of metastasis, cell invasion, and adhesion in mouse osteosarcoma by YM529/ONO-5920-induced blockade of the Ras/MEK/ERK and Ras/PI3K/Akt pathway.
Journal: Toxicology and applied pharmacology 20120315
Title: Synergistic anti-tumor effects of RAD001 with MEK inhibitors in neuroendocrine tumors: a potential mechanism of therapeutic limitation of mTOR inhibitor.
Journal: Molecular and cellular endocrinology 20120305
Title: Inhibitory effect of bufalin and cinobufagin on steroidogenesis via the activation of ERK in human adrenocortical cells.
Journal: British journal of pharmacology 20120301
Title: Extracellular cysteine (Cys)/cystine (CySS) redox regulates metabotropic glutamate receptor 5 activity.
Journal: Biochimie 20120301
Title: NO donor and MEK inhibitor synergistically inhibit proliferation and invasion of cancer cells.
Journal: International journal of oncology 20120301
Title: Inhibition of ROS-activated ERK1/2 pathway contributes to the protection of H2S against chemical hypoxia-induced injury in H9c2 cells.
Journal: Molecular and cellular biochemistry 20120301
Title: CRP promotes MMP-10 expression via c-Raf/MEK/ERK and JAK1/ERK pathways in cardiomyocytes.
Journal: Cellular signalling 20120301
Title: Cyclosporine A--induced oxidative stress in human renal mesangial cells: a role for ERK 1/2 MAPK signaling.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120301
Title: Mechanism of exacerbative effect of progesterone on drug-induced liver injury.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120301
Title: In vivo natriuretic peptide reporter assay identifies chemical modifiers of hypertrophic cardiomyopathy signalling.
Journal: Cardiovascular research 20120301
Title: Cytoplasmic estrogen receptor β as a potential marker in human non-small cell lung carcinoma.
Journal: Expert opinion on therapeutic targets 20120301
Title: Involvement of IGF-I signaling pathway in the regulation of steroidogenesis in mouse Leydig cells treated with fenvalerate.
Journal: Toxicology 20120226
Title: MAPK- and PKC/CREB-dependent induction of interleukin-11 by the environmental contaminant formaldehyde in human bronchial epithelial cells.
Journal: Toxicology 20120206
Title: Involvement of K(ATP)/PI (3)K/AKT/Bcl-2 pathway in hydrogen sulfide-induced neuroprotection against the toxicity of 1-methy-4-phenylpyridinium ion.
Journal: Journal of molecular neuroscience : MN 20120201
Title: Reduction by strontium of the bone marrow adiposity in mice and repression of the adipogenic commitment of multipotent C3H10T1/2 cells.
Journal: Bone 20120201
Title: JS-K, a glutathione S-transferase-activated nitric oxide donor with antineoplastic activity in malignant gliomas.
Journal: Neurosurgery 20120201
Title: p53 rescue through HDM2 antagonism suppresses melanoma growth and potentiates MEK inhibition.
Journal: The Journal of investigative dermatology 20120201
Title: TPA-induced p21 expression augments G2/M arrest through a p53-independent mechanism in human breast cancer cells.
Journal: Oncology reports 20120201
Title: The role of MAPK and Nrf2 pathways in ketanserin-elicited attenuation of cigarette smoke-induced IL-8 production in human bronchial epithelial cells.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120201
Title: Toll-like receptor 4 and MYD88-dependent signaling mechanisms of the innate immune system are essential for the response to lipopolysaccharide by epithelial and stromal cells of the bovine endometrium.
Journal: Biology of reproduction 20120201
Title: Deltamethrin, a type II pyrethroid insecticide, has neurotrophic effects on neurons with continuous activation of the Bdnf promoter.
Journal: Neuropharmacology 20120201
Title: An NF-κB-independent and Erk1/2-dependent mechanism controls CXCL8/IL-8 responses of airway epithelial cells to cadmium.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120201
Title: The novel dual PI3K/mTOR inhibitor GDC-0941 synergizes with the MEK inhibitor U0126 in non-small cell lung cancer cells.
Journal: Molecular medicine reports 20120201
Title: Involvement of the extracellular signal-regulated kinase 1/2 signaling pathway in amylin's eating inhibitory effect.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20120201
Title: Smad7 acts as a negative regulator of the epidermal growth factor (EGF) signaling pathway in breast cancer cells.
Journal: Cancer letters 20120128
Title: Inhibition of signal transducer and activator of transcription 3 (STAT3) attenuates interleukin-6 (IL-6)-induced collagen synthesis and resultant hypertrophy in rat heart.
Journal: The Journal of biological chemistry 20120120
Title: Endogenous ouabain regulates cell viability.
Journal: American journal of physiology. Cell physiology 20120115
Title: Prostaglandin E2 enhances interleukin-8 production via EP4 receptor in human pulmonary microvascular endothelial cells.
Journal: American journal of physiology. Lung cellular and molecular physiology 20120115
Title: Curcumin regulates airway epithelial cell cytokine responses to the pollutant cadmium.
Journal: Biochemical and biophysical research communications 20120106
Title: 5-Azacytidine induces cardiac differentiation of human umbilical cord-derived mesenchymal stem cells by activating extracellular regulated kinase.
Journal: Stem cells and development 20120101
Title: EGF receptor inhibitors increase ErbB3 mRNA and protein levels in breast cancer cells.
Journal: Cellular signalling 20120101
Title: Human foetal intestinal fibroblasts are hyper-responsive to lipopolysaccharide stimulation.
Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20120101
Title: Cadmium increases HIF-1 and VEGF expression through ROS, ERK, and AKT signaling pathways and induces malignant transformation of human bronchial epithelial cells.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120101
Title: gp130 cytokines stimulate proteasomal degradation of tyrosine hydroxylase via extracellular signal regulated kinases 1 and 2.
Journal: Journal of neurochemistry 20120101
Title: Hypoxia promotes rabbit pulmonary artery smooth muscle cells proliferation through a 15-LOX-2 product 15(S)-hydroxyeicosatetraenoic acid.
Journal: Prostaglandins, leukotrienes, and essential fatty acids 20120101
Title: DJ-1 upregulates tyrosine hydroxylase gene expression by activating its transcriptional factor Nurr1 via the ERK1/2 pathway.
Journal: The international journal of biochemistry & cell biology 20120101
Title: Mutual regulation of growth hormone and bone morphogenetic protein system in steroidogenesis by rat granulosa cells.
Journal: Endocrinology 20120101
Title: Two closely related human members of chitinase-like family, CHI3L1 and CHI3L2, activate ERK1/2 in 293 and U373 cells but have the different influence on cell proliferation.
Journal: International journal of biological sciences 20120101
Title: Sensitization of dural afferents underlies migraine-related behavior following meningeal application of interleukin-6 (IL-6).
Journal: Molecular pain 20120101
Title: Aristolochic acid I induced autophagy extenuates cell apoptosis via ERK 1/2 pathway in renal tubular epithelial cells.
Journal: PloS one 20120101
Title: Antimetastatic effects of norcantharidin on hepatocellular carcinoma by transcriptional inhibition of MMP-9 through modulation of NF-kB activity.
Journal: PloS one 20120101
Title: Anti-inflammatory role of the cAMP effectors Epac and PKA: implications in chronic obstructive pulmonary disease.
Journal: PloS one 20120101
Title: Effects of dihydropyridine calcium channel blockers on oxidized low-density lipoprotein induced proliferation and oxidative stress of vascular smooth muscle cells.
Journal: BMC research notes 20120101
Title: MUC1 contributes to BPDE-induced human bronchial epithelial cell transformation through facilitating EGFR activation.
Journal: PloS one 20120101
Title: Cockroach allergen Per a 7 down-regulates expression of Toll-like receptor 9 and IL-12 release from P815 cells through PI3K and MAPK signaling pathways.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101
Title: Inhibitory effect of liquiritigenin on migration via downregulation proMMP-2 and PI3K/Akt signaling pathway in human lung adenocarcinoma A549 cells.
Journal: Nutrition and cancer 20120101
Title: Ethanol-mediated regulation of cytochrome P450 2A6 expression in monocytes: role of oxidative stress-mediated PKC/MEK/Nrf2 pathway.
Journal: PloS one 20120101
Title: Mifepristone increases the cytotoxicity of uterine natural killer cells by acting as a glucocorticoid antagonist via ERK activation.
Journal: PloS one 20120101
Title: Multi-walled carbon nanotubes induce COX-2 and iNOS expression via MAP kinase-dependent and -independent mechanisms in mouse RAW264.7 macrophages.
Journal: Particle and fibre toxicology 20120101
Title: Radiation-induced c-Jun activation depends on MEK1-ERK1/2 signaling pathway in microglial cells.
Journal: PloS one 20120101
Title: Camel milk triggers apoptotic signaling pathways in human hepatoma HepG2 and breast cancer MCF7 cell lines through transcriptional mechanism.
Journal: Journal of biomedicine & biotechnology 20120101
Title: Regulation of interleukin-1alpha and tumor necrosis factor-alpha-induced interleukin-8 production by amnion-derived (WISH) cells.
Journal: Clinical and experimental obstetrics & gynecology 20120101
Title: GEP100/Arf6 is required for epidermal growth factor-induced ERK/Rac1 signaling and cell migration in human hepatoma HepG2 cells.
Journal: PloS one 20120101
Title: MAPK and JAK-STAT signaling pathways are involved in the oxidative stress-induced decrease in expression of surfactant protein genes.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101
Title: Interleukin-1 induction of aggrecanase gene expression in human articular chondrocytes is mediated by mitogen-activated protein kinases.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101
Title: An in vivo C. elegans model system for screening EGFR-inhibiting anti-cancer drugs.
Journal: PloS one 20120101
Title: Perlecan Domain V induces VEGf secretion in brain endothelial cells through integrin α5β1 and ERK-dependent signaling pathways.
Journal: PloS one 20120101
Title: Antagonizing retinoic acid and FGF/MAPK pathways control posterior body patterning in the invertebrate chordate Ciona intestinalis.
Journal: PloS one 20120101
Title: LH and hCG action on the same receptor results in quantitatively and qualitatively different intracellular signalling.
Journal: PloS one 20120101
Title: Effects of intravitreal insulin and insulin signaling cascade inhibitors on emmetropization in the chick.
Journal: Molecular vision 20120101
Title: Angiotensin II protects primary rat hepatocytes against bile salt-induced apoptosis.
Journal: PloS one 20120101
Title: Crosstalk between Raf/MEK/ERK and PI3K/AKT in suppression of Bax conformational change by Grp75 under glucose deprivation conditions.
Journal: Journal of molecular biology 20111216
Title: Interplay between vascular endothelial growth factor (VEGF) and nuclear factor erythroid 2-related factor-2 (Nrf2): implications for preeclampsia.
Journal: The Journal of biological chemistry 20111216
Title: Advanced-glycation-end-product-cholesterol-aggregated-protein accelerates the proliferation of mesangial cells mediated by transforming-growth-factor-beta 1 receptors and the ERK-MAPK pathway.
Journal: European journal of pharmacology 20111215
Title: Flavonoids inhibit high glucose-induced up-regulation of ICAM-1 via the p38 MAPK pathway in human vein endothelial cells.
Journal: Biochemical and biophysical research communications 20111202
Title: Molecular changes during arsenic-induced cell transformation.
Journal: Journal of cellular physiology 20111201
Title: Neuroprotective effects of MAPK/ERK1/2 and calpain inhibitors on lactacystin-induced cell damage in primary cortical neurons.
Journal: Neurotoxicology 20111201
Title: Extracellular progranulin protects cortical neurons from toxic insults by activating survival signaling.
Journal: Neurobiology of aging 20111201
Title: Is galectin-1 a trigger for trophoblast cell fusion?: the MAP-kinase pathway and syncytium formation in trophoblast tumour cells BeWo.
Journal: Molecular human reproduction 20111201
Title: TGF-β1 mediates sirolimus and cyclosporine A-induced alteration of barrier function in renal epithelial cells via a noncanonical ERK1/2 signaling pathway.
Journal: American journal of physiology. Renal physiology 20111201
Title: CaMKII is involved in cadmium activation of MAPK and mTOR pathways leading to neuronal cell death.
Journal: Journal of neurochemistry 20111201
Title: MAPK and AP-1 proteins are increased in term pre-labour fetal membranes overlying the cervix: regulation of enzymes involved in the degradation of fetal membranes.
Journal: Placenta 20111201
Title: Phosphorylation of JAK2 by serotonin 5-HT (2A) receptor activates both STAT3 and ERK1/2 pathways and increases growth of JEG-3 human placental choriocarcinoma cell.
Journal: Placenta 20111201
Title: Fibroblast growth factor regulates human neuroectoderm specification through ERK1/2-PARP-1 pathway.
Journal: Stem cells (Dayton, Ohio) 20111201
Title: Signalling and chemosensitivity assays in melanoma: is mutated status a prerequisite for targeted therapy?
Journal: Experimental dermatology 20111201
Title: A metabolic perturbation by U0126 identifies a role for glutamine in resveratrol-induced cell death.
Journal: Cancer biology & therapy 20111201
Title: [Effects of valsartan and U0126 on atrial fibrosis and connexin40 remodeling in rats].
Journal: Zhonghua xin xue guan bing za zhi 20111201
Title: [The pharmacological mechanism of gastrodin on calcitonin gene-related peptide of cultured rat trigeminal ganglion].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20111201
Title: Osterix is regulated by Erk1/2 during osteoblast differentiation.
Journal: Biochemical and biophysical research communications 20111125
Title: Growth factors stimulate expression of neuronal and glial miR-132.
Journal: Neuroscience letters 20111121
Title: Ellipticine induces apoptosis in human endometrial cancer cells: the potential involvement of reactive oxygen species and mitogen-activated protein kinases.
Journal: Toxicology 20111118
Title: An extracellular signal-regulated kinase 2 survival pathway mediates resistance of human mesothelioma cells to asbestos-induced injury.
Journal: American journal of respiratory cell and molecular biology 20111101
Title: ARF triggers cell G1 arrest by a P53 independent ERK pathway.
Journal: Molecular and cellular biochemistry 20111101
Title: The activation of NMDA receptor-ERK pathway in the central amygdala is required for the expression of morphine-conditioned place preference in the rat.
Journal: Neurotoxicity research 20111101
Title: Endothelial-cardiomyocyte crosstalk enhances pharmacological cardioprotection.
Journal: Journal of molecular and cellular cardiology 20111101
Title: Resveratrol inhibits the epidermal growth factor-induced epithelial mesenchymal transition in MCF-7 cells.
Journal: Cancer letters 20111101
Title: Lysophosphatidic acid 5 receptor induces activation of Na(+)/H(+) exchanger 3 via apical epidermal growth factor receptor in intestinal epithelial cells.
Journal: American journal of physiology. Cell physiology 20111101
Title: Antiviral activity of the MEK-inhibitor U0126 against pandemic H1N1v and highly pathogenic avian influenza virus in vitro and in vivo.
Journal: Antiviral research 20111101
Title: Apo- and holo-lactoferrin are both internalized by lactoferrin receptor via clathrin-mediated endocytosis but differentially affect ERK-signaling and cell proliferation in Caco-2 cells.
Journal: Journal of cellular physiology 20111101
Title: Dorsomorphin stimulates neurite outgrowth in PC12 cells via activation of a protein kinase A-dependent MEK-ERK1/2 signaling pathway.
Journal: Genes to cells : devoted to molecular & cellular mechanisms 20111101
Title: Mechanisms underlying gemcitabine resistance in pancreatic cancer and sensitisation by the iMiD™ lenalidomide.
Journal: Anticancer research 20111101
Title: Large-scale discovery of ERK2 substrates identifies ERK-mediated transcriptional regulation by ETV3.
Journal: Science signaling 20111025
Title: Active ERK1/2 protein interacts with the phosphorylated nuclear constitutive active/androstane receptor (CAR; NR1I3), repressing dephosphorylation and sequestering CAR in the cytoplasm.
Journal: The Journal of biological chemistry 20111014
Title: Differential adenosine uptake in mixed neuronal/glial or purified glial cultures of avian retinal cells: modulation by adenosine metabolism and the ERK cascade.
Journal: Biochemical and biophysical research communications 20111014
Title: Human gastrin mRNA expression up-regulated by Helicobacter pylori CagA through MEK/ERK and JAK2-signaling pathways in gastric cancer cells.
Journal: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20111001
Title: Phenethyl isothiocyanate sensitizes human cervical cancer cells to apoptosis induced by cisplatin.
Journal: Molecular nutrition & food research 20111001
Title: Cisplatin treatment of primary and metastatic epithelial ovarian carcinomas generates residual cells with mesenchymal stem cell-like profile.
Journal: Journal of cellular biochemistry 20111001
Title: ERK1/2 and ERK5 have distinct roles in the regulation of brain-derived neurotrophic factor expression.
Journal: Journal of neuroscience research 20111001
Title: Arsenic-induced alteration in intracellular calcium homeostasis induces head kidney macrophage apoptosis involving the activation of calpain-2 and ERK in Clarias batrachus.
Journal: Toxicology and applied pharmacology 20111001
Title: Human corneal endothelial cells employ phosphorylation of p27(Kip1) at both Ser10 and Thr187 sites for FGF-2-mediated cell proliferation via PI 3-kinase.
Journal: Investigative ophthalmology & visual science 20111001
Title: Elucidating the mechanism of regulation of transforming growth factor β Type II receptor expression in human lung cancer cell lines.
Journal: Neoplasia (New York, N.Y.) 20111001
Title: Fully activated MEK1 exhibits compromised affinity for binding of allosteric inhibitors U0126 and PD0325901.
Journal: Biochemistry 20110920
Title: Protein kinase D1 mediates synergistic MMP-3 expression induced by TNF-α and bradykinin in human colonic myofibroblasts.
Journal: Biochemical and biophysical research communications 20110916
Title: Curcumin enhances the mitomycin C-induced cytotoxicity via downregulation of MKK1/2-ERK1/2-mediated Rad51 expression in non-small cell lung cancer cells.
Journal: Toxicology and applied pharmacology 20110915
Title: Cisplatin transiently up-regulates hHR23 expression through enhanced translational efficiency in A549 adenocarcinoma cells.
Journal: Toxicology letters 20110910
Title: Cysteinyl leukotrienes synthesis is involved in aristolochic acid I-induced apoptosis in renal proximal tubular epithelial cells.
Journal: Toxicology 20110905
Title: Involvement of protein kinase Cdelta/extracellular signal-regulated kinase/poly(ADP-ribose) polymerase-1 (PARP-1) signaling pathway in histamine-induced up-regulation of histamine H1 receptor gene expression in HeLa cells.
Journal: The Journal of biological chemistry 20110902
Title: ERK phosphorylation predicts synergism between gemcitabine and the epidermal growth factor receptor inhibitor AG1478.
Journal: Lung cancer (Amsterdam, Netherlands) 20110901
Title: Doxycycline up-regulates the expression of IL-6 and GM-CSF via MAPK/ERK and NF-κB pathways in mouse thymic epithelial cells.
Journal: International immunopharmacology 20110901
Title: Angiotensin II type 1 receptor signalling regulates microRNA differentially in cardiac fibroblasts and myocytes.
Journal: British journal of pharmacology 20110901
Title: Estrogen-related receptor α regulates skeletal myocyte differentiation via modulation of the ERK MAP kinase pathway.
Journal: American journal of physiology. Cell physiology 20110901
Title: Arsenic trioxide induces autophagy and apoptosis in human glioma cells in vitro and in vivo through downregulation of survivin.
Journal: Journal of molecular medicine (Berlin, Germany) 20110901
Title: Suppression of TG-interacting factor sensitizes arsenic trioxide-induced apoptosis in human hepatocellular carcinoma cells.
Journal: The Biochemical journal 20110901
Title: tPA contributes to impaired NMDA cerebrovasodilation after traumatic brain injury through activation of JNK MAPK.
Journal: Neurological research 20110901
Title: Bisphenol-A rapidly enhanced passive avoidance memory and phosphorylation of NMDA receptor subunits in hippocampus of young rats.
Journal: Toxicology and applied pharmacology 20110901
Title: Arsenic increases lipopolysaccharide-dependent expression of interleukin-8 gene by stimulating a redox-sensitive pathway that strengthens p38-kinase activation.
Journal: Molecular immunology 20110901
Title: [Selective ERβ action of dehydroepiandrosterone for osteoblast cell line].
Journal: Zhonghua fu chan ke za zhi 20110901
Title: Dynamic mass redistribution as a means to measure and differentiate signaling via opioid and cannabinoid receptors.
Journal: Assay and drug development technologies 20110801
Title: MAPKs ERK and p38, but not JNK phosphorylation, modulate IL-6 and TNF-α secretion following OK-432 in vitro stimulation of purified human monocytes.
Journal: Scandinavian journal of immunology 20110801
Title: Prevention of bronchial hyperplasia by EGFR pathway inhibitors in an organotypic culture model.
Journal: Cancer prevention research (Philadelphia, Pa.) 20110801
Title: Small molecule inhibitors of the host cell COX/AREG/EGFR/ERK pathway attenuate cytomegalovirus-induced pathogenesis.
Journal: Experimental and molecular pathology 20110801
Title: A novel 3-dimensional culture system uncovers growth stimulatory actions by TGFβ in pancreatic cancer cells.
Journal: Cancer biology & therapy 20110801
Title: 5-Methoxyflavanone induces cell cycle arrest at the G2/M phase, apoptosis and autophagy in HCT116 human colon cancer cells.
Journal: Toxicology and applied pharmacology 20110801
Title: Differential effects of growth factors on oligodendrocyte progenitor migration.
Journal: European journal of cell biology 20110801
Title: The ETS family transcription factor ELK-1 regulates induction of the cell cycle-regulatory gene p21(Waf1/Cip1) and the BAX gene in sodium arsenite-exposed human keratinocyte HaCaT cells.
Journal: The Journal of biological chemistry 20110729
Title: T-cell receptor signaling enhances transcriptional elongation from latent HIV proviruses by activating P-TEFb through an ERK-dependent pathway.
Journal: Journal of molecular biology 20110729
Title: Signaling cascades mediate astrocyte death induced by zinc.
Journal: Toxicology letters 20110728
Title: Up-regulation of extracellular signal-regulated kinase 1/2-dependent thymidylate synthase and thymidine phosphorylase contributes to cisplatin resistance in human non-small-cell lung cancer cells.
Journal: The Journal of pharmacology and experimental therapeutics 20110701
Title: Endocytosis of resveratrol via lipid rafts and activation of downstream signaling pathways in cancer cells.
Journal: Cancer prevention research (Philadelphia, Pa.) 20110701
Title: Potential upstream regulators and downstream targets of AMP-activated kinase signaling during oocyte maturation in a marine worm.
Journal: Reproduction (Cambridge, England) 20110701
Title: ERK is involved in EGF-mediated protection of tight junctions, but not adherens junctions, in acetaldehyde-treated Caco-2 cell monolayers.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20110701
Title: Growth hormone-stimulated insulin-like growth factor-1 expression in rainbow trout (Oncorhynchus mykiss) hepatocytes is mediated by ERK, PI3K-AKT, and JAK-STAT.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20110701
Title: MEK inhibition suppresses the development of lung fibrosis in the bleomycin model.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20110701
Title: Monocyte chemotactic protein-3 induces human coronary smooth muscle cell proliferation.
Journal: Atherosclerosis 20110701
Title: Forced expression of cyclin-dependent kinase 6 confers resistance of pro-B acute lymphocytic leukemia to Gleevec treatment.
Journal: Molecular and cellular biology 20110701
Title: Involvement of 4E-BP phosphorylation in embryonic development of the silkworm, Bombyx mori.
Journal: Journal of insect physiology 20110701
Title: Silencing of BNIP3 results from promoter methylation by DNA methyltransferase 1 induced by the mitogen-activated protein kinase pathway.
Journal: Molecules and cells 20110630
Title: Bim protein degradation contributes to cisplatin resistance.
Journal: The Journal of biological chemistry 20110624
Title: Diphenyl diselenide induces apoptotic cell death and modulates ERK1/2 phosphorylation in human neuroblastoma SH-SY5Y cells.
Journal: Archives of toxicology 20110601
Title: Steroidogenesis and the influence of MAPK activity during in vitro maturation of porcine cumulus oocyte complexes.
Journal: Reproduction in domestic animals = Zuchthygiene 20110601
Title: Decrease in transient receptor potential melastatin 6 mRNA stability caused by rapamycin in renal tubular epithelial cells.
Journal: Biochimica et biophysica acta 20110601
Title: Mild stretch activates cPLA2 in alveolar type II epithelial cells independently through the MEK/ERK and PI3K pathways.
Journal: Biochimica et biophysica acta 20110601
Title: PDGF-induced vascular smooth muscle cell proliferation is associated with dysregulation of insulin receptor substrates.
Journal: American journal of physiology. Cell physiology 20110601
Title: Involvement of P2X(7) purinergic receptor and MEK1/2 in interleukin-8 up-regulation by LL-37 in human gingival fibroblasts.
Journal: Journal of periodontal research 20110601
Title: Acrylamide up-regulates cyclooxygenase-2 expression through the MEK/ERK signaling pathway in mouse epidermal cells.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110601
Title: Ubiquitination regulates the assembly of VLDL in HepG2 cells and is the committing step of the apoB-100 ERAD pathway.
Journal: Journal of lipid research 20110601
Title: GPCR/EGFR cross talk is conserved in gonadal and adrenal steroidogenesis but is uniquely regulated by matrix metalloproteinases 2 and 9 in the ovary.
Journal: Molecular endocrinology (Baltimore, Md.) 20110601
Title: ERK-associated changes of AP-1 proteins during fear extinction.
Journal: Molecular and cellular neurosciences 20110601
Title: Tissue factor pathway inhibitor 2 is induced by thrombin in human macrophages.
Journal: Biochimica et biophysica acta 20110601
Title: Cortical neurons develop insulin resistance and blunted Akt signaling: a potential mechanism contributing to enhanced ischemic injury in diabetes.
Journal: Antioxidants & redox signaling 20110515
Title: Cellular antioxidant adaptive survival response to 6-hydroxydopamine-induced nitrosative cell death in C6 glioma cells.
Journal: Toxicology 20110510
Title: Proteomic analysis of human transplanted submandibular gland in patients with epiphora after transplantation.
Journal: Journal of proteome research 20110506
Title: The fungicide ciclopirox inhibits lymphatic endothelial cell tube formation by suppressing VEGFR-3-mediated ERK signaling pathway.
Journal: Oncogene 20110505
Title: Comparison of intracellular signalling by insulin and the hypermitogenic AspB10 analogue in MCF-7 breast adenocarcinoma cells.
Journal: Journal of applied toxicology : JAT 20110501
Title: Involvement of glycogen synthase kinase-3β in arsenic trioxide-induced p21 expression.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20110501
Title: Nobiletin attenuates VLDL overproduction, dyslipidemia, and atherosclerosis in mice with diet-induced insulin resistance.
Journal: Diabetes 20110501
Title: Reactive oxygen species hydrogen peroxide mediates Kaposi's sarcoma-associated herpesvirus reactivation from latency.
Journal: PLoS pathogens 20110501
Title: The inhibition of MAPK potentiates the anti-angiogenic efficacy of mTOR inhibitors.
Journal: Biochemical and biophysical research communications 20110422
Title: ERK/MAPK pathways play critical roles in EGFR ligands-induced MMP1 expression.
Journal: Biochemical and biophysical research communications 20110422
Title: Improvement in neurological outcome and abolition of cerebrovascular endothelin B and 5-hydroxytryptamine 1B receptor upregulation through mitogen-activated protein kinase kinase 1/2 inhibition after subarachnoid hemorrhage in rats.
Journal: Journal of neurosurgery 20110401
Title: Fluid shear stress induces renal epithelial gene expression through polycystin-2-dependent trafficking of extracellular regulated kinase.
Journal: Nephron. Physiology 20110401
Title: The combi-targeting concept: mechanism of action of the pleiotropic combi-molecule RB24 and discovery of a novel cell signaling-based combination principle.
Journal: Cellular signalling 20110401
Title: β2-adrenergic receptors inhibit the expression of collagen type II in growth plate chondrocytes by stimulating the AP-1 factor Jun-B.
Journal: American journal of physiology. Endocrinology and metabolism 20110401
Title: Lactone form 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) stimulate the osteoblastic differentiation of mouse periodontal ligament cells via the ERK pathway.
Journal: Journal of periodontal research 20110401
Title: Schisandrin B elicits a glutathione antioxidant response and protects against apoptosis via the redox-sensitive ERK/Nrf2 pathway in AML12 hepatocytes.
Journal: Free radical research 20110401
Title: Peroxiredoxin 6 phosphorylation and subsequent phospholipase A2 activity are required for agonist-mediated activation of NADPH oxidase in mouse pulmonary microvascular endothelium and alveolar macrophages.
Journal: The Journal of biological chemistry 20110401
Title: The gsp oncogene disrupts Ras/ERK-dependent prolactin gene regulation in gsp inducible somatotroph cell line.
Journal: Endocrinology 20110401
Title: Molecular regulation of NADPH oxidase 5 via the MAPK pathway.
Journal: American journal of physiology. Heart and circulatory physiology 20110401
Title: Dual-specific phosphatase-6 (Dusp6) and ERK mediate AMPA receptor-induced oligodendrocyte death.
Journal: The Journal of biological chemistry 20110401
Title: The basolateral amygdala regulates adaptation to stress via β-adrenergic receptor-mediated reductions in phosphorylated extracellular signal-regulated kinase.
Journal: Neuroscience 20110331
Title: Cadmium induces phosphorylation and stabilization of c-Fos in HK-2 renal proximal tubular cells.
Journal: Toxicology and applied pharmacology 20110315
Title: Hexavalent chromium-induced apoptosis of granulosa cells involves selective sub-cellular translocation of Bcl-2 members, ERK1/2 and p53.
Journal: Toxicology and applied pharmacology 20110315
Title: Involvement of heme oxygenase-1 induction via Nrf2/ARE activation in protection against H2O2-induced PC12 cell death by a metabolite of sesamin contained in sesame seeds.
Journal: Bioorganic & medicinal chemistry 20110315
Title: Lipopolysaccharide inhibits transforming growth factor-beta1-stimulated Smad6 expression by inducing phosphorylation of the linker region of Smad3 through a TLR4-IRAK1-ERK1/2 pathway.
Journal: FEBS letters 20110309
Title: Docetaxel inhibits cyclooxygenase-2 induction in vascular smooth muscle cells.
Journal: European journal of pharmacology 20110305
Title: Intracellular signals mediating the food intake-suppressive effects of hindbrain glucagon-like peptide-1 receptor activation.
Journal: Cell metabolism 20110302
Title: Stimulation of pro-inflammatory responses by mebendazole in human monocytic THP-1 cells through an ERK signaling pathway.
Journal: Archives of toxicology 20110301
Title: Prolonged mechanical stretch is associated with upregulation of hypoxia-inducible factors and reduced contraction in rat inferior vena cava.
Journal: Journal of vascular surgery 20110301
Title: Cellular and biomolecular responses of human ovarian cancer cells to cytostatic dinuclear platinum(II) complexes.
Journal: Apoptosis : an international journal on programmed cell death 20110301
Title: Activation of CaMKII and ERK1/2 contributes to the time-dependent potentiation of Ca2+ response elicited by repeated application of capsaicin in rat DRG neurons.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20110301
Title: The mitogenic effect of testosterone and 17β-estradiol on airway smooth muscle cells.
Journal: Steroids 20110301
Title: Transforming growth factor β1 down-regulates Runx-2 and alkaline phosphatase activity of human dental pulp cells via ALK5/Smad2/3 signaling.
Journal: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20110301
Title: Effects of DNMT and MEK inhibitors on the expression of RECK, MMP-9, -2, uPA and VEGF in response to arsenite stimulation in human uroepithelial cells.
Journal: Toxicology letters 20110225
Title: [GRP75 overexpression inhibits apoptosis induced by glucose deprivation via Raf/Mek/Erk1/2 signaling pathway].
Journal: Sheng li xue bao : [Acta physiologica Sinica] 20110225
Title: MEK-independent survival of B-RAFV600E melanoma cells selected for resistance to apoptosis induced by the RAF inhibitor PLX4720.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110215
Title: Mitogen-activated protein kinases ERK 1/2- and p38-GATA4 pathways mediate the Ang II-induced activation of FGF2 gene in neonatal rat cardiomyocytes.
Journal: Biochemical pharmacology 20110215
Title: Neuronal differentiation of C17.2 neural stem cells induced by a natural flavonoid, baicalin.
Journal: Chembiochem : a European journal of chemical biology 20110211
Title: Structure-activity relationships between the Aconitum C20-diterpenoid alkaloid derivatives and the growth suppressive activities of Non-Hodgkin's lymphoma Raji cells and human hematopoietic stem/progenitor cells.
Journal: Investigational new drugs 20110201
Title: CB2 cannabinoid receptor targets mitogenic Gi protein-cyclin D1 axis in osteoblasts.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20110201
Title: Luteinizing hormone receptor mRNA down-regulation is mediated through ERK-dependent induction of RNA binding protein.
Journal: Molecular endocrinology (Baltimore, Md.) 20110201
Title: Thrombin-induced chemokine production in endometrial stromal cells.
Journal: Human reproduction (Oxford, England) 20110201
Title: Activation of the Raf-MEK-ERK pathway is required for neutrophil extracellular trap formation.
Journal: Nature chemical biology 20110201
Title: Integrin {alpha}3, but not {beta}1, regulates islet cell survival and function via PI3K/Akt signaling pathways.
Journal: Endocrinology 20110201
Title: Reactive oxygen species are indispensable in ovulation.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20110125
Title: Effects of MEK and DNMT inhibitors on arsenic-treated human uroepithelial cells in relation to Cyclin-D1 and p16.
Journal: Toxicology letters 20110115
Title: α-TEA cooperates with MEK or mTOR inhibitors to induce apoptosis via targeting IRS/PI3K pathways.
Journal: British journal of cancer 20110104
Title: Serotonin activates MAP kinase and PI3K/Akt signaling pathways in prostate cancer cell lines.
Journal: Urologic oncology 20110101
Title: Oxidative stress-induced attenuation of thrombospondin-1 expression in primary rat astrocytes.
Journal: Journal of cellular biochemistry 20110101
Title: Characterized polysaccharides from black soybean induce granulocyte colony-stimulated factor gene expression in a phosphoinositide 3-kinase-dependent manner.
Journal: Immunological investigations 20110101
Title: ERK1 and ERK2 kinases activate hydroxyurea-induced S-phase checkpoint in MCF7 cells by mediating ATR activation.
Journal: Cellular signalling 20110101
Title: A trifluoromethyl analog of verbenachalcone promotes neurite outgrowth and cell proliferation of NeuroScreen-1 cells.
Journal: Cellular and molecular neurobiology 20110101
Title: C-reactive protein impairs hepatic insulin sensitivity and insulin signaling in rats: role of mitogen-activated protein kinases.
Journal: Hepatology (Baltimore, Md.) 20110101
Title: Selective ERK activation differentiates mouse and human tolerogenic dendritic cells, expands antigen-specific regulatory T cells, and suppresses experimental inflammatory arthritis.
Journal: Arthritis and rheumatism 20110101
Title: Deciphering the signaling pathways of cancer stem cells of glioblastoma multiforme: role of Akt/mTOR and MAPK pathways.
Journal: Advances in enzyme regulation 20110101
Title: LH-induced neuregulin 1 (NRG1) type III transcripts control granulosa cell differentiation and oocyte maturation.
Journal: Molecular endocrinology (Baltimore, Md.) 20110101
Title: Mycoplasma hyopneumoniae induces pro-inflammatory cytokine and nitric oxide production through NFκB and MAPK pathways in RAW264.7 cells.
Journal: Veterinary research communications 20110101
Title: Down-regulation of CYLD as a trigger for NF-κB activation and a mechanism of apoptotic resistance in hepatocellular carcinoma cells.
Journal: International journal of oncology 20110101
Title: Distinctive mechanism for sustained TGF-β signaling and growth inhibition: MEK1 activation-dependent stabilization of type II TGF-β receptors.
Journal: Molecular cancer research : MCR 20110101
Title: Lactobacillus casei prevents impaired barrier function in intestinal epithelial cells.
Journal: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20110101
Title: Duration and magnitude of extracellular signal-regulated protein kinase phosphorylation determine adipogenesis or osteogenesis in human bone marrow-derived stem cells.
Journal: Yonsei medical journal 20110101
Title: Serotonin triggers a transient epigenetic mechanism that reinstates adult visual cortex plasticity in rats.
Journal: The European journal of neuroscience 20110101
Title: Coupling of α1-adrenoceptors to ERK1/2 in the human prostate.
Journal: Urologia internationalis 20110101
Title: Biphasic activation of PI3K/Akt and MAPK/Erk1/2 signaling pathways in bovine herpesvirus type 1 infection of MDBK cells.
Journal: Veterinary research 20110101
Title: The effect of ATM and ERK1/2 inhibition on mitoxantrone-induced cell death of leukaemic cells.
Journal: Folia biologica 20110101
Title: Cancer-induced bone pain sequentially activates the ERK/MAPK pathway in different cell types in the rat spinal cord.
Journal: Molecular pain 20110101
Title: Resveratrol inhibits Cdk5 activity through regulation of p35 expression.
Journal: Molecular pain 20110101
Title: The β-carboline alkaloid harmol induces cell death via autophagy but not apoptosis in human non-small cell lung cancer A549 cells.
Journal: Biological & pharmaceutical bulletin 20110101
Title: Unfertilized Xenopus eggs die by Bad-dependent apoptosis under the control of Cdk1 and JNK.
Journal: PloS one 20110101
Title: Aberrant activation of ERK/FOXM1 signaling cascade triggers the cell migration/invasion in ovarian cancer cells.
Journal: PloS one 20110101
Title: PI3K and ERK-induced Rac1 activation mediates hypoxia-induced HIF-1α expression in MCF-7 breast cancer cells.
Journal: PloS one 20110101
Title: Hydrogen sulfide protects against chemical hypoxia-induced injury by inhibiting ROS-activated ERK1/2 and p38MAPK signaling pathways in PC12 cells.
Journal: PloS one 20110101
Title: Mechanisms for vascular cell adhesion molecule-1 activation of ERK1/2 during leukocyte transendothelial migration.
Journal: PloS one 20110101
Title: Blocking the PI3K/AKT and MEK/ERK signaling pathways can overcome gefitinib-resistance in non-small cell lung cancer cell lines.
Journal: Advances in medical sciences 20110101
Title: Carbon monoxide induced PPARγ SUMOylation and UCP2 block inflammatory gene expression in macrophages.
Journal: PloS one 20110101
Title: Erk1/2 mediates leptin receptor signaling in the ventral tegmental area.
Journal: PloS one 20110101
Title: Activation of vasculogenic progenitor cells by ent-16α,17-dihydroxy-kauran-19-oic acid.
Journal: Biological & pharmaceutical bulletin 20110101
Title: Decrease in the production of β-amyloid by berberine inhibition of the expression of β-secretase in HEK293 cells.
Journal: BMC neuroscience 20110101
Title: Ursodeoxycholic acid is conjugated with taurine to promote secretin-stimulated biliary hydrocholeresis in the normal rat.
Journal: PloS one 20110101
Title: The mammalian MAPK/ERK pathway exhibits properties of a negative feedback amplifier.
Journal: Science signaling 20101221
Title: CCK1 and CCK2 receptors are expressed on pancreatic stellate cells and induce collagen production.
Journal: The Journal of biological chemistry 20101210
Title: An ERK-dependent pathway to Noxa expression regulates apoptosis by platinum-based chemotherapeutic drugs.
Journal: Oncogene 20101209
Title: p22phox-dependent NADPH oxidase activity is required for megakaryocytic differentiation.
Journal: Cell death and differentiation 20101201
Title: Thioredoxin protects fetal type II epithelial cells from hyperoxia-induced injury.
Journal: Pediatric pulmonology 20101201
Title: Non-dioxin-like PCBs interact with benzo[a]pyrene-induced p53-responses and inhibit apoptosis.
Journal: Toxicology and applied pharmacology 20101201
Title: Mnk mediates integrin α6β4-dependent eIF4E phosphorylation and translation of VEGF mRNA.
Journal: Molecular cancer research : MCR 20101201
Title: Duplicate preconditioning with sevoflurane in vitro improves neuroprotection in rat brain via activating the extracellular signal-regulated protein kinase.
Journal: Neuroscience bulletin 20101201
Title: [Cross-talk between PI3K/Akt and MEK/ERK pathways regulates human hepatocellular carcinoma cell cycle progression under endoplasmic reticulum stress].
Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20101201
Title: A formulated red ginseng extract rescues PC12 cells from PCB-induced oxidative cell death through Nrf2-mediated upregulation of heme oxygenase-1 and glutamate cysteine ligase.
Journal: Toxicology 20101128
Title: Cisplatin induces apoptosis through the ERK-p66shc pathway in renal proximal tubule cells.
Journal: Cancer letters 20101128
Title: Upregulation of contractile endothelin type B receptors by lipid-soluble cigarette smoking particles in rat cerebral arteries via activation of MAPK.
Journal: Toxicology and applied pharmacology 20101115
Title: Antagonistic roles of the ERK and p38 MAPK signalling pathways in globin expression, haem biosynthesis and iron uptake.
Journal: The Biochemical journal 20101115
Title: Dynamic simulations of pathways downstream of ERBB-family, including mutations and treatments: concordance with experimental results.
Journal: Current cancer drug targets 20101101
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters 20101101
Title: Crosstalk between the PI3K/mTOR and MEK/ERK pathways involved in the maintenance of self-renewal and tumorigenicity of glioblastoma stem-like cells.
Journal: Stem cells (Dayton, Ohio) 20101101
Title: Cadmium ions promote monocytic differentiation of human leukemia HL-60 cells treated with 1α,25-dihydroxyvitamin D3.
Journal: Biological chemistry 20101101
Title: DNA damage-induced modulation of GLUT3 expression is mediated through p53-independent extracellular signal-regulated kinase signaling in HeLa cells.
Journal: Molecular cancer research : MCR 20101101
Title: Effects of human full-length amelogenin on the proliferation of human mesenchymal stem cells derived from bone marrow.
Journal: Cell and tissue research 20101101
Title: Terbinafine stimulates the pro-inflammatory responses in human monocytic THP-1 cells through an ERK signaling pathway.
Journal: Life sciences 20101023
Title: 3-Caffeoyl, 4-dihydrocaffeoylquinic acid from Salicornia herbacea inhibits tumor cell invasion by regulating protein kinase C-delta-dependent matrix metalloproteinase-9 expression.
Journal: Toxicology letters 20101005
Title: Cadmium ions induce monocytic production of tumor necrosis factor-alpha by inhibiting mitogen activated protein kinase dephosphorylation.
Journal: Toxicology letters 20101005
Title: ERK1/2 signaling pathways involved in VEGF release in diabetic rat retina.
Journal: Investigative ophthalmology & visual science 20101001
Title: Resveratrol regulates p66Shc activation in HaCaT cells.
Journal: Experimental dermatology 20101001
Title: Leukocyte common antigen-related (LAR) tyrosine phosphatase positively regulates osteoblast differentiation by modulating extracellular signal-regulated kinase (ERK) activation.
Journal: Molecules and cells 20101001
Title: Targeting of the orphan receptor GPR35 by pamoic acid: a potent activator of extracellular signal-regulated kinase and β-arrestin2 with antinociceptive activity.
Journal: Molecular pharmacology 20101001
Title: Quercetin potentiates insulin secretion and protects INS-1 pancreatic β-cells against oxidative damage via the ERK1/2 pathway.
Journal: British journal of pharmacology 20101001
Title: [Simvastatin suppress lipopolysaccharides induced upregulation of lipoprotein associated phospholipase A(2) expression in macrophages via inactivation of p38MAPK pathway].
Journal: Zhonghua xin xue guan bing za zhi 20101001
Title: Rosmarinus officinalis polyphenols activate cholinergic activities in PC12 cells through phosphorylation of ERK1/2.
Journal: Journal of ethnopharmacology 20100915
Title: Suppression mechanisms of flavonoids on aryl hydrocarbon receptor-mediated signal transduction.
Journal: Archives of biochemistry and biophysics 20100901
Title: Bone marrow-derived mesenchymal stem cells attenuate amyloid β-induced memory impairment and apoptosis by inhibiting neuronal cell death.
Journal: Current Alzheimer research 20100901
Title: Multiple protein kinase pathways mediate amplified IL-6 release by human lung fibroblasts co-exposed to nickel and TLR-2 agonist, MALP-2.
Journal: Toxicology and applied pharmacology 20100901
Title: Dexamethasone enhances the norepinephrine-induced ERK/MAPK intracellular pathway possibly via dysregulation of the alpha2-adrenergic receptor: implications for antidepressant drug mechanism of action.
Journal: European journal of cell biology 20100901
Title: The role of neural stem cells for in vitro models of schizophrenia: neuroprotection via Akt/ERK signal regulation.
Journal: Schizophrenia research 20100901
Title: Aquaporin-4 in manganese-treated cultured astrocytes.
Journal: Glia 20100901
Title: Ovarian steroids, mitogen-activated protein kinases, and/or aspartic proteinases cooperate to control endometrial remodeling by regulating gene expression in the stroma and glands.
Journal: Endocrinology 20100901
Title: Cocarcinogenic effect of capsaicin involves activation of EGFR signaling but not TRPV1.
Journal: Cancer research 20100901
Title: PTEN sensitizes MDA-MB-468 cells to inhibition of MEK/Erk signaling for the blockade of cell proliferation.
Journal: Oncology reports 20100901
Title: Inhibition of ERK1/2 prevents neural and mesendodermal differentiation and promotes human embryonic stem cell self-renewal.
Journal: Stem cell research 20100901
Title: Fibroblast growth factor type 2 signaling is critical for DNA repair in human keratinocyte stem cells.
Journal: Stem cells (Dayton, Ohio) 20100901
Title: MAP kinase-signaling controls nuclear translocation of tripeptidyl-peptidase II in response to DNA damage and oxidative stress.
Journal: Biochemical and biophysical research communications 20100827
Title: Zinc released from injured cells is acting via the Zn2+-sensing receptor, ZnR, to trigger signaling leading to epithelial repair.
Journal: The Journal of biological chemistry 20100820
Title: MEK inhibitors suppress beta-amyloid production by altering the level of a beta-C-terminal fragment of amyloid precursor protein in neuronal cells.
Journal: FEBS letters 20100804
Title: Emodin enhances cisplatin-induced cytotoxicity via down-regulation of ERCC1 and inactivation of ERK1/2.
Journal: Lung cancer (Amsterdam, Netherlands) 20100801
Title: Fibroblast growth factor 8 induced downregulation of thrombospondin 1 is mediated by the MEK/ERK and PI3K pathways in breast cancer cells.
Journal: Growth factors (Chur, Switzerland) 20100801
Title: Up-regulation of heme oxygenase-1 expression through CaMKII-ERK1/2-Nrf2 signaling mediates the anti-inflammatory effect of bisdemethoxycurcumin in LPS-stimulated macrophages.
Journal: Free radical biology & medicine 20100801
Title: The mechanism of ascorbic acid-induced differentiation of ATDC5 chondrogenic cells.
Journal: American journal of physiology. Endocrinology and metabolism 20100801
Title: Magnetic stimulation influences injury-induced migration of white matter astrocytes.
Journal: Electromagnetic biology and medicine 20100801
Title: Reactive oxygen species, Ki-Ras, and mitochondrial superoxide dismutase cooperate in nerve growth factor-induced differentiation of PC12 cells.
Journal: The Journal of biological chemistry 20100730
Title: Cytokine-associated drug toxicity in human hepatocytes is associated with signaling network dysregulation.
Journal: Molecular bioSystems 20100715
Title: Cadmium-induced hormetic effect in differentiated Caco-2 cells: ERK and p38 activation without cell proliferation stimulation.
Journal: Journal of cellular physiology 20100701
Title: Sorafenib combined vitamin K induces apoptosis in human pancreatic cancer cell lines through RAF/MEK/ERK and c-Jun NH2-terminal kinase pathways.
Journal: Journal of cellular physiology 20100701
Title: Inhibition of extracellular signal-regulated kinases 1/2 provides neuroprotection in spinal cord ischemia/reperfusion injury in rats: relationship with the nuclear factor-kappaB-regulated anti-apoptotic mechanisms.
Journal: Journal of neurochemistry 20100701
Title: ERK signaling leads to mitochondrial dysfunction in extracellular zinc-induced neurotoxicity.
Journal: Journal of neurochemistry 20100701
Title: Regulation of (pro)renin receptor expression by glucose-induced mitogen-activated protein kinase, nuclear factor-kappaB, and activator protein-1 signaling pathways.
Journal: Endocrinology 20100701
Title: Deciphering mechanisms controlling placental artery endothelial cell migration stimulated by vascular endothelial growth factor.
Journal: Endocrinology 20100701
Title: Interleukin-7 promotes the survival of human CD4+ effector/memory T cells by up-regulating Bcl-2 proteins and activating the JAK/STAT signalling pathway.
Journal: Immunology 20100701
Title: Selective BRAFV600E inhibition enhances T-cell recognition of melanoma without affecting lymphocyte function.
Journal: Cancer research 20100701
Title: Sorafenib, a multikinase inhibitor, enhances the response of melanoma to regional chemotherapy.
Journal: Molecular cancer therapeutics 20100701
Title: Chitinase induce the release of IL-8 in human airway epithelial cells, via Ca2+-dependent PKC and ERK pathways.
Journal: Scandinavian journal of immunology 20100701
Title: Calcitonin gene-related peptide induces proliferation and monocyte chemoattractant protein-1 expression via extracellular signal-regulated kinase activation in rat osteoblasts.
Journal: Chinese medical journal 20100701
Title: [Helicobacter pylori cytotoxin associated protein CagA regulates gastrin gene promoter activity].
Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20100701
Title: Activation of 5-lipoxygenase is required for nicotine mediated epithelial-mesenchymal transition and tumor cell growth.
Journal: Cancer letters 20100628
Title: Activation of metabotropic glutamate receptor 5 in the amygdala modulates pain-like behavior.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100616
Title: Suppression of PMA-induced tumor cell invasion by dihydroartemisinin via inhibition of PKCalpha/Raf/MAPKs and NF-kappaB/AP-1-dependent mechanisms.
Journal: Biochemical pharmacology 20100615
Title: Protective effect of all-trans retinoic acid on NMDA-induced neuronal cell death in rat retina.
Journal: European journal of pharmacology 20100610
Title: Molecular mechanisms involving sigma receptor-mediated induction of MCP-1: implication for increased monocyte transmigration.
Journal: Blood 20100610
Title: cAMP-induced auditory supporting cell proliferation is mediated by ERK MAPK signaling pathway.
Journal: Journal of the Association for Research in Otolaryngology : JARO 20100601
Title: Membrane-impermeable estrogen is involved in regulation of calbindin-D9k expression via non-genomic pathways in a rat pituitary cell line, GH3 cells.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20100601
Title: Involvement of the MEKK1 signaling pathway in the regulation of epicardial cell behavior by hyaluronan.
Journal: Cellular signalling 20100601
Title: Distinct effects of knocking down MEK1 and MEK2 on replication of herpes simplex virus type 2.
Journal: Virus research 20100601
Title: 2,3,7,8-tetrachlorodibenzo-p-dioxin impairs an insulin signaling pathway through the induction of tumor necrosis factor-alpha in adipocytes.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20100601
Title: Quantitative assessment of neurite outgrowth in human embryonic stem cell-derived hN2 cells using automated high-content image analysis.
Journal: Neurotoxicology 20100601
Title: PAR1 and PAR2 couple to overlapping and distinct sets of G proteins and linked signaling pathways to differentially regulate cell physiology.
Journal: Molecular pharmacology 20100601
Title: Role of ERK map kinase and CRM1 in IL-1beta-stimulated release of HMGB1 from cortical astrocytes.
Journal: Glia 20100601
Title: Extracellular signal-regulated kinase and GEF-H1 mediate depolarization-induced Rho activation and paracellular permeability increase.
Journal: American journal of physiology. Cell physiology 20100601
Title: A novel bile acid-activated vitamin D receptor signaling in human hepatocytes.
Journal: Molecular endocrinology (Baltimore, Md.) 20100601
Title: Enhancing the GLP-1 receptor signaling pathway leads to proliferation and neuroprotection in human neuroblastoma cells.
Journal: Journal of neurochemistry 20100601
Title: Deferoxamine mesylate is toxic for retinal pigment epithelium cells in vitro, and its toxicity is mediated by p38.
Journal: Cutaneous and ocular toxicology 20100601
Title: Astrocytic activation and an inhibition of MAP kinases are required for proteinase-activated receptor-2-mediated protection from neurotoxicity.
Journal: Journal of neurochemistry 20100601
Title: Increased expression of glucose transporter 3 in gerbil brains following magnesium sulfate treatment and focal cerebral ischemic injury.
Journal: Cell biochemistry and function 20100601
Title: Neuroprotective potential of CB1 receptor agonists in an in vitro model of Huntington's disease.
Journal: British journal of pharmacology 20100601
Title: Inhibition of MAP kinase promotes the recruitment of corepressor SMRT by tamoxifen-bound estrogen receptor alpha and potentiates tamoxifen action in MCF-7 cells.
Journal: Biochemical and biophysical research communications 20100528
Title: Modulation of metalloproteinase-9 in U87MG glioblastoma cells by A3 adenosine receptors.
Journal: Biochemical pharmacology 20100515
Title: Rapid effects of phytoestrogens on human colonic smooth muscle are mediated by oestrogen receptor beta.
Journal: Molecular and cellular endocrinology 20100514
Title: Role for the proapoptotic factor BIM in mediating imatinib-induced apoptosis in a c-KIT-dependent gastrointestinal stromal tumor cell line.
Journal: The Journal of biological chemistry 20100507
Title: Delayed activation of extracellular-signal-regulated kinase 1/2 is involved in genistein- and equol-induced cell proliferation and estrogen-receptor-alpha-mediated transcription in MCF-7 breast cancer cells.
Journal: The Journal of nutritional biochemistry 20100501
Title: NR2D-containing NMDA receptors mediate tissue plasminogen activator-promoted neuronal excitotoxicity.
Journal: Cell death and differentiation 20100501
Title: The DSCs-expressed CD82 controls the invasiveness of trophoblast cells via integrinbeta1/MAPK/MAPK3/1 signaling pathway in human first-trimester pregnancy.
Journal: Biology of reproduction 20100501
Title: Long-term nicotine exposure-induced chemoresistance is mediated by activation of Stat3 and downregulation of ERK1/2 via nAChR and beta-adrenoceptors in human bladder cancer cells.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20100501
Title: Prolonged activation of ERK triggers glutamate-induced apoptosis of astrocytes: neuroprotective effect of FK506.
Journal: Journal of neurochemistry 20100501
Title: Resolvins RvE1 and RvD1 attenuate inflammatory pain via central and peripheral actions.
Journal: Nature medicine 20100501
Title: Differential functions of growth factor receptor-bound protein 7 (GRB7) and its variant GRB7v in ovarian carcinogenesis.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20100501
Title: EphrinBs/EphBs signaling is involved in modulation of spinal nociceptive processing through a mitogen-activated protein kinases-dependent mechanism.
Journal: Anesthesiology 20100501
Title: Impaired SHP2-mediated extracellular signal-regulated kinase activation contributes to gefitinib sensitivity of lung cancer cells with epidermal growth factor receptor-activating mutations.
Journal: Cancer research 20100501
Title: Stimulatory effects of areca nut extracts on prostaglandin E2 production by human polymorphonuclear leukocytes.
Journal: Journal of periodontology 20100501
Title: Enhancing therapeutic efficacy by targeting non-oncogene addicted cells with combinations of signal transduction inhibitors and chemotherapy.
Journal: Cell cycle (Georgetown, Tex.) 20100501
Title: Extra-cellular signal-regulated kinase 1/2 (ERK1/2) activated in the hippocampal CA1 neurons is critical for retrieval of auditory trace fear memory.
Journal: Brain research 20100422
Title: Tetramethylpyrazine promotes proliferation and differentiation of neural stem cells from rat brain in hypoxic condition via mitogen-activated protein kinases pathway in vitro.
Journal: Neuroscience letters 20100419
Title: 2,3,7,8-Tetrachlorodibenzo-para-dioxin increases aromatase (CYP19) mRNA stability in MCF-7 cells.
Journal: Molecular and cellular endocrinology 20100412
Title: Phosphorylation of the MAPK pathway has an essential role in the acrosome reaction in miniature pig sperm.
Journal: Reproduction in domestic animals = Zuchthygiene 20100401
Title: Loss of 15-hydroxyprostaglandin dehydrogenase increases prostaglandin E2 in pancreatic tumors.
Journal: Pancreas 20100401
Title: Defective TPA signalling compromises HaCat cells as a human in vitro skin carcinogenesis model.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20100401
Title: NF-kappaB activation stimulates osteogenic differentiation of mesenchymal stem cells derived from human adipose tissue by increasing TAZ expression.
Journal: Journal of cellular physiology 20100401
Title: EGF and its related growth factors mediate sodium transport in mpkCCDc14 cells via ErbB2 (neu/HER-2) receptor.
Journal: Journal of cellular physiology 20100401
Title: alphaB-crystallin is mutant B-RAF regulated and contributes to cyclin D1 turnover in melanocytic cells.
Journal: Pigment cell & melanoma research 20100401
Title: The Wilms' tumor suppressor WT1 induces estrogen-independent growth and anti-estrogen insensitivity in ER-positive breast cancer MCF7 cells.
Journal: Oncology reports 20100401
Title: Sustained activation of ERK signaling in astrocytes is critical for neuronal injury-induced monocyte chemoattractant protein-1 production in rat corticostriatal slice cultures.
Journal: The European journal of neuroscience 20100401
Title: Effects of progesterone on the growth regulation in classical progesterone receptor-negative malignant melanoma cells.
Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20100401
Title: [IL-27 regulates the expression of Mac-1, fMLP-R and IL-1beta in human neutrophils through p38 MAPK and PI3K signal pathways].
Journal: Zhongguo shi yan xue ye xue za zhi 20100401
Title: A receptor-independent, cell-based JAK activation assay for screening for JAK3-specific inhibitors.
Journal: Journal of immunological methods 20100331
Title: Purification of a peptide from seahorse, that inhibits TPA-induced MMP, iNOS and COX-2 expression through MAPK and NF-kappaB activation, and induces human osteoblastic and chondrocytic differentiation.
Journal: Chemico-biological interactions 20100330
Title: Cellular factors involved in CXCL8 expression induced by glycated serum albumin in vascular smooth muscle cells.
Journal: Atherosclerosis 20100301
Title: Hepatitis C virus RNA replication is regulated by Ras-Erk signalling.
Journal: The Journal of general virology 20100301
Title: Transcriptional regulation of the small GTPase RhoB gene by TGF{beta}-induced signaling pathways.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20100301
Title: De novo synthesis of {beta}-catenin via H-Ras and MEK regulates airway smooth muscle growth.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20100301
Title: Extracellular Mg(2+) regulates the tight junctional localization of claudin-16 mediated by ERK-dependent phosphorylation.
Journal: Biochimica et biophysica acta 20100301
Title: Three-dimensional overlay culture models of human breast cancer reveal a critical sensitivity to mitogen-activated protein kinase kinase inhibitors.
Journal: The Journal of pharmacology and experimental therapeutics 20100301
Title: Edaravone improves the expression of nerve growth factor in human astrocytes subjected to hypoxia/reoxygenation.
Journal: Neuroscience research 20100301
Title: Sirolimus and cyclosporine A alter barrier function in renal proximal tubular cells through stimulation of ERK1/2 signaling and claudin-1 expression.
Journal: American journal of physiology. Renal physiology 20100301
Title: Akt-1 mediates survival of chondrocytes from endoplasmic reticulum-induced stress.
Journal: Journal of cellular physiology 20100301
Title: Resveratrol reduces glutamate-mediated monocyte chemotactic protein-1 expression via inhibition of extracellular signal-regulated kinase 1/2 pathway in rat hippocampal slice cultures.
Journal: Journal of neurochemistry 20100301
Title: Exocyst Sec10 protects epithelial barrier integrity and enhances recovery following oxidative stress, by activation of the MAPK pathway.
Journal: American journal of physiology. Renal physiology 20100301
Title: Ras-induced resistance to lapatinib is overcome by MEK inhibition.
Journal: Current cancer drug targets 20100301
Title: Toll-like receptor ligands cause proinflammatory and prodiabetic activation of adipocytes via phosphorylation of extracellular signal-regulated kinase and c-Jun N-terminal kinase but not interferon regulatory factor-3.
Journal: Endocrinology 20100301
Title: Effects of AG490 on lens epithelial cell death induced by H(2)O(2).
Journal: Japanese journal of ophthalmology 20100301
Title: Glucocorticoid attenuates brain-derived neurotrophic factor-dependent upregulation of glutamate receptors via the suppression of microRNA-132 expression.
Journal: Neuroscience 20100217
Title: Upregulation of early growth response factor-1 by bile acids requires mitogen-activated protein kinase signaling.
Journal: Toxicology and applied pharmacology 20100215
Title: Fcgamma receptor cross-linking stimulates cell proliferation of macrophages via the ERK pathway.
Journal: The Journal of biological chemistry 20100205
Title: FGF2-activated ERK mitogen-activated protein kinase enhances Runx2 acetylation and stabilization.
Journal: The Journal of biological chemistry 20100205
Title: Lycopene suppresses LPS-induced NO and IL-6 production by inhibiting the activation of ERK, p38MAPK, and NF-kappaB in macrophages.
Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20100201
Title: Induction of dual specificity phosphatase 1 (DUSP1) by gonadotropin-releasing hormone (GnRH) and the role for gonadotropin subunit gene expression in mouse pituitary gonadotroph L beta T2 cells.
Journal: Biology of reproduction 20100201
Title: Oxidants induce alternative splicing of alpha-synuclein: Implications for Parkinson's disease.
Journal: Free radical biology & medicine 20100201
Title: The EGF receptor-sox2-EGF receptor feedback loop positively regulates the self-renewal of neural precursor cells.
Journal: Stem cells (Dayton, Ohio) 20100201
Title: Assessment of the role of MAP kinase in mediating activity-dependent transcriptional activation of the immediate early gene Arc/Arg3.1 in the dentate gyrus in vivo.
Journal: Learning & memory (Cold Spring Harbor, N.Y.) 20100201
Title: Induction of tissue inhibitor of matrix metalloproteinase-2 by cholesterol depletion leads to the conversion of proMMP-2 into active MMP-2 in human dermal fibroblasts.
Journal: Experimental & molecular medicine 20100131
Title: PACAP stimulation of maturational gonadotropin secretion in goldfish involves extracellular signal-regulated kinase, but not nitric oxide or guanylate cyclase, signaling.
Journal: General and comparative endocrinology 20100101
Title: The PI3K/Akt and mTOR/P70S6K signaling pathways in human uveal melanoma cells: interaction with B-Raf/ERK.
Journal: Investigative ophthalmology & visual science 20100101
Title: Angiotensin II-induced migration of vascular smooth muscle cells is mediated by p38 mitogen-activated protein kinase-activated c-Src through spleen tyrosine kinase and epidermal growth factor receptor transactivation.
Journal: The Journal of pharmacology and experimental therapeutics 20100101
Title: Chemokine receptor CXCR4 enhances proliferation in pancreatic cancer cells through AKT and ERK dependent pathways.
Journal: Pancreas 20100101
Title: Absence of ligand-independent transcriptional activation of the estrogen receptor via the estrogen response element in pituitary lactotrophs in primary culture.
Journal: The Journal of steroid biochemistry and molecular biology 20100101
Title: Prosurvival and proapoptotic functions of ERK1/2 activation in murine thymocytes in vitro.
Journal: Cellular immunology 20100101
Title: Role of angiotensin II in the remodeling induced by a chronic increase in flow in rat mesenteric resistance arteries.
Journal: Hypertension (Dallas, Tex. : 1979) 20100101
Title: Modulation of Akt and ERK1/2 pathways by resveratrol in chronic myelogenous leukemia (CML) cells results in the downregulation of Hsp70.
Journal: PloS one 20100101
Title: The resorcylic acid lactone hypothemycin selectively inhibits the mitogen-activated protein kinase kinase-extracellular signal-regulated kinase pathway in cells.
Journal: Biological & pharmaceutical bulletin 20100101
Title: ER-alpha36, a variant of ER-alpha, promotes tamoxifen agonist action in endometrial cancer cells via the MAPK/ERK and PI3K/Akt pathways.
Journal: PloS one 20100101
Title: Cerebral ischemia induces microvascular pro-inflammatory cytokine expression via the MEK/ERK pathway.
Journal: Journal of neuroinflammation 20100101
Title: Nicotine induces resistance to chemotherapy in nasal epithelial cancer.
Journal: American journal of rhinology & allergy 20100101
Title: alpha-Viniferin suppresses the signal transducer and activation of transcription-1 (STAT-1)-inducible inflammatory genes in interferon-gamma-stimulated macrophages.
Journal: Journal of pharmacological sciences 20100101
Title: gamma-Tocotrienol modulates the paracrine secretion of VEGF induced by cobalt(II) chloride via ERK signaling pathway in gastric adenocarcinoma SGC-7901 cell line.
Journal: Toxicology 20100101
Title: Growth/differentiation factor-5 induces osteogenic differentiation of human ligamentum flavum cells through activation of ERK1/2 and p38 MAPK.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101
Title: Molecular characterization of RsMPK2, a C1 subgroup mitogen-activated protein kinase in the desert plant Reaumuria soongorica.
Journal: Plant physiology and biochemistry : PPB 20100101
Title: Activation of CD147 with cyclophilin a induces the expression of IFITM1 through ERK and PI3K in THP-1 cells.
Journal: Mediators of inflammation 20100101
Title: The serine protease inhibitor serpinE2 is a novel target of ERK signaling involved in human colorectal tumorigenesis.
Journal: Molecular cancer 20100101
Title: Phosphodiesterase 5A inhibition decreases NHE-1 activity without altering steady state pH(i): role of phosphatases.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101
Title: Platelet-activating factor receptor mediates oxidized low density lipoprotein-induced migration of bone marrow-derived mesenchymal stem cells.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101
Title: Induction of glucose metabolism in stimulated T lymphocytes is regulated by mitogen-activated protein kinase signaling.
Journal: PloS one 20100101
Title: Regulation of cell proliferation and apoptosis in neuroblastoma cells by ccp1, a FGF2 downstream gene.
Journal: BMC cancer 20100101
Title: Blocking of ERK1 and ERK2 sensitizes human mesothelioma cells to doxorubicin.
Journal: Molecular cancer 20100101
Title: TGF-β1 induces podocyte injury through Smad3-ERK-NF-κB pathway and Fyn-dependent TRPC6 phosphorylation.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101
Title: Role of the nuclear receptors HNF4 alpha, PPAR alpha, and LXRs in the TNF alpha-mediated inhibition of human apolipoprotein A-I gene expression in HepG2 cells.
Journal: Biochemistry 20091222
Title: Bilateral phosphorylation of ERK in the lateral and centrolateral amygdala during unilateral storage of fear memories.
Journal: Neuroscience 20091215
Title: The effect of linolenic Acid on bovine oocyte maturation and development.
Journal: Biology of reproduction 20091201
Title: O-linked beta-N-acetylglucosaminylation in mouse embryonic neural precursor cells.
Journal: Journal of neuroscience research 20091201
Title: Global effects of kinase inhibitors on signaling networks revealed by quantitative phosphoproteomics.
Journal: Molecular & cellular proteomics : MCP 20091201
Title: Disturbed mitotic progression and genome segregation are involved in cell transformation mediated by nano-TiO2 long-term exposure.
Journal: Toxicology and applied pharmacology 20091201
Title: Extracellular signal regulated kinase 5 mediates signals triggered by the novel tumor promoter palytoxin.
Journal: Toxicology and applied pharmacology 20091201
Title: Stimulation of fibroblast proliferation by the plant cysteine protease CMS2MS2 is independent of its proteolytic activity and requires ERK activation.
Journal: Biological chemistry 20091201
Title: S-Adenosylhomocysteine promotes the invasion of C6 glioma cells via increased secretion of matrix metalloproteinase-2 in murine microglial BV2 cells.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20091201
Title: Differential regulation of human tyrosine hydroxylase isoforms 1 and 2 in situ: Isoform 2 is not phosphorylated at Ser35.
Journal: Biochimica et biophysica acta 20091201
Title: Hypoxia enhances FGF2- and VEGF-stimulated human placental artery endothelial cell proliferation: roles of MEK1/2/ERK1/2 and PI3K/AKT1 pathways.
Journal: Placenta 20091201
Title: Effect of inhibition of extracellular signal-regulated kinase on relaxations to beta-adrenoceptor agonists in porcine isolated blood vessels.
Journal: British journal of pharmacology 20091201
Title: Early changes in Homer1 proteins in the spinal dorsal horn are associated with loose ligation of the rat sciatic nerve.
Journal: Anesthesia and analgesia 20091201
Title: Targeting HER2 signaling pathway for radiosensitization: alternative strategy for therapeutic resistance.
Journal: Cancer biology & therapy 20091201
Title: Oral malodorous compound inhibits osteoblast proliferation.
Journal: Journal of periodontology 20091201
Title: Comparative expression profiling reveals an essential role for raldh2 in epimorphic regeneration.
Journal: The Journal of biological chemistry 20091127
Title: Enterobacter sakazakii targets DC-SIGN to induce immunosuppressive responses in dendritic cells by modulating MAPKs.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20091115
Title: STAT1/2 is involved in the inhibition of cell growth induced by U0126 in HeLa cells.
Journal: Cellular and molecular biology (Noisy-le-Grand, France) 20091115
Title: Novel translational control in Arc-dependent long term potentiation consolidation in vivo.
Journal: The Journal of biological chemistry 20091113
Title: Silibinin prevents TPA-induced MMP-9 expression by down-regulation of COX-2 in human breast cancer cells.
Journal: Journal of ethnopharmacology 20091112
Title: Impaired PTPN13 phosphatase activity in spontaneous or HPV-induced squamous cell carcinomas potentiates oncogene signaling through the MAP kinase pathway.
Journal: Oncogene 20091112
Title: Multiple signaling pathways converge to regulate bone-morphogenetic-protein-dependent glial gene expression.
Journal: Developmental neuroscience 20091101
Title: Involvement of oxidative pathways in cytokine-induced secretory phospholipase A2-IIA in astrocytes.
Journal: Neurochemistry international 20091101
Title: Oligonol, a new lychee fruit-derived low-molecular form of polyphenol, enhances lipolysis in primary rat adipocytes through activation of the ERK1/2 pathway.
Journal: Phytotherapy research : PTR 20091101
Title: GM-CSF regulates the ERK1/2 pathways and protects injured retinal ganglion cells from induced death.
Journal: Experimental eye research 20091101
Title: Constitutive and oxidative-stress-induced expression of VEGF in the RPE are differently regulated by different Mitogen-activated protein kinases.
Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20091101
Title: Fragile X mental retardation protein is required for chemically-induced long-term potentiation of the hippocampus in adult mice.
Journal: Journal of neurochemistry 20091101
Title: Chronic treatment of astrocytes with therapeutically relevant fluoxetine concentrations enhances cPLA2 expression secondary to 5-HT2B-induced, transactivation-mediated ERK1/2 phosphorylation.
Journal: Psychopharmacology 20091101
Title: Deletion of PTEN promotes tumorigenic signaling, resistance to anoikis, and altered response to chemotherapeutic agents in human mammary epithelial cells.
Journal: Cancer research 20091101
Title: Spinal ERK activation via NO-cGMP pathway contributes to nociceptive behavior induced by morphine-3-glucuronide.
Journal: Biochemical pharmacology 20091015
Title: Hydroxylated polychlorinated biphenyls increase reactive oxygen species formation and induce cell death in cultured cerebellar granule cells.
Journal: Toxicology and applied pharmacology 20091015
Title: Tpl2 is a key mediator of arsenite-induced signal transduction.
Journal: Cancer research 20091015
Title: Sodium arsenite-induced DAPK promoter hypermethylation and autophagy via ERK1/2 phosphorylation in human uroepithelial cells.
Journal: Chemico-biological interactions 20091007
Title: Progestin stimulation of manganese superoxide dismutase and invasive properties in T47D human breast cancer cells.
Journal: The Journal of steroid biochemistry and molecular biology 20091001
Title: Down-regulation of HLA Class I and NKG2D ligands through a concerted action of MAPK and DNA methyltransferases in colorectal cancer cells.
Journal: International journal of cancer 20091001
Title: Effects of prostaglandin D2 on Na-dependent phosphate transport activity and its intracellular signaling mechanism in osteoblast-like cells.
Journal: Prostaglandins, leukotrienes, and essential fatty acids 20091001
Title: Lipopolysaccharide directly alters renal tubule transport through distinct TLR4-dependent pathways in basolateral and apical membranes.
Journal: American journal of physiology. Renal physiology 20091001
Title: Lansoprazole, a proton pump inhibitor, mediates anti-inflammatory effect in gastric mucosal cells through the induction of heme oxygenase-1 via activation of NF-E2-related factor 2 and oxidation of kelch-like ECH-associating protein 1.
Journal: The Journal of pharmacology and experimental therapeutics 20091001
Title: FGF-receptor substrate 2 functions as a molecular sensor integrating external regulatory signals into the FGF pathway.
Journal: Cell research 20091001
Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Journal: Nature chemical biology 20091001
Title: Sevoflurane preconditioning induces rapid ischemic tolerance against spinal cord ischemia/reperfusion through activation of extracellular signal-regulated kinase in rabbits.
Journal: Anesthesia and analgesia 20091001
Title: Induction of protection against paraquat-induced oxidative damage by abscisic acid in maize leaves is mediated through mitogen-activated protein kinase.
Journal: Journal of integrative plant biology 20091001
Title: Emodin enhances gefitinib-induced cytotoxicity via Rad51 downregulation and ERK1/2 inactivation.
Journal: Experimental cell research 20090910
Title: The effect of BisGMA on cyclooxygenase-2 expression, PGE2 production and cytotoxicity via reactive oxygen species- and MEK/ERK-dependent and -independent pathways.
Journal: Biomaterials 20090901
Title: Oxidative stress induces anti-hepatitis C virus status via the activation of extracellular signal-regulated kinase.
Journal: Hepatology (Baltimore, Md.) 20090901
Title: Generation of dopamine neurons with improved cell survival and phenotype maintenance using a degradation-resistant nurr1 mutant.
Journal: Stem cells (Dayton, Ohio) 20090901
Title: Platelet-derived growth factor and transforming growth factor-beta modulate the expression of matrix metalloproteinases and migratory function of human airway smooth muscle cells.
Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20090901
Title: TRPC6 up-regulation in Ang II-induced podocyte apoptosis might result from ERK activation and NF-kappaB translocation.
Journal: Experimental biology and medicine (Maywood, N.J.) 20090901
Title: HB-EGF-induced VEGF production and eNOS activation depend on both PI3 kinase and MAP kinase in HaCaT cells.
Journal: Journal of dermatological science 20090901
Title: Inhibition of basal p38 or JNK activity enhances epithelial barrier function through differential modulation of claudin expression.
Journal: American journal of physiology. Cell physiology 20090901
Title: Beta-amyloid monomers are neuroprotective.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090826
Title: Activation of ERK1/2 in the primary injury site is required to maintain melittin-enhanced wind-up of rat spinal wide-dynamic-range neurons.
Journal: Neuroscience letters 20090814
Title: Fluoride-induced cyclooxygenase-2 expression and prostaglandin E2 production in A549 human pulmonary epithelial cells.
Journal: Toxicology letters 20090810
Title: Follistatin, induced by thyrotropin-releasing hormone (TRH), plays no role in prolactin expression but affects gonadotropin FSHbeta expression as a paracrine factor in pituitary somatolactotroph GH3 cells.
Journal: Regulatory peptides 20090807
Title: Simultaneous inhibition of mitogen-activated protein kinase and phosphatidylinositol 3-kinase pathways augment the sensitivity to actinomycin D in Ewing sarcoma.
Journal: Journal of cancer research and clinical oncology 20090801
Title: In vivo and ex vivo regulation of visfatin production by leptin in human and murine adipose tissue: role of mitogen-activated protein kinase and phosphatidylinositol 3-kinase signaling pathways.
Journal: Endocrinology 20090801
Title: Activation of the lutropin/choriogonadotropin receptor inhibits apoptosis of immature Leydig cells in primary culture.
Journal: Endocrinology 20090801
Title: Prolactin induces chitotriosidase expression in human macrophages through PTK, PI3-K, and MAPK pathways.
Journal: Journal of cellular biochemistry 20090801
Title: Silencing TRPM7 promotes growth/proliferation and nitric oxide production of vascular endothelial cells via the ERK pathway.
Journal: Cardiovascular research 20090801
Title: Distinct genetic alterations in the mitogen-activated protein kinase pathway dictate sensitivity of thyroid cancer cells to mitogen-activated protein kinase kinase 1/2 inhibition.
Journal: Thyroid : official journal of the American Thyroid Association 20090801
Title: 20-HETE can act as a nonhypoxic regulator of HIF-1alpha in human microvascular endothelial cells.
Journal: American journal of physiology. Heart and circulatory physiology 20090801
Title: Regulation of collagen turnover in human skin fibroblasts exposed to a gadolinium-based contrast agent.
Journal: Investigative radiology 20090801
Title: [Effect of MAPK signal transduction pathway inhibitor U0126 on aquaporin 4 expression in alveolar type II cells in rats with oleic acid-induced acute lung injury].
Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20090801
Title: Minocycline attenuates both OGD-induced HMGB1 release and HMGB1-induced cell death in ischemic neuronal injury in PC12 cells.
Journal: Biochemical and biophysical research communications 20090724
Title: Interactions of methoxyacetic acid with androgen receptor.
Journal: Toxicology and applied pharmacology 20090715
Title: Extracellular calcium promotes the migration of breast cancer cells through the activation of the calcium sensing receptor.
Journal: Experimental cell research 20090715
Title: Tamoxifen inhibits tumor cell invasion and metastasis in mouse melanoma through suppression of PKC/MEK/ERK and PKC/PI3K/Akt pathways.
Journal: Experimental cell research 20090715
Title: 15-Hydroxyprostaglandin dehydrogenase (15-PGDH) is up-regulated by flurbiprofen and other non-steroidal anti-inflammatory drugs in human colon cancer HT29 cells.
Journal: Archives of biochemistry and biophysics 20090715
Title: TACE-mediated ectodomain shedding of the type I TGF-beta receptor downregulates TGF-beta signaling.
Journal: Molecular cell 20090710
Title: Pre-B cell colony enhancing factor (PBEF)/visfatin induces secretion of MCP-1 in human endothelial cells: role in visfatin-induced angiogenesis.
Journal: Atherosclerosis 20090701
Title: SH2B1beta enhances fibroblast growth factor 1 (FGF1)-induced neurite outgrowth through MEK-ERK1/2-STAT3-Egr1 pathway.
Journal: Cellular signalling 20090701
Title: Mechanisms of protein kinase C signaling in the modulation of 3',5'-cyclic adenosine monophosphate-mediated steroidogenesis in mouse gonadal cells.
Journal: Endocrinology 20090701
Title: Cell death induced by zinc and cadmium is mediated by clusterin in cultured mouse seminiferous tubules.
Journal: Journal of cellular physiology 20090701
Title: 1,4-Diamino-2,3-dicyano-1,4-bis(methylthio)butadiene (U0126) enhances the cytotoxicity of combretastatin A4 independently of mitogen-activated protein kinase kinase.
Journal: The Journal of pharmacology and experimental therapeutics 20090701
Title: Signal transducer and activator of transcription 1 (STAT1) is essential for chromium silencing of gene induction in human airway epithelial cells.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20090701
Title: Elevated hydrostatic pressure activates sodium/hydrogen exchanger-1 in rat optic nerve head astrocytes.
Journal: American journal of physiology. Cell physiology 20090701
Title: Hindlimb unweighting induces changes in the p38MAPK contractile pathway of the rat abdominal aorta.
Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20090701
Title: Foxo3-/- mice demonstrate reduced numbers of pre-B and recirculating B cells but normal splenic B cell sub-population distribution.
Journal: International immunology 20090701
Title: Stimulating the GPR30 estrogen receptor with a novel tamoxifen analogue activates SF-1 and promotes endometrial cell proliferation.
Journal: Cancer research 20090701
Title: Mediobasal hypothalamic leucine sensing regulates food intake through activation of a hypothalamus-brainstem circuit.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090701
Title: Cyclooxygenase-2 up-regulates ataxia telangiectasia and Rad3 related through extracellular signal-regulated kinase activation.
Journal: Molecular cancer research : MCR 20090701
Title: Effects of polychlorinated biphenyls on the neutrophil NADPH oxidase system.
Journal: Toxicology letters 20090622
Title: Ethanol-TGFalpha-MEK signaling promotes growth of human hepatocellular carcinoma.
Journal: The Journal of surgical research 20090615
Title: Activation of ERK and JNK signaling pathways by mycotoxin citrinin in human cells.
Journal: Toxicology and applied pharmacology 20090615
Title: Pharmacologic inhibition of MEK and PI-3K converges on the mTOR/S6 pathway to decelerate cellular senescence.
Journal: Cell cycle (Georgetown, Tex.) 20090615
Title: Biphasic activation of the mTOR pathway in the gustatory cortex is correlated with and necessary for taste learning.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090610
Title: Hydrogen peroxide-induced neuronal apoptosis is associated with inhibition of protein phosphatase 2A and 5, leading to activation of MAPK pathway.
Journal: The international journal of biochemistry & cell biology 20090601
Title: Involvement of protein kinase C signalling and mitogen-activated protein kinase in the amebocyte-producing organ of Biomphalaria glabrata (Mollusca).
Journal: Developmental and comparative immunology 20090601
Title: FGF-1 induces expression of LXRalpha and production of 25-hydroxycholesterol to upregulate the apoE gene in rat astrocytes.
Journal: Journal of lipid research 20090601
Title: Resistance to mitogen-activated protein kinase kinase (MEK) inhibitors correlates with up-regulation of the MEK/extracellular signal-regulated kinase pathway in hepatocellular carcinoma cells.
Journal: The Journal of pharmacology and experimental therapeutics 20090601
Title: The protein synthesis inhibitor anisomycin induces macrophage apoptosis in rabbit atherosclerotic plaques through p38 mitogen-activated protein kinase.
Journal: The Journal of pharmacology and experimental therapeutics 20090601
Title: The free radical scavenger edaravone rescues rats from cerebral infarction by attenuating the release of high-mobility group box-1 in neuronal cells.
Journal: The Journal of pharmacology and experimental therapeutics 20090601
Title: Prenatal ethanol exposure persistently impairs NMDA receptor-dependent activation of extracellular signal-regulated kinase in the mouse dentate gyrus.
Journal: Journal of neurochemistry 20090601
Title: Toll-like receptor signaling in hen ovarian granulosa cells is dependent on stage of follicle maturation.
Journal: Reproduction (Cambridge, England) 20090601
Title: Inhibition of Mek 1/2 kinase activity and stimulation of melanogenesis by 5,7-dimethoxycoumarin treatment of melanoma cells.
Journal: International journal of oncology 20090601
Title: Sustained activation of ERK1/2 by NGF induces microRNA-221 and 222 in PC12 cells.
Journal: The FEBS journal 20090601
Title: Overexpression of thymosin beta4 increases pseudopodia formation in LNCaP prostate cancer cells.
Journal: Biological & pharmaceutical bulletin 20090601
Title: Prolonged withdrawal from repeated noncontingent cocaine exposure increases NMDA receptor expression and ERK activity in the nucleus accumbens.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090527
Title: A role for the extracellular signal-regulated kinase signal pathway in depressive-like behavior.
Journal: Behavioural brain research 20090516
Title: Possible involvement of mitogen-activated protein kinase phosphatase-1 (MKP-1) in thyrotropin-releasing hormone (TRH)-induced prolactin gene expression.
Journal: Biochemical and biophysical research communications 20090515
Title: Influence of progesterone on endometrial nitric oxide synthase expression.
Journal: Fertility and sterility 20090501
Title: Inhibition of MAPK-signaling pathway promotes the interaction of the corepressor SMRT with the human androgen receptor and mediates repression of prostate cancer cell growth in the presence of antiandrogens.
Journal: Journal of molecular endocrinology 20090501
Title: MAPK mediates Hsp25 signaling in incisor development.
Journal: Histochemistry and cell biology 20090501
Title: Involvement of NO and MEK/ERK pathway in enhancement of endothelin-1-induced mesenteric artery contraction in later-stage type 2 diabetic Goto-Kakizaki rat.
Journal: American journal of physiology. Heart and circulatory physiology 20090501
Title: NaF activates MAPKs and induces apoptosis in odontoblast-like cells.
Journal: Journal of dental research 20090501
Title: Simvastatin inhibits induction of matrix metalloproteinase-9 in rat alveolar macrophages exposed to cigarette smoke extract.
Journal: Experimental & molecular medicine 20090430
Title: Phenotype of neurons in the nucleus of the solitary tract that express CCK-induced activation of the ERK signaling pathway.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20090401
Title: Fibrinogen-induced endothelin-1 production from endothelial cells.
Journal: American journal of physiology. Cell physiology 20090401
Title: Tumour necrosis factor alpha stimulates the production of monocyte chemoattractants by extravillous trophoblast cells via differential activation of MAPK pathways.
Journal: Placenta 20090401
Title: Cigarette smoke extract induces cytosolic phospholipase A2 expression via NADPH oxidase, MAPKs, AP-1, and NF-kappaB in human tracheal smooth muscle cells.
Journal: Free radical biology & medicine 20090401
Title: Prostaglandin F(2alpha)-induced interleukin-8 production in human dental pulp cells is associated with MEK/ERK signaling.
Journal: Journal of endodontics 20090401
Title: Tectoridin, a poor ligand of estrogen receptor alpha, exerts its estrogenic effects via an ERK-dependent pathway.
Journal: Molecules and cells 20090331
Title: Amygdala depotentiation ex vivo requires mitogen-activated protein kinases and protein synthesis.
Journal: Neuroreport 20090325
Title: p66Shc links alpha1-adrenergic receptors to a reactive oxygen species-dependent AKT-FOXO3A phosphorylation pathway in cardiomyocytes.
Journal: Circulation research 20090313
Title: Troglitazone increases expression of E-cadherin and claudin 4 in human pancreatic cancer cells.
Journal: Biochemical and biophysical research communications 20090313
Title: Glial fibrillary acidic protein promoter targets pancreatic stellate cells.
Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20090301
Title: The role of p44/42 activation in tributyltin-induced inhibition of human natural killer cells: effects of MEK inhibitors.
Journal: Journal of applied toxicology : JAT 20090301
Title: Nickel compounds induce apoptosis in human bronchial epithelial Beas-2B cells by activation of c-Myc through ERK pathway.
Journal: Toxicology and applied pharmacology 20090301
Title: Cyclic adenosine monophosphate response element-binding protein phosphorylation and neuroprotection by 4-phenyl-1-(4-phenylbutyl) piperidine (PPBP).
Journal: Anesthesia and analgesia 20090301
Title: Diesel exhaust particles activate the matrix-metalloproteinase-1 gene in human bronchial epithelia in a beta-arrestin-dependent manner via activation of RAS.
Journal: Environmental health perspectives 20090301
Title: Role of MAPKs in platinum-induced neuronal apoptosis.
Journal: Neurotoxicology 20090301
Title: Inhibition of benzopyrene-diol-epoxide (BPDE)-induced bax and caspase-9 by cadmium: role of mitogen activated protein kinase.
Journal: Mutation research 20090210
Title: MAPK/ERK1/2 and PI3-kinase signalling pathways are required for vitreous-induced lens fibre cell differentiation.
Journal: Experimental eye research 20090201
Title: Induction of differentiation and mineralization in rat tooth germ cells on PVA through inhibition of ERK1/2.
Journal: Biomaterials 20090201
Title: Dehydroepiandrosterone inhibits CD40/CD40L expression on human umbilical vein endothelial cells induced by interferon gamma.
Journal: International immunopharmacology 20090201
Title: Regulation of genistein-induced differentiation in human acute myeloid leukaemia cells (HL60, NB4) Protein kinase modulation and reactive oxygen species generation.
Journal: Biochemical pharmacology 20090201
Title: trans-Resveratrol inhibits H2O2-induced adenocarcinoma gastric cells proliferation via inactivation of MEK1/2-ERK1/2-c-Jun signalling axis.
Journal: Biochemical pharmacology 20090201
Title: A protein kinase Cdelta-dependent protein kinase D pathway modulates ERK1/2 and JNK1/2 phosphorylation and Bim-associated apoptosis by asbestos.
Journal: The American journal of pathology 20090201
Title: Cyr61 increases migration and MMP-13 expression via alphavbeta3 integrin, FAK, ERK and AP-1-dependent pathway in human chondrosarcoma cells.
Journal: Carcinogenesis 20090201
Title: MAPK-independent impairment of T-cell responses by the multikinase inhibitor sorafenib.
Journal: Molecular cancer therapeutics 20090201
Title: Leukotriene D4 stimulates the migration but not proliferation of endothelial cells mediated by the cysteinyl leukotriene cyslt(1) receptor via the extracellular signal-regulated kinase pathway.
Journal: Journal of pharmacological sciences 20090201
Title: Protective effects of asiatic acid against D-galactosamine/lipopolysaccharide-induced hepatotoxicity in hepatocytes and kupffer cells co-cultured system via redox-regulated leukotriene C4 synthase expression pathway.
Journal: European journal of pharmacology 20090128
Title: Mitogen-activated protein kinase-signaling stimulates Müller glia to proliferate in acutely damaged chicken retina.
Journal: Glia 20090115
Title: Ascorbic acid 6-palmitate suppresses gap-junctional intercellular communication through phosphorylation of connexin 43 via activation of the MEK-ERK pathway.
Journal: Mutation research 20090115
Title: Ischemic postconditioning in pigs: no causal role for RISK activation.
Journal: Circulation research 20090102
Title: hsBAFF-upregulated intracellular free Ca(2+) homeostasis regulates ERK1/2 activity and cell proliferation in B cells in vitro.
Journal: Physiological research 20090101
Title: Angiotensin II stimulates water and NaCl intake through separate cell signalling pathways in rats.
Journal: Experimental physiology 20090101
Title: Organochlorine-mediated potentiation of the general coactivator p300 through p38 mitogen-activated protein kinase.
Journal: Carcinogenesis 20090101
Title: TLR-4 agonistic lipopolysaccharide upregulates interleukin-8 at the transcriptional and post-translational level in vascular smooth muscle cells.
Journal: Vascular pharmacology 20090101
Title: Ethanol attenuates the HFS-induced, ERK-mediated LTP in a dose-dependent manner in rat striatum.
Journal: Alcoholism, clinical and experimental research 20090101
Title: Bile acids activate fibroblast growth factor 19 signaling in human hepatocytes to inhibit cholesterol 7alpha-hydroxylase gene expression.
Journal: Hepatology (Baltimore, Md.) 20090101
Title: Neuronal injury induces cytokine-induced neutrophil chemoattractant-1 (CINC-1) production in astrocytes.
Journal: Journal of pharmacological sciences 20090101
Title: Apoptosis induction by oxidized glycated LDL in human retinal capillary pericytes is independent of activation of MAPK signaling pathways.
Journal: Molecular vision 20090101
Title: Calcitonin gene-related peptide stimulates proliferation of alveolar epithelial cells.
Journal: Respiratory research 20090101
Title: DY-9760e inhibits endothelin-1-induced cardiomyocyte hypertrophy through inhibition of CaMKII and ERK activities.
Journal: Cardiovascular therapeutics 20090101
Title: Urocortin II induces nitric oxide production through cAMP and Ca2+ related pathways in endothelial cells.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20090101
Title: Effect of inhibitors of mitogen-activated protein kinase kinase on alpha(1B)-adrenoceptor phosphorylation.
Journal: Autonomic & autacoid pharmacology 20090101
Title: Retinal regeneration in the Xenopus laevis tadpole: a new model system.
Journal: Molecular vision 20090101
Title: Enhanced cerebrovascular expression of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 via the MEK/ERK pathway during cerebral ischemia in the rat.
Journal: BMC neuroscience 20090101
Title: Presence and regulation of cannabinoid receptors in human retinal pigment epithelial cells.
Journal: Molecular vision 20090101
Title: Leptin stimulated C-reactive protein production by human coronary artery endothelial cells.
Journal: Journal of vascular research 20090101
Title: The proliferation and migration effects of huangqi on RSC96 Schwann cells.
Journal: The American journal of Chinese medicine 20090101
Title: Effects of 15-deoxy-delta12,14-prostaglandin J2 (15d-PGJ2) and rosiglitazone on human gammadelta2 T cells.
Journal: PloS one 20090101
Title: Non-receptor tyrosine kinase Src is required for ischemia-stimulated neuronal cell proliferation via Raf/ERK/CREB activation in the dentate gyrus.
Journal: BMC neuroscience 20090101
Title: The obesity and inflammatory marker haptoglobin attracts monocytes via interaction with chemokine (C-C motif) receptor 2 (CCR2).
Journal: BMC biology 20090101
Title: Lysophosphatidic acid receptor 2 and Gi/Src pathway mediate cell motility through cyclooxygenase 2 expression in CAOV-3 ovarian cancer cells.
Journal: Experimental & molecular medicine 20081231
Title: Human EP3(I) prostanoid receptor induces VEGF and VEGF receptor-1 mRNA expression.
Journal: Biochemical and biophysical research communications 20081226
Title: Cardiotrophin-1 induces intercellular adhesion molecule-1 expression by nuclear factor kappaB activation in human umbilical vein endothelial cells.
Journal: Chinese medical journal 20081220
Title: Nifuroxazide inhibits survival of multiple myeloma cells by directly inhibiting STAT3.
Journal: Blood 20081215
Title: PAR2 triggers IL-8 release via MEK/ERK and PI3-kinase/Akt pathways in GI epithelial cells.
Journal: Biochemical and biophysical research communications 20081212
Title: Central amygdala extracellular signal-regulated kinase signaling pathway is critical to incubation of opiate craving.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20081203
Title: The effect of doxorubicin on MEK-ERK signaling predicts its efficacy in HCC.
Journal: The Journal of surgical research 20081201
Title: Sorafenib triggers antiproliferative and pro-apoptotic signals in human esophageal adenocarcinoma cells.
Journal: Digestive diseases and sciences 20081201
Title: The effect of serotonin on GABA synthesis in cultured rat spinal dorsal horn neurons.
Journal: Journal of chemical neuroanatomy 20081201
Title: Lipid-soluble smoke particles upregulate vascular smooth muscle ETB receptors via activation of mitogen-activating protein kinases and NF-kappaB pathways.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20081201
Title: Fluoxetine-mediated 5-HT2B receptor stimulation in astrocytes causes EGF receptor transactivation and ERK phosphorylation.
Journal: Psychopharmacology 20081201
Title: Nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induce cyclooxygenase-2 activity in human gastric cancer cells: Involvement of nicotinic acetylcholine receptor (nAChR) and beta-adrenergic receptor signaling pathways.
Journal: Toxicology and applied pharmacology 20081201
Title: Phosphorylation of TRPV1 by neurokinin-1 receptor agonist exaggerates the capsaicin-mediated substance P release from cultured rat dorsal root ganglion neurons.
Journal: Neuropharmacology 20081201
Title: Arsenic trioxide phosphorylates c-Fos to transactivate p21(WAF1/CIP1) expression.
Journal: Toxicology and applied pharmacology 20081201
Title: Regulation of ACE2 in cardiac myocytes and fibroblasts.
Journal: American journal of physiology. Heart and circulatory physiology 20081201
Title: Astrocytic proliferation and mitochondrial dysfunction induced by accumulated glutaric acidemia I (GAI) metabolites: possible implications for GAI pathogenesis.
Journal: Neurobiology of disease 20081201
Title: Phosphatidylinositol acts through mitogen-activated protein kinase to stimulate hepatic apolipoprotein A-I secretion.
Journal: Metabolism: clinical and experimental 20081201
Title: Simultaneous stimulation of spinal NK1 and NMDA receptors produces LPC which undergoes ATX-mediated conversion to LPA, an initiator of neuropathic pain.
Journal: Journal of neurochemistry 20081201
Title: Arsenic trioxide (As2O3) inhibits expression of estrogen receptor-alpha through regulation of the mitogen-activated protein kinase (MAPK) pathway in endometrial cancer cells.
Journal: Reproductive sciences (Thousand Oaks, Calif.) 20081201
Title: Rapamycin inhibits growth factor-induced cell cycle regulation in pancreatic beta cells.
Journal: Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20081201
Title: Aldosterone induces collagen synthesis via activation of extracellular signal-regulated kinase 1 and 2 in renal proximal tubules.
Journal: Nephrology (Carlton, Vic.) 20081201
Title: Reciprocal influences of CB1 cannabinoid receptor agonists on ERK and JNK signalling in N1E-115 cells.
Journal: FEBS letters 20081126
Title: Extracellular signal-regulated kinases mediate melittin-induced hypersensitivity of spinal neurons to chemical and thermal but not mechanical stimuli.
Journal: Brain research bulletin 20081125
Title: Cross-talk between MEK1/2-ERK1/2 signaling and G protein-couple signaling in synoviocytes of collagen-induced arthritis rats.
Journal: Chinese medical journal 20081120
Title: Effects and mechanism of glucagon-like peptide-1 on injury of rats cardiomyocytes induced by hypoxia-reoxygenation.
Journal: Chinese medical journal 20081105
Title: Egr-1 mRNA induction by medium flow involves mRNA stabilization and is enhanced by the p38 inhibitor SB203580 in osteoblast-like cells.
Journal: Acta physiologica (Oxford, England) 20081101
Title: Testosterone potentially triggers meiotic resumption by activation of intra-oocyte SRC and MAPK in porcine oocytes.
Journal: Biology of reproduction 20081101
Title: PAR2 exerts local protection against acute pancreatitis via modulation of MAP kinase and MAP kinase phosphatase signaling.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20081101
Title: ERKs/p53 signal transduction pathway is involved in doxorubicin-induced apoptosis in H9c2 cells and cardiomyocytes.
Journal: American journal of physiology. Heart and circulatory physiology 20081101
Title: Leishmania donovani infection down-regulates TLR2-stimulated IL-12p40 and activates IL-10 in cells of macrophage/monocytic lineage by modulating MAPK pathways through a contact-dependent mechanism.
Journal: Clinical and experimental immunology 20081101
Title: Activation of peripheral ephrinBs/EphBs signaling induces hyperalgesia through a MAPKs-mediated mechanism in mice.
Journal: Pain 20081031
Title: Neuronal activity and TrkB ligands influence Kv3.1b and Kv3.2 expression in developing cortical interneurons.
Journal: Neuroscience 20081015
Title: Curcumin attenuates EGF-induced AQP3 up-regulation and cell migration in human ovarian cancer cells.
Journal: Cancer chemotherapy and pharmacology 20081001
Title: MEK1/2 is a critical regulator of microtubule assembly and spindle organization during rat oocyte meiotic maturation.
Journal: Molecular reproduction and development 20081001
Title: Extracellular signal-regulated kinase-dependent interstitial macrophage proliferation in the obstructed mouse kidney.
Journal: Nephrology (Carlton, Vic.) 20081001
Title: Haem oxygenase-1 plays a central role in NNK-mediated lung carcinogenesis.
Journal: The European respiratory journal 20081001
Title: E series of prostaglandin receptor 2-mediated activation of extracellular signal-regulated kinase/activator protein-1 signaling is required for the mitogenic action of prostaglandin E2 in esophageal squamous-cell carcinoma.
Journal: The Journal of pharmacology and experimental therapeutics 20081001
Title: Keratinocyte-derived vascular endothelial growth factor biosynthesis represents a pleiotropic side effect of peroxisome proliferator-activated receptor-gamma agonist troglitazone but not rosiglitazone and involves activation of p38 mitogen-activated protein kinase: implications for diabetes-impaired skin repair.
Journal: Molecular pharmacology 20081001
Title: Inhibition of Aurora-A suppresses epithelial-mesenchymal transition and invasion by downregulating MAPK in nasopharyngeal carcinoma cells.
Journal: Carcinogenesis 20081001
Title: Cadmium activates the mitogen-activated protein kinase (MAPK) pathway via induction of reactive oxygen species and inhibition of protein phosphatases 2A and 5.
Journal: Free radical biology & medicine 20081001
Title: Effects of downregulated HDAC6 expression on the proliferation of lung cancer cells.
Journal: Biochemical and biophysical research communications 20080912
Title: A role for the aryl hydrocarbon receptor and the dioxin TCDD in rheumatoid arthritis.
Journal: Rheumatology (Oxford, England) 20080901
Title: Down-regulation of the PI3-kinase/Akt pathway by ERK MAP kinase in growth factor signaling.
Journal: Genes to cells : devoted to molecular & cellular mechanisms 20080901
Title: Effect of chemotherapeutic stress on induction of vascular endothelial growth factor family members and receptors in human colorectal cancer cells.
Journal: Molecular cancer therapeutics 20080901
Title: MEK-inhibitor U0126 in hyperglycaemic focal ischaemic brain injury in the rat.
Journal: European journal of clinical investigation 20080901
Title: Circadian oscillation of hippocampal MAPK activity and cAmp: implications for memory persistence.
Journal: Nature neuroscience 20080901
Title: Hypo-responsiveness of interleukin-8 production in human embryonic epithelial intestine 407 cells independent of NF-kappaB pathway: new lessons from endotoxin and ribotoxic deoxynivalenol.
Journal: Toxicology and applied pharmacology 20080815
Title: Mitochondrial membrane potential in axons increases with local nerve growth factor or semaphorin signaling.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080813
Title: IGF-I protects human oral buccal mucosal epithelial cells from sodium nitroprusside-induced apoptosis via PI3-kinase.
Journal: Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 20080801
Title: Combined inhibition of MAPK and mTOR signaling inhibits growth, induces cell death, and abrogates invasive growth of melanoma cells.
Journal: The Journal of investigative dermatology 20080801
Title: The novel adipocytokine visfatin exerts direct cardioprotective effects.
Journal: Journal of cellular and molecular medicine 20080801
Title: Ethanol inhibition of angiotensin II-stimulated Tyr705 and Ser727 STAT3 phosphorylation in cultured rat hepatocytes: relevance to activation of p42/44 mitogen-activated protein kinase.
Journal: Alcohol (Fayetteville, N.Y.) 20080801
Title: Rapid activation of Stat3 and ERK1/2 by nicotine modulates cell proliferation in human bladder cancer cells.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20080801
Title: Retinoic acid induces apoptosis by a non-classical mechanism of ERK1/2 activation.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20080801
Title: Tumour-mediated disruption of dendritic cell function: inhibiting the MEK1/2-p44/42 axis restores IL-12 production and Th1-generation.
Journal: International journal of cancer 20080801
Title: Angiotensin II type 1 receptor signaling contributes to synaptophysin degradation and neuronal dysfunction in the diabetic retina.
Journal: Diabetes 20080801
Title: Characterization of early events involved in human dendritic cell maturation induced by sensitizers: cross talk between MAPK signalling pathways.
Journal: Toxicology and applied pharmacology 20080801
Title: Somatostatin inhibits hepatic growth hormone receptor and insulin-like growth factor I mRNA expression by activating the ERK and PI3K signaling pathways.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20080801
Title: AMPK activator, AICAR, inhibits palmitate-induced apoptosis in osteoblast.
Journal: Bone 20080801
Title: Regulation of myosin light chain kinase expression by angiotensin II in hypertension.
Journal: American journal of hypertension 20080801
Title: Fluoxetine-induced proliferation and differentiation of neural progenitor cells isolated from rat postnatal cerebellum.
Journal: Biochemical pharmacology 20080801
Title: Flagellin and lipopolysaccharide up-regulation of IL-6 and CXCLi2 gene expression in chicken heterophils is mediated by ERK1/2-dependent activation of AP-1 and NF-kappaB signaling pathways.
Journal: Innate immunity 20080801
Title: Fibroblast growth factor-2 and -4 promote the proliferation of bone marrow mesenchymal stem cells by the activation of the PI3K-Akt and ERK1/2 signaling pathways.
Journal: Stem cells and development 20080801
Title: Lumican induces human corneal epithelial cell migration and integrin expression via ERK 1/2 signaling.
Journal: Biochemical and biophysical research communications 20080718
Title: Cytoprotective effect of tauroursodeoxycholate on hepatocyte apoptosis induced by peroxisome proliferator-activated receptor gamma ligand.
Journal: Journal of gastroenterology and hepatology 20080701
Title: Epithelial sodium channel is a key mediator of growth hormone-induced sodium retention in acromegaly.
Journal: Endocrinology 20080701
Title: Oxidative stress regulates type 3 deiodinase and type 2 deiodinase in cultured rat astrocytes.
Journal: Endocrinology 20080701
Title: Inflammatory levels of nitric oxide inhibit airway epithelial cell migration by inhibition of the kinase ERK1/2 and activation of hypoxia-inducible factor-1 alpha.
Journal: The Journal of biological chemistry 20080627
Title: A positive feedback pathway of estrogen biosynthesis in breast cancer cells is contained by resveratrol.
Journal: Toxicology 20080627
Title: MEK inhibitor enhances the inhibitory effect of imatinib on pancreatic cancer cell growth.
Journal: Cancer letters 20080618
Title: Kaempferol and quercetin stimulate granulocyte-macrophage colony-stimulating factor secretion in human prostate cancer cells.
Journal: Molecular and cellular endocrinology 20080611
Title: Stimulation by vasopressin of ERK phosphorylation and vector-driven water flux in astrocytes is transactivation-dependent.
Journal: European journal of pharmacology 20080610
Title: A23187, ionomycin and thapsigargin upregulate mRNA of HIF-1alpha via endoplasmic reticulum stress rather than a rise in intracellular calcium.
Journal: Journal of cellular physiology 20080601
Title: Retinoid X receptor alpha is highly phosphorylated in retinoic acid-resistant HL-60R cells and the combination of 9-cis retinoic acid plus MEK inhibitor induces apoptosis in the cells.
Journal: Leukemia research 20080601
Title: Cyst formation and activation of the extracellular regulated kinase pathway after kidney specific inactivation of Pkd1.
Journal: Human molecular genetics 20080601
Title: Cyclosporin A promotes growth and invasiveness in vitro of human first-trimester trophoblast cells via MAPK3/MAPK1-mediated AP1 and Ca2+/calcineurin/NFAT signaling pathways.
Journal: Biology of reproduction 20080601
Title: Role for inhibitor of differentiation/deoxyribonucleic acid-binding (Id) proteins in granulosa cell differentiation.
Journal: Endocrinology 20080601
Title: Prolonged heterologous beta2-adrenoceptor desensitization promotes proasthmatic airway smooth muscle function via PKA/ERK1/2-mediated phosphodiesterase-4 induction.
Journal: American journal of physiology. Lung cellular and molecular physiology 20080601
Title: Prevotella intermedia induces matrix metalloproteinase-9 expression in human periodontal ligament cells.
Journal: FEMS microbiology letters 20080601
Title: Octylphenol stimulates resistin gene expression in 3T3-L1 adipocytes via the estrogen receptor and extracellular signal-regulated kinase pathways.
Journal: American journal of physiology. Cell physiology 20080601
Title: Coordinated phosphorylation of insulin receptor substrate-1 by glycogen synthase kinase-3 and protein kinase C betaII in the diabetic fat tissue.
Journal: American journal of physiology. Endocrinology and metabolism 20080601
Title: Intracellular signal transduction by the extracellular calcium-sensing receptor of Xenopus melanotrope cells.
Journal: General and comparative endocrinology 20080601
Title: Activation of exchange protein activated by cyclic-AMP enhances long-lasting synaptic potentiation in the hippocampus.
Journal: Learning & memory (Cold Spring Harbor, N.Y.) 20080601
Title: Differential contribution of spinal mitogen-activated protein kinases to the phase of long-lasting allodynia evoked by intrathecal administration of ATP in rats.
Journal: Biological & pharmaceutical bulletin 20080601
Title: Pharmacological inhibitors of JNK and ERK kinases SP600125 and U0126 are not appropriate tools for studies of drug metabolism because they activate aryl hydrocarbon receptor.
Journal: General physiology and biophysics 20080601
Title: Involvement of NF-kappaB and AP-1 activation in icariin promoted cardiac differentiation of mouse embryonic stem cells.
Journal: European journal of pharmacology 20080531
Title: Growth factor-induced phosphorylation of sterol regulatory element-binding proteins inhibits sumoylation, thereby stimulating the expression of their target genes, low density lipoprotein uptake, and lipid synthesis.
Journal: The Journal of biological chemistry 20080530
Title: Activation of TRPV1 contributes to morphine tolerance: involvement of the mitogen-activated protein kinase signaling pathway.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080528
Title: ETOH inhibits embryonic neural stem/precursor cell proliferation via PLD signaling.
Journal: Biochemical and biophysical research communications 20080523
Title: Regulation of arsenic trioxide-induced cellular responses by Mnk1 and Mnk2.
Journal: The Journal of biological chemistry 20080502
Title: PI3-kinase and mitogen-activated protein kinase in cumulus cells mediate EGF-induced meiotic resumption of porcine oocyte.
Journal: Domestic animal endocrinology 20080501
Title: Bim, Bak, and Bax regulate osteoblast survival.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20080501
Title: Activation of spinal ERK signaling pathway contributes to pain-related responses induced by scorpion Buthus martensi Karch venom.
Journal: Toxicon : official journal of the International Society on Toxinology 20080501
Title: Growth hormone-mediated survival of embryonic retinal ganglion cells: signaling mechanisms.
Journal: General and comparative endocrinology 20080501
Title: Extracellular signal-regulated kinase (ERK) and protein kinase B (AKT) pathways involved in spinal cord stimulation (SCS)-induced vasodilation.
Journal: Brain research 20080501
Title: Protein kinase A-mediated CREB phosphorylation is an oxidant-induced survival pathway in alveolar type II cells.
Journal: Apoptosis : an international journal on programmed cell death 20080501
Title: In vitro, inhibition of mitogen-activated protein kinase pathways protects against bupivacaine- and ropivacaine-induced neurotoxicity.
Journal: Anesthesia and analgesia 20080501
Title: Potential role of phospholipase D2 in increasing interleukin-2 production by T-lymphocytes through activation of mitogen-activated protein kinases ERK1/ERK2.
Journal: Biochimica et biophysica acta 20080501
Title: Constitutive activation of p70 S6 kinase is associated with intrinsic resistance to cisplatin.
Journal: International journal of oncology 20080501
Title: Receptor-mediated tobacco toxicity: acceleration of sequential expression of alpha5 and alpha7 nicotinic receptor subunits in oral keratinocytes exposed to cigarette smoke.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080501
Title: Enzyme kinetics and binding studies on inhibitors of MEK protein kinase.
Journal: Biochemistry 20080429
Title: Involvement of mitogen-activated protein kinases and NFkappaB in LPS-induced CD40 expression on human monocytic cells.
Journal: Toxicology and applied pharmacology 20080415
Title: RB status governs differential sensitivity to cytotoxic and molecularly-targeted therapeutic agents.
Journal: Cell cycle (Georgetown, Tex.) 20080415
Title: Terrein inhibits keratinocyte proliferation via ERK inactivation and G2/M cell cycle arrest.
Journal: Experimental dermatology 20080401
Title: MAPK and mTOR pathways are involved in cadmium-induced neuronal apoptosis.
Journal: Journal of neurochemistry 20080401
Title: Atorvastatin induces apoptosis by a caspase-9-dependent pathway: an in vitro study on activated rat hepatic stellate cells.
Journal: Liver international : official journal of the International Association for the Study of the Liver 20080401
Title: Phosphorylation at serines 104 and 106 by Erk1/2 MAPK is important for estrogen receptor-alpha activity.
Journal: Journal of molecular endocrinology 20080401
Title: Neuroplasticity in brain reward circuitry following a history of ethanol dependence.
Journal: The European journal of neuroscience 20080401
Title: Growth compensatory role of sulindac sulfide-induced thrombospondin-1 linked with ERK1/2 and RhoA GTPase signaling pathways.
Journal: Life sciences 20080312
Title: Inhibition of benzopyrene diol epoxide-induced apoptosis by cadmium(II) is AP-1-independent: role of extracelluler signal related kinase.
Journal: Chemico-biological interactions 20080310
Title: RhoA prevents apoptosis during zebrafish embryogenesis through activation of Mek/Erk pathway.
Journal: Oncogene 20080306
Title: Depolarization-induced differentiation of PC12 cells is mediated by phospholipase D2 through the transcription factor CREB pathway.
Journal: Journal of neurochemistry 20080301
Title: The role of redox-sensitive transcription factors NF-kappaB and AP-1 in the modulation of the Cyp1a1 gene by mercury, lead, and copper.
Journal: Free radical biology & medicine 20080301
Title: Roles of Rho guanosine 5'-triphosphatase A, Rho kinases, and extracellular signal regulated kinase (1/2) in prostaglandin E2-mediated migration of first-trimester human extravillous trophoblast.
Journal: Endocrinology 20080301
Title: Targeting 14-3-3 sensitizes native and mutant BCR-ABL to inhibition with U0126, rapamycin and Bcl-2 inhibitor GX15-070.
Journal: Leukemia 20080301
Title: Inhibition of Src and p38 MAP kinases suppresses the change of claudin expression induced on dedifferentiation of primary cultured parotid acinar cells.
Journal: American journal of physiology. Cell physiology 20080301
Title: p21 Waf1/Cip1 expression by curcumin in U-87MG human glioma cells: role of early growth response-1 expression.
Journal: Cancer research 20080301
Title: Stress-activated protein kinase inhibition to ameliorate lung ischemia reperfusion injury.
Journal: The Journal of thoracic and cardiovascular surgery 20080301
Title: Mechanisms for the proliferation of eosinophilic leukemia cells by FIP1L1-PDGFRalpha.
Journal: Biochemical and biophysical research communications 20080222
Title: Suppression of v-Src transformation by andrographolide via degradation of the v-Src protein and attenuation of the Erk signaling pathway.
Journal: The Journal of biological chemistry 20080222
Title: Ebselen, a redox regulator containing a selenium atom, induces neurofilament M expression in cultured rat pheochromocytoma PC12 cells via activation of mitogen-activated protein kinase.
Journal: Journal of neuroscience research 20080215
Title: Lipolysis is stimulated by PEGylated conjugated linoleic acid through the cyclic adenosine monophosphate-independent signaling pathway in 3T3-L1 cells: activation of MEK/ERK MAPK signaling pathway and hyper-secretion of adipo-cytokines.
Journal: Journal of cellular physiology 20080201
Title: Toll-like receptor agonists stimulate human neutrophil migration via activation of mitogen-activated protein kinases.
Journal: Immunology 20080201
Title: Spatio-temporal expression patterns of aurora kinases a, B, and C and cytoplasmic polyadenylation-element-binding protein in bovine oocytes during meiotic maturation.
Journal: Biology of reproduction 20080201
Title: Gremlin-mediated decrease in bone morphogenetic protein signaling promotes pulmonary fibrosis.
Journal: American journal of respiratory and critical care medicine 20080201
Title: Tuberin-heterozygous cell line TSC2ang1 as a model for tuberous sclerosis-associated skin lesions.
Journal: International journal of molecular medicine 20080201
Title: Release of heat shock proteins from human neuroblastoma cells exposed to acrylamide.
Journal: The Journal of toxicological sciences 20080201
Title: Nobiletin, a citrus flavonoid with neurotrophic action, augments protein kinase A-mediated phosphorylation of the AMPA receptor subunit, GluR1, and the postsynaptic receptor response to glutamate in murine hippocampus.
Journal: European journal of pharmacology 20080114
Title: Ribotoxic mycotoxin deoxynivalenol induces G2/M cell cycle arrest via p21Cip/WAF1 mRNA stabilization in human epithelial cells.
Journal: Toxicology 20080114
Title: Extracellular calcium-sensing receptor activation induces vitamin D receptor levels in proximal kidney HK-2G cells by a mechanism that requires phosphorylation of p38alpha MAPK.
Journal: The Journal of biological chemistry 20080104
Title: Involvement of the ERK1/2 MAPK pathway in insulin-induced S6K1 activation in avian cells.
Journal: Domestic animal endocrinology 20080101
Title: Evidence that PAR2-triggered prostaglandin E2 (PGE2) formation involves the ERK-cytosolic phospholipase A2-COX-1-microsomal PGE synthase-1 cascade in human lung epithelial cells.
Journal: Cell biochemistry and function 20080101
Title: Rapid activation of ERK by 6-hydroxydopamine promotes survival of dopaminergic cells.
Journal: Journal of neuroscience research 20080101
Title: Nitrogen-containing bisphosphonate, YM529/ONO-5920, inhibits macrophage inflammatory protein 1 alpha expression and secretion in mouse myeloma cells.
Journal: Cancer science 20080101
Title: Glycogen synthase kinases 3alpha and 3beta in cardiac myocytes: regulation and consequences of their inhibition.
Journal: Cellular signalling 20080101
Title: delta-Opioid receptor stimulation enhances the growth of neonatal rat ventricular myocytes via the extracellular signal-regulated kinase pathway.
Journal: Clinical and experimental pharmacology & physiology 20080101
Title: TLQP-21, a neuroendocrine VGF-derived peptide, prevents cerebellar granule cells death induced by serum and potassium deprivation.
Journal: Journal of neurochemistry 20080101
Title: [Fluvastatin induces apoptosis on human tongue carcinoma cell line HSC-3].
Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20080101
Title: Visible light modulates the expression of cancer-retina antigens.
Journal: Molecular cancer research : MCR 20080101
Title: Roles of MAPK and NF-kappaB in interleukin-6 induction by lipopolysaccharide in vascular smooth muscle cells.
Journal: Journal of cardiovascular pharmacology 20080101
Title: Down-regulation of mcl-1 by small interfering RNA sensitizes resistant melanoma cells to fas-mediated apoptosis.
Journal: Molecular cancer research : MCR 20080101
Title: Differential roles of basolateral and central amygdala on the effects of uncontrollable stress on hippocampal synaptic plasticity.
Journal: Hippocampus 20080101
Title: FGF2 signaling in mouse embryonic fibroblasts is crucial for self-renewal of embryonic stem cells.
Journal: Cells, tissues, organs 20080101
Title: Use of Caenorhabditis elegans to evaluate inhibitors of Ras function in vivo.
Journal: Methods in enzymology 20080101
Title: The small molecule Mek1/2 inhibitor U0126 disrupts the chordamesoderm to notochord transition in zebrafish.
Journal: BMC developmental biology 20080101
Title: Protein kinase C beta overexpression induces fibrotic effects in human proximal tubular epithelial cells.
Journal: The international journal of biochemistry & cell biology 20080101
Title: Differential activation of p38 and extracellular signal-regulated kinase in spinal cord in a model of bee venom-induced inflammation and hyperalgesia.
Journal: Molecular pain 20080101
Title: Hemispheric lateralization of a molecular signal for pain modulation in the amygdala.
Journal: Molecular pain 20080101
Title: PKA and ERK, but not PKC, in the amygdala contribute to pain-related synaptic plasticity and behavior.
Journal: Molecular pain 20080101
Title: NF-kappaB and AP-1 are key signaling pathways in the modulation of NAD(P)H:quinone oxidoreductase 1 gene by mercury, lead, and copper.
Journal: Journal of biochemical and molecular toxicology 20080101
Title: Enhanced expressions of microvascular smooth muscle receptors after focal cerebral ischemia occur via the MAPK MEK/ERK pathway.
Journal: BMC neuroscience 20080101
Title: Regulation of GCL activity and cellular glutathione through inhibition of ERK phosphorylation.
Journal: BioFactors (Oxford, England) 20080101
Title: A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20071218
Title: The selectivity of protein kinase inhibitors: a further update.
Journal: The Biochemical journal 20071215
Title: Insulin rescues ES cell-derived neural progenitor cells from apoptosis by differential regulation of Akt and ERK pathways.
Journal: Neuroscience letters 20071211
Title: Differentiation of gastric surface mucous cells (GSM06) induced by air-liquid interface is regulated partly through mitogen-activated protein kinase pathway.
Journal: Journal of gastroenterology and hepatology 20071201
Title: Basolateral amygdala inactivation by muscimol, but not ERK/MAPK inhibition, impairs the use of reward expectancies during working memory.
Journal: The European journal of neuroscience 20071201
Title: Reversal of the estrogen receptor negative phenotype in breast cancer and restoration of antiestrogen response.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20071201
Title: The cannabinoid delta(9)-tetrahydrocannabinol inhibits RAS-MAPK and PI3K-AKT survival signalling and induces BAD-mediated apoptosis in colorectal cancer cells.
Journal: International journal of cancer 20071115
Title: Leptin stimulates endothelin-1 expression via extracellular signal-regulated kinase by epidermal growth factor receptor transactivation in rat aortic smooth muscle cells.
Journal: European journal of pharmacology 20071114
Title: Involvement of ERK signaling in halofuginone-driven inhibition of fibroblast ability to contract collagen lattices.
Journal: European journal of pharmacology 20071114
Title: Glutathione depletion activates mitogen-activated protein kinase (MAPK) pathways that display organ-specific responses and brain protection in mice.
Journal: Free radical biology & medicine 20071101
Title: Prostaglandin E2 induces hypertrophic changes and suppresses alpha-skeletal actin gene expression in rat cardiomyocytes.
Journal: Journal of cardiovascular pharmacology 20071101
Title: Modulation of Ca2+ transients in cultured endothelial cells in response to fluid flow through alphav integrin.
Journal: Life sciences 20071027
Title: STAT3-dependent mouse embryonic stem cell differentiation into cardiomyocytes: analysis of molecular signaling and therapeutic efficacy of cardiomyocyte precommitted mES transplantation in a mouse model of myocardial infarction.
Journal: Circulation research 20071026
Title: Mixed lineage kinase 3 connects reactive oxygen species to c-Jun NH2-terminal kinase-induced mitochondrial apoptosis in genipin-treated PC3 human prostate cancer cells.
Journal: Biochemical and biophysical research communications 20071019
Title: Activated macrophages in HIV encephalitis and a macaque model show increased [3H](R)-PK11195 binding in a PI3-kinase-dependent manner.
Journal: Neuroscience letters 20071016
Title: Prevention of LLC-PK(1) cell overgrowth in a bioartificial renal tubule device using a MEK inhibitor, U0126.
Journal: Journal of biotechnology 20071015
Title: Inhibition of MEK sensitizes human melanoma cells to endoplasmic reticulum stress-induced apoptosis.
Journal: Cancer research 20071015
Title: Ascochlorin suppresses oxLDL-induced MMP-9 expression by inhibiting the MEK/ERK signaling pathway in human THP-1 macrophages.
Journal: Journal of cellular biochemistry 20071001
Title: Regulation of matrix Gla protein by parathyroid hormone in MC3T3-E1 osteoblast-like cells involves protein kinase A and extracellular signal-regulated kinase pathways.
Journal: Journal of cellular biochemistry 20071001
Title: Regulation of interleukin-8 expression in human prostate cancer cells by insulin-like growth factor-I and inflammatory cytokines.
Journal: Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 20071001
Title: Macrophage inflammatory protein-1alpha (MIP-1alpha) enhances a receptor activator of nuclear factor kappaB ligand (RANKL) expression in mouse bone marrow stromal cells and osteoblasts through MAPK and PI3K/Akt pathways.
Journal: Molecular and cellular biochemistry 20071001
Title: Modulation of mast cell proteinase-activated receptor expression and IL-4 release by IL-12.
Journal: Immunology and cell biology 20071001
Title: MCI-186 prevents brain tissue from neuronal damage in cerebral infarction through the activation of intracellular signaling.
Journal: Journal of neuroscience research 20071001
Title: Regulation of C-C motif chemokine ligand 2 and its receptor in human decidual stromal cells by pregnancy-associated hormones in early gestation.
Journal: Human reproduction (Oxford, England) 20071001
Title: Manganese chloride stimulates rat microglia to release hydrogen peroxide.
Journal: Toxicology letters 20070910
Title: Mechanism for FGF-1 to regulate biogenesis of apoE-HDL in astrocytes.
Journal: Journal of lipid research 20070901
Title: Possible role of 5'AMP-activated protein kinase in the metformin-mediated arrest of bovine oocytes at the germinal vesicle stage during in vitro maturation.
Journal: Biology of reproduction 20070901
Title: Aldosterone induces epithelial-mesenchymal transition via ROS of mitochondrial origin.
Journal: American journal of physiology. Renal physiology 20070901
Title: Up-regulation of early growth response gene 1 (EGR-1) via ERK1/2 signals attenuates sulindac sulfide-mediated cytotoxicity in the human intestinal epithelial cells.
Journal: Toxicology and applied pharmacology 20070901
Title: The central role of adenosine in statin-induced ERK1/2, Akt, and eNOS phosphorylation.
Journal: American journal of physiology. Heart and circulatory physiology 20070901
Title: Lithium regulates hippocampal neurogenesis by ERK pathway and facilitates recovery of spatial learning and memory in rats after transient global cerebral ischemia.
Journal: Neuropharmacology 20070901
Title: Sonic hedgehog promotes proliferation and differentiation of adult muscle cells: Involvement of MAPK/ERK and PI3K/Akt pathways.
Journal: Biochimica et biophysica acta 20070901
Title: RNA interference and inhibition of MEK-ERK signaling prevent abnormal skeletal phenotypes in a mouse model of craniosynostosis.
Journal: Nature genetics 20070901
Title: Ras pathway activation in malignant mesothelioma.
Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20070901
Title: 1alpha,25-Dihydroxyvitamin D(3) antiproliferative actions involve vitamin D receptor-mediated activation of MAPK pathways and AP-1/p21(waf1) upregulation in human osteosarcoma.
Journal: Cancer letters 20070828
Title: Role of ERK1/2 signaling pathways in 4-aminopyridine-induced rat pulmonary vasoconstriction.
Journal: European journal of pharmacology 20070813
Title: Predominant activation of MAP kinases and pro-destructive/pro-inflammatory features by TNF alpha in early-passage synovial fibroblasts via TNF receptor-1: failure of p38 inhibition to suppress matrix metalloproteinase-1 in rheumatoid arthritis.
Journal: Annals of the rheumatic diseases 20070801
Title: Folate deficiency in normal human fibroblasts leads to altered expression of genes primarily linked to cell signaling, the cytoskeleton and extracellular matrix.
Journal: The Journal of nutritional biochemistry 20070801
Title: Ras-MEK-ERK signaling cascade regulates androgen receptor element-inducible gene transcription and DNA synthesis in prostate cancer cells.
Journal: International journal of cancer 20070801
Title: An intrinsic ATPase activity of phospho-MEK-1 uncoupled from downstream ERK phosphorylation.
Journal: Archives of biochemistry and biophysics 20070801
Title: Follicle-stimulating hormone increases tuberin phosphorylation and mammalian target of rapamycin signaling through an extracellular signal-regulated kinase-dependent pathway in rat granulosa cells.
Journal: Endocrinology 20070801
Title: 6-Hydroxydopamine induces mitochondrial ERK activation.
Journal: Free radical biology & medicine 20070801
Title: Requirement for ERK MAP kinase in mouse preimplantation development.
Journal: Development (Cambridge, England) 20070801
Title: Extracellular signal-regulated kinase activation during renal ischemia/reperfusion mediates focal adhesion dissolution and renal injury.
Journal: The American journal of pathology 20070801
Title: Differential responses of human papillary thyroid cancer cell lines carrying the RET/PTC1 rearrangement or a BRAF mutation to MEK1/2 inhibitors.
Journal: Archives of otolaryngology--head & neck surgery 20070801
Title: PI3K/akt, JAK/STAT and MEK/ERK pathway inhibition protects retinal ganglion cells via different mechanisms after optic nerve injury.
Journal: The European journal of neuroscience 20070801
Title: Testosterone upregulation of tissue type plasminogen activator expression in Sertoli cells : tPA expression in Sertoli cells.
Journal: Endocrine 20070801
Title: Group V secretory PLA2 regulates TLR2-dependent eicosanoid generation in mouse mast cells through amplification of ERK and cPLA2alpha activation.
Journal: Blood 20070715
Title: Leukocyte antigen-related deficiency enhances insulin-like growth factor-1 signaling in vascular smooth muscle cells and promotes neointima formation in response to vascular injury.
Journal: The Journal of biological chemistry 20070706
Title: [The role of external signal regulated kinase and transforming growth factor beta(1) in asthma airway remodeling and regulation of glucocorticoids].
Journal: Zhonghua yi xue za zhi 20070703
Title: Activation of extracellular-signal-regulated kinase-1/2 precedes and is required for injury-induced Schwann cell proliferation.
Journal: Neuroreport 20070702
Title: Role of MAPK and PKA in regulation of rbOCT2-mediated renal organic cation transport.
Journal: American journal of physiology. Renal physiology 20070701
Title: Epiregulin promotes proliferation and migration of renal proximal tubular cells.
Journal: American journal of physiology. Renal physiology 20070701
Title: Phosphorylation of extracellular signal-regulated kinases in urinary bladder in rats with cyclophosphamide-induced cystitis.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20070701
Title: The acute phase protein alpha2-macroglobulin induces rat ventricular cardiomyocyte hypertrophy via ERK1,2 and PI3-kinase/Akt pathways.
Journal: Cardiovascular research 20070701
Title: Lutropin/choriogonadotropin stimulate the proliferation of primary cultures of rat Leydig cells through a pathway that involves activation of the extracellularly regulated kinase 1/2 cascade.
Journal: Endocrinology 20070701
Title: The onset of labor alters corticotropin-releasing hormone type 1 receptor variant expression in human myometrium: putative role of interleukin-1beta.
Journal: Endocrinology 20070701
Title: Inhibition of extracellular signal-regulated kinase (ERK1/2) activity reverses endotoxin-induced hypotension via decreased nitric oxide production in rats.
Journal: Pharmacological research 20070701
Title: Inhibition of the mitogen-activated protein kinase pathway results in the down-regulation of P-glycoprotein.
Journal: Molecular cancer therapeutics 20070701
Title: The MEK inhibitor, U0126, alters fertilization-induced [Ca2+]i oscillation parameters and secretion: differential effects associated with in vivo and in vitro meiotic maturation.
Journal: Developmental biology 20070615
Title: Selective inhibition of MEK1/2 reveals a differential requirement for ERK1/2 signalling in the regulation of HIF-1 in response to hypoxia and IGF-1.
Journal: Oncogene 20070607
Title: Induction of cyclooxygenase-2 expression by manganese in cultured astrocytes.
Journal: Neurochemistry international 20070601
Title: Carbon black particles increase reactive oxygen species formation in rat alveolar macrophages in vitro.
Journal: Archives of toxicology 20070601
Title: Hyperglycemia and hyperinsulinemia have additive effects on activation and proliferation of pancreatic stellate cells: possible explanation of islet-specific fibrosis in type 2 diabetes mellitus.
Journal: Journal of cellular biochemistry 20070601
Title: Asbestos-mediated CREB phosphorylation is regulated by protein kinase A and extracellular signal-regulated kinases 1/2.
Journal: American journal of physiology. Lung cellular and molecular physiology 20070601
Title: Indomethacin induces apoptosis in 786-O renal cell carcinoma cells by activating mitogen-activated protein kinases and AKT.
Journal: European journal of pharmacology 20070601
Title: Syk-dependent ERK activation regulates IL-2 and IL-10 production by DC stimulated with zymosan.
Journal: European journal of immunology 20070601
Title: Role for TGF-beta in cyclosporine-induced modulation of renal epithelial barrier function.
Journal: Journal of the American Society of Nephrology : JASN 20070601
Title: A form of perforant path LTP can occur without ERK1/2 phosphorylation or immediate early gene induction.
Journal: Learning & memory (Cold Spring Harbor, N.Y.) 20070601
Title: Effects of ACTH and expression of the melanocortin-2 receptor in the neonatal mouse testis.
Journal: Reproduction (Cambridge, England) 20070601
Title: Pyrophosphate inhibits mineralization of osteoblast cultures by binding to mineral, up-regulating osteopontin, and inhibiting alkaline phosphatase activity.
Journal: The Journal of biological chemistry 20070525
Title: The short chain fatty acid, butyrate, stimulates MUC2 mucin production in the human colon cancer cell line, LS174T.
Journal: Biochemical and biophysical research communications 20070511
Title: Role of mitogen-activated protein kinase (MAPK) in troglitazone-induced osteoblastic cell death.
Journal: Toxicology 20070505
Title: P38 and ERK mitogen-activated protein kinases mediate acrolein-induced apoptosis in Chinese hamster ovary cells.
Journal: Cellular signalling 20070501
Title: Vitamin A potentiates CpG-mediated memory B-cell proliferation and differentiation: involvement of early activation of p38MAPK.
Journal: Blood 20070501
Title: MEK1/2 inhibitors sensitize Bcr/Abl+ human leukemia cells to the dual Abl/Src inhibitor BMS-354/825.
Journal: Blood 20070501
Title: Hybrid lethality in interspecific F1 hybrid Nicotiana gossei x N. tabacum involves a MAP-kinases signalling cascade.
Journal: Plant biology (Stuttgart, Germany) 20070501
Title: Protein kinase C-ERK1/2 signal pathway switches glucose depletion-induced necrosis to apoptosis by regulating superoxide dismutases and suppressing reactive oxygen species production in A549 lung cancer cells.
Journal: Journal of cellular physiology 20070501
Title: Inhibition of ErbB2/neuregulin signaling augments paclitaxel-induced cardiotoxicity in adult ventricular myocytes.
Journal: Experimental cell research 20070501
Title: Advanced glycation endproducts mediate pro-inflammatory actions in human gestational tissues via nuclear factor-kappaB and extracellular signal-regulated kinase 1/2.
Journal: The Journal of endocrinology 20070501
Title: Hydroquinone, a reactive metabolite of benzene, reduces macrophage-mediated immune responses.
Journal: Molecules and cells 20070430
Title: Activation of MAPK in fibroblasts by Treponema denticola major outer sheath protein.
Journal: Biochemical and biophysical research communications 20070427
Title: Sphingosylphosphorylcholine induces apoptosis of endothelial cells through reactive oxygen species-mediated activation of ERK.
Journal: Journal of cellular biochemistry 20070415
Title: Differential regulation of indoleamine 2,3-dioxygenase by lipopolysaccharide and interferon gamma in murine bone marrow derived dendritic cells.
Journal: FEBS letters 20070403
Title: ERK1/2-driven and MKP-mediated inhibition of EGF-induced ERK5 signaling in human proximal tubular cells.
Journal: Journal of cellular physiology 20070401
Title: In vitro toxicity of tetrabromobisphenol-A on cerebellar granule cells: cell death, free radical formation, calcium influx and extracellular glutamate.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20070401
Title: Cytotoxicity of TBBPA and effects on proliferation, cell cycle and MAPK pathways in mammalian cells.
Journal: Chemosphere 20070401
Title: MEK-ERK is involved in SUMO-1 foci formation on apoptosis.
Journal: Cancer science 20070401
Title: Phosphorylation of p53 at serine 15 in A549 pulmonary epithelial cells exposed to vanadate: involvement of ATM pathway.
Journal: Toxicology and applied pharmacology 20070401
Title: Dual blockade of the Hedgehog and ERK1/2 pathways coordinately decreases proliferation and survival of cholangiocarcinoma cells.
Journal: Journal of cancer research and clinical oncology 20070401
Title: Phosphoinositide-3-kinase and mitogen activated protein kinase signaling pathways mediate acute NGF sensitization of TRPV1.
Journal: Molecular and cellular neurosciences 20070401
Title: Extracellular signal-regulated kinase (ERK) and nitric oxide synthase mediate intrathecal morphine-induced nociceptive behavior.
Journal: Neuropharmacology 20070401
Title: Inhibition of the MEK/ERK pathway reduces microglial activation and interleukin-1-beta expression in spinal cord ischemia/reperfusion injury in rats.
Journal: The Journal of thoracic and cardiovascular surgery 20070401
Title: The PI3K-Akt pathway promotes microtubule stabilization in migrating fibroblasts.
Journal: Genes to cells : devoted to molecular & cellular mechanisms 20070401
Title: Regulation of Leydig cell steroidogenesis by extracellular signal-regulated kinase 1/2: role of protein kinase A and protein kinase C signaling.
Journal: The Journal of endocrinology 20070401
Title: Dehydroepiandrosterone improves murine osteoblast growth and bone tissue morphometry via mitogen-activated protein kinase signaling pathway independent of either androgen receptor or estrogen receptor.
Journal: Journal of molecular endocrinology 20070401
Title: Signaling mechanisms leading to regulation of proliferation and differentiation of the mesenchymal chondrogenic cell line RCJ3.1C5.18 in response to IGF-I.
Journal: Journal of molecular endocrinology 20070401
Title: Participation of phosphatidyl inositol 3-kinase/protein kinase B and ERK1/2 pathways in interleukin-1beta stimulation of lactate production in Sertoli cells.
Journal: Reproduction (Cambridge, England) 20070401
Title: Nicotine-induced vascular endothelial growth factor release via the EGFR-ERK pathway in rat vascular smooth muscle cells.
Journal: Life sciences 20070320
Title: MAPK interacts with XGef and is required for CPEB activation during meiosis in Xenopus oocytes.
Journal: Journal of cell science 20070315
Title: Roles of the MEK1/2 and AKT pathways in CXCL12/CXCR4 induced cholangiocarcinoma cell invasion.
Journal: World journal of gastroenterology 20070314
Title: Erk1/2 MAPK and caldesmon differentially regulate podosome dynamics in A7r5 vascular smooth muscle cells.
Journal: Experimental cell research 20070310
Title: Functional role of beta-adrenergic receptors in the mitogenic action of nicotine on gastric cancer cells.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20070301
Title: Role of ROS and MAPK in TPA-induced ICAM-1 expression in the myeloid ML-1 cell line.
Journal: Journal of cellular biochemistry 20070301
Title: The antioxidant effect of estrogen and Selective Estrogen Receptor Modulators in the inhibition of osteocyte apoptosis in vitro.
Journal: Bone 20070301
Title: Apoptosis in early development of the sea urchin, Strongylocentrotus purpuratus.
Journal: Developmental biology 20070301
Title: MEK/ERK regulates adherens junctions and migration through Rac1.
Journal: Cell motility and the cytoskeleton 20070301
Title: Stimulation of catecholamine synthesis via activation of p44/42 MAPK in cultured bovine adrenal medullary cells by milnacipran.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20070301
Title: Vitamin C promotes human endothelial cell growth via the ERK-signaling pathway.
Journal: European journal of nutrition 20070301
Title: Insulin augments matrix metalloproteinase-9 expression in monocytes.
Journal: Cardiovascular research 20070301
Title: Iron causes interactions of TAK1, p21ras, and phosphatidylinositol 3-kinase in caveolae to activate IkappaB kinase in hepatic macrophages.
Journal: The Journal of biological chemistry 20070223
Title: Bone morphogenetic protein-4 abrogates lumen formation by mammary epithelial cells and promotes invasive growth.
Journal: Biochemical and biophysical research communications 20070216
Title: Propionate induces pH(i) changes through calcium flux, ERK1/2, p38, and PKC in bovine neutrophils.
Journal: Veterinary immunology and immunopathology 20070215
Title: Docetaxel-induced apoptosis of human melanoma is mediated by activation of c-Jun NH2-terminal kinase and inhibited by the mitogen-activated protein kinase extracellular signal-regulated kinase 1/2 pathway.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070215
Title: Absence of reciprocal feedback between MPF and ERK2 MAP kinase in mitotic Xenopus laevis embryo cell-free extract.
Journal: Cell cycle (Georgetown, Tex.) 20070215
Title: Ki67 expression levels are a better marker of reduced melanoma growth following MEK inhibitor treatment than phospho-ERK levels.
Journal: British journal of cancer 20070212
Title: Inhibitory effect of obovatol on nitric oxide production and activation of NF-kappaB/MAP kinases in lipopolysaccharide-treated RAW 264.7cells.
Journal: European journal of pharmacology 20070205
Title: A high nuclear basal level of ERK2 phosphorylation contributes to the resistance of cisplatin-resistant human ovarian cancer cells.
Journal: Gynecologic oncology 20070201
Title: 17beta-estradiol protects cortical neurons against oxidative stress-induced cell death through reduction in the activity of mitogen-activated protein kinase and in the accumulation of intracellular calcium.
Journal: Endocrinology 20070201
Title: Acetaminophen recruits spinal p42/p44 MAPKs and GH/IGF-1 receptors to produce analgesia via the serotonergic system.
Journal: Molecular pharmacology 20070201
Title: Neuroprotective effect of 17beta-estradiol against N-methyl-D-aspartate-induced retinal neurotoxicity via p-ERK induction.
Journal: Journal of neuroscience research 20070201
Title: A novel pathway for transcriptional regulation of alpha-synuclein.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070201
Title: The role of poly(ADP-ribose) polymerase (PARP) in the autonomous proliferative response of endothelial cells to hypoxia.
Journal: Cardiovascular research 20070201
Title: The role of chrysin and the ah receptor in induction of the human UGT1A1 gene in vitro and in transgenic UGT1 mice.
Journal: Hepatology (Baltimore, Md.) 20070201
Title: MEK1/2 regulates microtubule organization, spindle pole tethering and asymmetric division during mouse oocyte meiotic maturation.
Journal: Cell cycle (Georgetown, Tex.) 20070201
Title: Mechanisms of acquired androgen independence during arsenic-induced malignant transformation of human prostate epithelial cells.
Journal: Environmental health perspectives 20070201
Title: Intestinal D-galactose transport in an endotoxemia model in the rabbit.
Journal: The Journal of membrane biology 20070201
Title: [Effects of intrathecal injection of U0126 on the expression of phospho-CREB in spinal cord of morphine-induced withdrawal rats].
Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20070201
Title: Contributions of reactive oxygen species and mitogen-activated protein kinase signaling in arsenite-stimulated hemeoxygenase-1 production.
Journal: Toxicology and applied pharmacology 20070115
Title: Endothelin-1 induces hypertrophy and inhibits apoptosis in human airway smooth muscle cells.
Journal: American journal of physiology. Lung cellular and molecular physiology 20070101
Title: Heparan sulfate regulates the anabolic activity of MC3T3-E1 preosteoblast cells by induction of Runx2.
Journal: Journal of cellular physiology 20070101
Title: Prostaglandin E2 activates Stat3 in neonatal rat ventricular cardiomyocytes: A role in cardiac hypertrophy.
Journal: Cardiovascular research 20070101
Title: A proteomic analysis of the effect of MAPK pathway activation on L-glutamate-induced neuronal cell death.
Journal: Cellular & molecular biology letters 20070101
Title: JNK- and Rac1-dependent induction of immediate early gene pip92 suppresses neuronal differentiation.
Journal: Journal of neurochemistry 20070101
Title: Extracellular adenosine triphosphate induces glutamate transporter-1 expression in hippocampus.
Journal: Hippocampus 20070101
Title: Polyphenols downregulate PAI-1 gene expression in cultured human coronary artery endothelial cells: molecular contributor to cardiovascular protection.
Journal: Thrombosis research 20070101
Title: Induction of differentiation of colon cancer cells by combined inhibition of kinases and histone deacetylase.
Journal: Anticancer research 20070101
Title: Sphingosylphosphorylcholine stimulates expression of fibronectin through TGF-beta1-Smad-dependent mechanism in human mesenchymal stem cells.
Journal: The international journal of biochemistry & cell biology 20070101
Title: Regulation of hepatic oval cell proliferation by adenoviral mediated hepatocyte growth factor gene transfer and signal transduction inhibitors.
Journal: Hepato-gastroenterology 20070101
Title: Brain tumor formation in tuberous sclerosis depends on Erk activation.
Journal: Neuromolecular medicine 20070101
Title: C/EBPbeta associates with caspase 8 complex proteins and modulates apoptosis in hepatic stellate cells.
Journal: Journal of clinical gastroenterology 20070101
Title: Neural differentiation potentiated by the leukaemia inhibitory factor through STAT3 signalling in mouse embryonal carcinoma cells.
Journal: Folia biologica 20070101
Title: Ligand-dependent responses of the ErbB signaling network: experimental and modeling analyses.
Journal: Molecular systems biology 20070101
Title: gamma-Aminbuturic acid A receptor mitigates homocysteine-induced endothelial cell permeability.
Journal: Endothelium : journal of endothelial cell research 20070101
Title: Proteasome inhibition potentiates the cytotoxic effects of hyperthermia in HT-29 colon cancer cells through inhibition of heat shock protein 27.
Journal: Oncology 20070101
Title: Involvement of MAP kinases in lipopolysaccharide-induced histamine production in RAW 264 cells.
Journal: Life sciences 20061203
Title: Galpha13 mediates activation of the cytosolic phospholipase A2alpha through fine regulation of ERK phosphorylation.
Journal: Cellular signalling 20061201
Title: EGFR-mediated expression of aquaporin-3 is involved in human skin fibroblast migration.
Journal: The Biochemical journal 20061201
Title: Differing mechanisms of cAMP- versus seawater-induced oocyte maturation in marine nemertean worms II. The roles of tyrosine kinases and phosphatases.
Journal: Molecular reproduction and development 20061201
Title: 2,3,7,8-tetrachlorodibenzo-p-dioxin and epidermal growth factor cooperatively suppress peroxisome proliferator-activated receptor-gamma1 stimulation and restore focal adhesion complexes during adipogenesis: selective contributions of Src, Rho, and Erk distinguish these overlapping processes in C3H10T1/2 cells.
Journal: Molecular pharmacology 20061201
Title: Pharmacologic inhibitors of extracellular signal-regulated kinase (ERKs) and c-Jun NH(2)-terminal kinase (JNK) decrease glutathione content and sensitize human promonocytic leukemia cells to arsenic trioxide-induced apoptosis.
Journal: Journal of cellular physiology 20061201
Title: Evidence for the involvement of proline-directed serine/threonine phosphorylation in sperm capacitation.
Journal: Molecular human reproduction 20061201
Title: A novel BH3 mimetic reveals a mitogen-activated protein kinase-dependent mechanism of melanoma cell death controlled by p53 and reactive oxygen species.
Journal: Cancer research 20061201
Title: The HSP90 inhibitor 17-AAG synergizes with doxorubicin and U0126 in anaplastic large cell lymphoma irrespective of ALK expression.
Journal: Experimental hematology 20061201
Title: Inhibition of phosphatidylinositol-3-kinase and mitogen-activated protein kinase kinase 1/2 prevents melanoma development and promotes melanoma regression in the transgenic TPRas mouse model.
Journal: Molecular cancer therapeutics 20061201
Title: Sustained activation of extracellular signal-regulated kinase by nerve growth factor regulates c-fos protein stabilization and transactivation in PC12 cells.
Journal: Journal of neurochemistry 20061201
Title: [The role of MAPK/ERK1/2 signaling pathway in aldosterone stimulated transforming growth factor-beta1 synthesis in renal tubular epithelial cells].
Journal: Zhonghua yi xue za zhi 20061128
Title: Phosphorylation of extracellular signal-related protein kinase is required for rapid facilitation of heat-induced currents in rat dorsal root ganglion neurons.
Journal: Neuroscience 20061117
Title: Neuroprotective effect of N-acetylcysteine on neuronal apoptosis induced by a synthetic gingerdione compound: involvement of ERK and p38 phosphorylation.
Journal: Journal of neuroscience research 20061115
Title: Carnosol, a component of rosemary (Rosmarinus officinalis L.) protects nigral dopaminergic neuronal cells.
Journal: Neuroreport 20061106
Title: Butylated hydroxyanisole regulates ARE-mediated gene expression via Nrf2 coupled with ERK and JNK signaling pathway in HepG2 cells.
Journal: Molecular carcinogenesis 20061101
Title: Signal transduction of MEK/ERK and PI3K/Akt activation by hypoxia/reoxygenation in renal epithelial cells.
Journal: European journal of cell biology 20061101
Title: Neuroprotective role of ERK1/2 and ERK5 in a dopaminergic cell line under basal conditions and in response to oxidative stress.
Journal: Journal of neuroscience research 20061101
Title: Neurotrophic property of geniposide for inducing the neuronal differentiation of PC12 cells.
Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20061101
Title: Phytoestrogens regulate transcription and translation of vitamin D receptor in colon cancer cells.
Journal: The Journal of endocrinology 20061101
Title: Isolation and characterization of dominant and recessive IL-3-independent hematopoietic transformants.
Journal: Oncogene 20061026
Title: Mitogen-activated protein kinase signaling is essential for activity-dependent dendritic protein synthesis.
Journal: Neuroreport 20061023
Title: A novel method for detecting neutralizing antibodies against therapeutic proteins by measuring gene expression.
Journal: Journal of immunological methods 20061020
Title: PGE2 up-regulates EGF-like growth factor biosynthesis in human granulosa cells: new insights into the coordination between PGE2 and LH in ovulation.
Journal: Molecular human reproduction 20061001
Title: Signal transduction pathways involved in the stimulation of tissue type plasminogen activator by interleukin-1alpha and Porphyromonas gingivalis in human osteosarcoma cells.
Journal: Journal of periodontal research 20061001
Title: ERK contributes to the effects of Smad signaling on oxidized LDL-induced PAI-1 expression in human mesangial cells.
Journal: Translational research : the journal of laboratory and clinical medicine 20061001
Title: Impact of defined matrix interactions on insulin production by cultured human beta-cells: effect on insulin content, secretion, and gene transcription.
Journal: Diabetes 20061001
Title: Sustained versus transient ERK1/2 signaling underlies the anti- and proapoptotic effects of oxidative stress in human RPE cells.
Journal: Investigative ophthalmology & visual science 20061001
Title: Role of ERK 1/2 signaling in neuronal differentiation of cultured embryonic stem cells.
Journal: Development, growth & differentiation 20061001
Title: Acetaldehyde inhibits PPARgamma via H2O2-mediated c-Abl activation in human hepatic stellate cells.
Journal: Gastroenterology 20061001
Title: Meat hydrolysate and essential amino acid-induced glucagon-like peptide-1 secretion, in the human NCI-H716 enteroendocrine cell line, is regulated by extracellular signal-regulated kinase1/2 and p38 mitogen-activated protein kinases.
Journal: The Journal of endocrinology 20061001
Title: Role of megakaryoblastic acute leukemia-1 in ERK1/2-dependent stimulation of serum response factor-driven transcription by BDNF or increased synaptic activity.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060927
Title: The mitogen-activated/extracellular signal-regulated kinase kinase 1/2 inhibitor U0126 induces glial fibrillary acidic protein expression and reduces the proliferation and migration of C6 glioma cells.
Journal: Neuroscience 20060915
Title: Curcumin inhibits neurotensin-mediated interleukin-8 production and migration of HCT116 human colon cancer cells.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20060915
Title: Involvement of HDAC1 and the PI3K/PKC signaling pathways in NF-kappaB activation by the HDAC inhibitor apicidin.
Journal: Biochemical and biophysical research communications 20060908
Title: Up-regulation of cytosolic phospholipase A2alpha expression by N,N-diethyldithiocarbamate in PC12 cells; involvement of reactive oxygen species and nitric oxide.
Journal: Toxicology and applied pharmacology 20060901
Title: Inhibition of MEK/ERK1/2 signalling alters endothelial nitric oxide synthase activity in an agonist-dependent manner.
Journal: The Biochemical journal 20060901
Title: Angiotensin II-dependent Src and Smad1 signaling pathway is crucial for the development of diabetic nephropathy.
Journal: Laboratory investigation; a journal of technical methods and pathology 20060901
Title: Tissue-type plasminogen activator rescues neurones from serum deprivation-induced apoptosis through a mechanism independent of its proteolytic activity.
Journal: Journal of neurochemistry 20060901
Title: Inactivation of MAPK in mature oocytes triggers progression into mitosis via a Ca2+ -dependent pathway but without completion of S phase.
Journal: Journal of cell science 20060901
Title: Mitogen-activated protein kinase (MAPK) signalling pathways in HepG2 cells infected with a virulent strain of Klebsiella pneumoniae.
Journal: Cellular microbiology 20060901
Title: Gq/11-induced intracellular calcium mobilization mediates Per2 acute induction in Rat-1 fibroblasts.
Journal: Genes to cells : devoted to molecular & cellular mechanisms 20060901
Title: Constitutive phosphorylation of the S6 ribosomal protein via mTOR and ERK signaling in the peripheral blasts of acute leukemia patients.
Journal: Experimental hematology 20060901
Title: Role of MEK/ERK pathway in the MAD2-mediated cisplatin sensitivity in testicular germ cell tumour cells.
Journal: British journal of cancer 20060821
Title: Deregulated human glioma cell motility: inhibitory effect of somatostatin.
Journal: Molecular and cellular endocrinology 20060815
Title: Activation of Src/kinase/phospholipase C/mitogen-activated protein kinase and induction of neurite expression by ATP, independent of nerve growth factor.
Journal: Neuroscience 20060811
Title: Isoflurane preconditioning protects human neuroblastoma SH-SY5Y cells against in vitro simulated ischemia-reperfusion through the activation of extracellular signal-regulated kinases pathway.
Journal: European journal of pharmacology 20060807
Title: Insulin-like growth factor-I increases bone sialoprotein (BSP) expression through fibroblast growth factor-2 response element and homeodomain protein-binding site in the proximal promoter of the BSP gene.
Journal: Journal of cellular physiology 20060801
Title: Copper-induced stimulation of extracellular signal-regulated kinase in trout hepatocytes: the role of reactive oxygen species, Ca2+, and cell energetics and the impact of extracellular signal-regulated kinase signaling on apoptosis and necrosis.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20060801
Title: AUF-1 mediates inhibition by nitric oxide of lipopolysaccharide-induced matrix metalloproteinase-9 expression in cultured astrocytes.
Journal: Journal of neuroscience research 20060801
Title: cAMP regulates vasopressin-induced AQP2 expression via protein kinase A-independent pathway.
Journal: Biochimica et biophysica acta 20060801
Title: Activation of extracellular signal-regulated kinase (ERK) in G2 phase delays mitotic entry through p21CIP1.
Journal: Cell proliferation 20060801
Title: Tyrosine kinases: maiming myelin in leprosy.
Journal: Nature medicine 20060801
Title: ErbB2 receptor tyrosine kinase signaling mediates early demyelination induced by leprosy bacilli.
Journal: Nature medicine 20060801
Title: Regulation of lipopolysaccharide-induced interleukin-12 production by activation of repressor element GA-12 through hyperactivation of the ERK pathway.
Journal: Clinical and vaccine immunology : CVI 20060801
Title: [DHEA inhibits apoptosis of murine OB through MAPK signaling pathways independent of either ARs or ERs].
Journal: Fen zi xi bao sheng wu xue bao = Journal of molecular cell biology 20060801
Title: Involvement of Raf-1/MEK/ERK1/2 signaling pathway in zinc-induced injury in rat renal cortical slices.
Journal: The Journal of toxicological sciences 20060801
Title: Modulation and lack of cross-talk between signal transducer and activator of transcription 5 and Suppressor of cytokine signaling-3 in insulin and growth hormone signaling in 3T3-L1 adipocytes.
Journal: Obesity (Silver Spring, Md.) 20060801
Title: Perivascular adipose tissue promotes vasoconstriction: the role of superoxide anion.
Journal: Cardiovascular research 20060715
Title: p44/42 MAP kinase and c-Jun N-terminal kinase contribute to the up-regulation of caspase-3 in manganese-induced apoptosis in PC12 cells.
Journal: Brain research 20060712
Title: Enhanced ERK dependent CREB activation reduces apoptosis in staurosporine-treated human neuroblastoma SK-N-BE(2)C cells.
Journal: Neuroscience letters 20060710
Title: Hydrogen sulfide potentiates interleukin-1beta-induced nitric oxide production via enhancement of extracellular signal-regulated kinase activation in rat vascular smooth muscle cells.
Journal: Biochemical and biophysical research communications 20060707
Title: Green tea polyphenol stimulates cancer preventive effects of celecoxib in human lung cancer cells by upregulation of GADD153 gene.
Journal: International journal of cancer 20060701
Title: Fibroblast growth factor 2 and cyclic AMP synergistically regulate bone sialoprotein gene expression.
Journal: Bone 20060701
Title: Manganese modulates pro-inflammatory gene expression in activated glia.
Journal: Neurochemistry international 20060701
Title: Phosphorylation regulates Myc expression via prolonged activation of the mitogen-activated protein kinase pathway.
Journal: Journal of cellular physiology 20060701
Title: The role of ERK signaling and the P2X receptor on mechanical pain evoked by movement of inflamed knee joint.
Journal: Pain 20060701
Title: Endothelin-1 activates Homer 1alpha expression via mitogen-activated protein kinase in cardiac myocytes.
Journal: International journal of molecular medicine 20060701
Title: Oxidized-HDL3 modulates the expression of Cox-2 in human endothelial cells.
Journal: International journal of molecular medicine 20060701
Title: AMP-activated protein kinase activation modulates progesterone secretion in granulosa cells from hen preovulatory follicles.
Journal: The Journal of endocrinology 20060701
Title: Lysophosphatidic acid cooperates with 1alpha,25(OH)2D3 in stimulating human MG63 osteoblast maturation.
Journal: Prostaglandins & other lipid mediators 20060701
Title: Contrasting actions of prolonged mitogen-activated protein kinase activation on cell survival.
Journal: Biochemical and biophysical research communications 20060630
Title: Protein kinase C zeta mediates epidermal growth factor-induced growth of head and neck tumor cells by regulating mitogen-activated protein kinase.
Journal: Cancer research 20060615
Title: Estrogen has a neuroprotective effect on axotomized RGCs through ERK signal transduction pathway.
Journal: Brain research 20060606
Title: Sphingosine-1-phosphate induces COX-2 expression via PI3K/Akt and p42/p44 MAPK pathways in rat vascular smooth muscle cells.
Journal: Journal of cellular physiology 20060601
Title: Substance P release evoked by capsaicin or potassium from rat cultured dorsal root ganglion neurons is conversely modulated with bradykinin.
Journal: Journal of neurochemistry 20060601
Title: Importance of the stress kinase p38alpha in mediating the direct cytotoxic effects of the thalidomide analogue, CPS49, in cancer cells and endothelial cells.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20060601
Title: Mast cell chymase induces expression of chemokines for neutrophils in eosinophilic EoL-1 cells and mouse peritonitis eosinophils.
Journal: European journal of pharmacology 20060524
Title: HDAC inhibition is associated to valproic acid induction of early megakaryocytic markers.
Journal: Experimental cell research 20060515
Title: Inhibition of the ERK/MAP kinase pathway attenuates heme oxygenase-1 expression and heme-mediated neuronal injury.
Journal: Neuroscience letters 20060508
Title: Loose ligation of the sciatic nerve in rats elicits transient up-regulation of Homer1a gene expression in the spinal dorsal horn.
Journal: Neuroscience letters 20060508
Title: Superoxide anions and hydrogen peroxide induce hepatocyte death by different mechanisms: involvement of JNK and ERK MAP kinases.
Journal: Journal of hepatology 20060501
Title: Disruption of gap junctional communication within the ovarian follicle induces oocyte maturation.
Journal: Endocrinology 20060501
Title: Pregnancy-enhanced endothelial nitric oxide synthase (eNOS) activation in uterine artery endothelial cells shows altered sensitivity to Ca2+, U0126, and wortmannin but not LY294002--evidence that pregnancy adaptation of eNOS activation occurs at multiple levels of cell signaling.
Journal: Endocrinology 20060501
Title: Intracellular Ca2+ increase induces post-fertilization events via MAP kinase dephosphorylation in eggs of the hydrozoan jellyfish Cladonema pacificum.
Journal: Developmental biology 20060501
Title: Transcriptional up-regulation of MMP12 and MMP13 by asbestos occurs via a PKCdelta-dependent pathway in murine lung.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060501
Title: Notoginsenoside R1 inhibits TNF-alpha-induced fibronectin production in smooth muscle cells via the ROS/ERK pathway.
Journal: Free radical biology & medicine 20060501
Title: Multiple signaling pathways must be targeted to overcome drug resistance in cell lines derived from melanoma metastases.
Journal: Molecular cancer therapeutics 20060501
Title: Nerve growth factor activates brain-derived neurotrophic factor promoter IV via extracellular signal-regulated protein kinase 1/2 in PC12 cells.
Journal: Molecules and cells 20060430
Title: Effect of chlorpromazine on bone sialoprotein (BSP) gene transcription.
Journal: Journal of cellular biochemistry 20060415
Title: Prolonged activation of cAMP-response element-binding protein and ATF-2 needed for nicotine-triggered elevation of tyrosine hydroxylase gene transcription in PC12 cells.
Journal: The Journal of biological chemistry 20060414
Title: IGF-1 induced vascular endothelial growth factor secretion in head and neck squamous cell carcinoma.
Journal: Biochemical and biophysical research communications 20060414
Title: Transcriptional regulation of VCAM-1 expression by tumor necrosis factor-alpha in human tracheal smooth muscle cells: involvement of MAPKs, NF-kappaB, p300, and histone acetylation.
Journal: Journal of cellular physiology 20060401
Title: Notoginsenoside R1 from Panax notoginseng inhibits TNF-alpha-induced PAI-1 production in human aortic smooth muscle cells.
Journal: Vascular pharmacology 20060401
Title: The effects of ZD1839 (Iressa), a highly selective EGFR tyrosine kinase inhibitor, as a radiosensitiser in bile duct carcinoma cell lines.
Journal: International journal of oncology 20060401
Title: Leptin receptor expression and cell signaling in breast cancer.
Journal: International journal of oncology 20060401
Title: PTEN sensitizes epidermal growth factor-mediated proliferation in endometrial carcinoma cells.
Journal: Oncology reports 20060401
Title: Lead increases lipopolysaccharide-induced liver-injury through tumor necrosis factor-alpha overexpression by monocytes/macrophages: role of protein kinase C and P42/44 mitogen-activated protein kinase.
Journal: Environmental health perspectives 20060401
Title: Induction of steroidogenesis in immature rat Leydig cells by interleukin-1alpha is dependent on extracellular signal-regulated kinases.
Journal: Journal of molecular endocrinology 20060401
Title: Integrin alpha2-mediated ERK and calpain activation play a critical role in cell adhesion and motility via focal adhesion kinase signaling: identification of a novel signaling pathway.
Journal: The Journal of biological chemistry 20060331
Title: Phosphorylation of the hinge domain of the nuclear hormone receptor LRH-1 stimulates transactivation.
Journal: The Journal of biological chemistry 20060324
Title: Rapid degradation of Bim by the ubiquitin-proteasome pathway mediates short-term ischemic tolerance in cultured neurons.
Journal: The Journal of biological chemistry 20060317
Title: Activation of ERK1/2 and p38 kinases by polycyclic aromatic hydrocarbons in rat liver epithelial cells is associated with induction of apoptosis.
Journal: Toxicology and applied pharmacology 20060315
Title: Regulation of cardiotrophin-1 expression in mouse embryonic stem cells by HIF-1alpha and intracellular reactive oxygen species.
Journal: Journal of cell science 20060315
Title: Reactive oxygen species modulate independent protein phosphorylation pathways during human sperm capacitation.
Journal: Free radical biology & medicine 20060315
Title: Signalling responses linked to betulinic acid-induced apoptosis are antagonized by MEK inhibitor U0126 in adherent or 3D spheroid melanoma irrespective of p53 status.
Journal: International journal of cancer 20060301
Title: Regulation of homocysteine-induced MMP-9 by ERK1/2 pathway.
Journal: American journal of physiology. Cell physiology 20060301
Title: Activity-dependent potentiation of large dense-core vesicle release modulated by mitogen-activated protein kinase/extracellularly regulated kinase signaling.
Journal: Endocrinology 20060301
Title: Dedifferentiation of adult monkey Sertoli cells through activation of extracellularly regulated kinase 1/2 induced by heat treatment.
Journal: Endocrinology 20060301
Title: Phosphorylation sites on calcium channel alpha1 and beta subunits regulate ERK-dependent modulation of neuronal N-type calcium channels.
Journal: Cell calcium 20060301
Title: Flagellin of Pseudomonas aeruginosa inhibits Na+ transport in airway epithelia.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060301
Title: S-glutathiolation by peroxynitrite of p21ras at cysteine-118 mediates its direct activation and downstream signaling in endothelial cells.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060301
Title: P2Y12 receptor-mediated potentiation of thrombin-induced thromboxane A2 generation in platelets occurs through regulation of Erk1/2 activation.
Journal: Journal of thrombosis and haemostasis : JTH 20060301
Title: Insulin-like growth factor-I promotes migration in human androgen-independent prostate cancer cells via the alphavbeta3 integrin and PI3-K/Akt signaling.
Journal: International journal of oncology 20060301
Title: Calcium signaling stimulates translation of HIF-alpha during hypoxia.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060301
Title: Combined inhibition of the phosphatidylinositol 3-kinase/Akt and Ras/mitogen-activated protein kinase pathways results in synergistic effects in glioblastoma cells.
Journal: Molecular cancer therapeutics 20060301
Title: Sulindac independently modulates extracellular signal-regulated kinase 1/2 and cyclic GMP-dependent protein kinase signaling pathways.
Journal: Molecular cancer therapeutics 20060301
Title: Mitogen-activated protein kinases control cardiac KChIP2 gene expression.
Journal: Circulation research 20060217
Title: Involvement of phosphatidylinositol 3-kinase and extracellular-regulated kinase in hepatic stellate cell antioxidant response and myofibroblastic transdifferentiation.
Journal: Archives of biochemistry and biophysics 20060215
Title: Role for mitogen-activated protein kinases in phenobarbital-induced expression of cytochrome P450 2B in primary cultures of rat hepatocytes.
Journal: Toxicology letters 20060208
Title: Retinoid-mediated stimulation of steroid sulfatase activity in myeloid leukemic cell lines requires RARalpha and RXR and involves the phosphoinositide 3-kinase and ERK-MAP kinase pathways.
Journal: Journal of cellular biochemistry 20060201
Title: Human airway trypsin-like protease stimulates human bronchial fibroblast proliferation in a protease-activated receptor-2-dependent pathway.
Journal: American journal of physiology. Lung cellular and molecular physiology 20060201
Title: Nonclassical action of retinoic acid on the activation of the cAMP response element-binding protein in normal human bronchial epithelial cells.
Journal: Molecular biology of the cell 20060201
Title: Involvement of COX-2 in VEGF-induced angiogenesis via P38 and JNK pathways in vascular endothelial cells.
Journal: Cardiovascular research 20060201
Title: Porphyromonas gingivalis-related cardiac cell apoptosis was majorly co-activated by p38 and extracellular signal-regulated kinase pathways.
Journal: Journal of periodontal research 20060201
Title: Characterization of anti-apoptotic action of TCDD as a defensive cellular stress response reaction against the cell damaging action of ultra-violet irradiation in an immortalized normal human mammary epithelial cell line, MCF10A.
Journal: Toxicology 20060116
Title: Posttranscriptional regulation of TNFalpha expression via eukaryotic initiation factor 4E (eIF4E) phosphorylation in mouse macrophages.
Journal: Cytokine 20060107
Title: MEK hyperphosphorylation coincides with cell cycle shut down of cultured smooth muscle cells.
Journal: Journal of cellular physiology 20060101
Title: Characterization of compound mechanisms and secondary activities by BioMAP analysis.
Journal: Journal of pharmacological and toxicological methods 20060101
Title: Cyclooxygenase-2 induction by bradykinin in aortic vascular smooth muscle cells.
Journal: American journal of physiology. Heart and circulatory physiology 20060101
Title: Endogenous adenosine protects preconditioned heart during early minutes of reperfusion by activating Akt.
Journal: American journal of physiology. Heart and circulatory physiology 20060101
Title: Deltamethrin, a pyrethroid insecticide, is a potent inducer for the activity-dependent gene expression of brain-derived neurotrophic factor in neurons.
Journal: The Journal of pharmacology and experimental therapeutics 20060101
Title: Glutamate excitotoxicity is involved in cell death caused by tributyltin in cultured rat cortical neurons.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20060101
Title: The mitogen-activated protein kinase/extracellular signal-regulated kinase kinase inhibitor PD184352 (CI-1040) selectively induces apoptosis in malignant schwannoma cell lines.
Journal: The Journal of pharmacology and experimental therapeutics 20060101
Title: A role of p44/42 mitogen-activated protein kinases in formyl-peptide receptor-mediated phospholipase D activity and oxidant production.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060101
Title: Fibroblast growth factor 2 applied to the optic nerve after axotomy up-regulates BDNF and TrkB in ganglion cells by activating the ERK and PKA signaling pathways.
Journal: Journal of neurochemistry 20060101
Title: Inhibition of mitogen-activated protein kinase signalling by Bacillus anthracis lethal toxin causes destabilization of interleukin-8 mRNA.
Journal: Cellular microbiology 20060101
Title: Differential regulation of interleukin-12 and tumour necrosis factor-alpha by phosphatidylinositol 3-kinase and ERK 1/2 pathways during Mycobacterium tuberculosis infection.
Journal: Clinical and experimental immunology 20060101
Title: Impaired inflammatory pain and thermal hyperalgesia in mice expressing neuron-specific dominant negative mitogen activated protein kinase kinase (MEK).
Journal: Molecular pain 20060101
Title: Trimidox induces apoptosis via cytochrome c release in NALM-6 human B cell leukaemia cells.
Journal: Basic & clinical pharmacology & toxicology 20060101
Title: Extracellular signal-regulated mitogen-activated protein kinase inhibitors decrease amphetamine-induced behavior and neuropeptide gene expression in the striatum.
Journal: Neuroscience 20060101
Title: The effects of a novel MEK inhibitor PD184161 on MEK-ERK signaling and growth in human liver cancer.
Journal: Neoplasia (New York, N.Y.) 20060101
Title: Suppression of pro-metastasis phenotypes expression in malignant pleural mesothelioma by the PI3K inhibitor LY294002 or the MEK inhibitor UO126.
Journal: Anticancer research 20060101
Title: Induction of interleukin-8 secretion and activation of ERK1/2, p38 MAPK signaling pathways by thrombin in dermal fibroblasts.
Journal: The international journal of biochemistry & cell biology 20060101
Title: Genetic and pharmacologic dissection of Ras effector utilization in oncogenesis.
Journal: Methods in enzymology 20060101
Title: Erk is involved in the differentiation induced by diallyl disulfide in the human gastric cancer cell line MGC803.
Journal: Cellular & molecular biology letters 20060101
Title: Down-regulation of c-Myc following MEK/ERK inhibition halts the expression of malignant phenotype in rhabdomyosarcoma and in non muscle-derived human tumors.
Journal: Molecular cancer 20060101
Title: Acrylonitrile-induced extracellular signal-regulated kinase (ERK) activation via protein kinase C (PKC) in SK-N-SH neuroblastoma cells.
Journal: Journal of applied toxicology : JAT 20060101
Title: 5-Hydroxytryptamine as a potent migration enhancer of human aortic endothelial cells.
Journal: FEBS letters 20051219
Title: Induction of cyclooxygenase-2 by benzo[a]pyrene diol epoxide through inhibition of retinoic acid receptor-beta 2 expression.
Journal: Oncogene 20051215
Title: Nerve growth factor increases connexin43 phosphorylation and gap junctional intercellular communication.
Journal: Journal of neuroscience research 20051215
Title: Hypothermia and ERK activation after cardiac arrest.
Journal: Brain research 20051207
Title: Upregulation of neuropilin-1 by basic fibroblast growth factor enhances vascular smooth muscle cell migration in response to VEGF.
Journal: Cytokine 20051207
Title: Activation of the spinal ERK signaling pathway contributes naloxone-precipitated withdrawal in morphine-dependent rats.
Journal: Pain 20051205
Title: A novel role for glucocorticoid-induced leucine zipper protein in epithelial sodium channel-mediated sodium transport.
Journal: The Journal of biological chemistry 20051202
Title: Ciglitazone-induced p27 gene transcriptional activity is mediated through Sp1 and is negatively regulated by the MAPK signaling pathway.
Journal: Cellular signalling 20051201
Title: Endothelin-1 and isoprenaline co-stimulation causes contractile failure which is partially reversed by MEK inhibition.
Journal: Cardiovascular research 20051201
Title: Involvement of histone acetyltransferase (HAT) in ethanol-induced acetylation of histone H3 in hepatocytes: potential mechanism for gene expression.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20051201
Title: Ontogeny of rapid estrogen-mediated extracellular signal-regulated kinase signaling in the rat cerebellar cortex: potent nongenomic agonist and endocrine disrupting activity of the xenoestrogen bisphenol A.
Journal: Endocrinology 20051201
Title: Genistein-induced neuronal differentiation is associated with activation of extracellular signal-regulated kinases and upregulation of p21 and N-cadherin.
Journal: Journal of cellular biochemistry 20051201
Title: The hyaluronan-binding protease upregulates ERK1/2 and PI3K/Akt signalling pathways in fibroblasts and stimulates cell proliferation and migration.
Journal: Cellular signalling 20051201
Title: Suppression of p65 phosphorylation coincides with inhibition of IkappaBalpha polyubiquitination and degradation.
Journal: Molecular carcinogenesis 20051201
Title: Cocaine-induced CREB phosphorylation in nucleus accumbens of cocaine-sensitized rats is enabled by enhanced activation of extracellular signal-related kinase, but not protein kinase A.
Journal: Journal of neurochemistry 20051201
Title: Inhibition of angiotensin II- and endothelin-1-stimulated proliferation by selective MEK inhibitor in cultured rabbit gingival fibroblastsdagger.
Journal: Fundamental & clinical pharmacology 20051201
Title: Interaction between Polyamines and the Mitogen-Activated Protein Kinase Pathway in the Regulation of Cell Cycle Variables in Breast Cancer Cells.
Journal: Cancer research 20051201
Title: Examination of the signal transduction pathways leading to upregulation of tissue type plasminogen activator by Porphyromonas endodontalis in human pulp cells.
Journal: International endodontic journal 20051201
Title: Inhibition of mitogen-activated protein kinase kinase enhances apoptosis induced by arsenic trioxide in human breast cancer MCF-7 cells.
Journal: Clinical and experimental pharmacology & physiology 20051201
Title: Conjugated linoleic acid promotes human adipocyte insulin resistance through NFkappaB-dependent cytokine production.
Journal: The Journal of biological chemistry 20051118
Title: Activation of p-ERK1/2 by nicotine in pancreatic tumor cell line AR42J: effects on proliferation and secretion.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20051101
Title: M-CSF stimulated differentiation requires persistent MEK activity and MAPK phosphorylation independent of Grb2-Sos association and phosphatidylinositol 3-kinase activity.
Journal: Cellular signalling 20051101
Title: Progesterone pre-treatment potentiates EGF pathway signaling in the breast cancer cell line ZR-75.
Journal: Breast cancer research and treatment 20051101
Title: Targeted inhibition of transient activation of the EGFR-mediated cell survival pathway enhances paclitaxel-induced ovarian cancer cell death.
Journal: International journal of oncology 20051101
Title: Experimental treatment for focal hyperglycemic ischemic brain injury in the rat.
Journal: Experimental brain research 20051101
Title: Globular adiponectin decreases leptin-induced tumor necrosis factor-alpha expression by murine macrophages: involvement of cAMP-PKA and MAPK pathways.
Journal: Cellular immunology 20051101
Title: Role of hippocampal Cav1.2 Ca2+ channels in NMDA receptor-independent synaptic plasticity and spatial memory.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20051026
Title: Activation of C-Jun N-terminal kinase is required for glutathione transferase A4 induction during oxidative stress, not during cell proliferation, in mouse hepatocytes.
Journal: FEBS letters 20051024
Title: Apoptosis induced by the kinase inhibitor BAY 43-9006 in human leukemia cells involves down-regulation of Mcl-1 through inhibition of translation.
Journal: The Journal of biological chemistry 20051021
Title: Silibinin inhibits cell invasion through inactivation of both PI3K-Akt and MAPK signaling pathways.
Journal: Chemico-biological interactions 20051020
Title: ERK1/2 inhibition increases antiestrogen treatment efficacy by interfering with hypoxia-induced downregulation of ERalpha: a combination therapy potentially targeting hypoxic and dormant tumor cells.
Journal: Oncogene 20051013
Title: Inhibition of iNOS gene expression by quercetin is mediated by the inhibition of IkappaB kinase, nuclear factor-kappa B and STAT1, and depends on heme oxygenase-1 induction in mouse BV-2 microglia.
Journal: European journal of pharmacology 20051003
Title: 4-Hydroxyestradiol induces oxidative stress and apoptosis in human mammary epithelial cells: possible protection by NF-kappaB and ERK/MAPK.
Journal: Toxicology and applied pharmacology 20051001
Title: HIV-1 gp120-induced TNF-{alpha} production by primary human macrophages is mediated by phosphatidylinositol-3 (PI-3) kinase and mitogen-activated protein (MAP) kinase pathways.
Journal: Journal of leukocyte biology 20051001
Title: Expression of proline-rich Akt-substrate PRAS40 in cell survival pathway and carcinogenesis.
Journal: Acta pharmacologica Sinica 20051001
Title: Activation of protein kinase CbetaI constitutes a new neurotrophic pathway for deafferented spiral ganglion neurons.
Journal: Journal of cell science 20051001
Title: Nerve growth factor-induced expression of the GTP cyclohydrolase I gene via Ras/MEK pathway in PC12D cells.
Journal: Journal of neurochemistry 20051001
Title: Inhibitory effect of 14-3-3 proteins on serum-induced proliferation of cardiac fibroblasts.
Journal: European journal of cell biology 20051001
Title: Anisomycin induces COX-2 mRNA expression through p38(MAPK) and CREB independent of small GTPases in intestinal epithelial cells.
Journal: Biochimica et biophysica acta 20050930
Title: LTB4 stimulates growth of human pancreatic cancer cells via MAPK and PI-3 kinase pathways.
Journal: Biochemical and biophysical research communications 20050930
Title: Molecular substrates for retrieval and reconsolidation of cocaine-associated contextual memory.
Journal: Neuron 20050915
Title: Erk pathway inhibitor U0126 induces gamma-globin expression in erythroid cells.
Journal: Cellular and molecular biology (Noisy-le-Grand, France) 20050905
Title: Contributions of the mitogen-activated protein kinase and protein kinase C cascades in spatial learning and memory mediated by the nucleus accumbens.
Journal: The Journal of pharmacology and experimental therapeutics 20050901
Title: Vitamin K3 (menadione)-induced oncosis associated with keratin 8 phosphorylation and histone H3 arylation.
Journal: Molecular pharmacology 20050901
Title: Calcium-activated RAF/MEK/ERK signaling pathway mediates p53-dependent apoptosis and is abrogated by alpha B-crystallin through inhibition of RAS activation.
Journal: Molecular biology of the cell 20050901
Title: Synergistic interactions between MEK1/2 and histone deacetylase inhibitors in BCR/ABL+ human leukemia cells.
Journal: Leukemia 20050901
Title: Activation of ERK mitogen-activated protein kinase in human cells by the mycotoxin patulin.
Journal: Toxicology and applied pharmacology 20050901
Title: Inhibition of either phosphatidylinositol 3-kinase/Akt or the mitogen/extracellular-regulated kinase, MEK/ERK, signaling pathways suppress growth of breast cancer cell lines, but MEK/ERK signaling is critical for cell survival.
Journal: Breast cancer research and treatment 20050901
Title: Functional interactions of Raf and MEK with Jun-N-terminal kinase (JNK) result in a positive feedback loop on the oncogenic Ras signaling pathway.
Journal: Biochemistry 20050816
Title: Heparin-binding epidermal growth factor-like growth factor stimulates cell proliferation in cerebral cortical cultures through phosphatidylinositol 3'-kinase and mitogen-activated protein kinase.
Journal: Journal of neuroscience research 20050815
Title: Identification and bioactivities of IFN-gamma in rainbow trout Oncorhynchus mykiss: the first Th1-type cytokine characterized functionally in fish.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20050815
Title: The FLT3 internal tandem duplication mutation prevents apoptosis in interleukin-3-deprived BaF3 cells due to protein kinase A and ribosomal S6 kinase 1-mediated BAD phosphorylation at serine 112.
Journal: Cancer research 20050815
Title: PKB/AKT and ERK regulation of caspase-mediated apoptosis by methylseleninic acid in LNCaP prostate cancer cells.
Journal: Carcinogenesis 20050801
Title: Effects of organochlorine insecticides on MAP kinase pathways in human HaCaT keratinocytes: key role of reactive oxygen species.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20050801
Title: Cocaine- and amphetamine-regulated transcript (CART) peptide activates the extracellular signal-regulated kinase (ERK) pathway in AtT20 cells via putative G-protein coupled receptors.
Journal: Neuroscience letters 20050801
Title: Gas6 induces Akt/mTOR-mediated mesangial hypertrophy in diabetic nephropathy.
Journal: Kidney international 20050801
Title: Calmodulin-dependent protein kinases phosphorylate gp130 at the serine-based dileucine internalization motif.
Journal: Biochimica et biophysica acta 20050801
Title: Modulation of tumor necrosis factor-alpha and oxidative stress through protein kinase C and P42/44 mitogen-activated protein kinase in lead increases lipopolysaccharide-induced liver damage in rats.
Journal: Shock (Augusta, Ga.) 20050801
Title: 17beta-estradiol stimulates MAPK signaling pathway in human lens epithelial cell cultures preventing collapse of mitochondrial membrane potential during acute oxidative stress.
Journal: Mitochondrion 20050801
Title: The MAP kinase pathway mediates transcytosis induced by TNF-alpha in an in vitro blood-brain barrier model.
Journal: The European journal of neuroscience 20050801
Title: Inhibition of platelet-derived growth factor-induced cell growth signaling by a short interfering RNA for EWS-Fli1 via down-regulation of phospholipase D2 in Ewing sarcoma cells.
Journal: The Journal of biological chemistry 20050729
Title: Macrophages survive hyperoxia via prolonged ERK activation due to phosphatase down-regulation.
Journal: The Journal of biological chemistry 20050715
Title: Differential roles of p39Mos-Xp42Mpk1 cascade proteins on Raf1 phosphorylation and spindle morphogenesis in Xenopus oocytes.
Journal: Developmental biology 20050715
Title: Eosinophil migration induced by mast cell chymase is mediated by extracellular signal-regulated kinase pathway.
Journal: Biochemical and biophysical research communications 20050715
Title: Radical mediators and mitogen-activated protein kinase signaling in oxygen-dependent radiosensitivity of human tumor cell lines.
Journal: Free radical biology & medicine 20050715
Title: Netrin-1 induces axon branching in developing cortical neurons by frequency-dependent calcium signaling pathways.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050713
Title: MAP kinases in lung endothelial permeability induced by microtubule disassembly.
Journal: American journal of physiology. Lung cellular and molecular physiology 20050701
Title: Analysis of 5-HT-induced short-term facilitation at Aplysia sensorimotor synapse during bursts: increased synaptic gain that does not require ERK activation.
Journal: Journal of neurophysiology 20050701
Title: Luteinizing hormone-induced extracellular-signal regulated kinase activation differently modulates progesterone and androstenedione production in bovine theca cells.
Journal: Endocrinology 20050701
Title: Investigating the neuroprotective mechanism of action of a CDK5 inhibitor by phosphoproteome analysis.
Journal: Journal of cellular biochemistry 20050701
Title: Inhibiting MAP kinase activity prevents calcium transients and mitosis entry in early sea urchin embryos.
Journal: The Journal of biological chemistry 20050701
Title: Thymidine phosphorylase suppresses apoptosis induced by microtubule-interfering agents.
Journal: Biochemical pharmacology 20050701
Title: PKC-induced ERK1/2 interactions and downstream effectors in ovine cerebral arteries.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20050701
Title: MAPK and PI3K inhibition reduces proliferation of Barrett's adenocarcinoma in vitro.
Journal: The Journal of surgical research 20050701
Title: Ras-mediated loss of the pro-apoptotic response protein Par-4 is mediated by DNA hypermethylation through Raf-independent and Raf-dependent signaling cascades in epithelial cells.
Journal: The Journal of biological chemistry 20050617
Title: Resveratrol upregulates heme oxygenase-1 expression via activation of NF-E2-related factor 2 in PC12 cells.
Journal: Biochemical and biophysical research communications 20050617
Title: Activation of protein synthesis in cardiomyocytes by the hypertrophic agent phenylephrine requires the activation of ERK and involves phosphorylation of tuberous sclerosis complex 2 (TSC2).
Journal: The Biochemical journal 20050615
Title: Beta-amyloid-induced apoptosis is associated with cyclooxygenase-2 up-regulation via the mitogen-activated protein kinase-NF-kappaB signaling pathway.
Journal: Free radical biology & medicine 20050615
Title: Auditory fear conditioning and long-term potentiation in the lateral amygdala require ERK/MAP kinase signaling in the auditory thalamus: a role for presynaptic plasticity in the fear system.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050615
Title: Mechanism of feedback regulation of insulin receptor substrate-1 phosphorylation in primary adipocytes.
Journal: The Biochemical journal 20050601
Title: Artocarpol A stimulation of superoxide anion generation in neutrophils involved the activation of PLC, PKC and p38 mitogen-activated PK signaling pathways.
Journal: British journal of pharmacology 20050601
Title: Magnolol induces the distributional changes of p160 and adipose differentiation-related protein in adrenal cells.
Journal: Histochemistry and cell biology 20050601
Title: Complementary antagonistic actions between C-type natriuretic peptide and the MAPK pathway through FGFR-3 in ATDC5 cells.
Journal: Bone 20050601
Title: Activation of spinal extracellular signaling-regulated kinases by intraplantar melittin injection.
Journal: Neuroscience letters 20050601
Title: PTHrP signaling targets cyclin D1 and induces osteoblastic cell growth arrest.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20050601
Title: Pharmacologic inhibition of RAF-->MEK-->ERK signaling elicits pancreatic cancer cell cycle arrest through induced expression of p27Kip1.
Journal: Cancer research 20050601
Title: Light stimulates MSK1 activation in the suprachiasmatic nucleus via a PACAP-ERK/MAP kinase-dependent mechanism.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050601
Title: 7-Ketocholesterol-induced apoptosis. Involvement of several pro-apoptotic but also anti-apoptotic calcium-dependent transduction pathways.
Journal: The FEBS journal 20050601
Title: Angiotensin II promotes leptin production in cultured human fat cells by an ERK1/2-dependent pathway.
Journal: Obesity research 20050601
Title: The effect of epidermal growth factor on production of vascular endothelial growth factor by amnion-derived (WISH) cells.
Journal: Growth factors (Chur, Switzerland) 20050601
Title: MAPK pathway contributes to density- and hypoxia-induced expression of the tumor-associated carbonic anhydrase IX.
Journal: Biochimica et biophysica acta 20050525
Title: PKCalpha is involved in phorbol ester TPA-mediated stabilization of p14ARF.
Journal: Biochemical and biophysical research communications 20050520
Title: Transcriptional profiling of gamma delta T cells identifies a role for vitamin D in the immunoregulation of the V gamma 9V delta 2 response to phosphate-containing ligands.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20050515
Title: P2Y2 nucleotide receptors enhance alpha-secretase-dependent amyloid precursor protein processing.
Journal: The Journal of biological chemistry 20050513
Title: Benzoquinone activates the ERK/MAPK signaling pathway via ROS production in HL-60 cells.
Journal: Toxicology 20050505
Title: Nitric oxide decreases surfactant protein gene expression in primary cultures of type II pneumocytes.
Journal: American journal of physiology. Lung cellular and molecular physiology 20050501
Title: In vivo adenosine receptor preconditioning reduces myocardial infarct size via subcellular ERK signaling.
Journal: American journal of physiology. Heart and circulatory physiology 20050501
Title: Decrease in cytosolic phospholipase A2alpha mRNA levels by reactive oxygen species via MAP kinase pathways in PC12 cells: effects of dopaminergic neurotoxins.
Journal: Cellular signalling 20050501
Title: Juzentaihoto, a Kampo medicine, enhances IL-12 production by modulating Toll-like receptor 4 signaling pathways in murine peritoneal exudate macrophages.
Journal: International immunopharmacology 20050501
Title: Expression of progesterone receptor B is associated with G0/G1 arrest of the cell cycle and growth inhibition in NIH3T3 cells.
Journal: Experimental cell research 20050501
Title: Histamine H4 receptor stimulation suppresses IL-12p70 production and mediates chemotaxis in human monocyte-derived dendritic cells.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20050501
Title: Atorvastatin induces T cell anergy via phosphorylation of ERK1.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20050501
Title: Activation of protease-activated receptor-1 triggers astrogliosis after brain injury.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050427
Title: ERK1/2-dependent regulation of U937 cell survival after exposure to peroxynitrite.
Journal: Biochemical and biophysical research communications 20050422
Title: Magnetic resonance spectroscopy monitoring of mitogen-activated protein kinase signaling inhibition.
Journal: Cancer research 20050415
Title: Pharmacological inhibitors of extracellular signal-regulated protein kinases attenuate the apoptotic action of cisplatin in human myeloid leukemia cells via glutathione-independent reduction in intracellular drug accumulation.
Journal: Biochimica et biophysica acta 20050415
Title: Statins potentiate the IFN-gamma-induced upregulation of group IIA phospholipase A2 in human aortic smooth muscle cells and HepG2 hepatoma cells.
Journal: Biochimica et biophysica acta 20050415
Title: TGF-beta3 regulates anchoring junction dynamics in the seminiferous epithelium of the rat testis via the Ras/ERK signaling pathway: An in vivo study.
Journal: Developmental biology 20050415
Title: Functional characterization of human RSK4, a new 90-kDa ribosomal S6 kinase, reveals constitutive activation in most cell types.
Journal: The Journal of biological chemistry 20050408
Title: Evaluation of the role of c-Src and ERK in TCDD-dependent release from contact-inhibition in WB-F344 cells.
Journal: Archives of toxicology 20050401
Title: Src family kinase inhibitors block amphiregulin-mediated autocrine ErbB signaling in normal human keratinocytes.
Journal: Molecular pharmacology 20050401
Title: Phorbol ester phorbol-12-myristate-13-acetate promotes anchorage-independent growth and survival of melanomas through MEK-independent activation of ERK1/2.
Journal: Biochemical and biophysical research communications 20050401
Title: Ligand activated relaxin receptor increases the transcription of IGFBP-1 and prolactin in human decidual and endometrial stromal cells.
Journal: Molecular human reproduction 20050401
Title: N-methyl-D-aspartate and TrkB receptors protect neurons against glutamate excitotoxicity through an extracellular signal-regulated kinase pathway.
Journal: Journal of neuroscience research 20050401
Title: Differential effects of all-trans-retinoic acid (RA) on Erk1/2 phosphorylation and cAMP accumulation in normal and malignant human prostate epithelial cells: Erk1/2 inhibition restores RA-induced decrease of cell growth in malignant prostate cells.
Journal: European journal of endocrinology 20050401
Title: The ability of axons to regenerate their growth cones depends on axonal type and age, and is regulated by calcium, cAMP and ERK.
Journal: The European journal of neuroscience 20050401
Title: ERK-dependent induction of TNFalpha expression by the environmental contaminant benzo(a)pyrene in primary human macrophages.
Journal: FEBS letters 20050328
Title: ERK1/2 are involved in low potassium-induced apoptotic signaling downstream of ASK1-p38 MAPK pathway in cultured cerebellar granule neurons.
Journal: Brain research 20050321
Title: Platelet-derived growth factor stimulates Src-dependent mRNA stabilization of specific early genes in fibroblasts.
Journal: The Journal of biological chemistry 20050318
Title: Regulation of bidirectional melanosome transport by organelle bound MAP kinase.
Journal: Current biology : CB 20050308
Title: Phorbol 12-myristate 13-acetate induces epidermal growth factor receptor transactivation via protein kinase Cdelta/c-Src pathways in glioblastoma cells.
Journal: The Journal of biological chemistry 20050304
Title: Neurotensin and EGF induce synergistic stimulation of DNA synthesis by increasing the duration of ERK signaling in ductal pancreatic cancer cells.
Journal: Journal of cellular physiology 20050301
Title: Transfected beta3- but not beta2-adrenergic receptors regulate cystic fibrosis transmembrane conductance regulator activity via a new pathway involving the mitogen-activated protein kinases extracellular signal-regulated kinases.
Journal: Molecular pharmacology 20050301
Title: BH(4) (tetrahydrobiopterin)-dependent activation, but not the expression, of inducible NOS (nitric oxide synthase)-2 in proinflammatory cytokine-stimulated, cultured normal human astrocytes is mediated by MEK-ERK kinases.
Journal: Journal of cellular biochemistry 20050301
Title: Fer kinase sustains the activation level of ERK1/2 and increases the production of VEGF in hypoxic cells.
Journal: Cellular signalling 20050301
Title: Mitogen-activated protein kinase mediates luteinizing hormone-induced breakdown of communication and oocyte maturation in rat ovarian follicles.
Journal: Endocrinology 20050301
Title: Fibroblast growth factor-10 prevents asbestos-induced alveolar epithelial cell apoptosis by a mitogen-activated protein kinase-dependent mechanism.
Journal: American journal of respiratory cell and molecular biology 20050301
Title: HMG-CoA reductase inhibitors, statins, induce phosphorylation of Mdm2 and attenuate the p53 response to DNA damage.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050301
Title: Mouse embryonic stem cells and preimplantation embryos require signaling through the phosphatidylinositol 3-kinase pathway to suppress apoptosis.
Journal: Molecular reproduction and development 20050301
Title: Significant anti-proliferation of human endometrial cancer cells by combined treatment with a selective COX-2 inhibitor NS398 and specific MEK inhibitor U0126.
Journal: International journal of oncology 20050301
Title: A cell-based immunocytochemical assay for monitoring kinase signaling pathways and drug efficacy.
Journal: Analytical biochemistry 20050301
Title: Regulation of Wallerian degeneration and nerve growth factor withdrawal-induced pruning of axons of sympathetic neurons by the proteasome and the MEK/Erk pathway.
Journal: Molecular and cellular neurosciences 20050301
Title: Doxorubicin induces EGF receptor-dependent downregulation of gap junctional intercellular communication in rat liver epithelial cells.
Journal: Biological chemistry 20050301
Title: Neurotoxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin in cerebellar granule cells.
Journal: Experimental & molecular medicine 20050227
Title: ERK kinase inhibition stabilizes the aryl hydrocarbon receptor: implications for transcriptional activation and protein degradation.
Journal: The Journal of biological chemistry 20050211
Title: Calmodulin-dependent kinase kinase/calmodulin kinase I activity gates extracellular-regulated kinase-dependent long-term potentiation.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050202
Title: Two G protein-coupled receptors activate Na+/H+ exchanger isoform 1 in Chinese hamster lung fibroblasts through an ERK-dependent pathway.
Journal: Cellular signalling 20050201
Title: MEK inhibitors block AICAR-induced maturation in mouse oocytes by a MAPK-independent mechanism.
Journal: Molecular reproduction and development 20050201
Title: GDNF-induced leukemia inhibitory factor can mediate differentiation via the MEK/ERK pathway in pheochromocytoma cells derived from nf1-heterozygous knockout mice.
Journal: Experimental cell research 20050201
Title: ERK1 activation is required for S-phase onset and cell cycle progression after fertilization in sea urchin embryos.
Journal: Development (Cambridge, England) 20050201
Title: Central amygdala ERK signaling pathway is critical to incubation of cocaine craving.
Journal: Nature neuroscience 20050201
Title: Disparate expression of IL-12 by SJL/J and B10.S macrophages during Theiler's virus infection is associated with activity of TLR7 and mitogen-activated protein kinases.
Journal: Microbes and infection 20050201
Title: [Mechanisms of antidepressants and serotonin (5-HT)-induced glial cell line-derived neurotrophic factor (GDNF) releases in rat C6 gliobrastoma cells].
Journal: Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20050201
Title: [Involvement of MAPKs and NF-kappaB pathways in Pseudomonas pyocyanin-induced interleukin-8 expression by human airway epithelial cells].
Journal: Wei sheng wu xue bao = Acta microbiologica Sinica 20050201
Title: Pro- and anti-apoptotic roles of c-Jun N-terminal kinase (JNK) in ethanol and acetaldehyde exposed rat hepatocytes.
Journal: European journal of pharmacology 20050131
Title: Role of cell signaling in B[a]P-induced apoptosis: characterization of unspecific effects of cell signaling inhibitors and apoptotic effects of B[a]P metabolites.
Journal: Chemico-biological interactions 20050115
Title: Extracellular signal-regulated kinase1/2 in contraction of vascular smooth muscle.
Journal: Life sciences 20050107
Title: Amphotericin-B-mediated reactivation of latent HIV-1 infection.
Journal: Virology 20050105
Title: PD98059 and U0126 activate AMP-activated protein kinase by increasing the cellular AMP:ATP ratio and not via inhibition of the MAP kinase pathway.
Journal: FEBS letters 20050103
Title: Contribution of phospholipase D in endothelin-1-mediated extracellular signal-regulated kinase activation and proliferation in rat uterine leiomyoma cells.
Journal: Biology of reproduction 20050101
Title: The effect of a brominated flame retardant, tetrabromobisphenol-A, on free radical formation in human neutrophil granulocytes: the involvement of the MAP kinase pathway and protein kinase C.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20050101
Title: Stimulation of catecholamine synthesis by environmental estrogenic pollutants.
Journal: Endocrinology 20050101
Title: Germinal vesicle breakdown is not fully dependent on MAPK activation in maturing oocytes of marine nemertean worms.
Journal: Molecular reproduction and development 20050101
Title: Timing of MAP kinase inactivation effects on emission of polar body in porcine oocytes activated by Ca2+ ionophore.
Journal: Molecular reproduction and development 20050101
Title: Role of ERK1/2 in FSH induced PCNA expression and steroidogenesis in granulosa cells.
Journal: Frontiers in bioscience : a journal and virtual library 20050101
Title: Secreted beta-amyloid precursor protein activates microglia via JNK and p38-MAPK.
Journal: Neurobiology of aging 20050101
Title: Glucagon-like peptide 1 can directly protect the heart against ischemia/reperfusion injury.
Journal: Diabetes 20050101
Title: The involvement of survival signaling pathways in rubella-virus induced apoptosis.
Journal: Virology journal 20050101
Title: Activation of extracellular signal-regulated kinase- mitogen-activated protein kinase cascade in the amygdala is required for memory reconsolidation of auditory fear conditioning.
Journal: The European journal of neuroscience 20050101
Title: Roles of Ras-Erk in apoptosis of PC12 cells induced by trophic factor withdrawal or oxidative stress.
Journal: Journal of molecular neuroscience : MN 20050101
Title: Mevastatin induces apoptosis in HL60 cells dependently on decrease in phosphorylated ERK.
Journal: Molecular and cellular biochemistry 20050101
Title: Role of ERK activation in cisplatin-induced apoptosis in OK renal epithelial cells.
Journal: Journal of applied toxicology : JAT 20050101
Title: Therapeutic targeting of multiple signaling pathways in malignant pleural mesothelioma.
Journal: Oncology 20050101
Title: Mesangial cell apoptosis induced by stimulation of the adenosine A3 receptor: signaling and apoptotic events.
Journal: Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20050101
Title: Pancreatic stellate cells (PSCs) express cyclooxygenase-2 (COX-2) and pancreatic cancer stimulates COX-2 in PSCs.
Journal: Molecular cancer 20050101
Title: Arsenite regulates Cystic Fibrosis Transmembrane Conductance Regulator and P-glycoprotein: evidence of pathway independence.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20050101
Title: Protein kinases mediate increment of the phosphorylation of cyclic AMP-responsive element binding protein in spinal cord of rats following capsaicin injection.
Journal: Molecular pain 20050101
Title: Combining RNA interference and kinase inhibitors against cell signalling components involved in cancer.
Journal: BMC cancer 20050101
Title: Modulation of ERK1/2 activity is crucial for sphingosine-induced death of glioma C6 cells.
Journal: Acta biochimica Polonica 20050101
Title: p21WAF1 expression induced by MEK/ERK pathway activation or inhibition correlates with growth arrest, myogenic differentiation and onco-phenotype reversal in rhabdomyosarcoma cells.
Journal: Molecular cancer 20050101
Title: Extracellular zinc triggers ERK-dependent activation of Na+/H+ exchange in colonocytes mediated by the zinc-sensing receptor.
Journal: The Journal of biological chemistry 20041210
Title: Sinusoidal length oscillation- and receptor-mediated mRNA expression of myosin isoforms and alpha-SM actin in airway smooth muscle.
Journal: American journal of physiology. Cell physiology 20041201
Title: Involvement of extracellular signal-regulated kinase/mitogen-activated protein kinase pathway in multidrug resistance induced by HBx in hepatoma cell line.
Journal: World journal of gastroenterology 20041201
Title: Extracellular signal-regulated kinase induces cyclin D1 and Cdk-2 expression and phosphorylation of retinoblastoma in hepatocellular carcinoma.
Journal: International journal of oncology 20041201
Title: Vav transformation requires activation of multiple GTPases and regulation of gene expression.
Journal: Molecular cancer research : MCR 20041201
Title: Regulated expression of galectin-1 during T-cell activation involves Lck and Fyn kinases and signaling through MEK1/ERK, p38 MAP kinase and p70S6 kinase.
Journal: Molecular and cellular biochemistry 20041201
Title: Role of MAPK/ERK in neurotrophin-4 potentiation of necrotic neuronal death.
Journal: Neurochemical research 20041201
Title: KR-31378 protects cardiac H9c2 cells from chemical hypoxia-induced cell death via inhibition of JNK/p38 MAPK activation.
Journal: The Japanese journal of physiology 20041201
Title: Resistin promotes smooth muscle cell proliferation through activation of extracellular signal-regulated kinase 1/2 and phosphatidylinositol 3-kinase pathways.
Journal: Circulation 20041123
Title: Cystathionine gamma-lyase overexpression inhibits cell proliferation via a H2S-dependent modulation of ERK1/2 phosphorylation and p21Cip/WAK-1.
Journal: The Journal of biological chemistry 20041119
Title: Transactivation of epidermal growth factor receptor mediates catecholamine-induced growth of vascular smooth muscle.
Journal: Circulation research 20041112
Title: Plasticity in the entorhinal cortex suppresses memory for contextual fear.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20041110
Title: Role of mitogen-activated protein kinase activation in injured and intact primary afferent neurons for mechanical and heat hypersensitivity after spinal nerve ligation.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20041110
Title: The functional consequences of cross-talk between the vitamin D receptor and ERK signaling pathways are cell-specific.
Journal: The Journal of biological chemistry 20041105
Title: Inactivation of glycogen synthase kinase-3beta protects against kainic acid-induced neurotoxicity in vivo.
Journal: Brain research 20041105
Title: Mitogenic activity of estrogens in human breast cancer cells does not rely on direct induction of mitogen-activated protein kinase/extracellularly regulated kinase or phosphatidylinositol 3-kinase.
Journal: Molecular endocrinology (Baltimore, Md.) 20041101
Title: Downregulation of osteoblast markers and induction of the glial fibrillary acidic protein by oncostatin M in osteosarcoma cells require PKCdelta and STAT3.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20041101
Title: Role of extracellular signal-regulated protein kinase in neuronal cell death induced by glutathione depletion in neuron/glia mesencephalic cultures.
Journal: Journal of neurochemistry 20041101
Title: Roles of mitogen activated protein kinases and EGF receptor in arsenite-stimulated matrix metalloproteinase-9 production.
Journal: Toxicology and applied pharmacology 20041101
Title: Hyperforin, the active component of St. John's wort, induces IL-8 expression in human intestinal epithelial cells via a MAPK-dependent, NF-kappaB-independent pathway.
Journal: Journal of clinical immunology 20041101
Title: Molecular cross-talk between MEK1/2 and mTOR signaling during recovery of 293 cells from hypertonic stress.
Journal: The Journal of biological chemistry 20041029
Title: Extracellular signal-regulated kinase activation and Bcl-2 downregulation mediate apoptosis after gemcitabine treatment partly via a p53-independent pathway.
Journal: European journal of pharmacology 20041019
Title: Sphingosine 1-phosphate stimulates smooth muscle cell differentiation and proliferation by activating separate serum response factor co-factors.
Journal: The Journal of biological chemistry 20041008
Title: Insulin-like growth factor-1 regulates endogenous RUNX2 activity in endothelial cells through a phosphatidylinositol 3-kinase/ERK-dependent and Akt-independent signaling pathway.
Journal: The Journal of biological chemistry 20041008
Title: Asbestos induces tissue factor in Beas-2B cells via PI3 kinase-PKC-mediated signaling.
Journal: Journal of toxicology and environmental health. Part A 20041008
Title: Clustering of cellular prion protein induces ERK1/2 and stathmin phosphorylation in GT1-7 neuronal cells.
Journal: FEBS letters 20041008
Title: Hypoxia-responsive growth factors upregulate periostin and osteopontin expression via distinct signaling pathways in rat pulmonary arterial smooth muscle cells.
Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20041001
Title: Extracellular signal-regulated kinases are involved in the acute activation of steroidogenesis in immature rat Leydig cells by human chorionic gonadotropin.
Journal: Endocrinology 20041001
Title: Mechanical stimulation and mitogen-activated protein kinase signaling independently regulate osteogenic differentiation and mineralization by calcifying vascular cells.
Journal: Journal of biomechanics 20041001
Title: Modulation of the transactivation function of nuclear factor-kappaB by lipopolysaccharide in RAW264.7 macrophages.
Journal: International journal of oncology 20041001
Title: Constitutive activation of the MEK/ERK pathway mediates all effects of oncogenic H-ras expression in primary erythroid progenitors.
Journal: Blood 20040915
Title: Characterization of the bone morphogenetic protein (BMP) system in human pulmonary arterial smooth muscle cells isolated from a sporadic case of primary pulmonary hypertension: roles of BMP type IB receptor (activin receptor-like kinase-6) in the mitotic action.
Journal: Endocrinology 20040901
Title: Both mitogen-activated protein kinase and phosphatidylinositol 3-kinase signalling are required in epidermal growth factor-induced human trophoblast migration.
Journal: Molecular human reproduction 20040901
Title: Inflammation persistently enhances nocifensive behaviors mediated by spinal group I mGluRs through sustained ERK activation.
Journal: Pain 20040901
Title: EGF-induced trophoblast secretion of MMP-9 and TIMP-1 involves activation of both PI3K and MAPK signalling pathways.
Journal: Reproduction (Cambridge, England) 20040901
Title: Different contributions of STAT3, ERK1/2, and PI3-K signaling to cardiomyocyte hypertrophy by cardiotrophin-1.
Journal: Acta pharmacologica Sinica 20040901
Title: Erk1/2 but not PI3K pathway is required for neurotrophin 3-induced oligodendrocyte differentiation of post-natal neural stem cells.
Journal: Journal of neurochemistry 20040901
Title: Effects of inhibitors of the tyrosine signalling cascade on antigen challenge of guinea pig airways in vitro.
Journal: Annals of the Academy of Medicine, Singapore 20040901
Title: Sphingosine 1-phosphate cross-activates the Smad signaling cascade and mimics transforming growth factor-beta-induced cell responses.
Journal: The Journal of biological chemistry 20040820
Title: Involvement of MAP-kinase, PI3-kinase and EGF-receptor in the stimulatory effect of Neurotensin on DNA synthesis in PC3 cells.
Journal: Regulatory peptides 20040815
Title: p21(Cip-1/SDI-1/WAF-1) expression via the mitogen-activated protein kinase signaling pathway in insulin-induced chondrogenic differentiation of ATDC5 cells.
Journal: Biochemical and biophysical research communications 20040806
Title: Solution phase parallel synthesis and evaluation of MAPK inhibitory activities of close structural analogues of a Ras pathway modulator.
Journal: Bioorganic & medicinal chemistry letters 20040802
Title: Estrogen increases retrograde labeling of motoneurons: evidence of a nongenomic mechanism.
Journal: American journal of physiology. Cell physiology 20040801
Title: Erk1/2 phosphorylation and reactive oxygen species formation via nitric oxide and Akt-1/Raf-1 crosstalk in cultured rat cerebellar granule cells exposed to the organic solvent 1,2,4-trimethylcyclohexane.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20040801
Title: PDGF and FGF induce focal adhesion kinase (FAK) phosphorylation at Ser-910: dissociation from Tyr-397 phosphorylation and requirement for ERK activation.
Journal: Journal of cellular physiology 20040801
Title: PAI-1 expression is required for epithelial cell migration in two distinct phases of in vitro wound repair.
Journal: Journal of cellular physiology 20040801
Title: Inhibitor of p42/44 mitogen-activated protein kinase, but not p38 MAPK, attenuated antigen challenge of guinea pig airways in vitro.
Journal: International immunopharmacology 20040801
Title: Ghrelin exerts a proliferative effect on a rat pituitary somatotroph cell line via the mitogen-activated protein kinase pathway.
Journal: European journal of endocrinology 20040801
Title: [Overexpression of HER2/neu downregulates wild p53 protein expression via PI3K and Ras/Raf/MEK/ERK pathways in human breast cancer cells].
Journal: Zhonghua bing li xue za zhi = Chinese journal of pathology 20040801
Title: Extracellular oxidation by taurine chloramine activates ERK via the epidermal growth factor receptor.
Journal: The Journal of biological chemistry 20040730
Title: Acquired dendritic channelopathy in temporal lobe epilepsy.
Journal: Science (New York, N.Y.) 20040723
Title: Aggravation of necrotic death of glucose-deprived cells by the MEK1 inhibitors U0126 and PD184161 through depletion of ATP.
Journal: Biochemical pharmacology 20040715
Title: Bcl-x(S) induces an NGF-inhibitable cytochrome c release.
Journal: Experimental cell research 20040715
Title: Hepatocyte growth factor promotes cell proliferation and inhibits progesterone secretion via PKA and MAPK pathways in a human granulosa cell line.
Journal: Molecular reproduction and development 20040701
Title: Raf promotes human herpesvirus-8 (HHV-8/KSHV) infection.
Journal: Oncogene 20040701
Title: Hepatitis B viral HBx induces matrix metalloproteinase-9 gene expression through activation of ERK and PI-3K/AKT pathways: involvement of invasive potential.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040701
Title: Increased IL-1beta in cortex of aged rats is accompanied by downregulation of ERK and PI-3 kinase.
Journal: Neurobiology of aging 20040701
Title: Regulation of metalloproteinases and NF-kappaB activation in rabbit synovial fibroblasts via E prostaglandins and Erk: contrasting effects of nabumetone and 6MNA.
Journal: British journal of pharmacology 20040701
Title: Prolonged extracellular signal-regulated kinase 1/2 activation during fibroblast growth factor 1- or heregulin beta1-induced antiestrogen-resistant growth of breast cancer cells is resistant to mitogen-activated protein/extracellular regulated kinase kinase inhibitors.
Journal: Cancer research 20040701
Title: Activation of protein kinase C betaII/epsilon-c-Jun NH2-terminal kinase pathway and inhibition of mitogen-activated protein/extracellular signal-regulated kinase 1/2 phosphorylation in antitumor invasive activity induced by the polymethoxy flavonoid, nobiletin.
Journal: Molecular cancer therapeutics 20040701
Title: Conjugated linoleic acid induces human adipocyte delipidation: autocrine/paracrine regulation of MEK/ERK signaling by adipocytokines.
Journal: The Journal of biological chemistry 20040618
Title: Tissue factor binding of activated factor VII triggers smooth muscle cell proliferation via extracellular signal-regulated kinase activation.
Journal: Circulation 20040615
Title: Overexpression of HER2 (erbB2) in human breast epithelial cells unmasks transforming growth factor beta-induced cell motility.
Journal: The Journal of biological chemistry 20040604
Title: Hypoxia augments TNF-alpha-mediated endothelin-1 release and cell proliferation in human optic nerve head astrocytes.
Journal: Biochemical and biophysical research communications 20040604
Title: Fcgamma receptor signaling in primary human microglia: differential roles of PI-3K and Ras/ERK MAPK pathways in phagocytosis and chemokine induction.
Journal: Journal of leukocyte biology 20040601
Title: A hierarchical order of factors in the generation of FLK1- and SCL-expressing hematopoietic and endothelial progenitors from embryonic stem cells.
Journal: Development (Cambridge, England) 20040601
Title: Anti-inflammatory effects of mitogen-activated protein kinase kinase inhibitor U0126 in an asthma mouse model.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20040601
Title: Retrograde amnesia induced by drugs acting on different molecular systems.
Journal: Behavioral neuroscience 20040601
Title: Neuronal activation of Ras regulates synaptic connectivity.
Journal: The European journal of neuroscience 20040601
Title: Dominant-negative c-Jun (TAM67) target genes: HMGA1 is required for tumor promoter-induced transformation.
Journal: Oncogene 20040527
Title: Protein kinase C (PKC) betaII induces cell invasion through a Ras/Mek-, PKC iota/Rac 1-dependent signaling pathway.
Journal: The Journal of biological chemistry 20040521
Title: Mineralocorticoid receptor antagonists do not block rapid ERK activation by aldosterone.
Journal: Biochemical and biophysical research communications 20040521
Title: Short-chain fatty acids enhance nuclear receptor activity through mitogen-activated protein kinase activation and histone deacetylase inhibition.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20040504
Title: Regulation of macrophage cyclooxygenase-2 gene expression by modifications of histone H3.
Journal: American journal of physiology. Lung cellular and molecular physiology 20040501
Title: The role of activated MEK-ERK pathway in quercetin-induced growth inhibition and apoptosis in A549 lung cancer cells.
Journal: Carcinogenesis 20040501
Title: Evidence for the involvement of protein kinase C in acidic pH-induced contraction in spontaneously hypertensive rat aorta.
Journal: Pharmacology 20040501
Title: Potential roles of NF-kappaB and ERK1/2 in cytoprotection against oxidative cell death induced by tetrahydropapaveroline.
Journal: Free radical biology & medicine 20040501
Title: Activation of extracellular signal-regulated protein kinase in dorsal horn neurons in the rat neuropathic intermittent claudication model.
Journal: Pain 20040501
Title: BMK1 is activated in glomeruli of diabetic rats and in mesangial cells by high glucose conditions.
Journal: Kidney international 20040501
Title: Role of putative membrane receptors in the effects of estradiol on human vascular cell growth.
Journal: American journal of hypertension 20040501
Title: Transcription factor Ets-1 mediates ischemia- and vascular endothelial growth factor-dependent retinal neovascularization.
Journal: The American journal of pathology 20040501
Title: Extracellular regulated kinase/mitogen activated protein kinase is up-regulated in pulmonary emphysema and mediates matrix metalloproteinase-1 induction by cigarette smoke.
Journal: The Journal of biological chemistry 20040423
Title: Clathrin-mediated endocytosis of Na+,K+-ATPase in response to parathyroid hormone requires ERK-dependent phosphorylation of Ser-11 within the alpha1-subunit.
Journal: The Journal of biological chemistry 20040423
Title: Epidermal growth factor induces fibroblast contractility and motility via a protein kinase C delta-dependent pathway.
Journal: The Journal of biological chemistry 20040409
Title: Expressions of inhibitory Smads, Smad6 and Smad7, are differentially regulated by TPA in human lung fibroblast cells.
Journal: Biochemical and biophysical research communications 20040409
Title: Prostacyclin induces apoptosis of vascular smooth muscle cells by a cAMP-mediated inhibition of extracellular signal-regulated kinase activity and can counteract the mitogenic activity of endothelin-1 or basic fibroblast growth factor.
Journal: Circulation research 20040402
Title: Glycogen synthase kinase-3beta is tyrosine-phosphorylated by MEK1 in human skin fibroblasts.
Journal: Biochemical and biophysical research communications 20040402
Title: Protein kinase C and mitogen-activated protein kinase cascade in mouse cumulus cells: cross talk and effect on meiotic resumption of oocyte.
Journal: Biology of reproduction 20040401
Title: Evidence for nucleotide receptor modulation of cross talk between MAP kinase and NF-kappa B signaling pathways in murine RAW 264.7 macrophages.
Journal: American journal of physiology. Cell physiology 20040401
Title: MAPK signaling pathways modulate IL-1beta expression in human keratinocytes.
Journal: Archives of biochemistry and biophysics 20040401
Title: Influence of interleukin-1 beta induction and mitogen-activated protein kinase phosphorylation on optic nerve ligation-induced matrix metalloproteinase-9 activation in the retina.
Journal: Experimental eye research 20040401
Title: Radiation-induced up-regulation of Mmp2 involves increased mRNA stability, redox modulation, and MAPK activation.
Journal: Radiation research 20040401
Title: Aryl hydrocarbon receptor activation and cytochrome P450 1A induction by the mitogen-activated protein kinase inhibitor U0126 in hepatocytes.
Journal: Molecular pharmacology 20040401
Title: Hypoxia increases resistance of human pancreatic cancer cells to apoptosis induced by gemcitabine.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20040401
Title: Phosphorylation of PML by mitogen-activated protein kinases plays a key role in arsenic trioxide-mediated apoptosis.
Journal: Cancer cell 20040401
Title: Mechanism of human urotensin II-induced contraction in rat aorta.
Journal: Journal of pharmacological sciences 20040401
Title: Manganese potentiates lipopolysaccharide-induced expression of NOS2 in C6 glioma cells through mitochondrial-dependent activation of nuclear factor kappaB.
Journal: Brain research. Molecular brain research 20040330
Title: Beyond U0126. Dianion chemistry leading to the rapid synthesis of a series of potent MEK inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20040322
Title: Overexpression of aldehyde dehydrogenase-2 (ALDH2) transgene prevents acetaldehyde-induced cell injury in human umbilical vein endothelial cells: role of ERK and p38 mitogen-activated protein kinase.
Journal: The Journal of biological chemistry 20040319
Title: Ras/MEK pathway is required for NGF-induced expression of tyrosine hydroxylase gene.
Journal: Biochemical and biophysical research communications 20040305
Title: Mechanisms of shear stress-induced endothelial nitric-oxide synthase phosphorylation and expression in ovine fetoplacental artery endothelial cells.
Journal: Biology of reproduction 20040301
Title: Overexpression of phospholipase D prevents actinomycin D-induced apoptosis through potentiation of phosphoinositide 3-kinase signalling pathways in Chinese-hamster ovary cells.
Journal: The Biochemical journal 20040301
Title: Signaling pathways regulating interleukin-13-stimulated chemokine release from airway smooth muscle.
Journal: American journal of respiratory and critical care medicine 20040301
Title: PDGF-BB enhances alpha1beta1 integrin-mediated activation of the ERK/AP-1 pathway involved in collagen matrix remodeling by rat mesangial cells.
Journal: Journal of cellular physiology 20040301
Title: Examination of the signal transduction pathways involved in matrix metalloproteinases-2 in human pulp cells.
Journal: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20040301
Title: Reciprocal regulation of beta-adrenergic receptor mRNA stability by mitogen activated protein kinase activation and inhibition.
Journal: Molecular and cellular biochemistry 20040301
Title: Thombospondin-1 disrupts estrogen-induced endothelial cell proliferation and migration and its expression is suppressed by estradiol.
Journal: Molecular cancer research : MCR 20040301
Title: WNK1 activates ERK5 by an MEKK2/3-dependent mechanism.
Journal: The Journal of biological chemistry 20040227
Title: bcl-2 induction of urokinase plasminogen activator receptor expression in human cancer cells through Sp1 activation: involvement of ERK1/ERK2 activity.
Journal: The Journal of biological chemistry 20040220
Title: Differentiation-inducing factor-1-induced growth arrest of K562 leukemia cells involves the reduction of ERK1/2 activity.
Journal: European journal of pharmacology 20040206
Title: Endothelin-1 promotes phosphorylation of CREB transcription factor in primary cultures of neonatal rat cardiac myocytes: implications for the regulation of c-jun expression.
Journal: Biochimica et biophysica acta 20040202
Title: Novel action of activin and bone morphogenetic protein in regulating aldosterone production by human adrenocortical cells.
Journal: Endocrinology 20040201
Title: Molecular mechanism of nucleotide-induced primary granule release in human neutrophils: role for the P2Y2 receptor.
Journal: American journal of physiology. Cell physiology 20040201
Title: Astroglial regulation of apolipoprotein E expression in neuronal cells. Implications for Alzheimer's disease.
Journal: The Journal of biological chemistry 20040130
Title: 12-O-tetradecanoylphorbol-13-acetate may both potentiate and decrease the generation of apoptosis by the antileukemic agent arsenic trioxide in human promonocytic cells. Regulation by extracellular signal-regulated protein kinases and glutathione.
Journal: The Journal of biological chemistry 20040130
Title: Anisomycin superinduces annexin V mRNA expression through the ERK1/2 but not the p38 MAP kinase pathway.
Journal: Biochemical and biophysical research communications 20040123
Title: Src-dependent ERK5 and Src/EGFR-dependent ERK1/2 activation is required for cell proliferation by asbestos.
Journal: Oncogene 20040122
Title: Inhibition of MEK/ERK 1/2 pathway reduces pro-inflammatory cytokine interleukin-1 expression in focal cerebral ischemia.
Journal: Brain research 20040116
Title: Potent, selective and cell-mediated inhibition of human herpesvirus 6 at an early stage of viral replication by the non-nucleoside compound CMV423.
Journal: Biochemical pharmacology 20040115
Title: Temporal control of NF-kappaB activation by ERK differentially regulates interleukin-1beta-induced gene expression.
Journal: The Journal of biological chemistry 20040109
Title: Differential activation of the luteinizing hormone beta-subunit promoter by activin and gonadotropin-releasing hormone: a role for the mitogen-activated protein kinase signaling pathway in LbetaT2 gonadotrophs.
Journal: Biology of reproduction 20040101
Title: Anthocyanidins inhibit activator protein 1 activity and cell transformation: structure-activity relationship and molecular mechanisms.
Journal: Carcinogenesis 20040101
Title: Activation of the Raf-1/MEK/Erk kinase pathway by a novel Cdc25 inhibitor in human prostate cancer cells.
Journal: The Prostate 20040101
Title: Role of putative membrane receptors in the effect of androgens on human vascular cell growth.
Journal: The Journal of endocrinology 20040101
Title: Angiotensin II induces endothelin-1 gene expression via extracellular signal-regulated kinase pathway in rat aortic smooth muscle cells.
Journal: Cardiovascular research 20040101
Title: IFN-gamma gene expression in epithelial trophectoderm cells is linked to downregulation of the p44/p42 MAP kinase pathway.
Journal: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20040101
Title: PI3 kinase is important for Ras, MEK and Erk activation of Epo-stimulated human erythroid progenitors.
Journal: BMC biology 20040101
Title: Activation of extracellular signal-regulated protein kinase in the dorsal root ganglion following inflammation near the nerve cell body.
Journal: Neuroscience 20040101
Title: MAP kinase activation by fluoxetine and its relation to gene expression in cultured rat astrocytes.
Journal: Journal of molecular neuroscience : MN 20040101
Title: Angiotensin II regulation of TGF-beta in murine mesangial cells involves both PI3 kinase and MAP kinase.
Journal: Annals of clinical and laboratory science 20040101
Title: Involvement of ERK1/2 and p38 MAP kinase in doxorubicin-induced uPA expression in human RC-K8 lymphoma and NCI-H69 small cell lung carcinoma cells.
Journal: Oncology 20040101
Title: Constitutively active Galpha16 stimulates STAT3 via a c-Src/JAK- and ERK-dependent mechanism.
Journal: The Journal of biological chemistry 20031226
Title: Pretreatment with PKC inhibitor triggers TNF-alpha induced apoptosis in TNF-alpha-resistant B16 melanoma BL6 cells.
Journal: Life sciences 20031226
Title: The MEK-1/ERKs signalling pathway is differentially involved in the self-renewal of early and late avian erythroid progenitor cells.
Journal: Oncogene 20031218
Title: Xp42(Mpk1) activation is not required for germinal vesicle breakdown but for Raf complete phosphorylation in insulin-stimulated Xenopus oocytes.
Journal: The Journal of biological chemistry 20031212
Title: Angiotensin II signaling pathways mediate expression of cardiac T-type calcium channels.
Journal: Circulation research 20031212
Title: Cadmium induces nuclear export of Bach1, a transcriptional repressor of heme oxygenase-1 gene.
Journal: The Journal of biological chemistry 20031205
Title: Reprogramming of bovine somatic cell nuclei is not directly regulated by maturation promoting factor or mitogen-activated protein kinase activity.
Journal: Biology of reproduction 20031201
Title: IGF-I stimulates IL-8 production in the promyelocytic cell line HL-60 through activation of extracellular signal-regulated protein kinase.
Journal: Cellular signalling 20031201
Title: 1,10-Phenanthroline phosphorylates (activates) MAP kinase in Xenopus oocytes.
Journal: Cellular signalling 20031201
Title: Novel combination of cyclooxygenase-2 and MEK inhibitors in human hepatocellular carcinoma provides a synergistic increase in apoptosis.
Journal: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20031201
Title: Modulation of nerve growth factor-induced activation of MAP kinase in PC12 cells by inhibitors of nitric oxide synthase.
Journal: Journal of neurochemistry 20031201
Title: Ebselen inhibits NO-induced apoptosis of differentiated PC12 cells via inhibition of ASK1-p38 MAPK-p53 and JNK signaling and activation of p44/42 MAPK and Bcl-2.
Journal: Journal of neurochemistry 20031201
Title: An investigation of the MEK/ERK inhibitor U0126 in acute myeloid leukemia.
Journal: Annals of the New York Academy of Sciences 20031201
Title: MITF-M plays an essential role in transcriptional activation and signal transduction in Xiphophorus melanoma.
Journal: Gene 20031127
Title: ERK inhibitor PD98059 enhances docetaxel-induced apoptosis of androgen-independent human prostate cancer cells.
Journal: International journal of cancer 20031110
Title: Enhanced expression and activation of CTP:phosphocholine cytidylyltransferase beta2 during neurite outgrowth.
Journal: The Journal of biological chemistry 20031107
Title: IGF-1 inhibits the mitochondrial apoptosis program in mesangial cells exposed to high glucose.
Journal: American journal of physiology. Renal physiology 20031101
Title: MEK inhibition of pancreatic carcinoma cells by U0126 and its effect in combination with sulindac.
Journal: Pancreas 20031101
Title: Dopamine D1 receptors mediate CREB phosphorylation via phosphorylation of the NMDA receptor at Ser897-NR1.
Journal: Journal of neurochemistry 20031101
Title: Synchronous activation of ERK and phosphatidylinositol 3-kinase pathways is required for collagen and extracellular matrix production in keloids.
Journal: The Journal of biological chemistry 20031017
Title: Proteomic profiling drug-induced apoptosis in non-small cell lung carcinoma: identification of RS/DJ-1 and RhoGDIalpha.
Journal: Cancer research 20031015
Title: A new bisphosphonate, YM529 induces apoptosis in HL60 cells by decreasing phosphorylation of single survival signal ERK.
Journal: Life sciences 20031010
Title: Improvement in fear memory by histamine-elicited ERK2 activation in hippocampal CA3 cells.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20031008
Title: Neutrophil elastase stimulates human airway epithelial cells to produce PGE2 through activation of p44/42 MAPK and upregulation of cyclooxygenase-2.
Journal: American journal of physiology. Lung cellular and molecular physiology 20031001
Title: Association of sustained ERK activity with integrin beta3 induction during receptor activator of nuclear factor kappaB ligand (RANKL)-directed osteoclast differentiation.
Journal: Experimental cell research 20031001
Title: A sensitive dual-fluorescence reporter system enables positive selection of ras suppressors by suppression of ras-induced apoptosis.
Journal: Cancer gene therapy 20031001
Title: Effects of extracellular signal-regulated kinase (ERK) on focal cerebral ischemia.
Journal: Chinese medical journal 20031001
Title: Preferential killing of PTEN-null myelomas by PI3K inhibitors through Akt pathway.
Journal: Oncogene 20030918
Title: Fibroblast growth factor receptor-1 is essential for in vitro cardiomyocyte development.
Journal: Circulation research 20030905
Title: IL-13-induced changes in the goblet cell density of human bronchial epithelial cell cultures: MAP kinase and phosphatidylinositol 3-kinase regulation.
Journal: American journal of physiology. Lung cellular and molecular physiology 20030901
Title: Extracellular signal-regulated kinases and contractile responses in ovine adult and fetal cerebral arteries.
Journal: The Journal of physiology 20030901
Title: Kinase-dependent loss of Na+ channel slow-inactivation in rat CA1 hippocampal pyramidal cell dendrites after brief exposure to convulsants.
Journal: The European journal of neuroscience 20030901
Title: Inhibition of p38 mitogen-activated protein kinase interferes with cell shape changes and gene expression associated with Schwann cell myelination.
Journal: Experimental neurology 20030901
Title: Adaptive hypersensitivity following long-term estrogen deprivation: involvement of multiple signal pathways.
Journal: The Journal of steroid biochemistry and molecular biology 20030901
Title: Stimulation of the plasma membrane Na+/H+ exchanger NHE1 by sustained intracellular acidosis. Evidence for a novel mechanism mediated by the ERK pathway.
Journal: The Journal of biological chemistry 20030822
Title: Extracellular signaling-regulated kinase-1 and -2 (ERK 1/2) mediate referred hyperalgesia in a murine model of visceral pain.
Journal: Brain research. Molecular brain research 20030819
Title: PI3K inhibitors changed the p53-induced response of Saos-2 cells from growth arrest to apoptosis.
Journal: Biochemical and biophysical research communications 20030815
Title: TNF-alpha induction of lipolysis is mediated through activation of the extracellular signal related kinase pathway in 3T3-L1 adipocytes.
Journal: Journal of cellular biochemistry 20030815
Title: Transcriptional profiling of targets for combination therapy of lung carcinoma with paclitaxel and mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor.
Journal: Cancer research 20030815
Title: Hypertonic induction of COX-2 expression in renal medullary epithelial cells requires transactivation of the EGFR.
Journal: American journal of physiology. Renal physiology 20030801
Title: Phosphorylation of initiation factor 4E is resistant to SB203580 in cells expressing a drug-resistant mutant of stress-activated protein kinase 2a/p38.
Journal: Cellular signalling 20030801
Title: A dual, non-redundant, role for LIF as a regulator of development and STAT3-mediated cell death in mammary gland.
Journal: Development (Cambridge, England) 20030801
Title: Divergence in signaling pathways involved in promotion of cell viability mediated by bFGF, NGF, and EGF in PC12 cells.
Journal: Neurochemical research 20030801
Title: Ouabain is a potent promoter of growth and activator of ERK1/2 in ouabain-resistant rat renal epithelial cells.
Journal: The Journal of biological chemistry 20030725
Title: The extracellular signal-regulated kinase cascade suppresses amyloid beta protein-induced promotion of glutamate clearance in cultured rat cortical astrocytes.
Journal: Brain research 20030725
Title: Epidermal growth factor inhibition of c-Myc-mediated apoptosis through Akt and Erk involves Bcl-xL upregulation in mammary epithelial cells.
Journal: Experimental cell research 20030715
Title: Mechanical stress-induced apoptosis of endplate chondrocytes in organ-cultured mouse intervertebral discs: an ex vivo study.
Journal: Spine 20030715
Title: Involvement of MAP kinases in TGF-beta-stimulated vascular endothelial growth factor synthesis in osteoblasts.
Journal: Archives of biochemistry and biophysics 20030701
Title: Effects of GDNF on 6-OHDA-induced death in a dopaminergic cell line: modulation by inhibitors of PI3 kinase and MEK.
Journal: Journal of neuroscience research 20030701
Title: Involvement of p38 MAPK, JNK, p42/p44 ERK and NF-kappaB in IL-1beta-induced chemokine release in human airway smooth muscle cells.
Journal: Respiratory medicine 20030701
Title: Inhibition of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase enhances chemotherapeutic effects on H460 human non-small cell lung cancer cells through activation of apoptosis.
Journal: Molecular cancer therapeutics 20030701
Title: MAPK is involved in metaphase I arrest in oyster and mussel oocytes.
Journal: Biology of the cell 20030701
Title: Fibroblast growth factor-10 upregulates Na,K-ATPase via the MAPK pathway.
Journal: FEBS letters 20030619
Title: Aspirin-triggered lipoxin A4 and B4 analogs block extracellular signal-regulated kinase-dependent TNF-alpha secretion from human T cells.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20030615
Title: Caspase 3 activation is essential for efficient influenza virus propagation.
Journal: The EMBO journal 20030602
Title: Role of MAPK pathways in light chain-induced cytokine production in human proximal tubule cells.
Journal: American journal of physiology. Renal physiology 20030601
Title: p38 MAP kinase regulates BMP-4-stimulated VEGF synthesis via p70 S6 kinase in osteoblasts.
Journal: American journal of physiology. Endocrinology and metabolism 20030601
Title: 14-3-3gamma is upregulated by in vitro ischemia and binds to protein kinase Raf in primary cultures of astrocytes.
Journal: Glia 20030601
Title: Secretion of matrix metalloproteinase-9 by the proinflammatory cytokine, IL-1beta: a role for the dual signalling pathways, Akt and Erk.
Journal: Genes to cells : devoted to molecular & cellular mechanisms 20030601
Title: CX-659S, a diaminouracil derivative, indirectly inhibits the function of Langerhans cells by blocking the MEK1/2-Erk1/2 pathway in keratinocytes.
Journal: The Journal of investigative dermatology 20030601
Title: Extracellular signal-regulated kinase 1/2 is involved in the activation of NADPH oxidase induced by FMLP receptor but not by complement receptor 3 in rat neutrophils.
Journal: Free radical research 20030601
Title: Regulation of leptin on insulin secretion and sulfonulurea receptor 1 transcription level in isolated rats pancreatic islets.
Journal: Chinese medical journal 20030601
Title: Integrin alpha2 and extracellular signal-regulated kinase are functionally linked in highly malignant autocrine transforming growth factor-alpha-driven colon cancer cells.
Journal: The Journal of biological chemistry 20030530
Title: An absolute role of the PKC-dependent NF-kappaB activation for induction of MMP-9 in hepatocellular carcinoma cells.
Journal: Biochemical and biophysical research communications 20030530
Title: Neurotensin stimulates protein kinase C-dependent mitogenic signaling in human pancreatic carcinoma cell line PANC-1.
Journal: Cancer research 20030515
Title: AhR- and ERK-dependent pathways function synergistically to mediate 2,3,7,8-tetrachlorodibenzo-p-dioxin suppression of peroxisome proliferator-activated receptor-gamma1 expression and subsequent adipocyte differentiation.
Journal: Toxicology and applied pharmacology 20030515
Title: Differential activation of extracellular signal-regulated protein kinase in primary afferent neurons regulates brain-derived neurotrophic factor expression after peripheral inflammation and nerve injury.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030515
Title: MAP kinase-dependent induction of clock gene expression by alpha 1-adrenergic receptor activation.
Journal: FEBS letters 20030508
Title: Destabilization of Na(v)1.7 sodium channel alpha-subunit mRNA by constitutive phosphorylation of extracellular signal-regulated kinase: negative regulation of steady-state level of cell surface functional sodium channels in adrenal chromaffin cells.
Journal: Molecular pharmacology 20030501
Title: Dependence on electron transport chain function and intracellular signaling of genomic responses in SH-SY5Y cells to the mitochondrial neurotoxin MPP(+).
Journal: Experimental neurology 20030501
Title: Stimulatory effect of prostaglandin F(2alpha) on Na-dependent phosphate transport in osteoblast-like cells.
Journal: Prostaglandins, leukotrienes, and essential fatty acids 20030501
Title: Independent activation of MAP kinase and MPF during the initiation of meiotic maturation in pig oocytes.
Journal: Reproduction (Cambridge, England) 20030501
Title: Phosphatidylinositol 3-kinase regulates the induction of long-term potentiation through extracellular signal-related kinase-independent mechanisms.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030501
Title: Mechanisms involved in the stimulation of prostacyclin synthesis by human lymphocytes in human umbilical vein endothelial cells.
Journal: British journal of pharmacology 20030501
Title: Down-regulation of cell surface CXCR6 expression during T cell activation is predominantly mediated by calcineurin.
Journal: Cellular immunology 20030501
Title: Inhibition of the MEK/ERK pathway has no effect on agonist-induced aggregation of human platelets.
Journal: Biochemical pharmacology 20030415
Title: Tumor promoter arsenite stimulates histone H3 phosphoacetylation of proto-oncogenes c-fos and c-jun chromatin in human diploid fibroblasts.
Journal: The Journal of biological chemistry 20030411
Title: Kinase inhibitors: not just for kinases anymore.
Journal: Journal of medicinal chemistry 20030410
Title: [Pharmacological modulation of the inflammatory response after gunshot injuries in the pig].
Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20030410
Title: Chronic activation of extracellular-signal-regulated protein kinases by phenylephrine is required to elicit a hypertrophic response in cardiac myocytes.
Journal: The Biochemical journal 20030401
Title: Mitogen-activated protein kinase regulates nuclear association of human progesterone receptors.
Journal: Molecular endocrinology (Baltimore, Md.) 20030401
Title: Basic fibroblast growth factor induces the expression of matrix metalloproteinase-3 in human periodontal ligament cells through the MEK2 mitogen-activated protein kinase pathway.
Journal: Journal of periodontal research 20030401
Title: The p42/44mitogen-activated protein kinase inhibitor PD 98059, but not U 0126, increases a K+ current in cardiomyocytes.
Journal: Clinical and experimental pharmacology & physiology 20030401
Title: Circadian and photic regulation of phosphorylation of ERK1/2 and Elk-1 in the suprachiasmatic nuclei of the Syrian hamster.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030401
Title: Combined action of ERK and NF kappa B mediates the protective effect of phorbol ester on Fas-induced apoptosis in Jurkat cells.
Journal: The Journal of biological chemistry 20030328
Title: Transcriptional activation of the NF-kappaB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1).
Journal: The EMBO journal 20030317
Title: Regulation of extracellular signal-regulated kinase by cannabinoids in hippocampus.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030315
Title: Growth differentiation factor-15 prevents low potassium-induced cell death of cerebellar granule neurons by differential regulation of Akt and ERK pathways.
Journal: The Journal of biological chemistry 20030314
Title: Activation of ERK1/2 by deltaRaf-1:ER* represses Bim expression independently of the JNK or PI3K pathways.
Journal: Oncogene 20030306
Title: Characterization of ribosomal S6 protein kinase p90rsk during meiotic maturation and fertilization in pig oocytes: mitogen-activated protein kinase-associated activation and localization.
Journal: Biology of reproduction 20030301
Title: Fluid flow shear stress stimulates human osteoblast proliferation and differentiation through multiple interacting and competing signal transduction pathways.
Journal: Bone 20030301
Title: Proliferation of cancer cells despite CDK2 inhibition.
Journal: Cancer cell 20030301
Title: Identification of the hydroxyl radical and other reactive oxygen species in human neutrophil granulocytes exposed to a fragment of the amyloid beta peptide.
Journal: Free radical research 20030301
Title: The peripheral cannabinoid receptor Cb2, a novel oncoprotein, induces a reversible block in neutrophilic differentiation.
Journal: Blood 20030215
Title: Increased protein stability as a mechanism that enhances Nrf2-mediated transcriptional activation of the antioxidant response element. Degradation of Nrf2 by the 26 S proteasome.
Journal: The Journal of biological chemistry 20030214
Title: Relevance of mitogen activated protein kinase (MAPK) and phosphotidylinositol-3-kinase/protein kinase B (PI3K/PKB) pathways to induction of apoptosis by curcumin in breast cells.
Journal: Biochemical pharmacology 20030201
Title: Sulindac sulfide inhibits epidermal growth factor-induced phosphorylation of extracellular-regulated kinase 1/2 and Bad in human colon cancer cells.
Journal: Cancer research 20030201
Title: Activation of mitogen-activated protein kinase pathway by keratinocyte growth factor or fibroblast growth factor-10 promotes cell proliferation in human endometrial carcinoma cells.
Journal: The Journal of clinical endocrinology and metabolism 20030201
Title: Stimulation of the calcitonin gene-related peptide enhancer by mitogen-activated protein kinases and repression by an antimigraine drug in trigeminal ganglia neurons.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030201
Title: Discussion of the role of the extracellular signal-regulated kinase-phospholipase A2 pathway in production of reactive oxygen species in Alzheimer's disease.
Journal: Neurochemical research 20030201
Title: ERK inhibition attenuates 5-HT-induced contractions in fetal and adult ovine carotid arteries.
Journal: Archives of physiology and biochemistry 20030201
Title: Simvastatin stimulates VEGF release via p44/p42 MAP kinase in vascular smooth muscle cells.
Journal: Biochemical and biophysical research communications 20030131
Title: Insulin stimulation of pyruvate dehydrogenase in adipocytes involves two distinct signalling pathways.
Journal: The Biochemical journal 20030115
Title: Molecular basis of bone morphogenetic protein-15 signaling in granulosa cells.
Journal: The Journal of biological chemistry 20030103
Title: A conserved role for the MEK signalling pathway in neural tissue specification and posteriorisation in the invertebrate chordate, the ascidian Ciona intestinalis.
Journal: Development (Cambridge, England) 20030101
Title: Cyclosporin A induces erythroid differentiation of K562 cells through p38 MAPK and ERK pathways.
Journal: American journal of hematology 20030101
Title: Activation of the MAP kinase pathway induces chicken ovalbumin upstream promoter-transcription factor II (COUP-TFII) expression in human breast cancer cell lines.
Journal: The Journal of endocrinology 20030101
Title: Hydrocortisone and the mitogen-activated protein kinase inhibitor U0126 acutely suppress reactive oxygen species generation from circulating granulocytes after gunshot injuries in the pig.
Journal: Critical care medicine 20030101
Title: A role for ERK MAP kinase in physiologic temporal integration in hippocampal area CA1.
Journal: Learning & memory (Cold Spring Harbor, N.Y.) 20030101
Title: Induction of early growth response gene Egr2 by basic calcium phosphate crystals through a calcium-dependent protein kinase C-independent p44/42 mitogen-activated protein kinase pathway.
Journal: Cells, tissues, organs 20030101
Title: p8 inhibits the growth of human pancreatic cancer cells and its expression is induced through pathways involved in growth inhibition and repressed by factors promoting cell growth.
Journal: Molecular cancer 20030101
Title: Sequence dependent exposure of mammary carcinoma cells to Taxotere and the MEK1/2 inhibitor U0126 causes enhanced cell killing in vitro.
Journal: Cancer biology & therapy 20030101
Title: Docetaxel cytotoxicity is enhanced by inhibition of the Raf/MEK/ERK signal transduction pathway.
Journal: Cancer biology & therapy 20030101
Title: Regulation of Na(+)-K(+)-2Cl- cotransporter activity in rat skeletal muscle and intestinal epithelial cells.
Journal: Tsitologiia 20030101
Title: Participation of Ras and extracellular regulated kinase in the hyperplastic response of middle-ear mucosa during bacterial otitis media.
Journal: The Journal of infectious diseases 20021215
Title: Stimulation of the Raf/MEK/ERK cascade is necessary and sufficient for activation and Thr-160 phosphorylation of a nuclear-targeted CDK2.
Journal: The Journal of biological chemistry 20021206
Title: Dual role for mitogen-activated protein kinase (Erk) in insulin-dependent regulation of Fra-1 (fos-related antigen-1) transcription and phosphorylation.
Journal: The Biochemical journal 20021201
Title: Loss of Rb overrides the requirement for ERK activity for cell proliferation.
Journal: Journal of cell science 20021201
Title: The upregulation of CC chemokine receptor 7 and the increased migration of maturing dendritic cells to macrophage inflammatory protein 3beta and secondary lymphoid chemokine is mediated by the p38 stress-activated protein kinase pathway.
Journal: British journal of haematology 20021201
Title: Progestin and G protein-coupled receptor 30 inhibit mitogen-activated protein kinase activity in MCF-7 breast cancer cells.
Journal: Endocrinology 20021201
Title: Blockades of mitogen-activated protein kinase and calcineurin both change fibre-type markers in skeletal muscle culture.
Journal: Pflugers Archiv : European journal of physiology 20021201
Title: Activation of MEK/ERK signaling promotes adipogenesis by enhancing peroxisome proliferator-activated receptor gamma (PPARgamma ) and C/EBPalpha gene expression during the differentiation of 3T3-L1 preadipocytes.
Journal: The Journal of biological chemistry 20021129
Title: Serum deprivation increases the expression of low density lipoprotein receptor-related protein in primary cultured rat astrocytes.
Journal: Biochemical and biophysical research communications 20021122
Title: Up-regulation of c-jun mRNA in cardiac myocytes requires the extracellular signal-regulated kinase cascade, but c-Jun N-terminal kinases are required for efficient up-regulation of c-Jun protein.
Journal: The Biochemical journal 20021115
Title: Presence of mitogen-activated protein kinase in retinal Müller cells and its neuroprotective effect ischemia-reperfusion injury.
Journal: Neuroreport 20021115
Title: Redistribution of ERK/MAP kinase to uropod-like structures in interleukin-3-induced cell shape changes.
Journal: Immunology letters 20021101
Title: Mitogen-activated protein kinases mediate stretch-induced c-fos mRNA expression in myometrial smooth muscle cells.
Journal: American journal of physiology. Cell physiology 20021101
Title: Ras/Erk signaling is essential for activation of protein synthesis by Gq protein-coupled receptor agonists in adult cardiomyocytes.
Journal: Circulation research 20021101
Title: Regulation of uncoupling protein-2 mRNA in L6 myotubules: I: Thiazolidinediones stimulate uncoupling protein-2 gene expression by a mechanism requiring ongoing protein synthesis and an active mitogen-activated protein kinase.
Journal: Endocrine 20021101
Title: Evidence that the dephosphorylation of Ser(535) in the epsilon-subunit of eukaryotic initiation factor (eIF) 2B is insufficient for the activation of eIF2B by insulin.
Journal: The Biochemical journal 20021015
Title: Estrogen receptor alpha-mediated silencing of caveolin gene expression in neuronal cells.
Journal: The Journal of biological chemistry 20021011
Title: Regulation of lipoprotein lipase by protein kinase C alpha in 3T3-F442A adipocytes.
Journal: The Journal of biological chemistry 20021011
Title: IL-6 mediated activation of STAT3 bypasses Janus kinases in terminally differentiated B lineage cells.
Journal: Oncogene 20021003
Title: Proliferation of IL-6-independent multiple myeloma does not require the activity of extracellular signal-regulated kinases (ERK1/2).
Journal: Journal of cellular physiology 20021001
Title: Tumor necrosis factor-alpha stimulates lipolysis in differentiated human adipocytes through activation of extracellular signal-related kinase and elevation of intracellular cAMP.
Journal: Diabetes 20021001
Title: Phosphatidylinositol 3'-kinase and MAPK/ERK kinase 1/2 differentially regulate expression of vascular endothelial growth factor in human malignant astrocytoma cells.
Journal: Neuro-oncology 20021001
Title: Cerulein-induced acute pancreatitis in the rat is significantly ameliorated by treatment with MEK1/2 inhibitors U0126 and PD98059.
Journal: Pancreas 20021001
Title: Activation of proteinase-activated receptor 1 stimulates epithelial chloride secretion through a unique MAP kinase- and cyclo-oxygenase-dependent pathway.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20021001
Title: Early activation of the p42/p44MAPK pathway mediates adenosine-induced nitric oxide production in human endothelial cells: a novel calcium-insensitive mechanism.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20021001
Title: The transcript-level-independent activation of ornithine decarboxylase in suspension-cultured BY2 cells entering the cell cycle.
Journal: Plant & cell physiology 20021001
Title: Plasticity of pheochromocytoma cell lines from neurofibromatosis knockout mice.
Journal: Annals of the New York Academy of Sciences 20021001
Title: Regulation of catecholamine synthesis by leptin.
Journal: Annals of the New York Academy of Sciences 20021001
Title: Fibroblast growth factor 2 induction of the osteocalcin gene requires MAPK activity and phosphorylation of the osteoblast transcription factor, Cbfa1/Runx2.
Journal: The Journal of biological chemistry 20020927
Title: Activation of Go-coupled dopamine D2 receptors inhibits ERK1/ERK2 in pituitary cells. A key step in the transcriptional suppression of the prolactin gene.
Journal: The Journal of biological chemistry 20020927
Title: Activations of ERK1/2 and JNK by transforming growth factor beta negatively regulate Smad3-induced alkaline phosphatase activity and mineralization in mouse osteoblastic cells.
Journal: The Journal of biological chemistry 20020927
Title: Sustained activation of MEK1-ERK1/2 pathway in membrane skeleton occurs dependently on cell adhesion in megakaryocytic differentiation.
Journal: Biochemical and biophysical research communications 20020927
Title: KN-62 enhances Chlamydia pneumoniae-induced p44/p42 mitogen-activated protein kinase activation in murine fibroblasts and attenuates in vitro infection.
Journal: FEMS microbiology letters 20020924
Title: Angiogenesis-independent cardioprotection in FGF-1 transgenic mice.
Journal: Cardiovascular research 20020901
Title: Phosphorylation of extracellular signal-regulated kinase in primary afferent neurons by noxious stimuli and its involvement in peripheral sensitization.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020901
Title: Caspase inhibitors induce a switch from apoptotic to proinflammatory signaling in CD95-stimulated T lymphocytes.
Journal: European journal of immunology 20020901
Title: Constitutive active p21ras enhances primary T cell responsiveness to Ca2+ signals without interfering with the induction of clonal anergy.
Journal: European journal of immunology 20020901
Title: Activation of mitogen-activated protein kinases (MAPKs) by aromatic hydrocarbons: role in the regulation of aryl hydrocarbon receptor (AHR) function.
Journal: Biochemical pharmacology 20020901
Title: Regulation of ionomycin-mediated granule release from rat basophil leukemia cells.
Journal: Molecular immunology 20020901
Title: Induction of fetal hemoglobin synthesis by valproate: modulation of MAP kinase pathways.
Journal: American journal of hematology 20020901
Title: Activation of phosphatidylinositol 3-kinase is important for erythropoietin-induced erythropoiesis from CD34(+) hematopoietic progenitor cells.
Journal: Experimental hematology 20020901
Title: Transcription inhibitor actinomycin-D abolishes the cardioprotective effect of ischemic reconditioning.
Journal: Cardiovascular research 20020815
Title: Evidence that inhibition of p44/42 mitogen-activated protein kinase signaling is a factor in proteasome inhibitor-mediated apoptosis.
Journal: The Journal of biological chemistry 20020802
Title: A mitogen-activated protein kinase is involved in the inotropic but not chronotropic actions of adrenoceptor agonists and endothelin-1.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20020801
Title: Suppression of urokinase receptor expression by bikunin is associated with inhibition of upstream targets of extracellular signal-regulated kinase-dependent cascade.
Journal: European journal of biochemistry 20020801
Title: MEK inhibitor U0126 interferes with immunofluorescence analysis of apoptotic cell death.
Journal: Cytometry 20020801
Title: MEK mediates v-Src-induced disruption of the actin cytoskeleton via inactivation of the Rho-ROCK-LIM kinase pathway.
Journal: The Journal of biological chemistry 20020726
Title: Indomethacin causes prostaglandin D(2)-like and eotaxin-like selective responses in eosinophils and basophils.
Journal: The Journal of biological chemistry 20020719
Title: A novel pathway for nickel-induced interleukin-8 expression.
Journal: The Journal of biological chemistry 20020705
Title: Pyridinylimidazole p38 mitogen-activated protein kinase inhibitors block intracellular Toxoplasma gondii replication.
Journal: International journal for parasitology 20020701
Title: Interleukin-1beta elevates cyclooxygenase-2 protein level and enzyme activity via increasing its mRNA stability in human endometrial stromal cells: an effect mediated by extracellularly regulated kinases 1 and 2.
Journal: The Journal of clinical endocrinology and metabolism 20020701
Title: Inactivation of the antiapoptotic phosphatidylinositol 3-kinase-Akt pathway by the combined treatment of taxol and mitogen-activated protein kinase kinase inhibition.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20020701
Title: NO attenuates insulin signaling and motility in aortic smooth muscle cells via protein tyrosine phosphatase 1B-mediated mechanism.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20020701
Title: Mechanisms involved in responses to the poroxisome proliferator WY-14,643 on gap junctional intercellular communication in V79 hamster fibroblasts.
Journal: Toxicology and applied pharmacology 20020701
Title: Ligand-independent activation of steroid receptors.
Journal: Domestic animal endocrinology 20020701
Title: ERK activation and nuclear translocation in amyloid-beta peptide- and iron-stressed neuronal cell cultures.
Journal: The European journal of neuroscience 20020701
Title: Activation of the ERK pathway and atypical protein kinase C isoforms in exercise- and aminoimidazole-4-carboxamide-1-beta-D-riboside (AICAR)-stimulated glucose transport.
Journal: The Journal of biological chemistry 20020628
Title: c-Raf/MEK/ERK pathway controls protein kinase C-mediated p70S6K activation in adult cardiac muscle cells.
Journal: The Journal of biological chemistry 20020621
Title: Activation of Erk1/2 and Akt in astrocytes under ischemia.
Journal: Biochemical and biophysical research communications 20020614
Title: Distinct mechanisms of taxol-induced serine phosphorylation of the 66-kDa Shc isoform in A549 and RAW 264.7 cells.
Journal: Biochimica et biophysica acta 20020612
Title: Membrane lipids, EGF receptors, and intracellular signals colocalize and are polarized in epithelial cells moving directionally in a physiological electric field.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020601
Title: IL-17 stimulates inflammatory responses via NF-kappaB and MAP kinase pathways in human colonic myofibroblasts.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20020601
Title: Mitogen-activated protein kinase activity in cumulus cells is essential for gonadotropin-induced oocyte meiotic resumption and cumulus expansion in the mouse.
Journal: Endocrinology 20020601
Title: Proteasome inhibitor MG-132 enhances the expression of interleukin-6 in human umbilical vein endothelial cells: Involvement of MAP/ERK kinase.
Journal: Immunology and cell biology 20020601
Title: Skewed differentiation of thymocytes toward CD8 T cells by 2,3,7,8-tetrachlorodibenzo- p-dioxin requires activation of the extracellular signal-related kinase pathway.
Journal: Archives of toxicology 20020601
Title: alpha 2B-adrenergic receptor activates MAPK via a pathway involving arachidonic acid metabolism, matrix metalloproteinases, and epidermal growth factor receptor transactivation.
Journal: The Journal of biological chemistry 20020531
Title: ERK negatively regulates the epidermal growth factor-mediated interaction of Gab1 and the phosphatidylinositol 3-kinase.
Journal: The Journal of biological chemistry 20020531
Title: The MEK/ERK pathway mediates COX-2-selective NSAID-induced apoptosis and induced COX-2 protein expression in colorectal carcinoma cells.
Journal: International journal of cancer 20020520
Title: Ubiquitin (UbC) expression in muscle cells is increased by glucocorticoids through a mechanism involving Sp1 and MEK1.
Journal: The Journal of biological chemistry 20020510
Title: ERK8, a new member of the mitogen-activated protein kinase family.
Journal: The Journal of biological chemistry 20020510
Title: The phosphatidylinositol 3-kinase (PI3K)-Akt pathway suppresses Bax translocation to mitochondria.
Journal: The Journal of biological chemistry 20020419
Title: Intracellular calcium mobilization induces period genes via MAP kinase pathways in NIH3T3 cells.
Journal: FEBS letters 20020410
Title: Requirement for a hsp90 chaperone-dependent MEK1/2-ERK pathway for B cell antigen receptor-induced cyclin D2 expression in mature B lymphocytes.
Journal: The Journal of biological chemistry 20020405
Title: Cadmium-induced DNA synthesis and cell proliferation in macrophages: the role of intracellular calcium and signal transduction mechanisms.
Journal: Cellular signalling 20020401
Title: Regulation of IL-13 synthesis in human lymphocytes: implications for asthma therapy.
Journal: British journal of pharmacology 20020401
Title: Importance of MEK-1/-2 signaling in monocytic and granulocytic differentiation of myeloid cell lines.
Journal: Leukemia 20020401
Title: Hepatocyte growth factor induces ERK-dependent paxillin phosphorylation and regulates paxillin-focal adhesion kinase association.
Journal: The Journal of biological chemistry 20020322
Title: Hydrogen peroxide stimulates c-Src-mediated big mitogen-activated protein kinase 1 (BMK1) and the MEF2C signaling pathway in PC12 cells: potential role in cell survival following oxidative insults.
Journal: The Journal of biological chemistry 20020315
Title: Distinct region of the granulocyte colony-stimulating factor receptor mediates proliferative signaling through activation of Janus kinase 2 and p44/42 mitogen-activated protein kinase.
Journal: Cellular signalling 20020301
Title: Inorganic lead activates the mitogen-activated protein kinase kinase-mitogen-activated protein kinase-p90(RSK) signaling pathway in human astrocytoma cells via a protein kinase C-dependent mechanism.
Journal: The Journal of pharmacology and experimental therapeutics 20020301
Title: Mitogen-activated protein/extracellular signal-regulated kinase kinase (MEK) inhibitors restore anoikis sensitivity in human breast cancer cell lines with a constitutively activated extracellular-regulated kinase (ERK) pathway.
Journal: Molecular cancer therapeutics 20020301
Title: Insulin stimulates nitric oxide production in rat adipocytes.
Journal: Biochemical and biophysical research communications 20020222
Title: Inhibitors of farnesyl protein transferase and MEK1,2 induce apoptosis in fibroblasts transformed with farnesylated but not geranylgeranylated H-Ras.
Journal: Experimental cell research 20020215
Title: Retinoic acid activation of the ERK pathway is required for embryonic stem cell commitment into the adipocyte lineage.
Journal: The Biochemical journal 20020201
Title: Mechanism of prostaglandin E2-stimulated heat shock protein 27 induction in osteoblast-like MC3T3-E1 cells.
Journal: The Journal of endocrinology 20020201
Title: Mitogen-activated protein kinase kinase negatively modulates ciliary neurotrophic factor-activated choline acetyltransferase gene expression.
Journal: European journal of biochemistry 20020201
Title: The effects of laminin-1 on spiral ganglion neurons are dependent on the MEK/ERK signaling pathway and are partially independent of Ras.
Journal: Hearing research 20020201
Title: Anchorage-independent multi-cellular spheroids as an in vitro model of growth signaling in Ewing tumors.
Journal: Oncogene 20020110
Title: Non-specific effects of the MEK inhibitors PD098,059 and U0126 on glutamate release from hippocampal synaptosomes.
Journal: Neuropharmacology 20020101
Title: Association between alphavbeta6 integrin expression, elevated p42/44 kDa MAPK, and plasminogen-dependent matrix degradation in ovarian cancer.
Journal: Journal of cellular biochemistry 20020101
Title: Inhibition of the MEK1/ERK pathway reduces arachidonic acid release independently of cPLA2 phosphorylation and translocation.
Journal: BMC biochemistry 20020101
Title: Coadministration of UCN-01 with MEK1/2 inhibitors potently induces apoptosis in BCR/ABL+ leukemia cells sensitive and resistant to ST1571.
Journal: Cancer biology & therapy 20020101
Title: The induction of cyclooxygenase-2 mRNA in macrophages is biphasic and requires both CCAAT enhancer-binding protein beta (C/EBP beta ) and C/EBP delta transcription factors.
Journal: The Journal of biological chemistry 20011228
Title: 15-Deoxy-delta 12,14-prostaglandin J2 and thiazolidinediones activate the MEK/ERK pathway through phosphatidylinositol 3-kinase in vascular smooth muscle cells.
Journal: The Journal of biological chemistry 20011228
Title: Role of ERK1/2 in the differential synthesis of progesterone and estradiol by granulosa cells.
Journal: Biochemical and biophysical research communications 20011214
Title: Transcriptional induction of MKP-1 in response to stress is associated with histone H3 phosphorylation-acetylation.
Journal: Molecular and cellular biology 20011201
Title: Neurotrophin-3 inhibits HCO absorption via a cAMP-dependent pathway in renal thick ascending limb.
Journal: American journal of physiology. Cell physiology 20011201
Title: Enhancement of survival by LPA via Erk1/Erk2 and PI 3-kinase/Akt pathways in a murine hepatocyte cell line.
Journal: American journal of physiology. Cell physiology 20011201
Title: Mechanisms of cytokine effects on G protein-coupled receptor-mediated signaling in airway smooth muscle.
Journal: American journal of physiology. Lung cellular and molecular physiology 20011201
Title: Differential regulation of diverse physiological responses to VEGF in pulmonary endothelial cells.
Journal: American journal of physiology. Lung cellular and molecular physiology 20011201
Title: Stimulation of extracellular signal-regulated kinase by pituitary adenylate cyclase-activating polypeptide in alpha T3-1 gonadotrophs.
Journal: The Journal of endocrinology 20011201
Title: Angiotensin II promotes the phosphorylation of cyclic AMP-responsive element binding protein (CREB) at Ser133 through an ERK1/2-dependent mechanism.
Journal: Journal of neurochemistry 20011201
Title: Tissue inhibitor of metalloproteinases 1 and 2 directly stimulate the bone-resorbing activity of isolated mature osteoclasts.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20011201
Title: Ras/MEK but not p38 signaling mediates NT-3-induced neurite extension from spiral ganglion neurons.
Journal: Journal of the Association for Research in Otolaryngology : JARO 20011201
Title: alpha-Synuclein affects the MAPK pathway and accelerates cell death.
Journal: The Journal of biological chemistry 20011130
Title: Alternate FGF2-ERK1/2 signaling pathways in retinal photoreceptor and glial cells in vitro.
Journal: The Journal of biological chemistry 20011123
Title: Potentiation of cadmium-induced cytotoxicity by sulfur amino acid deprivation through activation of extracellular signal-regulated kinase1/2 (ERK1/2) in conjunction with p38 kinase or c-jun N-terminal kinase (JNK). Complete inhibition of the potentiated toxicity by U0126 an ERK1/2 and p38 kinase inhibitor.
Journal: Biochemical pharmacology 20011115
Title: Ceramide inhibits the inwardly rectifying potassium current in GH(3) lactotrophs.
Journal: Endocrinology 20011101
Title: Inhibition of PKA blocks fibroblast migration in response to growth factors.
Journal: Experimental cell research 20011101
Title: A role for mitogen-activated protein kinases in the etiology of diabetic neuropathy.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20011101
Title: Activation of extracellular signal-regulated kinases potentiates hemin toxicity in astrocyte cultures.
Journal: Journal of neurochemistry 20011101
Title: Neuroprotective effect of sodium orthovanadate on delayed neuronal death after transient forebrain ischemia in gerbil hippocampus.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20011101
Title: Differential activation of ERKs to focal adhesions by PKC epsilon is required for PMA-induced adhesion and migration of human glioma cells.
Journal: Oncogene 20011101
Title: Bleomycin upregulates gene expression of angiotensin-converting enzyme via mitogen-activated protein kinase and early growth response 1 transcription factor.
Journal: American journal of respiratory cell and molecular biology 20011101
Title: Cytotoxicity induced by manipulation of signal transduction pathways is associated with down-regulation of Bcl-2 but not Mcl-1 in MCF-7 human breast cancer.
Journal: Breast cancer research and treatment 20011101
Title: Angiotensin II-induced transcriptional activation of the cyclin D1 gene is mediated by Egr-1 in CHO-AT(1A) cells.
Journal: The Journal of biological chemistry 20011019
Title: Induction of the IL-13 receptor alpha2-chain by IL-4 and IL-13 in human keratinocytes: involvement of STAT6, ERK and p38 MAPK pathways.
Journal: Oncogene 20011011
Title: Effects of Ginkgo biloba extract (EGb 761) and quercetin on lipopolysaccharide-induced signaling pathways involved in the release of tumor necrosis factor-alpha.
Journal: Biochemical pharmacology 20011001
Title: Antidepressant drug treatments induce glial cell line-derived neurotrophic factor (GDNF) synthesis and release in rat C6 glioblastoma cells.
Journal: Journal of neurochemistry 20011001
Title: The mechanism of cell cycle regulation by v-Src.
Journal: Oncogene 20010920
Title: Inhibition of the ERK pathway prevents HIVgp120-induced REM sleep increase.
Journal: Brain research 20010914
Title: Suppression of cell spreading by v-Crk requires Ras-MEK-MAP kinase signaling.
Journal: Oncogene 20010913
Title: MEK1/2 inhibitors promote Ara-C-induced apoptosis but not loss of Deltapsi(m) in HL-60 cells.
Journal: Biochemical and biophysical research communications 20010907
Title: Activation of p44/p42 mitogen-activated protein kinase limits triiodothyronine-stimulated alkaline phosphatase activity in osteoblasts.
Journal: Biochemical and biophysical research communications 20010907
Title: Cytosolic phospholipase A(2) activity during the ongoing cell cycle.
Journal: Journal of cellular physiology 20010901
Title: Nickel requires hypoxia-inducible factor-1 alpha, not redox signaling, to induce plasminogen activator inhibitor-1.
Journal: American journal of physiology. Lung cellular and molecular physiology 20010901
Title: Early growth-responsive-1-dependent manganese superoxide dismutase gene transcription mediated by platelet-derived growth factor.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010901
Title: C1q-bearing immune complexes induce IL-8 secretion in human umbilical vein endothelial cells (HUVEC) through protein tyrosine kinase- and mitogen-activated protein kinase-dependent mechanisms: evidence that the 126 kD phagocytic C1q receptor mediates immune complex activation of HUVEC.
Journal: Clinical and experimental immunology 20010901
Title: Endogenous angiotensin II suppresses insulin signaling in vascular smooth muscle cells from spontaneously hypertensive rats.
Journal: Journal of hypertension 20010901
Title: Regeneration in avian hair cell epithelia: identification of intracellular signals required for S-phase entry.
Journal: The European journal of neuroscience 20010901
Title: Cross-talk between the ERK and p70 S6 kinase (S6K) signaling pathways. MEK-dependent activation of S6K2 in cardiomyocytes.
Journal: The Journal of biological chemistry 20010831
Title: ERK regulates the hepatocyte growth factor-mediated interaction of Gab1 and the phosphatidylinositol 3-kinase.
Journal: The Journal of biological chemistry 20010831
Title: Keratinocyte growth factor activates p38 MAPK to induce stress fibre formation in human prostate DU145 cells.
Journal: Oncogene 20010830
Title: Phosphorylation of raf-1 by kinase suppressor of ras is inhibited by 'MEK-specific' inhibitors PD 098059 and U0126 in differentiating HL60 cells.
Journal: Experimental cell research 20010815
Title: Inhibitors of mitogen-activated protein kinases differentially regulate eosinophil-activating cytokine release from human airway smooth muscle.
Journal: American journal of respiratory and critical care medicine 20010815
Title: Chlamydia pneumoniae and chlamydial heat shock protein 60 stimulate proliferation of human vascular smooth muscle cells via toll-like receptor 4 and p44/p42 mitogen-activated protein kinase activation.
Journal: Circulation research 20010803
Title: Protection against glutamate toxicity through inhibition of the p44/42 mitogen-activated protein kinase pathway in neuronally differentiated P19 cells.
Journal: Biochemical pharmacology 20010801
Title: Insulin-independent, MAPK-dependent stimulation of NKCC activity in skeletal muscle.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20010801
Title: Activation of Akt1 by human 5-hydroxytryptamine (serotonin)1B receptors is sensitive to inhibitors of MEK.
Journal: The Journal of pharmacology and experimental therapeutics 20010801
Title: Selective potentiation of paclitaxel (taxol)-induced cell death by mitogen-activated protein kinase kinase inhibition in human cancer cell lines.
Journal: Molecular pharmacology 20010801
Title: Calcium-mediated inactivation of the MAP kinase pathway in sea urchin eggs at fertilization.
Journal: Developmental biology 20010801
Title: Inhibition of phosphatidylinositol 3-kinase or mitogen-activated protein kinase kinase leads to suppression of p34(cdc2) kinase activity and meiotic progression beyond the meiosis I stage in porcine oocytes surrounded with cumulus cells.
Journal: Biology of reproduction 20010801
Title: Tyrosine hydroxylase phosphorylation in bovine adrenal chromaffin cells: the role of MAPKs after angiotensin II stimulation.
Journal: Journal of neurochemistry 20010801
Title: Calcium and pituitary adenylate cyclase-activating polypeptide induced expression of circadian clock gene mPer1 in the mouse cerebellar granule cell culture.
Journal: Journal of neurochemistry 20010801
Title: Requirement for sustained MAPK signaling in both CD4 and CD8 lineage commitment: a threshold model.
Journal: Cellular immunology 20010801
Title: Arylhydrocarbon receptor (AhR) is involved in negative regulation of adipose differentiation in 3T3-L1 cells: AhR inhibits adipose differentiation independently of dioxin.
Journal: Journal of cell science 20010801
Title: Effects of MAP kinase cascade inhibitors on the MKK5/ERK5 pathway.
Journal: FEBS letters 20010727
Title: Polyamines regulate gap junction communication in connexin 43-expressing cells.
Journal: The Biochemical journal 20010715
Title: HGF promotes adhesion of ATP-depleted renal tubular epithelial cells in a MAPK-dependent manner.
Journal: American journal of physiology. Renal physiology 20010701
Title: Involvement of the MAP kinase ERK2 in MUC1 mucin signaling.
Journal: American journal of physiology. Lung cellular and molecular physiology 20010701
Title: Activation of extracellular signal-regulated kinase in trabecular meshwork cells.
Journal: Experimental eye research 20010701
Title: Activation of p38, ERK1/2 and NIK pathways is required for IL-1beta and TNF-alpha-induced chemokine expression in human retinal pigment epithelial cells.
Journal: Experimental eye research 20010701
Title: Pharmacological inhibitors of the mitogen-activated protein kinase (MAPK) kinase/MAPK cascade interact synergistically with UCN-01 to induce mitochondrial dysfunction and apoptosis in human leukemia cells.
Journal: Cancer research 20010701
Title: Transforming growth factor-beta induces osteoclast ruffling and chemotaxis: potential role in osteoclast recruitment.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20010701
Title: Role of the extracellular signal-regulated kinase (Erk) signal transduction cascade in alpha(2) adrenoceptor-mediated vasoconstriction in porcine palmar lateral vein.
Journal: British journal of pharmacology 20010701
Title: Extracellular-regulated kinase controls beta-amyloid precursor protein mRNA decay.
Journal: Brain research. Molecular brain research 20010620
Title: Autoregulation of cell-specific MAP kinase control of the tryptophan hydroxylase promoter.
Journal: The Journal of biological chemistry 20010615
Title: ERK7 is an autoactivated member of the MAPK family.
Journal: The Journal of biological chemistry 20010615
Title: Spatial analysis of key signaling proteins by high-content solid-phase cytometry in Hep3B cells treated with an inhibitor of Cdc25 dual-specificity phosphatases.
Journal: The Journal of biological chemistry 20010608
Title: Mechanical strain and estrogen activate estrogen receptor alpha in bone cells.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20010601
Title: Robust expression of TNF-alpha, IL-1beta, RANTES, and IP-10 by human microglial cells during nonproductive infection with herpes simplex virus.
Journal: Journal of neurovirology 20010601
Title: Role of the ERK pathway in the activation of store-mediated calcium entry in human platelets.
Journal: The Journal of biological chemistry 20010511
Title: Inhibition of phosphatidylinositol-3 kinase/Akt or mitogen-activated protein kinase signaling sensitizes endothelial cells to TNF-alpha cytotoxicity.
Journal: Cell death and differentiation 20010501
Title: Transcriptional cross-talk between Smad, ERK1/2, and p38 mitogen-activated protein kinase pathways regulates transforming growth factor-beta-induced aggrecan gene expression in chondrogenic ATDC5 cells.
Journal: The Journal of biological chemistry 20010427
Title: Manganese superoxide dismutase signals matrix metalloproteinase expression via H2O2-dependent ERK1/2 activation.
Journal: The Journal of biological chemistry 20010427
Title: Measurement of MAP kinase activation by flow cytometry using phospho-specific antibodies to MEK and ERK: potential for pharmacodynamic monitoring of signal transduction inhibitors.
Journal: Cytometry 20010415
Title: Dynamic changes of connexin-43, gap junctional protein, in outer layers of cumulus cells are regulated by PKC and PI 3-kinase during meiotic resumption in porcine oocytes.
Journal: Biology of reproduction 20010401
Title: Role of ERK activation in growth and erythroid differentiation of K562 cells.
Journal: Experimental cell research 20010401
Title: Synergistic induction of apoptosis in human leukemia cells (U937) exposed to bryostatin 1 and the proteasome inhibitor lactacystin involves dysregulation of the PKC/MAPK cascade.
Journal: Blood 20010401
Title: Signal transduction pathways for activation of extracellular signal-regulated kinase by arachidonic acid in rat neutrophils.
Journal: Journal of leukocyte biology 20010401
Title: Grb-2-associated binder-1 is involved in insulin-induced egr-1 gene expression through its phosphatidylinositol 3'-kinase binding site.
Journal: DNA and cell biology 20010401
Title: Ribosomal S6 kinase 2 inhibition by a potent C-terminal repressor domain is relieved by mitogen-activated protein-extracellular signal-regulated kinase kinase-regulated phosphorylation.
Journal: The Journal of biological chemistry 20010316
Title: Differential roles of the NPXXY motif in formyl peptide receptor signaling.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20010315
Title: Involvement of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase in alpha1B-adrenergic receptor/Galphaq-induced inhibition of cell proliferation.
Journal: Biochemical and biophysical research communications 20010309
Title: Polo-like kinase 1 phosphorylates cyclin B1 and targets it to the nucleus during prophase.
Journal: Nature 20010308
Title: Involvement of extracellular signal-regulated kinase (ERK) in pardaxin-induced dopamine release from PC12 cells.
Journal: The Journal of pharmacology and experimental therapeutics 20010301
Title: Extracellular signal-regulated kinase 1/2-mediated phosphorylation of cytosolic phospholipase A2 is essential for human eosinophil adhesion to fibronectin.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20010301
Title: Inhibition of extracellular signal-regulated kinase 1/2 phosphorylation and induction of apoptosis by sulindac metabolites.
Journal: Cancer research 20010215
Title: Lipid constituents in oligodendroglial cells alter susceptibility to H2O2-induced apoptotic cell death via ERK activation.
Journal: Journal of neurochemistry 20010201
Title: Stimulation of catecholamine synthesis in cultured bovine adrenal medullary cells by leptin.
Journal: Journal of neurochemistry 20010201
Title: Neuroprotection by estrogen via extracellular signal-regulated kinase against quinolinic acid-induced cell death in the rat hippocampus.
Journal: The European journal of neuroscience 20010201
Title: c-Jun N-terminal kinase activation in Xenopus laevis eggs and embryos. A possible non-genomic role for the JNK signaling pathway.
Journal: The Journal of biological chemistry 20010112
Title: Signaling pathways leading to the induction of ornithine decarboxylase: opposite effects of p44/42 mitogen-activated protein kinase (MAPK) and p38 MAPK inhibitors.
Journal: Biochemical pharmacology 20010101
Title: Protein kinase inhibitors can suppress stress-induced dissociation of Hsp27.
Journal: Cell stress & chaperones 20010101
Title: Requirement for ERK activation in cisplatin-induced apoptosis.
Journal: The Journal of biological chemistry 20001215
Title: Specificity and mechanism of action of some commonly used protein kinase inhibitors.
Journal: The Biochemical journal 20001001
Title: Residual type 1 immunity in patients genetically deficient for interleukin 12 receptor beta1 (IL-12Rbeta1): evidence for an IL-12Rbeta1-independent pathway of IL-12 responsiveness in human T cells.
Journal: The Journal of experimental medicine 20000821
Title: 5-lipoxygenase is phosphorylated by p38 kinase-dependent MAPKAP kinases.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20000509
Title: Method for preservation of water content during prolonged storage of cerebral tissue.
Journal: Neurological research 19900301
Title: Glucocorticoid prevents brain-derived neurotrophic factor-mediated maturation of synaptic function in developing hippocampal neurons through reduction in the activity of mitogen-activated protein kinase.
Journal: Molecular endocrinology (Baltimore, Md.)
