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109889-09-0,MFCD00865550
Catalog No.:AA007EFL

109889-09-0 | Granisetron

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
≥98.0%
in stock  
$181.00   $127.00
- +
25mg
≥98.0%
in stock  
$488.00   $342.00
- +
100mg
≥98.0%
in stock  
$1,284.00   $899.00
- +
250mg
≥98.0%
in stock  
$2,204.00   $1,543.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA007EFL
Chemical Name:
Granisetron
CAS Number:
109889-09-0
Molecular Formula:
C18H24N4O
Molecular Weight:
312.4094
MDL Number:
MFCD00865550
SMILES:
CN1C2CCCC1CC(C2)NC(=O)c1nn(c2c1cccc2)C
Properties
Computed Properties
 
Complexity:
442  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
XLogP3:
2.8  

Literature

Title: Sanger GJ, Nelson DR. Selective and functional 5-hydroxytryptamine3 receptor antagonism by BRL 43694 (granisetron). Eur J Pharmacol. 1989 Jan 10;159(2):113-24.

Title: Maleki-Dizaji N, Eteraf-Oskouei T, Fakhrjou A, The effects of 5HT3 receptor antagonist granisetron on inflammatory parameters and angiogenesis in the air-pouch model of inflammation. Int Immunopharmacol. 2010 Sep;10(9):1010-6.

Title: Boccia RV, Gordan LN, Clark G, Efficacy and tolerability of transdermal granisetron for the control of chemotherapy-induced nausea and vomiting associated with moderately and highly emetogenic multi-day chemotherapy: a randomized, double-blind, phase III study. Support Care Cancer. 2011 Oct;19(10):1609-17.

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SDS
Tags:109889-09-0 Molecular Formula|109889-09-0 MDL|109889-09-0 SMILES|109889-09-0 Granisetron