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11021-13-9,MFCD00221755
Catalog No.:AA008R0T

11021-13-9 | GINSENOSIDE RB2

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1mg
95%
in stock  
$86.00   $60.00
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5mg
≥98%
in stock  
$133.00   $93.00
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10mg
≥98%
in stock  
$252.00   $176.00
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20mg
in stock  
$415.00   $290.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA008R0T
Chemical Name:
GINSENOSIDE RB2
CAS Number:
11021-13-9
Molecular Formula:
C53H90O22
Molecular Weight:
1079.2685
MDL Number:
MFCD00221755
SMILES:
OC[C@H]1O[C@@H](O[C@H]2CC[C@]3([C@H](C2(C)C)CC[C@@]2([C@@H]3C[C@@H](O)[C@H]3[C@@]2(C)CC[C@@H]3[C@@](O[C@@H]2O[C@H](CO[C@@H]3OC[C@@H]([C@@H]([C@H]3O)O)O)[C@H]([C@@H]([C@H]2O)O)O)(CCC=C(C)C)C)C)C)[C@@H]([C@H]([C@@H]1O)O)O[C@@H]1O[C@H](CO)[C@H]([C@@H]([C@H]1O)O)O
Properties
Computed Properties
 
Complexity:
1950  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
29  
Heavy Atom Count:
75  
Hydrogen Bond Acceptor Count:
22  
Hydrogen Bond Donor Count:
14  
Rotatable Bond Count:
15  
XLogP3:
0.3  

Literature

Title: Effects of ginsenosides on the expression of cytochrome P450s and transporters involved in cholesterol metabolism.

Journal: Journal of natural medicines 20140401

Title: Enzymatic transformation of the major ginsenoside Rb2 to minor compound Y and compound K by a ginsenoside-hydrolyzing β-glycosidase from Microbacterium esteraromaticum.

Journal: Journal of industrial microbiology & biotechnology 20121001

Title: Determination of ginsenosides Rb1, Rb2, and Rb3 in rat plasma by a rapid and sensitive liquid chromatography tandem mass spectrometry method: Application in a pharmacokinetic study.

Journal: Journal of pharmaceutical and biomedical analysis 20120501

Title: Antioxidant, antiproliferative, and pro-apoptotic activities of a saponin extract derived from the roots of Panax notoginseng (Burk.) F.H. Chen.

Journal: Journal of medicinal food 20120401

Title: AMP-activated protein kinase: a potential target for ginsenosides?

Journal: Archives of pharmacal research 20110701

Title: The antidiabetic effect of ginsenoside Rb2 via activation of AMPK.

Journal: Archives of pharmacal research 20110701

Title: [Absorption characteristics of ginsenoside Rb2 in Caco-2 cell monolayer].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20091201

Title: The ginsenoside-Rb2 lowers cholesterol and triacylglycerol levels in 3T3-L1 adipocytes cultured under high cholesterol or fatty acids conditions.

Journal: BMB reports 20090430

Title: [A quantitative method using one marker for simultaneous assay of ginsenosides in Panax ginseng and P. notoginseng].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20081201

Title: Method development for gypenosides fingerprint by high performance liquid chromatography with diode-array detection and the addition of internal standard.

Journal: Chemical & pharmaceutical bulletin 20080301

Title: Study on the noncovalent complexes of ginsenoside and cytochrome c by electrospray ionization mass spectrometry.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20071001

Title: Study on the hydroxyl radical scavenging activity changes of ginseng and ginsenoside-Rb2 by heat processing.

Journal: Biological & pharmaceutical bulletin 20070401

Title: Purification and characterization of new special ginsenosidase hydrolyzing multi-glycisides of protopanaxadiol ginsenosides, ginsenosidase type I.

Journal: Chemical & pharmaceutical bulletin 20070201

Title: A ginsenoside metabolite, 20-O-beta-D-glucopyranosyl-20(S)-protopanaxadiol, triggers apoptosis in activated rat hepatic stellate cells via caspase-3 activation.

Journal: Planta medica 20061001

Title: Transformation of ginsenosides Rb2 and Rc from Panax ginseng by food microorganisms.

Journal: Biological & pharmaceutical bulletin 20051101

Title: Simultaneous determination of ginsenoside Rb(1) and Rg(1) in human plasma by liquid chromatography-mass spectrometry.

Journal: Journal of pharmaceutical and biomedical analysis 20040401

Title: Enhancement of fibrinolytic activity of bovine aortic endothelial cells by ginsenoside Rb2.

Journal: Acta pharmacologica Sinica 20030201

Title: Ginsenosides from Panax ginseng differentially regulate lymphocyte proliferation.

Journal: Planta medica 20020601

Title: Epidermis proliferative effect of the Panax ginseng ginsenoside Rb2.

Journal: Archives of pharmacal research 20020201

Title: Triterpene saponins from Vietnamese ginseng (Panax vietnamensis) and their hepatocytoprotective activity.

Journal: Journal of natural products 20010401

Title: In vitro inhibitory effect of protopanaxadiol ginsenosides on tumor necrosis factor (TNF)-alpha production and its modulation by known TNF-alpha antagonists.

Journal: Planta medica 20010401

Title: Effects of Ginsenoside Rb2 and Rc on inferior human sperm motility in vitro.

Journal: The American journal of Chinese medicine 20010101

Title: Ginsenosides increase secretion of lipoprotein lipase by 3T3-L1 adipocytes.

Journal: Bioscience, biotechnology, and biochemistry 19961201

Title: Huang Q, et al. Ginsenoside Rb2 enhances the anti-inflammatory effect of ω-3 fatty acid in LPS-stimulated RAW264.7 macrophages by upregulating GPR120 expression. Acta Pharmacol Sin. 2017 Feb;38(2):192-200.

Title: Yang H, et al. Ginsenoside-Rb2and 20(S)-Ginsenoside-Rg3 from Koreanred ginseng prevent rotavirus infection in newborn mice. J Microbiol Biotechnol. 2018 Jan 11.

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Tags:11021-13-9 Molecular Formula|11021-13-9 MDL|11021-13-9 SMILES|11021-13-9 GINSENOSIDE RB2