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11021-14-0,MFCD00133368
Catalog No.:AA008R9D

11021-14-0 | Ginsenoside rc

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5mg
≥98%
in stock  
$98.00   $68.00
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10mg
≥98%
in stock  
$173.00   $121.00
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25mg
≥98%
in stock  
$383.00   $268.00
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50mg
98% by HPLC
in stock  
$622.00   $435.00
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100mg
98% by HPLC
in stock  
$1,029.00   $720.00
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500mg
98% by HPLC
in stock  
$3,179.00   $2,226.00
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1000mg
98% by HPLC
in stock  
$5,049.00   $3,534.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA008R9D
Chemical Name:
Ginsenoside rc
CAS Number:
11021-14-0
Molecular Formula:
C53H90O22
Molecular Weight:
1079.2685
MDL Number:
MFCD00133368
SMILES:
OC[C@H]1O[C@@H](O[C@H]2CC[C@]3([C@H](C2(C)C)CC[C@@]2([C@@H]3C[C@@H](O)[C@H]3[C@@]2(C)CC[C@@H]3[C@@](O[C@@H]2O[C@H](CO[C@@H]3O[C@H]([C@@H]([C@H]3O)O)CO)[C@H]([C@@H]([C@H]2O)O)O)(CCC=C(C)C)C)C)C)[C@@H]([C@H]([C@@H]1O)O)O[C@@H]1O[C@H](CO)[C@H]([C@@H]([C@H]1O)O)O
Properties
Computed Properties
 
Complexity:
1950  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
29  
Heavy Atom Count:
75  
Hydrogen Bond Acceptor Count:
22  
Hydrogen Bond Donor Count:
14  
Rotatable Bond Count:
16  
XLogP3:
0.9  

Literature

Title: Molecular mechanisms governing different pharmacokinetics of ginsenosides and potential for ginsenoside-perpetrated herb-drug interactions on OATP1B3.

Journal: British journal of pharmacology 20150201

Title: Cloning and characterization of α-L-arabinofuranosidase and bifunctional α-L-arabinopyranosidase/β-D-galactopyranosidase from Bifidobacterium longum H-1.

Journal: Journal of applied microbiology 20111101

Title: Microbial transformation of ginsenosides Rb1, Rb3 and Rc by Fusarium sacchari.

Journal: Journal of applied microbiology 20100901

Title: HPLC-based activity profiling for GABA(A) receptor modulators: a new dihydroisocoumarin from Haloxylon scoparium.

Journal: Journal of natural products 20100423

Title: Ginsenoside Rc, an active component of Panax ginseng, stimulates glucose uptake in C2C12 myotubes through an AMPK-dependent mechanism.

Journal: Journal of ethnopharmacology 20100217

Title: Effects of extrusion process variables on extractable ginsenosides in wheat-ginseng extrudates.

Journal: Journal of agricultural and food chemistry 20090325

Title: [A quantitative method using one marker for simultaneous assay of ginsenosides in Panax ginseng and P. notoginseng].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20081201

Title: Purification and characterization of new special ginsenosidase hydrolyzing multi-glycisides of protopanaxadiol ginsenosides, ginsenosidase type I.

Journal: Chemical & pharmaceutical bulletin 20070201

Title: Transformation of ginsenosides Rb2 and Rc from Panax ginseng by food microorganisms.

Journal: Biological & pharmaceutical bulletin 20051101

Title: Chromatographic resolution of glucosidic compounds, ginsenosides on polyethersulphone membrane, and its application to the quantitative immunoassay for ginseng saponins.

Journal: Glycobiology 20051001

Title: [The effect of preparation method on the quality of shen-mai injection].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050501

Title: Embryotoxicity study of ginsenoside Rc and Re in in vitro rat whole embryo culture.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20041101

Title: Determination of ginsenosides Rb1, Rc, and Re in different dosage forms of ginseng by negative ion electrospray liquid chromatography-mass spectrometry.

Journal: Journal of agricultural and food chemistry 20040811

Title: Structures of new dammarane-type Triterpene Saponins from the flower buds of Panax notoginseng and hepatoprotective effects of principal Ginseng Saponins.

Journal: Journal of natural products 20030701

Title: Modulation of G protein alpha-subunit mRNA levels in discrete rat brain regions by cerebroventricular infusion of ginsenoside Rc and Rg1.

Journal: Neurochemical research 20030501

Title: Ginsenoside Rc and Re stimulate c-fos expression in MCF-7 human breast carcinoma cells.

Journal: Archives of pharmacal research 20030101

Title: Metabolism of ginsenoside R(c) by human intestinal bacteria and its related antiallergic activity.

Journal: Biological & pharmaceutical bulletin 20020601

Title: Changes of [3H]MK-801, [3H]muscimol and [3H]flunitrazepam binding in rat brain by the prolonged ventricular infusion of ginsenoside Rc and Rg1.

Journal: Pharmacological research 20010501

Title: Triterpene saponins from Vietnamese ginseng (Panax vietnamensis) and their hepatocytoprotective activity.

Journal: Journal of natural products 20010401

Title: In vitro inhibitory effect of protopanaxadiol ginsenosides on tumor necrosis factor (TNF)-alpha production and its modulation by known TNF-alpha antagonists.

Journal: Planta medica 20010401

Title: Effects of Ginsenoside Rb2 and Rc on inferior human sperm motility in vitro.

Journal: The American journal of Chinese medicine 20010101

Title: Lee BH, et al. Effects of Ginsenoside Metabolites on GABAA Receptor-Mediated Ion Currents. J Ginseng Res. 2012 Jan;36(1):55-60.

Title: Yu T, et al. Ginsenoside Rc from Panax ginseng exerts anti-inflammatory activity by targeting TANK-bindingkinase 1/interferon regulatory factor-3 and p38/ATF-2. J Ginseng Res. 2017 Apr;41(2):127-133.

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