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11050-94-5,MFCD00043232
Catalog No.:AA008RH3

11050-94-5 | Oligomycin b

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1mg
≥85%
in stock  
$58.00   $40.00
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5mg
≥85%
in stock  
$198.00   $138.00
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10mg
≥85%
in stock  
$309.00   $216.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA008RH3
Chemical Name:
Oligomycin b
CAS Number:
11050-94-5
Molecular Formula:
C45H72O12
Molecular Weight:
805.0460
MDL Number:
MFCD00043232
SMILES:
CCC1C=CC=CCC(C)C(O)C(C)(O)C(=O)C(C)C(O)C(C)C(=O)C(C(C(C=CC(=O)OC2C(C(CC1)OC1(OC(CC(O)C)C(CC1=O)C)C2C)C)C)O)C
Properties
Computed Properties
 
Complexity:
1470  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
18  
Defined Bond Stereocenter Count:
3  
Heavy Atom Count:
57  
Hydrogen Bond Acceptor Count:
12  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
3  
XLogP3:
6.1  

Literature

Title: Refining the human iPSC-cardiomyocyte arrhythmic risk assessment model.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20131201

Title: Pharmacological profile of the selective mitochondrial F1F0 ATP hydrolase inhibitor BMS-199264 in myocardial ischemia.

Journal: Cardiovascular therapeutics 20080101

Title: Excessive ATP hydrolysis in ischemic myocardium by mitochondrial F1F0-ATPase: effect of selective pharmacological inhibition of mitochondrial ATPase hydrolase activity.

Journal: American journal of physiology. Heart and circulatory physiology 20041001

Title: Mitochondrial modulation of Ca2+ sparks and transient KCa currents in smooth muscle cells of rat cerebral arteries.

Journal: The Journal of physiology 20040501

Title: Evidence that the lichen-derived scabrosin esters target mitochondrial ATP synthase in P388D1 cells.

Journal: Toxicology and applied pharmacology 20030801

Title: [Streptomyces griseolus # 182--a novel organism producing oligomycin antibiotics. Taxonomy, fermentation, and isolation].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101

Title: [Determination of the structure of the main component of an antibiotic complex produced by Streptomyces griseolus 182].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101

Title: Inhibition of glucose transport by cyclic GMP in cardiomyocytes.

Journal: Life sciences 20010810

Title: Moerman KL, et al. Evidence that the lichen-derived scabrosin esters target mitochondrial ATP synthase in P388D1 cells. Toxicol Appl Pharmacol. 2003 Aug 1;190(3):232-40.

Title: Dame ZT, et al. Oligomycins and pamamycin homologs impair motility and induce lysis of zoospores of the grapevine downy mildew pathogen, Plasmopara viticola. FEMS Microbiol Lett. 2016 Aug;363(16).

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