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Home Other Building Blocks 1105662-87-0
1105662-87-0,MFCD13190429
Catalog No.:AA008T7Y

1105662-87-0 | 1-Boc-3-methoxycarbonylmethylene-azetidine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
250mg
98%
in stock  
$13.00   $9.00
- +
1g
95%
in stock  
$18.00   $13.00
- +
5g
95%
in stock  
$62.00   $44.00
- +
50g
97.0%
in stock  
$608.00   $425.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA008T7Y
Chemical Name:
1-Boc-3-methoxycarbonylmethylene-azetidine
CAS Number:
1105662-87-0
Molecular Formula:
C11H17NO4
Molecular Weight:
227.2570
MDL Number:
MFCD13190429
SMILES:
COC(=O)C=C1CN(C1)C(=O)OC(C)(C)C
Properties
Computed Properties
 
Complexity:
319  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
4  
Rotatable Bond Count:
4  
XLogP3:
0.5  

Downstream Synthesis Route

[1]Hamill,Rosalie;Jones,Benjamin;Pask,ChristopherM.;Sridharan,Visuvanathar[TetrahedronLetters,2019,vol.60,#16,p.1126-1129]

[2]CurrentPatentAssignee:ABBVIEINC-US2015/210720,2015,A1Locationinpatent:Paragraph0620

[3]CurrentPatentAssignee:ABBVIEINC-US9777020,2017,B2Locationinpatent:Page/Pagecolumn101;102

[4]CurrentPatentAssignee:Novartis(w/oSandoz);NOVARTISAG-WO2009/10488,2009,A1Locationinpatent:Page/Pagecolumn47

[5]LeManach,Claire;Dam,Jean;Woodland,JohnG.;Kaur,Gurminder;Khonde,LuteteP.;Brunschwig,Christel;Njoroge,Mathew;Wicht,KathrynJ.;Horatscheck,André;Paquet,Tanya;Boyle,GrantA.;Gibhard,Liezl;Taylor,Dale;Lawrence,Nina;Yeo,Tomas;Mok,Sachel;Eastman,RichardT.;Dorjsuren,Dorjbal;Talley,DanielC.;Guo,Hui;Simeonov,Anton;Reader,Janette;VanDerWatt,Mariëtte;Erlank,Erica;Venter,Nelius;Zawada,JacekW.;Aswat,Ayesha;Nardini,Luisa;Coetzer,TheresaL.;Lauterbach,SonjaB.;Bezuidenhout,BelindaC.;Theron,Anjo;Mancama,Dalu;Koekemoer,LizetteL.;Birkholtz,Lyn-Marie;Wittlin,Sergio;Delves,Michael;Ottilie,Sabine;Winzeler,ElizabethA.;Smith,Dennis;Fidock,DavidA.;Street,LeslieJ.;Basarab,GregoryS.;Duffy,James;Chibale,Kelly[JournalofMedicinalChemistry,2021,vol.64,#4,p.2291-2309]

[1]CurrentPatentAssignee:ABBVIEINC-US2015/210720,2015,A1Locationinpatent:Paragraph0621

[2]CurrentPatentAssignee:ABBVIEINC-US9777020,2017,B2Locationinpatent:Page/Pagecolumn102

[3]CurrentPatentAssignee:Novartis(w/oSandoz);NOVARTISAG-WO2009/10488,2009,A1Locationinpatent:Page/Pagecolumn47

[4]CurrentPatentAssignee:TAISHOPHARMACEUTICALHOLDINGSCO.,LTD.-EP2881384,2015,A1Locationinpatent:Paragraph0260

1105662-87-0   
tert-butyl3-(2-methoxy-2-oxoethyl)-3-(4-(1R,2S)-2-phenylcyclopropylamino}-piperidin-1-yl)azetidine-1-carboxylate 

[1]CurrentPatentAssignee:INCYTECORP-US2015/225394,2015,A1

1105662-87-0   
tert-butyl3-(2-methoxy-2-oxoethyl)-3-{4-(1R,2S)-2-phenylcyclopropyl(trifluoroacetyl)aminopiperidin-1-yl}azetidine-1-carboxylate 

[1]CurrentPatentAssignee:INCYTECORP-US2015/225394,2015,A1

1105662-87-0   
methyl(3-{4-(1R,2S)-2-phenylcyclopropyl(trifluoroacetyl)aminopiperidin-1-yl}azetidin-3-yl)acetatedihydrochloride 

[1]CurrentPatentAssignee:INCYTECORP-US2015/225394,2015,A1

Literature
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SDS
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Tags:1105662-87-0 Molecular Formula|1105662-87-0 MDL|1105662-87-0 SMILES|1105662-87-0 1-Boc-3-methoxycarbonylmethylene-azetidine