Title: Escin augments the efficacy of gemcitabine through down-regulation of nuclear factor-κB and nuclear factor-κB-regulated gene products in pancreatic cancer both in vitro and in vivo.
Journal: Journal of cancer research and clinical oncology 20120501
Title: [Application of recording SK2 current in human atrial myocytes by perforated patch clamp techniques with the mix of beta-escin and amphotericin B].
Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20120501
Title: [Effects of sodium aescinate on the apoptosis-related genes in lung injury induced by intestinal ischemia reperfusion in rats].
Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20120301
Title: Triterpene saponins of Quillaja saponaria show strong aphicidal and deterrent activity against the pea aphid Acyrthosiphon pisum.
Journal: Pest management science 20120201
Title: 3',4'-Dihydroxyflavonol reduces vascular contraction through Ca²⁺ desensitization in permeabilized rat mesenteric artery.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20120201
Title: Intracellular drug delivery in Leishmania-infected macrophages: Evaluation of saponin-loaded PLGA nanoparticles.
Journal: Journal of drug targeting 20120201
Title: Mixture designs in the optimisation of PLGA nanoparticles: influence of organic phase composition on β-aescin encapsulation.
Journal: Journal of microencapsulation 20120101
Title: β-Escin sodium inhibits inducible nitric oxide synthase expression via downregulation of the JAK/STAT pathway in A549 cells.
Journal: Molecular carcinogenesis 20111201
Title: The impact of sodium aescinate on acute lung injury induced by oleic acid in rats.
Journal: Experimental lung research 20111201
Title: PLGA nanoparticles loaded with the antileishmanial saponin β-aescin: factor influence study and in vitro efficacy evaluation.
Journal: International journal of pharmaceutics 20111125
Title: Protective effect of aescin from the seeds of Aesculus hippocastanum on liver injury induced by endotoxin in mice.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20111115
Title: Synergistic interactions of saponins and monoterpenes in HeLa cells, Cos7 cells and in erythrocytes.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20111015
Title: Protective effect of sodium aescinate on lung injury induced by methyl parathion.
Journal: Human & experimental toxicology 20111001
Title: Apoptosis of human cholangiocarcinoma cell lines induced by β-escin through mitochondrial caspase-dependent pathway.
Journal: Phytotherapy research : PTR 20111001
Title: A new cyclodextrin-grafted viscose loaded with aescin formulations for a cosmeto-textile approach to chronic venous insufficiency.
Journal: Journal of materials science. Materials in medicine 20111001
Title: 19,20-EpDPE, a bioactive CYP450 metabolite of DHA monoacyglyceride, decreases Ca²⁺ sensitivity in human pulmonary arteries.
Journal: American journal of physiology. Heart and circulatory physiology 20111001
Title: The potent anti-inflammatory agent escin does not increase corticosterone secretion and immune cell apoptosis in mice.
Journal: Fitoterapia 20110901
Title: Rho-kinase inhibition attenuates calcium-induced contraction in β-escin but not Triton X-100 permeabilized rabbit femoral artery.
Journal: Journal of muscle research and cell motility 20110901
Title: Aescin: microcirculatory activity. Effects of accessory components on clinical and microcirculatory efficacy.
Journal: Panminerva medica 20110901
Title: Ca(2+)-dependent contraction by the saponoside escin in rat vena cava: implications in venotonic treatment of varicose veins.
Journal: Journal of vascular surgery 20110801
Title: Escin attenuates cerebral edema induced by acute omethoate poisoning.
Journal: Toxicology mechanisms and methods 20110601
Title: Hydrogen sulphide inhibits carbachol-induced contractile responses in β-escin permeabilized guinea-pig taenia caecum.
Journal: European journal of pharmacology 20110511
Title: Escin exerts synergistic anti-inflammatory effects with low doses of glucocorticoids in vivo and in vitro.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20110215
Title: Escin attenuates acute lung injury induced by endotoxin in mice.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20110118
Title: Escin attenuates cognitive deficits and hippocampal injury after transient global cerebral ischemia in mice via regulating certain inflammatory genes.
Journal: Neurochemistry international 20100901
Title: Synergistic effects of beta-aescin and 5-fluorouracil in human hepatocellular carcinoma SMMC-7721 cells.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20100701
Title: Identification of beta-escin as a novel inhibitor of signal transducer and activator of transcription 3/Janus-activated kinase 2 signaling pathway that suppresses proliferation and induces apoptosis in human hepatocellular carcinoma cells.
Journal: The Journal of pharmacology and experimental therapeutics 20100701
Title: Beneficial effects of Aesculus hippocastanum L. seed extract on the body's own antioxidant defense system on subacute administration.
Journal: Journal of ethnopharmacology 20100504
Title: Determination of escin content in androgenic embryos and hairy root culture of Aesculus hippocastanum.
Journal: Pharmaceutical biology 20100501
Title: Simultaneous analysis of isomers of escin saponins in human plasma by liquid chromatography-tandem mass spectrometry: application to a pharmacokinetic study after oral administration.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100401
Title: Effects of escin mixture from the seeds of Aesculus hippocastanum on obesity in mice fed a high fat diet.
Journal: Pharmaceutical biology 20100301
Title: Dual effects of sodium aescinate on vascular tension in rat thoracic aorta.
Journal: Microvascular research 20100101
Title: Beta-escin has potent anti-allergic efficacy and reduces allergic airway inflammation.
Journal: BMC immunology 20100101
Title: Signalling pathways involved in the contractile response to 5-HT in the human pulmonary artery.
Journal: The European respiratory journal 20091201
Title: [Effects of intrathecal escin and clonidine in the treatment of neuropathic pain in rats].
Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20090901
Title: Phosphorylation-dependent autoinhibition of myosin light chain phosphatase accounts for Ca2+ sensitization force of smooth muscle contraction.
Journal: The Journal of biological chemistry 20090807
Title: Pilot postoperative ileus study of escin in cancer patients after colorectal surgery.
Journal: World journal of surgery 20090201
Title: The effects of reactive oxygen species on calcium- and carbachol-induced contractile responses in beta-escin permeabilized rat bladder.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20081201
Title: Beta-escin, a natural triterpenoid saponin from Chinese horse chestnut seeds, depresses HL-60 human leukaemia cell proliferation and induces apoptosis.
Journal: The Journal of pharmacy and pharmacology 20080901
Title: Effects of omega-hydroxylase product on distal human pulmonary arteries.
Journal: American journal of physiology. Heart and circulatory physiology 20080301
Title: Aescin and troxerutin as a successful combination for the treatment of inner ear perfusion disturbances.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20080301
Title: Anti-obesity effects of escins extracted from the seeds of Aesculus turbinata BLUME (Hippocastanaceae).
Journal: Chemical & pharmaceutical bulletin 20080101
Title: Effect of beta-escin sodium on endothelial cells proliferation, migration and apoptosis.
Journal: Vascular pharmacology 20080101
Title: Intracellular calcium stores in beta-escin skinned rat and guinea-pig bladders.
Journal: European journal of pharmacology 20070702
Title: Endothelium protectant and contractile effects of the antivaricose principle escin in rat aorta.
Journal: Vascular pharmacology 20070701
Title: Intestinal inflammation downregulates smooth muscle CPI-17 through induction of TNF-alpha and causes motility disorders.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20070501
Title: Use of solid phase extraction (SPE) to evaluate in vitro skin permeation of aescin.
Journal: Die Pharmazie 20070501
Title: Aescin protection of human vascular endothelial cells exposed to cobalt chloride mimicked hypoxia and inflammatory stimuli.
Journal: Planta medica 20070301
Title: Mechanism underlying H2O2-induced inhibition of acetylcholine-induced contraction in rabbit tracheal smooth muscle.
Journal: European journal of pharmacology 20070227
Title: Pkd2+/- vascular smooth muscles develop exaggerated vasocontraction in response to phenylephrine stimulation.
Journal: Journal of the American Society of Nephrology : JASN 20070201
Title: Identification of novel saponins from edible seeds of Japanese horse chestnut (Aesculus turbinata Blume) after treatment with wooden ashes and their nutraceutical activity.
Journal: Journal of pharmaceutical and biomedical analysis 20060828
Title: Involvement of Rho kinase and protein kinase C in carbachol-induced calcium sensitization in beta-escin skinned rat and guinea-pig bladders.
Journal: British journal of pharmacology 20060601
Title: Beta-escin inhibits colonic aberrant crypt foci formation in rats and regulates the cell cycle growth by inducing p21(waf1/cip1) in colon cancer cells.
Journal: Molecular cancer therapeutics 20060601
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Densitometric thin-layer chromatographic determination of aescin in a herbal medicinal product containing Aesculus and Vitis dry extracts.
Journal: Journal of chromatography. A 20060421
Title: Occupational asthma related to aescin inhalation.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20060301
Title: Medical expulsive treatment of distal-ureteral stones using tamsulosin: a single-center experience.
Journal: Journal of endourology 20060101
Title: Escin: inhibiting inflammation and promoting gastrointestinal transit to attenuate formation of postoperative adhesions.
Journal: World journal of surgery 20051201
Title: The use of tamsulosin in the medical treatment of ureteral calculi: where do we stand?
Journal: Urological research 20051201
Title: Effects of beta-Aescin on the expression of nuclear factor-kappaB and tumor necrosis factor-alpha after traumatic brain injury in rats.
Journal: Journal of Zhejiang University. Science. B 20050101
Title: Characteristic fragmentation behavior of some glucuronide-type triterpenoid saponins using electrospray ionization tandem mass spectrometry.
Journal: Rapid communications in mass spectrometry : RCM 20050101
Title: Evaluation of biosurfactants for crude oil contaminated soil washing.
Journal: Chemosphere 20041201
Title: Development of cultured rabbit corneal epithelium for drug permeation studies: a comparison with excised rabbit cornea.
Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20041201
Title: Effects of escin on indinavir crystallization time in the urine of patients with HIV-I infection: a multicenter, randomized, open-label, controlled, four-period crossover trial.
Journal: Clinical therapeutics 20041201
Title: [Clinical effect of escin on patients with cutaneous pruritus caused by blood stasis and wind-dryness].
Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20041101
Title: Beta-escin diminishes voltage-gated calcium current rundown in perforated patch-clamp recordings from rat primary afferent neurons.
Journal: Journal of neuroscience methods 20041015
Title: Actions downstream of cyclic GMP/protein kinase G can reverse protein kinase C-mediated phosphorylation of CPI-17 and Ca²⁺ sensitization in smooth muscle.
Journal: The Journal of biological chemistry 20040709
Title: Differential effects of FK506 and cyclosporin A on catecholamine release from bovine adrenal chromaffin cells.
Journal: Autonomic & autacoid pharmacology 20040701
Title: Mechanisms involved in carbachol-induced Ca(2+) sensitization of contractile elements in rat proximal and distal colon.
Journal: British journal of pharmacology 20040601
Title: Protective effects of sodium beta-aescin on ischemia-reperfusion injury in rat brain.
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20040601
Title: Over-expression of FK506-binding protein FKBP12.6 alters excitation-contraction coupling in adult rabbit cardiomyocytes.
Journal: The Journal of physiology 20040501
Title: Microcirculatory efficacy of topical treatment with aescin + essential phospholipids gel in venous insufficiency and hypertension: new clinical observations.
Journal: Angiology 20040101
Title: Microcirculatory efficacy of topical treatment with aescin + essential phospholipids gel on transcutaneous PO2 in venous insufficiency.
Journal: Angiology 20040101
Title: Variations in plasma free radicals with topical aescin + essential phospholipids gel in venous hypertension: new clinical data.
Journal: Angiology 20040101
Title: Efficacy of topical treatment with aescin + essential phospholipids gel in a microcirculatory model of venous insufficiency.
Journal: Angiology 20040101
Title: Efficacy of topical treatment with aescin + essential phospholipids gel in venous insufficiency and hypertension.
Journal: Angiology 20040101
Title: Efficacy of topical treatment with aescin + essential phospholipids gel on capillary fragility.
Journal: Angiology 20040101
Title: Perforated patch recording of L-type calcium current with beta-escin in guinea pig ventricular myocytes.
Journal: Acta pharmacologica Sinica 20031101
Title: Dependence of Ca2+-induced contraction on ATP in alpha-toxin-permeabilized preparations of rat femoral artery.
Journal: Journal of pharmacological sciences 20031001
Title: [Inhibitory effects of salviae miltiorrhizae and beta-aescinom natrium on the postburn acute lung injury in rats].
Journal: Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns 20031001
Title: Characterization of alpha-soluble N-ethylmaleimide-sensitive fusion attachment protein in alveolar type II cells: implications in lung surfactant secretion.
Journal: American journal of respiratory cell and molecular biology 20030901
Title: Effects of adenovirus-mediated sorcin overexpression on excitation-contraction coupling in isolated rabbit cardiomyocytes.
Journal: Circulation research 20030725
Title: Measurement of the dissociation constant of Fluo-3 for Ca2+ in isolated rabbit cardiomyocytes using Ca2+ wave characteristics.
Journal: Cell calcium 20030701
Title: CaM kinase IIalpha mediates norepinephrine-induced translocation of cytosolic phospholipase A2 to the nuclear envelope.
Journal: Journal of cell science 20030115
Title: [Plant preparations of Sofarma in gynecological practice].
Journal: Akusherstvo i ginekologiia 20030101
Title: Sphingosylphosphorylcholine is a novel messenger for Rho-kinase-mediated Ca2+ sensitization in the bovine cerebral artery: unimportant role for protein kinase C.
Journal: Circulation research 20020726
Title: Escin/diethylammonium salicylate/heparin combination gels for the topical treatment of acute impact injuries: a randomised, double blind, placebo controlled, multicentre study.
Journal: British journal of sports medicine 20020601
Title: Xestospongin C, a novel blocker of IP3 receptor, attenuates the increase in cytosolic calcium level and degranulation that is induced by antigen in RBL-2H3 mast cells.
Journal: British journal of pharmacology 20020401
Title: Extensive skinning of cell membrane diminishes the force-inhibiting effect of okadaic acid on smooth muscles of Guinea pig hepatic portal vein.
Journal: The Japanese journal of physiology 20020401
Title: Comparative study of Venostasin and Pycnogenol in chronic venous insufficiency.
Journal: Phytotherapy research : PTR 20020301
Title: [Pathogenetic basis for using prodectin and teonicol, redergin and aescuzan in complex treatment of chronic gastritis].
Journal: Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20020101
Title: Aescin: pharmacology, pharmacokinetics and therapeutic profile.
Journal: Pharmacological research 20010901
Title: Mechanisms of direct inhibitory action of ketamine on vascular smooth muscle in mesenteric resistance arteries.
Journal: Anesthesiology 20010801
Title: Efficacy and tolerability of escin/diethylamine salicylate combination gels in patients with blunt injuries of the extremities.
Journal: International journal of sports medicine 20010801
Title: Regulation by GDI of RhoA/Rho-kinase-induced Ca2+ sensitization of smooth muscle myosin II.
Journal: American journal of physiology. Cell physiology 20010701
Title: Effects of halothane on sarcoplasmic reticulum calcium release channels in porcine airway smooth muscle cells.
Journal: Anesthesiology 20010701
Title: Synexin and GTP increase surfactant secretion in permeabilized alveolar type II cells.
Journal: American journal of physiology. Lung cellular and molecular physiology 20010501
Title: Responsiveness of human varicose saphenous veins to vasoactive agents.
Journal: British journal of clinical pharmacology 20010301
Title: Inhibition of capacitative calcium entry is not obligatory for relaxation of the mouse anococcygeus by the NO/cyclic GMP signalling pathway.
Journal: British journal of pharmacology 20010201
Title: [Systemic enzyme therapy in the treatment and prevention of post-traumatic and postoperative swelling].
Journal: Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca 20010101
Title: Rational therapy of chronic venous insufficiency--chances and limits of the therapeutic use of horse-chestnut seeds extract.
Journal: BMC cardiovascular disorders 20010101
