[1]CurrentPatentAssignee:GILEADSCIENCESINC-US2009/82330,2009,A1Locationinpatent:Page/Pagecolumn29
Title: A novel reaction mediated by human aldehyde oxidase: amide hydrolysis of GDC-0834.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20150601
Title: Potent and selective Bruton's tyrosine kinase inhibitors: discovery of GDC-0834.
Journal: Bioorganic & medicinal chemistry letters 20150315
Title: Bruton's tyrosine kinase inhibitors: approaches to potent and selective inhibition, preclinical and clinical evaluation for inflammatory diseases and B cell malignancies.
Journal: Journal of medicinal chemistry 20120524
Title: Significant species difference in amide hydrolysis of GDC-0834, a novel potent and selective Bruton's tyrosine kinase inhibitor.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20111001
Title: Antiarthritis effect of a novel Bruton's tyrosine kinase (BTK) inhibitor in rat collagen-induced arthritis and mechanism-based pharmacokinetic/pharmacodynamic modeling: relationships between inhibition of BTK phosphorylation and efficacy.
Journal: The Journal of pharmacology and experimental therapeutics 20110701
Title: Liu L, et al. Antiarthritis effect of a novel Bruton's tyrosine kinase (BTK) inhibitor in rat collagen-induced arthritis and mechanism-based pharmacokinetic/pharmacodynamic modeling: relationships between inhibition of BTK phosphorylation and efficacy. J
Title: Sodhi JK, et al. A novel reaction mediated by human aldehyde oxidase: amide hydrolysis of GDC-0834. Drug Metab Dispos. 2015 Jun;43(6):908-15
