Title: A small molecule inhibitor of mutant IDH2 rescues cardiomyopathy in a D-2-hydroxyglutaric aciduria type II mouse model.
Journal: Journal of inherited metabolic disease 20160101
Title: N-methylnicotinamide is an endogenous probe for evaluation of drug-drug interactions involving multidrug and toxin extrusions (MATE1 and MATE2-K).
Journal: Clinical pharmacology and therapeutics 20121101
Title: Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Journal: Journal of medicinal chemistry 20120524
Title: Nitric oxide production and endothelium-dependent vasorelaxation ameliorated by N1-methylnicotinamide in human blood vessels.
Journal: Hypertension (Dallas, Tex. : 1979) 20120401
Title: In vitro and in silico strategies to identify OATP1B1 inhibitors and predict clinical drug-drug interactions.
Journal: Pharmaceutical research 20120201
Title: Beneficial metabolic effects of 2',3',5'-tri-acetyl-N6- (3-hydroxylaniline) adenosine in the liver and plasma of hyperlipidemic hamsters.
Journal: PloS one 20120101
Title: Nicotinamide, NAD(P)(H), and Methyl-Group Homeostasis Evolved and Became a Determinant of Ageing Diseases: Hypotheses and Lessons from Pellagra.
Journal: Current gerontology and geriatrics research 20120101
Title: Characterization and crystallization of mouse aldehyde oxidase 3: from mouse liver to Escherichia coli heterologous protein expression.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20111001
Title: Two different hydrogen bond donor ligands together: a selectivity improvement in organometallic {Re(CO)3} anion hosts.
Journal: Inorganic chemistry 20110905
Title: Characterization of organic anion-transporting polypeptide (Oatp) 1a1 and 1a4 null mice reveals altered transport function and urinary metabolomic profiles.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20110801
Title: Metabolomic assessment with CE-MS of the nutraceutical effect of Cystoseira spp extracts in an animal model.
Journal: Electrophoresis 20110801
Title: Identification of urinary biomarkers from X-irradiated mice using NMR spectroscopy.
Journal: Radiation research 20110501
Title: Fluorescence Spectrometric Determination of Drugs Containing α-Methylene Sulfone/Sulfonamide Functional Groups Using N-Methylnicotinamide Chloride as a Fluorogenic Agent.
Journal: International journal of analytical chemistry 20110101
Title: Nutritional and metabolic status of children with autism vs. neurotypical children, and the association with autism severity.
Journal: Nutrition & metabolism 20110101
Title: An insight into the metabolic responses of ultra-small superparamagnetic particles of iron oxide using metabonomic analysis of biofluids.
Journal: Nanotechnology 20101001
Title: A novel pathway for nicotine degradation by Aspergillus oryzae 112822 isolated from tobacco leaves.
Journal: Research in microbiology 20100901
Title: Urinary metabolic phenotyping differentiates children with autism from their unaffected siblings and age-matched controls.
Journal: Journal of proteome research 20100604
Title: Protective effect of nicotinamide against poly(ADP-ribose) polymerase-1-mediated astrocyte death depends on its transporter-mediated uptake.
Journal: Life sciences 20100424
Title: Diaqua-bis(5-bromo-2-hydroxy-benzoato)bis-(N-methyl-nicotinamide)zinc(II).
Journal: Acta crystallographica. Section E, Structure reports online 20100401
Title: Development of a hydrophilic liquid interaction chromatography-high-performance liquid chromatography-tandem mass spectrometry based stable isotope dilution analysis and pharmacokinetic studies on bioactive pyridines in human plasma and urine after coffee consumption.
Journal: Analytical chemistry 20100215
Title: Identification of hypoxanthine as a urine marker for non-Hodgkin lymphoma by low-mass-ion profiling.
Journal: BMC cancer 20100101
Title: Effect of taurine supplementation on hyperhomocysteinemia and markers of oxidative stress in high fructose diet induced insulin resistance.
Journal: Diabetology & metabolic syndrome 20100101
Title: A metabonomic comparison of urinary changes in Zucker and GK rats.
Journal: Journal of biomedicine & biotechnology 20100101
Title: Nicotinamide and its metabolite N-methylnicotinamide increase skin vascular permeability in rats.
Journal: Clinical and experimental dermatology 20090401
Title: Carrier-mediated uptake of 1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazolium bromide (YM155 monobromide), a novel small-molecule survivin suppressant, into human solid tumor and lymphoma cells.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20090301
Title: Gastroduodenal mucosal defense.
Journal: Current gastroenterology reports 20081201
Title: Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Journal: Journal of medicinal chemistry 20081009
Title: Development of oxidative stress by cytochrome P450 induction in rodents is selective for barbiturates and related to loss of pyridine nucleotide-dependent protective systems.
Journal: The Journal of biological chemistry 20080620
Title: Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Journal: Journal of medicinal chemistry 20080612
Title: Dietary and genetic compromise in folate availability reduces acetylcholine, cognitive performance and increases aggression: critical role of S-adenosyl methionine.
Journal: The journal of nutrition, health & aging 20080401
Title: N-methylnicotinamide failed to induce endothelial prostacyclin release in perfused rat hindquarters.
Journal: Pharmacological reports : PR 20080101
Title: Effect of dronedarone on renal function in healthy subjects.
Journal: British journal of clinical pharmacology 20071201
Title: 1-Methylnicotinamide stimulates cell growth and inhibits hemoglobin synthesis in differentiating murine erythroleukemia cells.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20071201
Title: Nitroso-imidacloprid irreversibly inhibits rabbit aldehyde oxidase.
Journal: Chemical research in toxicology 20071201
Title: Functional characterization of testis-specific rodent multidrug and toxic compound extrusion 2, a class III MATE-type polyspecific H+/organic cation exporter.
Journal: American journal of physiology. Cell physiology 20071101
Title: The comparative bioavailability of an extended-release niacin and lovastatin fixed dose combination tablet versus extended-release niacin tablet, lovastatin tablet and a combination of extended-release niacin tablet and lovastatin tablet.
Journal: Biopharmaceutics & drug disposition 20070901
Title: N-methylnicotinamide inhibits arterial thrombosis in hypertensive rats.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20070901
Title: Plasma and urine pharmacokinetics of niacin and its metabolites from an extended-release niacin formulation.
Journal: International journal of clinical pharmacology and therapeutics 20070801
Title: Effect of the rate of niacin administration on the plasma and urine pharmacokinetics of niacin and its metabolites.
Journal: Journal of clinical pharmacology 20070601
Title: Niacin nutritional status in HIV type 1-positive children: preliminary data.
Journal: Journal of pediatric gastroenterology and nutrition 20070501
Title: A metabolomic comparison of urinary changes in type 2 diabetes in mouse, rat, and human.
Journal: Physiological genomics 20070424
Title: Beyond lipids, pharmacological PPARalpha activation has important effects on amino acid metabolism as studied in the rat.
Journal: American journal of physiology. Endocrinology and metabolism 20070401
Title: Metabonomics evaluations of age-related changes in the urinary compositions of male Sprague Dawley rats and effects of data normalization methods on statistical and quantitative analysis.
Journal: BMC bioinformatics 20070101
Title: Changes in vitamin status of Indian Antarctic expeditioners during a one-month stay in Austral Summer.
Journal: Wilderness & environmental medicine 20070101
Title: 1H-NMR metabolic profiling of human neonatal urine.
Journal: Magma (New York, N.Y.) 20061201
Title: A metabonomics study of the hepatotoxicants galactosamine, methylene dianiline and clofibrate in rats.
Journal: Basic & clinical pharmacology & toxicology 20060901
Title: Characteristics of thiamine uptake by the BeWo human trophoblast cell line.
Journal: Journal of biochemistry and molecular biology 20060731
Title: Effect of standard nicotinamide in the prevention of type 1 diabetes in first degree relatives of persons with type 1 diabetes.
Journal: Autoimmunity 20060601
Title: Tetraethylammonium and nicotine transport by the Malpighian tubules of insects.
Journal: Journal of insect physiology 20060501
Title: Molecular tweezer and clip in aqueous solution: unexpected self-assembly, powerful host-guest complex formation, quantum chemical 1H NMR shift calculation.
Journal: Journal of the American Chemical Society 20060412
Title: The regulation and inhibition of 17beta-hydroxysteroid dehydrogenase in breast cancer.
Journal: Molecular and cellular endocrinology 20060327
Title: Evaluation of volatile ion-pair reagents for the liquid chromatography-mass spectrometry analysis of polar compounds and its application to the determination of methadone in human plasma.
Journal: Journal of pharmaceutical and biomedical analysis 20060224
Title: Liquid chromatographic/mass spectrometric procedure for measurement of NAD catabolites in human and rat plasma and urine.
Journal: Nucleosides, nucleotides & nucleic acids 20060101
Title: Electron transfer within complex II. Succinate:ubiquinone oxidoreductase of Escherichia coli.
Journal: The Journal of biological chemistry 20050930
Title: Molecular and functional characterization of an Na+-independent choline transporter in rat astrocytes.
Journal: Journal of neurochemistry 20050901
Title: Increased tubular organic ion clearance following chronic ACE inhibition in patients with type 1 diabetes.
Journal: Kidney international 20050601
Title: Tryptophan-NAD+ pathway metabolites as putative biomarkers and predictors of peroxisome proliferation.
Journal: Archives of toxicology 20050401
Title: Parkinson's disease: the first common neurological disease due to auto-intoxication?
Journal: QJM : monthly journal of the Association of Physicians 20050301
Title: Identification of aldehyde oxidase as the neonicotinoid nitroreductase.
Journal: Chemical research in toxicology 20050201
Title: Nicotinamide homeostasis: a xenobiotic pathway that is key to development and degenerative diseases.
Journal: Medical hypotheses 20050101
Title: [Pellagra].
Journal: Sante (Montrouge, France) 20050101
Title: The effect of a series of organic cations upon the plasmalemmal serotonin transporter, SERT.
Journal: Life sciences 20041119
Title: The role of advanced glycation in reduced organic cation transport associated with experimental diabetes.
Journal: The Journal of pharmacology and experimental therapeutics 20041101
Title: Niacin metabolite excretion in alcoholic pellagra and AIDS patients with and without diarrhea.
Journal: Nutrition (Burbank, Los Angeles County, Calif.) 20040901
Title: Effects of feeding and body weight loss on the 1H-NMR-based urine metabolic profiles of male Wistar Han rats: implications for biomarker discovery.
Journal: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20040101
Title: Development of a multivariate statistical model to predict peroxisome proliferation in the rat, based on urinary 1H-NMR spectral patterns.
Journal: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20040101
Title: Molecular tweezers and clips as synthetic receptors. Molecular recognition and dynamics in receptor-substrate complexes.
Journal: Accounts of chemical research 20031201
Title: Reduced tubular cation transport in diabetes: prevented by ACE inhibition.
Journal: Kidney international 20030601
Title: Influence of molecular structure on substrate binding to the human organic cation transporter, hOCT1.
Journal: Molecular pharmacology 20030301
Title: Evidence for a carrier-mediated mechanism for thiamine transport to human jejunal basolateral membrane vesicles.
Journal: Digestive diseases and sciences 20030101
Title: [Connection between changing the vitamin and immune status and the character of the throat microflora in patients with chronic tonsillitis].
Journal: Otolaryngologia polska = The Polish otolaryngology 20030101
Title: Potential urinary and plasma biomarkers of peroxisome proliferation in the rat: identification of N-methylnicotinamide and N-methyl-4-pyridone-3-carboxamide by 1H nuclear magnetic resonance and high performance liquid chromatography.
Journal: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20030101
Title: Cellular and molecular aspects of thiamin uptake by human liver cells: studies with cultured HepG2 cells.
Journal: Biochimica et biophysica acta 20021223
Title: Functional characterization of mouse cation transporter mOCT2 compared with mOCT1.
Journal: Biochemical and biophysical research communications 20020823
Title: Intramolecular electron transfer in cytochrome cd(1) nitrite reductase from Pseudomonas stutzeri; kinetics and thermodynamics.
Journal: Biophysical chemistry 20020710
Title: cDNA cloning, functional characterization, and tissue distribution of an alternatively spliced variant of organic cation transporter hOCT2 predominantly expressed in the human kidney.
Journal: Journal of the American Society of Nephrology : JASN 20020701
Title: Copper complexes with bioactive ligands. Part II--Antifungal activity.
Journal: Folia microbiologica 20020101
Title: Self-assembly of polymer and sheet structures from palladium(II) complexes by hydrogen bonding between carboxamide substituents.
Journal: Inorganic chemistry 20011119
Title: Ventricular choline transport: a role for organic cation transporter 2 expressed in choroid plexus.
Journal: The Journal of biological chemistry 20011109
Title: Mechanism of thiamine uptake by human jejunal brush-border membrane vesicles.
Journal: American journal of physiology. Cell physiology 20010901
Title: Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.
Journal: American journal of physiology. Renal physiology 20010901
Title: Intramolecular electron transfer from c heme to d1 heme in bacterial cytochrome cd1 nitrite reductase occurs over the same distances at very different rates depending on the source of the enzyme.
Journal: Biochemistry 20010724
Title: Effects of dietary pyrazinamide, an antituberculosis agent, on the metabolism of tryptophan to niacin and of tryptophan to serotonin in rats.
Journal: Bioscience, biotechnology, and biochemistry 20010601
Title: The metabolism of nicotinamide in human liver cirrhosis: a study on N-methylnicotinamide and 2-pyridone-5-carboxamide production.
Journal: The American journal of gastroenterology 20010401
Title: Cytosolic xanthine oxidoreductase mediated bioactivation of ethanol to acetaldehyde and free radicals in rat breast tissue. Its potential role in alcohol-promoted mammary cancer.
Journal: Toxicology 20010307
Title: Molecular and physiological evidence for multifunctionality of carnitine/organic cation transporter OCTN2.
Journal: Molecular pharmacology 20010201
Title: Hepatic uptake of synthetic chlorogenic acid derivatives by the organic anion transport proteins.
Journal: The Journal of pharmacology and experimental therapeutics 20010101
Title: Transport of [3H]MPP+ in an immortalized rat brain microvessel endothelial cell line (RBE 4).
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20010101
Title: Rat ventral prostate xanthine oxidase bioactivation of ethanol to acetaldehyde and 1-hydroxyethyl free radicals: analysis of its potential role in heavy alcohol drinking tumor-promoting effects.
Journal: Teratogenesis, carcinogenesis, and mutagenesis 20010101
Title: Copper complexes with bioactive ligands Part I--Antimicrobial activity.
Journal: Folia microbiologica 20010101
Title: Functional characterization of an organic cation transporter (hOCT1) in a transiently transfected human cell line (HeLa).
Journal: The Journal of pharmacology and experimental therapeutics 19980701
Title: Cloning and characterization of two human polyspecific organic cation transporters.
Journal: DNA and cell biology 19970701
Title: Gentamicin nephrotoxicity. I. Degree and permanence of acquired insensitivity.
Journal: The Journal of laboratory and clinical medicine 19821001