Catalog No.:AA000EZ2

1146963-51-0 | N-(2,4-Dimethylphenyl)-2,2,2-trifluoro-N'-[(1E)-(3-methoxyphenyl)methylidene]acetohydrazide

Name: Name:N-(2,4-Dimethylphenyl)-2,2,2-trifluoro-N'-[(1E)-(3-methoxyphenyl)methylidene]acetohydrazide
Brand: AABLOCKS
SKU: AA000EZ2
Availability: InStock
Rating: 90 (10 reviews)

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250mg

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in stock

$29.00 $21.00

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98%

in stock

$74.00 $52.00

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98%

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$247.00 $173.00

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Technical Information
Properties
Literature
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Technical Information
Properties
Literature

Technical Information

Catalog Number:

AA000EZ2

Chemical Name:

N-(2,4-Dimethylphenyl)-2,2,2-trifluoro-N'-[(1E)-(3-methoxyphenyl)methylidene]acetohydrazide

CAS Number:

1146963-51-0

Molecular Formula:

C18H17F3N2O2

Molecular Weight:

350.3350

MDL Number:

MFCD25976644

SMILES:

COc1cccc(c1)C=NN(C(=O)C(F)(F)F)c1ccc(cc1C)C

Properties

Computed Properties

Complexity:

481

Covalently-Bonded Unit Count:

Defined Bond Stereocenter Count:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Rotatable Bond Count:

XLogP3:

4.7

Literature

Title: Wang M, et al. The first synthesis of 1CJ147, a new potential PET agent for imaging of Alzheimer's disease. Bioorg Med Chem Lett. 2013 Jan 15;23(2):524-7.

Title: Prior M, et al. The neurotrophic compound J147 reverses cognitive impairment in aged Alzheimer's disease mice. Alzheimers Res Ther. 2013 May 14;5(3):25.

Title: Chen Q, et al. A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease. PLoS One. 2011;6(12):e27865.

Title: Prior M, et al. Selecting for neurogenic potential as an alternative for Alzheimer's disease drug discovery. Alzheimers Dement. 2016 Jun;12(6):678-86.

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SDS