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114798-26-4,MFCD00865831
Catalog No.:AA000F5D
114798-26-4 | Losartan
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250mg
98%
in stock  
$7.00   $5.00
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1g
98%
in stock  
$14.00   $10.00
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5g
98%
in stock  
$26.00   $18.00
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100g
98%
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$87.00   $61.00
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Technical Information
Catalog Number:
AA000F5D
Chemical Name:
Losartan
CAS Number:
114798-26-4
Molecular Formula:
C22H23ClN6O
Molecular Weight:
422.9106
MDL Number:
MFCD00865831
IUPAC Name:
[2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol
InChI:
InChI=1S/C22H23ClN6O/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22/h4-7,9-12,30H,2-3,8,13-14H2,1H3,(H,25,26,27,28)
InChI Key:
PSIFNNKUMBGKDQ-UHFFFAOYSA-N
SMILES:
CCCCc1nc(c(n1Cc1ccc(cc1)c1ccccc1c1n[nH]nn1)CO)Cl
EC Number:
601-329-8
UNII:
JMS50MPO89
NSC Number:
758699
Properties
Computed Properties
 
Complexity:
520  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
422.162g/mol
Formal Charge:
0
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
422.917g/mol
Monoisotopic Mass:
422.162g/mol
Rotatable Bond Count:
8  
Topological Polar Surface Area:
92.5A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
4.3  

Synonyms
 
2-Butyl-4-chloro-1-((2'-(1H-etrazol-5-yl) (1,1'-biphenyl)-4-yl)methyl)-1H-imidazole-5-methanol 
Cozaar 
MK954 
STL419984 
2-butyl-4-chloro-1-[p-(o-1H-tetrazol-5ylphenyl)benzyl]imidazole-5-methanol 
AKOS015917390 
AKOS015994740 
Tox21_111435_1 
AB07507 
API0007066 
BCP9000861 
CS-2116 
DB00678 
Monopotassium Salt, Losartan 
KS-5004 
MCULE-5204931675 
NSC-758699 
2-n-butyl-4-chloro-5-hydroxymethyl-1-[[2'-(1H-tetrazol-5-yl)-biphenyl-4-yl]methyl]imidazole 
NCGC00095125-02 
NCGC00095125-03 
NCGC00095125-05 
(2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1H-imidazol-5-yl)methanol 
2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl-1H-imidazole-5-methanol 
AK326126 
Potassium, Losartan 
AN-15301 
HY-17512 
I497 
LS-78746 
SC-47229 
SBI-0206766.P001 
AB0013723 
RT-013597 
CAS_114798-26-4 
FT-0631074 
Salt, Losartan Monopotassium 
C07072 
D08146 
54244-EP2269989A1 
54244-EP2270011A1 
54244-EP2272841A1 
54244-EP2277879A1 
54244-EP2287165A2 
54244-EP2287166A2 
54244-EP2292620A2 
54244-EP2295053A1 
losartan 
54244-EP2295406A1 
54244-EP2298772A1 
54244-EP2298776A1 
54244-EP2298779A1 
54244-EP2301923A1 
54244-EP2301931A1 
54244-EP2301936A1 
54244-EP2305219A1 
54244-EP2308562A2 
54244-EP2308839A1 
114798-26-4 
AB01563296_01 
798L264 
A803239 
L000351 
I14-9710 
SR-01000763170-3 
SR-01000763170-4 
BRD-K76205745-001-02-5 
BRD-K76205745-001-04-1 
F2173-0506 
DUP 89 
[2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-4-imidazolyl]methanol 
2-butyl-4-chloro-5-hydroxymethyl-1-[(2'-(1H-tetrazol-5-yl)-biphenyl-4-yl)methyl]imidazole 
2-butyl-4-chloro-5-hydroxymethyl-1-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]imidazole 
(1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol 
(1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol 
(1-((2'-(2h-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1h-imidazol-5-yl)methanol 
(2-butyl-4-chloro-1-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanol 
[2-butyl-4-chloro-1-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1H-imidazol-5-yl]methanol 
{2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-imidazol-4-yl}-methanol 
1H-Imidazole-5-methanol, 2-butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]- (9CI) 
Lortaan 
2-butyl-4-chloro-1-[[2'-(2h-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1h-imidazole-5-methanol 
2-butyl-4-chloro-5-(hydroxymethyl)-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]imidazole 
allisartan 
Lacidipine 
Angizaar 
Losartic 
Mixture Name 
Potassium, Losartan 
Cozaar (TN) 
losartan monopotassium 
LOSARTAN POTASSIUM 
CHEMBL191 
D03AQG 
D0DD0K 
DuP753 
Monopotassium Salt, Losartan 
Salt, Losartan Monopotassium 
C22-H23-Cl-N6-O 
CID3961 
MK 954 
CL23623 
Cozaar 
CS-O-10833 
1645A 
B1072 
D019808 
(2-Butyl-4-chloro-1-((4-(2-(2H-1,2,3,4-tetrazol-5-yl)phenyl)phenyl)methyl)-1H-imidazol-5-yl)methanol 
1-[1-[[2'-(2H-Tetrazol-5-yl)biphenyl-4-yl]methyl]-2-butyl-4-chloro-1H-imidazol-5-yl]methanol 
1h-imidazol-5-metanol, 2-butil-4-cloro-1-[[2'-(2h-tetrazol-5-il)[1,1'-bifenil]-4-il]metil]- 
1H-Imidazole-5-methanol 2-butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1 1'-biphenyl]-4-yl]methyl]-(9CI) 
1H-Imidazole-5-methanol, 2-butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-(9CI) 
2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)-1 1'-biphenyl-4-yl]methyl]-1H-imidazole-5-methanol 
DuP 753 
Hyzaar 
90776-59-3 
LSN 
Losartan [INN:BAN] 
Losartan monopotassium salt 
UNII-JMS50MPO89 
C22H23ClN6O 
DuP-753 
CHEBI:6541 
MK-954 
JMS50MPO89 
2-Butyl-4-chloro-1-((2'-(1H-etrazol-5-yl) (1,1'-biphenyl)-4-yl)methyl)-1H-imidazole-5-methanol 
DuP-753 
DuP 753 
MFCD00865831 
(2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanol 
[2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol 
2-n-butyl-4-chloro-5-hydroxymethyl-1-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]imidazole 
NCGC00095125-01 
DSSTox_CID_3227 
DSSTox_RID_76933 
DSSTox_GSID_23227 
(1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol 
DuP753 
[2-butyl-5-chloranyl-3-[[4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol 
1H-Imidazole-5-methanol, 2-butyl-4-chloro-1-((2'-(1H-tetrazol-5-yl)(1,1'- biphenyl)-4-yl)methyl)- 
Q-201321 
[3H]losartan 
HSDB 7043 
Losartan (INN) 
Losartic (TN) 
1H-imidazole-5-methanol, 2-butyl-4-chloro-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]- 
2-BUTYL-4-CHLORO-1-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1H-IMIDAZOLE-5-METHANOL 
[3H]-losartan 
Losartan 
CAS-114798-26-4 
MK954 
SR-01000763170 
[2-butyl-5-chloro-3-[[4-[2-(1H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol 
PubChem9176 
Dup89 
Spectrum_001713 
SCHEMBL60 
Spectrum2_001677 
Spectrum3_000998 
Losartan Monopotassium Salt 
Spectrum4_001126 
Spectrum5_001466 
Epitope ID:140137 
EC 601-329-8 
AC1L1H3Q 
Oprea1_644635 
US9624243, Losartin 
BSPBio_002695 
GTPL590 
KBioGR_001611 
Losartan Potassium 
KBioSS_002193 
BIDD:GT0286 
SPECTRUM1504268 
SPBio_001893 
DUP-89 
GTPL3941 
Jsp001094 
DTXSID7023227 
BDBM82258 
CTK8E7663 
MK 954 
KBio2_002193 
KBio2_004761 
KBio2_007329 
KBio3_001915 
PSIFNNKUMBGKDQ-UHFFFAOYSA-N 
BCPP000183 
BDBM318822 
HMS1922J13 
HMS2093E22 
HMS3715L11 
MK-954 
Pharmakon1600-01504268 
BCP27731 
KS-00000GI2 
NSC_3961 
ZINC3873160 
Tox21_111435 
BG0556 
CCG-39095 
GP6564 
NSC758699 
Literature

Title: Perindopril, fosinopril and losartan inhibited the progression of diethylnitrosamine-induced hepatocellular carcinoma in mice via the inactivation of nuclear transcription factor kappa-B.

Journal: Toxicology letters 20181001

Title: Angiotensin II facilitates neointimal formation by increasing vascular smooth muscle cell migration: Involvement of APE/Ref-1-mediated overexpression of sphingosine-1-phosphate receptor 1.

Journal: Toxicology and applied pharmacology 20180515

Title: Role of RAS/Wnt/β-catenin axis activation in the pathogenesis of podocyte injury and tubulo-interstitial nephropathy.

Journal: Chemico-biological interactions 20170801

Title: Mitogen-activated protein kinase p38 target regenerating islet-derived 3γ expression is upregulated in cardiac inflammatory response in the rat heart.

Journal: Physiological reports 20161001

Title: Investigation into the interaction of losartan with human serum albumin and glycated human serum albumin by spectroscopic and molecular dynamics simulation techniques: A comparison study.

Journal: Chemico-biological interactions 20160925

Title: [Mechanism of losartan suppressing vascular calcification in rat aortic artery].

Journal: Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20160801

Title: Role of the Na+/H+ exchanger 3 in angiotensin II-induced hypertension in NHE3-deficient mice with transgenic rescue of NHE3 in small intestines.

Journal: Physiological reports 20151101

Title: Perinatally administered losartan augments renal ACE2 expression but not cardiac or renal Mas receptor in spontaneously hypertensive rats.

Journal: Journal of cellular and molecular medicine 20150801

Title: Identification and Functional Assessment of a New CYP2C9 Allelic Variant CYP2C9*59.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20150801

Title: Losartan attenuates paraquat-induced pulmonary fibrosis in rats.

Journal: Human & experimental toxicology 20150501

Title: TSC-22 up-regulates collagen 3a1 gene expression in the rat heart.

Journal: BMC cardiovascular disorders 20150101

Title: Hypoxia induces dysregulation of local renin-angiotensin system in mouse Lewis lung carcinoma cells.

Journal: Genetics and molecular research : GMR 20141212

Title: Oral administration of bisphenol A induces high blood pressure through angiotensin II/CaMKII-dependent uncoupling of eNOS.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20141101

Title: Chronic infusion of enalaprilat into hypothalamic paraventricular nucleus attenuates angiotensin II-induced hypertension and cardiac hypertrophy by restoring neurotransmitters and cytokines.

Journal: Toxicology and applied pharmacology 20140201

Title: Involvement of the HIF-1α and Wnt/β-catenin pathways in the protective effects of losartan on fatty liver graft with ischaemia/reperfusion injury.

Journal: Clinical science (London, England : 1979) 20140101

Title: Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11).

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20131201

Title: A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20131101

Title: Rational design, efficient syntheses and biological evaluation of N,N'-symmetrically bis-substituted butylimidazole analogs as a new class of potent Angiotensin II receptor blockers.

Journal: European journal of medicinal chemistry 20130401

Title: Treatment with low-dose atorvastatin, losartan, and their combination increases expression of vasoactive-related genes in rat aortas.

Journal: Journal of cardiovascular pharmacology and therapeutics 20130301

Title: Epigallocatechin gallate, the major component of polyphenols in green tea, inhibits telomere attrition mediated cardiomyocyte apoptosis in cardiac hypertrophy.

Journal: International journal of cardiology 20130120

Title: Angiotensin type 1 receptor autoantibody from preeclamptic patients induces human fetoplacental vasoconstriction.

Journal: Journal of cellular physiology 20130101

Title: Pro-inflammatory role of angiotensin II in mercuric chloride-induced nephropathy in rats.

Journal: Journal of immunotoxicology 20130101

Title: Recurrent exposure to subclinical lipopolysaccharide increases mortality and induces cardiac fibrosis in mice.

Journal: PloS one 20130101

Title: Impaired endocytosis in proximal tubule from subchronic exposure to cadmium involves angiotensin II type 1 and cubilin receptors.

Journal: BMC nephrology 20130101

Title: Transient prehypertensive treatment in spontaneously hypertensive rats: a comparison of losartan and amlodipine regarding long-term blood pressure, cardiac and renal protection.

Journal: International journal of molecular medicine 20121201

Title: Recent developments in the diagnosis of Marfan syndrome and related disorders.

Journal: The Medical journal of Australia 20121105

Title: Podocyte detachment and reduced glomerular capillary endothelial fenestration promote kidney disease in type 2 diabetic nephropathy.

Journal: Kidney international 20121101

Title: Comparison of medium-dose losartan/hydrochlorothiazide and maximal-dose angiotensin II receptor blockers in the treatment of Japanese patients with uncontrolled hypertension: the Kobe-CONNECT Study.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20121101

Title: The vitamin D receptor activator paricalcitol prevents fibrosis and diastolic dysfunction in a murine model of pressure overload.

Journal: The Journal of steroid biochemistry and molecular biology 20121101

Title: Microtubules and angiotensin II receptors contribute to modulation of repolarization induced by ventricular pacing.

Journal: Heart rhythm 20121101

Title: Outcome of venom bradykinin potentiating factor on rennin-angiotensin system in irradiated rats.

Journal: International journal of radiation biology 20121101

Title: TGFβ signaling: its role in fibrosis formation and myopathies.

Journal: Current opinion in rheumatology 20121101

Title: Acute ethanol intake induces superoxide anion generation and mitogen-activated protein kinase phosphorylation in rat aorta: a role for angiotensin type 1 receptor.

Journal: Toxicology and applied pharmacology 20121101

Title: eNOS deficiency predisposes podocytes to injury in diabetes.

Journal: Journal of the American Society of Nephrology : JASN 20121101

Title: On the different roles of AT1 and AT2 receptors in stretch-induced changes of connexin43 expression and localisation.

Journal: Pflugers Archiv : European journal of physiology 20121101

Title: A multi-center, double-blind, randomized, parallel group study to evaluate the effects of two different doses of losartan on morbidity and mortality in Chinese patients with symptomatic heart failure intolerant of angiotensin converting enzyme inhibitor treatment.

Journal: Chinese medical journal 20121101

Title: Superoxide anions modulate the effects of angiotensin-(1-7) in the rostral ventrolateral medulla on cardiac sympathetic afferent reflex and sympathetic activity in rats.

Journal: Neuroscience 20121025

Title: Central angiotensin II-induced Alzheimer-like tau phosphorylation in normal rat brains.

Journal: FEBS letters 20121019

Title: β-Arrestin-biased AT1R stimulation promotes cell survival during acute cardiac injury.

Journal: American journal of physiology. Heart and circulatory physiology 20121015

Title: Skimmin, a coumarin, suppresses the streptozotocin-induced diabetic nephropathy in wistar rats.

Journal: European journal of pharmacology 20121005

Title: Advanced glycation end products (AGE) induce the receptor for AGE in the colonic mucosa of azoxymethane-injected Fischer 344 rats fed with a high-linoleic acid and high-glucose diet.

Journal: Journal of gastroenterology 20121001

Title: Regression of ECG-LVH is associated with lower risk of new-onset heart failure and mortality in patients with isolated systolic hypertension; The LIFE study.

Journal: American journal of hypertension 20121001

Title: Angiotensin II increases CTGF expression via MAPKs/TGF-β1/TRAF6 pathway in atrial fibroblasts.

Journal: Experimental cell research 20121001

Title: Losartan, an angiotensin II type 1 receptor blocker, ameliorates cerebral ischemia-reperfusion injury via PI3K/Akt-mediated eNOS phosphorylation.

Journal: Brain research bulletin 20121001

Title: AT1 antagonism and renin inhibition in mice: pivotal role of targeting angiotensin II in chronic kidney disease.

Journal: American journal of physiology. Renal physiology 20121001

Title: Treatment of idiopathic pulmonary fibrosis with losartan: a pilot project.

Journal: Lung 20121001

Title: Angiotensin II-induced mitochondrial reactive oxygen species and peroxiredoxin-3 expression in cardiac fibroblasts.

Journal: Journal of hypertension 20121001

Title: Evaluation of water uptake and mechanical properties of blended polymer films for preparing gas-generated multiple-unit floating drug delivery systems.

Journal: Journal of pharmaceutical sciences 20121001

Title: Regulation of aortic extracellular matrix synthesis via noradrenergic system and angiotensin II in juvenile rats.

Journal: Pharmaceutical biology 20121001

Title: Dysregulated renin-angiotensin-aldosterone system contributes to pulmonary arterial hypertension.

Journal: American journal of respiratory and critical care medicine 20121001

Title: Fraction SX of maitake mushroom favorably influences blood glucose levels and blood pressure in streptozotocin-induced diabetic rats.

Journal: Journal of medicinal food 20121001

Title: Similarities and differences between effects of angiotensin III and angiotensin II on human prostate cancer cell migration and proliferation.

Journal: Peptides 20121001

Title: Renal protection of losartan 50 mg in normotensive Chinese patients with nondiabetic chronic kidney disease.

Journal: Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20121001

Title: Antihypertensive effects of olmesartan compared with other angiotensin receptor blockers: a meta-analysis.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20121001

Title: Angiotensin II promotes iron accumulation and depresses PGI₂ and NO synthesis in endothelial cells: effects of losartan and propranolol analogs.

Journal: Canadian journal of physiology and pharmacology 20121001

Title: [AII antagonists (candesartan and irbesartan) in the treatment of cardiovascular diseases].

Journal: Vnitrni lekarstvi 20121001

Title: Apocynum venetum leaf extract, an antihypertensive herb, inhibits rat aortic contraction induced by angiotensin II: a nitric oxide and superoxide connection.

Journal: Journal of ethnopharmacology 20120928

Title: A primary culture of distal convoluted tubules expressing functional thiazide-sensitive NaCl transport.

Journal: American journal of physiology. Renal physiology 20120915

Title: Vitamin D receptor activation and downregulation of renin-angiotensin system attenuate morphine-induced T cell apoptosis.

Journal: American journal of physiology. Cell physiology 20120915

Title: Characterization of the in vivo antiplatelet activity of the antihypertensive agent losartan.

Journal: Journal of cardiovascular pharmacology and therapeutics 20120901

Title: Cardiovascular actions of angiotensin-(1-12) in the hypothalamic paraventricular nucleus of the rat are mediated via angiotensin II.

Journal: Experimental physiology 20120901

Title: The effect of losartan and carvedilol on renal haemodynamics and altered metabolism in fructose-fed Sprague-Dawley rats.

Journal: Journal of physiology and biochemistry 20120901

Title: Combined treatment with a dipeptidyl peptidase-IV inhibitor (sitagliptin) and an angiotensin II type 1 receptor blocker (losartan) promotes islet regeneration via enhanced differentiation of pancreatic progenitor cells.

Journal: Diabetes, obesity & metabolism 20120901

Title: Characterization of Angiotensin-(1-7) effects on the cardiovascular system in an experimental model of type-1 diabetes.

Journal: Pharmacological research 20120901

Title: Rosiglitazone inhibits angiotensin II-induced C-reactive protein production in human aortic endothelial cells through regulating AT(1)-ROS-MAPK signal pathway.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20120901

Title: Contrasting hemodynamic mechanisms of losartan- vs. atenolol-based antihypertensive treatment: a LIFE study.

Journal: American journal of hypertension 20120901

Title: Effects of CYP2C9*1/*3 and *1/*13 on the pharmacokinetics of losartan and its active metabolite E-3174.

Journal: International journal of clinical pharmacology and therapeutics 20120901

Title: Perinatal nicotine exposure increases vulnerability of hypoxic-ischemic brain injury in neonatal rats: role of angiotensin II receptors.

Journal: Stroke 20120901

Title: AT1a receptor signaling is required for basal and water deprivation-induced urine concentration in AT1a receptor-deficient mice.

Journal: American journal of physiology. Renal physiology 20120901

Title: Captopril intake decreases body weight gain via angiotensin-(1-7).

Journal: Peptides 20120901

Title: Efficacy and effect on plasma B-type natriuretic peptide concentration of losartan-hydrochlorothiazide for hypertension uncontrolled by losartan-based therapy: subanalysis of a Multicentre Prospective Observational Study.

Journal: Arzneimittel-Forschung 20120901

Title: Angiotensin II type 2 receptor-mediated inhibition of NaCl absorption is blunted in thick ascending limbs from Dahl salt-sensitive rats.

Journal: Hypertension (Dallas, Tex. : 1979) 20120901

Title: The discovery of new potent non-peptide Angiotensin II AT1 receptor blockers: a concise synthesis, molecular docking studies and biological evaluation of N-substituted 5-butylimidazole derivatives.

Journal: European journal of medicinal chemistry 20120901

Title: A combination of vitamin C and losartan for cisplatin-induced nephrotoxicity in rats.

Journal: Iranian journal of kidney diseases 20120901

Title: Counteraction between angiotensin II and angiotensin-(1-7) via activating angiotensin type I and Mas receptor on rat renal mesangial cells.

Journal: Regulatory peptides 20120820

Title: Resveratrol attenuates angiotensin II-induced senescence of vascular smooth muscle cells.

Journal: Regulatory peptides 20120820

Title: Angiotensin-(3-4) counteracts the Angiotensin II inhibitory action on renal Ca2+-ATPase through a cAMP/PKA pathway.

Journal: Regulatory peptides 20120820

Title: Salt-induced downregulation of renal aquaporins is prevented by losartan.

Journal: Regulatory peptides 20120820

Title: HIV-induced kidney cell injury: role of ROS-induced downregulated vitamin D receptor.

Journal: American journal of physiology. Renal physiology 20120815

Title: Exercise training normalizes enhanced sympathetic activation from the paraventricular nucleus in chronic heart failure: role of angiotensin II.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20120815

Title: IL-17-mediated oxidative stress is an important stimulator of AT1-AA and hypertension during pregnancy.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20120815

Title: Effect of AT1 receptor blockade on intermittent hypoxia-induced endothelial dysfunction.

Journal: Respiratory physiology & neurobiology 20120815

Title: Differential effects of late-life initiation of low-dose enalapril and losartan on diastolic function in senescent Fischer 344 x Brown Norway male rats.

Journal: Age (Dordrecht, Netherlands) 20120801

Title: Cardiac remodeling and function following exercise and angiotensin II receptor antagonism.

Journal: European journal of applied physiology 20120801

Title: Renin activates PI3K-Akt-eNOS signalling through the angiotensin AT₁ and Mas receptors to modulate central blood pressure control in the nucleus tractus solitarii.

Journal: British journal of pharmacology 20120801

Title: Modulation of thiopental-induced vascular relaxation and contraction by perivascular adipose tissue and endothelium.

Journal: British journal of anaesthesia 20120801

Title: Losartan attenuates human monocyte-derived dendritic cell immune maturation via downregulation of lectin-like oxidized low-density lipoprotein receptor-1.

Journal: Journal of cardiovascular pharmacology 20120801

Title: Aspirin downregulates angiotensin type 1 receptor transcription implications in capillary formation from endothelial cells.

Journal: Journal of cardiovascular pharmacology 20120801

Title: Impact of serum uric acid on renal function and cardiovascular events in hypertensive patients treated with losartan.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20120801

Title: A novel method for the determination of the site of glucuronidation by ion mobility spectrometry-mass spectrometry.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20120801

Title: Angiotensin II enhances AT1-Nox1 binding and stimulates arterial smooth muscle cell migration and proliferation through AT1, Nox1, and interleukin-18.

Journal: American journal of physiology. Heart and circulatory physiology 20120801

Title: Biased agonism of the angiotensin II type 1 receptor.

Journal: Mini reviews in medicinal chemistry 20120801

Title: Induction of angiotensin-converting enzyme and activation of the renin-angiotensin system contribute to 20-hydroxyeicosatetraenoic acid-mediated endothelial dysfunction.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20120801

Title: Treatment of diastolic dysfunction in hypertension.

Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD 20120801

Title: Synthesis and biological evaluation of 4'-[(benzimidazole-1-yl)methyl]biphenyl-2-sulfonamide derivatives as dual angiotensin II/endothelin A receptor antagonists.

Journal: Bioorganic & medicinal chemistry 20120801

Title: Association of pulse pressure with new-onset atrial fibrillation in patients with hypertension and left ventricular hypertrophy: the Losartan Intervention For Endpoint (LIFE) reduction in hypertension study.

Journal: Hypertension (Dallas, Tex. : 1979) 20120801

Title: Liquid chromatography-mass spectrometric determination of losartan and its active metabolite on dried blood spots.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120801

Title: Implication of multiple signaling pathways in the regulation of angiotensin II induced enhanced expression of Giα proteins in vascular smooth muscle cells.

Journal: Canadian journal of physiology and pharmacology 20120801

Title: Role of chymase in diabetic nephropathy.

Journal: Experimental biology and medicine (Maywood, N.J.) 20120801

Title: Simvastatin and losartan differentially and synergistically inhibit atherosclerosis in apolipoprotein e(-/-) mice.

Journal: Korean circulation journal 20120801

Title: Losartan vs candesartan for heart failure.

Journal: JAMA 20120725

Title: A brain leptin-renin angiotensin system interaction in the regulation of sympathetic nerve activity.

Journal: American journal of physiology. Heart and circulatory physiology 20120715

Title: Design, synthesis and biological activity of 6-substituted carbamoyl benzimidazoles as new nonpeptidic angiotensin II AT₁ receptor antagonists.

Journal: Bioorganic & medicinal chemistry 20120715

Title: Plasma fibrin clot properties in arterial hypertension and their modification by antihypertensive medication.

Journal: Thrombosis research 20120701

Title: Losartan prevents the development of the pro-inflammatory monocytes CD14+CD16+ in haemodialysis patients.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120701

Title: Effects of angiotensin receptor blockers on endothelial nitric oxide release: the role of eNOS variants.

Journal: British journal of clinical pharmacology 20120701

Title: Search for the molecular basis of ultra-rapid CYP2C9-catalysed metabolism: relationship between SNP IVS8-109A>T and the losartan metabolism phenotype in Swedes.

Journal: European journal of clinical pharmacology 20120701

Title: Combination therapy with an angiotensin II receptor blocker and an HMG-CoA reductase inhibitor in experimental subtotal nephrectomy.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120701

Title: Angiotensin III induces c-Jun N-terminal kinase leading to proliferation of rat astrocytes.

Journal: Neurochemical research 20120701

Title: Impaired sodium excretion and salt-sensitive hypertension in corin-deficient mice.

Journal: Kidney international 20120701

Title: Angiotensin II type 2 receptor-dependent increase in nitric oxide synthase activity in the endothelium of db/db mice is mediated via a MEK pathway.

Journal: Pharmacological research 20120701

Title: Angiotensin II type I receptor and miR-155 in endometrial cancers: synergistic antiproliferative effects of anti-miR-155 and losartan on endometrial cancer cells.

Journal: Gynecologic oncology 20120701

Title: The relationship between lung inflammation and cardiovascular disease.

Journal: American journal of respiratory and critical care medicine 20120701

Title: The velocity of antihypertensive effect of losartan/hydrochlorothiazide and angiotensin II receptor blocker.

Journal: Journal of hypertension 20120701

Title: Involvement of enhanced cardiac sympathetic afferent reflex in sympathetic activation in early stage of diabetes.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20120701

Title: Angiotensin AT(1) receptor inhibition-induced apoptosis by RhoA GTPase activation and pERK1/2 signaling pathways in neonatal obstructive nephropathy.

Journal: Histology and histopathology 20120701

Title: Effect of phosphatidylinositol 3-kinase-γ inhibitor CAY10505 in hypertension, and its associated vascular endothelium dysfunction in rats.

Journal: Canadian journal of physiology and pharmacology 20120701

Title: Dose-modifying factor for captopril for mitigation of radiation injury to normal lung.

Journal: Journal of radiation research 20120701

Title: [Inhibitory effect of losartan on prostatic hyperplasia in spontaneous hypertension rats and its pathophysiological mechanism].

Journal: Zhonghua nan ke xue = National journal of andrology 20120701

Title: Telmisartan inhibits vascular dysfunction and inflammation via activation of peroxisome proliferator-activated receptor-γ in subtotal nephrectomized rat.

Journal: European journal of pharmacology 20120615

Title: Combination exenatide-sitagliptin therapy used with glipizide in a patient with type 2 diabetes mellitus.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20120615

Title: The Ghent Marfan Trial--a randomized, double-blind placebo controlled trial with losartan in Marfan patients treated with β-blockers.

Journal: International journal of cardiology 20120614

Title: MMP-2 regulates Erk1/2 phosphorylation and aortic dilatation in Marfan syndrome.

Journal: Circulation research 20120608

Title: Prevention of type 2 diabetes and its complications in developing countries: a review.

Journal: International journal of behavioral medicine 20120601

Title: Angiotensin II type 1 (AT-1) receptor inhibition partially prevents the urodynamic and detrusor changes associated with bladder outlet obstruction: a mouse model.

Journal: BJU international 20120601

Title: Inhibition of the renin-angiotensin system downregulates tissue factor and vascular endothelial growth factor in human breast carcinoma cells.

Journal: Thrombosis research 20120601

Title: The relationship of electrocardiographic left ventricular hypertrophy to decreased serum potassium.

Journal: Blood pressure 20120601

Title: Impact of glycaemic control on the effect of direct renin inhibition in the AVOID study.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20120601

Title: Influence of diabetes on efficacy of aliskiren, losartan or both on left ventricular mass regression.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20120601

Title: Association of heart failure hospitalizations with combined electrocardiography and echocardiography criteria for left ventricular hypertrophy.

Journal: American journal of hypertension 20120601

Title: Angiotensin converting enzyme 2 contributes to sex differences in the development of obesity hypertension in C57BL/6 mice.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20120601

Title: Comparison of the efficacy and safety of fixed-dose amlodipine/losartan and losartan in hypertensive patients inadequately controlled with losartan: a randomized, double-blind, multicenter study.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20120601

Title: Losartan versus atenolol-based antihypertensive treatment reduces cardiovascular events especially well in elderly patients: the Losartan Intervention For Endpoint reduction in hypertension (LIFE) study.

Journal: Journal of hypertension 20120601

Title: Temporal alterations in vascular angiotensin receptors and vasomotor responses in offspring of protein-restricted rat dams.

Journal: American journal of obstetrics and gynecology 20120601

Title: The second sodium pump: from the function to the gene.

Journal: Pflugers Archiv : European journal of physiology 20120601

Title: Aldosterone does not require angiotensin II to activate NCC through a WNK4-SPAK-dependent pathway.

Journal: Pflugers Archiv : European journal of physiology 20120601

Title: Oral aripiprazole-induced severe hypoglycemia.

Journal: Therapeutic drug monitoring 20120601

Title: The role of AT1 receptor-mediated reproductive function in renovascular hypertension in male rats.

Journal: Hormones and behavior 20120601

Title: Clinical and molecular approaches to individualize antihypertensive drug therapy.

Journal: Annals of medicine 20120601

Title: Efficacy/safety of olmesartan medoxomil versus losartan potassium in naïve versus previously treated subjects with hypertension.

Journal: Advances in therapy 20120601

Title: A new transgenic rat model overexpressing the angiotensin II type 2 receptor provides evidence for inhibition of cell proliferation in the outer adrenal cortex.

Journal: American journal of physiology. Endocrinology and metabolism 20120515

Title: Angiotensin AT1 receptor-associated protein Arap1 in the kidney vasculature is suppressed by angiotensin II.

Journal: American journal of physiology. Renal physiology 20120515

Title: Des-aspartate-angiotensin I exerts antiviral effects and attenuates ICAM-1 formation in rhinovirus-infected epithelial cells.

Journal: European journal of pharmacology 20120515

Title: Effects of proangiotensin-12 infused continuously over 14 days in conscious rats.

Journal: European journal of pharmacology 20120515

Title: Activating autoantibodies to the angiotensin II type I receptor play an important role in mediating hypertension in response to adoptive transfer of CD4+ T lymphocytes from placental ischemic rats.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20120515

Title: Role of angiotensin II in the brain inflammatory events during experimental diabetes in rats.

Journal: Brain research 20120509

Title: Angiotensin II induces protein overexpression of hyperpolarization-activated cyclic nucleotide-gated channels in primary cultured nodose neurons.

Journal: Neuroscience letters 20120502

Title: Animal models of cardiorenal syndrome: a review.

Journal: Heart failure reviews 20120501

Title: Myosin binding protein C: implications for signal-transduction.

Journal: Journal of muscle research and cell motility 20120501

Title: LPS-stimulated cytokine production in type I cells is modulated by the renin-angiotensin system.

Journal: American journal of respiratory cell and molecular biology 20120501

Title: Pierson syndrome in an adolescent girl with nephrotic range proteinuria but a normal GFR.

Journal: Pediatric nephrology (Berlin, Germany) 20120501

Title: Comparison of the efficacy and safety of azilsartan with that of candesartan cilexetil in Japanese patients with grade I-II essential hypertension: a randomized, double-blind clinical study.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20120501

Title: AT1 receptor blockade delays postlactational mammary gland involution: a novel role for the renin angiotensin system.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20120501

Title: Early treatment with olmesartan prevents juxtamedullary glomerular podocyte injury and the onset of microalbuminuria in type 2 diabetic rats.

Journal: American journal of hypertension 20120501

Title: RhoA guanine exchange factor expression profile in arteries: evidence for a Rho kinase-dependent negative feedback in angiotensin II-dependent hypertension.

Journal: American journal of physiology. Cell physiology 20120501

Title: Angiotensin II type 2 receptor-coupled nitric oxide production modulates free radical availability and voltage-gated Ca2+ currents in NTS neurons.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20120501

Title: Emphysema in an adult with galactosialidosis linked to a defect in primary elastic fiber assembly.

Journal: Molecular genetics and metabolism 20120501

Title: An initial reduction in serum uric acid during angiotensin receptor blocker treatment is associated with cardiovascular protection: a post-hoc analysis of the RENAAL and IDNT trials.

Journal: Journal of hypertension 20120501

Title: Angiotensin-(1-7) administration reduces oxidative stress in diabetic bone marrow.

Journal: Endocrinology 20120501

Title: Peroxisome proliferator-activated receptor-γ activation with angiotensin II type 1 receptor blockade is pivotal for the prevention of blood-brain barrier impairment and cognitive decline in type 2 diabetic mice.

Journal: Hypertension (Dallas, Tex. : 1979) 20120501

Title: High-sensitivity liquid chromatography-tandem mass spectrometry for the simultaneous determination of five drugs and their cytochrome P450-specific probe metabolites in human plasma.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120501

Title: Circadian variations in exsorptive transport: in situ intestinal perfusion data and in vivo relevance.

Journal: Chronobiology international 20120501

Title: Losartan, a therapeutic candidate in congenital muscular dystrophy: studies in the dy(2J) /dy(2J) mouse.

Journal: Annals of neurology 20120501

Title: Bioequivalence study of two losartan tablet formulations with special emphasis on cardiac safety.

Journal: International journal of clinical pharmacology and therapeutics 20120501

Title: Antihypertensive drugs in patients treated with antiretrovirals.

Journal: The Annals of pharmacotherapy 20120501

Title: [Effects of ligustrazine on the mitochondrial structure and functions in the process myocardial hypertrophy].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20120501

Title: Efficacy/safety of olmesartan medoxomil versus losartan potassium in patients by stage 1 or 2 hypertension.

Journal: Postgraduate medicine 20120501

Title: Angiotensin II plays a critical role in alcohol-induced cardiac nitrative damage, cell death, remodeling, and cardiomyopathy in a protein kinase C/nicotinamide adenine dinucleotide phosphate oxidase-dependent manner.

Journal: Journal of the American College of Cardiology 20120417

Title: Synthesis and biological evaluation of novel potent angiotensin II receptor antagonists with anti-hypertension effect.

Journal: Bioorganic & medicinal chemistry 20120415

Title: Losartan's affinity to fluid bilayers modulates lipid-cholesterol interactions.

Journal: Physical chemistry chemical physics : PCCP 20120414

Title: Association of treatment with losartan vs candesartan and mortality among patients with heart failure.

Journal: JAMA 20120411

Title: Decreased anandamide transporter activity and calcitonin gene-related peptide production in spontaneously hypertensive rats: role of angiotensin II.

Journal: European journal of pharmacology 20120405

Title: Angiotensin-II induced nitric oxide production during buffalo sperm capacitation and acrosome reaction.

Journal: Research in veterinary science 20120401

Title: Pharmacokinetics of losartan and its active carboxylic acid metabolite E-3174 in five ethnic populations of China.

Journal: Journal of clinical pharmacy and therapeutics 20120401

Title: Racial differences in sudden cardiac death among hypertensive patients during antihypertensive therapy: the LIFE study.

Journal: Heart rhythm 20120401

Title: The protective effect of losartan in the nephropathy of the diabetic rat includes the control of monoamine oxidase type A activity.

Journal: Pharmacological research 20120401

Title: Antihypertensive effect of a fixed-dose combination of losartan/hydrochlorothiazide in patients with uncontrolled hypertension: a multicenter study.

Journal: Clinical and experimental nephrology 20120401

Title: Revelation on the potency of α(1) -blockers - parallel blockade of angiotensin II receptor: a new finding.

Journal: Pharmaceutical biology 20120401

Title: Dual RAS blockade normalizes angiotensin-converting enzyme-2 expression and prevents hypertension and tubular apoptosis in Akita angiotensinogen-transgenic mice.

Journal: American journal of physiology. Renal physiology 20120401

Title: Exposure of luminal membranes of LLC-PK1 cells to ANG II induces dimerization of AT1/AT2 receptors to activate SERCA and to promote Ca2+ mobilization.

Journal: American journal of physiology. Renal physiology 20120401

Title: Angiotensin II induces tumor necrosis factor-α expression and release from cultured human podocytes.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20120401

Title: Oral simvastatin reduces the hypertensive response to air-jet stress.

Journal: Clinical and experimental pharmacology & physiology 20120401

Title: Diabetes and hypertension: is there a common metabolic pathway?

Journal: Current atherosclerosis reports 20120401

Title: Receptor activator of nuclear factor-κB ligand is a novel inducer of myocardial inflammation.

Journal: Cardiovascular research 20120401

Title: New losartan-hydrocaffeic acid hybrids as antihypertensive-antioxidant dual drugs: Ester, amide and amine linkers.

Journal: European journal of medicinal chemistry 20120401

Title: Impact of lower achieved blood pressure on outcomes in hypertensive patients.

Journal: Journal of hypertension 20120401

Title: Occipital nerve block is effective in craniofacial neuralgias but not in idiopathic persistent facial pain.

Journal: The journal of headache and pain 20120401

Title: Is losartan the drug for all seasons?

Journal: Current opinion in pharmacology 20120401

Title: Regulation of muscle microcirculation in health and diabetes.

Journal: Diabetes & metabolism journal 20120401

Title: Effect of eplerenone, a selective aldosterone blocker, on the development of diabetic nephropathy in type 2 diabetic rats.

Journal: Diabetes & metabolism journal 20120401

Title: A case of near total aortic replacement in an adolescent with loeys-dietz syndrome.

Journal: Korean circulation journal 20120401

Title: Effects of weight change on clinical outcomes in overweight and obese patients with acute myocardial infarction who underwent successful percutaneous coronary intervention.

Journal: Chonnam medical journal 20120401

Title: Analysis of cytotoxicity induced by proinflammatory cytokines in the human alveolar epithelial cell line A549.

Journal: Bioscience trends 20120401

Title: The effect of leflunomide on cold and vibratory sensation in patients with rheumatoid arthritis.

Journal: Annals of rehabilitation medicine 20120401

Title: Angiotensin II stimulates epithelial sodium channels in the cortical collecting duct of the rat kidney.

Journal: American journal of physiology. Renal physiology 20120315

Title: Angiotensin-(1-7)-induced activation of ERK1/2 is cAMP/protein kinase A-dependent in glomerular mesangial cells.

Journal: American journal of physiology. Renal physiology 20120315

Title: Angiotensin AT1 receptor blockers suppress oxidized low-density lipoprotein-derived formation of foam cells.

Journal: European journal of pharmacology 20120315

Title: Aspirin suppresses cardiac fibroblast proliferation and collagen formation through downregulation of angiotensin type 1 receptor transcription.

Journal: Toxicology and applied pharmacology 20120315

Title: A re-appraisal of volume status and renal function impairment in chronic heart failure: combined effects of pre-renal failure and venous congestion on renal function.

Journal: Heart failure reviews 20120301

Title: New roles for renin and prorenin in heart failure and cardiorenal crosstalk.

Journal: Heart failure reviews 20120301

Title: Physiological regulation of extracellular matrix collagen and elastin in the arterial wall of rats by noradrenergic tone and angiotensin II.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20120301

Title: Effect of fixed-dose losartan/hydrochlorothiazide on brain natriuretic peptide in patients with hypertension.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20120301

Title: Comparative effectiveness of individual angiotensin receptor blockers on risk of mortality in patients with chronic heart failure.

Journal: Pharmacoepidemiology and drug safety 20120301

Title: Impact of aliskiren treatment on urinary aldosterone levels in patients with type 2 diabetes and nephropathy: an AVOID substudy.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20120301

Title: Abilities of candesartan and other AT(1) receptor blockers to impair angiotensin II-induced AT(1) receptor activation after wash-out.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20120301

Title: Elevated N-terminal pro-brain natriuretic peptide levels predict an enhanced anti-hypertensive and anti-proteinuric benefit of dietary sodium restriction and diuretics, but not angiotensin receptor blockade, in proteinuric renal patients.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120301

Title: (Pro)renin receptor: another member of the system controlled by angiotensin II?

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20120301

Title: Comparative effects of different modes of renin angiotensin system inhibition on hypercholesterolaemia-induced atherosclerosis.

Journal: British journal of pharmacology 20120301

Title: Effects of losartan on whole body, skeletal muscle and vascular insulin responses in obesity/insulin resistance without hypertension.

Journal: Diabetes, obesity & metabolism 20120301

Title: Physiological regulation of MMPs and tPA/PAI in the arterial wall of rats by noradrenergic tone and angiotensin II.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20120301

Title: Qiliqiangxin inhibits the development of cardiac hypertrophy, remodeling, and dysfunction during 4 weeks of pressure overload in mice.

Journal: Journal of cardiovascular pharmacology 20120301

Title: Influence of ramiprilat and losartan on ischemia reperfusion injury in rat hearts.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20120301

Title: Effect of changing heart rate during treatment of hypertension on incidence of heart failure.

Journal: The American journal of cardiology 20120301

Title: Role of angiotensin and endothelin in testicular ischemia reperfusion injury.

Journal: International journal of urology : official journal of the Japanese Urological Association 20120301

Title: Enalapril reverses high-fat diet-induced alterations in cytochrome P450-mediated eicosanoid metabolism.

Journal: American journal of physiology. Endocrinology and metabolism 20120301

Title: Antihypertensive efficacy of the losartan/hydrochlorothiazide combination and its effect on plasma B-type natriuretic peptide in hypertensive patients uncontrolled by angiotensin II type 1 receptor antagonist-based therapy: a multicentre prospective observational study.

Journal: Clinical drug investigation 20120301

Title: Reno-protective effects of renin-angiotensin system blockade in type 2 diabetic patients: a systematic review and network meta-analysis.

Journal: Diabetologia 20120301

Title: Binding of losartan to angiotensin AT1 receptors increases dopamine D1 receptor activation.

Journal: Journal of the American Society of Nephrology : JASN 20120301

Title: Sympathetic signatures of cardiovascular disease: a blueprint for development of targeted sympathetic ablation therapies.

Journal: Hypertension (Dallas, Tex. : 1979) 20120301

Title: Central angiotensin type 1 receptor blockade decreases cardiac but not renal sympathetic nerve activity in heart failure.

Journal: Hypertension (Dallas, Tex. : 1979) 20120301

Title: Tannic acid down-regulates the angiotensin type 1 receptor through a MAPK-dependent mechanism.

Journal: Molecular endocrinology (Baltimore, Md.) 20120301

Title: Automated data extraction--a feasible way to construct patient registers of primary care utilization.

Journal: Upsala journal of medical sciences 20120301

Title: Have we observed the implications of the acute fall in eGFR during treatment with losartan?

Journal: Kidney international 20120301

Title: Pre-renal success.

Journal: Kidney international 20120301

Title: Angiotensin II receptor antagonist reduces subsequent uterine arterial dysfunction in pregnant offspring of protein-restricted rat dams.

Journal: The journal of obstetrics and gynaecology research 20120301

Title: Efficacy and tolerability of fimasartan, a new angiotensin receptor blocker, compared with losartan (50/100 mg): a 12-week, phase III, multicenter, prospective, randomized, double-blind, parallel-group, dose escalation clinical trial with an optional 12-week extension phase in adult Korean patients with mild-to-moderate hypertension.

Journal: Clinical therapeutics 20120301

Title: The role of ARBs alone or with HCTZ in the treatment of hypertension and prevention of cardiovascular and renal complications.

Journal: Postgraduate medicine 20120301

Title: Biological approaches to improve skeletal muscle healing after injury and disease.

Journal: Birth defects research. Part C, Embryo today : reviews 20120301

Title: Effects of Losartan vs. Enalapril on the Markers of Metabolic Syndrome.

Journal: Oman medical journal 20120301

Title: Subtle issues in model specification and estimation of marginal structural models.

Journal: Pharmacoepidemiology and drug safety 20120301

Title: Losartan potassium loaded sustained release matrix tablets: Influence of various hydrophilic and hydrophobic polymers on drug release behaviour.

Journal: Journal of pharmacy & bioallied sciences 20120301

Title: Angiotensin-converting enzyme-2 overexpression improves left ventricular remodeling and function in a rat model of diabetic cardiomyopathy.

Journal: Journal of the American College of Cardiology 20120221

Title: Role of angiotensin II-mediated AMPK inactivation on obesity-related salt-sensitive hypertension.

Journal: Biochemical and biophysical research communications 20120217

Title: Median preoptic nucleus and subfornical organ drive renal sympathetic nerve activity via a glutamatergic mechanism within the paraventricular nucleus.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20120215

Title: Synthesis and antihypertensive activity of pyrimidin-4(3H)-one derivatives as losartan analogue for new angiotensin II receptor type 1 (AT1) antagonists.

Journal: Bioorganic & medicinal chemistry letters 20120215

Title: Aliskiren combined with losartan in immunoglobulin A nephropathy: an open-labeled pilot study.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120201

Title: Prenatal complex congenital heart disease with Loeys-Dietz syndrome.

Journal: Cardiology in the young 20120201

Title: Effect of angiotensin receptor blockade on insulin sensitivity and endothelial function in abdominally obese hypertensive patients with impaired fasting glucose.

Journal: Clinical science (London, England : 1979) 20120201

Title: Repeated administration of berberine inhibits cytochromes P450 in humans.

Journal: European journal of clinical pharmacology 20120201

Title: Antihypertensive effects and safety of eprosartan: a meta-analysis of randomized controlled trials.

Journal: European journal of clinical pharmacology 20120201

Title: Losartan exerts no protective effects against acute pulmonary embolism-induced hemodynamic changes.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20120201

Title: Cerebral microvascular inflammation in DOCA salt-induced hypertension: role of angiotensin II and mitochondrial superoxide.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20120201

Title: Angiotensin II induces nephrin dephosphorylation and podocyte injury: role of caveolin-1.

Journal: Cellular signalling 20120201

Title: Plasma and tissue concentrations of proangiotensin-12 in rats treated with inhibitors of the renin-angiotensin system.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20120201

Title: Losartan inhibits conventional dendritic cell maturation and Th1 and Th17 polarization responses: Νovel mechanisms of preventive effects on lipopolysaccharide-induced acute lung injury.

Journal: International journal of molecular medicine 20120201

Title: Impact of alcohol habits and smoking on the risk of new-onset atrial fibrillation in hypertensive patients with ECG left ventricular hypertrophy: the LIFE study.

Journal: Blood pressure 20120201

Title: Modulation of renal superoxide dismutase by telmisartan therapy in C57BL/6-Ins2(Akita) diabetic mice.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20120201

Title: Co-administration of haloperidol and drugs affecting the angiotensin pathway: effect on the extrapyramidal system.

Journal: Toxicology mechanisms and methods 20120201

Title: Effects of losartan and amlodipine alone or combined with simvastatin in hypertensive patients with nonalcoholic hepatic steatosis.

Journal: European journal of gastroenterology & hepatology 20120201

Title: Aldosterone-induced brain MAPK signaling and sympathetic excitation are angiotensin II type-1 receptor dependent.

Journal: American journal of physiology. Heart and circulatory physiology 20120201

Title: Regulation of peroxisome proliferator-activated receptor-γ by angiotensin II via transforming growth factor-β1-activated p38 mitogen-activated protein kinase in aortic smooth muscle cells.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20120201

Title: Angiotensin type 2 receptor agonist compound 21 reduces vascular injury and myocardial fibrosis in stroke-prone spontaneously hypertensive rats.

Journal: Hypertension (Dallas, Tex. : 1979) 20120201

Title: Mineralocorticoid receptor blocker eplerenone improves endothelial function and inhibits Rho-associated kinase activity in patients with hypertension.

Journal: Clinical pharmacology and therapeutics 20120201

Title: Evaluation of the dose-response relationship of amlodipine and losartan combination in patients with essential hypertension: an 8-week, randomized, double-blind, factorial, phase II, multicenter study.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20120201

Title: The therapeutic tradeoff between the adverse impacts of a lower GFR and long-term renal protection.

Journal: Kidney international 20120201

Title: Telmisartan exerts renoprotective actions via peroxisome proliferator-activated receptor-γ/hepatocyte growth factor pathway independent of angiotensin II type 1 receptor blockade.

Journal: Hypertension (Dallas, Tex. : 1979) 20120201

Title: Evidence-based hypertension treatment in patients with diabetes.

Journal: Journal of clinical hypertension (Greenwich, Conn.) 20120201

Title: Assessment of prescribers' knowledge of the cost of medications.

Journal: The Annals of pharmacotherapy 20120201

Title: Reduction of NADPH-oxidase activity ameliorates the cardiovascular phenotype in a mouse model of Williams-Beuren Syndrome.

Journal: PLoS genetics 20120201

Title: The Williams-Beuren Syndrome-a window into genetic variants leading to the development of cardiovascular disease.

Journal: PLoS genetics 20120201

Title: [Perindopril and losartan attenuate intrahepatic Toll-like receptor 4 protein expression in rats with bile duct ligation-induced hepatic fibrosis].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20120201

Title: Severe neutropenia in a renal transplant patient suggesting an interaction between mycophenolate and fenofibrate.

Journal: Current drug safety 20120201

Title: miR-29b participates in early aneurysm development in Marfan syndrome.

Journal: Circulation research 20120120

Title: Prolonged effects of intracerebroventricular angiotensin II on drinking, eating and locomotor behavior in mice.

Journal: Regulatory peptides 20120110

Title: Angiotensin receptor blockade attenuates cigarette smoke-induced lung injury and rescues lung architecture in mice.

Journal: The Journal of clinical investigation 20120103

Title: Losartan enhances the success of myoblast transplantation.

Journal: Cell transplantation 20120101

Title: Angiotensin II mediates urotensin II expression by hypoxia in cultured cardiac fibroblast.

Journal: European journal of clinical investigation 20120101

Title: Angiotensin II receptor blocker pretreatment of rats undergoing sudden renal ablation.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120101

Title: Renin is an angiotensin-independent profibrotic mediator: role in pulmonary fibrosis.

Journal: The European respiratory journal 20120101

Title: Losartan and amlodipine on myocardial structure and function: a prospective, randomized, clinical trial.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20120101

Title: Losartan modulates muscular capillary density and reverses thiazide diuretic-exacerbated insulin resistance in fructose-fed rats.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20120101

Title: Cardioprotective effects of low-dose combination therapy with a statin and an angiotensin receptor blocker in a rat myocardial infarction model.

Journal: Journal of cardiology 20120101

Title: Administration of vitamin E and losartan as prophylaxes in cisplatin-induced nephrotoxicity model in rats.

Journal: Journal of nephrology 20120101

Title: Angiotensin II-dependent persistent podocyte loss from destabilized glomeruli causes progression of end stage kidney disease.

Journal: Kidney international 20120101

Title: Mast cells are required for the development of renal fibrosis in the rodent unilateral ureteral obstruction model.

Journal: American journal of physiology. Renal physiology 20120101

Title: Differential changes of aorta and carotid vasodilation in type 2 diabetic GK and OLETF rats: paradoxical roles of hyperglycemia and insulin.

Journal: Experimental diabetes research 20120101

Title: Anti-hypertensive therapy and insulin sensitivity: regulation through the microcirculation?

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20120101

Title: STK39 variation predicts the ambulatory blood pressure response to losartan in hypertensive men.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20120101

Title: Angiotensin II type 1 receptor antagonist attenuates lung fibrosis in hyperoxia-exposed newborn rats.

Journal: The Journal of pharmacology and experimental therapeutics 20120101

Title: Effects of antihypertensive drugs on specific harmonic indices of the pulse waveform in normotensive Wistar Kyoto rats.

Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20120101

Title: Adding thiazide to a renin-angiotensin blocker improves left ventricular relaxation and improves heart failure in patients with hypertension.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20120101

Title: Interstitial fluid flow and cyclic strain differentially regulate cardiac fibroblast activation via AT1R and TGF-β1.

Journal: Experimental cell research 20120101

Title: Autophagy as a therapeutic target in diabetic nephropathy.

Journal: Experimental diabetes research 20120101

Title: Differential effects of strict blood pressure lowering by losartan/hydrochlorothiazide combination therapy and high-dose amlodipine monotherapy on microalbuminuria: the ALPHABET study.

Journal: Journal of the American Society of Hypertension : JASH 20120101

Title: Angiotensin-(1-7)/Mas axis integrity is required for the expression of object recognition memory.

Journal: Neurobiology of learning and memory 20120101

Title: The pharmacokinetic-pharmacodynamic assessment of the hypotensive effect after coadministration of losartan and hydrochlorothiazide in spontaneously hypertensive rats.

Journal: Drug metabolism and pharmacokinetics 20120101

Title: Cost-effectiveness analysis of valsartan versus losartan and the effect of switching.

Journal: Journal of medical economics 20120101

Title: The effect of the thioether-bridged, stabilized Angiotensin-(1-7) analogue cyclic ang-(1-7) on cardiac remodeling and endothelial function in rats with myocardial infarction.

Journal: International journal of hypertension 20120101

Title: Telmisartan ameliorates lipopolysaccharide-induced innate immune response through peroxisome proliferator-activated receptor-γ activation in human monocytes.

Journal: Journal of hypertension 20120101

Title: Effect of a reduction in uric acid on renal outcomes during losartan treatment: a post hoc analysis of the reduction of end points in noninsulin-dependent diabetes mellitus with the Angiotensin II Antagonist Losartan Trial.

Journal: Hypertension (Dallas, Tex. : 1979) 20120101

Title: Renal microvascular injury in chronic aristolochic acid nephropathy and protective effects of Cozaar.

Journal: Renal failure 20120101

Title: Biosynthetic pathways and the role of the MAS receptor in the effects of Angiotensin-(1-7) in smooth muscles.

Journal: International journal of hypertension 20120101

Title: A Novel Cellular Model to Study Angiotensin II AT2 Receptor Function in Breast Cancer Cells.

Journal: International journal of peptides 20120101

Title: Development of a novel 96-microwell assay with high throughput for determination of olmesartan medoxomil in its tablets.

Journal: Chemistry Central journal 20120101

Title: Losartan inhibits STAT1 activation and protects human glomerular mesangial cells from angiotensin II induced premature senescence.

Journal: Canadian journal of physiology and pharmacology 20120101

Title: Angiotensin receptor blocker and N-acetyl cysteine for reduction of proteinuria in patients with type 2 diabetes mellitus.

Journal: Iranian journal of kidney diseases 20120101

Title: Ramipril-based versus diuretic-based antihypertensive primary treatment in patients with pre-diabetes (ADaPT) study.

Journal: Cardiovascular diabetology 20120101

Title: The effect of combination treatment with aliskiren and blockers of the renin-angiotensin system on hyperkalaemia and acute kidney injury: systematic review and meta-analysis.

Journal: BMJ (Clinical research ed.) 20120101

Title: Effects of continuous erythropoietin receptor activator in sepsis-induced acute kidney injury and multi-organ dysfunction.

Journal: PloS one 20120101

Title: Antihypertensive drugs and risk of incident gout among patients with hypertension: population based case-control study.

Journal: BMJ (Clinical research ed.) 20120101

Title: Lymphoid tissue damage in HIV-1 infection depletes naïve T cells and limits T cell reconstitution after antiretroviral therapy.

Journal: PLoS pathogens 20120101

Title: An economic evaluation of antihypertensive therapies based on clinical trials.

Journal: Clinics (Sao Paulo, Brazil) 20120101

Title: Effect of switching from telmisartan, valsartan, olmesartan, or losartan to candesartan on morning hypertension.

Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20120101

Title: TGFβ signaling and cardiovascular diseases.

Journal: International journal of biological sciences 20120101

Title: Genotype-phenotype analysis of F-helix mutations at the kinase domain of TGFBR2, including a type 2 Marfan syndrome familial study.

Journal: Molecular vision 20120101

Title: Preventive pharmacotherapy in type 2 diabetes mellitus.

Journal: Indian journal of endocrinology and metabolism 20120101

Title: The roles of angiotensin II receptors in the portosystemic collaterals of portal hypertensive and cirrhotic rats.

Journal: Journal of vascular research 20120101

Title: Losartan reduces trinitrobenzene sulphonic acid-induced colorectal fibrosis in rats.

Journal: Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20120101

Title: Effect of losartan, an angiotensin II type 1 receptor antagonist on cardiac autonomic functions of rats during acute and chronic inhibition of nitric oxide synthesis.

Journal: Physiological research 20120101

Title: Pre-treatment with curcumin enhances plasma concentrations of losartan and its metabolite EXP3174 in rats.

Journal: Biological & pharmaceutical bulletin 20120101

Title: Toxicities effects of pharmaceutical, olive mill and textile wastewaters before and after degradation by Pseudomonas putida mt-2.

Journal: Cancer cell international 20120101

Title: Kidney disease and youth onset type 2 diabetes: considerations for the general practitioner.

Journal: International journal of pediatrics 20120101

Title: Protective Role of the ACE2/Ang-(1-9) Axis in Cardiovascular Remodeling.

Journal: International journal of hypertension 20120101

Title: New cardiovascular and pulmonary therapeutic strategies based on the Angiotensin-converting enzyme 2/angiotensin-(1-7)/mas receptor axis.

Journal: International journal of hypertension 20120101

Title: Proteinuria: an ignored marker of inflammation and cardiovascular disease in chronic hemodialysis.

Journal: International journal of nephrology and renovascular disease 20120101

Title: Visual loss after spine surgery.

Journal: Indian journal of orthopaedics 20120101

Title: Extra-renal elimination of uric acid via intestinal efflux transporter BCRP/ABCG2.

Journal: PloS one 20120101

Title: Losartan slows pancreatic tumor progression and extends survival of SPARC-null mice by abrogating aberrant TGFβ activation.

Journal: PloS one 20120101

Title: Involvement of PPAR-γ in the neuroprotective and anti-inflammatory effects of angiotensin type 1 receptor inhibition: effects of the receptor antagonist telmisartan and receptor deletion in a mouse MPTP model of Parkinson's disease.

Journal: Journal of neuroinflammation 20120101

Title: Effects of Losartan vs. Enalapril on the Markers of Metabolic Syndrome.

Journal: Oman medical journal 20120101

Title: Evidence and consequences of the central role of the kidneys in the pathophysiology of sympathetic hyperactivity.

Journal: Frontiers in physiology 20120101

Title: Physician and patient predictors of evidence-based prescribing in heart failure: a multilevel study.

Journal: PloS one 20120101

Title: How full is our antihypertensives pipeline?

Journal: Journal of pharmacology & pharmacotherapeutics 20120101

Title: Secondary metabolites of Cynodon dactylon as an antagonist to angiotensin II type1 receptor: Novel in silico drug targeting approach for diabetic retinopathy.

Journal: Journal of pharmacology & pharmacotherapeutics 20120101

Title: Coronary artery disease in Africa and the Middle East.

Journal: Therapeutics and clinical risk management 20120101

Title: Camurati-Engelmann disease--a rare cause of bone pain.

Journal: Connecticut medicine 20120101

Title: Variability of NT-proBNP and its relationship with inflammatory status in patients with stable essential hypertension: a 2-year follow-up study.

Journal: PloS one 20120101

Title: Skeletal muscle apoptotic signaling predicts thigh muscle volume and gait speed in community-dwelling older persons: an exploratory study.

Journal: PloS one 20120101

Title: NT-proBNP, echocardiographic abnormalities and subclinical coronary artery disease in high risk type 2 diabetic patients.

Journal: Cardiovascular diabetology 20120101

Title: Is there benefit in optimising heart failure treatment in over-80 year-old patients? (HF-80 study): study protocol for a randomized controlled trial.

Journal: Trials 20120101

Title: Differential pharmacology and benefit/risk of azilsartan compared to other sartans.

Journal: Vascular health and risk management 20120101

Title: Genomic research to identify novel pathways in the development of abdominal aortic aneurysm.

Journal: Cardiology research and practice 20120101

Title: Identification of periostin as a critical marker of progression/reversal of hypertensive nephropathy.

Journal: PloS one 20120101

Title: Therapeutic options for the treatment of hypertension in children and adolescents.

Journal: Clinical medicine insights. Circulatory, respiratory and pulmonary medicine 20120101

Title: Delayed mTOR inhibition with low dose of everolimus reduces TGFβ expression, attenuates proteinuria and renal damage in the renal mass reduction model.

Journal: PloS one 20120101

Title: The homeostatic chemokine CCL21 predicts mortality and may play a pathogenic role in heart failure.

Journal: PloS one 20120101

Title: Atrial Remodeling in Pregnant Hypertensive Women: Comparison between Chronic and Gestational Hypertension.

Journal: The open cardiovascular medicine journal 20120101

Title: Effect of combination therapy with the angiotensin receptor blocker losartan plus hydrochlorothiazide on brain perfusion in patients with both hypertension and cerebral hemodynamic impairment due to symptomatic chronic major cerebral artery steno-occlusive disease: a SPECT study.

Journal: Cerebrovascular diseases (Basel, Switzerland) 20120101

Title: Amiloride enhances antigen specific CTL by faciliting HBV DNA vaccine entry into cells.

Journal: PloS one 20120101

Title: Brain-derived neurotrophic factor ameliorates brain stem cardiovascular dysregulation during experimental temporal lobe status epilepticus.

Journal: PloS one 20120101

Title: Does a combination pill of antihypertensive drugs improve medication adherence in Japanese? A randomized controlled trial.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20120101

Title: Smoking and idiopathic pulmonary fibrosis.

Journal: Pulmonary medicine 20120101

Title: Quantitative modeling of the physiology of ascites in portal hypertension.

Journal: BMC gastroenterology 20120101

Title: Nebivolol: impact on cardiac and endothelial function and clinical utility.

Journal: Vascular health and risk management 20120101

Title: [Investigate the effects of compound radix notoginseng on renal interstitial fibrosis and kidney-targeting treatment].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20120101

Title: New treatment options in the management of hypertension: appraising the potential role of azilsartan medoxomil.

Journal: Integrated blood pressure control 20120101

Title: The diabetic heart: too sweet for its own good?

Journal: Cardiology research and practice 20120101

Title: Overexpression of urinary N-domain ACE in chronic kidney dysfunction in Wistar rats.

Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20120101

Title: Insulin resistance promotes early atherosclerosis via increased proinflammatory proteins and oxidative stress in fructose-fed ApoE-KO mice.

Journal: Experimental diabetes research 20120101

Title: Choice of generic antihypertensive drugs for the primary prevention of cardiovascular disease--a cost-effectiveness analysis.

Journal: BMC cardiovascular disorders 20120101

Title: High plasma uric acid concentration: causes and consequences.

Journal: Diabetology & metabolic syndrome 20120101

Title: Mineralocorticoid Receptor Blocker Protects against Podocyte-Dependent Glomerulosclerosis.

Journal: Nephron extra 20120101

Title: Inflammation aggravates disease severity in Marfan syndrome patients.

Journal: PloS one 20120101

Title: Uremic toxins induce kidney fibrosis by activating intrarenal renin-angiotensin-aldosterone system associated epithelial-to-mesenchymal transition.

Journal: PloS one 20120101

Title: Increased fibrosis and interstitial fluid pressure in two different types of syngeneic murine carcinoma grown in integrin β3-subunit deficient mice.

Journal: PloS one 20120101

Title: Comparative effectiveness of antihypertensive medication for primary prevention of cardiovascular disease: systematic review and multiple treatments meta-analysis.

Journal: BMC medicine 20120101

Title: Effects of combined endothelin A receptor and renin-angiotensin system blockade on the course of end-organ damage in 5/6 nephrectomized Ren-2 hypertensive rats.

Journal: Kidney & blood pressure research 20120101

Title: The effect of antihypertensive drugs on endothelial function as assessed by flow-mediated vasodilation in hypertensive patients.

Journal: International journal of vascular medicine 20120101

Title: What is a preferred angiotensin II receptor blocker-based combination therapy for blood pressure control in hypertensive patients with diabetic and non-diabetic renal impairment?

Journal: Cardiovascular diabetology 20120101

Title: Design and evaluation of patches for transdermal delivery of losartan potassium.

Journal: PDA journal of pharmaceutical science and technology 20120101

Title: Angiotensinogen gene transcription in pulmonary fibrosis.

Journal: International journal of peptides 20120101

Title: Influence of Angiotensin II Subtype 2 Receptor (AT(2)R) Antagonist, PD123319, on Cardiovascular Remodelling of Aged Spontaneously Hypertensive Rats during Chronic Angiotensin II Subtype 1 Receptor (AT(1)R) Blockade.

Journal: International journal of hypertension 20120101

Title: Novel intriguing strategies attenuating to sarcopenia.

Journal: Journal of aging research 20120101

Title: Glucoregulatory consequences and cardiorespiratory parameters in rats exposed to chronic-intermittent hypoxia: effects of the duration of exposure and losartan.

Journal: Frontiers in neurology 20120101

Title: Angiotensin converting enzyme 2, Angiotensin-(1-7), and receptor MAS axis in the kidney.

Journal: International journal of hypertension 20120101

Title: Reactive Oxygen Species Modulation of Na/K-ATPase Regulates Fibrosis and Renal Proximal Tubular Sodium Handling.

Journal: International journal of nephrology 20120101

Title: Molecular mechanisms of preeclampsia.

Journal: Journal of pregnancy 20120101

Title: Renin angiotensin system: A novel target for migraine prophylaxis.

Journal: Indian journal of pharmacology 20120101

Title: Unilateral ureteric obstruction: Role of renin angiotensin system blockade on renal recovery: An experimental study.

Journal: Journal of Indian Association of Pediatric Surgeons 20120101

Title: Post-weaning protein malnutrition increases blood pressure and induces endothelial dysfunctions in rats.

Journal: PloS one 20120101

Title: Electrocardiographic left ventricular hypertrophy and outcome in hemodialysis patients.

Journal: PloS one 20120101

Title: Angiotensin receptor blockers and risk of cancer: cohort study among people receiving antihypertensive drugs in UK General Practice Research Database.

Journal: BMJ (Clinical research ed.) 20120101

Title: Long-term effects of aliskiren on blood pressure and the renin-angiotensin-aldosterone system in hypertensive hemodialysis patients.

Journal: International journal of nephrology and renovascular disease 20120101

Title: Emerging drug combinations to optimize renovascular protection and blood pressure goals.

Journal: International journal of nephrology and renovascular disease 20120101

Title: Effects of restricted fructose access on body weight and blood pressure circadian rhythms.

Journal: Experimental diabetes research 20120101

Title: Angiotensin-Converting Enzyme 2 (ACE2) Is a Key Modulator of the Renin Angiotensin System in Health and Disease.

Journal: International journal of peptides 20120101

Title: Angiotensin II facilitates breast cancer cell migration and metastasis.

Journal: PloS one 20120101

Title: Connexins and diabetes.

Journal: Cardiology research and practice 20120101

Title: Renin-Angiotensin system hyperactivation can induce inflammation and retinal neural dysfunction.

Journal: International journal of inflammation 20120101

Title: Promyelocytic leukemia zinc finger protein activates GATA4 transcription and mediates cardiac hypertrophic signaling from angiotensin II receptor 2.

Journal: PloS one 20120101

Title: Activation of thiazide-sensitive co-transport by angiotensin II in the cyp1a1-Ren2 hypertensive rat.

Journal: PloS one 20120101

Title: Cardiovascular magnetic resonance in systemic hypertension.

Journal: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20120101

Title: Mechanisms and biomarkers of apoptosis in liver disease and fibrosis.

Journal: International journal of hepatology 20120101

Title: Simultaneous Analysis of Losartan Potassium, Amlodipine Besylate, and Hydrochlorothiazide in Bulk and in Tablets by High-Performance Thin Layer Chromatography with UV-Absorption Densitometry.

Journal: Journal of analytical methods in chemistry 20120101

Title: Different stability-indicating chromatographic techniques for the determination of netobimin.

Journal: Journal of analytical methods in chemistry 20120101

Title: Sensitive spectrophotometric determination of atenolol in pharmaceutical formulations using bromate-bromide mixture as an eco-friendly brominating agent.

Journal: Journal of analytical methods in chemistry 20120101

Title: Glaucomatous optic nerve head alterations in patients with chronic heart failure.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20120101

Title: Anxiolytic-like effect of losartan injected into amygdala of the acutely stressed rats.

Journal: Pharmacological reports : PR 20120101

Title: The prevalence of immunologic injury in renal allograft recipients with de novo proteinuria.

Journal: PloS one 20120101

Title: Hypertension and type 2 diabetes: a cross-sectional study in Morocco (EPIDIAM Study).

Journal: The Pan African medical journal 20120101

Title: Angiotensin II induces angiogenic factors production partly via AT1/JAK2/STAT3/SOCS3 signaling pathway in MHCC97H cells.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101

Title: The role of apelin on the alleviative effect of Angiotensin receptor blocker in unilateral ureteral obstruction-induced renal fibrosis.

Journal: Nephron extra 20120101

Title: Responses to dehydration in the one-humped camel and effects of blocking the renin-angiotensin system.

Journal: PloS one 20120101

Title: Sympathetic activation and baroreflex function during intradialytic hypertensive episodes.

Journal: PloS one 20120101

Title: Can losartan and blood pressure control peri arteriovenous fistula creation ameliorate the early associated left ventricular hypertrophic response a randomised placebo controlled trial.

Journal: BMC research notes 20120101

Title: Telmisartan directly ameliorates the neuronal inflammatory response to IL-1β partly through the JNK/c-Jun and NADPH oxidase pathways.

Journal: Journal of neuroinflammation 20120101

Title: The involvement of angiotensin type 1 and type 2 receptors in estrogen-induced cell proliferation and vascular endothelial growth factor expression in the rat anterior pituitary.

Journal: TheScientificWorldJournal 20120101

Title: Urinary markers of glomerular injury in diabetic nephropathy.

Journal: International journal of nephrology 20120101

Title: Critical evaluation of the efficacy and tolerability of azilsartan.

Journal: Vascular health and risk management 20120101

Title: Use of carvedilol in hypertension: an update.

Journal: Vascular health and risk management 20120101

Title: Clinical efficacy and safety of losartan/hydrochlorothiazide combination therapy.

Journal: Internal medicine (Tokyo, Japan) 20120101

Title: Efficacy and safety of the losartan-hydrochlorothiazide combination tablet in patients with hypertension uncontrolled by angiotensin II receptor antagonist therapy: the Aichi Research on Combination therapy for Hypertension (ARCH) Study.

Journal: Internal medicine (Tokyo, Japan) 20120101

Title: Antioxidants in kidney diseases: the impact of bardoxolone methyl.

Journal: International journal of nephrology 20120101

Title: Activation of EGFR/ERBB2 via pathways involving ERK1/2, P38 MAPK, AKT and FOXO enhances recovery of diabetic hearts from ischemia-reperfusion injury.

Journal: PloS one 20120101

Title: Myocardial contractile dysfunction induced by ovariectomy requires AT1 receptor activation in female rats.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101

Title: Myocardial autophagy after severe burn in rats.

Journal: PloS one 20120101

Title: The role of angiotensin II receptor 1 (AT1) blockade in cisplatin-induced nephrotoxicity in rats: gender-related differences.

Journal: Renal failure 20120101

Title: Randomized Polypill crossover trial in people aged 50 and over.

Journal: PloS one 20120101

Title: Combination of antihypertensive therapy in the elderly, multicenter investigation (CAMUI) trial.

Journal: International heart journal 20120101

Title: (Pro)renin receptor triggers distinct angiotensin II-independent extracellular matrix remodeling and deterioration of cardiac function.

Journal: PloS one 20120101

Title: A low-dose atorvastatin and losartan combination directly improves aortic ring relaxation and diminishes ischaemic-reperfusion injury in isolated rat hearts.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20120101

Title: Effects of combined antihypertensive therapy with losartan/hydrochlorothiazide on uric acid metabolism.

Journal: Internal medicine (Tokyo, Japan) 20120101

Title: Losartan alleviates renal fibrosis by down-regulating HIF-1α and up-regulating MMP-9/TIMP-1 in rats with 5/6 nephrectomy.

Journal: Renal failure 20120101

Title: Adding thiazide to a rennin-angiotensin blocker regimen to improve left ventricular relaxation in diabetes and nondiabetes patients with hypertension.

Journal: Drug design, development and therapy 20120101

Title: Interaction of TNF with angiotensin II contributes to mitochondrial oxidative stress and cardiac damage in rats.

Journal: PloS one 20120101

Title: Vitamin E, Vitamin C, or Losartan Is Not Nephroprotectant against Cisplatin-Induced Nephrotoxicity in Presence of Estrogen in Ovariectomized Rat Model.

Journal: International journal of nephrology 20120101

Title: Effect of angiotensin II type 1 receptor blocker on osteoporotic rat femurs.

Journal: Pharmacological reports : PR 20120101

Title: Losartan-induced coronary artery spasm.

Journal: BMJ case reports 20120101

Title: [Effectiveness and safety of losartan and its combination with hydrochlorothiazide in patients with hypertension: in result study].

Journal: Kardiologiia 20120101

Title: Effect of methanolic fraction of Kalanchoe crenata on metabolic parameters in adriamycin-induced renal impairment in rats.

Journal: Indian journal of pharmacology 20120101

Title: Angiotensin II protects primary rat hepatocytes against bile salt-induced apoptosis.

Journal: PloS one 20120101

Title: Hypotensive effect of atorvastatin in hypertensive patients: the association among flow-mediated dilation, oxidative stress and endothelial dysfunction.

Journal: Archives of medical science : AMS 20111231

Title: IMproving the imPlemEntation of cuRrent guidelines for the mAnagement of major coronary hearT disease rIsk factors by multifactorial interVEntion. The IMPERATIVE renal analysis.

Journal: Archives of medical science : AMS 20111231

Title: Lipids, blood pressure, kidney - what was new in 2011?

Journal: Archives of medical science : AMS 20111231

Title: Synthesis of angiotensin II receptor blockers by means of a catalytic system for C-H activation.

Journal: The Journal of organic chemistry 20111216

Title: [Treatment of gout].

Journal: La Revue de medecine interne 20111201

Title: Chronic angiotensin II infusion modulates angiotensin II type I receptor expression in the subfornical organ and the rostral ventrolateral medulla in hypertensive rats.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20111201

Title: Change in left ventricular geometry during antihypertensive treatment in children with primary hypertension.

Journal: Pediatric nephrology (Berlin, Germany) 20111201

Title: Angiotensin II downregulates catalase expression and activity in vascular adventitial fibroblasts through an AT1R/ERK1/2-dependent pathway.

Journal: Molecular and cellular biochemistry 20111201

Title: Modifying prescribing behaviour of angiotensin receptor blockers by selectively rescinding managerial prior authorization requirements for losartan.

Journal: British journal of clinical pharmacology 20111201

Title: Telomere length and cardiovascular risk in hypertensive patients with left ventricular hypertrophy: the LIFE study.

Journal: Journal of human hypertension 20111201

Title: Proinflammatory role of angiotensin II in a rat nephrosis model induced by adriamycin.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20111201

Title: Intracrine action of angiotensin II in the intact ventricle of the failing heart: angiotensin II changes cardiac excitability from within.

Journal: Molecular and cellular biochemistry 20111201

Title: Suppression of aldosterone mediates regression of left ventricular hypertrophy in patients with hypertension.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20111201

Title: Targeting the renin-angiotensin system: potential beneficial effects of the angiotensin II receptor blockers in patients with nonalcoholic steatohepatitis.

Journal: Hepatology (Baltimore, Md.) 20111201

Title: Liver lipid content is reduced in rat given 7-day administration of angiotensin II.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20111201

Title: Reduction of circulating superoxide dismutase activity in type 2 diabetic patients with microalbuminuria and its modulation by telmisartan therapy.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20111201

Title: Antihypertensive treatment using an angiotensin receptor blocker and a thiazide diuretic improves patients' quality of life: the Saga Challenge Antihypertensive Study (S-CATS).

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20111201

Title: Bitter melon extracts in diabetic and normal rats favorably influence blood glucose and blood pressure regulation.

Journal: Journal of medicinal food 20111201

Title: A two-stage approach to the treatment of hyperuricemia in gout: the 'dirty dish' hypothesis.

Journal: Arthritis and rheumatism 20111201

Title: The loss of muscle mass and sarcopenia: non hormonal intervention.

Journal: Experimental gerontology 20111201

Title: Losartan improves aortic endothelium-dependent relaxation via proline-rich tyrosine kinase 2/Src/Akt pathway in type 2 diabetic Goto-Kakizaki rats.

Journal: American journal of physiology. Heart and circulatory physiology 20111201

Title: Angiotensin II type 1 receptor, but no type 2 receptor, interferes with the insulin-induced nitric oxide production in HUVECs.

Journal: Atherosclerosis 20111201

Title: Angiotensin II-NADPH oxidase-derived superoxide mediates diabetes-attenuated cell excitability of aortic baroreceptor neurons.

Journal: American journal of physiology. Cell physiology 20111201

Title: Prevention and treatment of Schistosoma mansoni-induced liver fibrosis in mice.

Journal: Inflammopharmacology 20111201

Title: ETA and ETB receptors are expressed in vascular adventitial fibroblasts.

Journal: American journal of physiology. Heart and circulatory physiology 20111201

Title: Chronic antagonism of the mineralocorticoid receptor ameliorates hypertension and end organ damage in a rodent model of salt-sensitive hypertension.

Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20111201

Title: The impact of antiproteinuric therapy on the prothrombotic state in patients with overt proteinuria.

Journal: Journal of thrombosis and haemostasis : JTH 20111201

Title: Effects of captopril and angiotensin II receptor blockers (AT1, AT2) on myocardial ischemia-reperfusion induced infarct size.

Journal: Cytokine 20111201

Title: Effects of olmesartan on renal and cardiovascular outcomes in type 2 diabetes with overt nephropathy: a multicentre, randomised, placebo-controlled study.

Journal: Diabetologia 20111201

Title: Acute respiratory distress syndrome leads to reduced ratio of ACE/ACE2 activities and is prevented by angiotensin-(1-7) or an angiotensin II receptor antagonist.

Journal: The Journal of pathology 20111201

Title: Pharmacogenomic strain differences in cardiovascular sensitivity to propofol.

Journal: Anesthesiology 20111201

Title: Renin-angiotensin system inhibitors reduce the progression of mesangioproliferative glomerulonephritis: 10 year follow-up.

Journal: European journal of internal medicine 20111201

Title: Effects of losartan/hydrochlorothiazide on serum uric acid levels and blood pressure in hypertensive patients.

Journal: Nucleosides, nucleotides & nucleic acids 20111201

Title: Cordyceps cicadae extracts ameliorate renal malfunction in a remnant kidney model.

Journal: Journal of Zhejiang University. Science. B 20111201

Title: Comparative efficacy and safety profile of amlodipine 5 mg/losartan 50 mg fixed-dose combination and amlodipine 10 mg monotherapy in hypertensive patients who respond poorly to amlodipine 5 mg monotherapy: an 8-week, multicenter, randomized, double-blind phase III noninferiority study.

Journal: Clinical therapeutics 20111201

Title: Diffuse large cell lymphoma presenting as a sacral mass and lupus anticoagulant.

Journal: The Yale journal of biology and medicine 20111201

Title: Medical reversal: why we must raise the bar before adopting new technologies.

Journal: The Yale journal of biology and medicine 20111201

Title: One size may not fit all: anti-aging therapies and sarcopenia.

Journal: Aging 20111201

Title: Protective measures against ultrafiltration failure in peritoneal dialysis patients.

Journal: Clinics (Sao Paulo, Brazil) 20111201

Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Journal: PLoS computational biology 20111201

Title: Sign of decreased coronary blood flow from ST depression and PVCs during a left lower lobectomy of the lung in a patient with a left internal mammary arterial bypass graft.

Journal: Korean journal of anesthesiology 20111201

Title: Very Late Stent Thrombosis due to Neointimal Rupture After Paclitaxel-Eluting Stent Implantation.

Journal: Korean circulation journal 20111201

Title: NADPH oxidase mediated oxidative stress in hepatic fibrogenesis.

Journal: The Korean journal of hepatology 20111201

Title: Fluorofenidone suppresses epithelial-mesenchymal transition and the expression of connective tissue growth factor via inhibiting TGF-beta/Smads signaling in human proximal tubular epithelial cells.

Journal: Die Pharmazie 20111201

Title: Efficacy and safety of early versus late titration of fixed-dose irbesartan/hydrochlorothiazide: ACTUAL study.

Journal: Blood pressure. Supplement 20111201

Title: Novel pharmacological strategies to prevent aortic complications in Marfan syndrome.

Journal: Journal of geriatric cardiology : JGC 20111201

Title: Structural characteristics of renal glomerular system in ISIAH rats under conditions of chronic stress and preventive hypotensive drug therapy.

Journal: Bulletin of experimental biology and medicine 20111201

Title: Natriorexigenic effect of baclofen is reduced by AT₁ receptor blockade in the lateral parabrachial nucleus.

Journal: Brain research bulletin 20111125

Title: Importance of central AT₁ receptors for sodium intake induced by GABAergic activation of the lateral parabrachial nucleus.

Journal: Neuroscience 20111124

Title: Increased oxidative stress, the renin-angiotensin system, and sympathetic overactivation induce hypertension in kidney androgen-regulated protein transgenic mice.

Journal: Free radical biology & medicine 20111115

Title: Losartan abolishes oxidative stress induced by intermittent hypoxia in humans.

Journal: The Journal of physiology 20111115

Title: Pharmacologic inhibition of the renin-angiotensin system did not attenuate hepatic toxicity induced by carbon tetrachloride in rats.

Journal: Human & experimental toxicology 20111101

Title: [Fibrillary nonamyloid glomerulonephritis: a rare etiology of nephrotic syndrome].

Journal: Nephrologie & therapeutique 20111101

Title: Angiotensin II causes endothelial dysfunction via the GRK2/Akt/eNOS pathway in aortas from a murine type 2 diabetic model.

Journal: Pharmacological research 20111101

Title: High serum potassium levels after using losartan can reflect more severe renal disease.

Journal: Diabetologia 20111101

Title: Enalapril treatment discloses an early role of angiotensin II in inflammation- and oxidative stress-related muscle damage in dystrophic mdx mice.

Journal: Pharmacological research 20111101

Title: Transactivation of epidermal growth factor receptor by enhanced levels of endogenous angiotensin II contributes to the overexpression of Giα proteins in vascular smooth muscle cells from SHR.

Journal: Cellular signalling 20111101

Title: Rosiglitazone versus rosiglitazone and metformin versus rosiglitazone and losartan in the treatment of nonalcoholic steatohepatitis in humans: a 12-month randomized, prospective, open- label trial.

Journal: Hepatology (Baltimore, Md.) 20111101

Title: Electromechanical effects of the direct renin inhibitor (aliskiren) on the pulmonary vein and atrium.

Journal: Basic research in cardiology 20111101

Title: Rationale and current perspective for early rhythm control therapy in atrial fibrillation.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20111101

Title: Fetopathy probably associated to self-medication with a blocker of the renin-angiotensin system.

Journal: Archives of gynecology and obstetrics 20111101

Title: Mechanisms mediating sodium-induced pressor responses in the PVN of Dahl rats.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20111101

Title: Effects of telmisartan and losartan on cardiovascular protection in Japanese hypertensive patients.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20111101

Title: Des-aspartate-angiotensin-I and angiotensin IV improve glucose tolerance and insulin signalling in diet-induced hyperglycaemic mice.

Journal: Biochemical pharmacology 20111101

Title: Downregulation of the antioxidant protein peroxiredoxin 2 contributes to angiotensin II-mediated podocyte apoptosis.

Journal: Kidney international 20111101

Title: The central mechanism underlying hypertension: a review of the roles of sodium ions, epithelial sodium channels, the renin-angiotensin-aldosterone system, oxidative stress and endogenous digitalis in the brain.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20111101

Title: Brain AT1 receptor activates the sympathetic nervous system through toll-like receptor 4 in mice with heart failure.

Journal: Journal of cardiovascular pharmacology 20111101

Title: Decreased nNOS in the PVN leads to increased sympathoexcitation in chronic heart failure: role for CAPON and Ang II.

Journal: Cardiovascular research 20111101

Title: Mechanisms underlying altered extracellular nucleotide-induced contractions in mesenteric arteries from rats in later-stage type 2 diabetes: effect of ANG II type 1 receptor antagonism.

Journal: American journal of physiology. Heart and circulatory physiology 20111101

Title: In vivo key role of reactive oxygen species and NHE-1 activation in determining excessive cardiac hypertrophy.

Journal: Pflugers Archiv : European journal of physiology 20111101

Title: Angiotensin II receptors modulate muscle microvascular and metabolic responses to insulin in vivo.

Journal: Diabetes 20111101

Title: Blood pressure and renal hemodynamic responses to acute angiotensin II infusion are enhanced in a female mouse model of systemic lupus erythematosus.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20111101

Title: Renin-angiotensin and sympathetic nervous system contribution to high blood pressure in Schlager mice.

Journal: Journal of hypertension 20111101

Title: Therapeutic perspectives in hypertension: novel means for renin-angiotensin-aldosterone system modulation and emerging device-based approaches.

Journal: European heart journal 20111101

Title: Should combination therapy be the paradigm for future nonalcoholic steatohepatitis clinical trials?

Journal: Hepatology (Baltimore, Md.) 20111101

Title: Regulation of angiotensin-(1-7) and angiotensin II type 1 receptor by telmisartan and losartan in adriamycin-induced rat heart failure.

Journal: Acta pharmacologica Sinica 20111101

Title: Blood pressure outcomes in patients receiving angiotensin II receptor blockers in primary care: a comparative effectiveness analysis from electronic medical record data.

Journal: Journal of clinical hypertension (Greenwich, Conn.) 20111101

Title: Spontaneous remission of post-transplant recurrent focal and segmental glomerulosclerosis.

Journal: Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20111101

Title: A pilot study on the effect of telmisartan & ramipril on 24 h blood pressure profile & dipping pattern in type 1 diabetes patients with nephropathy.

Journal: The Indian journal of medical research 20111101

Title: Experimental depression induces renal oxidative stress in rats.

Journal: Physiology & behavior 20111024

Title: 24-Hour ambulatory blood pressure control with triple-therapy amlodipine, valsartan and hydrochlorothiazide in patients with moderate to severe hypertension.

Journal: Journal of human hypertension 20111001

Title: Anabolic steroid associated to physical training induces deleterious cardiac effects.

Journal: Medicine and science in sports and exercise 20111001

Title: Do genetic variants of the Renin-Angiotensin system predict blood pressure response to Renin-Angiotensin system-blocking drugs?: a systematic review of pharmacogenomics in the Renin-Angiotensin system.

Journal: Current hypertension reports 20111001

Title: Contributions of ACE and mast cell chymase to endogenous angiotensin II generation and leucocyte recruitment in vivo.

Journal: Cardiovascular research 20111001

Title: Inflammatory cytokines in paraventricular nucleus modulate sympathetic activity and cardiac sympathetic afferent reflex in rats.

Journal: Acta physiologica (Oxford, England) 20111001

Title: Angiotensin II evokes sensory long-term facilitation of the carotid body via NADPH oxidase.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20111001

Title: Effect of losartan on proteinuria and urinary angiotensinogen excretion in non-diabetic patients with chronic kidney disease.

Journal: Postgraduate medical journal 20111001

Title: Potential antifibrotic effects of AT1 receptor antagonist, losartan, and/or praziquantel on acute and chronic experimental liver fibrosis induced by Schistosoma mansoni.

Journal: Clinical and experimental pharmacology & physiology 20111001

Title: The impact of hepatic uptake on the pharmacokinetics of organic anions.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20111001

Title: Angiotensin III stimulates ERK1/2 mitogen-activated protein kinases and astrocyte growth in cultured rat astrocytes.

Journal: Neuropeptides 20111001

Title: Acute and chronic angiotensin-(1-7) restores vasodilation and reduces oxidative stress in mesenteric arteries of salt-fed rats.

Journal: American journal of physiology. Heart and circulatory physiology 20111001

Title: Frequency of CYP2C9 alleles in Koreans and their effects on losartan pharmacokinetics.

Journal: Acta pharmacologica Sinica 20111001

Title: Management of gout in the older adult.

Journal: The American journal of geriatric pharmacotherapy 20111001

Title: The effect of amlodipine besylate, losartan potassium, olmesartan medoxomil, and other antihypertensives on central aortic blood pressure and biomarkers of vascular function.

Journal: Therapeutic advances in cardiovascular disease 20111001

Title: Combination of fluvastatin and losartan relieves atherosclerosis and macrophage infiltration in atherosclerotic plaques in rabbits.

Journal: Acta pharmacologica Sinica 20111001

Title: Vascular mechanisms involved in angiotensin II-induced venoconstriction in hypertensive rats.

Journal: Peptides 20111001

Title: ACEI and ARB combination therapy in patients with macroalbuminuric diabetic nephropathy and low socioeconomic level: a double-blind randomized clinical trial.

Journal: Clinical nephrology 20111001

Title: To study the efficacy of Losartan on urinary uric acid excretion in Thiazide induced hyperuricemic and hypertensive patients.

Journal: Pakistan journal of pharmaceutical sciences 20111001

Title: Pharmacotherapy review of chronic pediatric hypertension.

Journal: Clinical therapeutics 20111001

Title: Effects of telmisartan on insulin resistance and visceral fat distribution in Chinese hypertensive patients with obesity.

Journal: Saudi medical journal 20111001

Title: [Effects of Chinese herbal medicine Yiqi Zengmin formula on expression of glucose transporter 4 in skeletal muscle in type 2 diabetic rats].

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20111001

Title: Critical evaluation of the optimal medical therapy in the cardiac resynchronization therapy candidates--single centre experience.

Journal: Vnitrni lekarstvi 20111001

Title: Telmisartan versus valsartan in patients with hypertension: effects on cardiovascular, metabolic, and inflammatory parameters.

Journal: Korean circulation journal 20111001

Title: Management of diabetic hypertensives.

Journal: Indian journal of endocrinology and metabolism 20111001

Title: Aliskiren prevents and ameliorates metabolic syndrome in fructose-fed rats.

Journal: Archives of medical science : AMS 20111001

Title: Irregular electrical activation of intrinsic cardiac adrenergic cells increases catecholamine-synthesizing enzymes.

Journal: Biochemical and biophysical research communications 20110930

Title: [Young patient with mild hypertension: angiotensin inhibitor or beta blocker?].

Journal: MMW Fortschritte der Medizin 20110922

Title: Switching control of sympathetic activity from forebrain to hindbrain in chronic dehydration.

Journal: The Journal of physiology 20110915

Title: Pravastatin reduces Marfan aortic dilation.

Journal: Circulation 20110913

Title: [Angioedema due to losartan].

Journal: Medicina clinica 20110910

Title: Role of perivascular adipose tissue-derived methyl palmitate in vascular tone regulation and pathogenesis of hypertension.

Journal: Circulation 20110906

Title: Drug therapy of heart failure: an immunologic view.

Journal: American journal of therapeutics 20110901

Title: Changes in metabolic profile and population of skeletal muscle fibers of mice overexpressing calsequestrin: influence of losartan.

Journal: Acta histochemica 20110901

Title: Losartan potassium/hydrochlorothiazide (Preminent®) and hyponatremia: case series of 40 patients.

Journal: Human & experimental toxicology 20110901

Title: Effect of hypoxia in mice mesenteric arteries surrounded by adipose tissue.

Journal: Acta physiologica (Oxford, England) 20110901

Title: Characterization of a stable, hypertensive rat model suitable for the consecutive evaluation of human renin inhibitors.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20110901

Title: Losartan protects mesenteric arteries from ROS-associated decrease in myogenic constriction following 5/6 nephrectomy.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20110901

Title: Use of enterally delivered angiotensin II type Ia receptor antagonists to reduce the severity of colitis.

Journal: Digestive diseases and sciences 20110901

Title: A systematic review and meta-analysis of candesartan and losartan in the management of essential hypertension.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20110901

Title: Cognitive enhancement following acute losartan in normotensive young adults.

Journal: Psychopharmacology 20110901

Title: NADPH oxidase-dependent formation of reactive oxygen species contributes to angiotensin II-induced epithelial-mesenchymal transition in rat peritoneal mesothelial cells.

Journal: International journal of molecular medicine 20110901

Title: Intracellular angiotensin II activates rat myometrium.

Journal: American journal of physiology. Cell physiology 20110901

Title: Effects of uremic toxins on transport and metabolism of different biopharmaceutics drug disposition classification system xenobiotics.

Journal: Journal of pharmaceutical sciences 20110901

Title: Both AT₁ and AT₂ receptors mediate proliferation and migration of porcine vascular smooth muscle cells.

Journal: American journal of physiology. Heart and circulatory physiology 20110901

Title: Effects of losartan, in monotherapy or in association with hydrochlorothiazide, in chronic nephropathy resulting from losartan treatment during lactation.

Journal: American journal of physiology. Renal physiology 20110901

Title: The clinical value of apex beat and electrocardiography for the detection of left ventricular hypertrophy from the standpoint of the distance factors from the heart to the chest wall: a multislice CT study.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20110901

Title: Phosphoproteomic analysis of AT1 receptor-mediated signaling responses in proximal tubules of angiotensin II-induced hypertensive rats.

Journal: Kidney international 20110901

Title: Impact of systemically active neurohumoral factors on the erectile response of the rat.

Journal: The journal of sexual medicine 20110901

Title: 1-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-pyrrolidine-2-carboxamide: investigation of structural variations.

Journal: Archiv der Pharmazie 20110901

Title: Long-term clinical and economic outcomes associated with angiotensin II receptor blocker use in hypertensive patients.

Journal: Current medical research and opinion 20110901

Title: Glomerular expression of kidney injury molecule-1 and podocytopenia in diabetic glomerulopathy.

Journal: American journal of nephrology 20110901

Title: Retrospective analysis of real-world efficacy of angiotensin receptor blockers versus other classes of antihypertensive agents in blood pressure management.

Journal: Clinical therapeutics 20110901

Title: Compliance, persistence, and switching patterns for ACE inhibitors and ARBs.

Journal: The American journal of managed care 20110901

Title: Interaction between sympathetic nervous system and renin angiotensin system on MMPs expression in juvenile rat aorta.

Journal: General physiology and biophysics 20110901

Title: Acromegaly with no pituitary adenoma and no evidence of ectopic source.

Journal: Indian journal of endocrinology and metabolism 20110901

Title: Subclinical Myocardial Dysfunction in Metabolic Syndrome Patients without Hypertension.

Journal: Journal of cardiovascular ultrasound 20110901

Title: Hypertensive heart failure associated with middle aortic syndrome reversed dramatically by endovascular management.

Journal: Journal of cardiovascular ultrasound 20110901

Title: AT1 receptors activation enhances the expression of MMP-2, MMP-13 and VEGF but not MMP-9 in B16F10 melanoma cells.

Journal: Pakistan journal of biological sciences : PJBS 20110901

Title: Preparation and characterization of pH-independent sustained release tablet containing solid dispersion granules of a poorly water-soluble drug.

Journal: International journal of pharmaceutics 20110830

Title: Angiotensin II does not directly affect Aβ secretion or β-/γ-secretase activity via activation of angiotensin II type 1 receptor.

Journal: Neuroscience letters 20110815

Title: Cardiovascular MRI in clinical trials: expanded applications through novel surrogate endpoints.

Journal: Heart (British Cardiac Society) 20110815

Title: The prognostic value of circulating markers of collagen turnover after acute myocardial infarction.

Journal: International journal of cardiology 20110804

Title: Diabetes: Lowering serum uric acid levels to prevent kidney failure.

Journal: Nature reviews. Nephrology 20110802

Title: Protective actions of des-aspartate-angiotensin I in mice model of CEES-induced lung intoxication.

Journal: Journal of applied toxicology : JAT 20110801

Title: Efficacy and safety of losartan in children with Alport syndrome--results from a subgroup analysis of a prospective, randomized, placebo- or amlodipine-controlled trial.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110801

Title: Effect of atorvastatin on CYP2C9 metabolic activity as measured by the formation rate of losartan metabolite in hypercholesterolaemic patients.

Journal: Basic & clinical pharmacology & toxicology 20110801

Title: An acute fall in estimated glomerular filtration rate during treatment with losartan predicts a slower decrease in long-term renal function.

Journal: Kidney international 20110801

Title: Clinical relevance of liquid chromatography tandem mass spectrometry as an analytical method in microdose clinical studies.

Journal: Pharmaceutical research 20110801

Title: A case of serious laryngeal edema unpredictably detected during laryngoscopy for orotracheal intubation following induction of anesthesia.

Journal: Journal of anesthesia 20110801

Title: Effect of diet, enalapril, or losartan in post-diarrheal hemolytic uremic syndrome nephropathy.

Journal: Pediatric nephrology (Berlin, Germany) 20110801

Title: Fetal uninephrectomy in male sheep alters the systemic and renal responses to angiotensin II infusion and AT1R blockade.

Journal: American journal of physiology. Renal physiology 20110801

Title: Angiotensin II induces microtubule reorganization mediated by a deacetylase SIRT2 in endothelial cells.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20110801

Title: Angiotensin receptor blockade and risk of cancer in type 2 diabetes mellitus: a nationwide case-control study.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110801

Title: Comparison of angiotensin converting enzyme inhibitors and angiotensin II type 1 receptor blockade for the prevention of premalignant changes in the liver.

Journal: Life sciences 20110801

Title: Benefits of Renin-Angiotensin blockade on retinopathy in type 1 diabetes vary with glycemic control.

Journal: Diabetes care 20110801

Title: In-treatment stroke volume predicts cardiovascular risk in hypertension.

Journal: Journal of hypertension 20110801

Title: Inhibition of soluble epoxide hydrolase improves the impaired pressure-natriuresis relationship and attenuates the development of hypertension and hypertension-associated end-organ damage in Cyp1a1-Ren-2 transgenic rats.

Journal: Journal of hypertension 20110801

Title: Acute fall in glomerular filtration rate with renin-angiotensin system inhibition: a biomeasure of therapeutic success?

Journal: Kidney international 20110801

Title: Comments on systematic review of clinical- and cost-effectiveness of candesartan and losartan in hypertension and heart failure.

Journal: International journal of clinical practice 20110801

Title: Effects of antiproteinuric intervention on elevated connective tissue growth factor (CTGF/CCN-2) plasma and urine levels in nondiabetic nephropathy.

Journal: Clinical journal of the American Society of Nephrology : CJASN 20110801

Title: Combination angiotensin-receptor blocker (ARB)/calcium channel blocker with HCTZ vs the maximal recommended dose of an ARB with HCTZ in patients with stage 2 hypertension: the exforge as compared to losartan treatment in stage 2 systolic hypertension (EXALT) study.

Journal: Journal of clinical hypertension (Greenwich, Conn.) 20110801

Title: Influence of demand-side measures to enhance renin-angiotensin prescribing efficiency in Europe: implications for the future.

Journal: Expert review of pharmacoeconomics & outcomes research 20110801

Title: Meeting report: American Aging Association 40th Annual Meeting, Raleigh, North Carolina, June 3-6, 2011.

Journal: Rejuvenation research 20110801

Title: [Effect of losartan on renal expression of monocyte chemoattractant protein-1 and transforming growth factor-β(1) in rats after unilateral ureteral obstruction].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20110801

Title: Rosuvastatin prevents proteinuria and renal inflammation in nitric oxide-deficient rats.

Journal: Clinics (Sao Paulo, Brazil) 20110801

Title: A case of metastatic renal cell carcinoma to thyroid gland.

Journal: Chonnam medical journal 20110801

Title: AT₁ receptor blockade in the lateral parabrachial nucleus reduces the effects of muscimol on sodium intake.

Journal: Brain research 20110727

Title: Hemin decreases cardiac oxidative stress and fibrosis in a rat model of systemic hypertension via PI3K/Akt signalling.

Journal: Cardiovascular research 20110715

Title: Telmisartan protects against diabetic vascular complications in a mouse model of obesity and type 2 diabetes, partially through peroxisome proliferator activated receptor-γ-dependent activity.

Journal: Biochemical and biophysical research communications 20110708

Title: Primary stroke prevention and hypertension treatment: which is the first-line strategy?

Journal: Neurology international 20110705

Title: High level of proteinuria during treatment with renin-angiotensin inhibitors is a strong predictor of renal outcome in nondiabetic kidney disease.

Journal: Journal of clinical pharmacology 20110701

Title: Preventing the aortic complications of Marfan syndrome: a case-example of translational genomic medicine.

Journal: British journal of clinical pharmacology 20110701

Title: Angiotensin II increases periostin expression via Ras/p38 MAPK/CREB and ERK1/2/TGF-β1 pathways in cardiac fibroblasts.

Journal: Cardiovascular research 20110701

Title: Inhibition of NF-κB-induced inflammatory responses by angiotensin II antagonists in aged rat kidney.

Journal: Experimental gerontology 20110701

Title: Mechanism underlying the efficacy of combination therapy with losartan and hydrochlorothiazide in rats with salt-sensitive hypertension.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20110701

Title: Angiotensin II plays a critical role in diabetic pulmonary fibrosis most likely via activation of NADPH oxidase-mediated nitrosative damage.

Journal: American journal of physiology. Endocrinology and metabolism 20110701

Title: The role of the renin-angiotensin system in thoracic aortic aneurysms: clinical implications.

Journal: Pharmacology & therapeutics 20110701

Title: High salt intake abolishes AT(2)-mediated vasodilation of pial arterioles in rats.

Journal: Journal of hypertension 20110701

Title: Characterization of the genomic structure and function of regions influencing renin and angiogenesis in the SS rat.

Journal: Physiological genomics 20110701

Title: Altered regulation of the rostral ventrolateral medulla in hypertensive obese Zucker rats.

Journal: American journal of physiology. Heart and circulatory physiology 20110701

Title: Down-regulation of DDAH2 and eNOS induces endothelial dysfunction in sinoaortic-denervated rats.

Journal: European journal of pharmacology 20110701

Title: Inhibition of renin-angiotensin system (RAS) reduces ventricular tachycardia risk by altering connexin43.

Journal: Journal of molecular medicine (Berlin, Germany) 20110701

Title: Behavior of pharmaceuticals in waste water treatment plant in Japan.

Journal: Bulletin of environmental contamination and toxicology 20110701

Title: Evidence of an intracellular angiotensin-generating system and non-AT1, non-AT2 binding site in a human pancreatic cell line.

Journal: Pancreas 20110701

Title: Successful treatment of nephrotic syndrome caused by recurrent IgA nephropathy with chronic active antibody-mediated rejection three years after kidney transplantation.

Journal: Clinical transplantation 20110701

Title: Effect of a reduction in uric acid on renal outcomes during losartan treatment: a post hoc analysis of the reduction of endpoints in non-insulin-dependent diabetes mellitus with the Angiotensin II Antagonist Losartan Trial.

Journal: Hypertension (Dallas, Tex. : 1979) 20110701

Title: Effects of ticlopidine on pharmacokinetics of losartan and its main metabolite EXP-3174 in rats.

Journal: Acta pharmacologica Sinica 20110701

Title: Caveolae are essential for angiotensin II type 1 receptor-mediated ANP secretion.

Journal: Peptides 20110701

Title: Safety and tolerability of the direct renin inhibitor aliskiren in combination with angiotensin receptor blockers and thiazide diuretics: a pooled analysis of clinical experience of 12,942 patients.

Journal: Journal of clinical hypertension (Greenwich, Conn.) 20110701

Title: Tube feeding and drugs in intensive care unit.

Journal: Anaesthesia and intensive care 20110701

Title: 2-(4-Methyl-phen-yl)benzonitrile.

Journal: Acta crystallographica. Section E, Structure reports online 20110701

Title: Irbesartan attenuates ischemic brain damage by inhibition of MCP-1/CCR2 signaling pathway beyond AT₁ receptor blockade.

Journal: Biochemical and biophysical research communications 20110603

Title: Economic evaluation of irbesartan in combination with hydrochlorothiazide in the treatment of hypertension in Greece.

Journal: The European journal of health economics : HEPAC : health economics in prevention and care 20110601

Title: Olmesartan/amlodipine vs olmesartan/hydrochlorothiazide in hypertensive patients with metabolic syndrome: the OLAS study.

Journal: Journal of human hypertension 20110601

Title: Differential effects of enalapril and losartan on body composition and indices of muscle quality in aged male Fischer 344 × Brown Norway rats.

Journal: Age (Dordrecht, Netherlands) 20110601

Title: Antiarrhythmic effects of losartan and enalapril in canine pulmonary vein sleeve preparations.

Journal: Journal of cardiovascular electrophysiology 20110601

Title: Combination treatment of angiotensin II type I receptor blocker and new oral iron chelator attenuates progression of nonalcoholic steatohepatitis in rats.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20110601

Title: Angiotensin-II type 1 receptor and NOX2 mediate TCF/LEF and CREB dependent WISP1 induction and cardiomyocyte hypertrophy.

Journal: Journal of molecular and cellular cardiology 20110601

Title: Isolation and evaluation of a polysaccharide from Prunus amygdalus as a carrier for transbuccosal delivery of Losartan potassium.

Journal: International journal of biological macromolecules 20110601

Title: Albuminuria and blood pressure, independent targets for cardioprotective therapy in patients with diabetes and nephropathy: a post hoc analysis of the combined RENAAL and IDNT trials.

Journal: European heart journal 20110601

Title: Scintigraphic diagnosis of Erdheim-Chester disease.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110601

Title: Telmisartan exerts antiatherosclerotic effects by activating peroxisome proliferator-activated receptor-γ in macrophages.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20110601

Title: Combining blockers of the renin-angiotensin system or increasing the dose of an angiotensin II receptor antagonist in proteinuric patients: a randomized triple-crossover study.

Journal: Journal of hypertension 20110601

Title: Effect of angiotensin II and its receptor antagonists on human corpus cavernous contractility and oxidative stress: modulation of nitric oxide mediated relaxation.

Journal: The Journal of urology 20110601

Title: [Study of the efficacy and safety of losartan versus atenolol for aortic dilation in patients with Marfan syndrome].

Journal: Revista espanola de cardiologia 20110601

Title: Autonomic imbalance: prophet of doom or scope for hope?

Journal: Diabetic medicine : a journal of the British Diabetic Association 20110601

Title: Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus.

Journal: Diabetes care 20110601

Title: Inhibiting TGF-β activity improves respiratory function in mdx mice.

Journal: The American journal of pathology 20110601

Title: Managing erectile dysfunction in hypertensive patients.

Journal: Journal of clinical hypertension (Greenwich, Conn.) 20110601

Title: The effect of an Angiotensin receptor blocker on arterial stiffness in type 2 diabetes mellitus patients with hypertension.

Journal: Diabetes & metabolism journal 20110601

Title: Epigallocatechin-3-gallate Regulates Inducible Nitric Oxide Synthase Expression in Human Umbilical Vein Endothelial Cells.

Journal: Laboratory animal research 20110601

Title: A sporadic case of Loeys-Dietz syndrome type I with two novel mutations of the TGFBR2 gene.

Journal: Korean journal of pediatrics 20110601

Title: Comparative biophysical studies of sartan class drug molecules losartan and candesartan (CV-11974) with membrane bilayers.

Journal: The journal of physical chemistry. B 20110519

Title: Losartan restores skeletal muscle remodeling and protects against disuse atrophy in sarcopenia.

Journal: Science translational medicine 20110511

Title: Psoriasis induced by losartan therapy: a case report and review of the literature.

Journal: American journal of therapeutics 20110501

Title: Mitigating effects of captopril and losartan on lung histopathology in a rat model of fat embolism.

Journal: The Journal of trauma 20110501

Title: Novel therapeutic approaches for pulmonary fibrosis.

Journal: British journal of pharmacology 20110501

Title: Tubular markers do not predict the decline in glomerular filtration rate in type 1 diabetic patients with overt nephropathy.

Journal: Kidney international 20110501

Title: Low transition rate from normo- and low microalbuminuria to proteinuria in Japanese type 2 diabetic individuals: the Japan Diabetes Complications Study (JDCS).

Journal: Diabetologia 20110501

Title: Efficacy and safety of mizoribine combined with losartan in the treatment of IgA nephropathy: a multicenter, randomized, controlled study.

Journal: The American journal of the medical sciences 20110501

Title: Aliskiren vs. angiotensin receptor blockers in hypertension: meta-analysis of randomized controlled trials.

Journal: American journal of hypertension 20110501

Title: Intrarenal transfer of an intracellular fluorescent fusion of angiotensin II selectively in proximal tubules increases blood pressure in rats and mice.

Journal: American journal of physiology. Renal physiology 20110501

Title: CYP2C9-mediated metabolic activation of losartan detected by a highly sensitive cell-based screening assay.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20110501

Title: Molecular mechanisms of angiotensin II stimulation on aquaporin-2 expression and trafficking.

Journal: American journal of physiology. Renal physiology 20110501

Title: The effect of selective antihypertensive drugs on the vascular remodeling-associated hypertension: insights from a profilin1 transgenic mouse model.

Journal: Journal of cardiovascular pharmacology 20110501

Title: Effect of angiotensin AT1 receptor blockade on sympathetic responses to handgrip in healthy men.

Journal: American journal of hypertension 20110501

Title: Use of an adult rat retinal explant model for screening of potential retinal ganglion cell neuroprotective therapies.

Journal: Investigative ophthalmology & visual science 20110501

Title: Aliskiren in combination with losartan reduces albuminuria independent of baseline blood pressure in patients with type 2 diabetes and nephropathy.

Journal: Clinical journal of the American Society of Nephrology : CJASN 20110501

Title: Changes in subclinical organ damage vs. in Framingham risk score for assessing cardiovascular risk reduction during continued antihypertensive treatment: a LIFE substudy.

Journal: Journal of hypertension 20110501

Title: Pharmacokinetic evaluation of losartan.

Journal: Expert opinion on drug metabolism & toxicology 20110501

Title: Heterogeneity in antihypertensive treatment discontinuation between drugs belonging to the same class.

Journal: Journal of hypertension 20110501

Title: Gadolinium increases the vascular reactivity of rat aortic rings.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20110501

Title: Role of angiotensin-1 receptor blockade in cirrhotic liver resection.

Journal: Liver international : official journal of the International Association for the Study of the Liver 20110501

Title: Highly sensitive imaging of renal microcirculation in vivo using ultrahigh sensitive optical microangiography.

Journal: Biomedical optics express 20110501

Title: An orally active formulation of angiotensin-(1-7) produces an antithrombotic effect.

Journal: Clinics (Sao Paulo, Brazil) 20110501

Title: Impact of pulmonary vascular resistances in heart transplantation for congenital heart disease.

Journal: Current cardiology reviews 20110501

Title: Candesartan vs losartan and mortality in patients with heart failure.

Journal: JAMA 20110420

Title: Candesartan vs losartan and mortality in patients with heart failure.

Journal: JAMA 20110420

Title: Medicine. Frightening risk of Marfan syndrome, and potential treatment, elucidated.

Journal: Science (New York, N.Y.) 20110415

Title: Noncanonical TGFβ signaling contributes to aortic aneurysm progression in Marfan syndrome mice.

Journal: Science (New York, N.Y.) 20110415

Title: Angiotensin II type 2 receptor signaling attenuates aortic aneurysm in mice through ERK antagonism.

Journal: Science (New York, N.Y.) 20110415

Title: Hydrogen sulfide attenuates cardiac dysfunction in a rat model of heart failure: a mechanism through cardiac mitochondrial protection.

Journal: Bioscience reports 20110401

Title: Effects of commonly administered agents and genetics on nebivolol pharmacokinetics: drug-drug interaction studies.

Journal: Journal of clinical pharmacology 20110401

Title: Telmisartan inhibits vasoconstriction via PPARγ-dependent expression and activation of endothelial nitric oxide synthase.

Journal: Cardiovascular research 20110401

Title: Evaluation of metalloprotease inhibitors on hypertension and diabetic nephropathy.

Journal: American journal of physiology. Renal physiology 20110401

Title: Serial assessment of the electrocardiographic strain pattern for prediction of new-onset heart failure during antihypertensive treatment: the LIFE study.

Journal: European journal of heart failure 20110401

Title: Angiotensin-converting enzyme 2 deficiency in whole body or bone marrow-derived cells increases atherosclerosis in low-density lipoprotein receptor-/- mice.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20110401

Title: Endothelin-converting enzyme/neutral endopeptidase inhibitor SLV338 prevents hypertensive cardiac remodeling in a blood pressure-independent manner.

Journal: Hypertension (Dallas, Tex. : 1979) 20110401

Title: Salt-induced renal injury in SHRs is mediated by AT1 receptor activation.

Journal: Journal of hypertension 20110401

Title: Effects of telmisartan, irbesartan, valsartan, candesartan, and losartan on cancers in 15 trials enrolling 138,769 individuals.

Journal: Journal of hypertension 20110401

Title: Adverse drug reaction profile of nanoparticle versus conventional formulation of paclitaxel: An observational study.

Journal: Indian journal of pharmacology 20110401

Title: Effects of spironolactone and losartan on diabetic nephropathy in a type 2 diabetic rat model.

Journal: Diabetes & metabolism journal 20110401

Title: [Effects of heart rate variability and smoothness index on the reversal of hypertensive left ventricular hypertrophy].

Journal: Zhonghua yi xue za zhi 20110329

Title: Angiotensin receptor blockade improves the net balance of cardiac Ca(2+) handling-related proteins in sympathetic hyperactivity-induced heart failure.

Journal: Life sciences 20110328

Title: Changes in electrocardiographic left ventricular hypertrophy and risk of major cardiovascular events in isolated systolic hypertension: the LIFE study.

Journal: Journal of human hypertension 20110301

Title: Medial septal area ANG II receptor subtypes in the regulation of urine and sodium excretion induced by vasopressin.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20110301

Title: Angiotensin II blockade upregulates the expression of Klotho, the anti-ageing gene, in an experimental model of chronic cyclosporine nephropathy.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110301

Title: The frequency of factor V Leiden mutation, ACE gene polymorphism, serum ACE activity and response to ACE inhibitor and angiotensin II receptor antagonist drugs in Iranians type II diabetic patients with microalbuminuria.

Journal: Molecular biology reports 20110301

Title: Endothelium-dependent vasomotor effects of telmisartan in isolated rat femoral arteries.

Journal: Pharmacological research 20110301

Title: The effect of losartan treatment on the response of diabetic cardiomyocytes to ATP depletion.

Journal: Pharmacological research 20110301

Title: Angiotensin II induces interleukin-6 synthesis in osteoblasts through ERK1/2 pathway via AT1 receptor.

Journal: Archives of oral biology 20110301

Title: The effect of losartan and amlodipine on left ventricular diastolic function and atherosclerosis in Japanese patients with mild-to-moderate hypertension (J-ELAN) study.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20110301

Title: Tachycardia of atrial myocytes induces collagen expression in atrial fibroblasts through transforming growth factor β1.

Journal: Cardiovascular research 20110301

Title: Obesity and gastrointestinal hormones-dual effect of angiotensin II receptor blockade and a partial agonist of PPAR-γ.

Journal: Current vascular pharmacology 20110301

Title: Are we ready to use aliskiren in children?

Journal: Pediatric nephrology (Berlin, Germany) 20110301

Title: ANG II type I receptor antagonism improved nitric oxide production and enhanced eNOS and PKB/Akt expression in hearts from a rat model of insulin resistance.

Journal: Molecular and cellular biochemistry 20110301

Title: Angiotensin II differentially modulates cyclooxygenase-2, microsomal prostaglandin E2 synthase-1 and prostaglandin I2 synthase expression in adventitial fibroblasts exposed to inflammatory stimuli.

Journal: Journal of hypertension 20110301

Title: Gene expression, function and ischemia tolerance in male and female rat hearts after sub-toxic levels of angiotensin II.

Journal: Cardiovascular toxicology 20110301

Title: Glucocorticoid-induced fetal programming alters the functional complement of angiotensin receptor subtypes within the kidney.

Journal: Hypertension (Dallas, Tex. : 1979) 20110301

Title: Sympathetic response to insulin is mediated by melanocortin 3/4 receptors in the hypothalamic paraventricular nucleus.

Journal: Hypertension (Dallas, Tex. : 1979) 20110301

Title: Angiotensinergic signaling in the brain mediates metabolic effects of deoxycorticosterone (DOCA)-salt in C57 mice.

Journal: Hypertension (Dallas, Tex. : 1979) 20110301

Title: Impaired interaction between efferent and afferent renal nerve activity in SHR involves increased activation of alpha2-adrenoceptors.

Journal: Hypertension (Dallas, Tex. : 1979) 20110301

Title: Comparative clinical- and cost-effectiveness of candesartan and losartan in the management of hypertension and heart failure: a systematic review, meta- and cost-utility analysis.

Journal: International journal of clinical practice 20110301

Title: Easy money? Health cost savings resulting from the switch from a branded drug to a low-cost generic drug in the same class.

Journal: International journal of clinical practice 20110301

Title: Waste not, want not: free money, moral hazard and value-based prescribing.

Journal: International journal of clinical practice 20110301

Title: Dietary salt intake and mortality in patients with type 2 diabetes.

Journal: Diabetes care 20110301

Title: Losartan decreases cardiac muscle fibrosis and improves cardiac function in dystrophin-deficient mdx mice.

Journal: Journal of cardiovascular pharmacology and therapeutics 20110301

Title: Racial differences in incident heart failure during antihypertensive therapy.

Journal: Circulation. Cardiovascular quality and outcomes 20110301

Title: Cardiovascular events in subgroups of patients during primary treatment of hypertension with candesartan or losartan.

Journal: Journal of clinical hypertension (Greenwich, Conn.) 20110301

Title: Prevention of systemic and regional haemodynamic alterations, hypercreatininemia, hyperuremia and hyperphosphatemia by losartan in hypertension with acute renal failure.

Journal: Acta physiologica Hungarica 20110301

Title: MTHFR C677T polymorphism as a risk factor for vascular calcification in chronic hemodialysis patients.

Journal: Journal of Korean medical science 20110301

Title: Arterial tortuosity syndrome with multiple intracranial aneurysms: a case report.

Journal: Archives of neurology 20110301

Title: Heart failure prevention is the best option to stem high costs and disease burden: research for more effective heart failure treatment is needed.

Journal: Circulation. Cardiovascular quality and outcomes 20110301

Title: Spurious hyperkalaemia: an insight.

Journal: JPMA. The Journal of the Pakistan Medical Association 20110301

Title: Depressogenic effects of medications: a review.

Journal: Dialogues in clinical neuroscience 20110301

Title: [Experimental study of (Pro)renin receptor siRNA inhibiting retinal neovascularization].

Journal: [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20110301

Title: Evaluation of the effects of losartan on a random pattern skin flap model in rats.

Journal: Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES 20110301

Title: An Insufficient Preoperative Diagnosis of Borrmann Type 4 Gastric Cancer in Spite of EMR.

Journal: Journal of gastric cancer 20110301

Title: The angiotensin II type 1 receptor antagonist Losartan binds and activates bradykinin B2 receptor signaling.

Journal: Regulatory peptides 20110225

Title: Angiotensin1-9 antagonises pro-hypertrophic signalling in cardiomyocytes via the angiotensin type 2 receptor.

Journal: The Journal of physiology 20110215

Title: Supramolecular interactions between losartan and hydroxypropyl-β-CD: ESI mass-spectrometry, NMR techniques, phase solubility, isothermal titration calorimetry and anti-hypertensive studies.

Journal: International journal of pharmaceutics 20110214

Title: Health-care costs of losartan and candesartan in the primary treatment of hypertension.

Journal: Journal of human hypertension 20110201

Title: The effects of poststroke captopril and losartan treatment on cerebral blood flow autoregulation in SHRsp with hemorrhagic stroke.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20110201

Title: High glucose upregulates upstream stimulatory factor 2 in human renal proximal tubular cells through angiotensin II-dependent activation of CREB.

Journal: Nephron. Experimental nephrology 20110201

Title: Angiotensin II diminishes the effect of SGK1 on the WNK4-mediated inhibition of ROMK1 channels.

Journal: Kidney international 20110201

Title: Rho kinase inhibition protects kidneys from diabetic nephropathy without reducing blood pressure.

Journal: Kidney international 20110201

Title: FGF-23 as a predictor of renal outcome in diabetic nephropathy.

Journal: Clinical journal of the American Society of Nephrology : CJASN 20110201

Title: Effect of renal sympathetic nerve on adrenergically and angiotensin II-induced renal vasoconstriction in normal Wistar-Kyoto rats.

Journal: Upsala journal of medical sciences 20110201

Title: Pressor effect of apelin-13 in the rostral ventrolateral medulla: role of NAD(P)H oxidase-derived superoxide.

Journal: The Journal of pharmacology and experimental therapeutics 20110201

Title: Role of plasma aldosterone concentration in regression of left-ventricular mass following antihypertensive medication.

Journal: Journal of hypertension 20110201

Title: Endogenous angiotensin II suppresses stretch-induced ANP secretion via AT1 receptor pathway.

Journal: Peptides 20110201

Title: Calcium channel blocker and Rho-associated kinase activity in patients with hypertension.

Journal: Journal of hypertension 20110201

Title: Changes in angiotensin receptors expression play a pivotal role in the renal damage observed in spontaneously hypertensive rats.

Journal: American journal of physiology. Renal physiology 20110201

Title: Enhanced angiotensin II-mediated central sympathoexcitation in streptozotocin-induced diabetes: role of superoxide anion.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20110201

Title: Subtrochanteric fractures after long-term treatment with bisphosphonates: a European Society on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis, and International Osteoporosis Foundation Working Group Report.

Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20110201

Title: Angiotensin AT1 receptors in paraventricular nucleus contribute to sympathetic activation and enhanced cardiac sympathetic afferent reflex in renovascular hypertensive rats.

Journal: Experimental physiology 20110201

Title: Dietary sodium modulates the interaction between efferent and afferent renal nerve activity by altering activation of α2-adrenoceptors on renal sensory nerves.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20110201

Title: AT1 receptors in the paraventricular nucleus mediate the hyperthermia-induced reflex reduction of renal blood flow in rats.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20110201

Title: Additive effect of PPAR-γ agonist and ARB in treatment of experimental IgA nephropathy.

Journal: Pediatric nephrology (Berlin, Germany) 20110201

Title: Blockade of the renin-angiotensin system ameliorates apelin production in 3T3-L1 adipocytes.

Journal: Cardiovascular drugs and therapy 20110201

Title: High rate of regression from micro-macroalbuminuria to normoalbuminuria in children and adolescents with type 1 diabetes treated or not with enalapril: the influence of HDL cholesterol.

Journal: Diabetes care 20110201

Title: Does renin-angiotensin system blockade have a role in preventing diabetic retinopathy? A clinical review.

Journal: International journal of clinical practice 20110201

Title: Effect of celecoxib on the antihypertensive effect of losartan in a rat model of renovascular hypertension.

Journal: Canadian journal of physiology and pharmacology 20110201

Title: Clinical trials of antihypertensives: Nature of control and design.

Journal: Indian journal of pharmacology 20110201

Title: World Kidney Day 2011 - Protect your kidneys, save your heart.

Journal: Archives of medical science : AMS 20110201

Title: Atrial fibrillation induces myocardial fibrosis through angiotensin II type 1 receptor-specific Arkadia-mediated downregulation of Smad7.

Journal: Circulation research 20110121

Title: Blockade of 5-HT3 receptors at septal area increase blood pressure in unanaesthetized rats.

Journal: Autonomic neuroscience : basic & clinical 20110120

Title: Adrenal beta-arrestin 1 inhibition in vivo attenuates post-myocardial infarction progression to heart failure and adverse remodeling via reduction of circulating aldosterone levels.

Journal: Journal of the American College of Cardiology 20110118

Title: Co-operative effects of angiotensin II and caerulein in NFκB activation in pancreatic acinar cells in vitro.

Journal: Regulatory peptides 20110117

Title: Chronic infusion of angiotensin receptor antagonists in the hypothalamic paraventricular nucleus prevents hypertension in a rat model of sleep apnea.

Journal: Brain research 20110112

Title: Association of candesartan vs losartan with all-cause mortality in patients with heart failure.

Journal: JAMA 20110112

Title: Gout therapeutics: new drugs for an old disease.

Journal: Lancet (London, England) 20110108

Title: Medical therapy for advanced pancreatic cancer: work in progress.

Journal: JOP : Journal of the pancreas 20110105

Title: The Ayurvedic Medicine Salacia oblonga Attenuates Diabetic Renal Fibrosis in Rats: Suppression of Angiotensin II/AT1 Signaling.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: Losartan vs. amlodipine treatment in elderly oncologic hypertensive patients: a randomized clinical trial.

Journal: Archives of gerontology and geriatrics 20110101

Title: Sympathetic neurons express and secrete MMP-2 and MT1-MMP to control nerve sprouting via pro-NGF conversion.

Journal: Cellular and molecular neurobiology 20110101

Title: Preferential accumulation and export of high molecular weight FGF-2 by rat cardiac non-myocytes.

Journal: Cardiovascular research 20110101

Title: Naloxone, but not valsartan, preserves responses to hypoglycemia after antecedent hypoglycemia: role of metabolic reprogramming in counterregulatory failure.

Journal: Diabetes 20110101

Title: Blockade of the Renin-Angiotensin system improves insulin receptor signaling and insulin-stimulated skeletal muscle glucose transport in burn injury.

Journal: Shock (Augusta, Ga.) 20110101

Title: ACE gene polymorphism and serum ACE activity in Iranians type II diabetic patients with macroalbuminuria.

Journal: Molecular and cellular biochemistry 20110101

Title: Effects of systemic inhibition of Rho kinase on blood pressure and renal haemodynamics in diabetic rats.

Journal: British journal of pharmacology 20110101

Title: The acute effect of clamped hyperglycemia on the urinary excretion of inflammatory cytokines/chemokines in uncomplicated type 1 diabetes: a pilot study.

Journal: Diabetes care 20110101

Title: Increased serum potassium affects renal outcomes: a post hoc analysis of the Reduction of Endpoints in NIDDM with the Angiotensin II Antagonist Losartan (RENAAL) trial.

Journal: Diabetologia 20110101

Title: Pravastatin normalises peripheral cardiac sympathetic hyperactivity in the spontaneously hypertensive rat.

Journal: Journal of molecular and cellular cardiology 20110101

Title: Sirolimus damages podocytes in rats with protein overload nephropathy.

Journal: Journal of nephrology 20110101

Title: Involvement of the AT1 receptor in the venoconstriction induced by angiotensin II in both the inferior vena cava and femoral vein.

Journal: Peptides 20110101

Title: Endothelin-1 and angiotensin II modulate rate and contraction amplitude in a subpopulation of mouse embryonic stem cell-derived cardiomyocyte-containing bodies.

Journal: Stem cell research 20110101

Title: Mechanisms related to NO-induced motility in differentiated rat aortic smooth muscle cells.

Journal: American journal of physiology. Heart and circulatory physiology 20110101

Title: Angiotensin II induces afterdepolarizations via reactive oxygen species and calmodulin kinase II signaling.

Journal: Journal of molecular and cellular cardiology 20110101

Title: Regulation of posttranscriptional modification as a possible therapeutic approach for retinal neuroprotection.

Journal: Journal of ophthalmology 20110101

Title: Different actions of losartan and ramipril on adipose tissue activity and vascular remodeling biomarkers in hypertensive patients.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20110101

Title: Comparison of the effects of losartan vs. ramipril on several adipocytokines and vascular remodeling biomarkers.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20110101

Title: Lack of heterologous receptor desensitization induced by angiotensin II type 1 receptor activation in isolated normal rat thoracic aorta.

Journal: Vascular pharmacology 20110101

Title: Compliance, persistence, healthcare resource use, and treatment costs associated with aliskiren plus ARB versus ACE inhibitor plus ARB combination therapy: in US patients with hypertension.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20110101

Title: Effects of losartan/hydrochlorothiazide treatment, after change from ARB at usual dosage, on blood pressure and various metabolic parameters including high-molecular weight adiponectin in Japanese male hypertensive subjects.

Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20110101

Title: The cardiorenal syndrome: making the connection.

Journal: International journal of nephrology 20110101

Title: The effect of losartan and carvedilol on vasopressor responses to adrenergic agonists and angiotensin II in the systemic circulation of Sprague Dawley rats.

Journal: Autonomic & autacoid pharmacology 20110101

Title: Captopril and losartan for mitigation of renal injury caused by single-dose total-body irradiation.

Journal: Radiation research 20110101

Title: Clinical drugs undergoing polymorphic metabolism by human cytochrome P450 2C9 and the implication in drug development.

Journal: Current medicinal chemistry 20110101

Title: Extracellular matrix of collagen modulates intracellular calcium handling and electrophysiological characteristics of HL-1 cardiomyocytes with activation of angiotensin II type 1 receptor.

Journal: Journal of cardiac failure 20110101

Title: Standards of medical care in diabetes--2011.

Journal: Diabetes care 20110101

Title: Clinical pearls in general internal medicine.

Journal: Mayo Clinic proceedings 20110101

Title: Diabetes: Treatment with losartan increases risk of adverse renal outcomes.

Journal: Nature reviews. Endocrinology 20110101

Title: Local bone marrow Renin-Angiotensin system and atherosclerosis.

Journal: Cardiology research and practice 20110101

Title: Resistant hypertension workup and approach to treatment.

Journal: International journal of hypertension 20110101

Title: Main results of the ouabain and adducin for Specific Intervention on Sodium in Hypertension Trial (OASIS-HT): a randomized placebo-controlled phase-2 dose-finding study of rostafuroxin.

Journal: Trials 20110101

Title: Synergistic effect of combined HMG-CoA reductase inhibitor and angiotensin-II receptor blocker therapy in patients with chronic heart failure: the HF-COSTAR trial.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20110101

Title: Novel adiponectin-resistin (AR) and insulin resistance (IRAR) indexes are useful integrated diagnostic biomarkers for insulin resistance, type 2 diabetes and metabolic syndrome: a case control study.

Journal: Cardiovascular diabetology 20110101

Title: Costarring statins with ARBs: going to be a smash hit?

Journal: Circulation journal : official journal of the Japanese Circulation Society 20110101

Title: Aortocaval fistula in rat: a unique model of volume-overload congestive heart failure and cardiac hypertrophy.

Journal: Journal of biomedicine & biotechnology 20110101

Title: A randomized, double-blind, forced-titration study to compare olmesartan medoxomil versus losartan potassium in patients with stage 1 and 2 hypertension.

Journal: Postgraduate medicine 20110101

Title: Central angiotensin II stimulation promotes β amyloid production in Sprague Dawley rats.

Journal: PloS one 20110101

Title: Anti-inflammatory effects of anti-hypertensive agents: influence on interleukin-1β secretion by peripheral blood polymorphonuclear leukocytes from patients with essential hypertension.

Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20110101

Title: Novel therapies for resistant focal segmental glomerulosclerosis (FONT) phase II clinical trial: study design.

Journal: BMC nephrology 20110101

Title: Effects of fosinopril and losartan on renal Klotho expression and oxidative stress in spontaneously hypertensive rats.

Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20110101

Title: [Effect of AT₁ receptor on changes of tyrosine hydroxylase-immunoreactivity in rostral ventrolateral medulla induced by brain cholinergic stimuli in rats].

Journal: Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20110101

Title: Angiotensin II induces the expression of c-reactive protein via MAPK-dependent signal pathway in U937 macrophages.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20110101

Title: High dose astaxanthin lowers blood pressure and increases insulin sensitivity in rats: are these effects interdependent?

Journal: International journal of medical sciences 20110101

Title: Sympathetic renal innervation and resistant hypertension.

Journal: International journal of hypertension 20110101

Title: Ask the doctor. I heard about a study that found that ARBs can cause cancer. I am taking one, Cozaar, because of high blood pressure. Should I stop taking it?

Journal: Harvard health letter 20110101

Title: A comparison between diuretics and angiotensin-receptor blocker agents in patients with stage I hypertension (PREVER-treatment trial): study protocol for a randomized double-blind controlled trial.

Journal: Trials 20110101

Title: Impairment of the Plasmodium falciparum erythrocytic cycle induced by angiotensin peptides.

Journal: PloS one 20110101

Title: Low-level lead exposure increases systolic arterial pressure and endothelium-derived vasodilator factors in rat aortas.

Journal: PloS one 20110101

Title: [Progress of pediatric nephrology].

Journal: Nihon Jinzo Gakkai shi 20110101

Title: Telmisartan in incipient and overt diabetic renal disease.

Journal: Journal of nephrology 20110101

Title: Olmesartan, an AT1 antagonist, attenuates oxidative stress, endoplasmic reticulum stress and cardiac inflammatory mediators in rats with heart failure induced by experimental autoimmune myocarditis.

Journal: International journal of biological sciences 20110101

Title: Use of Angiotensin receptor blockers in cardiovascular protection: current evidence and future directions.

Journal: P & T : a peer-reviewed journal for formulary management 20110101

Title: Prevalence and distribution of regional scar in dysfunctional myocardial segments in Duchenne muscular dystrophy.

Journal: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20110101

Title: Animal models of cardiovascular diseases.

Journal: Journal of biomedicine & biotechnology 20110101

Title: Sex differences in drug disposition.

Journal: Journal of biomedicine & biotechnology 20110101

Title: Renal protection with angiotensin receptor blockers: where do we stand.

Journal: Journal of nephrology 20110101

Title: Changes in the organization of excitation-contraction coupling structures in failing human heart.

Journal: PloS one 20110101

Title: Candesartan cilexetil/hydrochlorothiazide combination treatment versus high-dose candesartan cilexetil monotherapy in patients with mild to moderate cardiovascular risk (CHILI Triple T).

Journal: Vascular health and risk management 20110101

Title: Common secondary causes of resistant hypertension and rational for treatment.

Journal: International journal of hypertension 20110101

Title: A causative link between periodontal disease and glomerulonephritis: a preliminary study.

Journal: Therapeutics and clinical risk management 20110101

Title: The Ras antagonist, farnesylthiosalicylic acid (FTS), decreases fibrosis and improves muscle strength in dy/dy mouse model of muscular dystrophy.

Journal: PloS one 20110101

Title: Role of the kidneys in resistant hypertension.

Journal: International journal of hypertension 20110101

Title: Pharmaco-economic consequences of losartan therapy in patients undergoing diabetic end stage renal disease in EU and USA.

Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20110101

Title: Treatment options for hypertension in high-risk patients.

Journal: Vascular health and risk management 20110101

Title: Change of telomere length in angiotensin II-induced human glomerular mesangial cell senescence and the protective role of losartan.

Journal: Molecular medicine reports 20110101

Title: Angiotensin II receptor blocker, losartan, ameliorates gentamicin-induced oxidative stress and nephrotoxicity in rats.

Journal: Pharmacology 20110101

Title: Differences in abundances of cell-signalling proteins in blood reveal novel biomarkers for early detection of clinical Alzheimer's disease.

Journal: PloS one 20110101

Title: Inhibition of renin-angiotensin system reverses endothelial dysfunction and oxidative stress in estrogen deficient rats.

Journal: PloS one 20110101

Title: Olmesartan medoxomil for the treatment of hypertension in children and adolescents.

Journal: Vascular health and risk management 20110101

Title: Olmesartan/amlodipine: a review of its use in the management of hypertension.

Journal: Vascular health and risk management 20110101

Title: Screening for left ventricular hypertrophy in patients with type 2 diabetes mellitus in the community.

Journal: Cardiovascular diabetology 20110101

Title: Tanshinone IIA protects against cardiac hypertrophy via inhibiting calcineurin/NFATc3 pathway.

Journal: International journal of biological sciences 20110101

Title: Acute lead exposure increases arterial pressure: role of the renin-angiotensin system.

Journal: PloS one 20110101

Title: [Remarkable results with candesartan].

Journal: Nederlands tijdschrift voor geneeskunde 20110101

Title: BICEPP: an example-based statistical text mining method for predicting the binary characteristics of drugs.

Journal: BMC bioinformatics 20110101

Title: [Effect of losartan, lisinopril and their combination on hemodynamics and morphofunctional parameters of the heart in patients with chronic cardiac failure].

Journal: Klinicheskaia meditsina 20110101

Title: Angiotensin receptor blockers and risk of myocardial infarction: meta-analyses and trial sequential analyses of 147 020 patients from randomised trials.

Journal: BMJ (Clinical research ed.) 20110101

Title: Time course of collagen peak in bile duct-ligated rats.

Journal: BMC gastroenterology 20110101

Title: Losartan and pioglitazone ameliorate nephropathy in experimental metabolic syndrome rats.

Journal: Biological & pharmaceutical bulletin 20110101

Title: The rostral migratory stream plays a key role in intranasal delivery of drugs into the CNS.

Journal: PloS one 20110101

Title: The prognostic value of non-linear analysis of heart rate variability in patients with congestive heart failure--a pilot study of multiscale entropy.

Journal: PloS one 20110101

Title: Strain differences and the role of AT(1) receptor expression in anxiety.

Journal: International journal of molecular epidemiology and genetics 20110101

Title: Nephrotic syndrome and idiopathic membranous nephropathy associated with autosomal-dominant polycystic kidney disease.

Journal: TheScientificWorldJournal 20110101

Title: Major inducing factors of hypertensive complications and the interventions required to reduce their prevalence: an epidemiological study of hypertension in a rural population in China.

Journal: BMC public health 20110101

Title: Incidence of atrial fibrillation in patients with either heart failure or acute myocardial infarction and left ventricular dysfunction: a cohort study.

Journal: BMC cardiovascular disorders 20110101

Title: Clinical utility of valsartan in the treatment of hypertension in children and adolescents.

Journal: Patient preference and adherence 20110101

Title: [Assessment of the results of 24-hour arterial pressure monitoring in patients with arterial hypertension treated with fixed combinations of co-renitec and gyzaar with and without acupuncture reflexotherapy].

Journal: Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury 20110101

Title: Phase I Clinical Study of the Dietary Supplement, Agaricus blazei Murill, in Cancer Patients in Remission.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: Involvement of profilin-1 in angiotensin II-induced vascular smooth muscle cell proliferation.

Journal: Vascular pharmacology 20110101

Title: Cardiovascular and Renal Links along the Cardiorenal Continuum.

Journal: International journal of nephrology 20110101

Title: ARB treatment prevents the decrease in endothelial progenitor cells and the loss of renal microvasculature in remnant kidney.

Journal: American journal of nephrology 20110101

Title: Rapid simultaneous determination of telmisartan, amlodipine besylate and hydrochlorothiazide in a combined poly pill dosage form by stability-indicating ultra performance liquid chromatography.

Journal: Scientia pharmaceutica 20110101

Title: Left ventricular geometric patterns and adaptations to hemodynamics are similar in elderly men and women.

Journal: BMC cardiovascular disorders 20110101

Title: Combination delapril/manidipine as antihypertensive therapy in high-risk patients.

Journal: Clinical drug investigation 20110101

Title: Quantifying differential gene connectivity between disease states for objective identification of disease-relevant genes.

Journal: BMC systems biology 20110101

Title: Novel ocular antihypertensive compounds in clinical trials.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20110101

Title: Prolonged Refractory Hypotension following Combined Amlodipine and Losartan Ingestion Responsive to Metaraminol.

Journal: Case reports in medicine 20110101

Title: Long-term use of aldosterone-receptor antagonists in uncontrolled hypertension: a retrospective analysis.

Journal: International journal of hypertension 20110101

Title: Reappraisal of role of angiotensin receptor blockers in cardiovascular protection.

Journal: Vascular health and risk management 20110101

Title: A current evaluation of the safety of angiotensin receptor blockers and direct renin inhibitors.

Journal: Vascular health and risk management 20110101

Title: Fosinopril and losartan regulate klotho gene and nicotinamide adenine dinucleotide phosphate oxidase expression in kidneys of spontaneously hypertensive rats.

Journal: Kidney & blood pressure research 20110101

Title: Vitamin d receptor activators and clinical outcomes in chronic kidney disease.

Journal: International journal of nephrology 20110101

Title: Switching therapy from variable-dose multiple pill to fixed-dose single-pill combinations of angiotensin II receptor blockers and thiazides for hypertension.

Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20110101

Title: Association of angiotensin-converting enzyme gene I/D polymorphism with steroid responsiveness in childhood nephrotic syndrome.

Journal: Indian journal of nephrology 20110101

Title: Collagenofibrotic glomerulopathy - Case report with review of literature.

Journal: Indian journal of nephrology 20110101

Title: Hypoxemia in patients with COPD: cause, effects, and disease progression.

Journal: International journal of chronic obstructive pulmonary disease 20110101

Title: PLCβ1-SHP-2 complex, PLCβ1 tyrosine dephosphorylation and SHP-2 phosphatase activity: a new part of Angiotensin II signaling?

Journal: Journal of biomedical science 20110101

Title: Aliskiren: An orally active renin inhibitor.

Journal: Journal of pharmacy & bioallied sciences 20110101

Title: Stroke, high blood pressure and the Renin-Angiotensin-aldosterone system - new developments.

Journal: Frontiers in pharmacology 20110101

Title: Diabetic microvascular complications: possible targets for improved macrovascular outcomes.

Journal: International journal of nephrology and renovascular disease 20110101

Title: Role of aliskiren in blood pressure control and renoprotection.

Journal: International journal of nephrology and renovascular disease 20110101

Title: GENT: gene expression database of normal and tumor tissues.

Journal: Cancer informatics 20110101

Title: Decorin and colchicine as potential treatments for post-haemorrhagic ventricular dilatation in a neonatal rat model.

Journal: Neonatology 20110101

Title: Choice of angiotensin receptor blocker in moderate hypertension. A UK-based cost-benefit comparison of olmesartan- and candesartan-based regimens.

Journal: Journal of medical economics 20110101

Title: Effects of HMG-CoA reductase inhibitors on the pharmacokinetics of losartan and its main metabolite EXP-3174 in rats: possible role of CYP3A4 and P-gp inhibition by HMG-CoA reductase inhibitors.

Journal: Pharmacology 20110101

Title: Cardiovascular risk factor treatment targets and renal complications in high risk vascular patients: a cohort study.

Journal: BMC cardiovascular disorders 20110101

Title: Chronic losartan administration reduces mortality and preserves cardiac but not skeletal muscle function in dystrophic mice.

Journal: PloS one 20110101

Title: The ECG vertigo in diabetes and cardiac autonomic neuropathy.

Journal: Experimental diabetes research 20110101

Title: Metabolic programming during lactation stimulates renal Na+ transport in the adult offspring due to an early impact on local angiotensin II pathways.

Journal: PloS one 20110101

Title: Hypertension in chronic kidney disease: navigating the evidence.

Journal: International journal of hypertension 20110101

Title: Cardiac hypertrophy and fibrosis in the metabolic syndrome: a role for aldosterone and the mineralocorticoid receptor.

Journal: International journal of hypertension 20110101

Title: Oxidative Stress and Vascular Damage in Hypertension: Role of Angiotensin II.

Journal: International journal of hypertension 20110101

Title: The mechanosensory role of primary cilia in vascular hypertension.

Journal: International journal of vascular medicine 20110101

Title: Donepezil, anti-Alzheimer's disease drug, prevents cardiac rupture during acute phase of myocardial infarction in mice.

Journal: PloS one 20110101

Title: Oxidative stress in cardiovascular inflammation: its involvement in autoimmune responses.

Journal: International journal of inflammation 20110101

Title: Differential Effects in Cardiovascular Markers between High-Dose Angiotensin II Receptor Blocker Monotherapy and Combination Therapy of ARB with Calcium Channel Blocker in Hypertension (DEAR Trial).

Journal: International journal of hypertension 20110101

Title: Left ventricular hypertrophy: major risk factor in patients with hypertension: update and practical clinical applications.

Journal: International journal of hypertension 20110101

Title: Vascular pathology in multiple sclerosis: mind boosting or myth busting?

Journal: Experimental & translational stroke medicine 20110101

Title: Preventive effect of Ibrolipim on suppressing lipid accumulation and increasing lipoprotein lipase in the kidneys of diet-induced diabetic minipigs.

Journal: Lipids in health and disease 20110101

Title: Diabetic nephropathy - Epidemiology in Asia and the current state of treatment.

Journal: Indian journal of nephrology 20110101

Title: Late post-transplant erythrocytosis in a hepatitis C-positive allograft recipient on sirolimus.

Journal: Indian journal of nephrology 20110101

Title: Dyslipidemia induced by drugs used for the prevention and treatment of vascular diseases.

Journal: The open cardiovascular medicine journal 20110101

Title: Update on the Serum Biomarkers and Genetic Factors Associated with Safety and Efficacy of rt-PA Treatment in Acute Stroke Patients.

Journal: Stroke research and treatment 20110101

Title: The Relation between Fructose-Induced Metabolic Syndrome and Altered Renal Haemodynamic and Excretory Function in the Rat.

Journal: International journal of nephrology 20110101

Title: [The role of D2 vitamin metabolite paricalcitol in nephroprotective strategy in chronic disease of the kidneys].

Journal: Terapevticheskii arkhiv 20110101

Title: Moderate dietary sodium restriction added to angiotensin converting enzyme inhibition compared with dual blockade in lowering proteinuria and blood pressure: randomised controlled trial.

Journal: BMJ (Clinical research ed.) 20110101

Title: Evaluation of CYP450 inhibitory effects and steady-state pharmacokinetics of genistein in combination with cholecalciferol and citrated zinc bisglycinate in postmenopausal women.

Journal: International journal of women's health 20110101

Title: The roles of buyang huanwu decoction in anti-inflammation, antioxidation and regulation of lipid metabolism in rats with myocardial ischemia.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: Inflammatory regulation of valvular remodeling: the good(?), the bad, and the ugly.

Journal: International journal of inflammation 20110101

Title: Cardiovascular outcomes with angiotensin II receptor blockers: clinical implications of recent trials.

Journal: Vascular health and risk management 20110101

Title: Optimal therapeutic strategy for treating patients with hypertension and atherosclerosis: focus on olmesartan medoxomil.

Journal: Vascular health and risk management 20110101

Title: The effects of chronic losartan pretreatment on restraint stress-induced changes in motor activity, nociception and pentylenetetrazol generalized seizures in rats.

Journal: Folia medica 20110101

Title: Combination of angiotensin II receptor antagonist with calcium channel blocker or diuretic as antihypertensive therapy for patients with chronic kidney disease.

Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20110101

Title: δ-Sarcoglycan-deficient muscular dystrophy: from discovery to therapeutic approaches.

Journal: Skeletal muscle 20110101

Title: Role of TGF-β signaling in inherited and acquired myopathies.

Journal: Skeletal muscle 20110101

Title: Aberrant repair and fibrosis development in skeletal muscle.

Journal: Skeletal muscle 20110101

Title: Caloric intake, dietary lifestyles, macronutrient composition, and alzheimer' disease dementia.

Journal: International journal of Alzheimer's disease 20110101

Title: Clopidogrel effectively suppresses endothelial microparticle generation induced by indoxyl sulfate via inhibition of the p38 mitogen-activated protein kinase pathway.

Journal: Blood purification 20110101

Title: Angiotensin II Type 1 Receptors and Systemic Hemodynamic and Renal Responses to Stress and Altered Blood Volume in Conscious Rabbits.

Journal: Frontiers in physiology 20110101

Title: ACE2-mediated reduction of oxidative stress in the central nervous system is associated with improvement of autonomic function.

Journal: PloS one 20110101

Title: Comparative effect of olmesartan and candesartan on lipid metabolism and renal function in patients with hypertension: a retrospective observational study.

Journal: Cardiovascular diabetology 20110101

Title: Reciprocal roles of angiotensin II and Angiotensin II Receptors Blockade (ARB) in regulating Cbfa1/RANKL via cAMP signaling pathway: possible mechanism for hypertension-related osteoporosis and antagonistic effect of ARB on hypertension-related osteoporosis.

Journal: International journal of molecular sciences 20110101

Title: Impaired vascular contractility and aortic wall degeneration in fibulin-4 deficient mice: effect of angiotensin II type 1 (AT1) receptor blockade.

Journal: PloS one 20110101

Title: Urinary angiotensinogen as a biomarker of nephropathy in childhood.

Journal: International journal of nephrology 20110101

Title: The 'smoker's paradox' in patients with acute coronary syndrome: a systematic review.

Journal: BMC medicine 20110101

Title: Drug Delivery: Enabling Technology for Drug Discovery and Development. iPRECIO Micro Infusion Pump: Programmable, Refillable, and Implantable.

Journal: Frontiers in pharmacology 20110101

Title: Where are we heading with noninvasive clinical vascular physiology? Why and how should we assess endothelial function?

Journal: Cardiology research and practice 20110101

Title: Spectrum of antihypertensive therapy in South Asians at a tertiary care hospital in Pakistan.

Journal: BMC research notes 20110101

Title: Validated RP-HPLC Method for Simultaneous Quantitation of Losartan Potassium and Metolazone in Bulk Drug and Formulation.

Journal: Scientia pharmaceutica 20110101

Title: Amoxicillin loaded chitosan-alginate polyelectrolyte complex nanoparticles as mucopenetrating delivery system for h. Pylori.

Journal: Scientia pharmaceutica 20110101

Title: The relationship of ethnicity to the prevalence and management of hypertension and associated chronic kidney disease.

Journal: BMC nephrology 20110101

Title: Prevention and intervention studies with telmisartan, ramipril and their combination in different rat stroke models.

Journal: PloS one 20110101

Title: Rituximab resistant evans syndrome and autoimmunity in Schimke immuno-osseous dysplasia.

Journal: Pediatric rheumatology online journal 20110101

Title: Thrombotic thrombocytopenic purpura associated with mixed connective tissue disease: a case report.

Journal: Case reports in medicine 20110101

Title: Vascular inflammation and endothelial dysfunction in experimental hypertension.

Journal: International journal of hypertension 20110101

Title: Jak2-Independent Activation of Stat3 by Intracellular Angiotensin II in Human Mesangial Cells.

Journal: Journal of signal transduction 20110101

Title: Simultaneous determination of amlodipine and valsartan.

Journal: Analytical chemistry insights 20110101

Title: A critical appraisal of the clinical effectiveness of a fixed combination of valsartan, amlodipine, and hydrochlorothiazide in achieving blood pressure goals.

Journal: Integrated blood pressure control 20110101

Title: Long-term use and tolerability of irbesartan for control of hypertension.

Journal: Integrated blood pressure control 20110101

Title: Short- and long-term physiologic and pharmacologic control of blood pressure in pediatric patients.

Journal: Integrated blood pressure control 20110101

Title: Expression and function of osteopontin in vascular adventitial fibroblasts and pathological vascular remodeling.

Journal: PloS one 20110101

Title: Beneficial effect of switching from a combination of angiotensin II receptor blockers other than losartan and thiazides to a fixed dose of losartan/hydrochlorothiazide on uric acid metabolism in hypertensive patients.

Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20110101

Title: Clinical characterization of symptomatic microangiopathic brain lesions.

Journal: Frontiers in neurology 20110101

Title: Gαq-protein carboxyl terminus imitation polypeptide GCIP-27 attenuates proliferation of vascular smooth muscle cells and vascular remodeling in spontaneously hypertensive rats.

Journal: Biological & pharmaceutical bulletin 20110101

Title: Oxidative damages in tubular epithelial cells in IgA nephropathy: role of crosstalk between angiotensin II and aldosterone.

Journal: Journal of translational medicine 20110101

Title: Generation of reactive oxygen species in 1-methyl-4-phenylpyridinium (MPP+) treated dopaminergic neurons occurs as an NADPH oxidase-dependent two-wave cascade.

Journal: Journal of neuroinflammation 20110101

Title: RhoA distribution in renal caveolar fractions in experimental type 1 diabetes.

Journal: Folia biologica 20110101

Title: Novel microwell-based spectrophotometric assay for determination of atorvastatin calcium in its pharmaceutical formulations.

Journal: Chemistry Central journal 20110101

Title: Inhibition of cardiac sympathetic afferent reflex and sympathetic activity by baroreceptor and vagal afferent inputs in chronic heart failure.

Journal: PloS one 20110101

Title: Functional evaluation of genetic and environmental regulators of p450 mRNA levels.

Journal: PloS one 20110101

Title: The effect of short-term canola oil ingestion on oxidative stress in the vasculature of stroke-prone spontaneously hypertensive rats.

Journal: Lipids in health and disease 20110101

Title: Spice up the hypertension diet - curcumin and piperine prevent remodeling of aorta in experimental L-NAME induced hypertension.

Journal: Nutrition & metabolism 20110101

Title: Eplerenone prevents salt-induced vascular stiffness in Zucker diabetic fatty rats: a preliminary report.

Journal: Cardiovascular diabetology 20110101

Title: Effects of steroids and angiotensin converting enzyme inhibition on circumferential strain in boys with Duchenne muscular dystrophy: a cross-sectional and longitudinal study utilizing cardiovascular magnetic resonance.

Journal: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20110101

Title: Ranitidine anaphylaxis: A rare occurrence.

Journal: Indian journal of anaesthesia 20110101

Title: Molecular mechanisms of left ventricular hypertrophy (LVH) in systemic hypertension (SH)-possible therapeutic perspectives.

Journal: Journal of the American Society of Hypertension : JASH 20110101

Title: Multimodal cardiovascular magnetic resonance quantifies regional variation in vascular structure and function in patients with coronary artery disease: relationships with coronary disease severity.

Journal: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20110101

Title: Inverse agonism and its therapeutic significance.

Journal: Indian journal of pharmacology 20110101

Title: Night-time exogenous melatonin administration may be a beneficial treatment for sleeping disorders in beta blocker patients.

Journal: Journal of cardiovascular disease research 20110101

Title: Efficacy of fixed-dose amlodipine and losartan combination compared with amlodipine monotherapy in stage 2 hypertension: a randomized, double blind, multicenter study.

Journal: BMC research notes 20110101

Title: Comparison of the efficacy and safety of single-pill fixed-dose combinations of losartan/hydrochlorothiazide and valsartan/hydrochlorothiazide in patients with hypertension (SALT-VAT study).

Journal: Internal medicine (Tokyo, Japan) 20110101

Title: Predicting in vivo anti-hepatofibrotic drug efficacy based on in vitro high-content analysis.

Journal: PloS one 20110101

Title: Proteomic and transcriptomic analysis of heart failure due to volume overload in a rat aorto-caval fistula model provides support for new potential therapeutic targets - monoamine oxidase A and transglutaminase 2.

Journal: Proteome science 20110101

Title: Role of blood cell-associated angiotensin II type 1 receptors in the cerebral microvascular response to ischemic stroke during angiotensin-induced hypertension.

Journal: Experimental & translational stroke medicine 20110101

Title: Vascular involvement in systemic sclerosis (scleroderma).

Journal: Journal of inflammation research 20110101

Title: Indications for and utilization of angiotensin receptor II blockers in patients at high cardiovascular risk.

Journal: Vascular health and risk management 20110101

Title: The impact of dose of the angiotensin-receptor blocker valsartan on the post-myocardial infarction ventricular remodeling: study protocol for a randomized controlled trial.

Journal: Trials 20110101

Title: Angiotensin II type II receptor deficiency accelerates the development of nephropathy in type I diabetes via oxidative stress and ACE2.

Journal: Experimental diabetes research 20110101

Title: Design, synthesis, and pharmacological evaluation of haloperidol derivatives as novel potent calcium channel blockers with vasodilator activity.

Journal: PloS one 20110101

Title: Identification and determination of selected angiotensin II receptor antagonist group drugs by HPLC method.

Journal: Acta poloniae pharmaceutica 20110101

Title: Elevation of the antifibrotic peptide N-acetyl-seryl-aspartyl-lysyl-proline: a blood pressure-independent beneficial effect of angiotensin I-converting enzyme inhibitors.

Journal: Fibrogenesis & tissue repair 20110101

Title: Gene-drug interaction in stroke.

Journal: Stroke research and treatment 20110101

Title: Development of validated stability-indicating chromatographic method for the determination of fexofenadine hydrochloride and its related impurities in pharmaceutical tablets.

Journal: Chemistry Central journal 20110101

Title: Telmisartan and cardioprotection.

Journal: Vascular health and risk management 20110101

Title: Azathioprine induced cholestatic hepatitis.

Journal: Indian journal of pharmacology 20110101

Title: Zofenopril and incidence of cough: a review of published and unpublished data.

Journal: Therapeutics and clinical risk management 20110101

Title: The NTD Nanoscope: potential applications and implementations.

Journal: BMC bioinformatics 20110101

Title: Ambulatory blood pressure response to triple therapy with an angiotensin-receptor blocker (ARB), calcium-channel blocker (CCB), and HCTZ versus dual therapy with an ARB and HCTZ.

Journal: Vascular health and risk management 20110101

Title: [Lozartan potential in hyperuricemia correction].

Journal: Terapevticheskii arkhiv 20110101

Title: Constructing a semantic predication gold standard from the biomedical literature.

Journal: BMC bioinformatics 20110101

Title: Roles of TGF-β signals in endothelial-mesenchymal transition during cardiac fibrosis.

Journal: International journal of inflammation 20110101

Title: Clinical and functional characterization of URAT1 variants.

Journal: PloS one 20110101

Title: Antihypertensive treatment differentially affects vascular sphingolipid biology in spontaneously hypertensive rats.

Journal: PloS one 20110101

Title: Cardiovascular agents affect the tone of pulmonary arteries and veins in precision-cut lung slices.

Journal: PloS one 20110101

Title: Catastrophic complication - Bezold-Jarisch reflex: Case series.

Journal: Indian journal of anaesthesia 20110101

Title: TRC120038, a Novel Dual AT(1)/ET(A) Receptor Blocker for Control of Hypertension, Diabetic Nephropathy, and Cardiomyopathy in ob-ZSF1 Rats.

Journal: International journal of hypertension 20110101

Title: Critical review of cancer risk associated with angiotensin receptor blocker therapy.

Journal: Vascular health and risk management 20110101

Title: Differential clinical profile of candesartan compared to other angiotensin receptor blockers.

Journal: Vascular health and risk management 20110101

Title: Benefits of once-daily therapies in the treatment of hypertension.

Journal: Vascular health and risk management 20110101

Title: Integrated control of hypertension by olmesartan medoxomil and hydrochlorothiazide and rationale for combination.

Journal: Integrated blood pressure control 20110101

Title: Short-Term Calorie Restriction in Early Life Attenuates the Development of Proteinuria but Not Glucose Intolerance in Type 2 Diabetic OLETF Rats.

Journal: ISRN endocrinology 20110101

Title: Novel Pharmacological Interventions to Maintain Sinus Rhythm after DC Cardioversion.

Journal: ISRN cardiology 20110101

Title: Aggressive versus Low Dose Inhibition of the Renin-Angiotensin System for the Treatment of Microalbuminuria in Type 2 Diabetic Patients: A Pilot Study.

Journal: ISRN endocrinology 20110101

Title: Results of a Pilot Randomized Placebo-Controlled Trial in Primary and Secondary Raynaud's Phenomenon with St. John's Wort: Detecting Changes in Angiogenic Cytokines When RP Improves.

Journal: ISRN rheumatology 20110101

Title: Physical activity in the prevention and treatment of stroke.

Journal: ISRN neurology 20110101

Title: A Sensitive RP-HPLC Method for Simultaneous Estimation of Diethylcarbamazine and Levocetirizine in Tablet Formulation.

Journal: Indian journal of pharmaceutical sciences 20110101

Title: Quantitative estimation of urate transport in nephrons in relation to urinary excretion employing benzbromarone-loading urate clearance tests in cases of hyperuricemia.

Journal: Nephron extra 20110101

Title: Attenuation of Immune-Mediated Renal Injury by Telmisartan, an Angiotensin Receptor Blocker and a Selective PPAR-γ Activator.

Journal: Nephron extra 20110101

Title: [Current management of gout].

Journal: Acta medica portuguesa 20110101

Title: The effect of contrast dye injection and balloon inflation on QTC and QTC dispersion in 12 leads surface EKG during PTCA.

Journal: ARYA atherosclerosis 20110101

Title: Renoprotective effects of combining ACE inhibitors and statins in experimental diabetic rats.

Journal: Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20110101

Title: Angiotensin II, a Neuropeptide at the Frontier between Endocrinology and Neuroscience: Is There a Link between the Angiotensin II Type 2 Receptor and Alzheimer's Disease?

Journal: Frontiers in endocrinology 20110101

Title: A Stability-indicating High Performance Liquid Chromatographic Assay for the Simultaneous Determination of Atenolol and Lercanidipine Hydrochloride in Tablets.

Journal: Indian journal of pharmaceutical sciences 20110101

Title: [Primary and secondary prevention of ischemic stroke].

Journal: Le Journal medical libanais. The Lebanese medical journal 20110101

Title: Getting better value from the NHS drug budget.

Journal: BMJ (Clinical research ed.) 20101217

Title: Differential effects of alendronate and losartan therapy on osteopenia and aortic aneurysm in mice with severe Marfan syndrome.

Journal: Human molecular genetics 20101215

Title: Angiotensin II receptor type 1 (AT1) selective nonpeptidic antagonists--a perspective.

Journal: Bioorganic & medicinal chemistry 20101215

Title: The physicochemical properties, in vitro metabolism and pharmacokinetics of a novel ester prodrug of EXP3174.

Journal: Molecular pharmaceutics 20101206

Title: Polymorphisms of human cytochrome P450 2C9 and the functional relevance.

Journal: Toxicology 20101205

Title: Xenon/remifentanil anesthesia protects against adverse effects of losartan on hemodynamic challenges induced by anesthesia and acute blood loss.

Journal: Shock (Augusta, Ga.) 20101201

Title: The effect of the expression of angiotensin II on extracellular matrix metalloproteinase inducer (EMMPRIN) in macrophages is mediated via the AT1/COX-2/PGE2 pathway.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20101201

Title: Early molecular imaging of interstitial changes in patients after myocardial infarction: comparison with delayed contrast-enhanced magnetic resonance imaging.

Journal: Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 20101201

Title: Acute hyperglycemia rapidly stimulates VEGF mRNA translation in the kidney. Role of angiotensin type 2 receptor (AT2).

Journal: Cellular signalling 20101201

Title: Vascular structure and oxidative stress in salt-loaded spontaneously hypertensive rats: effects of losartan and atenolol.

Journal: American journal of hypertension 20101201

Title: Regression of target organ damage in children and adolescents with primary hypertension.

Journal: Pediatric nephrology (Berlin, Germany) 20101201

Title: Selectively engaging β-arrestins at the angiotensin II type 1 receptor reduces blood pressure and increases cardiac performance.

Journal: The Journal of pharmacology and experimental therapeutics 20101201

Title: AT₁ receptor and NAD(P)H oxidase mediate angiotensin II-stimulated antioxidant enzymes and mitogen-activated protein kinase activity in the rat hypothalamus.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20101201

Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201

Title: Candesartan attenuates diabetic retinal vascular pathology by restoring glyoxalase-I function.

Journal: Diabetes 20101201

Title: Impaired relaxation of cerebral arteries in the absence of elevated salt intake in normotensive congenic rats carrying the Dahl salt-sensitive renin gene.

Journal: American journal of physiology. Heart and circulatory physiology 20101201

Title: Epidermal growth factor receptor transactivation by endogenous vasoactive peptides contributes to hyperproliferation of vascular smooth muscle cells of SHR.

Journal: American journal of physiology. Heart and circulatory physiology 20101201

Title: Role of the organum vasculosum of the lamina terminalis for the chronic cardiovascular effects produced by endogenous and exogenous ANG II in conscious rats.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20101201

Title: Effects of angiotensin III on protein, DNA, and collagen synthesis of neonatal cardiomyocytes and cardiac fibroblasts in vitro.

Journal: Journal of cardiovascular pharmacology and therapeutics 20101201

Title: Similar renoprotection after renin-angiotensin-dependent and -independent antihypertensive therapy in 5/6-nephrectomized Ren-2 transgenic rats: are there blood pressure-independent effects?

Journal: Clinical and experimental pharmacology & physiology 20101201

Title: Targeted disruption of guanylyl cyclase-A/natriuretic peptide receptor-A gene provokes renal fibrosis and remodeling in null mutant mice: role of proinflammatory cytokines.

Journal: Endocrinology 20101201

Title: Comparison of angiotensin II type 1-receptor blockers to regress pressure overload-induced cardiac hypertrophy in mice.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20101201

Title: Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction.

Journal: Nature genetics 20101201

Title: Drug-drug interactions that reduce the formation of pharmacologically active metabolites: a poorly understood problem in clinical practice.

Journal: Journal of internal medicine 20101201

Title: Exercise and type 2 diabetes: the American College of Sports Medicine and the American Diabetes Association: joint position statement.

Journal: Diabetes care 20101201

Title: Exercise and type 2 diabetes: the American College of Sports Medicine and the American Diabetes Association: joint position statement executive summary.

Journal: Diabetes care 20101201

Title: Resistant hypertension responding to change from furosemide to thiazide: understanding calcium channel blocker-related edema.

Journal: Journal of clinical hypertension (Greenwich, Conn.) 20101201

Title: Distinct effects of intravascular and extravascular angiotensin II on cerebrovascular circulation of newborn pigs.

Journal: Experimental biology and medicine (Maywood, N.J.) 20101201

Title: [Pharmacokinetic drug interactions by herbal drugs: Critical evaluation and clinical relevance].

Journal: Wiener medizinische Wochenschrift (1946) 20101201

Title: Effect of Lacidipine on Blood Pressure and Endothelial Function in Mild-to-Moderate Essential Hypertension Patients With Diabetes in Korea.

Journal: Korean circulation journal 20101201

Title: Development of a list of potentially inappropriate drugs for the korean elderly using the delphi method.

Journal: Healthcare informatics research 20101201

Title: Left atrial and left atrial appendage systolic function in patients with post-myocardial distal blocks.

Journal: Archives of medical science : AMS 20101201

Title: Adducin- and ouabain-related gene variants predict the antihypertensive activity of rostafuroxin, part 2: clinical studies.

Journal: Science translational medicine 20101124

Title: Nox2 NADPH oxidase promotes pathologic cardiac remodeling associated with Doxorubicin chemotherapy.

Journal: Cancer research 20101115

Title: Combined effect of polarity and pH on the chromatographic behavior of some angiotensin II receptor antagonists and optimization of their determination in pharmaceutical dosage forms.

Journal: Journal of pharmaceutical and biomedical analysis 20101102

Title: [Effect of telmisartan on tubulointerstitial injury and expression of PPARγ in rat renal tissue of IgA nephropathy model].

Journal: Zhonghua yi xue za zhi 20101102

Title: A 52-week prospective, cohort study of the effects of losartan with or without hydrochlorothiazide (HCTZ) in hypertensive patients with metabolic syndrome.

Journal: Journal of human hypertension 20101101

Title: Telmisartan regresses left ventricular hypertrophy in caveolin-1-deficient mice.

Journal: Laboratory investigation; a journal of technical methods and pathology 20101101

Title: Angiotensin II inhibits the electrogenic Na+/HCO3- cotransport of cat cardiac myocytes.

Journal: Journal of molecular and cellular cardiology 20101101

Title: Impact of baseline renal function on the efficacy and safety of aliskiren added to losartan in patients with type 2 diabetes and nephropathy.

Journal: Diabetes care 20101101

Title: Adenoviral inhibition of AT1a receptors in the paraventricular nucleus inhibits acute increases in mean arterial blood pressure in the rat.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20101101

Title: Obesity-related cardiovascular risk factors after weight loss: a clinical trial comparing gastric bypass surgery and intensive lifestyle intervention.

Journal: European journal of endocrinology 20101101

Title: The role of blood pressure variability in the development of nephropathy in type 1 diabetes.

Journal: Diabetes care 20101101

Title: The role of renin-angiotensin agents in altering the natural history of type 2 diabetes mellitus.

Journal: Current cardiology reports 20101101

Title: Nuclear angiotensin-(1-7) receptor is functionally coupled to the formation of nitric oxide.

Journal: American journal of physiology. Renal physiology 20101101

Title: Evaluating 24-h antihypertensive efficacy by the smoothness index: a meta-analysis of an ambulatory blood pressure monitoring database.

Journal: Journal of hypertension 20101101

Title: Different effects of aliskiren and losartan on fibrinolysis and insulin sensitivity in hypertensive patients with metabolic syndrome.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20101101

Title: Addition of losartan to angiotensin-converting enzyme inhibitors improves insulin resistance in patients with chronic heart failure treated without β-blockers.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20101101

Title: Impaired flow-induced dilation of coronary arterioles of dogs fed a low-salt diet: roles of ANG II, PKC, and NAD(P)H oxidase.

Journal: American journal of physiology. Heart and circulatory physiology 20101101

Title: CYP4A2-induced hypertension is 20-hydroxyeicosatetraenoic acid- and angiotensin II-dependent.

Journal: Hypertension (Dallas, Tex. : 1979) 20101101

Title: Hypothalamic SOCS-3 expression and the effect of intracerebroventricular angiotensin II injection on water intake and renal sodium handling in SHR.

Journal: The journal of physiological sciences : JPS 20101101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Immobilization stress induces endothelial dysfunction by oxidative stress via the activation of the angiotensin II/its type I receptor pathway.

Journal: Atherosclerosis 20101101

Title: Inhibition of renin-angiotensin system affects prognosis of advanced pancreatic cancer receiving gemcitabine.

Journal: British journal of cancer 20101101

Title: [Role of angiontensin receptors in remodeling perivascular nerves].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20101101

Title: Angiotensin-2 receptors (AT1-R and AT2-R), new prognostic factors for renal clear-cell carcinoma?

Journal: British journal of cancer 20101101

Title: Strategies for initial management of hypertension.

Journal: The Indian journal of medical research 20101101

Title: Congestive heart failure in Indians: how do we improve diagnosis & management?

Journal: The Indian journal of medical research 20101101

Title: Diabetes & coronary heart disease: current perspectives.

Journal: The Indian journal of medical research 20101101

Title: Effect of the AT₁ receptor antagonist losartan on diurnal variation in pain threshold in spontaneously hypertensive rats.

Journal: Methods and findings in experimental and clinical pharmacology 20101101

Title: [Effect of Qindan Capsule on expression of vascular adventitial collagen I and III in old spontaneous hypertensive rats].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20101101

Title: Role of differential signaling pathways and oxidative stress in diabetic cardiomyopathy.

Journal: Current cardiology reviews 20101101

Title: Modulation of Gi Proteins in Hypertension: Role of Angiotensin II and Oxidative Stress.

Journal: Current cardiology reviews 20101101

Title: Aliskiren: a review of its use as monotherapy and as combination therapy in the management of hypertension.

Journal: Drugs 20101022

Title: CORD: COmparison of Recommended Doses of ace inhibitors and angiotensin II receptor blockers.

Journal: International journal of cardiology 20101008

Title: Erythropoietin is reduced by combination of diuretic therapy and RAAS blockade in proteinuric renal patients with preserved renal function.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20101001

Title: Angiotensin II/angiotensin II type I receptor (AT1R) signaling promotes MCF-7 breast cancer cells survival via PI3-kinase/Akt pathway.

Journal: Journal of cellular physiology 20101001

Title: Dapagliflozin monotherapy in type 2 diabetic patients with inadequate glycemic control by diet and exercise: a randomized, double-blind, placebo-controlled, phase 3 trial.

Journal: Diabetes care 20101001

Title: Interactions among related genes of renin-angiotensin system associated with type 2 diabetes.

Journal: Diabetes care 20101001

Title: Angiotensin-(1-7) and low-dose angiotensin II infusion reverse salt-induced endothelial dysfunction via different mechanisms in rat middle cerebral arteries.

Journal: American journal of physiology. Heart and circulatory physiology 20101001

Title: Exercise training combined with angiotensin II receptor blockade reduces oxidative stress after myocardial infarction in rats.

Journal: Experimental physiology 20101001

Title: Persistent antihypertensive effect of aliskiren is accompanied by reduced proteinuria and normalization of glomerular area in Ren-2 transgenic rats.

Journal: American journal of physiology. Renal physiology 20101001

Title: A small difference in the molecular structure of angiotensin II receptor blockers induces AT₁ receptor-dependent and -independent beneficial effects.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20101001

Title: Blockade of endothelial-mesenchymal transition by a Smad3 inhibitor delays the early development of streptozotocin-induced diabetic nephropathy.

Journal: Diabetes 20101001

Title: Is the presence of microalbuminuria a relevant marker of kidney disease?

Journal: Current hypertension reports 20101001

Title: Angiotensin II enhances connecting tubule glomerular feedback.

Journal: Hypertension (Dallas, Tex. : 1979) 20101001

Title: Moment-to-moment characteristics of the relationship between arterial pressure and renal interstitial hydrostatic pressure.

Journal: Hypertension (Dallas, Tex. : 1979) 20101001

Title: Antihypertensive and antiarrhythmic properties of a para-hydroxy[bis(ortho-morpholinylmethyl)]phenyl-1,4-DHP compound: comparison with other compounds of the same kind and relationship with logP values.

Journal: European journal of medicinal chemistry 20101001

Title: Role of the second disulfide bridge (Cys(18)-Cys(274)) in stabilizing the inactive AT₁ receptor.

Journal: Biological chemistry 20101001

Title: Cardiac fibrosis in mice with hypertrophic cardiomyopathy is mediated by non-myocyte proliferation and requires Tgf-β.

Journal: The Journal of clinical investigation 20101001

Title: Prognostic significance of left ventricular diastolic dysfunction in patients with left ventricular hypertrophy and systemic hypertension (the LIFE Study).

Journal: The American journal of cardiology 20101001

Title: The effect of anti-hypertensive drugs on the obstructive pancreatitis in rats.

Journal: Acta cirurgica brasileira 20101001

Title: Use of a tunneling technique to achieve a lower defibrillation threshold during implantable cardioverter defibrillator implantation via the right subclavian vein.

Journal: Journal of Korean medical science 20101001

Title: Increasing the doses of both diuretics and angiotensin receptor blockers is beneficial in subjects with uncontrolled systolic hypertension.

Journal: The Canadian journal of cardiology 20101001

Title: Losartan Inhibits Vascular Smooth Muscle Cell Proliferation through Activation of AMP-Activated Protein Kinase.

Journal: The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20101001

Title: Paraganglioma--a case of secondary hypertension.

Journal: Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 20101001

Title: Ninety-seven Years Old Hispanic Male With Mantle Cell Lymphoma.

Journal: Journal of clinical medicine research 20101001

Title: Angiotensin II type 1 receptor-dependent oxidative stress mediates endothelial dysfunction in type 2 diabetic mice.

Journal: Antioxidants & redox signaling 20100915

Title: Superoxide scavenging in the rostral ventrolateral medulla blunts the pressor response to peripheral chemoreflex activation.

Journal: Brain research 20100910

Title: Comparison of the influence of angiotensin-converting enzyme inhibitor lisinopril and angiotensin II receptor antagonist losartan in patients with idiopathic membranous nephropathy and nephrotic syndrome.

Journal: Scandinavian journal of urology and nephrology 20100901

Title: Mechanisms underlying the losartan treatment-induced improvement in the endothelial dysfunction seen in mesenteric arteries from type 2 diabetic rats.

Journal: Pharmacological research 20100901

Title: Haemochromatosis genotype and iron overload: association with hypertension and left ventricular hypertrophy.

Journal: Journal of internal medicine 20100901

Title: Simvastatin reduces pressor response to centrally administered angiotensin II.

Journal: American journal of hypertension 20100901

Title: Effects of the angiotensin II receptor blocker losartan on the monocyte expression of biglycan in hypertensive patients.

Journal: Clinical and experimental pharmacology & physiology 20100901

Title: Angiotensin II induces C-reactive protein expression through ERK1/2 and JNK signaling in human aortic endothelial cells.

Journal: Atherosclerosis 20100901

Title: Interaction between vasopressin and angiotensin II in vivo and in vitro: effect on aquaporins and urine concentration.

Journal: American journal of physiology. Renal physiology 20100901

Title: Angiotensin AT1 receptor activation mediates high glucose-induced epithelial-mesenchymal transition in renal proximal tubular cells.

Journal: Clinical and experimental pharmacology & physiology 20100901

Title: All-cause and cardiovascular mortality in relation to changing heart rate during treatment of hypertensive patients with electrocardiographic left ventricular hypertrophy.

Journal: European heart journal 20100901

Title: An efficient synthesis of a rationally designed 1,5 disubstituted imidazole AT(1) angiotensin II receptor antagonist: reorientation of imidazole pharmacophore groups in losartan reserves high receptor affinity and confirms docking studies.

Journal: Journal of computer-aided molecular design 20100901

Title: Intermittent hypoxia increases arterial blood pressure in humans through a Renin-Angiotensin system-dependent mechanism.

Journal: Hypertension (Dallas, Tex. : 1979) 20100901

Title: Clinically significant CYP2C inhibition by noscapine but not by glucosamine.

Journal: Clinical pharmacology and therapeutics 20100901

Title: Chart review of patients on valsartan-based single-pill combinations vs. ARB-based free combinations for BP goal achievement.

Journal: Current medical research and opinion 20100901

Title: Postmenopausal hypertension: role of the Renin-Angiotensin system.

Journal: Hypertension (Dallas, Tex. : 1979) 20100901

Title: Losartan reduces mortality in a genetic model of heart failure.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20100901

Title: Effectiveness, safety and cost of drug substitution in hypertension.

Journal: British journal of clinical pharmacology 20100901

Title: Resveratrol modulates drug- and carcinogen-metabolizing enzymes in a healthy volunteer study.

Journal: Cancer prevention research (Philadelphia, Pa.) 20100901

Title: Angiotensin receptor type 1 antagonists protect against neuronal injury induced by oxygen-glucose depletion.

Journal: British journal of pharmacology 20100901

Title: [Regeneration of perivascular nerve and role of angiotensin receptors].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20100901

Title: TGF-β signaling in aortic aneurysm: another round of controversy.

Journal: Journal of genetics and genomics = Yi chuan xue bao 20100901

Title: Pharmacokinetics of a losartan potassium released from a transdermal therapeutic system for the treatment of hypertension.

Journal: Die Pharmazie 20100901

Title: How to avoid discontinuation of antihypertensive treatment: The experience in São Paulo, Brazil.

Journal: Clinics (Sao Paulo, Brazil) 20100901

Title: Acquired factor VIII deficiency after consuming the dried gallbladder of a cobra, Naja naja.

Journal: The Korean journal of hematology 20100901

Title: [The normalized smoothness index and parametric population RDH index of losartan in patients with newly diagnosed hypertension and metabolic syndrome].

Journal: Vnitrni lekarstvi 20100901

Title: [The HEAAL study].

Journal: Giornale italiano di cardiologia (2006) 20100901

Title: In dystrophic hamsters losartan affects control of ventilation and dopamine D1 receptor density.

Journal: Respiratory physiology & neurobiology 20100831

Title: Effects of coenzyme Q10 supplementation on activities of selected antioxidative enzymes and lipid peroxidation in hypertensive patients treated with indapamide. A pilot study.

Journal: Archives of medical science : AMS 20100830

Title: Angiotensin AT1 receptor antagonists enhance the anticonvulsant action of valproate in the mouse model of maximal electroshock.

Journal: European journal of pharmacology 20100825

Title: Inhibition of the renin-angiotensin system prevents seizures in a rat model of epilepsy.

Journal: Clinical science (London, England : 1979) 20100817

Title: Characterization of new PPARgamma agonists: benzimidazole derivatives-importance of positions 5 and 6, and computational studies on the binding mode.

Journal: Bioorganic & medicinal chemistry 20100815

Title: Comparison of the efficacy of candesartan and losartan: a meta-analysis of trials in the treatment of hypertension.

Journal: Journal of human hypertension 20100801

Title: Central fatigue induced by losartan involves brain serotonin and dopamine content.

Journal: Medicine and science in sports and exercise 20100801

Title: Effectiveness of combination of losartan potassium and doxycycline versus single-drug treatments in the secondary prevention of thoracic aortic aneurysm in Marfan syndrome.

Journal: The Journal of thoracic and cardiovascular surgery 20100801

Title: Astroglia are a possible cellular substrate of angiotensin(1-7) effects in the rostral ventrolateral medulla.

Journal: Cardiovascular research 20100801

Title: Fluconazole-induced intoxication with phenytoin in a patient with ultra-high activity of CYP2C9.

Journal: European journal of clinical pharmacology 20100801

Title: Serum uric acid is associated with new-onset diabetes in hypertensive patients with left ventricular hypertrophy: The LIFE Study.

Journal: American journal of hypertension 20100801

Title: Reduction of fibrosis-related arrhythmias by chronic renin-angiotensin-aldosterone system inhibitors in an aged mouse model.

Journal: American journal of physiology. Heart and circulatory physiology 20100801

Title: Angiotensin II-induced reduction in body mass is Ang II receptor mediated in association with elevated corticosterone.

Journal: Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 20100801

Title: Angiotensin II induces hyperresponsiveness of bronchial smooth muscle via an activation of p42/44 ERK in rats.

Journal: Pflugers Archiv : European journal of physiology 20100801

Title: Losartan: the dose does it.

Journal: Expert opinion on pharmacotherapy 20100801

Title: Low dose of telmisartan prevents ischemic brain damage with peroxisome proliferator-activated receptor-gamma activation in diabetic mice.

Journal: Journal of hypertension 20100801

Title: Losartan inhibits LPS-induced inflammatory signaling through a PPARgamma-dependent mechanism in human THP-1 macrophages.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20100801

Title: Regulation of the renin expression in the retinal pigment epithelium by systemic stimuli.

Journal: American journal of physiology. Renal physiology 20100801

Title: The impact of ANG II and IV on INS-1 cells and on blood glucose and plasma insulin.

Journal: Journal of receptor and signal transduction research 20100801

Title: A low concentration of ouabain (0.18 microg/kg) enhances hypertension in spontaneously hypertensive rats by inhibiting the Na+ pump and activating the renin-angiotensin system.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20100801

Title: Therapeutic effects of vitamin D analogs on cardiac hypertrophy in spontaneously hypertensive rats.

Journal: The American journal of pathology 20100801

Title: Comparison of different measures of urinary protein excretion for prediction of renal events.

Journal: Journal of the American Society of Nephrology : JASN 20100801

Title: Cost-effectiveness of interventions to prevent and control diabetes mellitus: a systematic review.

Journal: Diabetes care 20100801

Title: Are individuals with diabetes seeing better?: a long-term epidemiological perspective.

Journal: Diabetes 20100801

Title: Losartan associated anaphylaxis and angioneurotic oedema.

Journal: JPMA. The Journal of the Pakistan Medical Association 20100801

Title: Losartan attenuates vascular remodeling of the aorta in spontaneously hypertensive rats and the underlying mechanism.

Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20100801

Title: Successful Percutaneous Renal Artery Angioplasty and Stenting for Acute Oliguric Renal Failure in a Solitary Functioning Kidney Caused by Takayasu's Arteritis.

Journal: Korean circulation journal 20100801

Title: [Aortic pulse wave velocity in patients with metabolic syndrome and hypertension treated with sartans].

Journal: Vnitrni lekarstvi 20100801

Title: Losartan and hypertensive children. Another option for a small number of children.

Journal: Prescrire international 20100801

Title: [Effect of treatment of non-nephrotic syndrome IgA nephropathy with Shenyanning].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20100801

Title: [Active pharmacosurveillance of patients affiliated to the Colombian general social security/health system].

Journal: Revista de salud publica (Bogota, Colombia) 20100801

Title: A gene on the HER2 amplicon, C35, is an oncogene in breast cancer whose actions are prevented by inhibition of Syk.

Journal: British journal of cancer 20100727

Title: Antihypertensive activity of Salvia elegans Vahl. (Lamiaceae): ACE inhibition and angiotensin II antagonism.

Journal: Journal of ethnopharmacology 20100720

Title: A consistency-adjusted alpha-adaptive strategy for sequential testing.

Journal: Statistics in medicine 20100710

Title: Inhibition of renin-angiotensin system in experimental acute pancreatitis in rats: a new therapeutic target?

Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20100701

Title: Blocking angiotensin II Type 1 receptor triggers apoptotic cell death in human pancreatic cancer cells.

Journal: Pancreas 20100701

Title: Losartan improved respiratory function and coenzyme Q content in brain mitochondria of young spontaneously hypertensive rats.

Journal: Cellular and molecular neurobiology 20100701

Title: Different protective actions of losartan and tempol on the renal inflammatory response to acute sodium overload.

Journal: Journal of cellular physiology 20100701

Title: The renin-angiotensin system mediates hyperoxia-induced collagen production in human lung fibroblasts.

Journal: Free radical biology & medicine 20100701

Title: Upregulation of AT1R and iNOS in the rostral ventrolateral medulla (RVLM) is essential for the sympathetic hyperactivity and hypertension in the 2K-1C Wistar rat model.

Journal: American journal of hypertension 20100701

Title: Aliskiren enhances protective effects of valsartan against type 2 diabetic nephropathy in mice.

Journal: Journal of hypertension 20100701

Title: Greater regression of electrocardiographic left ventricular hypertrophy during hydrochlorothiazide therapy in hypertensive patients.

Journal: American journal of hypertension 20100701

Title: In-treatment midwall and endocardial fractional shortening predict cardiovascular outcome in hypertensive patients with preserved baseline systolic ventricular function: the Losartan Intervention For Endpoint reduction study.

Journal: Journal of hypertension 20100701

Title: Angiotensin II signaling through the AT1a and AT1b receptors does not have a role in the development of cerulein-induced chronic pancreatitis in the mouse.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20100701

Title: RAAS blockade in combination with diuretic therapy increases urine excretion, which in turn increases drinking and thus reduces erythropoietin and proteinuria.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100701

Title: Sirolimus and everolimus reduce albumin endocytosis in proximal tubule cells via an angiotensin II-dependent pathway.

Journal: Transplant immunology 20100701

Title: Soluble uric acid increases intracellular calcium through an angiotensin II-dependent mechanism in immortalized human mesangial cells.

Journal: Experimental biology and medicine (Maywood, N.J.) 20100701

Title: Is hydrochlorothiazide more effective on LVH in nonresponders to losartan than in those to atenolol?

Journal: American journal of hypertension 20100701

Title: Marfan syndrome and focal segmental glomerulosclerosis: a novel association.

Journal: Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20100701

Title: Relationship of left atrial enlargement to persistence or development of ECG left ventricular hypertrophy in hypertensive patients: implications for the development of new atrial fibrillation.

Journal: Journal of hypertension 20100701

Title: Angiotensin-converting enzyme inhibitors and angioedema.

Journal: Allergy, asthma & immunology research 20100701

Title: Blood pressure and medication during long-term antihypertensive therapy based on morning home SBP in hypertensive patients: Hypertension Control Based on Home Systolic Pressure (HOSP) substudy.

Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20100701

Title: The antioxidant effect of angiotensin II receptor blocker, losartan, in streptozotocin-induced diabetic rats.

Journal: Translational research : the journal of laboratory and clinical medicine 20100701

Title: Effects of myricetin, an antioxidant, on the pharmacokinetics of losartan and its active metabolite, EXP-3174, in rats: possible role of cytochrome P450 3A4, cytochrome P450 2C9 and P-glycoprotein inhibition by myricetin.

Journal: The Journal of pharmacy and pharmacology 20100701

Title: Anti-hypertensive drugs have different effects on ventricular hypertrophy regression.

Journal: Clinics (Sao Paulo, Brazil) 20100701

Title: Effectiveness of barnidipine 10 or 20 mg plus losartan 50-mg combination versus losartan 100-mg monotherapy in patients with essential hypertension not controlled by losartan 50-mg monotherapy: A 12-week, multicenter, randomized, open-label, parallel-group study.

Journal: Clinical therapeutics 20100701

Title: Pharmacokinetics and bioequivalence evaluation of two losartan potassium 50-mg tablets: A single-dose, randomized-sequence, open-label, two-way crossover study in healthy Chinese male volunteers.

Journal: Clinical therapeutics 20100701

Title: Fixed-dose telmisartan/hydrochlorothiazide in comparison with losartan/hydrochlorothiazide in decreasing serum hepatocyte growth factor and improving endothelial dysfunction in hypertensive patients.

Journal: International heart journal 20100701

Title: Generic ARBs are coming.

Journal: Harvard heart letter : from Harvard Medical School 20100701

Title: Mechanical stress-evoked but angiotensin II-independent activation of angiotensin II type 1 receptor induces cardiac hypertrophy through calcineurin pathway.

Journal: Biochemical and biophysical research communications 20100625

Title: Mechanical stretch induces nerve sprouting in rat sympathetic neurocytes.

Journal: Autonomic neuroscience : basic & clinical 20100624

Title: Angiotensin II and the ERK pathway mediate the induction of myocardin by hypoxia in cultured rat neonatal cardiomyocytes.

Journal: Clinical science (London, England : 1979) 20100622

Title: Management of varices in cirrhosis.

Journal: The New England journal of medicine 20100617

Title: Selective angiotensin II AT(2) receptor agonists with reduced CYP 450 inhibition.

Journal: Bioorganic & medicinal chemistry 20100615

Title: Hypercholesterolemia modifies angiotensin II desensitisation and cross talk between alpha(1)-adrenoceptor and angiotensin AT(1) receptor in rabbit aorta.

Journal: European journal of pharmacology 20100610

Title: Transforming growth factor beta1 mediates apoptotic activity of angiotensin II type I receptor blocker on prostate epithelium in vitro.

Journal: The Prostate 20100601

Title: Combined vitamin D analog and AT1 receptor antagonist synergistically block the development of kidney disease in a model of type 2 diabetes.

Journal: Kidney international 20100601

Title: Repeated administration of angiotensin II reduces its dipsogenic effect without affecting saline intake.

Journal: Experimental physiology 20100601

Title: Hypertensive effects of central angiotensin II infusion and restraint stress are reduced with age.

Journal: Journal of hypertension 20100601

Title: Effect of ACE2 and angiotensin-(1-7) in a mouse model of early chronic kidney disease.

Journal: American journal of physiology. Renal physiology 20100601

Title: Hypertension study in anaesthetized rabbits: protocol proposal for AT1 antagonists screening.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20100601

Title: Economic evaluation of four angiotensin II receptor blockers in the treatment of hypertension.

Journal: Current medical research and opinion 20100601

Title: Vitamin D receptor attenuates renal fibrosis by suppressing the renin-angiotensin system.

Journal: Journal of the American Society of Nephrology : JASN 20100601

Title: Hotline update of clinical trials and registries presented at the American College of Cardiology Congress 2010: ACCORD, INVEST, NAVIGATOR, RACE II, SORT OUT III, CSP-474, DOSE, ASPIRE and more.

Journal: Clinical research in cardiology : official journal of the German Cardiac Society 20100601

Title: Upregulation of renal sodium transporters in D5 dopamine receptor-deficient mice.

Journal: Hypertension (Dallas, Tex. : 1979) 20100601

Title: Lack of regression of left ventricular hypertrophy is associated with higher incidence of revascularization in hypertension: The LIFE Study.

Journal: Blood pressure 20100601

Title: A single-nucleotide polymorphism of alanine to threonine at position 163 of the human angiotensin II type 1 receptor impairs Losartan affinity.

Journal: Pharmacogenetics and genomics 20100601

Title: In-treatment reduced left atrial diameter during antihypertensive treatment is associated with reduced new-onset atrial fibrillation in hypertensive patients with left ventricular hypertrophy: The LIFE Study.

Journal: Blood pressure 20100601

Title: Reduction of inducible nitric oxide synthase via angiotensin receptor blocker prevents the oxidative retinal damage in diabetic hypertensive rats.

Journal: Current eye research 20100601

Title: Are vitamin D receptor agonists like angiotensin-converting enzyme inhibitors without side effects?

Journal: Kidney international 20100601

Title: Are coronary revascularization and myocardial infarction a homogeneous combined endpoint in hypertension trials? The Losartan Intervention For Endpoint reduction in hypertension study.

Journal: Journal of hypertension 20100601

Title: Ambulatory monitoring of systolic hypertension in the elderly: Eprosartan/hydrochlorothiazide compared with losartan/hydrochlorothiazide (INSIST trial).

Journal: Advances in therapy 20100601

Title: Angiotensin-(1-9), the product of angiotensin I conversion in platelets, enhances arterial thrombosis in rats.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20100601

Title: Norepinephrine remains increased in the six-minute walking test after heart transplantation.

Journal: Clinics (Sao Paulo, Brazil) 20100601

Title: Effects of Huanshuai Recipe Oral Liquid on restructuring glomerular microvasculature and expression of vascular endothelial growth factor in subtotal nephrectomized rats.

Journal: Chinese journal of integrative medicine 20100601

Title: Comparison of the efficacy and tolerability of telmisartan and enalapril in patients of mild to moderate essential hypertension.

Journal: Indian journal of pharmacology 20100601

Title: Marfan syndrome: clinical manifestations, pathophysiology and new outlook on drug therapy.

Journal: Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 20100601

Title: Simultaneous spectrophotometric determination of losartan potassium, amlodipine besilate and hydrochlorothiazide in pharmaceuticals by chemometric methods.

Journal: Acta pharmaceutica (Zagreb, Croatia) 20100601

Title: Ambulatory blood pressure, endothelial perturbation, and microvascular complications in type 2 diabetes.

Journal: Danish medical bulletin 20100601

Title: Losartan attenuates chronic cigarette smoke exposure-induced pulmonary arterial hypertension in rats: possible involvement of angiotensin-converting enzyme-2.

Journal: Toxicology and applied pharmacology 20100515

Title: Renin-Angiotensin system blockade for diabetic nephropathy prevention.

Journal: The American journal of cardiology 20100515

Title: Angiotensin II stimulates thick ascending limb NO production via AT(2) receptors and Akt1-dependent nitric-oxide synthase 3 (NOS3) activation.

Journal: The Journal of biological chemistry 20100514

Title: Prostaglandin E1 for preventing the progression of diabetic kidney disease.

Journal: The Cochrane database of systematic reviews 20100512

Title: Inhibition of angiotensin II receptor 1 limits tumor-associated angiogenesis and attenuates growth of murine melanoma.

Journal: Cancer chemotherapy and pharmacology 20100501

Title: Determination of asperosaponin VI in rat plasma by HPLC-ESI-MS and its application to preliminary pharmacokinetic studies.

Journal: Biomedical chromatography : BMC 20100501

Title: Angiotensin II up-regulates CX3CR1 expression in THP-1 monocytes: impact on vascular inflammation and atherogenesis.

Journal: Journal of thrombosis and thrombolysis 20100501

Title: Long-term metabolic effects of different doses of niacin-bound chromium on Sprague-Dawley rats.

Journal: Molecular and cellular biochemistry 20100501

Title: Tumour necrosis factor-like weak inducer of apoptosis (TWEAK) and its receptor Fn14 during cardiac remodelling in rats.

Journal: Acta physiologica (Oxford, England) 20100501

Title: Fibronectin synthesis by high glucose level mediated proliferation of mouse embryonic stem cells: Involvement of ANG II and TGF-beta1.

Journal: Journal of cellular physiology 20100501

Title: Chronic AT1 receptor blockade normalizes NMDA-mediated changes in renal sympathetic nerve activity and NR1 expression within the PVN in rats with heart failure.

Journal: American journal of physiology. Heart and circulatory physiology 20100501

Title: Is pulse pressure a predictor of new-onset diabetes in high-risk hypertensive patients?: a subanalysis of the Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J) trial.

Journal: Diabetes care 20100501

Title: Involvement of the renin-angiotensin system in the development of vascular damage in a rat model of arthritis: effect of angiotensin receptor blockers.

Journal: Arthritis and rheumatism 20100501

Title: Losartan increases NO release in afferent arterioles during regression of L-NAME-induced renal damage.

Journal: American journal of physiology. Renal physiology 20100501

Title: Does enhanced respiratory-sympathetic coupling contribute to peripheral neural mechanisms of angiotensin II-salt hypertension?

Journal: Experimental physiology 20100501

Title: Ventilator-induced inflammatory response in lipopolysaccharide-exposed rat lung is mediated by angiotensin-converting enzyme.

Journal: The American journal of pathology 20100501

Title: Marfan syndrome. Part 2: treatment and management of patients.

Journal: Nature reviews. Cardiology 20100501

Title: Aldose reductase inhibitor ameliorates renal vascular endothelial growth factor expression in streptozotocin-induced diabetic rats.

Journal: Yonsei medical journal 20100501

Title: Soluble epoxide hydrolase in atherosclerosis.

Journal: Current atherosclerosis reports 20100501

Title: Is losartan the true panacea for aneurysm disease? PRO.

Journal: Cardiology clinics 20100501

Title: Is losartan the true panacea for aneurysm disease? CON.

Journal: Cardiology clinics 20100501

Title: Editorial comment: losartan-based medical therapy for aneurysm disease.

Journal: Cardiology clinics 20100501

Title: The effects of lumiracoxib 100 mg once daily vs. ibuprofen 600 mg three times daily on the blood pressure profiles of hypertensive osteoarthritis patients taking different classes of antihypertensive agents.

Journal: International journal of clinical practice 20100501

Title: Comparing angiotensin II receptor blockers on benefits beyond blood pressure.

Journal: Advances in therapy 20100501

Title: Rationale and design of a randomized clinical trial (Marfan Sartan) of angiotensin II receptor blocker therapy versus placebo in individuals with Marfan syndrome.

Journal: Archives of cardiovascular diseases 20100501

Title: Diabetic nephropathy and chronic kidney disease at a busy diabetes clinic: a study of outpatient care and suggestions for improved care pathways at a subspecialty specialist diabetic renal clinic.

Journal: The Ulster medical journal 20100501

Title: The Role of Asymmetric Dimethylarginine (ADMA) in Endothelial Dysfunction and Cardiovascular Disease.

Journal: Current cardiology reviews 20100501

Title: Chronic intermittent hypoxia augments chemoreflex control of sympathetic activity: role of the angiotensin II type 1 receptor.

Journal: Respiratory physiology & neurobiology 20100415

Title: Effects of atenolol or losartan on fibrinolysis and von Willebrand factor in hypertensive patients with left ventricular hypertrophy.

Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20100401

Title: Recoverability of renal function after relief of chronic partial unilateral ureteral obstruction: study of the effect of angiotensin receptor blocker (losartan).

Journal: Urology 20100401

Title: Losartan prevents portal hypertension-induced, redox-mediated endothelial dysfunction in the mesenteric artery in rats.

Journal: Gastroenterology 20100401

Title: Effects of losartan vs candesartan in reducing cardiovascular events in the primary treatment of hypertension.

Journal: Journal of human hypertension 20100401

Title: Sympathoinhibitory effect of statins in chronic heart failure.

Journal: Clinical autonomic research : official journal of the Clinical Autonomic Research Society 20100401

Title: Short-term angiotensin-1 receptor antagonism in type 2 diabetic Goto-Kakizaki rats normalizes endothelin-1-induced mesenteric artery contraction.

Journal: Peptides 20100401

Title: One-year effectiveness and safety of open-label losartan/hydrochlorothiazide combination therapy in Japanese patients with hypertension uncontrolled with ARBs or ACE inhibitors.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20100401

Title: Effect of Renin-Angiotensin system blockade on insulin resistance and inflammatory parameters in patients with impaired glucose tolerance.

Journal: Diabetes care 20100401

Title: Heart failure events with rosiglitazone in type 2 diabetes: data from the RECORD clinical trial.

Journal: European heart journal 20100401

Title: Antiapoptotic effect of angiotensin-II type-1 receptor blockade in renal tubular cells of hyperoxaluric rats.

Journal: Urological research 20100401

Title: Angiotensin-(1-7) and angiotension II in the rostral ventrolateral medulla modulate the cardiac sympathetic afferent reflex and sympathetic activity in rats.

Journal: Pflugers Archiv : European journal of physiology 20100401

Title: Telmisartan prevents weight gain and obesity through activation of peroxisome proliferator-activated receptor-delta-dependent pathways.

Journal: Hypertension (Dallas, Tex. : 1979) 20100401

Title: Pharmacodynamics of a losartan transdermal system for the treatment of hypertension.

Journal: Drug development and industrial pharmacy 20100401

Title: AT1 receptor blockade prevents the increase in blood pressure and the augmentation of intrarenal ANG II levels in hypertensive Cyp1a1-Ren2 transgenic rats fed with a high-salt diet.

Journal: The American journal of the medical sciences 20100401

Title: Serological predictors for the recurrence of atrial fibrillation after electrical cardioversion.

Journal: Korean circulation journal 20100401

Title: Enhanced effect of losartan and rosuvastatin on neointima hyperplasia.

Journal: Archives of pharmacal research 20100401

Title: Curcumin reduces angiotensin II-mediated cardiomyocyte growth via LOX-1 inhibition.

Journal: Journal of cardiovascular pharmacology 20100401

Title: Blockade of calcium channels and AT1 receptor prevents the hypertensive effect of calcilytic NPS 2143 in rats.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20100401

Title: Evidence for the involvement of NADPH oxidase in ischemia/reperfusion-induced gastric damage via angiotensin II.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20100401

Title: Utilization of cardiovascular drugs in Zagreb 2001-2005.

Journal: Acta cardiologica 20100401

Title: Angiotensin II type 1 receptor gene polymorphism could influence renoprotective response to losartan treatment in type 1 diabetic patients with high urinary albumin excretion rate.

Journal: Vojnosanitetski pregled 20100401

Title: Effects of mineralocorticoid and angiotensin II receptor blockers on proteinuria and glomerular podocyte protein expression in a model of minimal change nephrotic syndrome.

Journal: Nephrology (Carlton, Vic.) 20100401

Title: Establishment of an in vivo model facilitates B2 receptor protein maturation and heterodimerization.

Journal: Integrative biology : quantitative biosciences from nano to macro 20100401

Title: Application of direct renin inhibition to chronic kidney disease.

Journal: Cardiovascular drugs and therapy 20100401

Title: Comparative study of hydrochlorothiazide and indapamide on the anti-atherogenic potential of losartan in cholesterol fed rat.

Journal: Bangladesh Medical Research Council bulletin 20100401

Title: Importance of angiotensinergic mechanisms for the pressor response to l-glutamate into the rostral ventrolateral medulla.

Journal: Brain research 20100331

Title: FURO/CAP: a protocol for sodium intake sensitization.

Journal: Physiology & behavior 20100330

Title: High-dose versus low-dose losartan in patients with heart failure.

Journal: Lancet (London, England) 20100327

Title: High-dose versus low-dose losartan in patients with heart failure.

Journal: Lancet (London, England) 20100327

Title: Telmisartan improves vascular function independently of metabolic and antihypertensive effects in hypertensive subjects with impaired glucose tolerance.

Journal: International journal of cardiology 20100318

Title: Simultaneous determination of irbesartan and hydrochlorothiazide in human plasma using HPLC coupled with tandem mass spectrometry: Application to bioequivalence studies.

Journal: Journal of pharmaceutical and biomedical analysis 20100311

Title: Structural basis for platelet antiaggregation by angiotensin II type 1 receptor antagonist losartan (DuP-753) via glycoprotein VI.

Journal: Journal of medicinal chemistry 20100311

Title: Angiotensin II infusion promotes ascending aortic aneurysms: attenuation by CCR2 deficiency in apoE-/- mice.

Journal: Clinical science (London, England : 1979) 20100309

Title: Effect of acute stress on sexual behavior in female rats: participation of the central angiotensinergic system.

Journal: Behavioural brain research 20100305

Title: Angiotensin II inhibits neuronal nitric oxide synthase activation through the ERK1/2-RSK signaling pathway to modulate central control of blood pressure.

Journal: Circulation research 20100305

Title: Na(+)-ATPase in spontaneous hypertensive rats: possible AT(1) receptor target in the development of hypertension.

Journal: Biochimica et biophysica acta 20100301

Title: Two flavonolignans from milk thistle (Silybum marianum) inhibit CYP2C9-mediated warfarin metabolism at clinically achievable concentrations.

Journal: The Journal of pharmacology and experimental therapeutics 20100301

Title: Cardiovascular interactions between losartan and fructose in mice.

Journal: Journal of cardiovascular pharmacology and therapeutics 20100301

Title: Differences in pharmacology and their translation into differences in clinical efficacy--a comparison of the renin angiotensin blocking agents irbesartan and losartan.

Journal: Expert opinion on pharmacotherapy 20100301

Title: Angiotensin type 2 receptor actions contribute to angiotensin type 1 receptor blocker effects on kidney fibrosis.

Journal: American journal of physiology. Renal physiology 20100301

Title: Downregulated Kv4.3 expression in the RVLM as a potential mechanism for sympathoexcitation in rats with chronic heart failure.

Journal: American journal of physiology. Heart and circulatory physiology 20100301

Title: Reduction of advanced liver fibrosis by short-term targeted delivery of an angiotensin receptor blocker to hepatic stellate cells in rats.

Journal: Hepatology (Baltimore, Md.) 20100301

Title: Protection of retinal vasculature by losartan against apoptosis and vasculopathy in rats with spontaneous hypertension.

Journal: Journal of hypertension 20100301

Title: NOX2 is the primary source of angiotensin II-induced superoxide in the macula densa.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20100301

Title: Effects of the AT(1) receptor blocker losartan and the calcium channel blocker benidipine on the accumulation of lipids in the kidney of a rat model of metabolic syndrome.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20100301

Title: Randomized, double-blind, controlled study of losartan in children with proteinuria.

Journal: Clinical journal of the American Society of Nephrology : CJASN 20100301

Title: Alterations of cardiac ERK1/2 expression and activity due to volume overload were attenuated by the blockade of RAS.

Journal: Journal of cardiovascular pharmacology and therapeutics 20100301

Title: Receptor activity-modifying protein 1 increases baroreflex sensitivity and attenuates Angiotensin-induced hypertension.

Journal: Hypertension (Dallas, Tex. : 1979) 20100301

Title: Comparative vascular and renal tubular effects of angiotensin II receptor blockers combined with a thiazide diuretic in humans.

Journal: Journal of hypertension 20100301

Title: Year in review in Intensive Care Medicine 2009: II. Neurology, cardiovascular, experimental, pharmacology and sedation, communication and teaching.

Journal: Intensive care medicine 20100301

Title: Diabetes-associated alterations in volatile anesthetic actions on contractile response to norepinephrine in isolated mesenteric resistance arteries.

Journal: Anesthesiology 20100301

Title: Blood pressure and diabetic nephropathy.

Journal: Diabetes care 20100301

Title: Review of the AMADEO study: reducing proteinuria in patients with diabetic nephropathy with telmisartan versus losartan. Commentary.

Journal: Postgraduate medicine 20100301

Title: Where will the next generation of stroke treatments come from?

Journal: PLoS medicine 20100301

Title: Interaction of angiotensin receptor type 1 blockers with ATP-binding cassette transporters.

Journal: Biopharmaceutics & drug disposition 20100301

Title: [Effects of Shenqi Jiedu Decoction on expressions of transforming growth factor-beta1, smad2 and smad3 in renal tissues of rats with chronic renal failure induced by adenine].

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20100301

Title: Role of vasoactive peptides in high glucose-induced increased expression of Gαq/11 proteins and associated signaling in vascular smooth muscle cells.

Journal: Canadian journal of physiology and pharmacology 20100301

Title: Update on the pharmacological treatment of Alzheimer's disease.

Journal: Current neuropharmacology 20100301

Title: Recurrent syncope and hypocalcaemic cardiomyopathy as manifestations of Fahr's syndrome.

Journal: Archives of medical science : AMS 20100301

Title: Hypothyroid dependent myocardial angiotensin receptor trafficking is involved in improved cardiac performance after heat acclimation.

Journal: Life sciences 20100227

Title: Effects of anti-hypertensive drugs on esophageal body contraction.

Journal: World journal of gastroenterology 20100227

Title: The effect of Telmisartan on collagen biosynthesis depends on the status of estrogen activation in breast cancer cells.

Journal: European journal of pharmacology 20100225

Title: Angiotensin II induces a region-specific hyperplasia of the ascending aorta through regulation of inhibitor of differentiation 3.

Journal: Circulation research 20100219

Title: Angiotensin II type 2 receptor mediated angiotensin II and high glucose induced decrease in renal prorenin/renin receptor expression.

Journal: Molecular and cellular endocrinology 20100205

Title: Cost-effectiveness of antihypertensive treatment in patients 80 years of age or older in Switzerland: an analysis of the HYVET study from a Swiss perspective.

Journal: Journal of human hypertension 20100201

Title: Expression and distribution of NADPH oxidase isoforms in human myometrium--role in angiotensin II-induced hypertrophy.

Journal: Biology of reproduction 20100201

Title: Effect of direct renin inhibition on renal hemodynamic function, arterial stiffness, and endothelial function in humans with uncomplicated type 1 diabetes: a pilot study.

Journal: Diabetes care 20100201

Title: Angiotensin II exerts glucose-dependent effects on Kv currents in mouse pancreatic beta-cells via angiotensin II type 2 receptors.

Journal: American journal of physiology. Cell physiology 20100201

Title: Human recombinant ACE2 reduces the progression of diabetic nephropathy.

Journal: Diabetes 20100201

Title: Curcumin reduces angiotensin II-mediated cardiomyocyte growth via LOX-1 inhibition.

Journal: Journal of cardiovascular pharmacology 20100201

Title: Angiotensin II type 1 and type 2 receptors regulate basal skeletal muscle microvascular volume and glucose use.

Journal: Hypertension (Dallas, Tex. : 1979) 20100201

Title: Innovations in aortic disease: the ascending aorta and aortic arch.

Journal: Journal of cardiothoracic and vascular anesthesia 20100201

Title: Building a tiered approach to in vitro predictive toxicity screening: a focus on assays with in vivo relevance.

Journal: Combinatorial chemistry & high throughput screening 20100201

Title: Glutamatergic receptor activation in the rostral ventrolateral medulla mediates the sympathoexcitatory response to hyperinsulinemia.

Journal: Hypertension (Dallas, Tex. : 1979) 20100201

Title: Effect of ACE insertion/deletion and 12 other polymorphisms on clinical outcomes and response to treatment in the LIFE study.

Journal: Pharmacogenetics and genomics 20100201

Title: HEAAL: the final chapter in the story of angiotensin receptor blockers in heart failure--lessons learnt from a decade of trials.

Journal: European journal of heart failure 20100201

Title: Clinical trials update from the American Heart Association meeting 2009: HEAAL, FAIR-HF, J-CHF, HeartMate II, PACE and a meta-analysis of dose-ranging studies of beta-blockers in heart failure.

Journal: European journal of heart failure 20100201

Title: Relationship of blood pressure to retinal vessel diameter in type 1 diabetes mellitus.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20100201

Title: Comparative effects of losartan and nifedipine therapy on exercise capacity, Doppler echocardiographic parameters and endothelin levels in patients with secondary pulmonary hypertension.

Journal: Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20100201

Title: Losartan and nifedipine therapy in patients with secondary pulmonary hypertension.

Journal: Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20100201

Title: Effects of eprosartan on diastolic function and neurohormones in patients with hypertension and diastolic dysfunction.

Journal: Cardiovascular drugs and therapy 20100201

Title: Dual blockade of the renin-angiotensin-aldosterone system is safe and effective in reducing albuminuria in Asian type 2 diabetic patients with nephropathy.

Journal: Singapore medical journal 20100201

Title: Angiotensin II receptor blocker add-on therapy for low cardiac output in decompensated heart failure.

Journal: Arquivos brasileiros de cardiologia 20100201

Title: A case of losartan induced angioedema.

Journal: Indian journal of medical sciences 20100201

Title: Development of swelling/floating gastroretentive drug delivery system based on a combination of hydroxyethyl cellulose and sodium carboxymethyl cellulose for Losartan and its clinical relevance in healthy volunteers with CYP2C9 polymorphism.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100131

Title: TRPV1 gene deficiency attenuates miniature EPSC potentiation induced by mannitol and angiotensin II in supraoptic magnocellular neurons.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100120

Title: Mechanism of VEGF expression by high glucose in proximal tubule epithelial cells.

Journal: Molecular and cellular endocrinology 20100115

Title: Use of multiattribute utility theory for formulary management in a health system.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20100115

Title: Angiotensin II and CRF receptors in the central nucleus of the amygdala mediate hemodynamic response variability to cocaine in conscious rats.

Journal: Brain research 20100114

Title: Angiotensin II activates JAK2/STAT3 pathway and induces interleukin-6 production in cultured rat brainstem astrocytes.

Journal: Regulatory peptides 20100108

Title: Angiotensin II type 1 receptor-mediated upregulation of calcineurin activity underlies impairment of cardioprotective signaling in diabetic hearts.

Journal: Circulation research 20100108

Title: Are there effects of renin-angiotensin system antagonists beyond blood pressure control?

Journal: The American journal of cardiology 20100104

Title: Interaction of angiotensin II type 1 receptor blockers with P-gp substrates in Caco-2 cells and hMDR1-expressing membranes.

Journal: Life sciences 20100102

Title: Modulation of hepatic fibrosis by c-Jun-N-terminal kinase inhibition.

Journal: Gastroenterology 20100101

Title: Role of the median preoptic nucleus in the chronic hypotensive effect of losartan in sodium-replete normal rats.

Journal: Clinical and experimental pharmacology & physiology 20100101

Title: Angiotensin II signaling via type 2 receptors in a human model of vascular hyporeactivity: implications for hypertension.

Journal: Journal of hypertension 20100101

Title: Angiotensin II enhances hyperpolarization-activated currents in rat aortic baroreceptor neurons: involvement of superoxide.

Journal: American journal of physiology. Cell physiology 20100101

Title: Myoglobin induces vascular cell adhesion molecule-1 expression through c-Src kinase-activator protein-1/nuclear factor-kappaB pathways.

Journal: Nephron. Experimental nephrology 20100101

Title: Aliskiren monotherapy does not cause paradoxical blood pressure rises: meta-analysis of data from 8 clinical trials.

Journal: Hypertension (Dallas, Tex. : 1979) 20100101

Title: Effect of cilnidipine vs losartan on cerebral blood flow in hypertensive patients with a history of ischemic stroke: a randomized controlled trial.

Journal: Acta neurologica Scandinavica 20100101

Title: Angiotensin-(1-7)-angiotensin-converting enzyme 2 attenuates reactive oxygen species formation to angiotensin II within the cell nucleus.

Journal: Hypertension (Dallas, Tex. : 1979) 20100101

Title: Curcumin attenuates glucose-induced monocyte chemoattractant protein-1 synthesis in aortic endothelial cells by modulating the nuclear factor-kappaB pathway.

Journal: Pharmacology 20100101

Title: Choosing an angiotensin-receptor blocker: blood pressure lowering, cardiovascular protection or both?

Journal: Future cardiology 20100101

Title: Medicinal chemistry of drugs used in diabetic cardiomyopathy.

Journal: Current medicinal chemistry 20100101

Title: Role of caveolin and heat shock protein 70 interaction in the antioxidative effects of an angiotensin II type 1 receptor blocker in spontaneously hypertensive rats proximal tubules.

Journal: Journal of hypertension 20100101

Title: Caveolin-1 and Hsp70 interaction in microdissected proximal tubules from spontaneously hypertensive rats as an effect of Losartan.

Journal: Journal of hypertension 20100101

Title: Standards of medical care in diabetes--2010.

Journal: Diabetes care 20100101

Title: Efficacy and tolerability of a fixed-dose combination of metoprolol extended release/amlodipine in patients with mild-to-moderate hypertension: a randomized, parallel-group, multicentre comparison with losartan plus amlodipine.

Journal: Clinical drug investigation 20100101

Title: Losartan therapy in adults with Marfan syndrome: study protocol of the multi-center randomized controlled COMPARE trial.

Journal: Trials 20100101

Title: Use of angiotensin receptor blockers and risk of dementia in a predominantly male population: prospective cohort analysis.

Journal: BMJ (Clinical research ed.) 20100101

Title: A novel method to adjust efficacy estimates for uptake of other active treatments in long-term clinical trials.

Journal: PloS one 20100101

Title: Brain natriuretic peptide is related to diastolic dysfunction whereas urinary albumin excretion rate is related to left ventricular mass in asymptomatic type 2 diabetes patients.

Journal: Cardiovascular diabetology 20100101

Title: Myocardial infarction and stroke associated with diuretic based two drug antihypertensive regimens: population based case-control study.

Journal: BMJ (Clinical research ed.) 20100101

Title: Cost effectiveness of angiotensin receptor blocker monotherapy in patients with hypertension in the Netherlands: a comparative analysis using clinical trial and drug utilization data.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20100101

Title: [Protective effect of losartan on insulin secretion function of RIN-m cells against angiotensin II-induced injury and the mechanism].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20100101

Title: Ramipril mitigates radiation-induced impairment of neurogenesis in the rat dentate gyrus.

Journal: Radiation oncology (London, England) 20100101

Title: [Effect of different doses of losartan on cirrhotic portal hypertensive colopathy in rats].

Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20100101

Title: Losartan normalizes endothelium-derived hyperpolarizing factor-mediated relaxation by activating Ca2+-activated K+ channels in mesenteric artery from type 2 diabetic GK rat.

Journal: Journal of pharmacological sciences 20100101

Title: Management of hyperuricemia in gout: focus on febuxostat.

Journal: Clinical interventions in aging 20100101

Title: Rationale and design of the ADDITION-Leicester study, a systematic screening programme and randomised controlled trial of multi-factorial cardiovascular risk intervention in people with type 2 diabetes mellitus detected by screening.

Journal: Trials 20100101

Title: Allergic reaction related to ramipril use: a case report.

Journal: Diabetology & metabolic syndrome 20100101

Title: Anti-hyperglycemic and anti-hyperlipidemic effects of guava leaf extract.

Journal: Nutrition & metabolism 20100101

Title: Angiotensin II type 2 receptor signaling significantly attenuates growth of murine pancreatic carcinoma grafts in syngeneic mice.

Journal: BMC cancer 20100101

Title: Cyclic stretch enhances the expression of toll-like receptor 4 gene in cultured cardiomyocytes via p38 MAP kinase and NF-kappaB pathway.

Journal: Journal of biomedical science 20100101

Title: Valsartan addition to amlodipine is more effective than losartan addition in hypertensive patients inadequately controlled by amlodipine.

Journal: Vascular health and risk management 20100101

Title: Inflammatory mediators of hepatic steatosis.

Journal: Mediators of inflammation 20100101

Title: Internalization of constitutively active N111G MUTANT of AT1 receptor induced by angiotensin II-receptor antagonists candesartan, losartan, and telmisartan: comparison with valsartan.

Journal: Journal of pharmacological sciences 20100101

Title: Effects of a low-dose antihypertensive diuretic in combination with losartan, telmisartan, or candesartan on serum urate levels in hypertensive patients.

Journal: Arzneimittel-Forschung 20100101

Title: Controlling hypertension immediately post stroke: a cost utility analysis of a pilot randomised controlled trial.

Journal: Cost effectiveness and resource allocation : C/E 20100101

Title: Statins, antihypertensive treatment, and blood pressure control in clinic and over 24 hours: evidence from PHYLLIS randomised double blind trial.

Journal: BMJ (Clinical research ed.) 20100101

Title: [Effect of iron overload on experimental immunological liver injury in rats and the role of angiotensin].

Journal: Wei sheng yan jiu = Journal of hygiene research 20100101

Title: Protective effects of intranasal losartan in the APP/PS1 transgenic mouse model of Alzheimer disease.

Journal: Rejuvenation research 20100101

Title: Effect of losartan on vascular function in fructose-fed rats: the role of perivascular adipose tissue.

Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20100101

Title: Angiotensin II inhibits insulin-stimulated GLUT4 translocation and Akt activation through tyrosine nitration-dependent mechanisms.

Journal: PloS one 20100101

Title: Recent achievements in the management of Raynaud's phenomenon.

Journal: Vascular health and risk management 20100101

Title: Role of valsartan, amlodipine and hydrochlorothiazide fixed combination in blood pressure control: an update.

Journal: Vascular health and risk management 20100101

Title: Role of inflammation in túbulo-interstitial damage associated to obstructive nephropathy.

Journal: Journal of inflammation (London, England) 20100101

Title: [Recent clinical evidences of RAS inhibitors on chronic kidney diseases].

Journal: Nihon Jinzo Gakkai shi 20100101

Title: Autosomal dominant polycystic kidney disease with diffuse proliferative glomerulonephritis - an unusual association: a case report and review of the literature.

Journal: Journal of medical case reports 20100101

Title: Localization of angiotensin converting enzyme in rabbit cornea and its role in controlling corneal angiogenesis in vivo.

Journal: Molecular vision 20100101

Title: Pharmacological evaluation of 'Glyoherb': A polyherbal formulation on streptozotocin-induced diabetic rats.

Journal: International journal of diabetes in developing countries 20100101

Title: The role of renin angiotensin system inhibition in kidney repair.

Journal: Fibrogenesis & tissue repair 20100101

Title: New standards in hypertension and cardiovascular risk management: focus on telmisartan.

Journal: Vascular health and risk management 20100101

Title: Advances in the treatment of Raynaud's phenomenon.

Journal: Vascular health and risk management 20100101

Title: Captopril reduces cardiac inflammatory markers in spontaneously hypertensive rats by inactivation of NF-kB.

Journal: Journal of inflammation (London, England) 20100101

Title: Association of circulating angiotensin converting enzyme activity with respiratory muscle function in infants.

Journal: Respiratory research 20100101

Title: From design to implementation--the Joint Asia Diabetes Evaluation (JADE) program: a descriptive report of an electronic web-based diabetes management program.

Journal: BMC medical informatics and decision making 20100101

Title: On call. I've read your comprehensive discussion of erectile dysfunction, but one aspect is not mentioned: at age 74 (with a new wife, age 70), I can have erections, both with and without Levitra, but I have increasing difficulty achieving difficulty achieving ejaculation. I assume this is related to ED and age, but wonder whether there is a solution. I don't drink or have diabetes. I do have high blood pressure, but it's controlled with Hyzaar and Plendil.

Journal: Harvard men's health watch 20100101

Title: The estimated GFR, but not the stage of diabetic nephropathy graded by the urinary albumin excretion, is associated with the carotid intima-media thickness in patients with type 2 diabetes mellitus: a cross-sectional study.

Journal: Cardiovascular diabetology 20100101

Title: Forecasting drug utilization and expenditure in a metropolitan health region.

Journal: BMC health services research 20100101

Title: Effects of Losartan on expression of connexins at the early stage of atherosclerosis in rabbits.

Journal: International journal of medical sciences 20100101

Title: Severe hepatic encephalopathy in a patient with liver cirrhosis after administration of angiotensin-converting enzyme inhibitor/angiotensin II receptor blocker combination therapy: a case report.

Journal: Journal of medical case reports 20100101

Title: Effect of losartan and benzbromarone on the level of human urate transporter 1 mRNA.

Journal: Arzneimittel-Forschung 20100101

Title: The effect of chronic candesartan therapy on the metabolic profile and renal tissue cytokine levels in the obese Zucker rat.

Journal: Mediators of inflammation 20100101

Title: Angiotensin II upregulates the expression of placental growth factor in human vascular endothelial cells and smooth muscle cells.

Journal: BMC cell biology 20100101

Title: Skeletal dysplasias associated with mild myopathy-a clinical and molecular review.

Journal: Journal of biomedicine & biotechnology 20100101

Title: Rapid cell culture and pre-clinical screening of a transforming growth factor-beta (TGF-beta) inhibitor for orthopaedics.

Journal: BMC musculoskeletal disorders 20100101

Title: Current cardiac imaging techniques for detection of left ventricular mass.

Journal: Cardiovascular ultrasound 20100101

Title: Availability, price and affordability of cardiovascular medicines: a comparison across 36 countries using WHO/HAI data.

Journal: BMC cardiovascular disorders 20100101

Title: Mycophenolic acid area under the curve recovery time following rifampicin withdrawal.

Journal: Indian journal of nephrology 20100101

Title: Ichthyotic-appearing skin changes associated with childhood morphea, systemic sclerosis, and systemic lupus erythematosus/scleroderma overlap.

Journal: Pediatric dermatology 20100101

Title: Optimal use of beta-blockers in high-risk hypertension: a guide to dosing equivalence.

Journal: Vascular health and risk management 20100101

Title: Heart rate control with adrenergic blockade: clinical outcomes in cardiovascular medicine.

Journal: Vascular health and risk management 20100101

Title: Early brief treatment with losartan plus mycophenolate mofetil provides lasting renoprotection in a renal ablation model.

Journal: American journal of nephrology 20100101

Title: Accuracy of advanced versus strictly conventional 12-lead ECG for detection and screening of coronary artery disease, left ventricular hypertrophy and left ventricular systolic dysfunction.

Journal: BMC cardiovascular disorders 20100101

Title: Calcium-sensing receptors regulate cardiomyocyte Ca2+ signaling via the sarcoplasmic reticulum-mitochondrion interface during hypoxia/reoxygenation.

Journal: Journal of biomedical science 20100101

Title: Maitake mushroom extracts ameliorate progressive hypertension and other chronic metabolic perturbations in aging female rats.

Journal: International journal of medical sciences 20100101

Title: Use of evidence-based pharmacotherapy after myocardial infarction in Estonia.

Journal: BMC public health 20100101

Title: Combination therapy in hypertension: An update.

Journal: Diabetology & metabolic syndrome 20100101

Title: RP-HPLC Method for the Determination of Losartan Potassium and Ramipril in Combined Dosage Form.

Journal: Indian journal of pharmaceutical sciences 20100101

Title: Spectrophotometric and HPLC methods for simultaneous estimation of amlodipine besilate, losartan potassium and hydrochlorothiazide in tablets.

Journal: Indian journal of pharmaceutical sciences 20100101

Title: Gene activation regresses atherosclerosis, promotes health, and enhances longevity.

Journal: Lipids in health and disease 20100101

Title: Thyroid Hormone Increases TGF-beta1 in Cardiomyocytes Cultures Independently of Angiotensin II Type 1 and Type 2 Receptors.

Journal: International journal of endocrinology 20100101

Title: Synthesis and Supramolecular Structure of a (5-(3-(1H-tetrazol-5-yl)phenyl)-1H-tetrazole) Cobalt Complex.

Journal: Bioinorganic chemistry and applications 20100101

Title: Despite similar reduction of blood pressure and renal ANG II and ET-1 levels aliskiren but not losartan normalizes albuminuria in hypertensive Ren-2 rats.

Journal: Physiological research 20100101

Title: Factor XII mutations, estrogen-dependent inherited angioedema, and related conditions.

Journal: Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 20100101

Title: Drug-based therapies for vascular disease in Marfan syndrome: from mouse models to human patients.

Journal: The Mount Sinai journal of medicine, New York 20100101

Title: Hemi-central retinal artery occlusion in young adults.

Journal: Indian journal of ophthalmology 20100101

Title: Differences in efficacy and safety of pharmaceutical treatments between men and women: an umbrella review.

Journal: PloS one 20100101

Title: Comparison of laser Doppler imaging, fingertip lacticemy test, and nailfold capillaroscopy for assessment of digital microcirculation in systemic sclerosis.

Journal: Arthritis research & therapy 20100101

Title: A hepatitis C-positive patient with new onset of nephrotic syndrome and systemic amyloidosis secondary to common variable immunodeficiency.

Journal: Annals of Saudi medicine 20100101

Title: Treatment of specific macrovascular beds in patients with diabetes mellitus.

Journal: Osteopathic medicine and primary care 20100101

Title: Nocturnal blood pressure fall as predictor of diabetic nephropathy in hypertensive patients with type 2 diabetes.

Journal: Cardiovascular diabetology 20100101

Title: Advanced glycation end products, oxidative stress and diabetic nephropathy.

Journal: Oxidative medicine and cellular longevity 20100101

Title: Metabolic syndrome, dyslipidemia, hypertension and type 2 diabetes in youth: from diagnosis to treatment.

Journal: Diabetology & metabolic syndrome 20100101

Title: A comparison of the effects of ramipril and losartan on blood pressure control and left ventricle hypertrophy in patients with autosomal dominant polycystic kidney disease.

Journal: Renal failure 20100101

Title: Ang II enhances tubular cell Ets-1 expression and associated down stream signaling is mediated through AT1 receptors.

Journal: Renal failure 20100101

Title: Inhibitory effects of uraemic toxins 3-indoxyl sulfate and p-cresol on losartan metabolism in vitro.

Journal: The Journal of pharmacy and pharmacology 20100101

Title: Do we need more than just powerful blood pressure reductions? New paradigms in end-organ protection.

Journal: Vascular health and risk management 20100101

Title: Blocking the RAAS at different levels: an update on the use of the direct renin inhibitors alone and in combination.

Journal: Vascular health and risk management 20100101

Title: Blood pressure-independent effect of candesartan on cardio-ankle vascular index in hypertensive patients with metabolic syndrome.

Journal: Vascular health and risk management 20100101

Title: Concentration-dependent inhibitory effect of irbesartan on renal uric acid transporters.

Journal: Journal of pharmacological sciences 20100101

Title: Preventive effect of taurine on experimental type II diabetic nephropathy.

Journal: Journal of biomedical science 20100101

Title: Different effects of angiotensin II and angiotensin-(1-7) on vascular smooth muscle cell proliferation and migration.

Journal: PloS one 20100101

Title: Pleural effusions in children undergoing cardiac surgery.

Journal: Annals of pediatric cardiology 20100101

Title: Palmaria palmata (Dulse) as an unusual maritime aetiology of hyperkalemia in a patient with chronic renal failure: a case report.

Journal: Journal of medical case reports 20100101

Title: AT1 receptor induced alterations in histone H2A reveal novel insights into GPCR control of chromatin remodeling.

Journal: PloS one 20100101

Title: Optimal management of sarcopenia.

Journal: Clinical interventions in aging 20100101

Title: Role of olmesartan in combination therapy in blood pressure control and vascular function.

Journal: Vascular health and risk management 20100101

Title: Aliskiren and valsartan combination therapy for the management of hypertension.

Journal: Vascular health and risk management 20100101

Title: Recent advances in the management of chronic stable angina II. Anti-ischemic therapy, options for refractory angina, risk factor reduction, and revascularization.

Journal: Vascular health and risk management 20100101

Title: Triple combination therapy with amlodipine, valsartan, and hydrochlorothiazide vs dual combination therapy with amlodipine and hydrochlorothiazide for stage 2 hypertensive patients.

Journal: Vascular health and risk management 20100101

Title: Electrocardiographic changes with the onset of diabetes and the impact of aerobic exercise training in the Zucker Diabetic Fatty (ZDF) rat.

Journal: Cardiovascular diabetology 20100101

Title: Digital ischemia in scleroderma spectrum of diseases.

Journal: International journal of rheumatology 20100101

Title: Early combined treatment with sildenafil and adipose-derived mesenchymal stem cells preserves heart function in rat dilated cardiomyopathy.

Journal: Journal of translational medicine 20100101

Title: Renal protection in diabetes: lessons from ONTARGET.

Journal: Cardiovascular diabetology 20100101

Title: Inflammation and adipose tissue: effects of progressive load training in rats.

Journal: Lipids in health and disease 20100101

Title: Ventricular septal defect in a child with Alport syndrome: a case report.

Journal: BMC cardiovascular disorders 20100101

Title: Methods for imaging Renin-synthesizing, -storing, and -secreting cells.

Journal: International journal of hypertension 20100101

Title: Cardiovascular Disease, Single Nucleotide Polymorphisms; and the Renin Angiotensin System: Is There a MicroRNA Connection?

Journal: International journal of hypertension 20100101

Title: PPARgamma activation attenuates T-lymphocyte-dependent inflammation of adipose tissue and development of insulin resistance in obese mice.

Journal: Cardiovascular diabetology 20100101

Title: New class of agents for treatment of hypertension: focus on direct renin inhibition.

Journal: Vascular health and risk management 20100101

Title: Urinary proteome analysis enables assessment of renoprotective treatment in type 2 diabetic patients with microalbuminuria.

Journal: BMC nephrology 20100101

Title: Outcome selection and role of patient reported outcomes in contemporary cardiovascular trials: systematic review.

Journal: BMJ (Clinical research ed.) 20100101

Title: Association between different measurements of blood pressure variability by ABP monitoring and ankle-brachial index.

Journal: BMC cardiovascular disorders 20100101

Title: Diabetic cardiomyopathy: from the pathophysiology of the cardiac myocytes to current diagnosis and management strategies.

Journal: Vascular health and risk management 20100101

Title: Population based screening for chronic kidney disease: cost effectiveness study.

Journal: BMJ (Clinical research ed.) 20100101

Title: SNP-SNP interactions dominate the genetic architecture of candidate genes associated with left ventricular mass in African-Americans of the GENOA study.

Journal: BMC medical genetics 20100101

Title: Reference left atrial dimensions and volumes by steady state free precession cardiovascular magnetic resonance.

Journal: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20100101

Title: Methylglyoxal augments angiotensin II-induced contraction in rat isolated carotid artery.

Journal: Journal of pharmacological sciences 20100101

Title: [Effects of combination therapy with losartan/hydrochlorothiazide on the relationships between base blood pressure, autonomic function, and health-related QOL].

Journal: Nihon Jinzo Gakkai shi 20100101

Title: Angiotensin-converting enzyme inhibitors will help in improving stroke outcome if given immediately after stroke.

Journal: Annals of Indian Academy of Neurology 20100101

Title: Effects of atorvastatin and losartan on monocrotaline-induced pulmonary artery remodeling in rats.

Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20100101

Title: [An experience of the use of angiotensin II receptor blocker losartan in patients with metabolic syndrome and chronic kidney disease].

Journal: Kardiologiia 20100101

Title: Effects of aliskiren on stroke in rats expressing human renin and angiotensinogen genes.

Journal: PloS one 20100101

Title: Fibrillin assemblies: extracellular determinants of tissue formation and fibrosis.

Journal: Fibrogenesis & tissue repair 20100101

Title: Single-dose effects of isosorbide mononitrate alone or in combination with losartan on central blood pressure.

Journal: Journal of the American Society of Hypertension : JASH 20100101

Title: Efficacy of combination therapy with telmisartan plus amlodipine in patients with poorly controlled hypertension.

Journal: Oxidative medicine and cellular longevity 20100101

Title: Identification of retinoic acid in a high content screen for agents that overcome the anti-myogenic effect of TGF-beta-1.

Journal: PloS one 20100101

Title: Clinical effectiveness of telmisartan alone or in combination therapy for controlling blood pressure and vascular risk in the elderly.

Journal: Clinical interventions in aging 20100101

Title: Plasmapheresis-induced clinical improvement in a patient with steroid-resistant nephrotic syndrome due to podocin (NPHS2) gene mutation.

Journal: Acta medica (Hradec Kralove) 20100101

Title: Prevention of sodium valproate-induced hepatotoxicity by curcumin, rosiglitazone and N-acetylcysteine in rats.

Journal: Arzneimittel-Forschung 20100101

Title: Food and drug administration's critical path initiative and innovations in drug development paradigm: Challenges, progress, and controversies.

Journal: Journal of pharmacy & bioallied sciences 20100101

Title: Spectrophotometric method for simultaneous estimation of atenolol in combination with losartan potassium and hydrochlorothiazide in bulk and tablet formulation.

Journal: Journal of pharmacy & bioallied sciences 20100101

Title: Cardio classics revisited--focus on the role of candesartan.

Journal: Vascular health and risk management 20100101

Title: Epidemiology of gout.

Journal: Arthritis research & therapy 20100101

Title: Organic nitrates and nitrate resistance in diabetes: the role of vascular dysfunction and oxidative stress with emphasis on antioxidant properties of pentaerithrityl tetranitrate.

Journal: Experimental diabetes research 20100101

Title: Predictors of uncontrolled hypertension and antihypertensive medication nonadherence.

Journal: Journal of cardiovascular disease research 20100101

Title: Dexamethasone pulse therapy in patients of systemic sclerosis: is it a viable proposition? A study from kashmir.

Journal: Indian journal of dermatology 20100101

Title: Achievement of cardiovascular risk factor targets in young adults with diabetes mellitus.

Journal: Diabetes, metabolic syndrome and obesity : targets and therapy 20100101

Title: [Individual renal hemodynamic response to chronic angiotensin II receptor blockade and the influence on the renin-angiotensin system gene polymorphisms].

Journal: Medicinski pregled 20100101

Title: Role of the JAK2/STAT pathway and losartan in human glomerular mesangial cell senescence.

Journal: Molecular medicine reports 20100101

Title: Renovascular and renoprotective properties of telmisartan: clinical utility.

Journal: International journal of nephrology and renovascular disease 20100101

Title: Uncontrolled hypertension secondary to leukemic cell infiltration of kidneys in a hemodialysis patient.

Journal: International journal of nephrology and renovascular disease 20100101

Title: Fifteen years of losartan: what have we learned about losartan that can benefit chronic kidney disease patients?

Journal: International journal of nephrology and renovascular disease 20100101

Title: New and improved strategies for the treatment of gout.

Journal: International journal of nephrology and renovascular disease 20100101

Title: Antihypertensive drugs and erectile dysfunction as seen in spontaneous reports, with focus on angiotensin II type 1 receptor blockers.

Journal: Drug, healthcare and patient safety 20100101

Title: Management of amlodipine-induced gingival enlargement: Series of three cases.

Journal: Journal of Indian Society of Periodontology 20100101

Title: Policies to enhance prescribing efficiency in europe: findings and future implications.

Journal: Frontiers in pharmacology 20100101

Title: Complementary mechanisms of action and rationale for the fixed combination of perindopril and indapamide in treating hypertension - update on clinical utility.

Journal: Integrated blood pressure control 20100101

Title: Endothelial function, blood pressure control, and risk modification: impact of irbesartan alone or in combination.

Journal: Integrated blood pressure control 20100101

Title: Evidence-based approach for managing hypertension in type 2 diabetes.

Journal: Integrated blood pressure control 20100101

Title: Update on the role of candesartan in the optimal management of hypertension and cardiovascular risk reduction.

Journal: Integrated blood pressure control 20100101

Title: Critical appraisal and pooled analysis of telmisartan alone or in combination with hydrochlorothiazide for achieving blood pressure goals.

Journal: Integrated blood pressure control 20100101

Title: Impact of telmisartan in modifying vascular risk.

Journal: Integrated blood pressure control 20100101

Title: Critical appraisal of amlodipine and olmesartan medoxomil fixed-dose combination in achieving blood pressure goals.

Journal: Integrated blood pressure control 20100101

Title: Impact of olmesartan on blood pressure, endothelial function, and cardiovascular outcomes.

Journal: Integrated blood pressure control 20100101

Title: Renoprotection, renin inhibition, and blood pressure control: the impact of aliskiren on integrated blood pressure control.

Journal: Integrated blood pressure control 20100101

Title: Safety and tolerability of fixed antihypertensive combinations in blood pressure control: focus on olmesartan medoxomil and amlodipine combination.

Journal: Integrated blood pressure control 20100101

Title: First-line treatment of hypertension: critical appraisal of potential role of aliskiren and hydrochlorothiazide in a fixed combination.

Journal: Integrated blood pressure control 20100101

Title: A method for content uniformity determination of atenolol and losartan potassium in combined tablet dosage form.

Journal: Indian journal of pharmaceutical sciences 20100101

Title: Wenckebach Block due to Hyperkalemia: A Case Report.

Journal: Emergency medicine international 20100101

Title: Alzheimer's and seizures: interleukin-18, indoleamine 2,3-dioxygenase and quinolinic Acid.

Journal: International journal of tryptophan research : IJTR 20100101

Title: Inflammatory cytokines and atrial fibrillation: current and prospective views.

Journal: Journal of inflammation research 20100101

Title: Trouble shooting during bioanalytical estimation of drug and metabolites using lc-ms/ms: a review.

Journal: Journal of advanced pharmaceutical technology & research 20100101

Title: A novel method for quantitative determination of aceclofenac in bulk drug and tablets using sodium salicylate as a hydrotropic solubilizing agent.

Journal: Journal of advanced pharmaceutical technology & research 20100101

Title: Development of matrix type transdermal patches of lercanidipine hydrochloride: physicochemical and in-vitro characterization.

Journal: Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20100101

Title: Angiotensin III modulates the nociceptive control mediated by the periaqueductal gray matter.

Journal: Neuroscience 20091215

Title: The cardiovascular response of normal rats to dual lesion of the subfornical organ and area postrema at rest and to chronic losartan.

Journal: Brain research 20091211

Title: Endothelial function impairment in chronic venous insufficiency: effect of some cardiovascular protectant agents.

Journal: Angiology 20091201

Title: Effects of apocynin and losartan treatment on renal oxidative stress in a rat model of calcium oxalate nephrolithiasis.

Journal: International urology and nephrology 20091201

Title: Prenatal blockade of Ang II receptors affects neonatal rat hindbrain structure and receptor localization.

Journal: Experimental neurology 20091201

Title: QRS duration predicts sudden cardiac death in hypertensive patients undergoing intensive medical therapy: the LIFE study.

Journal: European heart journal 20091201

Title: Evaluation of the potential for drug-induced liver injury based on in vitro covalent binding to human liver proteins.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20091201

Title: Impact of the PPAR-gamma2 Pro12Ala polymorphism and ACE inhibitor therapy on new-onset microalbuminuria in type 2 diabetes: evidence from BENEDICT.

Journal: Diabetes 20091201

Title: Rosuvastatin attenuates Ang II--mediated cardiomyocyte hypertrophy via inhibition of LOX-1.

Journal: Journal of cardiovascular pharmacology and therapeutics 20091201

Title: Safety and benefits of a tablet combining losartan and hydrochlorothiazide in Japanese diabetic patients with hypertension.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20091201

Title: Angiotensin II and hypertonicity modulate proximal tubular aquaporin 1 expression.

Journal: American journal of physiology. Renal physiology 20091201

Title: Effect of treatment with losartan on salt sensitivity and SGLT2 expression in hypertensive diabetic rats.

Journal: Diabetes research and clinical practice 20091201

Title: Effects of losartan, HO-1 inducers or HO-1 inhibitors on erectile signaling in diabetic rats.

Journal: The journal of sexual medicine 20091201

Title: Angiotensin II regulates the expression of monocyte chemoattractant protein-1 in pancreatic cancer cells.

Journal: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20091201

Title: Direct renin inhibition: an update.

Journal: Current hypertension reports 20091201

Title: Permeation of losartan across human respiratory epithelium: an in vitro study with Calu-3 cells.

Journal: Acta pharmaceutica (Zagreb, Croatia) 20091201

Title: Addition of angiotensin receptor blockade or mineralocorticoid antagonism to maximal angiotensin-converting enzyme inhibition in diabetic nephropathy.

Journal: Journal of the American Society of Nephrology : JASN 20091201

Title: Renin-Angiotensin system suppression mitigates experimental radiation pneumonitis.

Journal: International journal of radiation oncology, biology, physics 20091201

Title: AGTR1 as a therapeutic target in ER-positive and ERBB2-negative breast cancer cases.

Journal: Cell cycle (Georgetown, Tex.) 20091201

Title: Hemodynamic alterations in the coronary circulation of cardiomyopathic hamsters: age and Ang II-dependent mechanisms.

Journal: Journal of cardiac failure 20091201

Title: Symptomatic hypocalcemia in primary hyperaldosteronism: a case report.

Journal: Journal of Korean medical science 20091201

Title: Early administration of enalapril and losartan to patients with type 1 diabetes.

Journal: Current diabetes reports 20091201

Title: Contribution of epidermal growth factor receptor transactivation in angiotensin II-induced enhanced expression of Gi protein and proliferation in A10 vascular smooth muscle cells.

Journal: Canadian journal of physiology and pharmacology 20091201

Title: Biochemical effects of irbesartan in experimental diabetic nephropathy.

Journal: Indian journal of pharmacology 20091201

Title: Divergent effects of losartan and metoprolol on cardiac remodeling, c-kit+ cells, proliferation and apoptosis in the left ventricle after myocardial infarction.

Journal: Clinical and translational science 20091201

Title: Experimental therapies in hypertrophic cardiomyopathy.

Journal: Journal of cardiovascular translational research 20091201

Title: Water and sodium regulation in heart failure.

Journal: Electrolyte & blood pressure : E & BP 20091201

Title: Effects of high-dose versus low-dose losartan on clinical outcomes in patients with heart failure (HEAAL study): a randomised, double-blind trial.

Journal: Lancet (London, England) 20091128

Title: Optimising management of chronic heart failure.

Journal: Lancet (London, England) 20091128

Title: Losartan-antioxidant hybrids: novel molecules for the prevention of hypertension-induced cardiovascular damage.

Journal: Journal of medicinal chemistry 20091126

Title: Multivariate optimization and validation of an analytical methodology by RP-HPLC for the determination of losartan potassium in capsules.

Journal: Talanta 20091115

Title: Influence of endogenous angiotensin II on control of sympathetic nerve activity in human dehydration.

Journal: The Journal of physiology 20091115

Title: Urinary TGF-beta1 as an indicator of antiproteinuric response to angiotensin II receptor blocker in proteinuric renal diseases.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20091101

Title: Clustered metabolic abnormalities blunt regression of hypertensive left ventricular hypertrophy: the LIFE study.

Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD 20091101

Title: Angiotensin II activates connective tissue growth factor and induces extracellular matrix changes involving Smad/activation and p38 mitogen-activated protein kinase signalling pathways in human dermal fibroblasts.

Journal: Experimental dermatology 20091101

Title: Effect of losartan on ambulatory short-term blood pressure variability and cardiovascular remodeling in hypertensive patients on hemodialysis.

Journal: Atherosclerosis 20091101

Title: Angiotensin type 1 receptor mediates thyroid hormone-induced cardiomyocyte hypertrophy through the Akt/GSK-3beta/mTOR signaling pathway.

Journal: Basic research in cardiology 20091101

Title: V1/V2 Vasopressin receptor antagonism potentiates the renoprotection of renin-angiotensin system inhibition in rats with renal mass reduction.

Journal: Kidney international 20091101

Title: Enhanced angiotensin-mediated excitation of renal sympathetic nerve activity within the paraventricular nucleus of anesthetized rats with heart failure.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20091101

Title: Effects of angiotensin II type 1 receptor blocker on ambulatory blood pressure variability in hypertensive patients with overt diabetic nephropathy.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20091101

Title: Regulation of central angiotensin type 1 receptors and sympathetic outflow in heart failure.

Journal: American journal of physiology. Heart and circulatory physiology 20091101

Title: AT1 receptor-mediated uptake of angiotensin II and NHE-3 expression in proximal tubule cells through a microtubule-dependent endocytic pathway.

Journal: American journal of physiology. Renal physiology 20091101

Title: Lack of cardiac fibrosis in a new model of high prorenin hyperaldosteronism.

Journal: American journal of physiology. Heart and circulatory physiology 20091101

Title: Vasopressin is a major vasoconstrictor involved in hindlimb vascular responses to stimulation of adenosine A(1) receptors in the nucleus of the solitary tract.

Journal: American journal of physiology. Heart and circulatory physiology 20091101

Title: Ischemia-induced brain damage is enhanced in human renin and angiotensinogen double-transgenic mice.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20091101

Title: Angiotensin II receptors are expressed and functional in human esophageal mucosa.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20091101

Title: Angiotensin II effects on ischemic focal ventricular tachycardia are predominantly mediated through myocardial AT(2) receptor.

Journal: American journal of physiology. Heart and circulatory physiology 20091101

Title: Long-term effects of losartan on structure and function of the thoracic aorta in a mouse model of Marfan syndrome.

Journal: British journal of pharmacology 20091101

Title: Incidence of heart failure in relation to QRS duration during antihypertensive therapy: the LIFE study.

Journal: Journal of hypertension 20091101

Title: Treatment of prehypertension in diabetes and metabolic syndrome: what are the pros?

Journal: Diabetes care 20091101

Title: Hypertension and diabetes: should we treat early surrogates? What are the cons?

Journal: Diabetes care 20091101

Title: Hypertension and Diabetes: what are the pros to treating early surrogates?

Journal: Diabetes care 20091101

Title: Dual blockade of the renin-angiotensin system in diabetic nephropathy.

Journal: Diabetes care 20091101

Title: Constitutively active mutant N111G of angiotensin II type 1 (AT(1)) receptor induces homologous internalization through mediation of AT(1)-receptor antagonist.

Journal: Journal of pharmacological sciences 20091101

Title: Efficacy and safety of losartan in treatment of hyperuricemia and posttransplantation erythrocytosis: results of a prospective, open, randomized, case-control study.

Journal: Transplantation proceedings 20091101

Title: Effects of angiotensin II receptor blockers on the relationships between ambulatory blood pressure and anti-hypertensive effects, autonomic function, and health-related quality of life.

Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20091101

Title: Outcome of heart failure with preserved ejection fraction: a multicentre spanish registry.

Journal: Current cardiology reviews 20091101

Title: Hypertrophic response to angiotensin II is mediated by protein kinase D-extracellular signal-regulated kinase 5 pathway in human aortic smooth muscle cells.

Journal: Biochemical and biophysical research communications 20091023

Title: Mitral E wave deceleration time to peak E velocity ratio and cardiovascular outcome in hypertensive patients during antihypertensive treatment (from the LIFE echo-substudy).

Journal: The American journal of cardiology 20091015

Title: Treatment of hypertension in children and adolescents.

Journal: Pediatric nephrology (Berlin, Germany) 20091001

Title: Effects of Angelicae tenuissima radix, Angelicae dahuricae radix and Scutellariae radix extracts on cytochrome P450 activities in healthy volunteers.

Journal: Basic & clinical pharmacology & toxicology 20091001

Title: Changes seen in the aging kidney and the effect of blocking the renin-angiotensin system.

Journal: Therapeutic advances in cardiovascular disease 20091001

Title: Angiotensin-(1-7) antagonist, A-779, microinjection into the caudal ventrolateral medulla of renovascular hypertensive rats restores baroreflex bradycardia.

Journal: Peptides 20091001

Title: Brain AT1 angiotensin receptor subtype binding: importance of peptidase inhibition for identification of angiotensin II as its endogenous ligand.

Journal: The Journal of pharmacology and experimental therapeutics 20091001

Title: Renal effects of aliskiren compared with and in combination with irbesartan in patients with type 2 diabetes, hypertension, and albuminuria.

Journal: Diabetes care 20091001

Title: CYP2C9 genotype modifies activity of the renin-angiotensin-aldosterone system in hypertensive men.

Journal: Journal of hypertension 20091001

Title: Effects of the CYP2C9*13 allele on the pharmacokinetics of losartan in healthy male subjects.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20091001

Title: Effects of losartan on hepatic expression of nonphagocytic NADPH oxidase and fibrogenic genes in patients with chronic hepatitis C.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20091001

Title: Central angiotensin AT1 receptors are involved in metabolic adjustments in response to graded exercise in rats.

Journal: Peptides 20091001

Title: Long-term effect of modification of dietary protein intake on the progression of diabetic nephropathy: a randomised controlled trial.

Journal: Diabetologia 20091001

Title: Multivalent ligand-receptor interactions elicit inverse agonist activity of AT(1) receptor blockers against stretch-induced AT(1) receptor activation.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20091001

Title: Phosphate-activated glutaminase-containing neurons in the rat paraventricular nucleus express angiotensin type 1 receptors.

Journal: Hypertension (Dallas, Tex. : 1979) 20091001

Title: Angiotensin II induces connective tissue growth factor and collagen I expression via transforming growth factor-beta-dependent and -independent Smad pathways: the role of Smad3.

Journal: Hypertension (Dallas, Tex. : 1979) 20091001

Title: Losartan metabolite EXP3179: an AT1-receptor-independent treatment strategy for patients with the metabolic syndrome?

Journal: Hypertension (Dallas, Tex. : 1979) 20091001

Title: Protein kinase C-inhibiting properties of the losartan metabolite EXP3179 make the difference.

Journal: Hypertension (Dallas, Tex. : 1979) 20091001

Title: Chronic treatment with losartan results in sufficient serum levels of the metabolite EXP3179 for PPARgamma activation.

Journal: Hypertension (Dallas, Tex. : 1979) 20091001

Title: Losartan metabolite EXP3179 blocks NADPH oxidase-mediated superoxide production by inhibiting protein kinase C: potential clinical implications in hypertension.

Journal: Hypertension (Dallas, Tex. : 1979) 20091001

Title: Lowering arterial pressure delays the oxidative stress generation in a renal experimental model of hypertension.

Journal: Journal of cardiovascular pharmacology 20091001

Title: Production and secretion of adiponectin from 3T3-L1 adipocytes: comparison of antihypertensive drugs.

Journal: American journal of hypertension 20091001

Title: Interaction between renin-angiotensin and sympathetic nervous systems in a rat model of pressure overload cardiac hypertrophy.

Journal: Autonomic & autacoid pharmacology 20091001

Title: Rapid determination of losartan and losartan acid in human plasma by multiplexed LC-MS/MS.

Journal: Journal of separation science 20091001

Title: Clinical experience in treating hypertension with fixed-dose combination therapy: angiotensin II receptor blocker losartan plus hydrochlorothiazide.

Journal: Expert opinion on drug metabolism & toxicology 20091001

Title: Cost-effectiveness of aliskiren in type 2 diabetes, hypertension, and albuminuria.

Journal: Journal of the American Society of Nephrology : JASN 20091001

Title: A randomized, double-blind, placebo-controlled study to determine the effects of valsartan on exercise time in patients with symptomatic heart failure with preserved ejection fraction.

Journal: European journal of heart failure 20091001

Title: Renal and retinal effects of enalapril and losartan in type 1 diabetes.

Journal: The New England journal of medicine 20091001

Title: Renal and retinal effects of enalapril and losartan in type 1 diabetes.

Journal: The New England journal of medicine 20091001

Title: Safety and feasibility of achieving lower systolic blood pressure goals in persons with type 2 diabetes: the SANDS trial.

Journal: Journal of clinical hypertension (Greenwich, Conn.) 20091001

Title: Chronic treatment with losartan (angiotensin II type 1 receptor antagonist) normalizes enhanced acetylcholine-induced coronary vasoconstriction in isolated perfused hearts of type 2 diabetic OLETF rats.

Journal: Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20091001

Title: Loeys-Dietz syndrome: a Marfan-like syndrome associated with aggressive vasculopathy.

Journal: Singapore medical journal 20091001

Title: [Effects of losartan and simvastatin on collagen content, myocardial expression of MMP-2 mRNA, MMP-9 mRNA and TIMP-1 mRNA, TIMP-2 mRNA in pressure overload rat hearts].

Journal: Zhonghua xin xue guan bing za zhi 20091001

Title: Angiotensin converting enzyme gene polymorphism in type II diabetics with nephropathy.

Journal: Indian journal of nephrology 20091001

Title: Neointimal-specific induction of apoptosis by losartan results in regression of vascular lesion in rat aorta.

Journal: European journal of pharmacology 20090915

Title: High ambient glucose induces angiotensin-independent AT-1 receptor activation, leading to increases in proliferation and extracellular matrix accumulation in MES-13 mesangial cells.

Journal: The Biochemical journal 20090914

Title: Determination of losartan, telmisartan, and valsartan by direct injection of human urine into a column-switching liquid chromatographic system with fluorescence detection.

Journal: Journal of pharmaceutical and biomedical analysis 20090908

Title: Losartan reduces liver expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced rat nonalcoholic fatty liver disease model.

Journal: Atherosclerosis 20090901

Title: Prevention of aortic elastic lamina defects by losartan in apolipoprotein(E)-deficient mouse.

Journal: Clinical and experimental pharmacology & physiology 20090901

Title: Long-term regulation of vacuolar H(+)-ATPase by angiotensin II in proximal tubule cells.

Journal: Pflugers Archiv : European journal of physiology 20090901

Title: Losartan and tempol treatments normalize the increased response to hydrogen peroxide in resistance arteries from hypertensive rats.

Journal: Journal of hypertension 20090901

Title: In vitro and in vivo studies on chitosan beads of losartan Duolite AP143 complex, optimized by using statistical experimental design.

Journal: AAPS PharmSciTech 20090901

Title: Angiotensin II up-regulates PAX2 oncogene expression and activity in prostate cancer via the angiotensin II type I receptor.

Journal: The Prostate 20090901

Title: The uterine placental bed Renin-Angiotensin system in normal and preeclamptic pregnancy.

Journal: Endocrinology 20090901

Title: Diabetes mellitus and expression of the enterocyte renin-angiotensin system: implications for control of glucose transport across the brush border membrane.

Journal: American journal of physiology. Cell physiology 20090901

Title: Long-term therapeutic effect of vitamin D analog doxercalciferol on diabetic nephropathy: strong synergism with AT1 receptor antagonist.

Journal: American journal of physiology. Renal physiology 20090901

Title: Immunosuppressive effect of angiotensin receptor blocker on stimulation of mice CTLs by angiotensin II.

Journal: International immunopharmacology 20090901

Title: Substrate-dependent functional alterations of seven CYP2C9 variants found in Japanese subjects.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20090901

Title: Regulation of glucose uptake in mesangial cells stimulated by high glucose: role of angiotensin II and insulin.

Journal: Experimental biology and medicine (Maywood, N.J.) 20090901

Title: Sympathetic-mediated hypertension of awake juvenile rats submitted to chronic intermittent hypoxia is not linked to baroreflex dysfunction.

Journal: Experimental physiology 20090901

Title: Is there a role for direct renin inhibitors in chronic kidney disease?

Journal: Current opinion in nephrology and hypertension 20090901

Title: Endogenous angiotensin II facilitates GABAergic neurotransmission afferent to the Na+-responsive neurons of the rat median preoptic nucleus.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20090901

Title: Mouse GLUT9: evidences for a urate uniporter.

Journal: American journal of physiology. Renal physiology 20090901

Title: Chronic central versus systemic blockade of AT(1) receptors and cardiac dysfunction in rats post-myocardial infarction.

Journal: American journal of physiology. Heart and circulatory physiology 20090901

Title: Losartan reduces the onset of type 2 diabetes in hypertensive Japanese patients with chronic hepatitis C.

Journal: Journal of medical virology 20090901

Title: Chlorthalidone - a renaissance in use?

Journal: Expert opinion on pharmacotherapy 20090901

Title: AT(1) receptor blockers increase insulin-like growth factor-I production by stimulating sensory neurons in spontaneously hypertensive rats.

Journal: Translational research : the journal of laboratory and clinical medicine 20090901

Title: Renal dysfunction potentiates foam cell formation by repressing ABCA1.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20090901

Title: CYP2C9 genotype and pharmacodynamic responses to losartan in patients with primary and secondary kidney diseases.

Journal: European journal of clinical pharmacology 20090901

Title: Acquisition of the contractile phenotype by murine arterial smooth muscle cells depends on the Mir143/145 gene cluster.

Journal: The Journal of clinical investigation 20090901

Title: Antiproteinuric and blood pressure-lowering effects of a fixed-dose combination of losartan and hydrochlorothiazide in hypertensive patients with stage 3 chronic kidney disease.

Journal: Pharmacotherapy 20090901

Title: Fluorofenidone attenuates collagen I and transforming growth factor-beta1 expression through a nicotinamide adenine dinucleotide phosphate oxidase-dependent way in NRK-52E cells.

Journal: Nephrology (Carlton, Vic.) 20090901

Title: Long-term effects of rosiglitazone on the progressive decline in renal function in patients with type 2 diabetes.

Journal: The Korean journal of internal medicine 20090901

Title: Effect of angiotensin II type-1 receptor blockers on stable allograft kidneys: prospective randomized study.

Journal: Transplantation proceedings 20090901

Title: Additive antihypertensive and antihypertrophic effects of long-acting Ca blockers in uncontrolled hypertensive patients with angiotensin-receptor blocker based treatment.

Journal: International heart journal 20090901

Title: Genetic polymorphism of the human cytochrome P450 2C9 gene and its clinical significance.

Journal: Current drug metabolism 20090901

Title: Clinical trials of the past decade in the management of chronic kidney disease.

Journal: Reviews on recent clinical trials 20090901

Title: Correction of endothelial dysfunction with impaza preparation in complex with enalapril and losartan during modeling of NO deficiency.

Journal: Bulletin of experimental biology and medicine 20090901

Title: Effect of impaza on cardiovascular system.

Journal: Bulletin of experimental biology and medicine 20090901

Title: Experimental study of hypotensive effect of kardos in rats with inherited hypertension.

Journal: Bulletin of experimental biology and medicine 20090901

Title: Circulating transforming growth factor-beta in Marfan syndrome.

Journal: Circulation 20090811

Title: Losartan exerts renoprotection through NAD(P)H oxidase downregulation in a renovascular model of hypertension.

Journal: Regulatory peptides 20090807

Title: Effects of high sodium intake and diuretics on the circadian rhythm of blood pressure in type 2 diabetic patients treated with an angiotensin II receptor blocker.

Journal: Clinical and experimental nephrology 20090801

Title: Crosstalk between peroxisome proliferator-activated receptor-gamma and angiotensin II in renal tubular epithelial cells in IgA nephropathy.

Journal: Clinical immunology (Orlando, Fla.) 20090801

Title: Primary aldosteronism: diagnostic accuracy of the losartan and captopril tests.

Journal: American journal of hypertension 20090801

Title: PPARgamma agonist, rosiglitazone, regulates angiotensin II-induced vascular inflammation through the TLR4-dependent signaling pathway.

Journal: Laboratory investigation; a journal of technical methods and pathology 20090801

Title: Catheter ablation vs. amiodarone plus losartan for prevention of atrial fibrillation recurrence in patients with paroxysmal atrial fibrillation.

Journal: European journal of clinical investigation 20090801

Title: Genetic variant of the Renin-Angiotensin system and diabetes influences blood pressure response to Angiotensin receptor blockers.

Journal: Diabetes care 20090801

Title: Antagonist of the type-1 ANG II receptor prevents against LPS-induced septic shock in rats.

Journal: Intensive care medicine 20090801

Title: Dual ACE-inhibition and AT1 receptor antagonism improves ventricular lusitropy without affecting cardiac fibrosis in the congenic mRen2.Lewis rat.

Journal: Therapeutic advances in cardiovascular disease 20090801

Title: Effects of salt supplementation on the albuminuric response to telmisartan with or without hydrochlorothiazide therapy in hypertensive patients with type 2 diabetes are modulated by habitual dietary salt intake.

Journal: Diabetes care 20090801

Title: Synergistic inhibitory effect of gemcitabine and angiotensin type-1 receptor blocker, losartan, on murine pancreatic tumor growth via anti-angiogenic activities.

Journal: Oncology reports 20090801

Title: Effect of adrenotensin on cell proliferation is mediated by angiotensin II in cultured rat mesangial cells.

Journal: Acta pharmacologica Sinica 20090801

Title: The value of irbesartan in the management of hypertension.

Journal: Expert opinion on pharmacotherapy 20090801

Title: Renoprotect and blood pressure lowering effect of low-dose hydrochlorothiazide added to intensive renin-angiotensin inhibition in hypertensive patients with chronic kidney disease.

Journal: International journal of clinical pharmacology and therapeutics 20090801

Title: Effects of angiotensin receptor blocker on oxidative stress and cardio-renal function in streptozotocin-induced diabetic rats.

Journal: Biological & pharmaceutical bulletin 20090801

Title: Left ventricular hypertrophy may be transient in the emergency department.

Journal: The western journal of emergency medicine 20090801

Title: Effects of losartan on catecholamine release in the isolated rat adrenal gland.

Journal: The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20090801

Title: Effect of enalapril and losartan on proteinuria in type 2 diabetic nephropathy patients.

Journal: Bangladesh Medical Research Council bulletin 20090801

Title: Diminished renal function and the incidence of heart failure.

Journal: Current cardiology reviews 20090801

Title: Binding sites of valsartan, candesartan and losartan with angiotensin II receptor 1 subtype by molecular modeling.

Journal: Life sciences 20090717

Title: Menopause and ovariectomy cause a low grade of systemic inflammation that may be prevented by chronic treatment with low doses of estrogen or losartan.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20090715

Title: Renal and retinal effects of enalapril and losartan in type 1 diabetes.

Journal: The New England journal of medicine 20090702

Title: The angiotensin-calcineurin-NFAT pathway mediates stretch-induced up-regulation of matrix metalloproteinases-2/-9 in atrial myocytes.

Journal: Basic research in cardiology 20090701

Title: Consequences of perinatal treatment with L-arginine and antioxidants for the renal transcriptome in spontaneously hypertensive rats.

Journal: Pflugers Archiv : European journal of physiology 20090701

Title: Effects of combination therapy with perindopril and losartan on left ventricular remodelling in patients with myocardial infarction.

Journal: Clinical and experimental pharmacology & physiology 20090701

Title: Fabry disease: progression of nephropathy, and prevalence of cardiac and cerebrovascular events before enzyme replacement therapy.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090701

Title: The L-4F mimetic peptide prevents insulin resistance through increased levels of HO-1, pAMPK, and pAKT in obese mice.

Journal: Journal of lipid research 20090701

Title: Prevalence of microalbuminuria and associated electrocardiographic abnormalities in an Indo-Asian population.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090701

Title: Endogenous angiotensin II has fewer effects but neuronal nitric oxide synthase has excitatory effects on renal sympathetic nerve activity in salt-sensitive hypertension-induced heart failure.

Journal: The journal of physiological sciences : JPS 20090701

Title: Enhanced cardiac sympathetic afferent reflex involved in sympathetic overactivity in renovascular hypertensive rats.

Journal: Experimental physiology 20090701

Title: AT(1) receptor activation regulates the mRNA expression of CAT1, CAT2, arginase-1, and DDAH2 in preglomerular vessels from angiotensin II hypertensive rats.

Journal: American journal of physiology. Renal physiology 20090701

Title: (Pro)renin receptor-mediated signal transduction and tissue renin-angiotensin system contribute to diabetes-induced retinal inflammation.

Journal: Diabetes 20090701

Title: Effect of early versus late AT(1) receptor blockade with losartan on postmyocardial infarction ventricular remodeling in rabbits.

Journal: American journal of physiology. Heart and circulatory physiology 20090701

Title: Angiotensin II receptor blockers in pregnancy: a report of five cases.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20090701

Title: A randomized, comparative study evaluating the efficacy and tolerability of losartan-low dose chlorthalidone (6.25 mg) combination with losartan-hydrochlorothiazide (12.5 mg) combination in Indian patients with mild-to-moderate essential hypertension.

Journal: Expert opinion on pharmacotherapy 20090701

Title: Proniosomal transdermal therapeutic system of losartan potassium: development and pharmacokinetic evaluation.

Journal: Journal of drug targeting 20090701

Title: Hydrophilic interaction chromatography-tandem mass spectrometric analysis of irbesartan in human plasma: application to pharmacokinetic study of irbesartan.

Journal: Journal of separation science 20090701

Title: (Pro)renin receptor: a treatment target for diabetic retinopathy?

Journal: Diabetes 20090701

Title: Anemia, diabetes, and chronic kidney disease.

Journal: Diabetes care 20090701

Title: Endogenous angiotensin II modulates nNOS expression in renovascular hypertension.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20090701

Title: [Combination therapy of ARB with diuretics in Japanese hypertensive patients].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20090701

Title: Health-related quality of life and blood pressure control in hypertensive patients with and without complications.

Journal: Clinics (Sao Paulo, Brazil) 20090701

Title: Comparative evaluation of the antihypertensive activities of losartan and HM70186 during liver dysfunction.

Journal: Archives of pharmacal research 20090701

Title: Comparative antihypertensive activities of losartan and HM70186 in rats with hepatic dysfunction.

Journal: Archives of pharmacal research 20090701

Title: [NADPH oxidase-derived reactive oxygen species involved in angiotensin II-induced monocyte chemoattractant protein-1 expression in mesangial cells].

Journal: Zhonghua bing li xue za zhi = Chinese journal of pathology 20090701

Title: Simultaneous determination of losartan and hydrochlorothiazide in human plasma by LC/MS/MS with electrospray ionization and its application to pharmacokinetics.

Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20090701

Title: Coronary artery disease, left ventricular hypertrophy and diastolic dysfunction are associated with stroke in patients affected by persistent non-valvular atrial fibrillation: a case-control study.

Journal: Heart international 20090630

Title: The angiotensin II-AT1 receptor stimulates reactive oxygen species within the cell nucleus.

Journal: Biochemical and biophysical research communications 20090626

Title: Losartan/Hydrochlorothiazide: a review of its use in the treatment of hypertension and for stroke risk reduction in patients with hypertension and left ventricular hypertrophy.

Journal: Drugs 20090618

Title: [Hypertension and the heart].

Journal: Ugeskrift for laeger 20090615

Title: Chronic treatment with losartan and carvedilol differentially modulates renal vascular responses to sympathomimetics compared to treatment with individual agents in normal Wistar Kyoto and spontaneously hypertensive rats.

Journal: European journal of pharmacology 20090610

Title: Prolonged exposure of cardiac cells to renin plus angiotensinogen reduces intracellular renin in the failing heart. On the role of angiotensin II-AT1 complex internalization.

Journal: Regulatory peptides 20090605

Title: Renal medullary effects of transient prehypertensive treatment in young spontaneously hypertensive rats.

Journal: Acta physiologica (Oxford, England) 20090601

Title: Induction of apoptosis in leukemic cell lines treated with captopril, trandolapril and losartan: a new role in the treatment of leukaemia for these agents.

Journal: Leukemia research 20090601

Title: Angiotensin-(1-7) activates a tyrosine phosphatase and inhibits glucose-induced signalling in proximal tubular cells.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090601

Title: Adiponectin is positively associated with insulin resistance in subjects with type 2 diabetic nephropathy and effects of angiotensin II type 1 receptor blocker losartan.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090601

Title: Cardiovascular and autonomic phenotype of db/db diabetic mice.

Journal: Experimental physiology 20090601

Title: Effect of silymarin on the pharmacokinetics of losartan and its active metabolite E-3174 in healthy Chinese volunteers.

Journal: European journal of clinical pharmacology 20090601

Title: Beneficial effect of triple treatment plus immunoglobulin in experimental nephrotic syndrome.

Journal: Pediatric nephrology (Berlin, Germany) 20090601

Title: Nuclear angiotensin II type 2 (AT2) receptors are functionally linked to nitric oxide production.

Journal: American journal of physiology. Renal physiology 20090601

Title: Brain nuclear factor-kappa B activation contributes to neurohumoral excitation in angiotensin II-induced hypertension.

Journal: Cardiovascular research 20090601

Title: HPLC determination of irbesartan in human plasma: its application to pharmacokinetic studies.

Journal: Biomedical chromatography : BMC 20090601

Title: Diabetic retinal neurodegeneration is associated with mitochondrial oxidative stress and is improved by an angiotensin receptor blocker in a model combining hypertension and diabetes.

Journal: Diabetes 20090601

Title: Impact of diabetes on treatment-induced changes in left ventricular structure and function in hypertensive patients with left ventricular hypertrophy. The LIFE study.

Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD 20090601

Title: Time courses of subcellular signal transduction and cellular apoptosis in remote viable myocardium of rat left ventricles following acute myocardial infarction: role of pharmacomodulation.

Journal: Journal of cardiovascular pharmacology and therapeutics 20090601

Title: Antihypertensive effects of central ablations in spontaneously hypertensive rats.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20090601

Title: Involvement of central angiotensin II type 1 receptors in LPS-induced systemic vasopressin release and blood pressure regulation in rats.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20090601

Title: Losartan preserves erectile function after bilateral cavernous nerve injury via antifibrotic mechanisms in male rats.

Journal: The Journal of urology 20090601

Title: Effectiveness of open-label losartan/hydrochlorothiazide combination therapy in Asian patients with hypertension not controlled with ACE inhibitor or ARB monotherapy.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20090601

Title: Effect of soy extract administration on losartan pharmacokinetics in healthy female volunteers.

Journal: The Annals of pharmacotherapy 20090601

Title: Effects of structured versus usual care on renal endpoint in type 2 diabetes: the SURE study: a randomized multicenter translational study.

Journal: Diabetes care 20090601

Title: Intensive diabetes management for high-risk patients: how best to deliver?

Journal: Diabetes care 20090601

Title: The effect of enalapril on skin flap viability is independent of angiotensin II AT1 receptors.

Journal: Annals of plastic surgery 20090601

Title: Gout--what are the treatment options?

Journal: Expert opinion on pharmacotherapy 20090601

Title: Late renal medullary effects of transient angiotensin II receptor blockade in immature spontaneously hypertensive rats.

Journal: Acta physiologica (Oxford, England) 20090601

Title: Beneficial effects of high-dose losartan in IgA nephritis.

Journal: Clinical nephrology 20090601

Title: [Losartan inhibits high glucose-induced CTGF expression via ERK1/2 MAPK pathways in mouse mesangial cells].

Journal: Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20090601

Title: Established and newly proposed mechanisms of chronic cyclosporine nephropathy.

Journal: The Korean journal of internal medicine 20090601

Title: Synergistic decrease in blood pressure by captopril combined with losartan in spontaneous hypertensive rats.

Journal: Archives of pharmacal research 20090601

Title: Postural changes in blood pressure associated with interactions between candidate genes for chronic respiratory diseases and exposure to particulate matter.

Journal: Environmental health perspectives 20090601

Title: IL-8/CXCL8 Upregulates 12-Lipoxygenase Expression in Vascular Smooth Muscle Cells from Spontaneously Hypertensive Rats.

Journal: Immune network 20090601

Title: Mechanisms of potentiation of Angiotensin II-induced contractile response of isolated rat aorta by hydrogen peroxide and tert-butyryl hydroperoxide.

Journal: Indian journal of pharmacology 20090601

Title: Rapid Hemodynamic Deterioration and Death due to Acute Severe Refractory Septic Shock.

Journal: Journal of clinical medicine research 20090601

Title: Cuff-induced vascular intima thickening is influenced by titration of the Ace gene in mice.

Journal: Physiological genomics 20090513

Title: Angiotensin II inhibits GABAergic synaptic transmission in dorsolateral periaqueductal gray neurons.

Journal: Neuroscience letters 20090508

Title: Dihydrotestosterone stimulates aldosterone secretion by H295R human adrenocortical cells.

Journal: Molecular and cellular endocrinology 20090506

Title: Losartan prevents sepsis-induced acute lung injury and decreases activation of nuclear factor kappaB and mitogen-activated protein kinases.

Journal: Shock (Augusta, Ga.) 20090501

Title: Angiotensin II receptor 1 involved in the central pressor response induced by interleukin-1 beta in the paraventricular nucleus.

Journal: Neurological research 20090501

Title: Extracellular matrix metalloproteinase inducer (EMMPRIN) is present in smooth muscle cells of human aneurysmal aorta and is induced by angiotensin II in vitro.

Journal: Clinical science (London, England : 1979) 20090501

Title: Losartan inhibits monocytic adhesion induced by ADMA via downregulation of chemokine receptors in monocytes.

Journal: European journal of clinical pharmacology 20090501

Title: Inhibition of angiotensin type 1 receptor impairs renal ability of K conservation in response to K restriction.

Journal: American journal of physiology. Renal physiology 20090501

Title: Unexpected effect of angiotensin AT1 receptor blockade on tubuloglomerular feedback in early subtotal nephrectomy.

Journal: American journal of physiology. Renal physiology 20090501

Title: Involvement of redox-sensitive extracellular-regulated kinases in angiotensin II-induced interleukin-6 expression in pancreatic acinar cells.

Journal: The Journal of pharmacology and experimental therapeutics 20090501

Title: Angiotensin II upregulates hypothalamic AT1 receptor expression in rats via the mitogen-activated protein kinase pathway.

Journal: American journal of physiology. Heart and circulatory physiology 20090501

Title: Defects in cutaneous angiotensin-converting enzyme 2 and angiotensin-(1-7) production in postural tachycardia syndrome.

Journal: Hypertension (Dallas, Tex. : 1979) 20090501

Title: Transcriptome of hypertension-induced left ventricular hypertrophy and its regression by antihypertensive therapies.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20090501

Title: Diabetic cardiomyopathy.

Journal: Clinical science (London, England : 1979) 20090501

Title: Erectile dysfunction and heart failure: the role of phosphodiesterase type 5 inhibitors.

Journal: International journal of impotence research 20090501

Title: Effects of angiotensin II receptor blockers on relationships between 24-hour blood pressure, autonomic function, and health-related QOL.

Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20090501

Title: Valsartan vs. other angiotensin II receptor blockers in the treatment of hypertension: a meta-analytical approach.

Journal: International journal of clinical practice 20090501

Title: Antiproteinuric therapy decreases LDL-cholesterol as well as HDL-cholesterol in non-diabetic proteinuric patients: relationships with cholesteryl ester transfer protein mass and adiponectin.

Journal: Expert opinion on therapeutic targets 20090501

Title: Reduction of microalbuminuria by using losartan in normotensive patients with type 2 diabetes mellitus: A randomized controlled trial.

Journal: Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20090501

Title: Astragalus mongholicus ameliorates renal fibrosis by modulating HGF and TGF-beta in rats with unilateral ureteral obstruction.

Journal: Journal of Zhejiang University. Science. B 20090501

Title: Managing toxicities and optimal dosing of targeted drugs in advanced kidney cancer.

Journal: Current oncology (Toronto, Ont.) 20090501

Title: CORD: COmparsion of Recommended Doses of ACE inhibitors and angiotensin II receptor blockers.

Journal: Vnitrni lekarstvi 20090501

Title: Changes in the composition of the thoracic aortic wall in spontaneously hypertensive rats treated with losartan or spironolactone.

Journal: Clinical and experimental pharmacology & physiology 20090501

Title: [Economic impact of Losartan use in type 2 diabetic patients with nephropathy].

Journal: Revista medica de Chile 20090501

Title: The effect of telmisartan on endothelial function and arterial stiffness in patients with essential hypertension.

Journal: Korean circulation journal 20090501

Title: Prognostic value of changes in the electrocardiographic strain pattern during antihypertensive treatment: the Losartan Intervention for End-Point Reduction in Hypertension Study (LIFE).

Journal: Circulation 20090414

Title: Simultaneous quantification of losartan and active metabolite in human plasma by liquid chromatography-tandem mass spectrometry using irbesartan as internal standard.

Journal: Journal of pharmaceutical and biomedical analysis 20090405

Title: Losartan decreased premature ventricular contractions in patients with hypertension.

Journal: Journal of human hypertension 20090401

Title: Efficacy of exercise, losartan, enalapril, atenolol and rilmenidine in subjects with blood pressure hyperreactivity at treadmill stress test and left ventricular hypertrophy.

Journal: Journal of human hypertension 20090401

Title: Reduced progression of adriamycin nephropathy in spontaneously hypertensive rats treated by losartan.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090401

Title: Prediction of the effects of genetic polymorphism on the pharmacokinetics of CYP2C9 substrates from in vitro data.

Journal: Pharmaceutical research 20090401

Title: Nail-patella syndrome, infantile nephrotic syndrome: complete remission with antiproteinuric treatment.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090401

Title: Regulation of nerve growth factor in the heart: the role of the calcineurin-NFAT pathway.

Journal: Journal of molecular and cellular cardiology 20090401

Title: Battle against the renin-angiotensin system: help from an unexpected party.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090401

Title: Chronic NHE-1 blockade induces an antiapoptotic effect in the hypertrophied heart.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20090401

Title: Antihypertensive therapy, new-onset diabetes, and cardiovascular disease.

Journal: International journal of clinical practice 20090401

Title: Cerebral vasomotor reactivity before and after blood pressure reduction in hypertensive patients.

Journal: American journal of hypertension 20090401

Title: Type-1 angiotensin receptors are expressed and transported in motor and sensory axons of rat sciatic nerves.

Journal: Neuropeptides 20090401

Title: Short-term oral treatment with the angiotensin II receptor antagonist losartan does not improve coronary vasomotor function in asymptomatic type 2 diabetes patients.

Journal: Diabetes research and clinical practice 20090401

Title: Efficacy and safety of losartan 100 mg or losartan 100 mg plus hydrochlorothiazide 25 mg in the treatment of patients with essential arterial hypertension and CV risk factors: observational, prospective study in primary care.

Journal: Current medical research and opinion 20090401

Title: Glomerular type 1 angiotensin receptors augment kidney injury and inflammation in murine autoimmune nephritis.

Journal: The Journal of clinical investigation 20090401

Title: Synergism of simvastatin with losartan prevents angiotensin II-induced cardiomyocyte apoptosis in vitro.

Journal: The Journal of pharmacy and pharmacology 20090401

Title: A high-throughput assay using liquid chromatography-tandem mass spectrometry for simultaneous in vivo phenotyping of 5 major cytochrome p450 enzymes in patients.

Journal: Therapeutic drug monitoring 20090401

Title: Protective effects of angiotensin AT1 receptor blockade in malignant hypertension in the rat.

Journal: European journal of pharmacology 20090401

Title: [The contribution of ARB to medical treatment].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20090401

Title: [Pharmacological characteristics of ARB and potential strategy to develop novel ARB].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20090401

Title: Irbesartan and hydrochlorothiazide association in the treatment of hypertension.

Journal: Current vascular pharmacology 20090401

Title: Exercise and cardiovascular outcomes in hypertensive patients in relation to structure and function of left ventricular hypertrophy: the LIFE study.

Journal: European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 20090401

Title: Ginsenoside Rb1, a panoxadiol saponin against oxidative damage and renal interstitial fibrosis in rats with unilateral ureteral obstruction.

Journal: Chinese journal of integrative medicine 20090401

Title: [Effect of cordyceps sinensis extract on Klotho expression and apoptosis in renal tubular epithelial cells induced by angiotensin II].

Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20090401

Title: Rationale and design of a trial evaluating the effects of losartan vs. nebivolol vs. the association of both on the progression of aortic root dilation in Marfan syndrome with FBN1 gene mutations.

Journal: Journal of cardiovascular medicine (Hagerstown, Md.) 20090401

Title: Endothelial and non-endothelial coronary blood flow reserve and left ventricular dysfunction in systemic hypertension.

Journal: Clinics (Sao Paulo, Brazil) 20090401

Title: Association between inappropriateness of left ventricular mass and left ventricular diastolic dysfunction: a study using the tissue Doppler parameter, e/e'.

Journal: Korean circulation journal 20090401

Title: Losartan/Hydrochlorothiazide fixed combination versus amlodipine monotherapy in korean patients with mild to moderate hypertension.

Journal: Korean circulation journal 20090401

Title: Effect of lowering blood pressure on cardiovascular events and mortality in patients on dialysis: a systematic review and meta-analysis of randomised controlled trials.

Journal: Lancet (London, England) 20090321

Title: Development of a CP 31P NMR broadline simulation methodology for studying the interactions of antihypertensive AT1 antagonist losartan with phospholipid bilayers.

Journal: Biophysical journal 20090318

Title: Angiotensin II signaling increases activity of the renal Na-Cl cotransporter through a WNK4-SPAK-dependent pathway.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20090317

Title: Angiotensin II increases collagen I expression via transforming growth factor-beta1 and extracellular signal-regulated kinase in cardiac fibroblasts.

Journal: European journal of pharmacology 20090315

Title: [Aliskiren combined with losartan in type 2-diabetes and nephropathy - secondary publication].

Journal: Ugeskrift for laeger 20090309

Title: Effects of bradykinin on venous capacitance in health and treated chronic heart failure.

Journal: Clinical science (London, England : 1979) 20090301

Title: Involvement of prolylcarboxypeptidase in the effect of rutaecarpine on the regression of mesenteric artery hypertrophy in renovascular hypertensive rats.

Journal: Clinical and experimental pharmacology & physiology 20090301

Title: Angiotensin II reduces mitochondrial content in skeletal muscle and affects glycemic control.

Journal: Diabetes 20090301

Title: Mechanisms in the PVN mediating local and central sodium-induced hypertension in Wistar rats.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20090301

Title: Increased vascular angiotensin type 2 receptor expression and NOS-mediated mechanisms of vascular relaxation in pregnant rats.

Journal: American journal of physiology. Heart and circulatory physiology 20090301

Title: Losartan, an Angiotensin type I receptor, restores erectile function by downregulation of cavernous renin-angiotensin system in streptozocin-induced diabetic rats.

Journal: The journal of sexual medicine 20090301

Title: Influence of sympathetic and AT-receptor blockade on angiotensin II and adrenergic agonist-induced renal vasoconstrictions in spontaneously hypertensive rats.

Journal: Acta physiologica (Oxford, England) 20090301

Title: Effects of losartan compared with atenolol on lipids in patients with hypertension and left ventricular hypertrophy: the Losartan Intervention For Endpoint reduction in hypertension study.

Journal: Journal of hypertension 20090301

Title: Effects of allisartan, a new AT(1) receptor blocker, on blood pressure and end-organ damage in hypertensive animals.

Journal: Acta pharmacologica Sinica 20090301

Title: Relationship between left atrial size and stroke in patients with sinus rhythm and preserved systolic function.

Journal: The Korean journal of internal medicine 20090301

Title: Review: renal protection by inhibition of the renin-angiotensin-aldosterone system.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20090301

Title: Local renin-angiotensin system regulates left ventricular hypertrophy induced by swimming training independent of circulating renin: a pharmacological study.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20090301

Title: [Effects of losartan on left ventricular hypertrophy and plasma transforming growth factor-beta1 in elderly patients with hypertension].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20090301

Title: Fixed-dose manidipine/delapril versus losartan/hydrochlorothiazide in hypertensive patients with type 2 diabetes and microalbuminuria.

Journal: Advances in therapy 20090301

Title: Impairment of the autoregulation of renal hemodynamics and of the pressure-natriuresis relationship precedes the development of hypertension in Cyp1a1-Ren-2 transgenic rats.

Journal: Journal of hypertension 20090301

Title: Beneficial effects of the combination of amlodipine and losartan for lowering blood pressure in spontaneously hypertensive rats.

Journal: Archives of pharmacal research 20090301

Title: [Changes of MMP-2,9 and TIMP-1 expressions in rats with pulmonary arterial hypertension after captopril and losartan interventions].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20090301

Title: Models of cardiovascular disease: measurement of antihypertensive activity in the conscious rat (SHR, DOCA-salt, and Goldblatt hypertension models).

Journal: Current protocols in pharmacology 20090301

Title: Microinjection of angiotensin II in the caudal ventrolateral medulla induces hyperalgesia.

Journal: Neuroscience 20090218

Title: Administration of angiotensin II, but not catecholamines, induces accumulation of lipids in the rat heart.

Journal: European journal of pharmacology 20090214

Title: Effect of the direct Renin inhibitor aliskiren, the Angiotensin receptor blocker losartan, or both on left ventricular mass in patients with hypertension and left ventricular hypertrophy.

Journal: Circulation 20090203

Title: Hyperbaric oxygen treatment improves GFR in rats with ischaemia/reperfusion renal injury: a possible role for the antioxidant/oxidant balance in the ischaemic kidney.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090201

Title: Activation of renin-angiotensin system induces osteoporosis independently of hypertension.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20090201

Title: Effects of high-dose simvastatin therapy on glucose metabolism and ectopic lipid deposition in nonobese type 2 diabetic patients.

Journal: Diabetes care 20090201

Title: Activation of renal renin-angiotensin system in upstream stimulatory factor 2 transgenic mice.

Journal: American journal of physiology. Renal physiology 20090201

Title: Renin dynamics in adipose tissue: adipose tissue control of local renin concentrations.

Journal: American journal of physiology. Endocrinology and metabolism 20090201

Title: Angiotensin-(1-7) activates growth-stimulatory pathways in human mesangial cells.

Journal: American journal of physiology. Renal physiology 20090201

Title: Renin-angiotensin system and alpha-adducin gene polymorphisms and their relation to responses to antihypertensive drugs: results from the GENRES study.

Journal: American journal of hypertension 20090201

Title: Regulation of T-cell function by endogenously produced angiotensin II.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20090201

Title: Design of combination angiotensin receptor blocker and angiotensin-converting enzyme inhibitor for treatment of diabetic nephropathy (VA NEPHRON-D).

Journal: Clinical journal of the American Society of Nephrology : CJASN 20090201

Title: Angiotensin II type 1 receptor-mediated reduction of angiotensin-converting enzyme 2 activity in the brain impairs baroreflex function in hypertensive mice.

Journal: Hypertension (Dallas, Tex. : 1979) 20090201

Title: [Multi-national clinical trial in circulatory disorders].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20090201

Title: Vascular and metabolic effects of angiotensin II receptor blockers.

Journal: Expert opinion on pharmacotherapy 20090201

Title: Effects of carvedilol, losartan and trimetazidin on functional parameters of isolated heart of rats at oxidative stress.

Journal: Georgian medical news 20090201

Title: Molecular imaging for efficacy of pharmacologic intervention in myocardial remodeling.

Journal: JACC. Cardiovascular imaging 20090201

Title: Anaesthetic Management for Cataract Surgery in VACTERL Syndrome Case Report.

Journal: Indian journal of anaesthesia 20090201

Title: TRPCs, GPCRs and the Bayliss effect.

Journal: The EMBO journal 20090107

Title: Short-term electrophysiological effects of losartan, bisoprolol, amlodipine, and hydrochlorothiazide in hypertensive men.

Journal: Annals of medicine 20090101

Title: Long-term effect of losartan administration on blood pressure, heart and structure of coronary artery of young spontaneously hypertensive rats.

Journal: Physiological research 20090101

Title: Determination of caveolin-1 in renal caveolar and non-caveolar fractions in experimental type 1 diabetes.

Journal: Physiological research 20090101

Title: Regulation of oxygen utilization by angiotensin II in chronic kidney disease.

Journal: Kidney international 20090101

Title: Effect of renin-angiotensin-aldosterone system inhibition, dietary sodium restriction, and/or diuretics on urinary kidney injury molecule 1 excretion in nondiabetic proteinuric kidney disease: a post hoc analysis of a randomized controlled trial.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20090101

Title: High-affinity interaction of sartans with H+/peptide transporters.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20090101

Title: A novel type of implantable and programmable infusion pump for small laboratory animals.

Journal: Journal of pharmacological and toxicological methods 20090101

Title: Liver is the site of splanchnic cortisol production in obese nondiabetic humans.

Journal: Diabetes 20090101

Title: Losartan, an antagonist of AT1 receptor for angiotensin II, attenuates lipopolysaccharide-induced acute lung injury in rat.

Journal: Archives of biochemistry and biophysics 20090101

Title: Regression of glomerular injury by losartan in experimental diabetic nephropathy.

Journal: Kidney international 20090101

Title: Angiotensin II induces vascular endothelial growth factor synthesis in mesenchymal stem cells.

Journal: Experimental cell research 20090101

Title: Angiotensin II-mediated vasodilation is reduced in adult spontaneously hypertensive rats despite enhanced expression of AT2 receptors.

Journal: Clinical and experimental pharmacology & physiology 20090101

Title: Blockade of AT1 receptor partially restores vasoreactivity, NOS expression, and superoxide levels in cerebral and carotid arteries of hindlimb unweighting rats.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20090101

Title: Olmesartan reduced microalbuminuria in Japanese subjects with type 2 diabetes.

Journal: Diabetes research and clinical practice 20090101

Title: Comparison of effects of amlodipine and angiotensin receptor blockers on the intima-media thickness of carotid arterial wall (AAA study: amlodipine vs. ARB in atherosclerosis study).

Journal: Diabetes research and clinical practice 20090101

Title: Erythropoietin levels in heart failure after an acute myocardial infarction: determinants, prognostic value, and the effects of captopril versus losartan.

Journal: American heart journal 20090101

Title: Prognostic importance of hemoglobin in hypertensive patients with electrocardiographic left ventricular hypertrophy: the Losartan Intervention For End point reduction in hypertension (LIFE) study.

Journal: American heart journal 20090101

Title: Inhibition of the renin-angiotensin system: is more better?

Journal: Kidney international 20090101

Title: Telmisartan is more effective than losartan in reducing proteinuria.

Journal: Kidney international 20090101

Title: Urotensin II-induced increase in myocardial distensibility is modulated by angiotensin II and endothelin-1.

Journal: Physiological research 20090101

Title: Kidney injury molecule 1: in search of biomarkers of chronic tubulointerstitial damage and disease progression.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20090101

Title: Standards of medical care in diabetes--2009.

Journal: Diabetes care 20090101

Title: Eplerenone decreases inflammatory foci in spontaneously hypertensive rat hearts with minimal effects on blood pressure.

Journal: Journal of cardiovascular pharmacology 20090101

Title: Role of angiotensin II in the response to endothelin-1 of goat cerebral arteries after ischemia-reperfusion.

Journal: Vascular pharmacology 20090101

Title: Angiotensin blockade prevents salt-induced injury of the renal circulation in spontaneously hypertensive rats.

Journal: American journal of nephrology 20090101

Title: Altered expression of Na+ transporters at the mRNA level in rat normal and hypertrophic myocardium.

Journal: Heart and vessels 20090101

Title: Cardiovascular outcomes in high-risk patients without heart failure treated with ARBs: a systematic review and meta-analysis.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20090101

Title: Metabolic consequences and vulnerability to diet-induced obesity in male mice under chronic social stress.

Journal: PloS one 20090101

Title: Cardiac autonomic neuropathy as a predictor of deterioration of the renal function in normoalbuminuric, normotensive patients with type 2 diabetes mellitus.

Journal: Journal of Korean medical science 20090101

Title: Roles of mitogen-activated protein kinases and angiotensin II in renal development.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20090101

Title: Myeloid-related protein 8/14 complex describes microcirculatory alterations in patients with type 2 diabetes and nephropathy.

Journal: Cardiovascular diabetology 20090101

Title: Comparison of therapies between fixed-dose telmisartan/hydrochlorothiazide and losartan/hydrochlorothiazide in patients with mild to moderate hypertension.

Journal: International heart journal 20090101

Title: Genetic polymorphisms and the risk of accelerated renal function decline in women.

Journal: PloS one 20090101

Title: Genetic polymorphisms of angiotensin-2 type 1 receptor and angiotensinogen and risk of renal dysfunction and coronary heart disease in type 2 diabetes mellitus.

Journal: BMC nephrology 20090101

Title: Blood pressure reduction, persistence and costs in the evaluation of antihypertensive drug treatment--a review.

Journal: Cardiovascular diabetology 20090101

Title: Analysis of published economic evaluations of angiotensin receptor blockers.

Journal: Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20090101

Title: Angiotensin II directly regulates intestinal epithelial NHE3 in Caco2BBE cells.

Journal: BMC physiology 20090101

Title: Effects of losartan pretreatment in an experimental model of ischemic acute kidney injury.

Journal: Nephron. Experimental nephrology 20090101

Title: Losartan decreases p42/44 MAPK signaling and preserves LZ+ MYPT1 expression.

Journal: PloS one 20090101

Title: Estimating the probability of stroke in Korean hypertensive patients visiting tertiary hospitals using a risk profile from the Framingham study.

Journal: BMC neurology 20090101

Title: The renin-angiotensin system modulates inflammatory processes in atherosclerosis: evidence from basic research and clinical studies.

Journal: Mediators of inflammation 20090101

Title: Losartan, an angiotensin-II type 1 receptor blocker, attenuates the liver fibrosis development of non-alcoholic steatohepatitis in the rat.

Journal: BMC research notes 20090101

Title: Candesartan cilexetil in the treatment of chronic heart failure.

Journal: Vascular health and risk management 20090101

Title: Arterial stiffness in insulin resistance: the role of nitric oxide and angiotensin II receptors.

Journal: Vascular health and risk management 20090101

Title: Results of the ONTARGET and TRANSCEND studies: an update and discussion.

Journal: Vascular health and risk management 20090101

Title: The effect of angiotensin receptor blockers on C-reactive protein and other circulating inflammatory indices in man.

Journal: Vascular health and risk management 20090101

Title: Effects of candesartan cilexetil on carotid remodeling in hypertensive diabetic patients: the MITEC study.

Journal: Vascular health and risk management 20090101

Title: Angiotensin receptor blockers for the reduction of proteinuria in diabetic patients with overt nephropathy: results from the AMADEO study.

Journal: Vascular health and risk management 20090101

Title: Effect of losartan on Doppler sonography indices in kidney transplant patients: a randomized clinical trial.

Journal: Vascular health and risk management 20090101

Title: [Immunomodulating, metabolic and cardioprotective effects of AT1-angiotensin receptors blocker losartan in patients with coronary heart disease and type 2 diabetes mellitus].

Journal: Terapevticheskii arkhiv 20090101

Title: Angiotensin II induces inflammatory response partly via toll-like receptor 4-dependent signaling pathway in vascular smooth muscle cells.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20090101

Title: Choice of ACE inhibitor combinations in hypertensive patients with type 2 diabetes: update after recent clinical trials.

Journal: Vascular health and risk management 20090101

Title: Role of aliskiren in cardio-renal protection and use in hypertensives with multiple risk factors.

Journal: Vascular health and risk management 20090101

Title: Effects of enalapril and losartan in left ventricular remodeling after acute myocardial infarction: a possible mechanism of prevention of cardiac events by angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in high-risk myocardial infarction.

Journal: Internal medicine (Tokyo, Japan) 20090101

Title: Impact of statins and ACE inhibitors on mortality after COPD exacerbations.

Journal: Respiratory research 20090101

Title: ACE (I/D) polymorphism and response to treatment in coronary artery disease: a comprehensive database and meta-analysis involving study quality evaluation.

Journal: BMC medical genetics 20090101

Title: Renin-angiotensin-aldosterone system in the elderly: rational use of aliskiren in managing hypertension.

Journal: Clinical interventions in aging 20090101

Title: [Involvement of angiotensin on adenosine-induced bronchial hyperreactivity].

Journal: Pneumologia (Bucharest, Romania) 20090101

Title: Radioligand binding assays: application of [(125)I]angiotensin II receptor binding.

Journal: Methods in molecular biology (Clifton, N.J.) 20090101

Title: Losartan counteracts the hyper-reactivity to angiotensin II and ROCK1 over-activation in aortas isolated from streptozotocin-injected diabetic rats.

Journal: Cardiovascular diabetology 20090101

Title: Influence of dual blockade of the renin-angiotensin system on thirst in hemodialysis patients.

Journal: Nephron. Clinical practice 20090101

Title: Pulse pressure, left ventricular function and cardiovascular events during antihypertensive treatment (the LIFE study).

Journal: Blood pressure 20090101

Title: Reversal of liver fibrosis.

Journal: Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 20090101

Title: Effects of losartan on fibrinolytic parameters and von Willebrand factor in Chinese subjects with hypertension: a comparative study versus atenolol.

Journal: The Journal of international medical research 20090101

Title: Antiproteinuric effect of angiotensin-converting enzyme inhibitors and an angiotensin II receptor blocker in patients with lupus nephritis.

Journal: The Journal of international medical research 20090101

Title: Excess of glucocorticoid induces cardiac dysfunction via activating angiotensin II pathway.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20090101

Title: Heme oxygenase-1 inducer hemin attenuates the progression of remnant kidney model.

Journal: Nephron. Experimental nephrology 20090101

Title: Pleiotropic effects of statins in atrial fibrillation patients: the evidence.

Journal: Vascular health and risk management 20090101

Title: Effect of centrally administered losartan on gastric and duodenal ulcers in rats.

Journal: Pharmacology 20090101

Title: Valsartan improves endothelial dysfunction in hypertension: a randomized, double-blind study.

Journal: Cardiovascular therapeutics 20090101

Title: Combination effects of enalapril and losartan on lipid peroxidation in the kidneys of KK-Ay/Ta mice.

Journal: Nephron. Experimental nephrology 20090101

Title: Biliary pancreatic diversion and laparoscopic adjustable gastric banding in morbid obesity: their long-term effects on metabolic syndrome and on cardiovascular parameters.

Journal: Cardiovascular diabetology 20090101

Title: High prevalence of undiagnosed chronic kidney disease among at-risk population in Kinshasa, the Democratic Republic of Congo.

Journal: BMC nephrology 20090101

Title: Serial evaluation of electrocardiographic left ventricular hypertrophy for prediction of risk in hypertensive patients.

Journal: Journal of electrocardiology 20090101

Title: Two dissimilar AT(1) agonists distinctively activate AT(1) receptors located on the luminal membrane of coronary endothelium.

Journal: Vascular pharmacology 20090101

Title: Irbesartan improves arterial compliance more than lisinopril.

Journal: Vascular health and risk management 20090101

Title: One-year renal and cardiac effects of bisoprolol versus losartan in recently diagnosed hypertensive patients: a randomized, double-blind study.

Journal: Clinical drug investigation 20090101

Title: Gout. Novel therapies for treatment of gout and hyperuricemia.

Journal: Arthritis research & therapy 20090101

Title: Angiotensins and Alzheimer's disease: a bench to bedside overview.

Journal: Alzheimer's research & therapy 20090101

Title: Ability to generate patient registries among practices with and without electronic health records.

Journal: Journal of medical Internet research 20090101

Title: A combined role of calcium channel blockers and angiotensin receptor blockers in stroke prevention.

Journal: Vascular health and risk management 20090101

Title: Restoration of podocyte structure and improvement of chronic renal disease in transgenic mice overexpressing renin.

Journal: PloS one 20090101

Title: Hypertensive target organ damage in Ghanaian civil servants with hypertension.

Journal: PloS one 20090101

Title: Primary prevention using losartan in type 1 diabetic patients significantly reduces retinopathy.

Journal: Cardiovascular journal of Africa 20090101

Title: Role of aliskiren in cardio-renal protection and use in hypertensives with multiple risk factors.

Journal: Therapeutics and clinical risk management 20090101

Title: A comparative study of the prevalence of hyperkalemia with the use of angiotensin-converting enzyme inhibitors versus angiotensin receptor blockers.

Journal: Therapeutics and clinical risk management 20090101

Title: Managing pediatric hepatitis C: current and emerging treatment options.

Journal: Therapeutics and clinical risk management 20090101

Title: Syncope caused by iatrogenic hyperkalemia.

Journal: Journal of cardiovascular medicine (Hagerstown, Md.) 20090101

Title: Gout. Hyperuricemia and cardiovascular disease: how strong is the evidence for a causal link?

Journal: Arthritis research & therapy 20090101

Title: [Inhibition of the renin angiotensin system in pregnancy and risk of fetal malformations].

Journal: La Pediatria medica e chirurgica : Medical and surgical pediatrics 20090101

Title: Cardiac sarcoidosis culminating in severe biventricular failure.

Journal: Case reports in medicine 20090101

Title: Cardiovascular effects of losartan and its relevant clinical application.

Journal: Current medicinal chemistry 20090101

Title: Losartan chemistry and its effects via AT1 mechanisms in the kidney.

Journal: Current medicinal chemistry 20090101

Title: Cardiovascular disease in patients with chronic kidney disease.

Journal: Vascular health and risk management 20090101

Title: Blood pressure goal achievement with olmesartan medoxomil-based treatment: additional analysis of the OLMEBEST study.

Journal: Vascular health and risk management 20090101

Title: Angiotensin II receptor blockers in the prevention of complications from atrial fibrillation.

Journal: Vascular health and risk management 20090101

Title: Drugs associated with more suicidal ideations are also associated with more suicide attempts.

Journal: PloS one 20090101

Title: Comparative study of vasodilators in an animal model of chronic volume overload caused by severe aortic regurgitation.

Journal: Circulation. Heart failure 20090101

Title: Diabetic nephropathy.

Journal: Diabetology & metabolic syndrome 20090101

Title: Kidney transplant in diabetic patients: modalities, indications and results.

Journal: Diabetology & metabolic syndrome 20090101

Title: [Treatment of patients with arterial hypertension and other stroke risk factors in clinical practice. The PROGNOS program].

Journal: Terapevticheskii arkhiv 20090101

Title: Animal models for clinical and gestational diabetes: maternal and fetal outcomes.

Journal: Diabetology & metabolic syndrome 20090101

Title: Management of hypertension in the elderly patient.

Journal: Clinical interventions in aging 20090101

Title: The role of urate and xanthine oxidase in vascular oxidative stress: future directions.

Journal: Therapeutics and clinical risk management 20090101

Title: Plasmodium vivax malaria: an unusual presentation.

Journal: Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine 20090101

Title: The influence of peptides from the angiotensin family on tyrosine kinase activity and cell viability in a human hormone-dependent prostate cancer line.

Journal: Endokrynologia Polska 20090101

Title: Effects of angiotensin II type-1 receptor blocker losartan on age-related cardiovascular risk in spontaneously hypertensive rats.

Journal: General physiology and biophysics 20090101

Title: Are angiotensin-converting enzyme inhibitors and angiotensin receptor blockers especially useful for cardiovascular protection?

Journal: Journal of the American Board of Family Medicine : JABFM 20090101

Title: Resting sinus heart rate and first degree av block: modifiable risk predictors or epiphenomena?

Journal: Indian pacing and electrophysiology journal 20090101

Title: [Effect of renin-angiotensin system inhibitors on the density of myocardial, pericardial and pulmonary rat mast cells under experimental heart failure].

Journal: Tsitologiia 20090101

Title: Insights in to the pathogenesis of axial spondyloarthropathy based on gene expression profiles.

Journal: Arthritis research & therapy 20090101

Title: The use of pre-operative imaging and intraoperative parathyroid hormone level to guide surgical management of tertiary hyperparathyroidism from X-linked hypophosphatemic rickets: a case report.

Journal: Cases journal 20090101

Title: The rationale and design of the antihypertensives and vascular, endothelial, and cognitive function (AVEC) trial in elderly hypertensives with early cognitive impairment: role of the renin angiotensin system inhibition.

Journal: BMC geriatrics 20090101

Title: A randomized trial comparing the effect of ramipril and losartan in survivors of ST-elevation myocardial infarction.

Journal: The Journal of international medical research 20090101

Title: Characterisation of CYP2C8, CYP2C9 and CYP2C19 polymorphisms in a Ghanaian population.

Journal: BMC medical genetics 20090101

Title: Protective effects of the angiotensin II receptor blocker losartan on cisplatin-induced kidney injury.

Journal: Chemotherapy 20090101

Title: Review of the treatment of acute coronary syndrome in elderly patients.

Journal: Clinical interventions in aging 20090101

Title: Mitigating micro-and macro-vascular complications of diabetes beginning in adolescence.

Journal: Vascular health and risk management 20090101

Title: Comparative assessment of angiotensin receptor blockers in different clinical settings.

Journal: Vascular health and risk management 20090101

Title: Significance of initial blood pressure and comorbidity for the efficacy of a fixed combination of an angiotensin receptor blocker and hydrochlorothiazide in clinical practice.

Journal: Vascular health and risk management 20090101

Title: Predictors of cardiovascular events in patients with hypertension and left ventricular hypertrophy: the Losartan Intervention for Endpoint reduction in hypertension study.

Journal: Blood pressure 20090101

Title: Angiotensin receptor blocker reduces proteinuria independently of blood pressure in children already treated with Angiotensin-converting enzyme inhibitors.

Journal: Kidney & blood pressure research 20090101

Title: Adolescent type 1 Diabetes Cardio-renal Intervention Trial (AdDIT).

Journal: BMC pediatrics 20090101

Title: The potential for xanthine oxidase inhibition in the prevention and treatment of cardiovascular and cerebrovascular disease.

Journal: Cardiovascular psychiatry and neurology 20090101

Title: Management of hypertension with fixed dose combinations of candesartan cilexetil and hydrochlorothiazide: patient perspectives and clinical utility.

Journal: Vascular health and risk management 20090101

Title: The right ventricle: biologic insights and response to disease.

Journal: Current cardiology reviews 20090101

Title: Effect of peptide and nonpeptide antagonists of angiotensin II receptors on noradrenaline release in hypothalamus of rats with angiotensin II-induced increase of water intake.

Journal: Pharmacological reports : PR 20090101

Title: What lies behind serum urate concentration? Insights from genetic and genomic studies.

Journal: Genome medicine 20090101

Title: Angioedema beyond histamine: an educational case series.

Journal: Acta clinica Belgica 20090101

Title: New spectrophotometric and fluorimetric methods for determination of fluoxetine in pharmaceutical formulations.

Journal: International journal of analytical chemistry 20090101

Title: New sensitive kinetic spectrophotometric methods for determination of omeprazole in dosage forms.

Journal: International journal of analytical chemistry 20090101

Title: Telmisartan: a different angiotensin II receptor blocker protecting a different population?

Journal: The Journal of international medical research 20090101

Title: Treatment of diabetic vasculopathy with rosiglitazone and ramipril: Hype or hope?

Journal: International journal of diabetes in developing countries 20090101

Title: PPAR/RXR Regulation of Fatty Acid Metabolism and Fatty Acid omega-Hydroxylase (CYP4) Isozymes: Implications for Prevention of Lipotoxicity in Fatty Liver Disease.

Journal: PPAR research 20090101

Title: RP-HPLC Estimation of Ramipril and Telmisartan in Tablets.

Journal: Indian journal of pharmaceutical sciences 20090101

Title: An evaluation of the efficacy of olmesartan medoxomil in Black patients with hypertension.

Journal: Journal of the American Society of Hypertension : JASH 20090101

Title: A pharmacovigilance study of antihypertensive medicines at a South delhi hospital.

Journal: Indian journal of pharmaceutical sciences 20090101

Title: Derivative and Q-analysis Spectrophotometric Methods for Estimation of Hydrochlorothiazide and Olmesartan Medoxomil in Tablets.

Journal: Indian journal of pharmaceutical sciences 20090101

Title: Simultaneous estimation of amlodipine besilate and olmesartan medoxomil in pharmaceutical dosage form.

Journal: Indian journal of pharmaceutical sciences 20090101

Title: Exforge (amlodipine/valsartan combination) in hypertension: the evidence of its therapeutic impact.

Journal: Core evidence 20090101

Title: Febuxostat: the evidence for its use in the treatment of hyperuricemia and gout.

Journal: Core evidence 20090101

Title: Is there an effective therapy available for non-alcoholic fatty liver disease?

Journal: F1000 medicine reports 20090101

Title: Combination therapy of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers in chronic kidney disease.

Journal: F1000 medicine reports 20090101

Title: Simultaneous spectrophotometric estimation of Hydrochlorothiazide, Atenolol and Losartan potassium in tablet dosage form.

Journal: Hindustan antibiotics bulletin 20090101

Title: Telmisartan as a peroxisome proliferator-activated receptor-γ ligand is a new target in the treatment of human renal cell carcinoma.

Journal: Molecular medicine reports 20090101

Title: Effects of antihypertensive drugs on carotid intima-media thickness: Focus on angiotensin II receptor blockers. A review of randomized, controlled trials.

Journal: Integrated blood pressure control 20090101

Title: Current concepts in combination therapy for the treatment of hypertension: combined calcium channel blockers and RAAS inhibitors.

Journal: Integrated blood pressure control 20090101

Title: Angiotensin II augments renal vasoconstriction via AT1 receptors in L-NAME-induced hypertensive rats.

Journal: Proceedings of the Western Pharmacology Society 20090101

Title: Angiotensin II pressor response in the L-NAME-induced hypertensive pithed rat: role of the AT1 receptor.

Journal: Proceedings of the Western Pharmacology Society 20090101

Title: Analysis of nine drugs and their cytochrome P450-specific probe metabolites from urine by liquid chromatography-tandem mass spectrometry utilizing sub 2 microm particle size column.

Journal: Journal of chromatography. A 20081226

Title: Apoptosis-dependent acute pulmonary injury after intratracheal instillation of angiotensin II.

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20081225

Title: Synthesis and biological activities of novel nonpeptide angiotensin II receptor antagonists based on benzimidazole derivatives bearing a heterocyclic ring.

Journal: Bioorganic & medicinal chemistry 20081215

Title: Design, synthesis, and evaluation of 5-sulfamoyl benzimidazole derivatives as novel angiotensin II receptor antagonists.

Journal: Bioorganic & medicinal chemistry 20081215

Title: Molecular imaging of interstitial alterations in remodeling myocardium after myocardial infarction.

Journal: Journal of the American College of Cardiology 20081209

Title: Gq-coupled receptors as mechanosensors mediating myogenic vasoconstriction.

Journal: The EMBO journal 20081203

Title: Opposed effects of prostaglandin E2 on perfusion of rat renal cortex and medulla: interactions with the renin-angiotensin system.

Journal: Experimental physiology 20081201

Title: Angiotensin II type 1 receptor blocker ameliorates uncoupled endothelial nitric oxide synthase in rats with experimental diabetic nephropathy.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20081201

Title: Cost-effectiveness of irbesartan/hydrochlorothiazide in patients with hypertension: an economic evaluation for Sweden.

Journal: Journal of human hypertension 20081201

Title: N-acetylcysteine abolishes the protective effect of losartan against left ventricular remodeling in cardiomyopathy hamster.

Journal: Antioxidants & redox signaling 20081201

Title: The effect of different treatment strategies on left atrial size in patients with lone paroxysmal atrial fibrillation-a prospective cohort study.

Journal: Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 20081201

Title: Intracellular angiotensin II production in diabetic rats is correlated with cardiomyocyte apoptosis, oxidative stress, and cardiac fibrosis.

Journal: Diabetes 20081201

Title: Loss of vitamin D receptor produces polyuria by increasing thirst.

Journal: Journal of the American Society of Nephrology : JASN 20081201

Title: Proteinuria lowering needs a multifactorial and individualized approach to halt progression of renal disease.

Journal: Nature clinical practice. Nephrology 20081201

Title: Dual inhibition with losartan and aliskiren: a promising therapeutic option for type 2 diabetic nephropathy?

Journal: Nature clinical practice. Nephrology 20081201

Title: Regulation of ACE2 in cardiac myocytes and fibroblasts.

Journal: American journal of physiology. Heart and circulatory physiology 20081201

Title: Autoantibodies to the angiotensin type I receptor in response to placental ischemia and tumor necrosis factor alpha in pregnant rats.

Journal: Hypertension (Dallas, Tex. : 1979) 20081201

Title: Aliskiren combined with losartan: Thor's hammer or Sigurd's sword?

Journal: Current hypertension reports 20081201

Title: (Pro)renin receptor promotes choroidal neovascularization by activating its signal transduction and tissue renin-angiotensin system.

Journal: The American journal of pathology 20081201

Title: The role of angiotensin II type 1a receptor on intestinal epithelial cells following small bowel resection in a mouse model.

Journal: Pediatric surgery international 20081201

Title: Treatment for genetic diseases.

Journal: Current opinion in pediatrics 20081201

Title: Diabetic state, high plasma insulin and angiotensin II combine to augment endothelin-1-induced vasoconstriction via ETA receptors and ERK.

Journal: British journal of pharmacology 20081201

Title: The relationship between heart rate reserve and oxygen uptake reserve in heart failure patients on optimized and non-optimized beta-blocker therapy.

Journal: Clinics (Sao Paulo, Brazil) 20081201

Title: [A case of giant cell microscopic colitis?].

Journal: Annales de pathologie 20081201

Title: [Mechanisms of losartan for inhibition of myocardial fibrosis following myocardial infarction in rats].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20081201

Title: Expression of NAD(P)H oxidase subunits and their contribution to cardiovascular damage in aldosterone/salt-induced hypertensive rat.

Journal: Journal of Korean medical science 20081201

Title: The left atrium, atrial fibrillation, and the risk of stroke in hypertensive patients with left ventricular hypertrophy.

Journal: Therapeutic advances in cardiovascular disease 20081201

Title: Telmisartan and carotid intima-media thickness regression: a class effect of angiotensin-receptor blockers?

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20081201

Title: High dose Losartan and ACE gene polymorphism in IgA nephritis.

Journal: Genomic medicine 20081201

Title: Renin inhibition with aliskiren in hypertension: focus on aliskiren/hydrochlorothiazide combination therapy.

Journal: Vascular health and risk management 20081201

Title: Clinical efficacy and safety of olmesartan/hydrochlorothiazide combination therapy in patients with essential hypertension.

Journal: Vascular health and risk management 20081201

Title: Long-acting nifedipine in the management of the hypertensive patient.

Journal: Vascular health and risk management 20081201

Title: Pathophysiology of placentation abnormalities in pregnancy-induced hypertension.

Journal: Vascular health and risk management 20081201

Title: The evolution of systolic blood pressure as a strong predictor of cardiovascular risk and the effectiveness of fixed-dose ARB/CCB combinations in lowering levels of this preferential target.

Journal: Vascular health and risk management 20081201

Title: Targeting liver myofibroblasts: a novel approach in anti-fibrogenic therapy.

Journal: Hepatology international 20081201

Title: Safety and efficacy of enzyme replacement therapy in the nephropathy of Fabry disease.

Journal: Biologics : targets & therapy 20081201

Title: Slower heart rates for healthy hearts: time to redefine tachycardia?

Journal: Circulation. Arrhythmia and electrophysiology 20081201

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