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115-86-6,MFCD00003031
Catalog No.:AA000FHK

115-86-6 | Phosphoric acid, triphenyl ester

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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA000FHK
Chemical Name:
Phosphoric acid, triphenyl ester
CAS Number:
115-86-6
Molecular Formula:
C18H15O4P
Molecular Weight:
326.2831
MDL Number:
MFCD00003031
SMILES:
O=P(Oc1ccccc1)(Oc1ccccc1)Oc1ccccc1
NSC Number:
57868
Properties
Properties
 
BP:
412.4°C at 760 mmHg  
Form:
Solid  
MP:
48-50 °C(lit.)  
Refractive Index:
1.563  
Solubility:
H2O: soluble0.0019g/L at 20°C  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
325  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
4  
Rotatable Bond Count:
6  
XLogP3:
4.6  

Literature

Title: Disruption of Nuclear Receptor Signaling Alters Triphenyl Phosphate-Induced Cardiotoxicity in Zebrafish Embryos.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20180501

Title: Organophosphate Flame-Retardants Alter Adult Mouse Homeostasis and Gene Expression in a Sex-Dependent Manner Potentially Through Interactions With ERα.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20180301

Title: Adipogenic Effects and Gene Expression Profiling of Firemaster® 550 Components in Human Primary Preadipocytes.

Journal: Environmental health perspectives 20170901

Title: Activation of Peroxisome Proliferator-Activated Receptor Gamma and Disruption of Progesterone Synthesis of 2-Ethylhexyl Diphenyl Phosphate in Human Placental Choriocarcinoma Cells: Comparison with Triphenyl Phosphate.

Journal: Environmental science & technology 20170404

Title: Triphenyl phosphate enhances adipogenic differentiation, glucose uptake and lipolysis via endocrine and noradrenergic mechanisms.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20170401

Title: Developmental neurotoxicity of organophosphate flame retardants in early life stages of Japanese medaka (Oryzias latipes).

Journal: Environmental toxicology and chemistry 20161201

Title: Long-term exposure to triphenylphosphate alters hormone balance and HPG, HPI, and HPT gene expression in zebrafish (Danio rerio).

Journal: Environmental toxicology and chemistry 20160901

Title: Use of a Novel Double-Crested Cormorant ToxChip PCR Array and the EROD Assay to Determine Effects of Environmental Contaminants in Primary Hepatocytes.

Journal: Environmental science & technology 20160315

Title: Effects of primary metabolites of organophosphate flame retardants on transcriptional activity via human nuclear receptors.

Journal: Toxicology letters 20160314

Title: Targeting neurotrophic factors and their receptors, but not cholinesterase or neurotransmitter, in the neurotoxicity of TDCPP in Chinese rare minnow adults (Gobiocypris rarus).

Journal: Environmental pollution (Barking, Essex : 1987) 20160101

Title: TPhP exposure disturbs carbohydrate metabolism, lipid metabolism, and the DNA damage repair system in zebrafish liver.

Journal: Scientific reports 20160101

Title: TPP and TCEP induce oxidative stress and alter steroidogenesis in TM3 Leydig cells.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20151101

Title: Improved assays for xenosensor activation based on reverse transfection.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20151001

Title: Activation of Human Peroxisome Proliferator-Activated Nuclear Receptors (PPARγ1) by Semi-Volatile Compounds (SVOCs) and Chemical Mixtures in Indoor Dust.

Journal: Environmental science & technology 20150818

Title: Exposure of male mice to two kinds of organophosphate flame retardants (OPFRs) induced oxidative stress and endocrine disruption.

Journal: Environmental toxicology and pharmacology 20150701

Title: Aryl organophosphate flame retardants induced cardiotoxicity during zebrafish embryogenesis: by disturbing expression of the transcriptional regulators.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20150401

Title: Thyroid disruption by triphenyl phosphate, an organophosphate flame retardant, in zebrafish (Danio rerio) embryos/larvae, and in GH3 and FRTL-5 cell lines.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20150301

Title: Characterizing the peroxisome proliferator-activated receptor (PPARγ) ligand binding potential of several major flame retardants, their metabolites, and chemical mixtures in house dust.

Journal: Environmental health perspectives 20150201

Title: Affinities of organophosphate flame retardants to tumor suppressor gene p53: an integrated in vitro and in silico study.

Journal: Toxicology letters 20150122

Title: Rapid in vitro metabolism of the flame retardant triphenyl phosphate and effects on cytotoxicity and mRNA expression in chicken embryonic hepatocytes.

Journal: Environmental science & technology 20141118

Title: Determination and prediction of the binding interaction between organophosphate flame retardants and p53.

Journal: Chemical research in toxicology 20141117

Title: Ligand binding and activation of PPARγ by Firemaster® 550: effects on adipogenesis and osteogenesis in vitro.

Journal: Environmental health perspectives 20141101

Title: Potential estrogenic effects of phosphorus-containing flame retardants.

Journal: Environmental science & technology 20140617

Title: Organophosphorus flame retardants inhibit specific liver carboxylesterases and cause serum hypertriglyceridemia.

Journal: ACS chemical biology 20140516

Title: In vitro endocrine disruption potential of organophosphate flame retardants via human nuclear receptors.

Journal: Toxicology 20131206

Title: Unique and highly selective anticytomegalovirus activities of artemisinin-derived dimer diphenyl phosphate stem from combination of dimer unit and a diphenyl phosphate moiety.

Journal: Antimicrobial agents and chemotherapy 20130901

Title: Effects of TDCPP or TPP on gene transcriptions and hormones of HPG axis, and their consequences on reproduction in adult zebrafish (Danio rerio).

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20130615

Title: Aryl phosphate esters within a major PentaBDE replacement product induce cardiotoxicity in developing zebrafish embryos: potential role of the aryl hydrocarbon receptor.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20130501

Title: Similarities in the endocrine-disrupting potencies of indoor dust and flame retardants by using human osteosarcoma (U2OS) cell-based reporter gene assays.

Journal: Environmental science & technology 20130319

Title: Effects of tris(1,3-dichloro-2-propyl) phosphate and triphenyl phosphate on receptor-associated mRNA expression in zebrafish embryos/larvae.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20130315

Title: Gas chromatographic determination of phosphate-based flame retardants in styrene-based polymers from waste electrical and electronic equipment.

Journal: Journal of chromatography. A 20121102

Title: Modulation of human α4β2 nicotinic acetylcholine receptors by brominated and halogen-free flame retardants as a measure for in vitro neurotoxicity.

Journal: Toxicology letters 20120903

Title: Occurrence of alternative flame retardants in indoor dust from New Zealand: indoor sources and human exposure assessment.

Journal: Chemosphere 20120901

Title: Concentrations of organophosphate esters and brominated flame retardants in German indoor dust samples.

Journal: Journal of environmental monitoring : JEM 20120901

Title: Phosphorus flame retardants: properties, production, environmental occurrence, toxicity and analysis.

Journal: Chemosphere 20120801

Title: Endocrine disruption potentials of organophosphate flame retardants and related mechanisms in H295R and MVLN cell lines and in zebrafish.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20120615

Title: Assessment of human exposure to indoor organic contaminants via dust ingestion in Pakistan.

Journal: Indoor air 20120601

Title: The involvement of cytochrome P450 monooxygenases in methanol elimination in Drosophila melanogaster larvae.

Journal: Archives of insect biochemistry and physiology 20120401

Title: Chlorantraniliprole susceptibility in Leptinotarsa decemlineata in the north Xinjiang Uygur autonomous region in China.

Journal: Journal of economic entomology 20120401

Title: Organophosphorus flame retardants and plasticizers in airborne particles over the Northern Pacific and Indian Ocean toward the Polar Regions: evidence for global occurrence.

Journal: Environmental science & technology 20120320

Title: Utilization of internal standard response factors to estimate the concentration of organic compounds leached from pharmaceutical packaging systems and application of such estimated concentrations to safety assessment.

Journal: Journal of chromatographic science 20120301

Title: Multi-residue method for the determination of brominated and organophosphate flame retardants in indoor dust.

Journal: Talanta 20120130

Title: Microarray analysis of gene regulations and potential association with acephate-resistance and fitness cost in Lygus lineolaris.

Journal: PloS one 20120101

Title: Consideration of emerging pollutants in groundwater-based reuse concepts.

Journal: Water science and technology : a journal of the International Association on Water Pollution Research 20120101

Title: Levels and distribution of organophosphorus flame retardants and plasticizers in fishes from Manila Bay, the Philippines.

Journal: Environmental pollution (Barking, Essex : 1987) 20111201

Title: N,N'-(Ethane-1,2-diyldi-o-phenyl-ene)bis-(pyridine-2-carboxamide).

Journal: Acta crystallographica. Section E, Structure reports online 20111101

Title: Delineating poly(aniline) redox chemistry by using tailored oligo(aryleneamine)s: towards oligo(aniline)-based organic semiconductors with tunable optoelectronic properties.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20111024

Title: Analysis of the flame retardant metabolites bis(1,3-dichloro-2-propyl) phosphate (BDCPP) and diphenyl phosphate (DPP) in urine using liquid chromatography-tandem mass spectrometry.

Journal: Analytical and bioanalytical chemistry 20111001

Title: Brominated and organophosphate flame retardants in selected consumer products on the Japanese market in 2008.

Journal: Journal of hazardous materials 20110915

Title: Identification of flame retardants in polyurethane foam collected from baby products.

Journal: Environmental science & technology 20110615

Title: Cross-resistance of bisultap resistant strain of Nilaparvata lugens and its biochemical mechanism.

Journal: Journal of economic entomology 20110201

Title: Exposure to airborne organophosphates originating from hydraulic and turbine oils among aviation technicians and loaders.

Journal: Journal of environmental monitoring : JEM 20101201

Title: Cross-resistance and possible mechanisms of chlorpyrifos resistance in Laodelphax striatellus (Fallén).

Journal: Pest management science 20101001

Title: Insecticide resistance status of Colorado potato beetle (Coleoptera: Chrysomelidae) adults in northern Xinjiang Uygur autonomous region.

Journal: Journal of economic entomology 20100801

Title: Materials recovery from waste printed circuit boards by supercritical methanol.

Journal: Journal of hazardous materials 20100615

Title: Organophosphorus flame retardants and plasticizers in marine and fresh water biota and in human milk.

Journal: Journal of environmental monitoring : JEM 20100401

Title: Methanol metabolism in the Asian corn borer, Ostrinia furnacalis (Guenée) (Lepidoptera: Pyralidae).

Journal: Journal of insect physiology 20100301

Title: Cross-resistance study and biochemical mechanisms of thiamethoxam resistance in B-biotype Bemisia tabaci (Hemiptera: Aleyrodidae).

Journal: Pest management science 20100301

Title: House dust concentrations of organophosphate flame retardants in relation to hormone levels and semen quality parameters.

Journal: Environmental health perspectives 20100301

Title: Endocrine damper? Flame retardants linked to male hormone, sperm count changes.

Journal: Environmental health perspectives 20100301

Title: Dynamic non-equilibrium SPME combined with GC, PICI, and ion trap MS for determination of organophosphate esters in air.

Journal: Analytical and bioanalytical chemistry 20100101

Title: [Resistance mechanisms of Spodoptera exigua (Hübner) to fenvalerate and alpha-cypermethrin].

Journal: Ying yong sheng tai xue bao = The journal of applied ecology 20100101

Title: Determination of multiresidue pesticides in green tea by using a modified QuEChERS extraction and ion-trap gas chromatography/mass spectrometry.

Journal: Journal of AOAC International 20100101

Title: Staggered larval time-to-hatch and insecticide resistance in the major malaria vector Anopheles gambiae S form.

Journal: Malaria journal 20100101

Title: Toxicology in the fast lane: application of high-throughput bioassays to detect modulation of key enzymes and receptors.

Journal: Environmental health perspectives 20091201

Title: Determination of organic micro-pollutants such as personal care products, plasticizers and flame retardants in sludge.

Journal: Analytical and bioanalytical chemistry 20091101

Title: Detection of organophosphate flame retardants in furniture foam and U.S. house dust.

Journal: Environmental science & technology 20091001

Title: Effects of spinosad on Helicoverpa armigera (Lepidoptera: Noctuidae) from China: tolerance status, synergism and enzymatic responses.

Journal: Pest management science 20090901

Title: Mechanisms of organophosphate resistance in a field population of oriental migratory locust, Locusta migratoria manilensis (Meyen).

Journal: Archives of insect biochemistry and physiology 20090501

Title: [Determination of 29 pesticide residues in tobacco by gas chromatography-electron impact ionization mass spectrometry].

Journal: Se pu = Chinese journal of chromatography 20090301

Title: Respiratory and dermal exposure to organophosphorus flame retardants and tetrabromobisphenol A at five work environments.

Journal: Environmental science & technology 20090201

Title: Environmental impact of flame retardants (persistence and biodegradability).

Journal: International journal of environmental research and public health 20090201

Title: Insights into ligand-elicited activation of human constitutive androstane receptor based on novel agonists and three-dimensional quantitative structure-activity relationship.

Journal: Journal of medicinal chemistry 20081127

Title: Differential response to diazinon and coumaphos in a strain of Boophilus microplus (Acari: Ixodidae) collected in Mexico.

Journal: Journal of medical entomology 20080901

Title: Fast gas chromatography for pesticide residues analysis using analyte protectants.

Journal: Journal of chromatography. A 20080404

Title: Multiple insecticide resistance mechanisms involving metabolic changes and insensitive target sites selected in anopheline vectors of malaria in Sri Lanka.

Journal: Malaria journal 20080101

Title: Identification of estrogenic compounds emitted from the combustion of computer printed circuit boards in electronic waste.

Journal: Environmental science & technology 20071215

Title: Adapting an ambient monitoring program to the challenge of managing emerging pollutants in the San Francisco Estuary.

Journal: Environmental research 20070901

Title: Differential response of Mono Mac 6, BEAS-2B, and Jurkat cells to indoor dust.

Journal: Environmental health perspectives 20070901

Title: Wittig reactions in water media employing stabilized ylides with aldehydes. Synthesis of alpha,beta-unsaturated esters from mixing aldehydes, alpha-bromoesters, and Ph3P in aqueous NaHCO3.

Journal: The Journal of organic chemistry 20070706

Title: Scrubbing ions with molecules: kinetic studies of chemical noise reduction in mass spectrometry using ion-molecule reactions with dimethyl disulfide.

Journal: Analytical chemistry 20070601

Title: Insecticide toxicity and synergism by enzyme inhibitors in 18 species of pest insect and natural enemies in crucifer vegetable crops.

Journal: Pest management science 20070501

Title: Attenuated total reflection surface-enhanced infrared absorption microspectroscopy for identification of small thin layers on material surfaces.

Journal: Applied spectroscopy 20070301

Title: Indoor organophosphate and polybrominated flame retardants in Tokyo.

Journal: Indoor air 20070201

Title: Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.

Journal: Journal of molecular graphics & modelling 20061101

Title: Role of kdr and esterase-mediated metabolism in pyrethroid-resistant populations of Haematobia irritans irritans (Diptera: Muscidae) in Brazil.

Journal: Journal of medical entomology 20060901

Title: On the role of frustration on the glass transition and polyamorphism of mesoscopically heterophase liquids.

Journal: The Journal of chemical physics 20060814

Title: Contact allergy to triphenyl phosphate: probable cross-reactivity to triphenyl phosphite present in an EN46001 System 22 clear oxygen facemask.

Journal: Contact dermatitis 20060501

Title: Elimination of organophosphate ester flame retardants and plasticizers in drinking water purification.

Journal: Water research 20060201

Title: Five-coordinate aluminum bromides: synthesis, structure, cation formation, and cleavage of phosphate ester bonds.

Journal: Journal of the American Chemical Society 20060201

Title: Determination of phosphoric acid triesters in human plasma using solid-phase microextraction and gas chromatography coupled to inductively coupled plasma mass spectrometry.

Journal: Journal of chromatography. A 20060127

Title: Traffic as a source of organophosphorus flame retardants and plasticizers in snow.

Journal: Environmental science & technology 20050515

Title: Effects of synergists on toxicity of six insecticides in parasitoid Diaeretiella rapae (Hymenoptera: Aphidiidae).

Journal: Journal of economic entomology 20041201

Title: Investigation of matrix effects of urine on a molecularly imprinted solid-phase extraction.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041125

Title: Exposure to phthalate esters from indoor environment.

Journal: Journal of exposure analysis and environmental epidemiology 20041101

Title: Organophosphate flame retardants and plasticizers in indoor air.

Journal: Chemosphere 20041101

Title: Enhanced esterase gene expression and activity in a malathion-resistant strain of the tarnished plant bug, Lygus lineolaris.

Journal: Insect biochemistry and molecular biology 20041101

Title: Organophosphorus flame retardants and plasticisers in surface waters.

Journal: The Science of the total environment 20041001

Title: Fenpyroximate resistance in Tetranychus urticae (Acari: Tetranychidae): cross-resistance and biochemical resistance mechanisms.

Journal: Pest management science 20041001

Title: Organophosphate flame retardants and plasticisers in wastewater treatment plants.

Journal: Journal of environmental monitoring : JEM 20040701

Title: Detection and characterization of amitraz resistance in the southern cattle tick, Boophilus microplus (Acari: Ixodidae).

Journal: Journal of medical entomology 20040301

Title: Determination of a flame retardant hydrolysis product in human urine by SPE and LC-MS. Comparison of molecularly imprinted solid-phase extraction with a mixed-mode anion exchanger.

Journal: Analytical and bioanalytical chemistry 20040101

Title: Effects of triaryl phosphates on mouse and human nuclear receptors.

Journal: Biochemical pharmacology 20040101

Title: Isolation of aryl-phosphate ester-degrading bacterium from leachate of a sea-based waste disposal site.

Journal: Journal of bioscience and bioengineering 20040101

Title: Screening of organophosphorus compounds and their distribution in various indoor environments.

Journal: Chemosphere 20031201

Title: Estimation of organophosphoric acid triesters in soft polyurethane foam using a concentrated sulfuric acid dissolution technique and gas chromatography with flame photometric detection.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20031201

Title: Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor.

Journal: Chemical research in toxicology 20031001

Title: Miniaturized dynamic liquid-liquid extraction of organophosphate triesters from blood plasma using the hollow fibre-based XT-tube extractor.

Journal: Analytical and bioanalytical chemistry 20030901

Title: Resistance to coumaphos and diazinon in Boophilus microplus (Acari: Ixodidae) and evidence for the involvement of an oxidative detoxification mechanism.

Journal: Journal of medical entomology 20030701

Title: Quantitative determination of loadings and oxidation products of polystyrene-bound phosphines using 31p MAS NMR.

Journal: Journal of combinatorial chemistry 20030101

Title: Degradation of organophosphoric esters in leachate from a sea-based solid waste disposal site.

Journal: Chemosphere 20020701

Title: Insecticide use and organophosphate resistance in the coffee leaf miner Leucoptera coffeella (Lepidoptera: Lyonetiidae).

Journal: Bulletin of entomological research 20020601

Title: In vitro detection of acaricide resistance in Boophilus microplus (Acari: Ixodidae).

Journal: Experimental & applied acarology 20020101

Title: Synthesis and evaluation of molecularly imprinted polymers for extracting hydrolysis products of organophosphate flame retardants.

Journal: Journal of chromatography. A 20011214

Title: Regioselective oxygenations of s-trans dienes, silyl dienol ethers (SDEs), by triphenyl phosphite ozonide (TPPO) and its mechanistic study.

Journal: The Journal of organic chemistry 20010518

Title: Development of a microporous membrane liquid-liquid extractor for organophosphate esters in human blood plasma: identification of triphenyl phosphate and octyl diphenyl phosphate in donor plasma.

Journal: Journal of chromatography. B, Biomedical sciences and applications 20010505

Title: Structure-activity relationships for a large diverse set of natural, synthetic, and environmental estrogens.

Journal: Chemical research in toxicology 20010301

Title: Characterization of acaricide resistance in Rhipicephalus sanguineus (latreille) (Acari: Ixodidae) collected from the Corozal Army Veterinary Quarantine Center, Panama.

Journal: Journal of medical entomology 20010301

Title: Flame retardants in indoor air at an electronics recycling plant and at other work environments.

Journal: Environmental science & technology 20010201

Title: New method for determination of ten pesticides in human blood.

Journal: Journal of AOAC International 20010101

Title: Comparative susceptibility and possible detoxification mechanisms for selected miticides in banks grass mite and two-spotted spider mite (Acari: Tetranychidae).

Journal: Experimental & applied acarology 20010101

Title: A subchronic toxicity study of Phosflex 51B in Sprague-Dawley rats.

Journal: International journal of toxicology 20010101

Title: Benzene-specific increase in leukocyte alkaline phosphatase activity in rats exposed to vapors of various organic solvents.

Journal: Journal of toxicology and environmental health 19860101

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Tags:115-86-6 Molecular Formula|115-86-6 MDL|115-86-6 SMILES|115-86-6 Phosphoric acid, triphenyl ester |Organic_Building_Blocks