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1162-53-4,MFCD00046219
Catalog No.:AA000BTB

1162-53-4 | Pregna-5,16-dien-20-one, 3-hydroxy-, (3b)-

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Purity
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5mg
>98%(HPLC)
in stock  
$66.00   $46.00
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25mg
>98%(HPLC)
in stock  
$161.00   $113.00
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100mg
>98%(HPLC)
in stock  
$407.00   $285.00
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1g
98%
in stock  
$2,731.00   $1,912.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA000BTB
Chemical Name:
Pregna-5,16-dien-20-one, 3-hydroxy-, (3b)-
CAS Number:
1162-53-4
Molecular Formula:
C21H30O2
Molecular Weight:
314.4617
MDL Number:
MFCD00046219
SMILES:
O[C@H]1CC[C@]2(C(=CC[C@@H]3[C@@H]2CC[C@]2([C@H]3CC=C2C(=O)C)C)C1)C
NSC Number:
15467
Properties
Properties
 
Form:
Solid  
MP:
205-210°C  
Storage:
Room Temperature;  

Computed Properties
 
Complexity:
601  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
6  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
3.9  

Literature

Title: Dose escalation pharmacokinetics and lipid lowering activity of a novel farnesoid X receptor modulator: 16-Dehydropregnenolone.

Journal: Indian journal of pharmacology 20120101

Title: A Validated Reverse Phase HPLC Analytical Method for Quantitation of Glycoalkaloids in Solanum lycocarpum and Its Extracts.

Journal: Journal of analytical methods in chemistry 20120101

Title: Activation of ATM-Chk2 by 16-dehydropregnenolone induces G1 phase arrest and apoptosis in HeLa cells.

Journal: Journal of Asian natural products research 20120101

Title: Aza-annulation on the 16-dehydropregnenolone, via tandem intermolecular aldol process and intramolecular Michael addition.

Journal: Bioorganic & medicinal chemistry letters 20110415

Title: Preclinical pharmacokinetics, dose proportionality, gender difference and protein binding study of 16-dehydropregnenolone, an antihyperlipidemic agent, in rats.

Journal: The Journal of pharmacy and pharmacology 20110101

Title: In vivo and in vitro effect of novel 4,16-pregnadiene-6,20-dione derivatives, as 5alpha-reductase inhibitors.

Journal: The Journal of steroid biochemistry and molecular biology 20080901

Title: Cytotoxic constituents from Solanum lyratum.

Journal: Archives of pharmacal research 20060201

Title: A sensitive and selective HPLC/ESI-MS/MS assay for the simultaneous quantification of 16-dehydropregnenolone and its major metabolites in rabbit plasma.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060102

Title: Synthesis of some new steroidal [16alpha,17alpha-d]-isoxazolines.

Journal: Steroids 20050701

Title: HPLC-UV method development and validation for 16-dehydropregnenolone, a novel oral hypolipidaemic agent, in rat biological matrices for application to pharmacokinetic studies.

Journal: Journal of pharmaceutical and biomedical analysis 20031124

Title: Development of an enzyme immunoassay for serum 16-dehydropregnenolone.

Journal: Biological & pharmaceutical bulletin 20010801

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SDS
Tags:1162-53-4 Molecular Formula|1162-53-4 MDL|1162-53-4 SMILES|1162-53-4 Pregna-5,16-dien-20-one, 3-hydroxy-, (3b)-