Home Other Building Blocks 117-99-7
117-99-7,MFCD00002216
Catalog No.:AA000DGD

117-99-7 | 2-Hydroxybenzophenone

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Purity
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1g
95%
in stock  
$16.00   $11.00
- +
5g
95%
in stock  
$19.00   $14.00
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10g
95%
in stock  
$37.00   $26.00
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25g
95%
in stock  
$92.00   $64.00
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100g
95%
in stock  
$365.00   $256.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA000DGD
Chemical Name:
2-Hydroxybenzophenone
CAS Number:
117-99-7
Molecular Formula:
C13H10O2
Molecular Weight:
198.2173
MDL Number:
MFCD00002216
SMILES:
Oc1ccccc1C(=O)c1ccccc1
NSC Number:
623
Properties
Properties
 
BP:
171-173°C at 760 mmHg  
Form:
Solid  
MP:
37-39 °C  
Refractive Index:
1.5954 (estimate)  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
219  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
XLogP3:
3.5  

Downstream Synthesis Route

[1]Soldi,Cristian;Lamb,KellanN.;Squitieri,RichardA.;Gonzlez-Lpez,Marcos;DiMaso,MichaelJ.;Shaw,JaredT.[JournaloftheAmericanChemicalSociety,2014,vol.136,#43,p.15142-15145]

[2]Lamb,KellanN.;Squitieri,RichardA.;Chintala,SrinivasaR.;Kwong,AdaJ.;Balmond,EdwardI.;Soldi,Cristian;Dmitrenko,Olga;CastiñeiraReis,Marta;Chung,Ryan;Addison,J.Bennett;Fettinger,JamesC.;Hein,JasonE.;Tantillo,DeanJ.;Fox,JosephM.;Shaw,JaredT.[Chemistry-AEuropeanJournal,2017,vol.23,#49,p.11843-11855]

[3]Bonnard;Meyer-Oulif[BulletindelaSocieteChimiquedeFrance,1931,vol.<4>49,p.1303,1305,1306]

[4]Liu,Wenbo;Chen,Ning;Yang,Xiaobo;Li,Lu;Li,Chao-Jun[ChemicalCommunications,2016,vol.52,#89,p.13120-13123]

[1]Patent:US2590813,1949,

[1]Choy,PuiYing;Kwong,FukYee[OrganicLetters,2013,vol.15,#2,p.270-273]

[2]Shan,Gang;Yang,Xinglin;Ma,Linlin;Rao,Yu[AngewandteChemie-InternationalEdition,2012,vol.51,#52,p.13070-13074][Angew.Chem.,2012,vol.124,#52,p.13247-13251,5]

[3]Shan,Gang;Han,Xuesong;Lin,Yun;Yu,Shanyou;Rao,Yu[OrganicandBiomolecularChemistry,2013,vol.11,#14,p.2318-2322]

[4]Massignan,Leonardo;Tan,Xuefeng;Meyer,TjarkH.;Kuniyil,Rositha;Messinis,AntonisM.;Ackermann,Lutz[AngewandteChemie-InternationalEdition,2020,vol.59,#8,p.3184-3189][Angew.Chem.,2020,vol.132,p.3210-3215,6]

[5]Rao,Yu[Synlett,2013,vol.24,#19,p.2472-2476]

[6]Mo,Fanyang;Trzepkowski,LouisJ.;Dong,Guangbin[AngewandteChemie-InternationalEdition,2012,vol.51,#52,p.13075-13079][Angew.Chem.,2012,vol.124,#52,p.13252-13256,5]

[7]CurrentPatentAssignee:DOWINC-US2839541,1955,A

[8]Trammell,Rachel;D'Amore,Lorenzo;Cordova,Alexandra;Polunin,Pavel;Xie,Nan;Siegler,MaximeA.;Belanzoni,Paola;Swart,Marcel;Garcia-Bosch,Isaac[InorganicChemistry,2019,vol.58,#11,p.7584-7592]

[1]Locationinpatent:experimentalpartKwon,EunMi;Kim,CheolGi;Goh,AhRa;Park,Jinseu;Jun,Jong-Gab[BulletinoftheKoreanChemicalSociety,2012,vol.33,#6,p.1939-1944]

[2]Cullinaneetal.[RecueildesTravauxChimiquesdesPays-Bas,1937,vol.56,p.627,629][JournaloftheChemicalSociety,1939,p.151]

[1]Sharshira,EssamMohamed;Shimada,Satoru;Okamura,Mutsuo;Hasegawa,Eietsu;Horaguchi,Takaaki[JournalofHeterocyclicChemistry,1996,vol.33,#6,p.1797-1805]

[2]Soldi,Cristian;Lamb,KellanN.;Squitieri,RichardA.;Gonzlez-Lpez,Marcos;DiMaso,MichaelJ.;Shaw,JaredT.[JournaloftheAmericanChemicalSociety,2014,vol.136,#43,p.15142-15145]

[3]Lamb,KellanN.;Squitieri,RichardA.;Chintala,SrinivasaR.;Kwong,AdaJ.;Balmond,EdwardI.;Soldi,Cristian;Dmitrenko,Olga;CastiñeiraReis,Marta;Chung,Ryan;Addison,J.Bennett;Fettinger,JamesC.;Hein,JasonE.;Tantillo,DeanJ.;Fox,JosephM.;Shaw,JaredT.[Chemistry-AEuropeanJournal,2017,vol.23,#49,p.11843-11855]

[4]Bonnard;Meyer-Oulif[BulletindelaSocieteChimiquedeFrance,1931,vol.<4>49,p.1303,1305,1306]

Literature

Title: Structure-activity relationships, ligand efficiency, and lipophilic efficiency profiles of benzophenone-type inhibitors of the multidrug transporter P-glycoprotein.

Journal: Journal of medicinal chemistry 20120412

Title: Pseudopolymorphism in hydroxybenzophenones: the dihydrate of 2,2',4,4'-tetrahydroxybenzophenone.

Journal: Acta crystallographica. Section C, Crystal structure communications 20120401

Title: 2-[(E)-Phen-yl(2-phenyl-hydrazin-1-yl-idene)meth-yl]phenol.

Journal: Acta crystallographica. Section E, Structure reports online 20120301

Title: 2-{[(4-{[(2-Hy-droxy-phen-yl)(phen-yl)methyl-idene]amino}-but-yl)imino](phen-yl)meth-yl}phenol.

Journal: Acta crystallographica. Section E, Structure reports online 20120201

Title: Epithelial proinflammatory response and curcumin-mediated protection from staphylococcal toxic shock syndrome toxin-1.

Journal: PloS one 20120101

Title: 2-{[(4-{[(2-Hy-droxy-phen-yl)(phen-yl)methyl-idene]amino}-phen-yl)imino](phen-yl)meth-yl}phenol.

Journal: Acta crystallographica. Section E, Structure reports online 20111201

Title: Domino reaction to functionalized 2-hydroxybenzophenones from electron-deficient chromones and 1,3-dicarbonyl compounds.

Journal: The Journal of organic chemistry 20111021

Title: Rearrangement of 2-aryloxybenzaldehydes to 2-hydroxybenzophenones by rhodium-catalyzed cleavage of aryloxy C-O bonds.

Journal: Angewandte Chemie (International ed. in English) 20110912

Title: Chiral phosphoric acid catalyzed enantioselective transfer hydrogenation of ortho-hydroxybenzophenone N-H ketimines and applications.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20110822

Title: A facile synthesis of highly functionalized 4-arylcoumarins via Kostanecki reactions mediated by DBU.

Journal: Molecules (Basel, Switzerland) 20110726

Title: Hexametallic manganese clusters with bulky derivatised salicylaldoximes.

Journal: Dalton transactions (Cambridge, England : 2003) 20110227

Title: A monohydrate pseudopolymorph of 3,4-dihydroxybenzophenone and the role of water in the crystal assembly of benzophenones.

Journal: Acta crystallographica. Section C, Crystal structure communications 20100901

Title: N,N'-Bis[(2-hydroxy-phen-yl)(phen-yl)methyl-idene]propane-1,2-diamine.

Journal: Acta crystallographica. Section E, Structure reports online 20100601

Title: 2,2'-[(Propane-1,3-diyldinitrilo)bis-(phenyl-methyl-idyne)]diphenol.

Journal: Acta crystallographica. Section E, Structure reports online 20100401

Title: DDQ oxidation of hydroxyisochromans and homologues.

Journal: Natural product research 20100301

Title: Solid-phase extraction followed by liquid chromatography-tandem mass spectrometry for the determination of hydroxylated benzophenone UV absorbers in environmental water samples.

Journal: Analytica chimica acta 20091110

Title: Miniaturized hollow fiber assisted liquid-phase microextraction and gas chromatography-mass spectrometry for determination of benzophenone and derivates in human urine sample.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090115

Title: Synthesis and spectral feature of benzophenone-substituted thiosemicarbazones and their Ni(II) and Cu(II) complexes.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20090101

Title: Reaction of diphenyldiazomethane with singlet oxygen studied by time-resolved IR spectroscopy.

Journal: The Journal of organic chemistry 20080919

Title: Simultaneous analysis of benzophenone sunscreen compounds in water sample by stir bar sorptive extraction with in situ derivatization and thermal desorption-gas chromatography-mass spectrometry.

Journal: Journal of chromatography. A 20080725

Title: Concentrations of the sunscreen agent benzophenone-3 in residents of the United States: National Health and Nutrition Examination Survey 2003--2004.

Journal: Environmental health perspectives 20080701

Title: Polymetallic clusters of iron(III) with derivatised salicylaldoximes.

Journal: Dalton transactions (Cambridge, England : 2003) 20080421

Title: Measurement of benzophenones in human urine samples by stir bar sorptive extraction and thermal desorption-gas chromatography-mass spectrometry.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20080101

Title: Spectroscopic, thermal and biological studies on some trivalent ruthenium and rhodium NS chelating thiosemicarbazone complexes.

Journal: Bioinorganic chemistry and applications 20070101

Title: Novel laser-induced luminescence resulting from benzophenone/O-propylated p-tert-butylcalix[4]arene complexes. A diffuse reflectance study.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20031001

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