Home Other Building Blocks 1206163-45-2
1206163-45-2,MFCD26960569
Catalog No.:AA008TKD

1206163-45-2 | Solcitinib

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98+%
in stock  
$16.00   $11.00
- +
5mg
98+%
in stock  
$39.00   $28.00
- +
10mg
98+%
in stock  
$60.00   $42.00
- +
50mg
98+%
in stock  
$169.00   $118.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA008TKD
Chemical Name:
Solcitinib
CAS Number:
1206163-45-2
Molecular Formula:
C22H23N5O2
Molecular Weight:
389.4503
MDL Number:
MFCD26960569
SMILES:
O=C(C1CC1)Nc1nn2c(n1)cccc2c1ccc(cc1)C(=O)N1CC(C1)(C)C
Properties
Computed Properties
 
Complexity:
648  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
4  
XLogP3:
2.8  

Literature

Title: Safety, tolerability, efficacy and pharmacodynamics of the selective JAK1 inhibitor GSK2586184 in patients with systemic lupus erythematosus.

Journal: Lupus 20161101

Title: Investigation of selective JAK1 inhibitor GSK2586184 for the treatment of psoriasis in a randomized placebo-controlled phase IIa study.

Journal: The British journal of dermatology 20160501

Title: Induction of corneal graft rejection by passive cell transfer.

Journal: Investigative ophthalmology 19760201

Title: Ludbrook VJ, et al. Investigation of selective JAK1 inhibitor GSK2586184 for the treatment of psoriasis in a randomized placebo-controlled phase IIa study. Br J Dermatol. 2016 May;174(5):985-95.

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SDS
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