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121324-31-0,MFCD05863929
Catalog No.:AA0076Y0

121324-31-0 | POV-PC

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1mg
≥98%
in stock  
$135.00   $94.00
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5mg
≥98%
in stock  
$598.00   $418.00
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10mg
≥98%
in stock  
$1,056.00   $739.00
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25mg
≥98%
in stock  
$2,305.00   $1,613.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0076Y0
Chemical Name:
POV-PC
CAS Number:
121324-31-0
Molecular Formula:
C29H56NO9P
Molecular Weight:
593.7300
MDL Number:
MFCD05863929
SMILES:
CCCCCCCCCCCCCCCC(=O)OC[C@@H](OC(=O)CCCC=O)COP(=O)(OCC[N+](C)(C)C)[O-]
Properties
Computed Properties
 
Complexity:
704  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
40  
Hydrogen Bond Acceptor Count:
9  
Rotatable Bond Count:
30  
XLogP3:
5.9  

Literature

Title: Inhibition of oxidized-phospholipid-induced vascular smooth muscle cell proliferation by resveratrol is associated with reducing Cx43 phosphorylation.

Journal: Journal of agricultural and food chemistry 20131106

Title: Uptake and protein targeting of fluorescent oxidized phospholipids in cultured RAW 264.7 macrophages.

Journal: Biochimica et biophysica acta 20120401

Title: Reductive metabolism increases the proinflammatory activity of aldehyde phospholipids.

Journal: Journal of lipid research 20111201

Title: Catalytic reduction of carbonyl groups in oxidized PAPC by Kvβ2 (AKR6).

Journal: Chemico-biological interactions 20110530

Title: Implication of lipoprotein associated phospholipase A2 activity in oxLDL uptake by macrophages.

Journal: Journal of lipid research 20100801

Title: Short-term stimulation of calcium-permeable transient receptor potential canonical 5-containing channels by oxidized phospholipids.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20100701

Title: Oxidation changes physical properties of phospholipid bilayers: fluorescence spectroscopy and molecular simulations.

Journal: Langmuir : the ACS journal of surfaces and colloids 20100504

Title: Oxidized phosphatidylcholine formation and action in oligodendrocytes.

Journal: Journal of neurochemistry 20090901

Title: Oxidized phospholipid species promote in vivo differential cx43 phosphorylation and vascular smooth muscle cell proliferation.

Journal: The American journal of pathology 20090801

Title: The role of the scavenger receptor CD36 in regulating mononuclear phagocyte trafficking to atherosclerotic lesions and vascular inflammation.

Journal: Cardiovascular research 20090701

Title: Oxidized phospholipids induce type VIII collagen expression and vascular smooth muscle cell migration.

Journal: Circulation research 20090313

Title: Autoantibodies to oxidized low density lipoprotein in relation with coronary artery disease.

Journal: Human antibodies 20090101

Title: Kruppel-like factor 4, Elk-1, and histone deacetylases cooperatively suppress smooth muscle cell differentiation markers in response to oxidized phospholipids.

Journal: American journal of physiology. Cell physiology 20081101

Title: Oxidized phospholipids induce anergy in human peripheral blood T cells.

Journal: European journal of immunology 20080301

Title: Oxidized phosphatidylcholine is a marker for neuroinflammation in multiple sclerosis brain.

Journal: Journal of neuroscience research 20070401

Title: Import and fate of fluorescent analogs of oxidized phospholipids in vascular smooth muscle cells.

Journal: Journal of lipid research 20070301

Title: Oxidized phospholipid: POVPC binds to platelet-activating-factor receptor on human macrophages. Implications in atherosclerosis.

Journal: Atherosclerosis 20061001

Title: Activation of CD36 inhibits and induces regression of inflammatory corneal neovascularization.

Journal: Investigative ophthalmology & visual science 20061001

Title: The oxidized phospholipids POVPC and PGPC inhibit growth and induce apoptosis in vascular smooth muscle cells.

Journal: Biochimica et biophysica acta 20060901

Title: Specific monocyte adhesion to endothelial cells induced by oxidized phospholipids involves activation of cPLA2 and lipoxygenase.

Journal: Journal of lipid research 20060501

Title: Role of endothelial nitric oxide synthase in the regulation of SREBP activation by oxidized phospholipids.

Journal: Circulation research 20060331

Title: Identification of prostaglandin E2 receptor subtype 2 as a receptor activated by OxPAPC.

Journal: Circulation research 20060317

Title: A rancid culprit in vascular inflammation acts on the prostaglandin receptor EP2.

Journal: Circulation research 20060317

Title: Oxidized phospatidylcholine but not native phosphatidylcholine inhibits inducible nitric oxide synthase in RAW 264.7 macrophages.

Journal: Life sciences 20060227

Title: Release of free F2-isoprostanes from esterified phospholipids is catalyzed by intracellular and plasma platelet-activating factor acetylhydrolases.

Journal: The Journal of biological chemistry 20060224

Title: Aldose reductase-catalyzed reduction of aldehyde phospholipids.

Journal: The Journal of biological chemistry 20041217

Title: Role for sterol regulatory element-binding protein in activation of endothelial cells by phospholipid oxidation products.

Journal: Circulation research 20041015

Title: Rapid formation of 4-hydroxy-2-nonenal, malondialdehyde, and phosphatidylcholine aldehyde from phospholipid hydroperoxide by hemoproteins.

Journal: Free radical biology & medicine 20040415

Title: Oxidized phospholipid-induced endothelial cell/monocyte interaction is mediated by a cAMP-dependent R-Ras/PI3-kinase pathway.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20030801

Title: CTP:phosphocholine cytidylyltransferase and protein kinase C recognize different physical features of membranes: differential responses to an oxidized phosphatidylcholine.

Journal: Biochimica et biophysica acta 20020819

Title: Hydroxy alkenal phospholipids regulate inflammatory functions of endothelial cells.

Journal: Vascular pharmacology 20020401

Title: Correlation of antiphospholipid antibody recognition with the structure of synthetic oxidized phospholipids. Importance of Schiff base formation and aldol condensation.

Journal: The Journal of biological chemistry 20020301

Title: Oxidized membrane vesicles and blebs from apoptotic cells contain biologically active oxidized phospholipids that induce monocyte-endothelial interactions.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20020101

Title: Core aldehydes of alkyl glycerophosphocholines in atheroma induce platelet aggregation and inhibit endothelium-dependent arterial relaxation.

Journal: Journal of lipid research 20020101

Title: Scavenger receptor class B type I as a receptor for oxidized low density lipoprotein.

Journal: Journal of lipid research 20010901

Title: A cell-free assay for detecting HDL that is dysfunctional in preventing the formation of or inactivating oxidized phospholipids.

Journal: Journal of lipid research 20010801

Title: Involvement of aldose reductase in the metabolism of atherogenic aldehydes.

Journal: Chemico-biological interactions 20010130

Title: Induction of heme oxygenase-1 expression in macrophages by diesel exhaust particle chemicals and quinones via the antioxidant-responsive element.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20000915

Title: Natural antibodies with the T15 idiotype may act in atherosclerosis, apoptotic clearance, and protective immunity.

Journal: The Journal of clinical investigation 20000615

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