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1228675-18-0,MFCD17480504
Catalog No.:AA003AT4

1228675-18-0 | tert-Butyl 2,5-diazabicyclo[4.1.0]heptane-2-carboxylate

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100mg
98%
in stock  
$41.00   $29.00
- +
250mg
98%
in stock  
$72.00   $50.00
- +
1g
98%
in stock  
$231.00   $162.00
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5g
95%
in stock  
$1,065.00   $746.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003AT4
Chemical Name:
tert-Butyl 2,5-diazabicyclo[4.1.0]heptane-2-carboxylate
CAS Number:
1228675-18-0
Molecular Formula:
C10H18N2O2
Molecular Weight:
198.2621
MDL Number:
MFCD17480504
SMILES:
O=C(N1CCNC2C1C2)OC(C)(C)C
Properties
Computed Properties
 
Complexity:
247  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
Undefined Atom Stereocenter Count:
2  
XLogP3:
0.7  

Downstream Synthesis Route
1228675-18-0    1403676-74-3   
tert-butyl5-((1s,4s)-4-((2-fluoro-4-(methylsulfonyl)phenoxy)methyl)cyclohexyl)-2,5-diazabicyclo4.1.0heptane-2-carboxylate 
 
tert-butyl5-((1r,4r)-4-((2-fluoro-4-(methylsulfonyl)phenoxy)methyl)cyclohexyl)-2,5-diazabicyclo4.1.0heptane-2-carboxylate 

[1]CurrentPatentAssignee:PFIZERINC-WO2012/145361,2012,A1Locationinpatent:Page/Pagecolumn200

32315-10-9    1228675-18-0   
tert-butyl5-(chlorocarbonyl)-2,5-diazabicyclo4.1.0heptane-2-carboxylate 

[1]Zeng,Qingbei;Wang,Jiabing;Cheng,Ziqiang;Chen,Kan;Johnström,Peter;Varnäs,Katarina;Li,DavidYunzhi;Yang,ZhenFan;Zhang,Xiaolin[JournalofMedicinalChemistry,2015,vol.58,#20,p.8200-8215]

1228675-18-0   
4-(3-chloro-2-fluorophenylamino)-7-methoxyquinazolin-6-yl5-methyl-2,5-diazabicyclo4.1.0heptane-2-carboxylatehydrochloride 

[1]Zeng,Qingbei;Wang,Jiabing;Cheng,Ziqiang;Chen,Kan;Johnström,Peter;Varnäs,Katarina;Li,DavidYunzhi;Yang,ZhenFan;Zhang,Xiaolin[JournalofMedicinalChemistry,2015,vol.58,#20,p.8200-8215]

1228675-18-0   
2-tert-butyl5-(4-(3-chloro-2-fluorophenylamino)-7-methoxyquinazolin-6-yl)2,5-diazabicyclo4.1.0heptane-2,5-dicarboxylate 

[1]Zeng,Qingbei;Wang,Jiabing;Cheng,Ziqiang;Chen,Kan;Johnström,Peter;Varnäs,Katarina;Li,DavidYunzhi;Yang,ZhenFan;Zhang,Xiaolin[JournalofMedicinalChemistry,2015,vol.58,#20,p.8200-8215]

1228675-18-0   
4-(3-chloro-2-fluorophenylamino)-7-methoxyquinazolin-6-yl2,5-diazabicyclo4.1.0heptane-2-carboxylate 

[1]Zeng,Qingbei;Wang,Jiabing;Cheng,Ziqiang;Chen,Kan;Johnström,Peter;Varnäs,Katarina;Li,DavidYunzhi;Yang,ZhenFan;Zhang,Xiaolin[JournalofMedicinalChemistry,2015,vol.58,#20,p.8200-8215]

Literature
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Tags:1228675-18-0 Molecular Formula|1228675-18-0 MDL|1228675-18-0 SMILES|1228675-18-0 tert-Butyl 2,5-diazabicyclo[4.1.0]heptane-2-carboxylate