Title: Ceramide modulates pre-mRNA splicing to restore the expression of wild-type tumor suppressor p53 in deletion-mutant cancer cells.
Journal: Biochimica et biophysica acta 20141101
Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Journal: Bioorganic & medicinal chemistry 20121115
Title: Sphingomyelinase-induced adhesion of eryptotic erythrocytes to endothelial cells.
Journal: American journal of physiology. Cell physiology 20121101
Title: A shift in sphingolipid composition from C24 to C16 increases susceptibility to apoptosis in HeLa cells.
Journal: Biochimica et biophysica acta 20120701
Title: C6-ceramide and targeted inhibition of acid ceramidase induce synergistic decreases in breast cancer cell growth.
Journal: Breast cancer research and treatment 20120601
Title: Increasing ceramides sensitizes genistein-induced melanoma cell apoptosis and growth inhibition.
Journal: Biochemical and biophysical research communications 20120511
Title: Relevance of the salvage pathway to N-hexanoylsphingosine metabolic downregulation in human neurotumor cells: implications for apoptosis.
Journal: Drug metabolism letters 20120301
Title: Regulation of alternative splicing within the supraspliceosome.
Journal: Journal of structural biology 20120101
Title: C(6)-ceramide enhances phagocytic activity of Kupffer cells through the production of endogenous ceramides.
Journal: Molecules and cells 20111031
Title: P-glycoprotein antagonists confer synergistic sensitivity to short-chain ceramide in human multidrug-resistant cancer cells.
Journal: Experimental cell research 20110715
Title: Ceramide inhibits Kv currents and contributes to TP-receptor-induced vasoconstriction in rat and human pulmonary arteries.
Journal: American journal of physiology. Cell physiology 20110701
Title: ABCB1 protects kidney proximal tubule cells against cadmium-induced apoptosis: roles of cadmium and ceramide transport.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20110601
Title: Nanoliposomal ceramide prevents in vivo growth of hepatocellular carcinoma.
Journal: Gut 20110501
Title: Mitochondrially targeted ceramides preferentially promote autophagy, retard cell growth, and induce apoptosis.
Journal: Journal of lipid research 20110201
Title: Lipid component quantitation by thin layer chromatography.
Journal: Methods in molecular biology (Clifton, N.J.) 20110101
Title: Coupling in vitro and in vivo paradigm reveals a dose dependent inhibition of angiogenesis followed by initiation of autophagy by C6-ceramide.
Journal: International journal of biological sciences 20110101
Title: Peripheral neuropathy in the Twitcher mouse involves the activation of axonal caspase 3.
Journal: ASN neuro 20110101
Title: C6 ceramide potentiates curcumin-induced cell death and apoptosis in melanoma cell lines in vitro.
Journal: Cancer chemotherapy and pharmacology 20101001
Title: Metabolism of short-chain ceramide by human cancer cells--implications for therapeutic approaches.
Journal: Biochemical pharmacology 20100801
Title: Ceramide modulates HERG potassium channel gating by translocation into lipid rafts.
Journal: American journal of physiology. Cell physiology 20100701
Title: Cell-permeable ceramides act as novel regulators of U937 cell-cell adhesion mediated by CD29, CD98, and CD147.
Journal: Immunobiology 20100401
Title: Phospholipase D modulation by ceramide in senescence.
Journal: Molecular and cellular biochemistry 20100401
Title: Liposomes for drug delivery to mitochondria.
Journal: Methods in molecular biology (Clifton, N.J.) 20100101
Title: Long-chain ceramide produced in response to N-hexanoylsphingosine does not induce apoptosis in CHP-100 cells.
Journal: Lipids 20091101
Title: Ceramides: branched alkyl chains in the sphingolipid siblings of diacylglycerol improve biological potency.
Journal: Bioorganic & medicinal chemistry 20090215
Title: A role for ceramide in driving cancer cell resistance to doxorubicin.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080701
Title: Apoptotic effects of dietary and synthetic sphingolipids in androgen-independent (PC-3) prostate cancer cells.
Journal: Lipids 20080201
Title: C(6)-ceramide inhibited Na(+) currents by intracellular Ca(2+) release in rat myoblasts.
Journal: Journal of cellular physiology 20071001
Title: Mitochondrial protein phosphatase 2A regulates cell death induced by simulated ischemia in kidney NRK-52E cells.
Journal: Cell cycle (Georgetown, Tex.) 20071001
Title: Ceramide-induced cell death in lens epithelial cells.
Journal: Molecular vision 20070910
Title: Cadmium-induced ceramide formation triggers calpain-dependent apoptosis in cultured kidney proximal tubule cells.
Journal: American journal of physiology. Cell physiology 20070901
Title: Nuclear localization of endogenous RGK proteins and modulation of cell shape remodeling by regulated nuclear transport.
Journal: Traffic (Copenhagen, Denmark) 20070901
Title: The functional effects of acid ceramidase overexpression in prostate cancer progression and resistance to chemotherapy.
Journal: Cancer biology & therapy 20070901
Title: De novo ceramide biosynthesis is associated with resveratrol-induced inhibition of ornithine decarboxylase activity.
Journal: Biochemical pharmacology 20070715
Title: Ceramide recruits and activates protein kinase C zeta (PKC zeta) within structured membrane microdomains.
Journal: The Journal of biological chemistry 20070427
Title: Solid-phase synthesis of a combinatorial library of dihydroceramide analogues and its activity in human alveolar epithelial cells.
Journal: Bioorganic & medicinal chemistry 20070101
Title: Sphingosine 1-phosphate: a novel stimulator of aldosterone secretion.
Journal: Journal of lipid research 20060601
Title: Colocalization of oxidized low-density lipoprotein, caspase-3, cyclooxygenase-2, and macrophage migration inhibitory factor in arteriosclerotic human carotid arteries.
Journal: Cell and tissue research 20051201
Title: Ultraviolet A-induced signaling involves a ceramide-mediated autocrine loop leading to ceramide de novo synthesis.
Journal: The Journal of investigative dermatology 20050901
Title: Resistance to TRAIL is associated with defects in ceramide signaling that can be overcome by exogenous C6-ceramide without requiring down-regulation of cellular FLICE inhibitory protein.
Journal: Molecular cancer therapeutics 20050901
Title: Regulatory roles of cell surface sialylation in susceptibility to sphingomyelinase in human diffuse large B cell lymphoma.
Journal: International journal of oncology 20050701
Title: Molecular associations and surface-active properties of short- and long-N-acyl chain ceramides.
Journal: Biochimica et biophysica acta 20050601
Title: Ceramide alters endothelial cell permeability by a nonapoptotic mechanism.
Journal: British journal of pharmacology 20050501
Title: Systemic delivery of liposomal short-chain ceramide limits solid tumor growth in murine models of breast adenocarcinoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20050501
Title: Activation of serine/threonine protein phosphatase-1 is required for ceramide-induced survival of sympathetic neurons.
Journal: The Biochemical journal 20050201
Title: Potentiation of ceramide-induced apoptosis by p27kip1 overexpression.
Journal: Archives of pharmacal research 20050101
Title: Differential expression of proteins in response to ceramide-mediated stress signal in colon cancer cells by 2-D gel electrophoresis and MALDI-TOF-MS.
Journal: Journal of proteome research 20050101
Title: TNFalpha reduces the expression of peroxisome proliferator-activated receptor gamma (PPARgamma) via the production of ceramide and activation of atypical PKC.
Journal: Diabetes research and clinical practice 20041201
Title: Involvement of growth differentiation factor-15/macrophage inhibitory cytokine-1 (GDF-15/MIC-1) in oxLDL-induced apoptosis of human macrophages in vitro and in arteriosclerotic lesions.
Journal: Cell and tissue research 20041101
Title: Synergistic effect of interleukin (IL)-1alpha and ceramide analogue on the production of IL-6, IL-8, and macrophage colony-stimulating factor by endometrial stromal cells.
Journal: Fertility and sterility 20041001
Title: Ceramide synthesis correlates with the posttranscriptional regulation of the sterol-regulatory element-binding protein.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20040501
Title: Plasma membrane aquaporin activity can affect the rate of apoptosis but is inhibited after apoptotic volume decrease.
Journal: American journal of physiology. Cell physiology 20040401
Title: Sphingomyelin synthase as a potential target for D609-induced apoptosis in U937 human monocytic leukemia cells.
Journal: Experimental cell research 20040115
Title: Nicotine-induced neuroprotection against N-methyl-D-aspartic acid or beta-amyloid peptide occur through independent mechanisms distinguished by pro-inflammatory cytokines.
Journal: Journal of neurochemistry 20031201
Title: Mitochondrial cytochrome c release mediates ceramide-induced activator protein 2 activation and gene expression in keratinocytes.
Journal: The Journal of biological chemistry 20031128
Title: Liposomal delivery enhances short-chain ceramide-induced apoptosis of breast cancer cells.
Journal: The Journal of pharmacology and experimental therapeutics 20031101
Title: Ceramide accumulation precedes caspase-3 activation during apoptosis of A549 human lung adenocarcinoma cells.
Journal: American journal of physiology. Lung cellular and molecular physiology 20030601
Title: Mechanisms involved in exogenous C2- and C6-ceramide-induced cancer cell toxicity.
Journal: Biochemical pharmacology 20030515
Title: Modulation of transforming growth factor-beta (TGF-beta) signaling by endogenous sphingolipid mediators.
Journal: The Journal of biological chemistry 20030314
Title: Differential roles of 2, 6, and 8 carbon ceramides on the modulation of gap junctional communication and apoptosis during carcinogenesis.
Journal: Cancer letters 20030227
Title: Anti-apoptotic role of phospholipase D isozymes in the glutamate-induced cell death.
Journal: Experimental & molecular medicine 20030227
Title: Activation of the Drosophila MLK by ceramide reveals TNF-alpha and ceramide as agonists of mammalian MLK3.
Journal: Molecular cell 20021201
Title: Modulation of CYP3A4 expression by ceramide in human colon carcinoma HT-29 cells.
Journal: Biochemical and biophysical research communications 20021115
Title: Synthetic ceramides induce growth arrest or apoptosis by altering cellular redox status.
Journal: Archives of biochemistry and biophysics 20021101
Title: Dual effect of ceramide on human endothelial cells: induction of oxidative stress and transcriptional upregulation of endothelial nitric oxide synthase.
Journal: Circulation 20021022
Title: Influence of ceramide metabolism on P-glycoprotein function in immature acute myeloid leukemia KG1a cells.
Journal: Molecular pharmacology 20020801
Title: Telomerase positive human diploid fibroblasts are resistant to replicative senescence but not premature senescence induced by chemical reagents.
Journal: Biogerontology 20020101
Title: Ceramide-mediated apoptosis in lung epithelial cells is regulated by glutathione.
Journal: American journal of respiratory cell and molecular biology 20011201
Title: Synergistic effect of interleukin-1alpha and ceramide analogue on production of prostaglandin E2 and F2alpha by endometrial stromal cells.
Journal: American journal of reproductive immunology (New York, N.Y. : 1989) 20011201
Title: [Rapid induction of senescence-like changes in human umbilic vein endothelial cells(HUVECs) by C6 ceramide].
Journal: Shi yan sheng wu xue bao 20011201
Title: Ceramide accelerates dephosphorylation of extracellular signal-regulated kinase 1/2 to decrease prostaglandin D(2) production in RBL-2H3 cells.
Journal: Archives of biochemistry and biophysics 20011115
Title: Ceramide modulates nicotinic receptor-dependent Ca(2+) signaling in rat chromaffin cells.
Journal: Journal of neuroscience research 20011115
Title: Ceramide inhibits the outward potassium current in rat pinealocytes.
Journal: Journal of neurochemistry 20011001
Title: Ceramide inhibits axonal growth and nerve growth factor uptake without compromising the viability of sympathetic neurons.
Journal: The Journal of biological chemistry 20010928
Title: Bax-dependent apoptosis induced by ceramide in HL-60 cells.
Journal: FEBS letters 20010914
Title: Molecular mechanisms of ceramide-mediated telomerase inhibition in the A549 human lung adenocarcinoma cell line.
Journal: The Journal of biological chemistry 20010831
Title: Role of ceramide in mediating the inhibition of telomerase activity in A549 human lung adenocarcinoma cells.
Journal: The Journal of biological chemistry 20010706
Title: Fumonisin-induced tumor necrosis factor-alpha expression in a porcine kidney cell line is independent of sphingoid base accumulation induced by ceramide synthase inhibition.
Journal: Toxicology and applied pharmacology 20010701
Title: Inhibitory actions of ceramide upon PKC-epsilon/ERK interactions.
Journal: American journal of physiology. Cell physiology 20010601
Title: Psychosine is as potent an inducer of cell death as C6-ceramide in cultured fibroblasts and in MOCH-1 cells.
Journal: Neurochemical research 20010601
Title: Induction of apoptotic cell death and prevention of tumor growth by ceramide analogues in metastatic human colon cancer.
Journal: Cancer research 20010201
Title: Nitric oxide inhibits apoptosis via AP-1-dependent CD95L transactivation.
Journal: Cancer research 20000501
Title: Induction of the manganese superoxide dismutase gene by sphingomyelinase and ceramide.
Journal: Journal of neurochemistry 19990801
Title: Ceramide-induced apoptosis is mediated by caspase activation independently from retinoblastoma protein post-translational modification.
Journal: Biochemical and biophysical research communications 19980224