[1]CurrentPatentAssignee:EXELIXISINC-WO2010/118208,2010,A1Locationinpatent:Page/Pagecolumn250-251
[1]Takeuchi,CraigS.;Kim,ByungGyu;Blazey,CharlesM.;Ma,Sunghoon;Johnson,HenryW.B.;Anand,NeelK.;Arcalas,Arlyn;Baik,TaeGon;Buhr,ChrisA.;Cannoy,Jonah;Epshteyn,Sergey;Joshi,Anagha;Lara,Katherine;Lee,MatthewS.;Wang,Longcheng;Leahy,JamesW.;Nuss,JohnM.;Aay,Naing;Aoyama,Ron;Foster,Paul;Lee,Jae;Lehoux,Isabelle;Munagala,Narsimha;Plonowski,Arthur;Rajan,Sharmila;Woolfrey,John;Yamaguchi,Kyoko;Lamb,Peter;Miller,Nicole[JournalofMedicinalChemistry,2013,vol.56,#6,p.2218-2234]
[2]Naganathan,Sriram;Andersen,DeniseL.;Andersen,NeilG.;Lau,Stephen;Lohse,Anders;Sorensen,MadsDetlef[OrganicProcessResearchandDevelopment,2015,vol.19,#7,p.721-734]
[1]Takeuchi,CraigS.;Kim,ByungGyu;Blazey,CharlesM.;Ma,Sunghoon;Johnson,HenryW.B.;Anand,NeelK.;Arcalas,Arlyn;Baik,TaeGon;Buhr,ChrisA.;Cannoy,Jonah;Epshteyn,Sergey;Joshi,Anagha;Lara,Katherine;Lee,MatthewS.;Wang,Longcheng;Leahy,JamesW.;Nuss,JohnM.;Aay,Naing;Aoyama,Ron;Foster,Paul;Lee,Jae;Lehoux,Isabelle;Munagala,Narsimha;Plonowski,Arthur;Rajan,Sharmila;Woolfrey,John;Yamaguchi,Kyoko;Lamb,Peter;Miller,Nicole[JournalofMedicinalChemistry,2013,vol.56,#6,p.2218-2234]
[1]Takeuchi,CraigS.;Kim,ByungGyu;Blazey,CharlesM.;Ma,Sunghoon;Johnson,HenryW.B.;Anand,NeelK.;Arcalas,Arlyn;Baik,TaeGon;Buhr,ChrisA.;Cannoy,Jonah;Epshteyn,Sergey;Joshi,Anagha;Lara,Katherine;Lee,MatthewS.;Wang,Longcheng;Leahy,JamesW.;Nuss,JohnM.;Aay,Naing;Aoyama,Ron;Foster,Paul;Lee,Jae;Lehoux,Isabelle;Munagala,Narsimha;Plonowski,Arthur;Rajan,Sharmila;Woolfrey,John;Yamaguchi,Kyoko;Lamb,Peter;Miller,Nicole[JournalofMedicinalChemistry,2013,vol.56,#6,p.2218-2234]
[2]Naganathan,Sriram;Andersen,DeniseL.;Andersen,NeilG.;Lau,Stephen;Lohse,Anders;Sorensen,MadsDetlef[OrganicProcessResearchandDevelopment,2015,vol.19,#7,p.721-734]
[1]Takeuchi,CraigS.;Kim,ByungGyu;Blazey,CharlesM.;Ma,Sunghoon;Johnson,HenryW.B.;Anand,NeelK.;Arcalas,Arlyn;Baik,TaeGon;Buhr,ChrisA.;Cannoy,Jonah;Epshteyn,Sergey;Joshi,Anagha;Lara,Katherine;Lee,MatthewS.;Wang,Longcheng;Leahy,JamesW.;Nuss,JohnM.;Aay,Naing;Aoyama,Ron;Foster,Paul;Lee,Jae;Lehoux,Isabelle;Munagala,Narsimha;Plonowski,Arthur;Rajan,Sharmila;Woolfrey,John;Yamaguchi,Kyoko;Lamb,Peter;Miller,Nicole[JournalofMedicinalChemistry,2013,vol.56,#6,p.2218-2234]
[2]Naganathan,Sriram;Andersen,DeniseL.;Andersen,NeilG.;Lau,Stephen;Lohse,Anders;Sorensen,MadsDetlef[OrganicProcessResearchandDevelopment,2015,vol.19,#7,p.721-734]
Title: Discovery of a novel class of highly potent, selective, ATP-competitive, and orally bioavailable inhibitors of the mammalian target of rapamycin (mTOR).
Journal: Journal of medicinal chemistry 20130328
Title: Takeuchi CS, et al. Discovery of a novel class of highly potent, selective, ATP-competitive, and orally bioavailable inhibitors of the mammalian target of rapamycin (mTOR). J Med Chem. 2013 Mar 28;56(6):2218-34.
Title: Zhu YR, et al. The anti-cancer activity of the mTORC1/2 dual inhibitor XL388 in preclinical osteosarcoma models. Oncotarget. 2016 Aug 2;7(31):49527-49538.
