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Home Other Building Blocks 1264191-73-2
1264191-73-2,MFCD22741503
Catalog No.:AA009CCT

1264191-73-2 | VTP-27999 Hydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
98%
1 week  
$255.00   $179.00
- +
10mg
98%
1 week  
$368.00   $258.00
- +
50mg
98%
1 week  
$1,066.00   $747.00
- +
100mg
98%
1 week  
$1,670.00   $1,169.00
- +
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA009CCT
Chemical Name:
VTP-27999 Hydrochloride
CAS Number:
1264191-73-2
Molecular Formula:
C26H42Cl2N4O5
Molecular Weight:
561.5415
MDL Number:
MFCD22741503
SMILES:
CN[C@@H](C[C@H]1CCCOC1)CNC(=O)N1CCC[C@H](C1)[C@H](c1cccc(c1)Cl)OCCNC(=O)OC.Cl
Properties
Computed Properties
 
Complexity:
672  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
4  
Heavy Atom Count:
37  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
12  

Literature

Title: Lanqi Jia et al. Discovery of VTP-27999, an Alkyl Amine Renin Inhibitor with Potential for Clinical Utility ACS Med. Chem. Lett., 2011, 2 (10), pp 747-751

Title: New renin inhibitor VTP-27999 alters renin immunoreactivity and does not unfold prorenin. Hypertension. 2013 May;61(5):1075-1082.

Title: Ishchenko A, et al. Structure-based design technology contour and its application to the design of Renin inhibitors.J Chem Inf Model. 2012 Aug 27;52(8):2089-97. Epub 2012 Jul 25.

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SDS
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Tags:1264191-73-2 Molecular Formula|1264191-73-2 MDL|1264191-73-2 SMILES|1264191-73-2 VTP-27999 Hydrochloride