Home Pyridines 126454-22-6
126454-22-6,MFCD27966190
Catalog No.:AA000SQG

126454-22-6 | 2,3'-Bipyridine, 1,2,3,6-tetrahydro-, (2R)-

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  • Technical Information
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Technical Information
Catalog Number:
AA000SQG
Chemical Name:
2,3'-Bipyridine, 1,2,3,6-tetrahydro-, (2R)-
CAS Number:
126454-22-6
Molecular Formula:
C10H12N2
Molecular Weight:
160.2157
MDL Number:
MFCD27966190
SMILES:
C1=CC[C@@H](NC1)c1cccnc1
Properties
Computed Properties
 
Complexity:
165  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
0.9  

Literature

Title: Jothi L. Nallasivam, et al. Synthetic modifications of bifunctional homoallylamines: Synthesis of 2-arylpiperidines, (R)-anatabine and (R)-anabasine. An International Journal for Rapid Communication of Synthetic Organic Chemistry. Volume 49, 2019-Issue 21: 2815-2822.

Title: Paris D, et al. Anatabine lowers Alzheimer's Aβ production in vitro and in vivo. Eur J Pharmacol. 2011 Nov 30;670(2-3):384-91.

Title: Xing H, et al. A Pharmacological Comparison of Two Isomeric Nicotinic Receptor Agonists: The Marine Toxin Isoanatabine and the Tobacco Alkaloid Anatabine. Mar Drugs. 2020 Feb 11;18(2). pii: E106.

Title: eo EJ, et al. Phytochemicals as inhibitors of NF-κB for treatment of Alzheimer's disease. Pharmacol Res. 2018 Mar;129:262-273.

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SDS
Tags:126454-22-6 Molecular Formula|126454-22-6 MDL|126454-22-6 SMILES|126454-22-6 2,3'-Bipyridine, 1,2,3,6-tetrahydro-, (2R)-