Title: The VEP1 gene (At4g24220) encodes a short-chain dehydrogenase/reductase with 3-oxo-Delta4,5-steroid 5beta-reductase activity in Arabidopsis thaliana L.
Journal: Biochimie 20090401
Title: Metabolism of neuroactive steroids in day-old chick brain.
Journal: Journal of neurochemistry 20090401
Title: Measurement of ring A-reduced progesterone metabolites by enzyme-linked immunoassay with colorimetric detection: baseline levels of six metabolites, including pregnanolone, in male rat plasma.
Journal: Analytical chemistry 20090201
Title: Insights into ligand-elicited activation of human constitutive androstane receptor based on novel agonists and three-dimensional quantitative structure-activity relationship.
Journal: Journal of medicinal chemistry 20081127
Title: Antinociceptive profile of ring A-reduced progesterone metabolites in the formalin test.
Journal: Pain 20080831
Title: The crystal structure of human Delta4-3-ketosteroid 5beta-reductase defines the functional role of the residues of the catalytic tetrad in the steroid double bond reduction mechanism.
Journal: Biochemistry 20080812
Title: The crystal structure of progesterone 5beta-reductase from Digitalis lanata defines a novel class of short chain dehydrogenases/reductases.
Journal: The Journal of biological chemistry 20080620
Title: Regulation of vascular tone during pregnancy: a novel role for the pregnane X receptor.
Journal: Hypertension (Dallas, Tex. : 1979) 20070201
Title: In silico prediction of pregnane X receptor activators by machine learning approaches.
Journal: Molecular pharmacology 20070101
Title: Circulating levels of pregnanolone isomers during the third trimester of human pregnancy.
Journal: The Journal of steroid biochemistry and molecular biology 20070101
Title: Influence of mirtazapine on plasma concentrations of neuroactive steroids in major depression and on 3alpha-hydroxysteroid dehydrogenase activity.
Journal: Molecular psychiatry 20060301
Title: Crystallization and preliminary crystallographic analysis of selenomethionine-labelled progesterone 5beta-reductase from Digitalis lanata Ehrh.
Journal: Acta crystallographica. Section F, Structural biology and crystallization communications 20060301
Title: Molecular cloning and heterologous expression of progesterone 5beta-reductase from Digitalis lanata Ehrh.
Journal: Phytochemistry 20060201
Title: 3alpha-reduced neuroactive steroids and their precursors during pregnancy and the postpartum period.
Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20051101
Title: 5 Beta-dihydroprogesterone and steroid 5 beta-reductase decrease in association with human parturition at term.
Journal: Molecular human reproduction 20050701
Title: Plasma concentrations of neuroactive steroids before and after electroconvulsive therapy in major depression.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050601
Title: Metabolites of progesterone and the pregnane X receptor: a novel pathway regulating uterine contractility in pregnancy?
Journal: American journal of obstetrics and gynecology 20050401
Title: Oestrogen and testosterone modulate the firing activity of dorsal raphe nucleus serotonergic neurones in both male and female rats.
Journal: Journal of neuroendocrinology 20050301
Title: A PXR reporter gene assay in a stable cell culture system: CYP3A4 and CYP2B6 induction by pesticides.
Journal: Biochemical pharmacology 20041215
Title: Insight into the mechanism of action of neuroactive steroids.
Journal: Molecular pharmacology 20040701
Title: Modulation of the firing activity of female dorsal raphe nucleus serotonergic neurons by neuroactive steroids.
Journal: The Journal of endocrinology 20040701
Title: Identification of 3beta,5beta-tetrahydroprogesterone, a progesterone metabolite, and its stimulatory action on preoptic neurons in the avian brain.
Journal: Brain research 20040508
Title: Molecular determinants of steroid inhibition for the mouse constitutive androstane receptor.
Journal: Journal of medicinal chemistry 20031023
Title: Specificity of human alcohol dehydrogenase 1C*2 (gamma2gamma2) for steroids and simulation of the uncompetitive inhibition of ethanol metabolism.
Journal: Chemico-biological interactions 20030201
Title: The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism.
Journal: Endocrine reviews 20021001
Title: Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin.
Journal: The Journal of biological chemistry 20010504
Title: Developmental changes in progesterone biosynthesis and metabolism in the quail brain.
Journal: Brain research 20010413
Title: Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands.
Journal: The Journal of biological chemistry 20000519
Title: The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution.
Journal: Molecular endocrinology (Baltimore, Md.) 20000101
