Home Amines 1281816-04-3
1281816-04-3,MFCD31715410
Catalog No.:AA003APP

1281816-04-3 | Maytansine, N2'-[3-[[1-[[trans-4-[[[(5S)-5-amino-5-carboxypentyl]amino]carbonyl]cyclohexyl]methyl]-2,5-dioxo-3-pyrrolidinyl]thio]-1-oxopropyl]-N2'-deacetyl-

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
1 week  
$388.00   $272.00
- +
5mg
1 week  
$847.00   $593.00
- +
10mg
1 week  
$1,197.00   $838.00
- +
25mg
1 week  
$1,749.00   $1,224.00
- +
  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003APP
Chemical Name:
Maytansine, N2'-[3-[[1-[[trans-4-[[[(5S)-5-amino-5-carboxypentyl]amino]carbonyl]cyclohexyl]methyl]-2,5-dioxo-3-pyrrolidinyl]thio]-1-oxopropyl]-N2'-deacetyl-
CAS Number:
1281816-04-3
Molecular Formula:
C53H75ClN6O15S
Molecular Weight:
1103.7118
MDL Number:
MFCD31715410
SMILES:
CO[C@@H]1C=CC=C(C)Cc2cc(OC)c(c(c2)N(C(=O)C[C@@H]([C@]2([C@@H]([C@@H]([C@@H]3C[C@@]1(O)NC(=O)O3)C)O2)C)OC(=O)[C@@H](N(C(=O)CCSC1CC(=O)N(C1=O)CC1CCC(CC1)C(=O)NCCCC[C@@H](C(=O)O)N)C)C)C)Cl
Properties
Computed Properties
 
Complexity:
2200  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
9  
Defined Bond Stereocenter Count:
2  
Heavy Atom Count:
76  
Hydrogen Bond Acceptor Count:
17  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
19  
Undefined Atom Stereocenter Count:
1  
XLogP3:
-0.2  

Literature

Title: Ogitani Y, et al. Bystander killing effect of DS-8201a, a novel anti-human epidermal growth factor receptor 2 antibody-drug conjugate, in tumors with human epidermal growth factor receptor 2 heterogeneity. Cancer Sci. 2016 Jul;107(7):1039-46.

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SDS
Tags:1281816-04-3 Molecular Formula|1281816-04-3 MDL|1281816-04-3 SMILES|1281816-04-3 Maytansine, N2'-[3-[[1-[[trans-4-[[[(5S)-5-amino-5-carboxypentyl]amino]carbonyl]cyclohexyl]methyl]-2,5-dioxo-3-pyrrolidinyl]thio]-1-oxopropyl]-N2'-deacetyl-