[1]ChemicalandPharmaceuticalBulletin,1996,vol.44,p.734-745
[1]ChemicalandPharmaceuticalBulletin,1996,vol.44,p.734-745
[1]ChemicalandPharmaceuticalBulletin,1996,vol.44,p.734-745
[1]BioorganicandMedicinalChemistry,2004,vol.12,p.5661-5675
[2]Patent:US6420426,2002,B1
[1]BioorganicandMedicinalChemistry,2004,vol.12,p.5661-5675
Title: In vitro metabolism of CP-122,721 ((2S,3S)-2-phenyl-3-[(5-trifluoromethoxy-2-methoxy)benzylamino]piperidine), a non-peptide antagonist of the substance P receptor.
Journal: Drug metabolism and pharmacokinetics 20071001
Title: Metabolism, pharmacokinetics, and excretion of the substance P receptor antagonist CP-122,721 in humans: structural characterization of the novel major circulating metabolite 5-trifluoromethoxy salicylic acid by high-performance liquid chromatography-tandem mass spectrometry and NMR spectroscopy.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20070601
Title: Metabolism and excretion of CP-122,721, a non-peptide antagonist of the neurokinin NK1 receptor, in dogs: identification of the novel cleaved product 5-trifluoromethoxy salicylic acid in plasma.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20070501